uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
values | bio_category stringclasses 14
values |
|---|---|---|---|---|---|---|---|---|
Q58.305 | Q58 | How many genes does the drug Buprenorphine Hydrochloride target and what are they? | There are 2 gene targets for the drug Buprenorphine Hydrochloride: OPRM1 and OPRK1. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, numberLinkedTargets, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%buprenorphine hydrochloride%" OR LOWER(tradeName... | [{'UUID': 'DrugGeneTargets_v2_2028', 'drugName': 'Buprenorphine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRM1 (ENSG00000112038), OPRK1 (ENSG00000082556)', 'numberLinkedTargets': 2, 'yearOfFirstApproval': 1981, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'Drug... | general | Distinct, Order By, Similarity Search | Genetic Target |
Q58.502 | Q58 | How many genes does the drug Cytarabine target and what are they? | There are 11 gene targets for the drug Cytarabine: POLA1, POLD4, POLD3, POLD1, POLD2, POLE, POLA2, PRIM1, PRIM2, POLE2, and POLE3. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, numberLinkedTargets, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%cytarabine%" OR LOWER(tradeNames_string) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4349', 'drugName': 'Cytarabine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'POLA1 (ENSG00000101868), POLD4 (ENSG00000175482), POLD3 (ENSG00000077514), POLD1 (ENSG00000062822), POLD2 (ENSG00000106628), POLE (ENSG00000177084), POLA2 (ENSG00000014138), PRIM1 (ENSG00000... | general | Distinct, Order By, Similarity Search | Genetic Target |
Q58.1696 | Q58 | How many genes does the drug Butalbital target and what are they? | There are 16 gene targets for the drug Butalbital: GABRA1, GABRB2, GABRG2, GABRB3, GABRA4, GABRG3, GABRQ, GABRA3, GABRP, GABRD, GABRG1, GABRB1, GABRE, GABRA2, GABRA5, and GABRA6. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, numberLinkedTargets, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%butalbital%" OR LOWER(tradeNames_string) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3415', 'drugName': 'Butalbital', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GABRA1 (ENSG00000022355), GABRB2 (ENSG00000145864), GABRG2 (ENSG00000113327), GABRB3 (ENSG00000166206), GABRA4 (ENSG00000109158), GABRG3 (ENSG00000182256), GABRQ (ENSG00000268089), GABRA3 (E... | general | Distinct, Order By, Similarity Search | Genetic Target |
Q58.1721 | Q58 | How many genes does the drug Lazertinib target and what are they? | The drug Lazertinib is not approved by the FDA. However, it is currently undergoing clinical trials and indecated to target the gene EGFR. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, numberLinkedTargets, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%lazertinib%" OR LOWER(tradeNames_string) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4340', 'drugName': 'Lazertinib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'EGFR (ENSG00000146648)', 'numberLinkedTargets': 1, 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Order By, Similarity Search | Genetic Target |
Q58.1662 | Q58 | How many genes does the drug Fluticasone Propionate target and what are they? | NR3C1 is the only gene target of drug Fluticasone Propionate. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, numberLinkedTargets, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%fluticasone propionate%" OR LOWER(tradeNames_str... | [{'UUID': 'DrugGeneTargets_v2_5997', 'drugName': 'Fluticasone Propionate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C1 (ENSG00000113580)', 'numberLinkedTargets': 1, 'yearOfFirstApproval': 1990, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Order By, Similarity Search | Genetic Target |
Q58.1639 | Q58 | How many genes does the drug At-7519 target and what are they? | The drug At-7519 is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target 20 genes: CDK1, CDK4, CDK2, CDK5, CDK6, CDK7, CDK3, CDK16, CDK18, CDK8, CDK17, CDK11B, CDK15, CDK19, CDK14, CDK9, CDK10, CDK13, CDK20, and CDK12. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, numberLinkedTargets, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%at-7519%" OR LOWER(tradeNames_string) LIKE "%at-... | [{'UUID': 'DrugGeneTargets_v2_2272', 'drugName': 'At-7519', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CDK1 (ENSG00000170312), CDK4 (ENSG00000135446), CDK2 (ENSG00000123374), CDK5 (ENSG00000164885), CDK6 (ENSG00000105810), CDK7 (ENSG00000134058), CDK3 (ENSG00000250506), CDK16 (ENSG00000102225), ... | general | Distinct, Order By, Similarity Search | Genetic Target |
Q58.523 | Q58 | How many genes does the drug Rivoceranib target and what are they? | The drug Rivoceranib is not approved by the FDA. However, it is currently undergoing clinical trials and indecated to target the gene KDR. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, numberLinkedTargets, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%rivoceranib%" OR LOWER(tradeNames_string) LIKE "... | [{'UUID': 'DrugGeneTargets_v2_367', 'drugName': 'Rivoceranib Mesylate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'KDR (ENSG00000128052)', 'numberLinkedTargets': 1, 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_3065', 'drugName': 'Ri... | general | Distinct, Order By, Similarity Search | Genetic Target |
Q58.1985 | Q58 | How many genes does the drug Betaine Hydrochloride target and what are they? | There are 2 gene targets for the drug Betaine Hydrochloride: BHMT and BHMT2. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, numberLinkedTargets, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%betaine hydrochloride%" OR LOWER(tradeNames_stri... | [{'UUID': 'DrugGeneTargets_v2_1270', 'drugName': 'Betaine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'BHMT (ENSG00000145692), BHMT2 (ENSG00000132840)', 'numberLinkedTargets': 2, 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Order By, Similarity Search | Genetic Target |
Q58.1078 | Q58 | How many genes does the drug Levosalbutamol target and what are they? | ADRB2 is the only gene target of drug Levosalbutamol. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, numberLinkedTargets, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%levosalbutamol%" OR LOWER(tradeNames_string) LIK... | [{'UUID': 'DrugGeneTargets_v2_3721', 'drugName': 'Levosalbutamol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB2 (ENSG00000169252)', 'numberLinkedTargets': 1, 'yearOfFirstApproval': 1999, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2058', 'drugName': 'Lev... | general | Distinct, Order By, Similarity Search | Genetic Target |
Q58.482 | Q58 | How many genes does the drug Mepazine Acetate target and what are they? | MALT1 is the only gene target of drug Mepazine Acetate. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, numberLinkedTargets, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%mepazine acetate%" OR LOWER(tradeNames_string) L... | [{'UUID': 'DrugGeneTargets_v2_1820', 'drugName': 'Mepazine Acetate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MALT1 (ENSG00000172175)', 'numberLinkedTargets': 1, 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Order By, Similarity Search | Genetic Target |
Q58.160 | Q58 | How many genes does the drug Bms-741672 target and what are they? | The drug Bms-741672 is not approved by the FDA. However, it is currently undergoing clinical trials and indecated to target the gene CCR2. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, numberLinkedTargets, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%bms-741672%" OR LOWER(tradeNames_string) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1495', 'drugName': 'Bms-741672', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CCR2 (ENSG00000121807)', 'numberLinkedTargets': 1, 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Order By, Similarity Search | Genetic Target |
Q58.1253 | Q58 | How many genes does the drug Tetrabenazine target and what are they? | SLC18A2 is the only gene target of drug Tetrabenazine. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, numberLinkedTargets, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tetrabenazine%" OR LOWER(tradeNames_string) LIKE... | [{'UUID': 'DrugGeneTargets_v2_3455', 'drugName': 'Tetrabenazine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC18A2 (ENSG00000165646)', 'numberLinkedTargets': 1, 'yearOfFirstApproval': 2008, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1735', 'drugName': 'Du... | general | Distinct, Order By, Similarity Search | Genetic Target |
Q58.1205 | Q58 | How many genes does the drug Mycophenolic Acid target and what are they? | There are 2 gene targets for the drug Mycophenolic Acid: IMPDH1 and IMPDH2. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, numberLinkedTargets, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%mycophenolic acid%" OR LOWER(tradeNames_string) ... | [{'UUID': 'DrugGeneTargets_v2_290', 'drugName': 'Mycophenolate Mofetil', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'IMPDH1 (ENSG00000106348), IMPDH2 (ENSG00000178035)', 'numberLinkedTargets': 2, 'yearOfFirstApproval': 1995, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneT... | general | Distinct, Order By, Similarity Search | Genetic Target |
Q58.17 | Q58 | How many genes does the drug Naphazoline Hydrochloride target and what are they? | There are 6 gene targets for the drug Naphazoline Hydrochloride: ADRA1A, ADRA2A, ADRA2C, ADRA1D, ADRA1B, and ADRA2B. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, numberLinkedTargets, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%naphazoline hydrochloride%" OR LOWER(tradeNames_... | [{'UUID': 'DrugGeneTargets_v2_327', 'drugName': 'Naphazoline Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA1A (ENSG00000120907), ADRA2A (ENSG00000150594), ADRA2C (ENSG00000184160), ADRA1D (ENSG00000171873), ADRA1B (ENSG00000170214), ADRA2B (ENSG00000274286)', 'numberLinkedTarget... | general | Distinct, Order By, Similarity Search | Genetic Target |
Q58.1550 | Q58 | How many genes does the drug Histrelin Acetate target and what are they? | GNRHR is the only gene target of drug Histrelin Acetate. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, numberLinkedTargets, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%histrelin acetate%" OR LOWER(tradeNames_string) ... | [{'UUID': 'DrugGeneTargets_v2_3420', 'drugName': 'Histrelin Acetate', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'GNRHR (ENSG00000109163)', 'numberLinkedTargets': 1, 'yearOfFirstApproval': 1991, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Order By, Similarity Search | Genetic Target |
Q58.1081 | Q58 | How many genes does the drug Buspirone Hydrochloride target and what are they? | HTR1A is the only gene target of drug Buspirone Hydrochloride. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, numberLinkedTargets, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%buspirone hydrochloride%" OR LOWER(tradeNames_st... | [{'UUID': 'DrugGeneTargets_v2_4302', 'drugName': 'Buspirone Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR1A (ENSG00000178394)', 'numberLinkedTargets': 1, 'yearOfFirstApproval': 1986, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Order By, Similarity Search | Genetic Target |
Q58.1972 | Q58 | How many genes does the drug Vernakalant target and what are they? | There are 6 gene targets for the drug Vernakalant: KCND3, KCNA5, KCNJ3, KCNJ5, KCNH2, and SCN5A. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, numberLinkedTargets, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%vernakalant%" OR LOWER(tradeNames_string) LIKE "... | [{'UUID': 'DrugGeneTargets_v2_716', 'drugName': 'Vernakalant', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'KCND3 (ENSG00000171385), KCNA5 (ENSG00000130037), KCNJ3 (ENSG00000162989), KCNJ5 (ENSG00000120457), KCNH2 (ENSG00000055118), SCN5A (ENSG00000183873)', 'numberLinkedTargets': 6, 'yearOfFirstA... | general | Distinct, Order By, Similarity Search | Genetic Target |
Q58.552 | Q58 | How many genes does the drug Aurothioglucose target and what are they? | TXNRD1 is the only gene target of drug Aurothioglucose. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, numberLinkedTargets, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%aurothioglucose%" OR LOWER(tradeNames_string) LI... | [{'UUID': 'DrugGeneTargets_v2_4389', 'drugName': 'Palonosetron', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR3A (ENSG00000166736)', 'numberLinkedTargets': 1, 'yearOfFirstApproval': 2003, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5394', 'drugName': 'Aurot... | general | Distinct, Order By, Similarity Search | Genetic Target |
Q58.1554 | Q58 | How many genes does the drug Sulpiride target and what are they? | DRD2 is the only gene target of drug Sulpiride. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, numberLinkedTargets, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%sulpiride%" OR LOWER(tradeNames_string) LIKE "%s... | [{'UUID': 'DrugGeneTargets_v2_5185', 'drugName': 'Sulpiride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD2 (ENSG00000149295)', 'numberLinkedTargets': 1, 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1938', 'drugName': 'Levosulpirid... | general | Distinct, Order By, Similarity Search | Genetic Target |
Q58.665 | Q58 | How many genes does the drug Mecamylamine target and what are they? | There are 2 gene targets for the drug Mecamylamine: CHRNB4 and CHRNA3. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, numberLinkedTargets, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%mecamylamine%" OR LOWER(tradeNames_string) LIKE ... | [{'UUID': 'DrugGeneTargets_v2_1272', 'drugName': 'Mecamylamine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRNB4 (ENSG00000117971), CHRNA3 (ENSG00000080644)', 'numberLinkedTargets': 2, 'yearOfFirstApproval': 1956, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'Dru... | general | Distinct, Order By, Similarity Search | Genetic Target |
Q58.1626 | Q58 | How many genes does the drug Pki-179 target and what are they? | The drug Pki-179 is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target 2 genes: MTOR and PIK3CA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, numberLinkedTargets, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pki-179%" OR LOWER(tradeNames_string) LIKE "%pki... | [{'UUID': 'DrugGeneTargets_v2_6375', 'drugName': 'Pki-179', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MTOR (ENSG00000198793), PIK3CA (ENSG00000121879)', 'numberLinkedTargets': 2, 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_6376', ... | general | Distinct, Order By, Similarity Search | Genetic Target |
Q58.1028 | Q58 | How many genes does the drug Carbidopa target and what are they? | DDC is the only gene target of drug Carbidopa. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, numberLinkedTargets, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%carbidopa%" OR LOWER(tradeNames_string) LIKE "%c... | [{'UUID': 'DrugGeneTargets_v2_3213', 'drugName': 'Carbidopa', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DDC (ENSG00000132437)', 'numberLinkedTargets': 1, 'yearOfFirstApproval': 1975, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4465', 'drugName': 'Carbidopa'... | general | Distinct, Order By, Similarity Search | Genetic Target |
Q58.1994 | Q58 | How many genes does the drug Gsk-1521498 target and what are they? | The drug Gsk-1521498 is not approved by the FDA. However, it is currently undergoing clinical trials and indecated to target the gene OPRM1. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, numberLinkedTargets, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%gsk-1521498%" OR LOWER(tradeNames_string) LIKE "... | [{'UUID': 'DrugGeneTargets_v2_536', 'drugName': 'Gsk-1521498', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRM1 (ENSG00000112038)', 'numberLinkedTargets': 1, 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Order By, Similarity Search | Genetic Target |
Q58.1519 | Q58 | How many genes does the drug Intepirdine target and what are they? | The drug Intepirdine is not approved by the FDA. However, it is currently undergoing clinical trials and indecated to target the gene HTR6. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, numberLinkedTargets, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%intepirdine%" OR LOWER(tradeNames_string) LIKE "... | [{'UUID': 'DrugGeneTargets_v2_2778', 'drugName': 'Intepirdine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR6 (ENSG00000158748)', 'numberLinkedTargets': 1, 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Order By, Similarity Search | Genetic Target |
Q58.968 | Q58 | How many genes does the drug Glycopyrronium target and what are they? | There are 2 gene targets for the drug Glycopyrronium: CHRM3 and CHRM1. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, numberLinkedTargets, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%glycopyrronium%" OR LOWER(tradeNames_string) LIK... | [{'UUID': 'DrugGeneTargets_v2_2996', 'drugName': 'Glycopyrronium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM3 (ENSG00000133019), CHRM1 (ENSG00000168539)', 'numberLinkedTargets': 2, 'yearOfFirstApproval': 1961, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v... | general | Distinct, Order By, Similarity Search | Genetic Target |
Q58.1883 | Q58 | How many genes does the drug Doxorubicin target and what are they? | TOP2A is the only gene target of drug Doxorubicin. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, numberLinkedTargets, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%doxorubicin%" OR LOWER(tradeNames_string) LIKE "... | [{'UUID': 'DrugGeneTargets_v2_484', 'drugName': 'Doxorubicin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TOP2A (ENSG00000131747)', 'numberLinkedTargets': 1, 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4222', 'drugName': 'Doxorubici... | general | Distinct, Order By, Similarity Search | Genetic Target |
Q58.287 | Q58 | How many genes does the drug Chlormadinone Acetate target and what are they? | PGR is the only gene target of drug Chlormadinone Acetate. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, numberLinkedTargets, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%chlormadinone acetate%" OR LOWER(tradeNames_stri... | [{'UUID': 'DrugGeneTargets_v2_3940', 'drugName': 'Chlormadinone Acetate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PGR (ENSG00000082175)', 'numberLinkedTargets': 1, 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Order By, Similarity Search | Genetic Target |
Q59.589 | Q59 | What is the genetic target of the antibody drug Loncastuximab Tesirine, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Loncastuximab Tesirine is CD19. Loncastuximab Tesirine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%loncastuximab tesirine%" OR LOWER(tradeNames_string) LIKE "%loncastu... | [{'UUID': 'DrugGeneTargets_v2_595', 'drugName': 'Loncastuximab Tesirine', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'CD19 (ENSG00000177455)', 'yearOfFirstApproval': 2021, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1868 | Q59 | What is the genetic target of the small molecule drug Sildenafil, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Sildenafil is PDE5A. Sildenafil reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%sildenafil%" OR LOWER(tradeNames_string) LIKE "%sildenafil%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_4134', 'drugName': 'Sildenafil Citrate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PDE5A (ENSG00000138735)', 'yearOfFirstApproval': 1998, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5817', 'drugName': 'Sildenafil', 'drugMolecul... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1061 | Q59 | What is the genetic target of the small molecule drug Cfi-400945, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Cfi-400945 is PLK4. Cfi-400945 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%cfi-400945%" OR LOWER(tradeNames_string) LIKE "%cfi-400945%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_648', 'drugName': 'Cfi-400945', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PLK4 (ENSG00000142731)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_5521', 'drugName': 'Cfi-400945', 'drugMolecularType': 'Sm... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1084 | Q59 | What is the genetic target of the small molecule drug Vortioxetine Hydrobromide, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Vortioxetine Hydrobromide: SLC6A4, HTR3A, and HTR1A. Vortioxetine Hydrobromide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%vortioxetine hydrobromide%" OR LOWER(tradeNames_string) LIKE "%vorti... | [{'UUID': 'DrugGeneTargets_v2_776', 'drugName': 'Vortioxetine Hydrobromide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A4 (ENSG00000108576), HTR3A (ENSG00000166736), HTR1A (ENSG00000178394)', 'yearOfFirstApproval': 2013, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGen... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.925 | Q59 | What is the genetic target of the protein drug Leuprolide Acetate, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Leuprolide Acetate is GNRHR. Leuprolide Acetate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%leuprolide acetate%" OR LOWER(tradeNames_string) LIKE "%leuprolide a... | [{'UUID': 'DrugGeneTargets_v2_4802', 'drugName': 'Leuprolide Acetate', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'GNRHR (ENSG00000109163)', 'yearOfFirstApproval': 1985, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.73 | Q59 | What is the genetic target of the small molecule drug Cilastatin Sodium, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Cilastatin Sodium is DPEP1. Cilastatin Sodium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%cilastatin sodium%" OR LOWER(tradeNames_string) LIKE "%cilastatin so... | [{'UUID': 'DrugGeneTargets_v2_185', 'drugName': 'Cilastatin Sodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DPEP1 (ENSG00000015413)', 'yearOfFirstApproval': 1985, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.435 | Q59 | What is the genetic target of the antibody drug Urelumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Urelumab is TNFRSF9. Urelumab reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%urelumab%" OR LOWER(tradeNames_string) LIKE "%urelumab%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_1517', 'drugName': 'Urelumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'TNFRSF9 (ENSG00000049249)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.911 | Q59 | What is the genetic target of the small molecule drug Methylphenidate Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Methylphenidate Hydrochloride: SLC6A3 and SLC6A2. Methylphenidate Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%methylphenidate hydrochloride%" OR LOWER(tradeNames_string) LIKE "%m... | [{'UUID': 'DrugGeneTargets_v2_846', 'drugName': 'Methylphenidate Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A3 (ENSG00000142319), SLC6A2 (ENSG00000103546)', 'yearOfFirstApproval': 1955, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_845', 'd... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.922 | Q59 | What is the genetic target of the small molecule drug Repaglinide, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Repaglinide: KCNJ11 and ABCC8. Repaglinide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%repaglinide%" OR LOWER(tradeNames_string) LIKE "%repaglinide%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_2494', 'drugName': 'Repaglinide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'KCNJ11 (ENSG00000187486), ABCC8 (ENSG00000006071)', 'yearOfFirstApproval': 1997, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1679 | Q59 | What is the genetic target of the small molecule drug Tizanidine Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Tizanidine Hydrochloride: ADRA2A, ADRA2C, and ADRA2B. Tizanidine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tizanidine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%tizani... | [{'UUID': 'DrugGeneTargets_v2_5012', 'drugName': 'Tizanidine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA2A (ENSG00000150594), ADRA2C (ENSG00000184160), ADRA2B (ENSG00000274286)', 'yearOfFirstApproval': 1996, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1272 | Q59 | What is the genetic target of the small molecule drug Pravastatin Sodium, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Pravastatin Sodium is HMGCR. Pravastatin Sodium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pravastatin sodium%" OR LOWER(tradeNames_string) LIKE "%pravastatin ... | [{'UUID': 'DrugGeneTargets_v2_1605', 'drugName': 'Pravastatin Sodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HMGCR (ENSG00000113161)', 'yearOfFirstApproval': 1991, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1094 | Q59 | What is the genetic target of the antibody drug Amg-157, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Amg-157 is TSLP. Amg-157 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%amg-157%" OR LOWER(tradeNames_string) LIKE "%amg-157%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_89', 'drugName': 'Amg-157', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'TSLP (ENSG00000145777)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.389 | Q59 | What is the genetic target of the small molecule drug Phenmetrazine Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Phenmetrazine Hydrochloride: SLC6A3 and SLC6A2. Phenmetrazine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%phenmetrazine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%phe... | [{'UUID': 'DrugGeneTargets_v2_4238', 'drugName': 'Phenmetrazine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A3 (ENSG00000142319), SLC6A2 (ENSG00000103546)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4239', 'd... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.841 | Q59 | What is the genetic target of the antibody drug Tocilizumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Tocilizumab is IL6R. Tocilizumab reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tocilizumab%" OR LOWER(tradeNames_string) LIKE "%tocilizumab%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_2072', 'drugName': 'Tocilizumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'IL6R (ENSG00000160712)', 'yearOfFirstApproval': 2005, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.774 | Q59 | What is the genetic target of the small molecule drug Theophylline Glycinate, and what is its status in clinical trials and FDA approval? | There are 10 genetic targets of the small molecule drug Theophylline Glycinate: ADORA1, ADORA2B, ADORA3, ADORA2A, PDE4A, PDE4D, PDE4B, PDE4C, PDE3A, and PDE3B. Theophylline Glycinate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%theophylline glycinate%" OR LOWER(tradeNames_string) LIKE "%theophyl... | [{'UUID': 'DrugGeneTargets_v2_2662', 'drugName': 'Theophylline Glycinate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADORA1 (ENSG00000163485), ADORA2B (ENSG00000170425), ADORA3 (ENSG00000282608), ADORA2A (ENSG00000128271), PDE4A (ENSG00000065989), PDE4D (ENSG00000113448), PDE4B (ENSG00000184588... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1805 | Q59 | What is the genetic target of the small molecule drug Deflazacort, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Deflazacort is NR3C1. Deflazacort reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%deflazacort%" OR LOWER(tradeNames_string) LIKE "%deflazacort%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_4270', 'drugName': 'Deflazacort', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C1 (ENSG00000113580)', 'yearOfFirstApproval': 2017, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1992 | Q59 | What is the genetic target of the small molecule drug Cinaciguat, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Cinaciguat: GUCY1B1, GUCY1B2, GUCY1A2, and GUCY1A1. Cinaciguat reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%cinaciguat%" OR LOWER(tradeNames_string) LIKE "%cinaciguat%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_6276', 'drugName': 'Cinaciguat', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GUCY1B1 (ENSG00000061918), GUCY1B2 (ENSG00000123201), GUCY1A2 (ENSG00000152402), GUCY1A1 (ENSG00000164116)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1066 | Q59 | What is the genetic target of the small molecule drug Teniposide, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Teniposide: TOP2A and TOP2B. Teniposide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%teniposide%" OR LOWER(tradeNames_string) LIKE "%teniposide%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_2612', 'drugName': 'Teniposide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TOP2A (ENSG00000131747), TOP2B (ENSG00000077097)', 'yearOfFirstApproval': 1992, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.58 | Q59 | What is the genetic target of the oligosaccharide drug Muparfostat, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the oligosaccharide drug Muparfostat: HPSE, FGF1, FGF2, and VEGFA. Muparfostat reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%muparfostat%" OR LOWER(tradeNames_string) LIKE "%muparfostat%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_5103', 'drugName': 'Muparfostat', 'drugMolecularType': 'Oligosaccharide', 'newLinkedTargets_string': 'HPSE (ENSG00000173083), FGF1 (ENSG00000113578), FGF2 (ENSG00000138685), VEGFA (ENSG00000112715)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}, {'UUID': '... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1688 | Q59 | What is the genetic target of the small molecule drug Bisoprolol, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Bisoprolol is ADRB1. Bisoprolol reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%bisoprolol%" OR LOWER(tradeNames_string) LIKE "%bisoprolol%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_5313', 'drugName': 'Bisoprolol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB1 (ENSG00000043591)', 'yearOfFirstApproval': 1992, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5408', 'drugName': 'Bisoprolol Fumarate', 'drugMolecu... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1955 | Q59 | What is the genetic target of the small molecule drug Relugolix, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Relugolix is GNRHR. Relugolix reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%relugolix%" OR LOWER(tradeNames_string) LIKE "%relugolix%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_2141', 'drugName': 'Relugolix', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GNRHR (ENSG00000109163)', 'yearOfFirstApproval': 2020, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1218 | Q59 | What is the genetic target of the small molecule drug Dopamine Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Dopamine Hydrochloride is ADRB1. Dopamine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%dopamine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%dopamine... | [{'UUID': 'DrugGeneTargets_v2_4778', 'drugName': 'Dopamine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB1 (ENSG00000043591)', 'yearOfFirstApproval': 1974, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1680 | Q59 | What is the genetic target of the small molecule drug Fluprednisolone, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Fluprednisolone is NR3C1. Fluprednisolone reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%fluprednisolone%" OR LOWER(tradeNames_string) LIKE "%fluprednisolone... | [{'UUID': 'DrugGeneTargets_v2_1579', 'drugName': 'Fluprednisolone', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C1 (ENSG00000113580)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1975 | Q59 | What is the genetic target of the small molecule drug Daunorubicin Citrate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Daunorubicin Citrate is TOP2A. Daunorubicin Citrate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%daunorubicin citrate%" OR LOWER(tradeNames_string) LIKE "%daunorubic... | [{'UUID': 'DrugGeneTargets_v2_1471', 'drugName': 'Daunorubicin Citrate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TOP2A (ENSG00000131747)', 'yearOfFirstApproval': 1996, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.213 | Q59 | What is the genetic target of the oligonucleotide drug Golodirsen, and what is its status in clinical trials and FDA approval? | The genetic target of the oligonucleotide drug Golodirsen is DMD. Golodirsen reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%golodirsen%" OR LOWER(tradeNames_string) LIKE "%golodirsen%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_4074', 'drugName': 'Golodirsen', 'drugMolecularType': 'Oligonucleotide', 'newLinkedTargets_string': 'DMD (ENSG00000198947)', 'yearOfFirstApproval': 2019, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1534 | Q59 | What is the genetic target of the small molecule drug Encainide Hydrochloride, and what is its status in clinical trials and FDA approval? | There are 10 genetic targets of the small molecule drug Encainide Hydrochloride: SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. Encainide Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%encainide hydrochloride%" OR LOWER(tradeNames_string) LIKE "%encaini... | [{'UUID': 'DrugGeneTargets_v2_6219', 'drugName': 'Encainide Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SCN1A (ENSG00000144285), SCN5A (ENSG00000183873), SCN4A (ENSG00000007314), SCN7A (ENSG00000136546), SCN2A (ENSG00000136531), SCN9A (ENSG00000169432), SCN3A (ENSG00000153253), SC... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1135 | Q59 | What is the genetic target of the small molecule drug Fenoldopam, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Fenoldopam is DRD1. Fenoldopam reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%fenoldopam%" OR LOWER(tradeNames_string) LIKE "%fenoldopam%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_4966', 'drugName': 'Fenoldopam', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD1 (ENSG00000184845)', 'yearOfFirstApproval': 1997, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4006', 'drugName': 'Fenoldopam Mesylate', 'drugMolecul... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.131 | Q59 | What is the genetic target of the small molecule drug Lecozotan Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Lecozotan Hydrochloride is HTR1A. Lecozotan Hydrochloride reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%lecozotan hydrochloride%" OR LOWER(tradeNames_string) LIKE "%lecozot... | [{'UUID': 'DrugGeneTargets_v2_6152', 'drugName': 'Lecozotan Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR1A (ENSG00000178394)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.819 | Q59 | What is the genetic target of the small molecule drug Deucravacitinib, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Deucravacitinib is TYK2. Deucravacitinib reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%deucravacitinib%" OR LOWER(tradeNames_string) LIKE "%deucravacitinib... | [{'UUID': 'DrugGeneTargets_v2_1979', 'drugName': 'Deucravacitinib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TYK2 (ENSG00000105397)', 'yearOfFirstApproval': 2022, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_6268', 'drugName': 'Deucravacitinib', 'drugMolecu... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1282 | Q59 | What is the genetic target of the small molecule drug Salmeterol Xinafoate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Salmeterol Xinafoate is ADRB2. Salmeterol Xinafoate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%salmeterol xinafoate%" OR LOWER(tradeNames_string) LIKE "%salmeterol... | [{'UUID': 'DrugGeneTargets_v2_4540', 'drugName': 'Salmeterol Xinafoate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB2 (ENSG00000169252)', 'yearOfFirstApproval': 1994, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1872 | Q59 | What is the genetic target of the small molecule drug Bisoprolol Fumarate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Bisoprolol Fumarate is ADRB1. Bisoprolol Fumarate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%bisoprolol fumarate%" OR LOWER(tradeNames_string) LIKE "%bisoprolol ... | [{'UUID': 'DrugGeneTargets_v2_5408', 'drugName': 'Bisoprolol Fumarate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB1 (ENSG00000043591)', 'yearOfFirstApproval': 1992, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.438 | Q59 | What is the genetic target of the small molecule drug Pamidronate Disodium, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Pamidronate Disodium is FDPS. Pamidronate Disodium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pamidronate disodium%" OR LOWER(tradeNames_string) LIKE "%pamidronat... | [{'UUID': 'DrugGeneTargets_v2_4184', 'drugName': 'Pamidronate Disodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'FDPS (ENSG00000160752)', 'yearOfFirstApproval': 1991, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.417 | Q59 | What is the genetic target of the small molecule drug Cilostazol, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Cilostazol is PDE3A. Cilostazol reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%cilostazol%" OR LOWER(tradeNames_string) LIKE "%cilostazol%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_3317', 'drugName': 'Cilostazol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PDE3A (ENSG00000172572)', 'yearOfFirstApproval': 1999, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1504 | Q59 | What is the genetic target of the small molecule drug Bisegliptin, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Bisegliptin is DPP4. Bisegliptin reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%bisegliptin%" OR LOWER(tradeNames_string) LIKE "%bisegliptin%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_2250', 'drugName': 'Bisegliptin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DPP4 (ENSG00000197635)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.234 | Q59 | What is the genetic target of the small molecule drug Chlorotrianisene, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Chlorotrianisene is ESR2. Chlorotrianisene reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%chlorotrianisene%" OR LOWER(tradeNames_string) LIKE "%chlorotrianise... | [{'UUID': 'DrugGeneTargets_v2_3631', 'drugName': 'Chlorotrianisene', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ESR2 (ENSG00000140009)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1708 | Q59 | What is the genetic target of the small molecule drug Xl-844, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Xl-844: CHEK2 and CHEK1. Xl-844 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%xl-844%" OR LOWER(tradeNames_string) LIKE "%xl-844%" OR LOWER(drugSy... | [{'UUID': 'DrugGeneTargets_v2_1638', 'drugName': 'Xl-844', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHEK2 (ENSG00000183765), CHEK1 (ENSG00000149554)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_1639', 'drugName': 'Xl-844', 'drug... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.895 | Q59 | What is the genetic target of the protein drug Insulin Zinc Susp Semisynthetic Purified Human, and what is its status in clinical trials and FDA approval? | The genetic target of the protein drug Insulin Zinc Susp Semisynthetic Purified Human is INSR. Insulin Zinc Susp Semisynthetic Purified Human reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%insulin zinc susp semisynthetic purified human%" OR LOWER(tradeNames... | [{'UUID': 'DrugGeneTargets_v2_5848', 'drugName': 'Insulin Zinc Susp Semisynthetic Purified Human', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'INSR (ENSG00000171105)', 'yearOfFirstApproval': 1983, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1625 | Q59 | What is the genetic target of the small molecule drug Filanesib, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Filanesib is KIF11. Filanesib reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%filanesib%" OR LOWER(tradeNames_string) LIKE "%filanesib%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_5918', 'drugName': 'Filanesib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'KIF11 (ENSG00000138160)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.699 | Q59 | What is the genetic target of the small molecule drug Distigmine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Distigmine is ACHE. Distigmine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%distigmine%" OR LOWER(tradeNames_string) LIKE "%distigmine%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_2851', 'drugName': 'Distigmine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ACHE (ENSG00000087085)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1769 | Q59 | What is the genetic target of the small molecule drug Gilteritinib, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Gilteritinib: FLT3 and AXL. Gilteritinib reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%gilteritinib%" OR LOWER(tradeNames_string) LIKE "%gilteritinib%" OR ... | [{'UUID': 'DrugGeneTargets_v2_726', 'drugName': 'Gilteritinib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'FLT3 (ENSG00000122025), AXL (ENSG00000167601)', 'yearOfFirstApproval': 2018, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_725', 'drugName': 'Gilteritini... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.301 | Q59 | What is the genetic target of the small molecule drug Valdecoxib, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Valdecoxib is PTGS2. Valdecoxib reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%valdecoxib%" OR LOWER(tradeNames_string) LIKE "%valdecoxib%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_5955', 'drugName': 'Valdecoxib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756)', 'yearOfFirstApproval': 2001, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1399 | Q59 | What is the genetic target of the small molecule drug Cariprazine, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Cariprazine: DRD2 and DRD3. Cariprazine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%cariprazine%" OR LOWER(tradeNames_string) LIKE "%cariprazine%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_4948', 'drugName': 'Cariprazine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD2 (ENSG00000149295), DRD3 (ENSG00000151577)', 'yearOfFirstApproval': 2015, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4947', 'drugNam... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1987 | Q59 | What is the genetic target of the small molecule drug Oxiglutatione, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Oxiglutatione is GSR. Oxiglutatione reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%oxiglutatione%" OR LOWER(tradeNames_string) LIKE "%oxiglutatione%" O... | [{'UUID': 'DrugGeneTargets_v2_4895', 'drugName': 'Oxiglutatione', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GSR (ENSG00000104687)', 'yearOfFirstApproval': 2008, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.102 | Q59 | What is the genetic target of the small molecule drug Pentazocine, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Pentazocine is SIGMAR1. Pentazocine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%pentazocine%" OR LOWER(tradeNames_string) LIKE "%pentazocine%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_1542', 'drugName': 'Pentazocine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SIGMAR1 (ENSG00000147955)', 'yearOfFirstApproval': 1967, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_652', 'drugName': 'Pentazocine Lactate', 'drugMole... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.831 | Q59 | What is the genetic target of the small molecule drug Tridihexethyl Chloride, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Tridihexethyl Chloride: CHRM1 and CHRM3. Tridihexethyl Chloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tridihexethyl chloride%" OR LOWER(tradeNames_string) LIKE "%tridihex... | [{'UUID': 'DrugGeneTargets_v2_5748', 'drugName': 'Tridihexethyl Chloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM1 (ENSG00000168539), CHRM3 (ENSG00000133019)', 'yearOfFirstApproval': 1954, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5749', 'drugName... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.359 | Q59 | What is the genetic target of the small molecule drug Triparanol, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Triparanol is DHCR24. Triparanol reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%triparanol%" OR LOWER(tradeNames_string) LIKE "%triparanol%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_3812', 'drugName': 'Triparanol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DHCR24 (ENSG00000116133)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.114 | Q59 | What is the genetic target of the small molecule drug Verosudil, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Verosudil: ROCK2 and ROCK1. Verosudil reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%verosudil%" OR LOWER(tradeNames_string) LIKE "%verosudil%" OR LOWER(... | [{'UUID': 'DrugGeneTargets_v2_2417', 'drugName': 'Verosudil', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ROCK2 (ENSG00000134318), ROCK1 (ENSG00000067900)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1440 | Q59 | What is the genetic target of the small molecule drug Mecamylamine, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Mecamylamine: CHRNB4 and CHRNA3. Mecamylamine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%mecamylamine%" OR LOWER(tradeNames_string) LIKE "%mecamylamine%" OR ... | [{'UUID': 'DrugGeneTargets_v2_1272', 'drugName': 'Mecamylamine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRNB4 (ENSG00000117971), CHRNA3 (ENSG00000080644)', 'yearOfFirstApproval': 1956, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_120', 'dru... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1840 | Q59 | What is the genetic target of the small molecule drug Seletracetam, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Seletracetam is SV2A. Seletracetam reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%seletracetam%" OR LOWER(tradeNames_string) LIKE "%seletracetam%" OR ... | [{'UUID': 'DrugGeneTargets_v2_5836', 'drugName': 'Seletracetam', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SV2A (ENSG00000159164)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.952 | Q59 | What is the genetic target of the small molecule drug Oxymorphone, and what is its status in clinical trials and FDA approval? | There are 3 genetic targets of the small molecule drug Oxymorphone: OPRK1, OPRD1, and OPRM1. Oxymorphone reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%oxymorphone%" OR LOWER(tradeNames_string) LIKE "%oxymorphone%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_6046', 'drugName': 'Oxycodone', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRM1 (ENSG00000112038)', 'yearOfFirstApproval': 1950, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4591', 'drugName': 'Oxymorphone Hydrochloride', 'drugM... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1186 | Q59 | What is the genetic target of the antibody drug Cirmtuzumab, and what is its status in clinical trials and FDA approval? | The genetic target of the antibody drug Cirmtuzumab is ROR1. Cirmtuzumab reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%cirmtuzumab%" OR LOWER(tradeNames_string) LIKE "%cirmtuzumab%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_5735', 'drugName': 'Cirmtuzumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'ROR1 (ENSG00000185483)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.456 | Q59 | What is the genetic target of the small molecule drug Safotibant, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Safotibant is BDKRB1. Safotibant reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%safotibant%" OR LOWER(tradeNames_string) LIKE "%safotibant%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_6374', 'drugName': 'Safotibant', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'BDKRB1 (ENSG00000100739)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.876 | Q59 | What is the genetic target of the small molecule drug Chlorpromazine, and what is its status in clinical trials and FDA approval? | There are 4 genetic targets of the small molecule drug Chlorpromazine: DRD2, DRD3, DRD4, and HTR2A. Chlorpromazine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%chlorpromazine%" OR LOWER(tradeNames_string) LIKE "%chlorpromazine%"... | [{'UUID': 'DrugGeneTargets_v2_2783', 'drugName': 'Chlorpromazine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD2 (ENSG00000149295), DRD3 (ENSG00000151577), DRD4 (ENSG00000069696), HTR2A (ENSG00000102468)', 'yearOfFirstApproval': 1957, 'maxClinicalTrialPhase': 4, 'drugIsApproved':... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1545 | Q59 | What is the genetic target of the small molecule drug Remoxipride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Remoxipride is DRD2. Remoxipride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%remoxipride%" OR LOWER(tradeNames_string) LIKE "%remoxipride%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_2415', 'drugName': 'Remoxipride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD2 (ENSG00000149295)', 'yearOfFirstApproval': 1990, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3071', 'drugName': 'Remoxipride Hydrochloride', 'drug... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1701 | Q59 | What is the genetic target of the small molecule drug Warfarin Potassium, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Warfarin Potassium is VKORC1. Warfarin Potassium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%warfarin potassium%" OR LOWER(tradeNames_string) LIKE "%warfarin pot... | [{'UUID': 'DrugGeneTargets_v2_5347', 'drugName': 'Warfarin Potassium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'VKORC1 (ENSG00000167397)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1436 | Q59 | What is the genetic target of the small molecule drug Mobocertinib Succinate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Mobocertinib Succinate is EGFR. Mobocertinib Succinate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%mobocertinib succinate%" OR LOWER(tradeNames_string) LIKE "%mobocert... | [{'UUID': 'DrugGeneTargets_v2_1983', 'drugName': 'Mobocertinib Succinate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'EGFR (ENSG00000146648)', 'yearOfFirstApproval': 2021, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.915 | Q59 | What is the genetic target of the small molecule drug Alendronate Sodium, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Alendronate Sodium is FDPS. Alendronate Sodium reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%alendronate sodium%" OR LOWER(tradeNames_string) LIKE "%alendronate ... | [{'UUID': 'DrugGeneTargets_v2_4741', 'drugName': 'Alendronate Sodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'FDPS (ENSG00000160752)', 'yearOfFirstApproval': 1995, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.310 | Q59 | What is the genetic target of the small molecule drug Raloxifene Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Raloxifene Hydrochloride is ESR2. Raloxifene Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%raloxifene hydrochloride%" OR LOWER(tradeNames_string) LIKE "%raloxi... | [{'UUID': 'DrugGeneTargets_v2_1839', 'drugName': 'Raloxifene Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ESR2 (ENSG00000140009)', 'yearOfFirstApproval': 1997, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1257 | Q59 | What is the genetic target of the small molecule drug Mk-7246, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Mk-7246 is PTGDR2. Mk-7246 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%mk-7246%" OR LOWER(tradeNames_string) LIKE "%mk-7246%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_4936', 'drugName': 'Mk-7246', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGDR2 (ENSG00000183134)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1409 | Q59 | What is the genetic target of the small molecule drug Sb-85635, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Sb-85635 is MAPK14. Sb-85635 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%sb-85635%" OR LOWER(tradeNames_string) LIKE "%sb-85635%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_4855', 'drugName': 'Sb-85635', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MAPK14 (ENSG00000112062)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.618 | Q59 | What is the genetic target of the small molecule drug Linagliptin, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Linagliptin is DPP4. Linagliptin reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%linagliptin%" OR LOWER(tradeNames_string) LIKE "%linagliptin%" OR LO... | [{'UUID': 'DrugGeneTargets_v2_745', 'drugName': 'Linagliptin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DPP4 (ENSG00000197635)', 'yearOfFirstApproval': 2011, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1479 | Q59 | What is the genetic target of the small molecule drug Tolazoline, and what is its status in clinical trials and FDA approval? | There are 8 genetic targets of the small molecule drug Tolazoline: HRH1, HRH2, ADRA1A, ADRA2A, ADRA2C, ADRA1D, ADRA1B, and ADRA2B. Tolazoline reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tolazoline%" OR LOWER(tradeNames_string) LIKE "%tolazoline%" OR LOWE... | [{'UUID': 'DrugGeneTargets_v2_2555', 'drugName': 'Tolazoline Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639), HRH2 (ENSG00000113749), ADRA1A (ENSG00000120907), ADRA2A (ENSG00000150594), ADRA2C (ENSG00000184160), ADRA1D (ENSG00000171873), ADRA1B (ENSG00000170214)... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.250 | Q59 | What is the genetic target of the small molecule drug Flurbiprofen, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Flurbiprofen: PTGS2 and PTGS1. Flurbiprofen reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%flurbiprofen%" OR LOWER(tradeNames_string) LIKE "%flurbiprofen%" OR ... | [{'UUID': 'DrugGeneTargets_v2_2737', 'drugName': 'Flurbiprofen Sodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756), PTGS1 (ENSG00000095303)', 'yearOfFirstApproval': 1986, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5775', 'drugName': ... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.734 | Q59 | What is the genetic target of the small molecule drug Levalbuterol Tartrate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Levalbuterol Tartrate is ADRB2. Levalbuterol Tartrate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%levalbuterol tartrate%" OR LOWER(tradeNames_string) LIKE "%levalbute... | [{'UUID': 'DrugGeneTargets_v2_2058', 'drugName': 'Levalbuterol Tartrate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB2 (ENSG00000169252)', 'yearOfFirstApproval': 2005, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.311 | Q59 | What is the genetic target of the small molecule drug Methapyrilene Fumarate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Methapyrilene Fumarate is HRH1. Methapyrilene Fumarate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%methapyrilene fumarate%" OR LOWER(tradeNames_string) LIKE "%methapyr... | [{'UUID': 'DrugGeneTargets_v2_3194', 'drugName': 'Methapyrilene Fumarate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.236 | Q59 | What is the genetic target of the small molecule drug Tipiracil Hydrochloride, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Tipiracil Hydrochloride is TYMP. Tipiracil Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%tipiracil hydrochloride%" OR LOWER(tradeNames_string) LIKE "%tipirac... | [{'UUID': 'DrugGeneTargets_v2_4740', 'drugName': 'Tipiracil Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TYMP (ENSG00000025708)', 'yearOfFirstApproval': 2015, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.72 | Q59 | What is the genetic target of the small molecule drug Phenoxypropazine, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Phenoxypropazine: MAOA and MAOB. Phenoxypropazine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%phenoxypropazine%" OR LOWER(tradeNames_string) LIKE "%phenoxypropazi... | [{'UUID': 'DrugGeneTargets_v2_4642', 'drugName': 'Phenoxypropazine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MAOA (ENSG00000189221), MAOB (ENSG00000069535)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.896 | Q59 | What is the genetic target of the small molecule drug Fluticasone Propionate, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Fluticasone Propionate is NR3C1. Fluticasone Propionate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%fluticasone propionate%" OR LOWER(tradeNames_string) LIKE "%fluticas... | [{'UUID': 'DrugGeneTargets_v2_5997', 'drugName': 'Fluticasone Propionate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C1 (ENSG00000113580)', 'yearOfFirstApproval': 1990, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1754 | Q59 | What is the genetic target of the small molecule drug Volinanserin, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Volinanserin is HTR2A. Volinanserin reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%volinanserin%" OR LOWER(tradeNames_string) LIKE "%volinanserin%" OR ... | [{'UUID': 'DrugGeneTargets_v2_2333', 'drugName': 'Volinanserin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR2A (ENSG00000102468)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.712 | Q59 | What is the genetic target of the small molecule drug Betaine, and what is its status in clinical trials and FDA approval? | There are 2 genetic targets of the small molecule drug Betaine: BHMT and BHMT2. Betaine reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%betaine%" OR LOWER(tradeNames_string) LIKE "%betaine%" OR LOWER(drug... | [{'UUID': 'DrugGeneTargets_v2_3565', 'drugName': 'Betaine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'BHMT (ENSG00000145692), BHMT2 (ENSG00000132840)', 'yearOfFirstApproval': 1996, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1270', 'drugName': 'Betaine Hydr... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1383 | Q59 | What is the genetic target of the small molecule drug Methantheline Bromide, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Methantheline Bromide is HRH2. Methantheline Bromide reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%methantheline bromide%" OR LOWER(tradeNames_string) LIKE "%methanthe... | [{'UUID': 'DrugGeneTargets_v2_3603', 'drugName': 'Methantheline Bromide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH2 (ENSG00000113749)', 'yearOfFirstApproval': 1951, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.1329 | Q59 | What is the genetic target of the small molecule drug Quinidine Polygalacturonate, and what is its status in clinical trials and FDA approval? | There are 10 genetic targets of the small molecule drug Quinidine Polygalacturonate: SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. Quinidine Polygalacturonate reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%quinidine polygalacturonate%" OR LOWER(tradeNames_string) LIKE "%qui... | [{'UUID': 'DrugGeneTargets_v2_154', 'drugName': 'Quinidine Polygalacturonate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SCN1A (ENSG00000144285), SCN5A (ENSG00000183873), SCN4A (ENSG00000007314), SCN7A (ENSG00000136546), SCN2A (ENSG00000136531), SCN9A (ENSG00000169432), SCN3A (ENSG00000153253),... | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
Q59.624 | Q59 | What is the genetic target of the small molecule drug Ursodiol, and what is its status in clinical trials and FDA approval? | The genetic target of the small molecule drug Ursodiol is NR1H4. Ursodiol reached phase 4 clinical trials meaning it has been approved by the FDA. | SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%ursodiol%" OR LOWER(tradeNames_string) LIKE "%ursodiol%" OR LOWER(dr... | [{'UUID': 'DrugGeneTargets_v2_4210', 'drugName': 'Ursodiol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR1H4 (ENSG00000012504)', 'yearOfFirstApproval': 1987, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}] | general | Distinct, Similarity Search, Order By | Approval Status, Trial Phase, Genetic Target |
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