uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
values | bio_category stringclasses 14
values |
|---|---|---|---|---|---|---|---|---|
Q1.986 | Q1 | Is NOS1 a druggable gene? | There are currently no approved drugs targeting NOS1, but there are 2 drugs in clinical trials indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%NOS1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_890', 'drugName': 'Tilarginine', 'drugIsApproved': False, 'newLinkedTargets_string': 'NOS1 (ENSG00000089250), NOS2 (ENSG00000007171), NOS3 (ENSG00000164867)', 'maxClinicalTrialPhase': 3}, {'UUID': 'DrugGeneTargets_v2_1662', 'drugName': 'Tilarginine Acetate', 'drugIsApproved': False, 'newLi... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1507 | Q1 | Is TUBB6 a druggable gene? | There are currently 20 approved drugs which target TUBB6, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%TUBB6 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1084', 'drugName': 'Brentuximab Vedotin', 'drugIsApproved': True, 'newLinkedTargets_string': 'TNFRSF8 (ENSG00000120949), TUBB4B (ENSG00000188229), TUBB1 (ENSG00000101162), TUBA3C (ENSG00000198033), TUBA4A (ENSG00000127824), TUBB3 (ENSG00000258947), TUBA1A (ENSG00000167552), TUBB4A (ENSG000... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.192 | Q1 | Is CCND1 a druggable gene? | There is 1 drug, Palbociclib, that targets CCND1, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%CCND1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_2461', 'drugName': 'Palbociclib', 'drugIsApproved': True, 'newLinkedTargets_string': 'CCND1 (ENSG00000110092), CDK6 (ENSG00000105810), CDK4 (ENSG00000135446)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_2460', 'drugName': 'Palbociclib', 'drugIsApproved': True, 'newLinkedTarg... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1147 | Q1 | Is PSCA a druggable gene? | There are currently no approved drugs targeting PSCA, but there is 1 drug in a clinical trial indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%PSCA %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_5916', 'drugName': 'Mk-4721', 'drugIsApproved': False, 'newLinkedTargets_string': 'PSCA (ENSG00000167653)', 'maxClinicalTrialPhase': 2}] | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.998 | Q1 | Is NPR1 a druggable gene? | There is 1 drug, Nesiritide, that targets NPR1, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%NPR1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_3389', 'drugName': 'Nesiritide', 'drugIsApproved': True, 'newLinkedTargets_string': 'NPR1 (ENSG00000169418)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_2532', 'drugName': 'Carperitide', 'drugIsApproved': False, 'newLinkedTargets_string': 'NPR2 (ENSG00000159899), NPR1 (ENSG0... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1500 | Q1 | Is TUBB a druggable gene? | There are currently 20 approved drugs which target TUBB, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%TUBB %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1084', 'drugName': 'Brentuximab Vedotin', 'drugIsApproved': True, 'newLinkedTargets_string': 'TNFRSF8 (ENSG00000120949), TUBB4B (ENSG00000188229), TUBB1 (ENSG00000101162), TUBA3C (ENSG00000198033), TUBA4A (ENSG00000127824), TUBB3 (ENSG00000258947), TUBA1A (ENSG00000167552), TUBB4A (ENSG000... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1283 | Q1 | Is RPS18 a druggable gene? | There is 1 drug, Ataluren, that targets RPS18, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%RPS18 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_3776', 'drugName': 'Ataluren', 'drugIsApproved': True, 'newLinkedTargets_string': 'RPSA (ENSG00000168028), RPS27 (ENSG00000177954), RPS6 (ENSG00000137154), RPS2 (ENSG00000140988), RPS3 (ENSG00000149273), RPS3A (ENSG00000145425), RPS4X (ENSG00000198034), RPS4Y1 (ENSG00000129824), RPS5 (ENSG... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.610 | Q1 | Is HSP90AB1 a druggable gene? | There are currently no approved drugs targeting HSP90AB1, but there are 10 drugs in clinical trials indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%HSP90AB1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1279', 'drugName': 'Retaspimycin Hydrochloride', 'drugIsApproved': False, 'newLinkedTargets_string': 'HSP90AA1 (ENSG00000080824), HSP90AB1 (ENSG00000096384)', 'maxClinicalTrialPhase': 3}, {'UUID': 'DrugGeneTargets_v2_2657', 'drugName': 'Tanespimycin', 'drugIsApproved': False, 'newLinkedTar... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.182 | Q1 | Is CASP7 a druggable gene? | There are currently no approved drugs targeting CASP7, but there is 1 drug in a clinical trial indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%CASP7 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_45', 'drugName': 'Emricasan', 'drugIsApproved': False, 'newLinkedTargets_string': 'CASP4 (ENSG00000196954), CASP9 (ENSG00000132906), CASP3 (ENSG00000164305), CASP5 (ENSG00000137757), CASP6 (ENSG00000138794), CASP7 (ENSG00000165806), CASP8 (ENSG00000064012), CASP1 (ENSG00000137752), CASP2 (... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.303 | Q1 | Is COL5A2 a druggable gene? | There are currently 2 approved drugs which target COL5A2, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%COL5A2 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_5818', 'drugName': 'Ocriplasmin', 'drugIsApproved': True, 'newLinkedTargets_string': 'FN1 (ENSG00000115414), COL1A2 (ENSG00000164692), COL1A1 (ENSG00000108821), COL2A1 (ENSG00000139219), COL3A1 (ENSG00000168542), COL4A1 (ENSG00000187498), COL5A1 (ENSG00000130635), COL6A1 (ENSG00000142156),... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.499 | Q1 | Is GABRB1 a druggable gene? | There are currently 70 approved drugs which target GABRB1, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%GABRB1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_3142', 'drugName': 'Lorazepam', 'drugIsApproved': True, 'newLinkedTargets_string': 'GABRA1 (ENSG00000022355), GABRB2 (ENSG00000145864), GABRG2 (ENSG00000113327), GABRB3 (ENSG00000166206), GABRA4 (ENSG00000109158), GABRG3 (ENSG00000182256), GABRQ (ENSG00000268089), GABRA3 (ENSG00000011677),... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1324 | Q1 | Is RYR3 a druggable gene? | There are currently 2 approved drugs which target RYR3, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%RYR3 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_4505', 'drugName': 'Dantrolene Sodium', 'drugIsApproved': True, 'newLinkedTargets_string': 'RYR3 (ENSG00000198838), RYR1 (ENSG00000196218)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_4504', 'drugName': 'Dantrolene Sodium', 'drugIsApproved': True, 'newLinkedTargets_string': ... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1288 | Q1 | Is RPS23 a druggable gene? | There is 1 drug, Ataluren, that targets RPS23, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%RPS23 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_3776', 'drugName': 'Ataluren', 'drugIsApproved': True, 'newLinkedTargets_string': 'RPSA (ENSG00000168028), RPS27 (ENSG00000177954), RPS6 (ENSG00000137154), RPS2 (ENSG00000140988), RPS3 (ENSG00000149273), RPS3A (ENSG00000145425), RPS4X (ENSG00000198034), RPS4Y1 (ENSG00000129824), RPS5 (ENSG... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1268 | Q1 | Is RPL7 a druggable gene? | There is 1 drug, Ataluren, that targets RPL7, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%RPL7 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_3776', 'drugName': 'Ataluren', 'drugIsApproved': True, 'newLinkedTargets_string': 'RPSA (ENSG00000168028), RPS27 (ENSG00000177954), RPS6 (ENSG00000137154), RPS2 (ENSG00000140988), RPS3 (ENSG00000149273), RPS3A (ENSG00000145425), RPS4X (ENSG00000198034), RPS4Y1 (ENSG00000129824), RPS5 (ENSG... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.520 | Q1 | Is GIPR a druggable gene? | There is 1 drug, Tirzepatide, that targets GIPR, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%GIPR %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_5134', 'drugName': 'Tirzepatide', 'drugIsApproved': True, 'newLinkedTargets_string': 'GIPR (ENSG00000010310), GLP1R (ENSG00000112164)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_5135', 'drugName': 'Tirzepatide', 'drugIsApproved': True, 'newLinkedTargets_string': 'GIPR (ENSG... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1075 | Q1 | Is PIK3CA a druggable gene? | There are currently 3 approved drugs which target PIK3CA, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%PIK3CA %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_722', 'drugName': 'Alpelisib', 'drugIsApproved': True, 'newLinkedTargets_string': 'PIK3CA (ENSG00000121879)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_1214', 'drugName': 'Copanlisib Hydrochloride', 'drugIsApproved': True, 'newLinkedTargets_string': 'PIK3CA (ENSG00000121879... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.478 | Q1 | Is FOLH1 a druggable gene? | There are currently 2 approved drugs which target FOLH1, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%FOLH1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_5876', 'drugName': 'Lutetium Lu 177 Vipivotide Tetraxetan', 'drugIsApproved': True, 'newLinkedTargets_string': 'FOLH1 (ENSG00000086205)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_5373', 'drugName': 'Vipivotide Tetraxetan Lutetium', 'drugIsApproved': True, 'newLinkedTargets... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.159 | Q1 | Is CACNB4 a druggable gene? | There are currently 9 approved drugs which target CACNB4, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%CACNB4 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_142', 'drugName': 'Gabapentin', 'drugIsApproved': True, 'newLinkedTargets_string': 'CACNA1H (ENSG00000196557), CACNA2D1 (ENSG00000153956), CACNA1C (ENSG00000151067), CACNA2D3 (ENSG00000157445), CACNA1S (ENSG00000081248), CACNA2D2 (ENSG00000007402), CACNA1D (ENSG00000157388), CACNA1A (ENSG0... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1204 | Q1 | Is PTPN11 a druggable gene? | There are currently no approved drugs targeting PTPN11, but there is 1 drug in a clinical trial indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%PTPN11 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_6363', 'drugName': 'Batoprotafib', 'drugIsApproved': False, 'newLinkedTargets_string': 'PTPN11 (ENSG00000179295)', 'maxClinicalTrialPhase': 1}] | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.17 | Q1 | Is ADA a druggable gene? | There is 1 drug, Pentostatin, that targets ADA, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%ADA %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_251', 'drugName': 'Pentostatin', 'drugIsApproved': True, 'newLinkedTargets_string': 'ADA (ENSG00000196839)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_5186', 'drugName': 'Coformycin', 'drugIsApproved': False, 'newLinkedTargets_string': 'ADA (ENSG00000196839)', 'maxClinicalT... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1078 | Q1 | Is PIK3CG a druggable gene? | There is 1 drug, Duvelisib, that targets PIK3CG, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%PIK3CG %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1892', 'drugName': 'Duvelisib', 'drugIsApproved': True, 'newLinkedTargets_string': 'PIK3CG (ENSG00000105851), PIK3CD (ENSG00000171608)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_1893', 'drugName': 'Duvelisib', 'drugIsApproved': True, 'newLinkedTargets_string': 'PIK3CG (ENS... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q10.589 | Q10 | Are there any PCAT6 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within PCAT6 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'PCAT6' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1868 | Q10 | Are there any SCN3A SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within SCN3A that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'SCN3A' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1061 | Q10 | Are there any PPP3R1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within PPP3R1 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'PPP3R1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1084 | Q10 | Are there any TNPO2 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within TNPO2 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'TNPO2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.925 | Q10 | Are there any RP11-259G18.2 SNPs that have a statistically significant association with Parkinson's Disease? | Yes, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there is at least 14 RP11-259G18.2 SNP that are significantly associatied with Parkinson's Disease:
• rs17661015 (GWAS p-value: 4.30e-21; b-value: -0.2573)
• rs9468 (GWAS p-value: 5.02e-21; b-value: -0.2371)
• ... | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'RP11-259G18.2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1679567', 'Gene': 'RP11-259G18.2', 'topRSID': 'rs17661015', 'p_GWAS': 4.3048099999999995e-21, 'b_GWAS': -0.2573}, {'UUID': 'NDD_SMR_genes_all_update_text_1451664', 'Gene': 'RP11-259G18.2', 'topRSID': 'rs9468', 'p_GWAS': 5.021668e-21, 'b_GWAS': -0.2371}, {'UUID': 'NDD_SMR_genes_a... | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.73 | Q10 | Are there any AC106801.1 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within AC106801.1 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'AC106801.1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.435 | Q10 | Are there any TENC1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within TENC1 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'TENC1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.911 | Q10 | Are there any CATSPERB SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within CATSPERB that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'CATSPERB' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.922 | Q10 | Are there any TSC2 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within TSC2 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'TSC2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1679 | Q10 | Are there any AC006262.6 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within AC006262.6 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'AC006262.6' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1272 | Q10 | Are there any SLC45A3 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within SLC45A3 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'SLC45A3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1094 | Q10 | Are there any APOC1P1 SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there is at least 1 APOC1P1 SNP that are significantly associatied with Alzheimer's Disease:
• rs5112 (GWAS p-value: 1.03e-24; b-value: -0.0975) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'APOC1P1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1466878', 'Gene': 'APOC1P1', 'topRSID': 'rs5112', 'p_GWAS': 1.032731e-24, 'b_GWAS': -0.0975}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.389 | Q10 | Are there any MAT1A SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 5 MAT1A SNPs that are significantly associatied with Alzheimer's Disease:
• rs10749551 (GWAS p-value: 6.54e-09; b-value: 0.0499)
• rs10788545 (GWAS p-value: 2.91e-08; b-value: 0.0477)
• rs18905... | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'MAT1A' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_85765', 'Gene': 'MAT1A', 'topRSID': 'rs10749551', 'p_GWAS': 6.540141e-09, 'b_GWAS': 0.0499}, {'UUID': 'NDD_SMR_genes_all_update_text_85768', 'Gene': 'MAT1A', 'topRSID': 'rs9420359', 'p_GWAS': 8.622531e-09, 'b_GWAS': 0.0495}, {'UUID': 'NDD_SMR_genes_all_update_text_572621', 'Gene... | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.841 | Q10 | Are there any RP11-293E1.1 SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there is at least 1 RP11-293E1.1 SNP that are significantly associatied with Alzheimer's Disease:
• rs62062286 (GWAS p-value: 2.12e-08; b-value: -0.0549) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RP11-293E1.1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1203005', 'Gene': 'RP11-293E1.1', 'topRSID': 'rs62062286', 'p_GWAS': 2.118427e-08, 'b_GWAS': -0.0549}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.774 | Q10 | Are there any SBF2 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within SBF2 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'SBF2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1805 | Q10 | Are there any GAD1 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within GAD1 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'GAD1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1992 | Q10 | Are there any CLASRP SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there is at least 1 CLASRP SNP that are significantly associatied with Alzheimer's Disease:
• rs1560725 (GWAS p-value: 1.31e-08; b-value: 0.0506) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'CLASRP' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_122474', 'Gene': 'CLASRP', 'topRSID': 'rs1560725', 'p_GWAS': 1.30512e-08, 'b_GWAS': 0.0506}, {'UUID': 'NDD_SMR_genes_all_update_text_637443', 'Gene': 'CLASRP', 'topRSID': 'rs1560725', 'p_GWAS': 1.30512e-08, 'b_GWAS': 0.0506}, {'UUID': 'NDD_SMR_genes_all_update_text_1503909', 'Ge... | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1066 | Q10 | Are there any PPM1B SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within PPM1B that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'PPM1B' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.58 | Q10 | Are there any MYOM2 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within MYOM2 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'MYOM2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1688 | Q10 | Are there any WRN SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within WRN that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'WRN' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1955 | Q10 | Are there any SLC6A19 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within SLC6A19 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'SLC6A19' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1218 | Q10 | Are there any ZNF187 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within ZNF187 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'ZNF187' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1680 | Q10 | Are there any RP11-573D15.2 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within RP11-573D15.2 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'RP11-573D15.2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1975 | Q10 | Are there any CTD-2009A10.1 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within CTD-2009A10.1 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'CTD-2009A10.1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.213 | Q10 | Are there any SLC6A11 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within SLC6A11 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'SLC6A11' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1534 | Q10 | Are there any NFKB2 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within NFKB2 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'NFKB2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1135 | Q10 | Are there any FAM181B SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within FAM181B that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'FAM181B' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.131 | Q10 | Are there any GUSB SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within GUSB that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'GUSB' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.819 | Q10 | Are there any BZRAP1-AS1 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within BZRAP1-AS1 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'BZRAP1-AS1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1282 | Q10 | Are there any SMIM15 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within SMIM15 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'SMIM15' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1872 | Q10 | Are there any ARID3B SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within ARID3B that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'ARID3B' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.438 | Q10 | Are there any SPPL2C SNPs that have a statistically significant association with Progressive supranuclear palsy? | Yes, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are at least 2 SPPL2C SNPs that are significantly associatied with Progressive supranuclear palsy:
• rs393152 (GWAS p-value: 8.30e-51; b-value: -1.652)
• rs1981997 (GWAS p-value: 1.79e-51; b-value: 1.715) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'SPPL2C' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1194215', 'Gene': 'SPPL2C', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1714154', 'Gene': 'SPPL2C', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_22216', '... | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.417 | Q10 | Are there any SASH1 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within SASH1 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'SASH1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1504 | Q10 | Are there any RP1-41P2.7 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within RP1-41P2.7 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'RP1-41P2.7' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.234 | Q10 | Are there any C1orf97 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within C1orf97 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'C1orf97' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1708 | Q10 | Are there any UCP1 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within UCP1 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'UCP1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.895 | Q10 | Are there any FLT1 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within FLT1 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'FLT1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1625 | Q10 | Are there any NOS1AP SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within NOS1AP that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'NOS1AP' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.699 | Q10 | Are there any CCDC148 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within CCDC148 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'CCDC148' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1769 | Q10 | Are there any AL035610.1 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within AL035610.1 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'AL035610.1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.301 | Q10 | Are there any MS4A3 SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 4 MS4A3 SNPs that are significantly associatied with Alzheimer's Disease:
• rs554311 (GWAS p-value: 1.16e-12; b-value: 0.0647)
• rs539360 (GWAS p-value: 3.00e-12; b-value: -0.0628)
• rs471457 (... | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'MS4A3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_91388', 'Gene': 'MS4A3', 'topRSID': 'rs554311', 'p_GWAS': 1.161354e-12, 'b_GWAS': 0.0647}, {'UUID': 'NDD_SMR_genes_all_update_text_608692', 'Gene': 'MS4A3', 'topRSID': 'rs1286162', 'p_GWAS': 1.719125e-12, 'b_GWAS': -0.0635}, {'UUID': 'NDD_SMR_genes_all_update_text_608691', 'Gene... | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1399 | Q10 | Are there any MGEA5 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within MGEA5 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'MGEA5' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1987 | Q10 | Are there any URAHP SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within URAHP that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'URAHP' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.102 | Q10 | Are there any ATF4P4 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within ATF4P4 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'ATF4P4' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.831 | Q10 | Are there any RP11-6N17.9 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within RP11-6N17.9 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'RP11-6N17.9' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.359 | Q10 | Are there any LOC389332 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within LOC389332 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'LOC389332' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.114 | Q10 | Are there any FAM213A SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 2 FAM213A SNPs that are significantly associatied with Alzheimer's Disease:
• rs1870142 (GWAS p-value: 1.12e-08; b-value: 0.0514)
• rs4258322 (GWAS p-value: 1.28e-08; b-value: -0.0512) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'FAM213A' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_85777', 'Gene': 'FAM213A', 'topRSID': 'rs1870142', 'p_GWAS': 1.122409e-08, 'b_GWAS': 0.0514}, {'UUID': 'NDD_SMR_genes_all_update_text_572642', 'Gene': 'FAM213A', 'topRSID': 'rs4258322', 'p_GWAS': 1.278686e-08, 'b_GWAS': -0.0512}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1440 | Q10 | Are there any NIPAL2 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within NIPAL2 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'NIPAL2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1840 | Q10 | Are there any ZNF611 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within ZNF611 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'ZNF611' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.952 | Q10 | Are there any C6orf165 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within C6orf165 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'C6orf165' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1186 | Q10 | Are there any ATF6 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within ATF6 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'ATF6' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.456 | Q10 | Are there any SERPINF2 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within SERPINF2 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'SERPINF2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.876 | Q10 | Are there any EPHA1-AS1 SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 4 EPHA1-AS1 SNPs that are significantly associatied with Alzheimer's Disease:
• rs10226151 (GWAS p-value: 9.29e-12; b-value: 0.0559)
• rs75045569 (GWAS p-value: 2.73e-11; b-value: -0.0726)
• rs... | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'EPHA1-AS1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1287997', 'Gene': 'EPHA1-AS1', 'topRSID': 'rs11769559', 'p_GWAS': 2.922788e-16, 'b_GWAS': -0.0695}, {'UUID': 'NDD_SMR_genes_all_update_text_1649764', 'Gene': 'EPHA1-AS1', 'topRSID': 'rs11769559', 'p_GWAS': 2.922788e-16, 'b_GWAS': -0.0695}, {'UUID': 'NDD_SMR_genes_all_update_text... | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1545 | Q10 | Are there any NDFIP1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within NDFIP1 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'NDFIP1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1701 | Q10 | Are there any AC008731.1 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within AC008731.1 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'AC008731.1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1436 | Q10 | Are there any MED13 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within MED13 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'MED13' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.915 | Q10 | Are there any PPP1R9B SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within PPP1R9B that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'PPP1R9B' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.310 | Q10 | Are there any OVCH2 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within OVCH2 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'OVCH2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1257 | Q10 | Are there any SEPT7P2 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within SEPT7P2 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'SEPT7P2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1409 | Q10 | Are there any SLC13A5 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within SLC13A5 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'SLC13A5' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.618 | Q10 | Are there any LMO1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within LMO1 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'LMO1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1479 | Q10 | Are there any RP1-40E16.11 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within RP1-40E16.11 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'RP1-40E16.11' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.250 | Q10 | Are there any TIAM2 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within TIAM2 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'TIAM2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.734 | Q10 | Are there any EEF1E1-BLOC1S5 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within EEF1E1-BLOC1S5 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'EEF1E1-BLOC1S5' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.311 | Q10 | Are there any NRL SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within NRL that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'NRL' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.236 | Q10 | Are there any ZNF3 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within ZNF3 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'ZNF3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.72 | Q10 | Are there any ULK4 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within ULK4 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'ULK4' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.896 | Q10 | Are there any SMPD4 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within SMPD4 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'SMPD4' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1754 | Q10 | Are there any HOXA-AS4 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within HOXA-AS4 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'HOXA-AS4' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.712 | Q10 | Are there any RP11-712L6.7 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within RP11-712L6.7 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'RP11-712L6.7' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1383 | Q10 | Are there any RP5-865N13.2 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within RP5-865N13.2 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RP5-865N13.2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1329 | Q10 | Are there any AK4P3 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within AK4P3 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'AK4P3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.624 | Q10 | Are there any RP11-281O15.4 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within RP11-281O15.4 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'RP11-281O15.4' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1464 | Q10 | Are there any SETD1A SNPs that have a statistically significant association with Parkinson's Disease? | Yes, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are at least 4 SETD1A SNPs that are significantly associatied with Parkinson's Disease:
• rs11150601 (GWAS p-value: 9.34e-10; b-value: -0.112)
• rs7200879 (GWAS p-value: 2.09e-09; b-value: -0.124)
• rs129... | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'SETD1A' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1435341', 'Gene': 'SETD1A', 'topRSID': 'rs12934900', 'p_GWAS': 4.022109e-11, 'b_GWAS': -0.1215}, {'UUID': 'NDD_SMR_genes_all_update_text_1563807', 'Gene': 'SETD1A', 'topRSID': 'rs7206511', 'p_GWAS': 2.107978e-10, 'b_GWAS': -0.1169}, {'UUID': 'NDD_SMR_genes_all_update_text_485446... | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1556 | Q10 | Are there any PRR14 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within PRR14 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'PRR14' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.708 | Q10 | Are there any ATP23 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within ATP23 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'ATP23' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1928 | Q10 | Are there any AC012363.7 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within AC012363.7 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'AC012363.7' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.614 | Q10 | Are there any C17orf105 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within C17orf105 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'C17orf105' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.372 | Q10 | Are there any CTC-524C5.5 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within CTC-524C5.5 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'CTC-524C5.5' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
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