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Does Knockout of Sap25 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Sap25
cell proliferation
Embryonic Stem Cell Line
Gene: Sap25 (sin3 associated polypeptide) Type: protein-coding Summary: Involved in negative regulation of DNA-templated transcription. Is active in nucleus. Orthologous to human SAP25 (Sin3A associated protein 25). [provided by Alliance of Genome Resources, Jul 2025] Gene Ontology: BP: negativ...
Does Knockout of Mitf in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Mitf
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Mitf (melanogenesis associated transcription factor) Type: protein-coding Summary: This transcription factor serves at a critical point between extracellular signaling and downstream targets in cell specification in early eye and neural crest development. Mutant alleles have been identified that g...
Does Knockout of Mtif2 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Mtif2
cell proliferation
Colonic Cancer Cell Line
Gene: Mtif2 (mitochondrial translational initiation factor 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial translational initiation, ribosome disassembly, translation, translational initiation; MF: GTP binding, GTPase activity, nucleotide binding, ribosom...
Does Knockout of Srgn in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Srgn
cell proliferation
Embryonic Stem Cell Line
Gene: Srgn (serglycin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell secretory granule organization, apoptotic process, biomineral tissue development, granzyme-mediated programmed cell death signaling pathway, maintenance of granzyme B location in T cell secretor...
Does Knockout of Med4 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Med4
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Med4 (mediator complex subunit 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA polymerase II preinitiation complex assembly, positive regulation of DNA-templated transcription, positive regulation of transcription elongation by RNA polymerase II, positive reg...
Does Knockout of Ccnb2 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Ccnb2
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Ccnb2 (cyclin B2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G1/S transition of mitotic cell cycle, G2/MI transition of meiotic cell cycle, T cell homeostasis, cell division, in utero embryonic development, mitotic cell cycle phase transition, regulation of gro...
Does Knockout of Ankrd10 in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Ankrd10
protein/peptide accumulation
Mouse cell
Gene: Ankrd10 (ankyrin repeat domain 10) Type: protein-coding Summary: No summary available. Gene Ontology: CC: nucleoplasm Pathways: UniProt: Q99LW0 Entrez ID: 102334
Does Knockout of Gkn3 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
Gkn3
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Gkn3 (gastrokine 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of epithelial cell proliferation, regulation of cell population proliferation; CC: extracellular region, extracellular space Pathways: UniProt: Q9D0T7 ...
Does Knockout of Gga1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Gga1
cell proliferation
Mouse kidney carcinoma cell
Gene: Gga1 (golgi associated, gamma adaptin ear containing, ARF binding protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi to plasma membrane protein transport, Golgi to plasma membrane transport, intracellular protein localization, intracellular protein tra...
Does Knockout of Gm14819 in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Gm14819
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Gm14819 (predicted gene 14819) Type: protein-coding Summary: No summary available. Gene Ontology: CC: nucleus Pathways: UniProt: Q62478 Entrez ID: 100039585
Does Knockout of Serhl in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Serhl
protein/peptide distribution
myoblast cell line
Gene: Serhl (serine hydrolase-like) Type: protein-coding Summary: No summary available. Gene Ontology: MF: hydrolase activity; CC: cytoplasm, cytoplasmic vesicle, mitochondrion, perinuclear region of cytoplasm, peroxisome Pathways: UniProt: Q9EPB5 Entrez ID: 68607
Does Knockout of Tmem107 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Tmem107
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Tmem107 (transmembrane protein 107) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell projection organization, cilium assembly, cilium organization, craniofacial suture morphogenesis, detection of nodal flow, determination of left/right symmetry, embryonic digit ...
Does Knockout of 1700020N15Rik in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,044
Knockout
1700020N15Rik
autophagy
Embryonic Fibroblast Cell Line
Gene: 1700020N15Rik (RIKEN cDNA 1700020N15 gene) Type: ncRNA Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID: 75509
Does Knockout of Kmt2e in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Kmt2e
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Kmt2e (lysine (K)-specific methyltransferase 2E) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin organization, chromatin remodeling, epigenetic regulation of gene expression, erythrocyte differentiation, neutrophil activation, neutrophil mediated immunity,...
Does Knockout of Rif1 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Rif1
protein/peptide distribution
myoblast cell line
Gene: Rif1 (replication timing regulatory factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, cellular response to leukemia inhibitory factor, negative regulation of double-strand break repair via homologous recombination, negative r...
Does Knockout of Eif2b3 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Eif2b3
cell proliferation
Melanoma Cell Line
Gene: Eif2b3 (eukaryotic translation initiation factor 2B, subunit 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell receptor signaling pathway, central nervous system development, cytoplasmic translational initiation, oligodendrocyte development, response to gluc...
Does Knockout of Vmn1r222 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Vmn1r222
protein/peptide distribution
myoblast cell line
Gene: Vmn1r222 (vomeronasal 1 receptor 222) Type: protein-coding Summary: Predicted to enable pheromone binding activity and pheromone receptor activity. Predicted to act upstream of or within response to pheromone. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, A...
Does Knockout of Wrap73 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Wrap73
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Wrap73 (WD repeat containing, antisense to Trp73) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell projection organization, mitotic spindle assembly, positive regulation of non-motile cilium assembly; CC: MWP complex, centrosome, ciliary basal body, cytoplasm, c...
Does Knockout of Ppp1r7 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Ppp1r7
cell proliferation
Embryonic Stem Cell Line
Gene: Ppp1r7 (protein phosphatase 1, regulatory subunit 7) Type: protein-coding Summary: No summary available. Gene Ontology: MF: protein binding, protein phosphatase regulator activity; CC: chromosome, nucleus Pathways: UniProt: Q3UM45 Entrez ID: 66385
Does Knockout of Snx14 in Microglial Cell Line causally result in response to virus?
0
2,429
Knockout
Snx14
response to virus
Microglial Cell Line
Gene: Snx14 (sorting nexin 14) Type: protein-coding Summary: No summary available. Gene Ontology: BP: autophagosome maturation, postsynaptic modulation of chemical synaptic transmission, protein transport; MF: phosphatidylinositol binding, phosphatidylinositol-3,5-bisphosphate binding; CC: cell...
Does Knockout of Casp14 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Casp14
response to virus
Embryonic Fibroblast Cell Line
Gene: Casp14 (caspase 14) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, positive regulation of neuron apoptotic process, proteolysis; MF: cysteine-type endopeptidase activity, cysteine-type peptidase activity, hydrolase activity, peptidase activity...
Does Knockout of Mzt1 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Mzt1
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Mzt1 (mitotic spindle organizing protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: gamma-tubulin complex localization, microtubule nucleation by interphase microtubule organizing center, mitotic spindle assembly; CC: centrosome, cytoplasm, cytoskeleton, gam...
Does Knockout of Oas1f in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Oas1f
protein/peptide accumulation
Mouse cell
Gene: Oas1f (2'-5' oligoadenylate synthetase 1F) Type: protein-coding Summary: No summary available. Gene Ontology: BP: antiviral innate immune response, cellular response to exogenous dsRNA, cellular response to interferon-alpha, cellular response to interferon-beta, defense response to bacter...
Does Knockout of Rfc3 in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Rfc3
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Rfc3 (replication factor C (activator 1) 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA repair, DNA replication, DNA strand elongation involved in DNA replication, DNA-templated DNA replication, positive regulation of DNA-directed DNA polymerase activity; MF...
Does Knockout of Med28 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Med28
protein/peptide accumulation
Embryonic Cell Line
Gene: Med28 (mediator complex subunit 28) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA polymerase II preinitiation complex assembly, negative regulation of smooth muscle cell differentiation, positive regulation of transcription elongation by RNA polymerase II, pos...
Does Knockout of Dclk2 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Dclk2
protein/peptide distribution
myoblast cell line
Gene: Dclk2 (doublecortin-like kinase 2) Type: protein-coding Summary: This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization,...
Does Knockout of Cdc26 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Cdc26
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Cdc26 (cell division cycle 26) Type: protein-coding Summary: No summary available. Gene Ontology: BP: anaphase-promoting complex-dependent catabolic process, cell division, protein K11-linked ubiquitination, protein K48-linked ubiquitination, protein branched polyubiquitination, protein u...
Does Knockout of Hnrnpk in Regulatory T cell causally result in protein/peptide accumulation?
1
1,570
Knockout
Hnrnpk
protein/peptide accumulation
Regulatory T cell
Gene: Hnrnpk (heterogeneous nuclear ribonucleoprotein K) Type: protein-coding Summary: The protein encoded by this gene is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex, and is a poly-cytosine binding protein (PCBP). It is found in multiple subcellular compartments including...
Does Knockout of Icosl in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Icosl
cell proliferation
Embryonic Stem Cell Line
Gene: Icosl (icos ligand) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell activation, T cell activation, T cell receptor signaling pathway, T follicular helper cell differentiation, adaptive immune response, immune system process, isotype switching, positive regula...
Does Knockout of Sdhaf2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Sdhaf2
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Sdhaf2 (succinate dehydrogenase complex assembly factor 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial electron transport, succinate to ubiquinone, mitochondrial respiratory chain complex II assembly, negative regulation of canonical Wnt signaling ...
Does Knockout of Ugt1a10 in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Ugt1a10
protein/peptide distribution
myoblast cell line
Gene: Ugt1a10 (UDP glycosyltransferase 1 family, polypeptide A10) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: Ascorbate and aldarate metabolism - Mus musculus (mouse), Bile secretion - Mus musculus (mouse), Chemical carcinogenesis - DNA adducts - Mus m...
Does Knockout of Kcnj13 in Microglial Cell Line causally result in response to virus?
0
2,429
Knockout
Kcnj13
response to virus
Microglial Cell Line
Gene: Kcnj13 (potassium inwardly-rectifying channel, subfamily J, member 13) Type: protein-coding Summary: No summary available. Gene Ontology: BP: monoatomic ion transmembrane transport, monoatomic ion transport, potassium ion import across plasma membrane, potassium ion transmembrane transpor...
Does Knockout of Rps9 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Rps9
cell proliferation
Embryonic Stem Cell Line
Gene: Rps9 (ribosomal protein S9) Type: protein-coding Summary: A structural constituent of ribosome. Predicted to be involved in positive regulation of cell population proliferation; ribosomal small subunit biogenesis; and translation. Part of cytosolic small ribosomal subunit. Is active in synapse. Is...
Does Knockout of Sim1 in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
Sim1
response to virus
Embryonic Fibroblast Cell Line
Gene: Sim1 (single-minded family bHLH transcription factor 1) Type: protein-coding Summary: Enables protein heterodimerization activity. Involved in ureteric bud development. Acts upstream of or within regulation of DNA-templated transcription. Located in nucleus. Is expressed in several structures, inc...
Does Knockout of Bet1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Bet1
cell proliferation
Mouse kidney carcinoma cell
Gene: Bet1 (Bet1 golgi vesicular membrane trafficking protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: endoplasmic reticulum to Golgi vesicle-mediated transport, protein transport, vesicle fusion with Golgi apparatus, vesicle-mediated transport; MF: SNAP receptor ...
Does Knockout of Ube2g2 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Ube2g2
protein/peptide distribution
myoblast cell line
Gene: Ube2g2 (ubiquitin-conjugating enzyme E2G 2) Type: protein-coding Summary: Enables identical protein binding activity and ubiquitin conjugating enzyme activity. Acts upstream of or within ERAD pathway. Located in cytosol and endoplasmic reticulum. Is expressed in several structures, including alime...
Does Knockout of Mcoln3 in Melanoma Cell Line causally result in cell proliferation?
1
2,492
Knockout
Mcoln3
cell proliferation
Melanoma Cell Line
Gene: Mcoln3 (mucolipin 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: calcium-mediated signaling, inner ear auditory receptor cell differentiation, locomotory behavior, monoatomic anion transmembrane transport, monoatomic cation transmembrane transport, monoatomic io...
Does Knockout of Smok3a in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Smok3a
cell cycle progression
breast epithelium
Gene: Smok3a (sperm motility kinase 3A) Type: protein-coding Summary: No summary available. Gene Ontology: MF: ATP binding, kinase activity, nucleotide binding, protein kinase activity, protein serine kinase activity, protein serine/threonine kinase activity, transferase activity Pathw...
Does Knockout of Gle1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Gle1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Gle1 (GLE1 RNA export mediator) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mRNA export from nucleus, mRNA transport, nucleocytoplasmic transport, poly(A)+ mRNA export from nucleus, protein transport; MF: identical protein binding, inositol hexakisphosphate bind...
Does Knockout of Ddx21 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,307
Knockout
Ddx21
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Ddx21 (DExD box helicase 21) Type: protein-coding Summary: No summary available. Gene Ontology: BP: R-loop processing, chromatin remodeling, defense response to virus, immune system process, innate immune response, positive regulation of canonical NF-kappaB signal transduction, positive r...
Does Knockout of Pde10a in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,174
Knockout
Pde10a
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Pde10a (phosphodiesterase 10A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cAMP catabolic process, cGMP catabolic process, negative regulation of cAMP/PKA signal transduction, negative regulation of cGMP-mediated signaling, regulation of adenylate cyclase-activa...
Does Knockout of Ybx1 in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Ybx1
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Ybx1 (Y box protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: CRD-mediated mRNA stabilization, RNA splicing, RNA transport, cellular response to interleukin-7, embryonic morphogenesis, epidermis development, in utero embryonic development, mRNA processing, ...
Does Knockout of Spa17 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
81
Knockout
Spa17
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Spa17 (sperm autoantigenic protein 17) Type: protein-coding Summary: No summary available. Gene Ontology: BP: binding of sperm to zona pellucida, single fertilization; CC: cilium, cytoplasm, external side of plasma membrane, membrane, motile cilium, neuron projection, sperm fibrous sheath...
Does Knockout of Srsf12 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Srsf12
protein/peptide distribution
myoblast cell line
Gene: Srsf12 (serine and arginine-rich splicing factor 12) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, mRNA 5'-splice site recognition, mRNA processing, regulation of alternative mRNA splicing, via spliceosome Pathways: UniProt: Q8C8K3...
Does Knockout of Unc45a in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Unc45a
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Unc45a (unc-45 myosin chaperone A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, muscle organ development, protein folding; MF: Hsp90 protein binding, protein binding; CC: Golgi apparatus, cytoplasm, cytosol, nuclear speck, nucleus, perinucle...
Does Knockout of Cd79a in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Cd79a
protein/peptide distribution
myoblast cell line
Gene: Cd79a (CD79A antigen (immunoglobulin-associated alpha)) Type: protein-coding Summary: Enables transmembrane signaling receptor activity. Involved in B cell differentiation; B cell proliferation; and B cell receptor signaling pathway. Located in external side of plasma membrane; membrane raft; and ...
Does Knockout of Anapc2 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Anapc2
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Anapc2 (anaphase promoting complex subunit 2) Type: protein-coding Summary: This gene encodes a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle by ubiquitinating its ...
Does Knockout of Jak2 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Jak2
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Jak2 (Janus kinase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T-helper 1 cell differentiation, activation of Janus kinase activity, adaptive immune response, apoptotic signaling pathway, axon regeneration, cell adhesion, cell differentiation, cell surface re...
Does Knockout of Dctn3 in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Dctn3
cell proliferation
Melanoma Cell Line
Gene: Dctn3 (dynactin 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, cytoskeleton-dependent cytokinesis, microtubule-based process; CC: centrosome, chromosome, chromosome, centromeric region, cleavage furrow, cytoplasm, cytoskeleton, cytosol, dynactin c...
Does Knockout of Taf1a in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Taf1a
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Taf1a (TATA-box binding protein associated factor, RNA polymerase I, A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: transcription by RNA polymerase I; MF: DNA binding, protein binding; CC: RNA polymerase I transcription regulator complex, RNA polymerase transcri...
Does Knockout of Nudc in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Nudc
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Nudc (nudC nuclear distribution protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, establishment of organelle localization, mitotic metaphase chromosome alignment, mitotic spindle organization, nuclear migration, protein folding, response to pep...
Does Knockout of Hook1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Hook1
cell proliferation
Mouse kidney carcinoma cell
Gene: Hook1 (hook microtubule tethering protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi organization, cell differentiation, cytoplasmic microtubule organization, cytoskeleton-dependent intracellular transport, early endosome to late endosome transport, en...
Does Knockout of Ndufb10 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Ndufb10
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ndufb10 (NADH:ubiquinone oxidoreductase subunit B10) Type: protein-coding Summary: No summary available. Gene Ontology: BP: aerobic respiration, proton motive force-driven mitochondrial ATP synthesis; CC: membrane, mitochondrial inner membrane, mitochondrion, respiratory chain complex I ...
Does Knockout of Thap1 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Thap1
cell proliferation
Melanoma Cell Line
Gene: Thap1 (THAP domain containing, apoptosis associated protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA-templated transcription, endothelial cell proliferation, negative regulation of transcription by RNA polymerase II, regulation of DNA-templated transcr...
Does Knockout of Nr1h2 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
1
2,171
Knockout
Nr1h2
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Nr1h2 (nuclear receptor subfamily 1, group H, member 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, cholesterol homeostasis, hormone-mediated signaling pathway, intracellular receptor signaling pathway, lipid homeostasis, lipid metabolic pr...
Does Knockout of Jpt1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Jpt1
cell proliferation
Mouse kidney carcinoma cell
Gene: Jpt1 (Jupiter microtubule associated homolog 1) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cytoplasm, cytosol, intercellular bridge, microtubule cytoskeleton, nucleoplasm, nucleus Pathways: UniProt: P97825 Entrez ID: 15374
Does Knockout of Ctu2 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Ctu2
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Ctu2 (cytosolic thiouridylase subunit 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein urmylation, tRNA processing, tRNA thio-modification, tRNA wobble position uridine thiolation, tRNA wobble uridine modification; MF: nucleotidyltransferase activity, sulf...
Does Knockout of Ckap2l in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Ckap2l
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ckap2l (cytoskeleton associated protein 2-like) Type: protein-coding Summary: No summary available. Gene Ontology: CC: centrosome, cilium, cytoplasm, cytoskeleton, cytosol, microtubule cytoskeleton, mitotic spindle, spindle pole Pathways: UniProt: Q7TS74 Entrez ...
Does Knockout of Dusp6 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,171
Knockout
Dusp6
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Dusp6 (dual specificity phosphatase 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, negative regulation of ERK1 and ERK2 cascade, negative regulation of MAPK cascade, positive regulation of apoptotic process, regulation of heart growth, resp...
Does Knockout of Ccnk in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,290
Knockout
Ccnk
cell proliferation
Mouse kidney carcinoma cell
Gene: Ccnk (cyclin K) Type: protein-coding Summary: Predicted to enable cyclin-dependent protein serine/threonine kinase activator activity; protein kinase binding activity; and protein serine/threonine kinase activity. Acts upstream of or within in utero embryonic development and negative regulation of...
Does Knockout of Sin3b in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Sin3b
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Sin3b (transcriptional regulator, SIN3B (yeast)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cardiac muscle tissue development, negative regulation of DNA-templated transcription, negative regulation of cell cycle, negative regulation of cell migration, negative...
Does Knockout of Mrgprh in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Mrgprh
protein/peptide distribution
myoblast cell line
Gene: Mrgprh (MAS-related GPR, member H) Type: protein-coding Summary: Predicted to enable angiotensin receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2025] Gen...
Does Knockout of Cypt2 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Cypt2
protein/peptide accumulation
Embryonic Cell Line
Gene: Cypt2 (cysteine-rich perinuclear theca 2) Type: protein-coding Summary: cysteine-rich perinuclear theca 2 Gene Ontology: Pathways: UniProt: Q8CH23, Q6P924, A0A9L6KE70 Entrez ID: 245566
Does Knockout of Ndufa6 in Embryonic Fibroblast Cell Line causally result in protein/peptide accumulation?
0
2,474
Knockout
Ndufa6
protein/peptide accumulation
Embryonic Fibroblast Cell Line
Gene: Ndufa6 (NADH:ubiquinone oxidoreductase subunit A6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: aerobic respiration, mitochondrial respiratory chain complex I assembly, proton motive force-driven mitochondrial ATP synthesis; CC: membrane, mitochondrial inner memb...
Does Knockout of Gnb1l in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Gnb1l
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Gnb1l (guanine nucleotide binding protein (G protein), beta polypeptide 1-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage checkpoint signaling, DNA damage response, social behavior; CC: cytoplasm, nucleus Pathways: UniProt: Q9EQ15...
Does Knockout of Cnnm3 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Cnnm3
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Cnnm3 (cyclin M3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: magnesium ion homeostasis, monoatomic ion transport, transmembrane transport; CC: membrane, plasma membrane Pathways: UniProt: Q32NY4 Entrez ID: 94218
Does Knockout of Smc6 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Smc6
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Smc6 (structural maintenance of chromosomes 6) Type: protein-coding Summary: Predicted to enable DNA binding activity and ubiquitin protein ligase binding activity. Predicted to be involved in several processes, including DNA recombination; cellular senescence; and negative regulation by host of v...
Does Knockout of E130308A19Rik in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
E130308A19Rik
protein/peptide accumulation
Regulatory T cell
Gene: E130308A19Rik (RIKEN cDNA E130308A19 gene) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q8C4P0 Entrez ID: 230259
Does Knockout of Tmem151a in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Tmem151a
protein/peptide distribution
myoblast cell line
Gene: Tmem151a (transmembrane protein 151A) Type: protein-coding Summary: No summary available. Gene Ontology: CC: T-tubule, axon, cell projection, cellular_component, dendrite, endoplasmic reticulum, endoplasmic reticulum membrane, membrane Pathways: UniProt: Q6GQT5 ...
Does Knockout of Vmn1r197 in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Vmn1r197
protein/peptide distribution
myoblast cell line
Gene: Vmn1r197 (vomeronasal 1 receptor 197) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, response to pheromone, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled receptor activity, pheromon...
Does Knockout of Gtf2h2 in Lymphoma Cell Line causally result in response to chemicals?
0
1,541
Knockout
Gtf2h2
response to chemicals
Lymphoma Cell Line
Gene: Gtf2h2 (general transcription factor II H, polypeptide 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, DNA-templated transcription, nucleotide-excision repair, regulation of transcription by RNA polymerase II, transcription by RNA...
Does Knockout of Tmprss11c in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Tmprss11c
protein/peptide distribution
myoblast cell line
Gene: Tmprss11c (transmembrane protease, serine 11c) Type: protein-coding Summary: No summary available. Gene Ontology: BP: proteolysis, self proteolysis; MF: hydrolase activity, peptidase activity, serine-type endopeptidase activity, serine-type peptidase activity; CC: cell projection, dendrit...
Does Knockout of Tas2r119 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Tas2r119
protein/peptide distribution
myoblast cell line
Gene: Tas2r119 (taste receptor, type 2, member 119) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, detection of chemical stimulus involved in sensory perception of bitter taste, detection of chemical stimulus involved in sens...
Does Knockout of Exoc5 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Exoc5
cell proliferation
Mouse kidney carcinoma cell
Gene: Exoc5 (exocyst complex component 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi to plasma membrane transport, epithelial cell apoptotic process, establishment of planar polarity, exocytosis, homeostasis of number of cells within a tissue, membrane fission,...
Does Knockout of Mapk9 in Embryonic Stem Cell Line causally result in cell proliferation?
0
579
Knockout
Mapk9
cell proliferation
Embryonic Stem Cell Line
Gene: Mapk9 (mitogen-activated protein kinase 9) Type: protein-coding Summary: No summary available. Gene Ontology: BP: JNK cascade, cellular response to UV, cellular response to reactive oxygen species, extrinsic apoptotic signaling pathway, inflammatory response to wounding, mRNA destabilizat...
Does Knockout of Ric3 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
Ric3
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Ric3 (RIC3 acetylcholine receptor chaperone) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of cytosolic calcium ion concentration, positive regulation of protein localization to cell surface, protein folding, protein localization to cell surfac...
Does Knockout of C1qtnf5 in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
C1qtnf5
cell cycle progression
breast epithelium
Gene: C1qtnf5 (C1q and tumor necrosis factor related protein 5) Type: protein-coding Summary: The protein encoded by this gene is a member of the C1q/tumor necrosis factor superfamily. This family member is a secretory protein that functions in eye development. Mutations in this gene are thought to unde...
Does Knockout of Lgi3 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Lgi3
protein/peptide distribution
myoblast cell line
Gene: Lgi3 (leucine-rich repeat LGI family, member 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: exocytosis, regulation of exocytosis; CC: axon, cell projection, cytoplasmic vesicle, extracellular region, extracellular space, juxtaparanode region of axon, neuron proj...
Does Knockout of Phkb in Regulatory T cell causally result in cell proliferation?
0
2,127
Knockout
Phkb
cell proliferation
Regulatory T cell
Gene: Phkb (phosphorylase kinase beta) Type: protein-coding Summary: No summary available. Gene Ontology: BP: carbohydrate metabolic process, glucose homeostasis, glycogen metabolic process, positive regulation of glycogen catabolic process; CC: membrane, phosphorylase kinase complex, plasma me...
Does Knockout of Arl6ip4 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Arl6ip4
cell proliferation
Mouse kidney carcinoma cell
Gene: Arl6ip4 (ADP-ribosylation factor-like 6 interacting protein 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, mRNA processing; CC: nuclear speck, nucleolus, nucleus Pathways: UniProt: Q9JM93 Entrez ID: 65105
Does Knockout of Gm16451 in macrophage causally result in phagocytosis?
0
1,888
Knockout
Gm16451
phagocytosis
macrophage
Gene: Gm16451 (predicted pseudogene 16451) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, biological_process, response to pheromone, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled receptor...
Does Knockout of Skint10 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Skint10
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Skint10 (selection and upkeep of intraepithelial T cells 10) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell receptor signaling pathway, regulation of cytokine production; CC: external side of plasma membrane, membrane Pathways: UniProt: A7...
Does Knockout of Mybl1 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Mybl1
response to chemicals
Pancreatic Cancer Cell Line
Gene: Mybl1 (myeloblastosis oncogene-like 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, male meiosis I, mitotic cell cycle, positive regulation of piRNA transcription, positive regulation of transcription by RNA polymerase II, regulation of DNA-...
Does Knockout of Spen in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
1,130
Knockout
Spen
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Spen (spen family transcription repressor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Notch signaling pathway, negative regulation of DNA-templated transcription, negative regulation of transcription by RNA polymerase II, positive regulation of DNA-templated tr...
Does Knockout of Vmn2r116 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Vmn2r116
protein/peptide accumulation
Embryonic Cell Line
Gene: Vmn2r116 (vomeronasal 2, receptor 116) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, positive regulation of female receptivity, response to pheromone, signal transduction; MF: G protein-coupled receptor activity, phero...
Does Knockout of Eif2s2 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Eif2s2
cell proliferation
Embryonic Stem Cell Line
Gene: Eif2s2 (eukaryotic translation initiation factor 2 subunit 2 beta) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic translational initiation, formation of translation preinitiation complex, in utero embryonic development, male germ cell proliferation, mal...
Does Knockout of Rps4x in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Rps4x
cell viability
Immortal mouse chromaffin cells
Gene: Rps4x (ribosomal protein S4, X-linked) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic translation, positive regulation of cell population proliferation, positive regulation of translation, ribosomal small subunit biogenesis, translation; MF: RNA binding...
Does Knockout of Wdr20 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Wdr20
protein/peptide accumulation
Embryonic Cell Line
Gene: Wdr20 (WD repeat domain 20) Type: protein-coding Summary: No summary available. Gene Ontology: MF: deubiquitinase activator activity, molecular_function; CC: cellular_component, cytoplasm, nucleus Pathways: Deubiquitination, Metabolism of proteins, Post-translational protein modi...
Does Knockout of Prdm16 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Prdm16
cell viability
Immortal mouse chromaffin cells
Gene: Prdm16 (PR domain containing 16) Type: protein-coding Summary: No summary available. Gene Ontology: BP: beige fat cell differentiation, brown fat cell differentiation, cell differentiation, chromatin remodeling, heterochromatin organization, maintenance of cell number, methylation, negati...
Does Knockout of Sv2b in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
Sv2b
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Sv2b (synaptic vesicle glycoprotein 2b) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chemical synaptic transmission, neurotransmitter transport, regulation of presynaptic cytosolic calcium ion concentration, regulation of synaptic vesicle exocytosis, transmembran...
Does Knockout of Babam1 in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
Babam1
response to virus
Embryonic Fibroblast Cell Line
Gene: Babam1 (BRISC and BRCA1 A complex member 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, DNA repair-dependent chromatin remodeling, cell division, chromatin organization, double-strand break repair, hematopoietic stem cell prolife...
Does Knockout of Kat2a in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,275
Knockout
Kat2a
cell proliferation
Colonic Cancer Cell Line
Gene: Kat2a (K(lysine) acetyltransferase 2A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to nerve growth factor stimulus, cellular response to tumor necrosis factor, chromatin remodeling, fibroblast proliferation, gluconeogenesis, heart development, ...
Does Knockout of Ybx2 in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Ybx2
cell proliferation
Melanoma Cell Line
Gene: Ybx2 (Y box protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mRNA stabilization, negative regulation of RNA metabolic process, negative regulation of macromolecule biosynthetic process, negative regulation of translation, oogenesis, positive regulation of ...
Does Knockout of Cebpz in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Cebpz
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Cebpz (CCAAT/enhancer binding protein zeta) Type: protein-coding Summary: No summary available. Gene Ontology: CC: CCAAT-binding factor complex, nucleoplasm, nucleus Pathways: UniProt: P53569 Entrez ID: 12607
Does Knockout of Atad2b in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Atad2b
protein/peptide distribution
Microglial Cell Line
Gene: Atad2b (ATPase family, AAA domain containing 2B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: nucleosome assembly, nucleosome disassembly, transcription initiation-coupled chromatin remodeling; MF: ATP binding, ATP hydrolysis activity, chromatin binding, histone ...
Does Knockout of Zfp593 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Zfp593
protein/peptide distribution
myoblast cell line
Gene: Zfp593 (zinc finger protein 593) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of transcription by RNA polymerase II, ribosome biogenesis; MF: DNA binding, metal ion binding, nucleic acid binding, preribosome binding, ribonucleoprotein complex ...
Does Knockout of Gnpat in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Gnpat
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Gnpat (glyceronephosphate O-acyltransferase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cerebellum morphogenesis, ether lipid biosynthetic process, glycerophospholipid metabolic process, lipid metabolic process, membrane organization, myelination, paranodal jun...
Does Knockout of Taar7f in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Taar7f
cell proliferation
Melanoma Cell Line
Gene: Taar7f (trace amine-associated receptor 7F) Type: protein-coding Summary: Enables trace-amine receptor activity. Involved in sensory perception of chemical stimulus. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human TAAR7P (trace amine associated ...
Does Knockout of Hic2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Hic2
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Hic2 (hypermethylated in cancer 2) Type: protein-coding Summary: No summary available. Gene Ontology: MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, metal ion binding, zinc ion binding; CC: nucleoplasm, nucleus, plasma membrane Pathways: ...
Does Knockout of Defa24 in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Defa24
protein/peptide distribution
myoblast cell line
Gene: Defa24 (defensin, alpha, 24) Type: protein-coding Summary: No summary available. Gene Ontology: BP: antibacterial humoral response, antimicrobial humoral immune response mediated by antimicrobial peptide, defense response, defense response to Gram-negative bacterium, defense response to G...