Datasets:

uuid
stringlengths
4
8
template_uuid
stringclasses
40 values
question
stringlengths
13
193
answer
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29
2.2k
benchmark_query
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138
627
execution_results
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2
1.14M
query_type
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2 values
sql_category
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26 values
bio_category
stringclasses
14 values
Q10.1756
Q10
Are there any SIM1 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within SIM1 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'SIM1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1669
Q10
Are there any CELA1 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within CELA1 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'CELA1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.533
Q10
Are there any FAM76B SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within FAM76B that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'FAM76B' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1821
Q10
Are there any SMIM41 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within SMIM41 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'SMIM41' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1442
Q10
Are there any KLHL7-AS1 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within KLHL7-AS1 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'KLHL7-AS1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.302
Q10
Are there any UBE4A SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within UBE4A that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'UBE4A' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1016
Q10
Are there any LRRC37A17P SNPs that have a statistically significant association with Parkinson's Disease?
Yes, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there is at least 1 LRRC37A17P SNP that are significantly associatied with Parkinson's Disease: • rs4630591 (GWAS p-value: 2.94e-20; b-value: -0.2462)
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'LRRC37A17P' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_1242291', 'Gene': 'LRRC37A17P', 'topRSID': 'rs4630591', 'p_GWAS': 2.944142e-20, 'b_GWAS': -0.2462}]
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Q10.1417
Q10
Are there any TREM2 SNPs that have a statistically significant association with Alzheimer's Disease?
Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there is at least 1 TREM2 SNP that are significantly associatied with Alzheimer's Disease: • rs9394778 (GWAS p-value: 2.53e-10; b-value: 0.0525)
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'TREM2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_1109138', 'Gene': 'TREM2', 'topRSID': 'rs9394778', 'p_GWAS': 2.527391e-10, 'b_GWAS': 0.0525}]
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Q10.1567
Q10
Are there any MNS1 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within MNS1 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'MNS1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1311
Q10
Are there any NFYA SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within NFYA that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'NFYA' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.862
Q10
Are there any RP11-395A13.2 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within RP11-395A13.2 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'RP11-395A13.2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.591
Q10
Are there any RP11-114G22.1 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within RP11-114G22.1 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'RP11-114G22.1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.485
Q10
Are there any CHRD SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within CHRD that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'CHRD' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1473
Q10
Are there any GRIFIN SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within GRIFIN that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'GRIFIN' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1784
Q10
Are there any PSCA SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within PSCA that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'PSCA' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.644
Q10
Are there any SARM1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within SARM1 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'SARM1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.357
Q10
Are there any RNA5SP219 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within RNA5SP219 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'RNA5SP219' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1128
Q10
Are there any GAK SNPs that have a statistically significant association with Parkinson's Disease?
Yes, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there is at least 18 GAK SNP that are significantly associatied with Parkinson's Disease: • rs6599388 (GWAS p-value: 7.14e-21; b-value: -0.179) • rs11248057 (GWAS p-value: 1.48e-20; b-value: -0.1831) • rs3775122 (GWAS p-value: 8.63e-10; b-value: 0.1754) • rs2279182 (GWAS p-value: 1.43e-09; b-value: -0.1731) • rs10029038 (GWAS p-value: 1.45e-09; b-value: 0.1718) • rs6842808 (GWAS p-value: 1.55e-09; b-value: -0.1715) • rs748483 (GWAS p-value: 1.72e-09; b-value: -0.165) • rs17165130 (GWAS p-value: 2.60e-09; b-value: -0.1328) • rs2279181 (GWAS p-value: 4.64e-09; b-value: -0.1752) • rs11248051 (GWAS p-value: 1.32e-08; b-value: -0.1631)
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'GAK' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_429801', 'Gene': 'GAK', 'topRSID': 'rs6599388', 'p_GWAS': 7.135477e-21, 'b_GWAS': -0.179}, {'UUID': 'NDD_SMR_genes_all_update_text_429829', 'Gene': 'GAK', 'topRSID': 'rs11248057', 'p_GWAS': 1.4801619999999998e-20, 'b_GWAS': -0.1831}, {'UUID': 'NDD_SMR_genes_all_update_text_429830', 'Gene': 'GAK', 'topRSID': 'rs11248057', 'p_GWAS': 1.4801619999999998e-20, 'b_GWAS': -0.1831}, {'UUID': 'NDD_SMR_genes_all_update_text_429834', 'Gene': 'GAK', 'topRSID': 'rs11248057', 'p_GWAS': 1.4801619999999998e-20, 'b_GWAS': -0.1831}, {'UUID': 'NDD_SMR_genes_all_update_text_429832', 'Gene': 'GAK', 'topRSID': 'rs11248057', 'p_GWAS': 1.4801619999999998e-20, 'b_GWAS': -0.1831}, {'UUID': 'NDD_SMR_genes_all_update_text_1430182', 'Gene': 'GAK', 'topRSID': 'rs11248057', 'p_GWAS': 1.4801619999999998e-20, 'b_GWAS': 0.1831}, {'UUID': 'NDD_SMR_genes_all_update_text_429831', 'Gene': 'GAK', 'topRSID': 'rs11248057', 'p_GWAS': 1.4801619999999998e-20, 'b_GWAS': -0.1831}, {'UUID': 'NDD_SMR_genes_all_update_text_1635860', 'Gene': 'GAK', 'topRSID': 'rs11248057', 'p_GWAS': 1.4801619999999998e-20, 'b_GWAS': -0.1831}, {'UUID': 'NDD_SMR_genes_all_update_text_996274', 'Gene': 'GAK', 'topRSID': 'rs3775122', 'p_GWAS': 8.630923e-10, 'b_GWAS': 0.1754}, {'UUID': 'NDD_SMR_genes_all_update_text_429819', 'Gene': 'GAK', 'topRSID': 'rs2279182', 'p_GWAS': 1.426615e-09, 'b_GWAS': -0.1731}, {'UUID': 'NDD_SMR_genes_all_update_text_996280', 'Gene': 'GAK', 'topRSID': 'rs10029038', 'p_GWAS': 1.454804e-09, 'b_GWAS': 0.1718}, {'UUID': 'NDD_SMR_genes_all_update_text_429835', 'Gene': 'GAK', 'topRSID': 'rs6842808', 'p_GWAS': 1.553296e-09, 'b_GWAS': -0.1715}, {'UUID': 'NDD_SMR_genes_all_update_text_429806', 'Gene': 'GAK', 'topRSID': 'rs748483', 'p_GWAS': 1.723837e-09, 'b_GWAS': -0.165}, {'UUID': 'NDD_SMR_genes_all_update_text_996279', 'Gene': 'GAK', 'topRSID': 'rs17165130', 'p_GWAS': 2.598224e-09, 'b_GWAS': 0.1328}, {'UUID': 'NDD_SMR_genes_all_update_text_429813', 'Gene': 'GAK', 'topRSID': 'rs17165130', 'p_GWAS': 2.598224e-09, 'b_GWAS': -0.1328}, {'UUID': 'NDD_SMR_genes_all_update_text_429814', 'Gene': 'GAK', 'topRSID': 'rs17165130', 'p_GWAS': 2.598224e-09, 'b_GWAS': -0.1328}, {'UUID': 'NDD_SMR_genes_all_update_text_429812', 'Gene': 'GAK', 'topRSID': 'rs17165130', 'p_GWAS': 2.598224e-09, 'b_GWAS': -0.1328}, {'UUID': 'NDD_SMR_genes_all_update_text_429833', 'Gene': 'GAK', 'topRSID': 'rs2279181', 'p_GWAS': 4.641741e-09, 'b_GWAS': -0.1752}, {'UUID': 'NDD_SMR_genes_all_update_text_429807', 'Gene': 'GAK', 'topRSID': 'rs11248051', 'p_GWAS': 1.324089e-08, 'b_GWAS': -0.1631}, {'UUID': 'NDD_SMR_genes_all_update_text_429800', 'Gene': 'GAK', 'topRSID': 'rs78590562', 'p_GWAS': 1.36119e-08, 'b_GWAS': 0.1641}, {'UUID': 'NDD_SMR_genes_all_update_text_1323349', 'Gene': 'GAK', 'topRSID': 'rs4690202', 'p_GWAS': 1.73268e-08, 'b_GWAS': 0.1257}, {'UUID': 'NDD_SMR_genes_all_update_text_429817', 'Gene': 'GAK', 'topRSID': 'rs3775127', 'p_GWAS': 1.825197e-08, 'b_GWAS': -0.1255}, {'UUID': 'NDD_SMR_genes_all_update_text_429828', 'Gene': 'GAK', 'topRSID': 'rs3775127', 'p_GWAS': 1.825197e-08, 'b_GWAS': -0.1255}, {'UUID': 'NDD_SMR_genes_all_update_text_429818', 'Gene': 'GAK', 'topRSID': 'rs3775127', 'p_GWAS': 1.825197e-08, 'b_GWAS': -0.1255}, {'UUID': 'NDD_SMR_genes_all_update_text_1140274', 'Gene': 'GAK', 'topRSID': 'rs4690204', 'p_GWAS': 1.973028e-08, 'b_GWAS': -0.1252}, {'UUID': 'NDD_SMR_genes_all_update_text_996273', 'Gene': 'GAK', 'topRSID': 'rs12651271', 'p_GWAS': 2.02612e-08, 'b_GWAS': 0.161}, {'UUID': 'NDD_SMR_genes_all_update_text_996257', 'Gene': 'GAK', 'topRSID': 'rs12651271', 'p_GWAS': 2.02612e-08, 'b_GWAS': 0.161}, {'UUID': 'NDD_SMR_genes_all_update_text_429796', 'Gene': 'GAK', 'topRSID': 'rs73207791', 'p_GWAS': 2.798912e-08, 'b_GWAS': -0.1244}, {'UUID': 'NDD_SMR_genes_all_update_text_996261', 'Gene': 'GAK', 'topRSID': 'rs73207790', 'p_GWAS': 2.798912e-08, 'b_GWAS': 0.1244}, {'UUID': 'NDD_SMR_genes_all_update_text_429797', 'Gene': 'GAK', 'topRSID': 'rs3775119', 'p_GWAS': 3.023259e-08, 'b_GWAS': -0.1313}]
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Q10.439
Q10
Are there any KLHL2 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within KLHL2 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'KLHL2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1121
Q10
Are there any RP11-244F12.3 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within RP11-244F12.3 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'RP11-244F12.3' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1103
Q10
Are there any ZDBF2 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within ZDBF2 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'ZDBF2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1348
Q10
Are there any SYNJ1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within SYNJ1 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'SYNJ1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.597
Q10
Are there any LAMC3 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within LAMC3 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'LAMC3' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1368
Q10
Are there any LINC01059 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within LINC01059 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'LINC01059' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1401
Q10
Are there any IGHG3 SNPs that have a statistically significant association with Alzheimer's Disease?
Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there is at least 1 IGHG3 SNP that are significantly associatied with Alzheimer's Disease: • rs74093865 (GWAS p-value: 2.78e-08; b-value: 0.0611)
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'IGHG3' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_1651660', 'Gene': 'IGHG3', 'topRSID': 'rs74093865', 'p_GWAS': 2.783351e-08, 'b_GWAS': 0.0611}]
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Q10.753
Q10
Are there any POU1F1 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within POU1F1 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'POU1F1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.259
Q10
Are there any MALSU1 SNPs that have a statistically significant association with Parkinson's Disease?
Yes, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there is at least 1 MALSU1 SNP that are significantly associatied with Parkinson's Disease: • rs274058 (GWAS p-value: 6.50e-09; b-value: -0.1033)
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'MALSU1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_1557765', 'Gene': 'MALSU1', 'topRSID': 'rs274058', 'p_GWAS': 6.499484e-09, 'b_GWAS': -0.1033}]
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Q10.1687
Q10
Are there any LOC283999 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within LOC283999 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'LOC283999' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
refined
Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1723
Q10
Are there any EVPL SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within EVPL that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'EVPL' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
refined
Distinct, Multi-Filter, Order By
GWAS Significance
Q10.544
Q10
Are there any NBEAL1 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within NBEAL1 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'NBEAL1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
refined
Distinct, Multi-Filter, Order By
GWAS Significance
Q10.792
Q10
Are there any MPP5 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within MPP5 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'MPP5' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1484
Q10
Are there any PLA2G3 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within PLA2G3 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'PLA2G3' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
refined
Distinct, Multi-Filter, Order By
GWAS Significance
Q10.420
Q10
Are there any SNORA71D SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within SNORA71D that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'SNORA71D' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
refined
Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1849
Q10
Are there any TMF1 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within TMF1 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'TMF1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1920
Q10
Are there any RP11-797H7.5 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within RP11-797H7.5 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'RP11-797H7.5' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1099
Q10
Are there any CGN SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within CGN that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'CGN' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
refined
Distinct, Multi-Filter, Order By
GWAS Significance
Q10.845
Q10
Are there any ARMC4 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within ARMC4 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'ARMC4' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.68
Q10
Are there any CLPTM1 SNPs that have a statistically significant association with Alzheimer's Disease?
Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 4 CLPTM1 SNPs that are significantly associatied with Alzheimer's Disease: • rs112704499 (GWAS p-value: 6.53e-10; b-value: 0.0593) • rs2239375 (GWAS p-value: 3.09e-20; b-value: 0.0811) • rs12460352 (GWAS p-value: 4.91e-21; b-value: 0.0847) • rs112784534 (GWAS p-value: 1.58e-30; b-value: -0.1091)
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'CLPTM1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_1108032', 'Gene': 'CLPTM1', 'topRSID': 'rs112784534', 'p_GWAS': 1.583756e-30, 'b_GWAS': -0.1091}, {'UUID': 'NDD_SMR_genes_all_update_text_637441', 'Gene': 'CLPTM1', 'topRSID': 'rs12460352', 'p_GWAS': 4.909195e-21, 'b_GWAS': 0.0847}, {'UUID': 'NDD_SMR_genes_all_update_text_637440', 'Gene': 'CLPTM1', 'topRSID': 'rs2239375', 'p_GWAS': 3.086516e-20, 'b_GWAS': 0.0811}, {'UUID': 'NDD_SMR_genes_all_update_text_122472', 'Gene': 'CLPTM1', 'topRSID': 'rs112704499', 'p_GWAS': 6.529661e-10, 'b_GWAS': 0.0593}]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1698
Q10
Are there any SNX31 SNPs that have a statistically significant association with Alzheimer's Disease?
Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 4 SNX31 SNPs that are significantly associatied with Alzheimer's Disease: • rs1693568 (GWAS p-value: 2.50e-08; b-value: -0.0457) • rs1693551 (GWAS p-value: 1.46e-08; b-value: -0.0459) • rs1693560 (GWAS p-value: 3.54e-08; b-value: 0.0452) • rs2978102 (GWAS p-value: 3.54e-08; b-value: 0.0452)
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'SNX31' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_1377800', 'Gene': 'SNX31', 'topRSID': 'rs1693551', 'p_GWAS': 1.456022e-08, 'b_GWAS': 0.0459}, {'UUID': 'NDD_SMR_genes_all_update_text_79524', 'Gene': 'SNX31', 'topRSID': 'rs1693551', 'p_GWAS': 1.456022e-08, 'b_GWAS': -0.0459}, {'UUID': 'NDD_SMR_genes_all_update_text_1340611', 'Gene': 'SNX31', 'topRSID': 'rs1693551', 'p_GWAS': 1.456022e-08, 'b_GWAS': 0.0459}, {'UUID': 'NDD_SMR_genes_all_update_text_1173074', 'Gene': 'SNX31', 'topRSID': 'rs1693551', 'p_GWAS': 1.456022e-08, 'b_GWAS': 0.0459}, {'UUID': 'NDD_SMR_genes_all_update_text_1288287', 'Gene': 'SNX31', 'topRSID': 'rs1693551', 'p_GWAS': 1.456022e-08, 'b_GWAS': 0.0459}, {'UUID': 'NDD_SMR_genes_all_update_text_1688163', 'Gene': 'SNX31', 'topRSID': 'rs1693551', 'p_GWAS': 1.456022e-08, 'b_GWAS': 0.0459}, {'UUID': 'NDD_SMR_genes_all_update_text_1266927', 'Gene': 'SNX31', 'topRSID': 'rs1693551', 'p_GWAS': 1.456022e-08, 'b_GWAS': 0.0459}, {'UUID': 'NDD_SMR_genes_all_update_text_28327', 'Gene': 'SNX31', 'topRSID': 'rs1693568', 'p_GWAS': 2.501442e-08, 'b_GWAS': -0.0457}, {'UUID': 'NDD_SMR_genes_all_update_text_24650', 'Gene': 'SNX31', 'topRSID': 'rs1693568', 'p_GWAS': 2.501442e-08, 'b_GWAS': -0.0457}, {'UUID': 'NDD_SMR_genes_all_update_text_30673', 'Gene': 'SNX31', 'topRSID': 'rs1693568', 'p_GWAS': 2.501442e-08, 'b_GWAS': 0.0457}, {'UUID': 'NDD_SMR_genes_all_update_text_1109774', 'Gene': 'SNX31', 'topRSID': 'rs1693568', 'p_GWAS': 2.501442e-08, 'b_GWAS': -0.0457}, {'UUID': 'NDD_SMR_genes_all_update_text_3737', 'Gene': 'SNX31', 'topRSID': 'rs1693568', 'p_GWAS': 2.501442e-08, 'b_GWAS': -0.0457}, {'UUID': 'NDD_SMR_genes_all_update_text_1716239', 'Gene': 'SNX31', 'topRSID': 'rs1693560', 'p_GWAS': 3.543857e-08, 'b_GWAS': 0.0452}, {'UUID': 'NDD_SMR_genes_all_update_text_1446284', 'Gene': 'SNX31', 'topRSID': 'rs1693560', 'p_GWAS': 3.543857e-08, 'b_GWAS': 0.0452}, {'UUID': 'NDD_SMR_genes_all_update_text_1156139', 'Gene': 'SNX31', 'topRSID': 'rs1693560', 'p_GWAS': 3.543857e-08, 'b_GWAS': 0.0452}, {'UUID': 'NDD_SMR_genes_all_update_text_1199366', 'Gene': 'SNX31', 'topRSID': 'rs2978102', 'p_GWAS': 3.543857e-08, 'b_GWAS': 0.0452}, {'UUID': 'NDD_SMR_genes_all_update_text_1479434', 'Gene': 'SNX31', 'topRSID': 'rs1693560', 'p_GWAS': 3.543857e-08, 'b_GWAS': 0.0452}, {'UUID': 'NDD_SMR_genes_all_update_text_1583347', 'Gene': 'SNX31', 'topRSID': 'rs1693560', 'p_GWAS': 3.543857e-08, 'b_GWAS': 0.0452}, {'UUID': 'NDD_SMR_genes_all_update_text_1597763', 'Gene': 'SNX31', 'topRSID': 'rs1693560', 'p_GWAS': 3.543857e-08, 'b_GWAS': 0.0452}, {'UUID': 'NDD_SMR_genes_all_update_text_1608145', 'Gene': 'SNX31', 'topRSID': 'rs1693560', 'p_GWAS': 3.543857e-08, 'b_GWAS': -0.0452}, {'UUID': 'NDD_SMR_genes_all_update_text_1453595', 'Gene': 'SNX31', 'topRSID': 'rs1693560', 'p_GWAS': 3.543857e-08, 'b_GWAS': 0.0452}]
refined
Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1733
Q10
Are there any RP11-798G7.5 SNPs that have a statistically significant association with Progressive supranuclear palsy?
Yes, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there is at least 1 RP11-798G7.5 SNP that are significantly associatied with Progressive supranuclear palsy: • rs11012 (GWAS p-value: 2.11e-42; b-value: 1.608)
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'RP11-798G7.5' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_1579414', 'Gene': 'RP11-798G7.5', 'topRSID': 'rs11012', 'p_GWAS': 2.1076899999999998e-42, 'b_GWAS': 1.6076}]
refined
Distinct, Multi-Filter, Order By
GWAS Significance
Q10.380
Q10
Are there any ANXA9 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within ANXA9 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'ANXA9' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.240
Q10
Are there any CTA-292E10.6 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within CTA-292E10.6 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'CTA-292E10.6' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.257
Q10
Are there any IHH SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within IHH that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'IHH' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1032
Q10
Are there any ZFYVE1 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within ZFYVE1 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'ZFYVE1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
refined
Distinct, Multi-Filter, Order By
GWAS Significance
Q10.30
Q10
Are there any MESP2 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within MESP2 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'MESP2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
refined
Distinct, Multi-Filter, Order By
GWAS Significance
Q10.293
Q10
Are there any SNRNP70 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within SNRNP70 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'SNRNP70' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
refined
Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1886
Q10
Are there any CTC-435M10.6 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within CTC-435M10.6 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'CTC-435M10.6' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1823
Q10
Are there any AC079779.7 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within AC079779.7 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'AC079779.7' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
refined
Distinct, Multi-Filter, Order By
GWAS Significance
Q10.620
Q10
Are there any CCDC158 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within CCDC158 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'CCDC158' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
refined
Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1667
Q10
Are there any TNNI3K SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within TNNI3K that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'TNNI3K' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
refined
Distinct, Multi-Filter, Order By
GWAS Significance
Q10.850
Q10
Are there any LIM2 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within LIM2 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'LIM2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
refined
Distinct, Multi-Filter, Order By
GWAS Significance
Q10.215
Q10
Are there any HRSP12 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within HRSP12 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'HRSP12' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
refined
Distinct, Multi-Filter, Order By
GWAS Significance
Q10.524
Q10
Are there any SPIRE1 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within SPIRE1 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'SPIRE1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
refined
Distinct, Multi-Filter, Order By
GWAS Significance
Q10.477
Q10
Are there any RP3-510D11.1 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within RP3-510D11.1 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'RP3-510D11.1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
refined
Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1327
Q10
Are there any CSTF1 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within CSTF1 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'CSTF1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
refined
Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1433
Q10
Are there any HSPB11 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within HSPB11 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'HSPB11' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
refined
Distinct, Multi-Filter, Order By
GWAS Significance
Q10.123
Q10
Are there any PRMT5 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within PRMT5 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'PRMT5' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
refined
Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1351
Q10
Are there any ANO3 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within ANO3 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'ANO3' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
refined
Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1942
Q10
Are there any SPRED3 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within SPRED3 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'SPRED3' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1371
Q10
Are there any AC104667.3 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within AC104667.3 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'AC104667.3' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.1171
Q10
Are there any AKAP12 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within AKAP12 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'AKAP12' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.138
Q10
Are there any TECPR2 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within TECPR2 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'TECPR2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.1134
Q10
Are there any HAO2 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within HAO2 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'HAO2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.1874
Q10
Are there any TAOK2 SNPs that have a statistically significant association with Alzheimer's Disease?
Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 2 TAOK2 SNPs that are significantly associatied with Alzheimer's Disease: • rs4788204 (GWAS p-value: 9.98e-10; b-value: -0.0501) • rs8054556 (GWAS p-value: 2.13e-09; b-value: 0.0491)
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'TAOK2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_1396160', 'Gene': 'TAOK2', 'topRSID': 'rs4788204', 'p_GWAS': 9.978352e-10, 'b_GWAS': -0.0501}, {'UUID': 'NDD_SMR_genes_all_update_text_1610393', 'Gene': 'TAOK2', 'topRSID': 'rs8054556', 'p_GWAS': 2.12692e-09, 'b_GWAS': 0.0491}]
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Q10.1241
Q10
Are there any G2E3 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within G2E3 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'G2E3' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1338
Q10
Are there any NELFE SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within NELFE that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'NELFE' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.958
Q10
Are there any BICC1 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within BICC1 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'BICC1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.929
Q10
Are there any SALL4P5 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within SALL4P5 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'SALL4P5' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.112
Q10
Are there any RIN3 SNPs that have a statistically significant association with Alzheimer's Disease?
Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there is at least 1 RIN3 SNP that are significantly associatied with Alzheimer's Disease: • rs17783630 (GWAS p-value: 8.56e-10; b-value: -0.0503)
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'RIN3' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_1500406', 'Gene': 'RIN3', 'topRSID': 'rs17783630', 'p_GWAS': 8.561768e-10, 'b_GWAS': -0.0503}]
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GWAS Significance
Q10.1240
Q10
Are there any SPARCL1 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within SPARCL1 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'SPARCL1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1921
Q10
Are there any LILRP2 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within LILRP2 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'LILRP2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1963
Q10
Are there any RP11-274M17.1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within RP11-274M17.1 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'RP11-274M17.1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.214
Q10
Are there any TSPAN14 SNPs that have a statistically significant association with Alzheimer's Disease?
Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 5 TSPAN14 SNPs that are significantly associatied with Alzheimer's Disease: • rs7086627 (GWAS p-value: 1.85e-09; b-value: 0.0559) • rs7098414 (GWAS p-value: 1.42e-09; b-value: 0.0563) • rs10788639 (GWAS p-value: 1.97e-09; b-value: -0.0552) • rs1993484 (GWAS p-value: 4.60e-11; b-value: -0.0632) • rs10749609 (GWAS p-value: 9.98e-14; b-value: -0.0759)
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'TSPAN14' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_1393825', 'Gene': 'TSPAN14', 'topRSID': 'rs10749609', 'p_GWAS': 9.979253e-14, 'b_GWAS': -0.0759}, {'UUID': 'NDD_SMR_genes_all_update_text_1200108', 'Gene': 'TSPAN14', 'topRSID': 'rs10749609', 'p_GWAS': 9.979253e-14, 'b_GWAS': 0.0759}, {'UUID': 'NDD_SMR_genes_all_update_text_1105563', 'Gene': 'TSPAN14', 'topRSID': 'rs10749609', 'p_GWAS': 9.979253e-14, 'b_GWAS': -0.0759}, {'UUID': 'NDD_SMR_genes_all_update_text_572650', 'Gene': 'TSPAN14', 'topRSID': 'rs1993484', 'p_GWAS': 4.600162e-11, 'b_GWAS': -0.0632}, {'UUID': 'NDD_SMR_genes_all_update_text_85785', 'Gene': 'TSPAN14', 'topRSID': 'rs7098414', 'p_GWAS': 1.415004e-09, 'b_GWAS': 0.0563}, {'UUID': 'NDD_SMR_genes_all_update_text_85783', 'Gene': 'TSPAN14', 'topRSID': 'rs7086627', 'p_GWAS': 1.846639e-09, 'b_GWAS': 0.0559}, {'UUID': 'NDD_SMR_genes_all_update_text_572649', 'Gene': 'TSPAN14', 'topRSID': 'rs10788639', 'p_GWAS': 1.973175e-09, 'b_GWAS': -0.0552}]
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Q10.999
Q10
Are there any KRTAP11-1 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within KRTAP11-1 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'KRTAP11-1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1269
Q10
Are there any CTD-3195I5.3 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within CTD-3195I5.3 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'CTD-3195I5.3' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.592
Q10
Are there any TARBP1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within TARBP1 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'TARBP1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.1391
Q10
Are there any XYLT1 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within XYLT1 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'XYLT1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1450
Q10
Are there any CFHR2 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within CFHR2 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'CFHR2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.279
Q10
Are there any PLXNA2 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within PLXNA2 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'PLXNA2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.1507
Q10
Are there any TIMD4 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within TIMD4 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'TIMD4' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.1328
Q10
Are there any SLCO1B1 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within SLCO1B1 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'SLCO1B1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.1271
Q10
Are there any RABGGTB SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within RABGGTB that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'RABGGTB' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.1820
Q10
Are there any ATN1 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within ATN1 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'ATN1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.273
Q10
Are there any ARHGAP27 SNPs that have a statistically significant association with Parkinson's Disease?
Yes, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there is at least 18 ARHGAP27 SNP that are significantly associatied with Parkinson's Disease: • rs62055544 (GWAS p-value: 1.09e-20; b-value: -0.2537) • rs112454267 (GWAS p-value: 1.30e-20; b-value: -0.2504) • rs753236 (GWAS p-value: 8.76e-20; b-value: -0.2467) • rs62064597 (GWAS p-value: 5.73e-17; b-value: 0.2168) • rs56220387 (GWAS p-value: 7.69e-17; b-value: 0.2159) • rs62064637 (GWAS p-value: 1.09e-16; b-value: 0.214) • rs62064641 (GWAS p-value: 2.37e-16; b-value: 0.2116) • rs56212100 (GWAS p-value: 2.94e-16; b-value: -0.2232) • rs35327136 (GWAS p-value: 3.84e-16; b-value: 0.2101) • rs144733372 (GWAS p-value: 4.71e-16; b-value: -0.2257)
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'ARHGAP27' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_1281347', 'Gene': 'ARHGAP27', 'topRSID': 'rs62055544', 'p_GWAS': 1.086986e-20, 'b_GWAS': -0.2537}, {'UUID': 'NDD_SMR_genes_all_update_text_948843', 'Gene': 'ARHGAP27', 'topRSID': 'rs112454267', 'p_GWAS': 1.295891e-20, 'b_GWAS': -0.2504}, {'UUID': 'NDD_SMR_genes_all_update_text_948842', 'Gene': 'ARHGAP27', 'topRSID': 'rs112454267', 'p_GWAS': 1.295891e-20, 'b_GWAS': -0.2504}, {'UUID': 'NDD_SMR_genes_all_update_text_1730056', 'Gene': 'ARHGAP27', 'topRSID': 'rs753236', 'p_GWAS': 8.761099e-20, 'b_GWAS': -0.2467}, {'UUID': 'NDD_SMR_genes_all_update_text_491048', 'Gene': 'ARHGAP27', 'topRSID': 'rs62064597', 'p_GWAS': 5.729817000000001e-17, 'b_GWAS': 0.2168}, {'UUID': 'NDD_SMR_genes_all_update_text_491053', 'Gene': 'ARHGAP27', 'topRSID': 'rs56220387', 'p_GWAS': 7.690613000000001e-17, 'b_GWAS': 0.2159}, {'UUID': 'NDD_SMR_genes_all_update_text_491054', 'Gene': 'ARHGAP27', 'topRSID': 'rs56220387', 'p_GWAS': 7.690613000000001e-17, 'b_GWAS': 0.2159}, {'UUID': 'NDD_SMR_genes_all_update_text_491052', 'Gene': 'ARHGAP27', 'topRSID': 'rs56220387', 'p_GWAS': 7.690613000000001e-17, 'b_GWAS': 0.2159}, {'UUID': 'NDD_SMR_genes_all_update_text_491050', 'Gene': 'ARHGAP27', 'topRSID': 'rs56220387', 'p_GWAS': 7.690613000000001e-17, 'b_GWAS': 0.2159}, {'UUID': 'NDD_SMR_genes_all_update_text_491051', 'Gene': 'ARHGAP27', 'topRSID': 'rs56220387', 'p_GWAS': 7.690613000000001e-17, 'b_GWAS': 0.2159}, {'UUID': 'NDD_SMR_genes_all_update_text_491055', 'Gene': 'ARHGAP27', 'topRSID': 'rs62064637', 'p_GWAS': 1.089753e-16, 'b_GWAS': 0.214}, {'UUID': 'NDD_SMR_genes_all_update_text_491069', 'Gene': 'ARHGAP27', 'topRSID': 'rs62064641', 'p_GWAS': 2.373064e-16, 'b_GWAS': 0.2116}, {'UUID': 'NDD_SMR_genes_all_update_text_491070', 'Gene': 'ARHGAP27', 'topRSID': 'rs62064641', 'p_GWAS': 2.373064e-16, 'b_GWAS': 0.2116}, {'UUID': 'NDD_SMR_genes_all_update_text_491065', 'Gene': 'ARHGAP27', 'topRSID': 'rs62064641', 'p_GWAS': 2.373064e-16, 'b_GWAS': 0.2116}, {'UUID': 'NDD_SMR_genes_all_update_text_491056', 'Gene': 'ARHGAP27', 'topRSID': 'rs56212100', 'p_GWAS': 2.938502e-16, 'b_GWAS': -0.2232}, {'UUID': 'NDD_SMR_genes_all_update_text_491063', 'Gene': 'ARHGAP27', 'topRSID': 'rs35327136', 'p_GWAS': 3.842955e-16, 'b_GWAS': 0.2101}, {'UUID': 'NDD_SMR_genes_all_update_text_948851', 'Gene': 'ARHGAP27', 'topRSID': 'rs144733372', 'p_GWAS': 4.711841e-16, 'b_GWAS': -0.2257}, {'UUID': 'NDD_SMR_genes_all_update_text_491057', 'Gene': 'ARHGAP27', 'topRSID': 'rs62065376', 'p_GWAS': 4.949608e-16, 'b_GWAS': -0.2231}, {'UUID': 'NDD_SMR_genes_all_update_text_948852', 'Gene': 'ARHGAP27', 'topRSID': 'rs11012', 'p_GWAS': 5.254869e-16, 'b_GWAS': -0.2229}, {'UUID': 'NDD_SMR_genes_all_update_text_1262217', 'Gene': 'ARHGAP27', 'topRSID': 'rs111423688', 'p_GWAS': 5.271409e-16, 'b_GWAS': -0.2237}, {'UUID': 'NDD_SMR_genes_all_update_text_948844', 'Gene': 'ARHGAP27', 'topRSID': 'rs34465449', 'p_GWAS': 5.747858e-16, 'b_GWAS': -0.2226}, {'UUID': 'NDD_SMR_genes_all_update_text_948846', 'Gene': 'ARHGAP27', 'topRSID': 'rs35489312', 'p_GWAS': 5.922104e-16, 'b_GWAS': -0.2225}, {'UUID': 'NDD_SMR_genes_all_update_text_948845', 'Gene': 'ARHGAP27', 'topRSID': 'rs35489312', 'p_GWAS': 5.922104e-16, 'b_GWAS': -0.2225}, {'UUID': 'NDD_SMR_genes_all_update_text_491068', 'Gene': 'ARHGAP27', 'topRSID': 'rs62065379', 'p_GWAS': 6.101554e-16, 'b_GWAS': -0.2224}, {'UUID': 'NDD_SMR_genes_all_update_text_491064', 'Gene': 'ARHGAP27', 'topRSID': 'rs62065379', 'p_GWAS': 6.101554e-16, 'b_GWAS': -0.2224}, {'UUID': 'NDD_SMR_genes_all_update_text_491066', 'Gene': 'ARHGAP27', 'topRSID': 'rs62065379', 'p_GWAS': 6.101554e-16, 'b_GWAS': -0.2224}, {'UUID': 'NDD_SMR_genes_all_update_text_491067', 'Gene': 'ARHGAP27', 'topRSID': 'rs113575082', 'p_GWAS': 6.286359e-16, 'b_GWAS': -0.2223}, {'UUID': 'NDD_SMR_genes_all_update_text_1435912', 'Gene': 'ARHGAP27', 'topRSID': 'rs62065378', 'p_GWAS': 6.67267e-16, 'b_GWAS': -0.2221}]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1863
Q10
Are there any CLEC12B SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within CLEC12B that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'CLEC12B' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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GWAS Significance
Q10.578
Q10
Are there any JMJD8 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within JMJD8 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'JMJD8' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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GWAS Significance
Q10.638
Q10
Are there any RP11-531H8.1 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within RP11-531H8.1 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'RP11-531H8.1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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GWAS Significance
Q10.713
Q10
Are there any H2AC4 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within H2AC4 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'H2AC4' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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GWAS Significance
Q10.1529
Q10
Are there any RPS26P8 SNPs that have a statistically significant association with Parkinson's Disease?
Yes, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are at least 2 RPS26P8 SNPs that are significantly associatied with Parkinson's Disease: • rs566238830 (GWAS p-value: 5.28e-19; b-value: -0.2467) • rs55974014 (GWAS p-value: 8.84e-21; b-value: -0.2571)
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'RPS26P8' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_1328929', 'Gene': 'RPS26P8', 'topRSID': 'rs55974014', 'p_GWAS': 8.840428e-21, 'b_GWAS': -0.2571}, {'UUID': 'NDD_SMR_genes_all_update_text_1242268', 'Gene': 'RPS26P8', 'topRSID': 'rs566238830', 'p_GWAS': 5.284153e-19, 'b_GWAS': -0.2467}]
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GWAS Significance
Q10.627
Q10
Are there any RP11-274B21.1 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within RP11-274B21.1 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'RP11-274B21.1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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GWAS Significance
Q10.1991
Q10
Are there any APOC4 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within APOC4 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'APOC4' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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GWAS Significance
Q10.813
Q10
Are there any RP11-73G16.3 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within RP11-73G16.3 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'RP11-73G16.3' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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GWAS Significance
Q10.309
Q10
Are there any SNX29 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within SNX29 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'SNX29' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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GWAS Significance
Q10.550
Q10
Are there any RP11-385F7.1 SNPs that have a statistically significant association with Alzheimer's Disease?
Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 6 RP11-385F7.1 SNPs that are significantly associatied with Alzheimer's Disease: • rs4715019 (GWAS p-value: 5.16e-12; b-value: 0.0628) • rs1931837 (GWAS p-value: 6.02e-12; b-value: 0.0626) • rs9369717 (GWAS p-value: 3.23e-12; b-value: 0.0641) • rs12195738 (GWAS p-value: 1.60e-12; b-value: 0.065) • rs9473119 (GWAS p-value: 5.57e-12; b-value: 0.0627) • rs9381564 (GWAS p-value: 6.50e-12; b-value: 0.0625)
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'RP11-385F7.1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_1287260', 'Gene': 'RP11-385F7.1', 'topRSID': 'rs12195738', 'p_GWAS': 1.603647e-12, 'b_GWAS': 0.065}, {'UUID': 'NDD_SMR_genes_all_update_text_1172618', 'Gene': 'RP11-385F7.1', 'topRSID': 'rs9369717', 'p_GWAS': 3.228717e-12, 'b_GWAS': 0.0641}, {'UUID': 'NDD_SMR_genes_all_update_text_67372', 'Gene': 'RP11-385F7.1', 'topRSID': 'rs4715019', 'p_GWAS': 5.160179e-12, 'b_GWAS': 0.0628}, {'UUID': 'NDD_SMR_genes_all_update_text_1607354', 'Gene': 'RP11-385F7.1', 'topRSID': 'rs9473119', 'p_GWAS': 5.574931e-12, 'b_GWAS': 0.0627}, {'UUID': 'NDD_SMR_genes_all_update_text_622987', 'Gene': 'RP11-385F7.1', 'topRSID': 'rs1931837', 'p_GWAS': 6.022304e-12, 'b_GWAS': 0.0626}, {'UUID': 'NDD_SMR_genes_all_update_text_1687622', 'Gene': 'RP11-385F7.1', 'topRSID': 'rs9381564', 'p_GWAS': 6.504808e-12, 'b_GWAS': 0.0625}]
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GWAS Significance
Q10.1606
Q10
Are there any STAG3L5P-PVRIG2P-PILRB SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within STAG3L5P-PVRIG2P-PILRB that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'STAG3L5P-PVRIG2P-PILRB' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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GWAS Significance
Q10.1743
Q10
Are there any F12 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within F12 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'F12' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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GWAS Significance
Q10.50
Q10
Are there any CYP2A7 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within CYP2A7 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'CYP2A7' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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GWAS Significance
Q10.1089
Q10
Are there any CASC16 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within CASC16 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'CASC16' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.1674
Q10
Are there any RP11-438F14.3 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within RP11-438F14.3 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'RP11-438F14.3' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.1697
Q10
Are there any MME SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within MME that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'MME' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance