uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
values | bio_category stringclasses 14
values |
|---|---|---|---|---|---|---|---|---|
Q1.1235 | Q1 | Is RPL14 a druggable gene? | There is 1 drug, Ataluren, that targets RPL14, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%RPL14 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_3776', 'drugName': 'Ataluren', 'drugIsApproved': True, 'newLinkedTargets_string': 'RPSA (ENSG00000168028), RPS27 (ENSG00000177954), RPS6 (ENSG00000137154), RPS2 (ENSG00000140988), RPS3 (ENSG00000149273), RPS3A (ENSG00000145425), RPS4X (ENSG00000198034), RPS4Y1 (ENSG00000129824), RPS5 (ENSG... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1017 | Q1 | Is ODC1 a druggable gene? | There are currently 2 approved drugs which target ODC1, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%ODC1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1880', 'drugName': 'Eflornithine Hydrochloride', 'drugIsApproved': True, 'newLinkedTargets_string': 'ODC1 (ENSG00000115758)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_6018', 'drugName': 'Eflornithine', 'drugIsApproved': True, 'newLinkedTargets_string': 'ODC1 (ENSG000001157... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1495 | Q1 | Is TUBA1B a druggable gene? | There are currently 20 approved drugs which target TUBA1B, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%TUBA1B %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_3175', 'drugName': 'Eribulin Mesylate', 'drugIsApproved': True, 'newLinkedTargets_string': 'TUBB4B (ENSG00000188229), TUBB1 (ENSG00000101162), TUBA3C (ENSG00000198033), TUBA4A (ENSG00000127824), TUBB3 (ENSG00000258947), TUBA1A (ENSG00000167552), TUBB4A (ENSG00000104833), TUBB8 (ENSG0000026... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.95 | Q1 | Is AURKC a druggable gene? | There are currently no approved drugs targeting AURKC, but there are 10 drugs in clinical trials indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%AURKC %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1569', 'drugName': 'Danusertib', 'drugIsApproved': False, 'newLinkedTargets_string': 'AURKB (ENSG00000178999), AURKC (ENSG00000105146), AURKA (ENSG00000087586)', 'maxClinicalTrialPhase': 2}, {'UUID': 'DrugGeneTargets_v2_1177', 'drugName': 'Ilorasertib', 'drugIsApproved': False, 'newLinkedT... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1014 | Q1 | Is NTRK2 a druggable gene? | There are currently 4 approved drugs which target NTRK2, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%NTRK2 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_894', 'drugName': 'Larotrectinib', 'drugIsApproved': True, 'newLinkedTargets_string': 'NTRK1 (ENSG00000198400), NTRK2 (ENSG00000148053), NTRK3 (ENSG00000140538)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_3786', 'drugName': 'Cenegermin', 'drugIsApproved': True, 'newLinkedTa... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1076 | Q1 | Is PIK3CB a druggable gene? | There are currently no approved drugs targeting PIK3CB, but there are 31 drugs in clinical trials indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%PIK3CB %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_4060', 'drugName': 'Taselisib', 'drugIsApproved': False, 'newLinkedTargets_string': 'PIK3R1 (ENSG00000145675), PIK3CB (ENSG00000051382), PIK3CG (ENSG00000105851), PIK3CA (ENSG00000121879), PIK3R2 (ENSG00000105647), PIK3CD (ENSG00000171608), PIK3R5 (ENSG00000141506), PIK3R3 (ENSG00000117461... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1100 | Q1 | Is POLA1 a druggable gene? | There are currently 5 approved drugs which target POLA1, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%POLA1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_4', 'drugName': 'Gemcitabine Hydrochloride', 'drugIsApproved': True, 'newLinkedTargets_string': 'POLA1 (ENSG00000101868), POLD4 (ENSG00000175482), POLD3 (ENSG00000077514), POLD1 (ENSG00000062822), POLD2 (ENSG00000106628), POLE (ENSG00000177084), POLA2 (ENSG00000014138), PRIM1 (ENSG00000198... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.701 | Q1 | Is IL5 a druggable gene? | There are currently 2 approved drugs which target IL5, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%IL5 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_5821', 'drugName': 'Reslizumab', 'drugIsApproved': True, 'newLinkedTargets_string': 'IL5 (ENSG00000113525)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_1703', 'drugName': 'Mepolizumab', 'drugIsApproved': True, 'newLinkedTargets_string': 'IL5 (ENSG00000113525)', 'maxClinicalT... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1002 | Q1 | Is NPY4R a druggable gene? | There are currently no approved drugs targeting NPY4R, but there is 1 drug in a clinical trial indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%NPY4R %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_2735', 'drugName': 'Tm30339', 'drugIsApproved': False, 'newLinkedTargets_string': 'NPY4R (ENSG00000204174)', 'maxClinicalTrialPhase': 2}] | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.155 | Q1 | Is CACNA2D4 a druggable gene? | There are currently 9 approved drugs which target CACNA2D4, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%CACNA2D4 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_142', 'drugName': 'Gabapentin', 'drugIsApproved': True, 'newLinkedTargets_string': 'CACNA1H (ENSG00000196557), CACNA2D1 (ENSG00000153956), CACNA1C (ENSG00000151067), CACNA2D3 (ENSG00000157445), CACNA1S (ENSG00000081248), CACNA2D2 (ENSG00000007402), CACNA1D (ENSG00000157388), CACNA1A (ENSG0... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1107 | Q1 | Is POLE2 a druggable gene? | There are currently 5 approved drugs which target POLE2, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%POLE2 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_4', 'drugName': 'Gemcitabine Hydrochloride', 'drugIsApproved': True, 'newLinkedTargets_string': 'POLA1 (ENSG00000101868), POLD4 (ENSG00000175482), POLD3 (ENSG00000077514), POLD1 (ENSG00000062822), POLD2 (ENSG00000106628), POLE (ENSG00000177084), POLA2 (ENSG00000014138), PRIM1 (ENSG00000198... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1332 | Q1 | Is SCN1A a druggable gene? | There are currently 78 approved drugs which target SCN1A, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%SCN1A %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_2256', 'drugName': 'Quinidine Gluconate', 'drugIsApproved': True, 'newLinkedTargets_string': 'SCN1A (ENSG00000144285), SCN5A (ENSG00000183873), SCN4A (ENSG00000007314), SCN7A (ENSG00000136546), SCN2A (ENSG00000136531), SCN9A (ENSG00000169432), SCN3A (ENSG00000153253), SCN11A (ENSG000001683... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1536 | Q1 | Is XPNPEP3 a druggable gene? | There are currently no approved drugs targeting XPNPEP3, but there is 1 drug in a clinical trial indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%XPNPEP3 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_582', 'drugName': 'Tosedostat', 'drugIsApproved': False, 'newLinkedTargets_string': 'ANPEP (ENSG00000166825), NPEPPS (ENSG00000141279), RNPEP (ENSG00000176393), METAP1 (ENSG00000164024), LNPEP (ENSG00000113441), DNPEP (ENSG00000123992), ENPEP (ENSG00000138792), XPNPEP1 (ENSG00000108039), L... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.794 | Q1 | Is KIT a druggable gene? | There are currently 18 approved drugs which target KIT, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%KIT %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_3272', 'drugName': 'Imatinib Mesylate', 'drugIsApproved': True, 'newLinkedTargets_string': 'ABL1 (ENSG00000097007), PDGFRB (ENSG00000113721), KIT (ENSG00000157404), BCR (ENSG00000186716)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_1792', 'drugName': 'Pexidartinib', 'drugIsA... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.584 | Q1 | Is HDAC3 a druggable gene? | There are currently 5 approved drugs which target HDAC3, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%HDAC3 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_2373', 'drugName': 'Vorinostat', 'drugIsApproved': True, 'newLinkedTargets_string': 'HDAC1 (ENSG00000116478), HDAC2 (ENSG00000196591), HDAC3 (ENSG00000171720), HDAC6 (ENSG00000094631)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_2372', 'drugName': 'Vorinostat', 'drugIsApprov... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.708 | Q1 | Is IMPDH1 a druggable gene? | There are currently 6 approved drugs which target IMPDH1, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%IMPDH1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_290', 'drugName': 'Mycophenolate Mofetil', 'drugIsApproved': True, 'newLinkedTargets_string': 'IMPDH1 (ENSG00000106348), IMPDH2 (ENSG00000178035)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_4489', 'drugName': 'Mycophenolate Mofetil Hydrochloride', 'drugIsApproved': True, 'n... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1359 | Q1 | Is SLC10A1 a druggable gene? | There is 1 drug, Bulevirtide, that targets SLC10A1, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%SLC10A1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1428', 'drugName': 'Bulevirtide', 'drugIsApproved': True, 'newLinkedTargets_string': 'SLC10A1 (ENSG00000100652)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_6299', 'drugName': 'Hepalatide', 'drugIsApproved': False, 'newLinkedTargets_string': 'SLC10A1 (ENSG00000100652)', 'max... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.490 | Q1 | Is GAA a druggable gene? | There is 1 drug, Miglitol, that targets GAA, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%GAA %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1114', 'drugName': 'Miglitol', 'drugIsApproved': True, 'newLinkedTargets_string': 'MGAM (ENSG00000257335), GAA (ENSG00000171298)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_1115', 'drugName': 'Miglitol', 'drugIsApproved': True, 'newLinkedTargets_string': 'MGAM (ENSG00000257... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.562 | Q1 | Is GSTP1 a druggable gene? | There are currently no approved drugs targeting GSTP1, but there are 2 drugs in clinical trials indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%GSTP1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_4755', 'drugName': 'Ezatiostat Hydrochloride', 'drugIsApproved': False, 'newLinkedTargets_string': 'GSTP1 (ENSG00000084207)', 'maxClinicalTrialPhase': 2}, {'UUID': 'DrugGeneTargets_v2_3187', 'drugName': 'Ezatiostat', 'drugIsApproved': False, 'newLinkedTargets_string': 'GSTP1 (ENSG000000842... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.806 | Q1 | Is LAMA5 a druggable gene? | There is 1 drug, Ocriplasmin, that targets LAMA5, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%LAMA5 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_5818', 'drugName': 'Ocriplasmin', 'drugIsApproved': True, 'newLinkedTargets_string': 'FN1 (ENSG00000115414), COL1A2 (ENSG00000164692), COL1A1 (ENSG00000108821), COL2A1 (ENSG00000139219), COL3A1 (ENSG00000168542), COL4A1 (ENSG00000187498), COL5A1 (ENSG00000130635), COL6A1 (ENSG00000142156),... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.515 | Q1 | Is GFRA1 a druggable gene? | There are currently no approved drugs targeting GFRA1, but there is 1 drug in a clinical trial indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%GFRA1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_4217', 'drugName': 'Liatermin', 'drugIsApproved': False, 'newLinkedTargets_string': 'GFRA1 (ENSG00000151892)', 'maxClinicalTrialPhase': 1}] | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.637 | Q1 | Is IDH1 a druggable gene? | There is 1 drug, Ivosidenib, that targets IDH1, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%IDH1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1675', 'drugName': 'Ivosidenib', 'drugIsApproved': True, 'newLinkedTargets_string': 'IDH1 (ENSG00000138413)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_1864', 'drugName': 'Vorasidenib', 'drugIsApproved': False, 'newLinkedTargets_string': 'IDH1 (ENSG00000138413), IDH2 (ENSG0... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1262 | Q1 | Is RPL38 a druggable gene? | There is 1 drug, Ataluren, that targets RPL38, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%RPL38 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_3776', 'drugName': 'Ataluren', 'drugIsApproved': True, 'newLinkedTargets_string': 'RPSA (ENSG00000168028), RPS27 (ENSG00000177954), RPS6 (ENSG00000137154), RPS2 (ENSG00000140988), RPS3 (ENSG00000149273), RPS3A (ENSG00000145425), RPS4X (ENSG00000198034), RPS4Y1 (ENSG00000129824), RPS5 (ENSG... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1371 | Q1 | Is SLC44A4 a druggable gene? | There are currently no approved drugs targeting SLC44A4, but there is 1 drug in a clinical trial indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%SLC44A4 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_405', 'drugName': 'Asg-5Me', 'drugIsApproved': False, 'newLinkedTargets_string': 'SLC44A4 (ENSG00000204385), TUBB4B (ENSG00000188229), TUBB1 (ENSG00000101162), TUBA3C (ENSG00000198033), TUBA4A (ENSG00000127824), TUBB3 (ENSG00000258947), TUBA1A (ENSG00000167552), TUBB4A (ENSG00000104833), T... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.795 | Q1 | Is KLB a druggable gene? | There are currently no approved drugs targeting KLB, but there are 3 drugs in clinical trials indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%KLB %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_6330', 'drugName': 'Pegbelfermin', 'drugIsApproved': False, 'newLinkedTargets_string': 'FGF1 (ENSG00000113578), KLB (ENSG00000134962)', 'maxClinicalTrialPhase': 2}, {'UUID': 'DrugGeneTargets_v2_1258', 'drugName': 'Fazpilodemab', 'drugIsApproved': False, 'newLinkedTargets_string': 'FGF1 (EN... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.118 | Q1 | Is BMX a druggable gene? | There are currently no approved drugs targeting BMX, but there is 1 drug in a clinical trial indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%BMX %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_4380', 'drugName': 'Pf-06651600', 'drugIsApproved': False, 'newLinkedTargets_string': 'ITK (ENSG00000113263), BMX (ENSG00000102010), TEC (ENSG00000135605), TXK (ENSG00000074966), BTK (ENSG00000010671), JAK3 (ENSG00000105639)', 'maxClinicalTrialPhase': 3}, {'UUID': 'DrugGeneTargets_v2_4381'... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.745 | Q1 | Is KCNC3 a druggable gene? | There are currently 5 approved drugs which target KCNC3, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%KCNC3 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_5118', 'drugName': 'Guanidine Hydrochloride', 'drugIsApproved': True, 'newLinkedTargets_string': 'KCNQ1 (ENSG00000053918), KCND3 (ENSG00000171385), KCNH2 (ENSG00000055118), KCNA2 (ENSG00000177301), KCNA1 (ENSG00000111262), KCNQ2 (ENSG00000075043), KCNQ3 (ENSG00000184156), KCNA7 (ENSG000001... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1087 | Q1 | Is PKLR a druggable gene? | There are currently 2 approved drugs which target PKLR, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%PKLR %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_2811', 'drugName': 'Mitapivat Sulfate', 'drugIsApproved': True, 'newLinkedTargets_string': 'PKLR (ENSG00000143627)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_4932', 'drugName': 'Mitapivat', 'drugIsApproved': True, 'newLinkedTargets_string': 'PKLR (ENSG00000143627)', 'maxCl... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.835 | Q1 | Is LTBR a druggable gene? | There are currently no approved drugs targeting LTBR, but there is 1 drug in a clinical trial indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%LTBR %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_5148', 'drugName': 'Hcbe-11', 'drugIsApproved': False, 'newLinkedTargets_string': 'LTBR (ENSG00000111321)', 'maxClinicalTrialPhase': 1}] | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.121 | Q1 | Is BRD3 a druggable gene? | There are currently no approved drugs targeting BRD3, but there are 6 drugs in clinical trials indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%BRD3 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_866', 'drugName': 'Pelabresib', 'drugIsApproved': False, 'newLinkedTargets_string': 'BRD2 (ENSG00000204256), BRD4 (ENSG00000141867), BRDT (ENSG00000137948), BRD3 (ENSG00000169925)', 'maxClinicalTrialPhase': 3}, {'UUID': 'DrugGeneTargets_v2_746', 'drugName': 'Apabetalone', 'drugIsApproved':... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.660 | Q1 | Is IGF1 a druggable gene? | There are currently no approved drugs targeting IGF1, but there are 2 drugs in clinical trials indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%IGF1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_4782', 'drugName': 'Dusigitumab', 'drugIsApproved': False, 'newLinkedTargets_string': 'IGF1 (ENSG00000017427), IGF2 (ENSG00000167244)', 'maxClinicalTrialPhase': 2}, {'UUID': 'DrugGeneTargets_v2_4781', 'drugName': 'Dusigitumab', 'drugIsApproved': False, 'newLinkedTargets_string': 'IGF1 (ENS... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1461 | Q1 | Is TNNC1 a druggable gene? | There are currently no approved drugs targeting TNNC1, but there is 1 drug in a clinical trial indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%TNNC1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_2198', 'drugName': 'Levosimendan', 'drugIsApproved': False, 'newLinkedTargets_string': 'PDE3A (ENSG00000172572), PDE3B (ENSG00000152270), TNNC1 (ENSG00000114854), TNNI3 (ENSG00000129991), TNNT2 (ENSG00000118194)', 'maxClinicalTrialPhase': 3}, {'UUID': 'DrugGeneTargets_v2_2199', 'drugName':... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.639 | Q1 | Is IDO1 a druggable gene? | There are currently no approved drugs targeting IDO1, but there are 2 drugs in clinical trials indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%IDO1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_6043', 'drugName': 'Linrodostat', 'drugIsApproved': False, 'newLinkedTargets_string': 'IDO1 (ENSG00000131203)', 'maxClinicalTrialPhase': 3}, {'UUID': 'DrugGeneTargets_v2_856', 'drugName': 'Epacadostat', 'drugIsApproved': False, 'newLinkedTargets_string': 'IDO1 (ENSG00000131203)', 'maxClini... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.371 | Q1 | Is DPP4 a druggable gene? | There are currently 8 approved drugs which target DPP4, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%DPP4 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_4272', 'drugName': 'Vildagliptin', 'drugIsApproved': True, 'newLinkedTargets_string': 'DPP4 (ENSG00000197635)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_6010', 'drugName': 'Saxagliptin', 'drugIsApproved': True, 'newLinkedTargets_string': 'DPP4 (ENSG00000197635)', 'maxClini... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.270 | Q1 | Is CHRNA7 a druggable gene? | There are currently no approved drugs targeting CHRNA7, but there are 17 drugs in clinical trials indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%CHRNA7 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_4787', 'drugName': 'Encenicline', 'drugIsApproved': False, 'newLinkedTargets_string': 'CHRNA7 (ENSG00000175344)', 'maxClinicalTrialPhase': 3}, {'UUID': 'DrugGeneTargets_v2_945', 'drugName': 'Nd0801', 'drugIsApproved': False, 'newLinkedTargets_string': 'CHRNA7 (ENSG00000175344)', 'maxClinic... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.659 | Q1 | Is IFNLR1 a druggable gene? | There are currently no approved drugs targeting IFNLR1, but there is 1 drug in a clinical trial indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%IFNLR1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_6155', 'drugName': 'Peginterferon Lambda-1A', 'drugIsApproved': False, 'newLinkedTargets_string': 'IL10RB (ENSG00000243646), IFNLR1 (ENSG00000185436)', 'maxClinicalTrialPhase': 3}] | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.940 | Q1 | Is NDUFA2 a druggable gene? | There are currently 2 approved drugs which target NDUFA2, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%NDUFA2 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1888', 'drugName': 'Metformin Hydrochloride', 'drugIsApproved': True, 'newLinkedTargets_string': 'GPD2 (ENSG00000115159), MT-ND6 (ENSG00000198695), NDUFA10 (ENSG00000130414), NDUFS8 (ENSG00000110717), MT-ND4L (ENSG00000212907), NDUFA6 (ENSG00000184983), MT-ND1 (ENSG00000198888), NDUFB6 (EN... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.827 | Q1 | Is LPA a druggable gene? | There are currently no approved drugs targeting LPA, but there are 2 drugs in clinical trials indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%LPA %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_5695', 'drugName': 'Pelacarsen', 'drugIsApproved': False, 'newLinkedTargets_string': 'LPA (ENSG00000198670)', 'maxClinicalTrialPhase': 3}, {'UUID': 'DrugGeneTargets_v2_3555', 'drugName': 'Olpasiran', 'drugIsApproved': False, 'newLinkedTargets_string': 'LPA (ENSG00000198670)', 'maxClinicalT... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.871 | Q1 | Is MC2R a druggable gene? | There are currently 4 approved drugs which target MC2R, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%MC2R %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_4137', 'drugName': 'Cosyntropin', 'drugIsApproved': True, 'newLinkedTargets_string': 'MC2R (ENSG00000185231)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_2998', 'drugName': 'Corticotropin', 'drugIsApproved': True, 'newLinkedTargets_string': 'MC2R (ENSG00000185231)', 'maxClin... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.47 | Q1 | Is AHR a druggable gene? | There is 1 drug, Tapinarof, that targets AHR, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%AHR %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_192', 'drugName': 'Tapinarof', 'drugIsApproved': True, 'newLinkedTargets_string': 'AHR (ENSG00000106546)', 'maxClinicalTrialPhase': 4}] | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1323 | Q1 | Is RYR1 a druggable gene? | There are currently 2 approved drugs which target RYR1, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%RYR1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_4505', 'drugName': 'Dantrolene Sodium', 'drugIsApproved': True, 'newLinkedTargets_string': 'RYR3 (ENSG00000198838), RYR1 (ENSG00000196218)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_4504', 'drugName': 'Dantrolene Sodium', 'drugIsApproved': True, 'newLinkedTargets_string': ... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.997 | Q1 | Is NPM1 a druggable gene? | There are currently 2 approved drugs which target NPM1, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%NPM1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_5880', 'drugName': 'Crizotinib', 'drugIsApproved': True, 'newLinkedTargets_string': 'MET (ENSG00000105976), ALK (ENSG00000171094), NPM1 (ENSG00000181163), EML4 (ENSG00000143924)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_5878', 'drugName': 'Crizotinib', 'drugIsApproved': T... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.881 | Q1 | Is METAP1D a druggable gene? | There are currently no approved drugs targeting METAP1D, but there is 1 drug in a clinical trial indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%METAP1D %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_582', 'drugName': 'Tosedostat', 'drugIsApproved': False, 'newLinkedTargets_string': 'ANPEP (ENSG00000166825), NPEPPS (ENSG00000141279), RNPEP (ENSG00000176393), METAP1 (ENSG00000164024), LNPEP (ENSG00000113441), DNPEP (ENSG00000123992), ENPEP (ENSG00000138792), XPNPEP1 (ENSG00000108039), L... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.778 | Q1 | Is KCNQ4 a druggable gene? | There are currently 6 approved drugs which target KCNQ4, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%KCNQ4 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_3665', 'drugName': 'Ezogabine', 'drugIsApproved': True, 'newLinkedTargets_string': 'KCNQ1 (ENSG00000053918), KCNQ2 (ENSG00000075043), KCNQ3 (ENSG00000184156), KCNQ5 (ENSG00000185760), KCNQ4 (ENSG00000117013)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_5420', 'drugName': 'Am... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1538 | Q1 | Is YES1 a druggable gene? | There is 1 drug, Dasatinib, that targets YES1, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%YES1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_4602', 'drugName': 'Dasatinib', 'drugIsApproved': True, 'newLinkedTargets_string': 'PDGFRB (ENSG00000113721), FYN (ENSG00000010810), SRC (ENSG00000197122), LCK (ENSG00000182866), YES1 (ENSG00000176105), BLK (ENSG00000136573), HCK (ENSG00000101336), LYN (ENSG00000254087), FRK (ENSG000001118... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.5 | Q1 | Is ABCC1 a druggable gene? | There are currently no approved drugs targeting ABCC1, but there is 1 drug in a clinical trial indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%ABCC1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_5418', 'drugName': 'Biricodar', 'drugIsApproved': False, 'newLinkedTargets_string': 'ABCC1 (ENSG00000103222), ABCB1 (ENSG00000085563)', 'maxClinicalTrialPhase': 2}, {'UUID': 'DrugGeneTargets_v2_5419', 'drugName': 'Biricodar', 'drugIsApproved': False, 'newLinkedTargets_string': 'ABCC1 (ENSG... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1009 | Q1 | Is NR3C2 a druggable gene? | There are currently 12 approved drugs which target NR3C2, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%NR3C2 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_4514', 'drugName': 'Canrenone', 'drugIsApproved': True, 'newLinkedTargets_string': 'NR3C2 (ENSG00000151623)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_2455', 'drugName': 'Spironolactone', 'drugIsApproved': True, 'newLinkedTargets_string': 'NR3C2 (ENSG00000151623)', 'maxCli... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1334 | Q1 | Is SCN3A a druggable gene? | There are currently 78 approved drugs which target SCN3A, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%SCN3A %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_485', 'drugName': 'Mexiletine', 'drugIsApproved': True, 'newLinkedTargets_string': 'SCN1A (ENSG00000144285), SCN5A (ENSG00000183873), SCN4A (ENSG00000007314), SCN7A (ENSG00000136546), SCN2A (ENSG00000136531), SCN9A (ENSG00000169432), SCN3A (ENSG00000153253), SCN11A (ENSG00000168356), SCN8A... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.265 | Q1 | Is CHRNA10 a druggable gene? | There are currently no approved drugs targeting CHRNA10, but there are 2 drugs in clinical trials indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%CHRNA10 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_3405', 'drugName': 'Neramexane', 'drugIsApproved': False, 'newLinkedTargets_string': 'GRIN1 (ENSG00000176884), GRIN2A (ENSG00000183454), GRIN2B (ENSG00000273079), GRIN2D (ENSG00000105464), GRIN3B (ENSG00000116032), GRIN2C (ENSG00000161509), GRIN3A (ENSG00000198785), CHRNA9 (ENSG00000174343... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1213 | Q1 | Is RARG a druggable gene? | There are currently 8 approved drugs which target RARG, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%RARG %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_701', 'drugName': 'Alitretinoin', 'drugIsApproved': True, 'newLinkedTargets_string': 'RXRB (ENSG00000204231), RARG (ENSG00000172819), RXRG (ENSG00000143171), RARB (ENSG00000077092), RARA (ENSG00000131759), RXRA (ENSG00000186350)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_5... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1403 | Q1 | Is STEAP1 a druggable gene? | There are currently no approved drugs targeting STEAP1, but there is 1 drug in a clinical trial indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%STEAP1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_752', 'drugName': 'Vandortuzumab Vedotin', 'drugIsApproved': False, 'newLinkedTargets_string': 'STEAP1 (ENSG00000164647), TUBB4B (ENSG00000188229), TUBB1 (ENSG00000101162), TUBA3C (ENSG00000198033), TUBA4A (ENSG00000127824), TUBB3 (ENSG00000258947), TUBA1A (ENSG00000167552), TUBB4A (ENSG00... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.445 | Q1 | Is F9 a druggable gene? | There is 1 drug, Emicizumab, that targets F9, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%F9 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1455', 'drugName': 'Emicizumab', 'drugIsApproved': True, 'newLinkedTargets_string': 'F9 (ENSG00000101981), F10 (ENSG00000126218)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_1851', 'drugName': 'Nonacog Beta Pegol', 'drugIsApproved': False, 'newLinkedTargets_string': 'F9 (ENS... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1008 | Q1 | Is NR3C1 a druggable gene? | There are currently 72 approved drugs which target NR3C1, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%NR3C1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_670', 'drugName': 'Methylprednisolone Hemisuccinate', 'drugIsApproved': True, 'newLinkedTargets_string': 'NR3C1 (ENSG00000113580)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_218', 'drugName': 'Triamcinolone Acetonide', 'drugIsApproved': True, 'newLinkedTargets_string': 'NR3... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1083 | Q1 | Is PIKFYVE a druggable gene? | There are currently no approved drugs targeting PIKFYVE, but there are 2 drugs in clinical trials indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%PIKFYVE %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_4483', 'drugName': 'Apilimod', 'drugIsApproved': False, 'newLinkedTargets_string': 'PIKFYVE (ENSG00000115020)', 'maxClinicalTrialPhase': 2}, {'UUID': 'DrugGeneTargets_v2_1384', 'drugName': 'Apilimod Mesylate', 'drugIsApproved': False, 'newLinkedTargets_string': 'PIKFYVE (ENSG00000115020)',... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.842 | Q1 | Is MAG a druggable gene? | There are currently no approved drugs targeting MAG, but there are 2 drugs in clinical trials indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%MAG %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_2468', 'drugName': 'Gsk-249320', 'drugIsApproved': False, 'newLinkedTargets_string': 'MAG (ENSG00000105695)', 'maxClinicalTrialPhase': 2}, {'UUID': 'DrugGeneTargets_v2_2768', 'drugName': 'Refanezumab', 'drugIsApproved': False, 'newLinkedTargets_string': 'MAG (ENSG00000105695)', 'maxClinica... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1373 | Q1 | Is SLC5A2 a druggable gene? | There are currently 6 approved drugs which target SLC5A2, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%SLC5A2 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_4365', 'drugName': 'Sotagliflozin', 'drugIsApproved': True, 'newLinkedTargets_string': 'SLC5A1 (ENSG00000100170), SLC5A2 (ENSG00000140675)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_4559', 'drugName': 'Canagliflozin', 'drugIsApproved': True, 'newLinkedTargets_string': 'SLC... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.306 | Q1 | Is COL6A2 a druggable gene? | There are currently 2 approved drugs which target COL6A2, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%COL6A2 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_5818', 'drugName': 'Ocriplasmin', 'drugIsApproved': True, 'newLinkedTargets_string': 'FN1 (ENSG00000115414), COL1A2 (ENSG00000164692), COL1A1 (ENSG00000108821), COL2A1 (ENSG00000139219), COL3A1 (ENSG00000168542), COL4A1 (ENSG00000187498), COL5A1 (ENSG00000130635), COL6A1 (ENSG00000142156),... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1381 | Q1 | Is SMN1 a druggable gene? | There is 1 drug, Onasemnogene Abeparvovec, that targets SMN1, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%SMN1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_3439', 'drugName': 'Onasemnogene Abeparvovec', 'drugIsApproved': True, 'newLinkedTargets_string': 'SMN1 (ENSG00000172062), SMN2 (ENSG00000205571)', 'maxClinicalTrialPhase': 4}] | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.315 | Q1 | Is CRBN a druggable gene? | There are currently 3 approved drugs which target CRBN, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%CRBN %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_64', 'drugName': 'Thalidomide', 'drugIsApproved': True, 'newLinkedTargets_string': 'CRBN (ENSG00000113851), DDB1 (ENSG00000167986), CUL4A (ENSG00000139842), RBX1 (ENSG00000100387)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_4886', 'drugName': 'Pomalidomide', 'drugIsApproved... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.151 | Q1 | Is CACNA1S a druggable gene? | There are currently 35 approved drugs which target CACNA1S, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%CACNA1S %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_6292', 'drugName': 'Terodiline', 'drugIsApproved': True, 'newLinkedTargets_string': 'CHRM3 (ENSG00000133019), CHRM4 (ENSG00000180720), CHRM1 (ENSG00000168539), CHRM2 (ENSG00000181072), CHRM5 (ENSG00000184984), CACNA1H (ENSG00000196557), CACNA2D1 (ENSG00000153956), CACNA1C (ENSG00000151067)... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1156 | Q1 | Is PSMA6 a druggable gene? | There are currently 4 approved drugs which target PSMA6, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%PSMA6 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_3334', 'drugName': 'Ixazomib', 'drugIsApproved': True, 'newLinkedTargets_string': 'PSMD1 (ENSG00000173692), PSMB2 (ENSG00000126067), PSMB1 (ENSG00000008018), PSMB5 (ENSG00000100804), PSMB8 (ENSG00000204264), PSMB9 (ENSG00000240065), PSMB6 (ENSG00000142507), PSMD14 (ENSG00000115233), PSMA1 ... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.578 | Q1 | Is HCRTR1 a druggable gene? | There are currently 4 approved drugs which target HCRTR1, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%HCRTR1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_5696', 'drugName': 'Daridorexant Hydrochloride', 'drugIsApproved': True, 'newLinkedTargets_string': 'HCRTR2 (ENSG00000137252), HCRTR1 (ENSG00000121764)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_4412', 'drugName': 'Daridorexant', 'drugIsApproved': True, 'newLinkedTargets_s... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.51 | Q1 | Is AKT3 a druggable gene? | There are currently no approved drugs targeting AKT3, but there are 14 drugs in clinical trials indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%AKT3 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_6037', 'drugName': 'Capivasertib', 'drugIsApproved': False, 'newLinkedTargets_string': 'AKT2 (ENSG00000105221), AKT3 (ENSG00000117020), AKT1 (ENSG00000142208)', 'maxClinicalTrialPhase': 3}, {'UUID': 'DrugGeneTargets_v2_2935', 'drugName': 'Ipatasertib', 'drugIsApproved': False, 'newLinkedTa... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1200 | Q1 | Is PTHLH a druggable gene? | There are currently no approved drugs targeting PTHLH, but there is 1 drug in a clinical trial indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%PTHLH %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_442', 'drugName': 'Cal', 'drugIsApproved': False, 'newLinkedTargets_string': 'PTHLH (ENSG00000087494)', 'maxClinicalTrialPhase': 2}] | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.731 | Q1 | Is JAK2 a druggable gene? | There are currently 10 approved drugs which target JAK2, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%JAK2 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_3179', 'drugName': 'Ruxolitinib', 'drugIsApproved': True, 'newLinkedTargets_string': 'JAK1 (ENSG00000162434), JAK2 (ENSG00000096968)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_4275', 'drugName': 'Pacritinib', 'drugIsApproved': True, 'newLinkedTargets_string': 'FLT3 (ENSG00... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.838 | Q1 | Is LY75 a druggable gene? | There are currently no approved drugs targeting LY75, but there is 1 drug in a clinical trial indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%LY75 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_5339', 'drugName': 'Rasdegafusp Alfa', 'drugIsApproved': False, 'newLinkedTargets_string': 'LY75 (ENSG00000054219), CTAG1B (ENSG00000184033), CTAG1A (ENSG00000268651)', 'maxClinicalTrialPhase': 2}, {'UUID': 'DrugGeneTargets_v2_5340', 'drugName': 'Rasdegafusp Alfa', 'drugIsApproved': False,... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1123 | Q1 | Is PRIM2 a druggable gene? | There are currently 5 approved drugs which target PRIM2, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%PRIM2 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_4', 'drugName': 'Gemcitabine Hydrochloride', 'drugIsApproved': True, 'newLinkedTargets_string': 'POLA1 (ENSG00000101868), POLD4 (ENSG00000175482), POLD3 (ENSG00000077514), POLD1 (ENSG00000062822), POLD2 (ENSG00000106628), POLE (ENSG00000177084), POLA2 (ENSG00000014138), PRIM1 (ENSG00000198... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1174 | Q1 | Is PSMC5 a druggable gene? | There are currently 4 approved drugs which target PSMC5, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%PSMC5 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_559', 'drugName': 'Bortezomib', 'drugIsApproved': True, 'newLinkedTargets_string': 'PSMD1 (ENSG00000173692), PSMB2 (ENSG00000126067), PSMB1 (ENSG00000008018), PSMB5 (ENSG00000100804), PSMB8 (ENSG00000204264), PSMB9 (ENSG00000240065), PSMB6 (ENSG00000142507), PSMD14 (ENSG00000115233), PSMA1... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.472 | Q1 | Is FLT1 a druggable gene? | There are currently 15 approved drugs which target FLT1, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%FLT1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_3921', 'drugName': 'Sunitinib Malate', 'drugIsApproved': True, 'newLinkedTargets_string': 'PDGFRB (ENSG00000113721), PDGFRA (ENSG00000134853), RET (ENSG00000165731), FLT1 (ENSG00000102755), FLT4 (ENSG00000037280), KDR (ENSG00000128052), CSF1R (ENSG00000182578), FLT3 (ENSG00000122025), KIT ... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.977 | Q1 | Is NDUFV3 a druggable gene? | There are currently 2 approved drugs which target NDUFV3, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%NDUFV3 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1888', 'drugName': 'Metformin Hydrochloride', 'drugIsApproved': True, 'newLinkedTargets_string': 'GPD2 (ENSG00000115159), MT-ND6 (ENSG00000198695), NDUFA10 (ENSG00000130414), NDUFS8 (ENSG00000110717), MT-ND4L (ENSG00000212907), NDUFA6 (ENSG00000184983), MT-ND1 (ENSG00000198888), NDUFB6 (EN... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.657 | Q1 | Is IFNGR1 a druggable gene? | There is 1 drug, Interferon Gamma-1B, that targets IFNGR1, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%IFNGR1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_3679', 'drugName': 'Interferon Gamma-1B', 'drugIsApproved': True, 'newLinkedTargets_string': 'IFNGR2 (ENSG00000159128), IFNGR1 (ENSG00000027697)', 'maxClinicalTrialPhase': 4}] | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.401 | Q1 | Is ENG a druggable gene? | There are currently no approved drugs targeting ENG, but there is 1 drug in a clinical trial indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%ENG %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_330', 'drugName': 'Carotuximab', 'drugIsApproved': False, 'newLinkedTargets_string': 'ENG (ENSG00000106991)', 'maxClinicalTrialPhase': 3}] | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.514 | Q1 | Is GDF2 a druggable gene? | There are currently no approved drugs targeting GDF2, but there is 1 drug in a clinical trial indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%GDF2 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_887', 'drugName': 'Dalantercept', 'drugIsApproved': False, 'newLinkedTargets_string': 'GDF2 (ENSG00000263761), BMP10 (ENSG00000163217)', 'maxClinicalTrialPhase': 3}, {'UUID': 'DrugGeneTargets_v2_888', 'drugName': 'Dalantercept', 'drugIsApproved': False, 'newLinkedTargets_string': 'GDF2 (EN... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.322 | Q1 | Is CSF2RA a druggable gene? | There is 1 drug, Sargramostim, that targets CSF2RA, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%CSF2RA %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_5636', 'drugName': 'Sargramostim', 'drugIsApproved': True, 'newLinkedTargets_string': 'CSF2RA (ENSG00000198223), CSF2RB (ENSG00000100368)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_4751', 'drugName': 'Mavrilimumab', 'drugIsApproved': False, 'newLinkedTargets_string': 'CSF2... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.20 | Q1 | Is ADH1A a druggable gene? | There are currently 2 approved drugs which target ADH1A, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%ADH1A %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1663', 'drugName': 'Fomepizole', 'drugIsApproved': True, 'newLinkedTargets_string': 'ADH1A (ENSG00000187758), ADH1B (ENSG00000196616), ADH1C (ENSG00000248144)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_6344', 'drugName': 'Nitrefazole', 'drugIsApproved': True, 'newLinkedTar... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.689 | Q1 | Is IL21 a druggable gene? | There are currently no approved drugs targeting IL21, but there is 1 drug in a clinical trial indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%IL21 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_2251', 'drugName': 'Nnc0114-0006', 'drugIsApproved': False, 'newLinkedTargets_string': 'IL21 (ENSG00000138684)', 'maxClinicalTrialPhase': 2}] | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.36 | Q1 | Is ADRA2B a druggable gene? | There are currently 58 approved drugs which target ADRA2B, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%ADRA2B %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_5908', 'drugName': 'Brimonidine', 'drugIsApproved': True, 'newLinkedTargets_string': 'ADRA2A (ENSG00000150594), ADRA2C (ENSG00000184160), ADRA2B (ENSG00000274286)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_4968', 'drugName': 'Mirtazapine', 'drugIsApproved': True, 'newLinke... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.907 | Q1 | Is MSTN a druggable gene? | There are currently no approved drugs targeting MSTN, but there are 7 drugs in clinical trials indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%MSTN %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_5009', 'drugName': 'Apitegromab', 'drugIsApproved': False, 'newLinkedTargets_string': 'MSTN (ENSG00000138379)', 'maxClinicalTrialPhase': 3}, {'UUID': 'DrugGeneTargets_v2_339', 'drugName': 'Trevogrumab', 'drugIsApproved': False, 'newLinkedTargets_string': 'MSTN (ENSG00000138379)', 'maxClini... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.832 | Q1 | Is LTB a druggable gene? | There are currently no approved drugs targeting LTB, but there is 1 drug in a clinical trial indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%LTB %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_5474', 'drugName': 'Baminercept', 'drugIsApproved': False, 'newLinkedTargets_string': 'LTA (ENSG00000226979), LTB (ENSG00000227507), TNFSF14 (ENSG00000125735)', 'maxClinicalTrialPhase': 2}, {'UUID': 'DrugGeneTargets_v2_5475', 'drugName': 'Baminercept', 'drugIsApproved': False, 'newLinkedTa... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1479 | Q1 | Is TRBV7-9 a druggable gene? | There are currently no approved drugs targeting TRBV7-9, but there are 3 drugs in clinical trials indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%TRBV7-9 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1483', 'drugName': 'Medi-500', 'drugIsApproved': False, 'newLinkedTargets_string': 'TRAV29DV5 (ENSG00000211810), TRAC (ENSG00000277734), TRBV7-9 (ENSG00000278030), TRGV3 (ENSG00000211699)', 'maxClinicalTrialPhase': 3}, {'UUID': 'DrugGeneTargets_v2_5971', 'drugName': 'Tol-101', 'drugIsAppro... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.409 | Q1 | Is EPHA2 a druggable gene? | There are currently 3 approved drugs which target EPHA2, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%EPHA2 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_4603', 'drugName': 'Dasatinib', 'drugIsApproved': True, 'newLinkedTargets_string': 'PDGFRB (ENSG00000113721), FYN (ENSG00000010810), SRC (ENSG00000197122), LCK (ENSG00000182866), YES1 (ENSG00000176105), BLK (ENSG00000136573), HCK (ENSG00000101336), LYN (ENSG00000254087), FRK (ENSG000001118... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.925 | Q1 | Is MYL2 a druggable gene? | There is 1 drug, Mavacamten, that targets MYL2, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%MYL2 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1036', 'drugName': 'Mavacamten', 'drugIsApproved': True, 'newLinkedTargets_string': 'MYH7 (ENSG00000092054), MYH6 (ENSG00000197616), MYH7B (ENSG00000078814), MYL3 (ENSG00000160808), MYL2 (ENSG00000111245), MYL7 (ENSG00000106631), MYL4 (ENSG00000198336)', 'maxClinicalTrialPhase': 4}, {'UUID... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.540 | Q1 | Is GRIA2 a druggable gene? | There are currently 2 approved drugs which target GRIA2, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%GRIA2 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1597', 'drugName': 'Topiramate', 'drugIsApproved': True, 'newLinkedTargets_string': 'GRIK1 (ENSG00000171189), GRIK5 (ENSG00000105737), GRIK4 (ENSG00000149403), GRIK2 (ENSG00000164418), GRIK3 (ENSG00000163873), CA4 (ENSG00000167434), SCN1A (ENSG00000144285), SCN5A (ENSG00000183873), SCN4A (... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.763 | Q1 | Is KCNJ11 a druggable gene? | There are currently 14 approved drugs which target KCNJ11, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%KCNJ11 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_2335', 'drugName': 'Tolazamide', 'drugIsApproved': True, 'newLinkedTargets_string': 'KCNJ11 (ENSG00000187486), ABCC8 (ENSG00000006071)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_2541', 'drugName': 'Gliclazide', 'drugIsApproved': True, 'newLinkedTargets_string': 'KCNJ11 (EN... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1068 | Q1 | Is PDK2 a druggable gene? | There is 1 drug, Sodium Dichloroacetate, that targets PDK2, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%PDK2 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_2764', 'drugName': 'Sodium Dichloroacetate', 'drugIsApproved': True, 'newLinkedTargets_string': 'PDK2 (ENSG00000005882), PDK3 (ENSG00000067992), PDK4 (ENSG00000004799), PDK1 (ENSG00000152256)', 'maxClinicalTrialPhase': 4}] | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.247 | Q1 | Is CDK7 a druggable gene? | There are currently no approved drugs targeting CDK7, but there are 9 drugs in clinical trials indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%CDK7 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_5623', 'drugName': 'Alvocidib', 'drugIsApproved': False, 'newLinkedTargets_string': 'CDK1 (ENSG00000170312), CDK7 (ENSG00000134058), CDK9 (ENSG00000136807), CDK6 (ENSG00000105810), CDK2 (ENSG00000123374), CDK4 (ENSG00000135446)', 'maxClinicalTrialPhase': 3}, {'UUID': 'DrugGeneTargets_v2_56... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1135 | Q1 | Is PRKCB a druggable gene? | There is 1 drug, Midostaurin, that targets PRKCB, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%PRKCB %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_5665', 'drugName': 'Midostaurin', 'drugIsApproved': True, 'newLinkedTargets_string': 'KIT (ENSG00000157404), KDR (ENSG00000128052), PDGFRB (ENSG00000113721), PDGFRA (ENSG00000134853), FLT3 (ENSG00000122025), PRKD3 (ENSG00000115825), PRKCI (ENSG00000163558), PRKCA (ENSG00000154229), PRKCG (... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.789 | Q1 | Is KIF5B a druggable gene? | There are currently 2 approved drugs which target KIF5B, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%KIF5B %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_898', 'drugName': 'Selpercatinib', 'drugIsApproved': True, 'newLinkedTargets_string': 'RET (ENSG00000165731), CCDC6 (ENSG00000108091), KIF5B (ENSG00000170759)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_2688', 'drugName': 'Pralsetinib', 'drugIsApproved': True, 'newLinkedTar... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.492 | Q1 | Is GABBR2 a druggable gene? | There are currently 6 approved drugs which target GABBR2, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%GABBR2 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_3627', 'drugName': 'Baclofen', 'drugIsApproved': True, 'newLinkedTargets_string': 'GABBR1 (ENSG00000204681), GABBR2 (ENSG00000136928)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_2016', 'drugName': 'Magnesium Oxybate', 'drugIsApproved': True, 'newLinkedTargets_string': 'GABB... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.156 | Q1 | Is CACNB1 a druggable gene? | There are currently 9 approved drugs which target CACNB1, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%CACNB1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_142', 'drugName': 'Gabapentin', 'drugIsApproved': True, 'newLinkedTargets_string': 'CACNA1H (ENSG00000196557), CACNA2D1 (ENSG00000153956), CACNA1C (ENSG00000151067), CACNA2D3 (ENSG00000157445), CACNA1S (ENSG00000081248), CACNA2D2 (ENSG00000007402), CACNA1D (ENSG00000157388), CACNA1A (ENSG0... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.966 | Q1 | Is NDUFC2 a druggable gene? | There are currently 2 approved drugs which target NDUFC2, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%NDUFC2 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1888', 'drugName': 'Metformin Hydrochloride', 'drugIsApproved': True, 'newLinkedTargets_string': 'GPD2 (ENSG00000115159), MT-ND6 (ENSG00000198695), NDUFA10 (ENSG00000130414), NDUFS8 (ENSG00000110717), MT-ND4L (ENSG00000212907), NDUFA6 (ENSG00000184983), MT-ND1 (ENSG00000198888), NDUFB6 (EN... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.858 | Q1 | Is MAPK10 a druggable gene? | There are currently no approved drugs targeting MAPK10, but there are 5 drugs in clinical trials indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%MAPK10 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_504', 'drugName': 'Brimapitide, C-Terminal Acid', 'drugIsApproved': False, 'newLinkedTargets_string': 'MAPK10 (ENSG00000109339)', 'maxClinicalTrialPhase': 3}, {'UUID': 'DrugGeneTargets_v2_2905', 'drugName': 'Brimapitide', 'drugIsApproved': False, 'newLinkedTargets_string': 'MAPK10 (ENSG000... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.629 | Q1 | Is HTR5A a druggable gene? | There are currently 5 approved drugs which target HTR5A, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%HTR5A %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1378', 'drugName': 'Amisulpride', 'drugIsApproved': True, 'newLinkedTargets_string': 'HTR1F (ENSG00000179097), HTR2B (ENSG00000135914), HTR4 (ENSG00000164270), HTR1B (ENSG00000135312), HTR3A (ENSG00000166736), HTR1A (ENSG00000178394), HTR1D (ENSG00000179546), HTR2A (ENSG00000102468), HTR2C... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.690 | Q1 | Is IL22 a druggable gene? | There are currently no approved drugs targeting IL22, but there is 1 drug in a clinical trial indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%IL22 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_6', 'drugName': 'Fezakinumab', 'drugIsApproved': False, 'newLinkedTargets_string': 'IL22 (ENSG00000127318)', 'maxClinicalTrialPhase': 2}] | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.572 | Q1 | Is HBA2 a druggable gene? | There is 1 drug, Voxelotor, that targets HBA2, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%HBA2 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_2318', 'drugName': 'Voxelotor', 'drugIsApproved': True, 'newLinkedTargets_string': 'HBA1 (ENSG00000206172), HBA2 (ENSG00000188536), HBB (ENSG00000244734)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_5816', 'drugName': 'Efaproxiral', 'drugIsApproved': False, 'newLinkedTargets... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1472 | Q1 | Is TPBG a druggable gene? | There are currently no approved drugs targeting TPBG, but there are 4 drugs in clinical trials indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%TPBG %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1150', 'drugName': 'Anatumomab Mafenatox', 'drugIsApproved': False, 'newLinkedTargets_string': 'TPBG (ENSG00000146242)', 'maxClinicalTrialPhase': 2}, {'UUID': 'DrugGeneTargets_v2_5443', 'drugName': 'Naptumomab Estafenatox', 'drugIsApproved': False, 'newLinkedTargets_string': 'TPBG (ENSG000... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.18 | Q1 | Is ADAM17 a druggable gene? | There are currently no approved drugs targeting ADAM17, but there is 1 drug in a clinical trial indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%ADAM17 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_4215', 'drugName': 'Apratastat', 'drugIsApproved': False, 'newLinkedTargets_string': 'MMP13 (ENSG00000137745), ADAM17 (ENSG00000151694)', 'maxClinicalTrialPhase': 2}, {'UUID': 'DrugGeneTargets_v2_4216', 'drugName': 'Apratastat', 'drugIsApproved': False, 'newLinkedTargets_string': 'MMP13 (E... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.129 | Q1 | Is C5AR1 a druggable gene? | There is 1 drug, Avacopan, that targets C5AR1, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%C5AR1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_5921', 'drugName': 'Avacopan', 'drugIsApproved': True, 'newLinkedTargets_string': 'C5AR1 (ENSG00000197405)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_4794', 'drugName': 'Avdoralimab', 'drugIsApproved': False, 'newLinkedTargets_string': 'C5AR1 (ENSG00000197405)', 'maxClinic... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1512 | Q1 | Is TXNRD1 a druggable gene? | There are currently 2 approved drugs which target TXNRD1, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%TXNRD1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_975', 'drugName': 'Arsenic Trioxide', 'drugIsApproved': True, 'newLinkedTargets_string': 'TXNRD1 (ENSG00000198431)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_5394', 'drugName': 'Aurothioglucose', 'drugIsApproved': True, 'newLinkedTargets_string': 'TXNRD1 (ENSG00000198431)'... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.932 | Q1 | Is NCBP1 a druggable gene? | There are currently no approved drugs targeting NCBP1, but there is 1 drug in a clinical trial indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%NCBP1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_3077', 'drugName': 'Obefazimod', 'drugIsApproved': False, 'newLinkedTargets_string': 'NCBP2 (ENSG00000114503), NCBP1 (ENSG00000136937)', 'maxClinicalTrialPhase': 2}] | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
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