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Q59.1606
Q59
What is the genetic target of the small molecule drug Org-25935, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Org-25935 is SLC6A9. Org-25935 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%org-25935%" OR LOWER(tradeNames_string) LIKE "%org-25935%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_1257', 'drugName': 'Org-25935', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A9 (ENSG00000196517)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.1743
Q59
What is the genetic target of the small molecule drug Bepotastine Besylate, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Bepotastine Besylate is HRH1. Bepotastine Besylate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%bepotastine besylate%" OR LOWER(tradeNames_string) LIKE "%bepotastin...
[{'UUID': 'DrugGeneTargets_v2_3215', 'drugName': 'Bepotastine Besylate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 2009, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.50
Q59
What is the genetic target of the antibody drug Cabiralizumab, and what is its status in clinical trials and FDA approval?
The genetic target of the antibody drug Cabiralizumab is CSF1R. Cabiralizumab reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%cabiralizumab%" OR LOWER(tradeNames_string) LIKE "%cabiralizumab%" O...
[{'UUID': 'DrugGeneTargets_v2_2114', 'drugName': 'Cabiralizumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'CSF1R (ENSG00000182578)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.1089
Q59
What is the genetic target of the small molecule drug Levosalbutamol, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Levosalbutamol is ADRB2. Levosalbutamol reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%levosalbutamol%" OR LOWER(tradeNames_string) LIKE "%levosalbutamol%"...
[{'UUID': 'DrugGeneTargets_v2_3721', 'drugName': 'Levosalbutamol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB2 (ENSG00000169252)', 'yearOfFirstApproval': 1999, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2058', 'drugName': 'Levalbuterol Tartrate', 'drug...
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Q59.1674
Q59
What is the genetic target of the small molecule drug Thalidomide, and what is its status in clinical trials and FDA approval?
There are 4 genetic targets of the small molecule drug Thalidomide: CRBN, DDB1, CUL4A, and RBX1. Thalidomide reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%thalidomide%" OR LOWER(tradeNames_string) LIKE "%thalidomide%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_64', 'drugName': 'Thalidomide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CRBN (ENSG00000113851), DDB1 (ENSG00000167986), CUL4A (ENSG00000139842), RBX1 (ENSG00000100387)', 'yearOfFirstApproval': 1998, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1697
Q59
What is the genetic target of the small molecule drug Metaraminol Bitartrate, and what is its status in clinical trials and FDA approval?
There are 3 genetic targets of the small molecule drug Metaraminol Bitartrate: ADRA1A, ADRA1D, and ADRA1B. Metaraminol Bitartrate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%metaraminol bitartrate%" OR LOWER(tradeNames_string) LIKE "%metarami...
[{'UUID': 'DrugGeneTargets_v2_1846', 'drugName': 'Metaraminol Bitartrate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA1A (ENSG00000120907), ADRA1D (ENSG00000171873), ADRA1B (ENSG00000170214)', 'yearOfFirstApproval': 1954, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.686
Q59
What is the genetic target of the small molecule drug Sarpogrelate, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Sarpogrelate is HTR2A. Sarpogrelate reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%sarpogrelate%" OR LOWER(tradeNames_string) LIKE "%sarpogrelate%" OR ...
[{'UUID': 'DrugGeneTargets_v2_6172', 'drugName': 'Sarpogrelate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR2A (ENSG00000102468)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}]
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Q59.1485
Q59
What is the genetic target of the small molecule drug Tubocurarine Chloride, and what is its status in clinical trials and FDA approval?
There are 5 genetic targets of the small molecule drug Tubocurarine Chloride: CHRNA1, CHRNG, CHRNB1, CHRND, and CHRNE. Tubocurarine Chloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%tubocurarine chloride%" OR LOWER(tradeNames_string) LIKE "%tubocurar...
[{'UUID': 'DrugGeneTargets_v2_5100', 'drugName': 'Tubocurarine Chloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRNA1 (ENSG00000138435), CHRNG (ENSG00000196811), CHRNB1 (ENSG00000170175), CHRND (ENSG00000135902), CHRNE (ENSG00000108556)', 'yearOfFirstApproval': 1945, 'maxClinicalTrialPhase...
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Q59.1455
Q59
What is the genetic target of the small molecule drug Ipragliflozin L-Proline, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Ipragliflozin L-Proline is SLC5A2. Ipragliflozin L-Proline reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%ipragliflozin l-proline%" OR LOWER(tradeNames_string) LIKE "%ipragli...
[{'UUID': 'DrugGeneTargets_v2_2404', 'drugName': 'Ipragliflozin L-Proline', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC5A2 (ENSG00000140675)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}]
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Q59.1486
Q59
What is the genetic target of the small molecule drug Halcinonide, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Halcinonide is NR3C1. Halcinonide reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%halcinonide%" OR LOWER(tradeNames_string) LIKE "%halcinonide%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_5783', 'drugName': 'Halcinonide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C1 (ENSG00000113580)', 'yearOfFirstApproval': 1974, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1292
Q59
What is the genetic target of the small molecule drug Ipratropium, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Ipratropium is CHRM3. Ipratropium reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%ipratropium%" OR LOWER(tradeNames_string) LIKE "%ipratropium%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_4927', 'drugName': 'Ipratropium Bromide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM3 (ENSG00000133019)', 'yearOfFirstApproval': 1986, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3538', 'drugName': 'Ipratropium', 'drugMolec...
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Q59.1232
Q59
What is the genetic target of the small molecule drug Ulipristal, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Ulipristal is PGR. Ulipristal reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%ulipristal%" OR LOWER(tradeNames_string) LIKE "%ulipristal%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_470', 'drugName': 'Ulipristal', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PGR (ENSG00000082175)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4281', 'drugName': 'Ulipristal Acetate', 'drugMolecularType...
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Q59.525
Q59
What is the genetic target of the small molecule drug Dicumarol, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Dicumarol is VKORC1. Dicumarol reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%dicumarol%" OR LOWER(tradeNames_string) LIKE "%dicumarol%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_1631', 'drugName': 'Dicumarol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'VKORC1 (ENSG00000167397)', 'yearOfFirstApproval': 1944, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1654
Q59
What is the genetic target of the small molecule drug Edotecarin, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Edotecarin is TOP1. Edotecarin reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%edotecarin%" OR LOWER(tradeNames_string) LIKE "%edotecarin%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_1978', 'drugName': 'Edotecarin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TOP1 (ENSG00000198900)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}]
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Q59.908
Q59
What is the genetic target of the small molecule drug Carmustine, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Carmustine is GSR. Carmustine reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%carmustine%" OR LOWER(tradeNames_string) LIKE "%carmustine%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_4261', 'drugName': 'Carmustine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GSR (ENSG00000104687)', 'yearOfFirstApproval': 1977, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1904
Q59
What is the genetic target of the small molecule drug Prednisone, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Prednisone is NR3C1. Prednisone reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%prednisone%" OR LOWER(tradeNames_string) LIKE "%prednisone%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_2255', 'drugName': 'Prednisone', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C1 (ENSG00000113580)', 'yearOfFirstApproval': 1955, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5378', 'drugName': 'Meprednisone', 'drugMolecularType...
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Q59.1242
Q59
What is the genetic target of the small molecule drug Bosutinib, and what is its status in clinical trials and FDA approval?
There are 5 genetic targets of the small molecule drug Bosutinib: ABL1, BCR, HCK, SRC, and LYN. Bosutinib reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%bosutinib%" OR LOWER(tradeNames_string) LIKE "%bosutinib%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_3958', 'drugName': 'Bosutinib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ABL1 (ENSG00000097007), BCR (ENSG00000186716), HCK (ENSG00000101336), SRC (ENSG00000197122), LYN (ENSG00000254087)', 'yearOfFirstApproval': 2010, 'maxClinicalTrialPhase': 4, 'drugIsApproved':...
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Q59.24
Q59
What is the genetic target of the small molecule drug Methimazole, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Methimazole is TPO. Methimazole reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%methimazole%" OR LOWER(tradeNames_string) LIKE "%methimazole%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_3174', 'drugName': 'Methimazole', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TPO (ENSG00000115705)', 'yearOfFirstApproval': 1950, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.779
Q59
What is the genetic target of the small molecule drug Benzydamine, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Benzydamine: PTGS2 and PTGS1. Benzydamine reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%benzydamine%" OR LOWER(tradeNames_string) LIKE "%benzydamine%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_3576', 'drugName': 'Benzydamine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756), PTGS1 (ENSG00000095303)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1474', 'drugName...
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Q59.65
Q59
What is the genetic target of the small molecule drug Minodronic Acid, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Minodronic Acid is FDPS. Minodronic Acid reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%minodronic acid%" OR LOWER(tradeNames_string) LIKE "%minodronic acid...
[{'UUID': 'DrugGeneTargets_v2_2268', 'drugName': 'Minodronic Acid', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'FDPS (ENSG00000160752)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}]
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Q59.1366
Q59
What is the genetic target of the small molecule drug Clobetasol Propionate, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Clobetasol Propionate is NR3C1. Clobetasol Propionate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%clobetasol propionate%" OR LOWER(tradeNames_string) LIKE "%clobetaso...
[{'UUID': 'DrugGeneTargets_v2_5376', 'drugName': 'Clobetasol Propionate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C1 (ENSG00000113580)', 'yearOfFirstApproval': 1985, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.191
Q59
What is the genetic target of the antibody drug Caplacizumab, and what is its status in clinical trials and FDA approval?
The genetic target of the antibody drug Caplacizumab is VWF. Caplacizumab reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%caplacizumab%" OR LOWER(tradeNames_string) LIKE "%caplacizumab%" OR ...
[{'UUID': 'DrugGeneTargets_v2_5507', 'drugName': 'Caplacizumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'VWF (ENSG00000110799)', 'yearOfFirstApproval': 2019, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1630
Q59
What is the genetic target of the antibody drug Yttrium Y 90 Epratuzumab Tetraxetan, and what is its status in clinical trials and FDA approval?
The genetic target of the antibody drug Yttrium Y 90 Epratuzumab Tetraxetan is CD22. Yttrium Y 90 Epratuzumab Tetraxetan reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%yttrium y 90 epratuzumab tetraxetan%" OR LOWER(tradeNames_string) LI...
[{'UUID': 'DrugGeneTargets_v2_1182', 'drugName': 'Yttrium Y 90 Epratuzumab Tetraxetan', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'CD22 (ENSG00000012124)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.1395
Q59
What is the genetic target of the antibody drug Zolimomab Aritox, and what is its status in clinical trials and FDA approval?
The genetic target of the antibody drug Zolimomab Aritox is CD5. Zolimomab Aritox reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%zolimomab aritox%" OR LOWER(tradeNames_string) LIKE "%zolimomab arit...
[{'UUID': 'DrugGeneTargets_v2_4169', 'drugName': 'Zolimomab Aritox', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'CD5 (ENSG00000110448)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.1547
Q59
What is the genetic target of the small molecule drug Indomethacin Sodium, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Indomethacin Sodium: PTGS2 and PTGS1. Indomethacin Sodium reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%indomethacin sodium%" OR LOWER(tradeNames_string) LIKE "%indomethaci...
[{'UUID': 'DrugGeneTargets_v2_4252', 'drugName': 'Indomethacin Sodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756), PTGS1 (ENSG00000095303)', 'yearOfFirstApproval': 1985, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.346
Q59
What is the genetic target of the small molecule drug Ralinepag, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Ralinepag is PTGIR. Ralinepag reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%ralinepag%" OR LOWER(tradeNames_string) LIKE "%ralinepag%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_3547', 'drugName': 'Ralinepag', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGIR (ENSG00000160013)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}]
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Q59.400
Q59
What is the genetic target of the small molecule drug Norepinephrine, and what is its status in clinical trials and FDA approval?
There are 9 genetic targets of the small molecule drug Norepinephrine: ADRA1A, ADRA2A, ADRB1, ADRB2, ADRA2C, ADRA1D, ADRA1B, ADRA2B, and ADRB3. Norepinephrine reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%norepinephrine%" OR LOWER(tradeNames_string) LIKE "%norepinephrine%"...
[{'UUID': 'DrugGeneTargets_v2_1992', 'drugName': 'Norepinephrine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA1A (ENSG00000120907), ADRA2A (ENSG00000150594), ADRB1 (ENSG00000043591), ADRB2 (ENSG00000169252), ADRA2C (ENSG00000184160), ADRA1D (ENSG00000171873), ADRA1B (ENSG00000170214), ADRA2B...
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Q59.1393
Q59
What is the genetic target of the small molecule drug Betamethasone Phosphoric Acid, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Betamethasone Phosphoric Acid is NR3C1. Betamethasone Phosphoric Acid reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%betamethasone phosphoric acid%" OR LOWER(tradeNames_string) LIKE "%b...
[{'UUID': 'DrugGeneTargets_v2_2412', 'drugName': 'Betamethasone Phosphoric Acid', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C1 (ENSG00000113580)', 'yearOfFirstApproval': 1965, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1876
Q59
What is the genetic target of the small molecule drug Estramustine Phosphate, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Estramustine Phosphate is ESR2. Estramustine Phosphate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%estramustine phosphate%" OR LOWER(tradeNames_string) LIKE "%estramus...
[{'UUID': 'DrugGeneTargets_v2_5377', 'drugName': 'Estramustine Phosphate Sodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ESR2 (ENSG00000140009)', 'yearOfFirstApproval': 1981, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5789', 'drugName': 'Estramustine Ph...
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Q59.199
Q59
What is the genetic target of the small molecule drug Nilotinib, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Nilotinib: ABL1 and BCR. Nilotinib reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%nilotinib%" OR LOWER(tradeNames_string) LIKE "%nilotinib%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_6061', 'drugName': 'Nilotinib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ABL1 (ENSG00000097007), BCR (ENSG00000186716)', 'yearOfFirstApproval': 2007, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_6060', 'drugName': 'Nilotinib', ...
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Q59.1173
Q59
What is the genetic target of the small molecule drug Mk-8777, and what is its status in clinical trials and FDA approval?
There are 4 genetic targets of the small molecule drug Mk-8777: GRIA4, GRIA3, GRIA2, and GRIA1. Mk-8777 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%mk-8777%" OR LOWER(tradeNames_string) LIKE "%mk-8777%" OR LOWER(drug...
[{'UUID': 'DrugGeneTargets_v2_5646', 'drugName': 'Mk-8777', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GRIA4 (ENSG00000152578), GRIA3 (ENSG00000125675), GRIA2 (ENSG00000120251), GRIA1 (ENSG00000155511)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.320
Q59
What is the genetic target of the small molecule drug Cep-11981, and what is its status in clinical trials and FDA approval?
There are 4 genetic targets of the small molecule drug Cep-11981: TEK, FLT1, FLT4, and KDR. Cep-11981 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%cep-11981%" OR LOWER(tradeNames_string) LIKE "%cep-11981%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_4988', 'drugName': 'Cep-11981', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TEK (ENSG00000120156), FLT1 (ENSG00000102755), FLT4 (ENSG00000037280), KDR (ENSG00000128052)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}, {'UUID': 'DrugGe...
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Q59.1002
Q59
What is the genetic target of the small molecule drug Bitolterol Mesylate, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Bitolterol Mesylate is ADRB2. Bitolterol Mesylate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%bitolterol mesylate%" OR LOWER(tradeNames_string) LIKE "%bitolterol ...
[{'UUID': 'DrugGeneTargets_v2_3535', 'drugName': 'Bitolterol Mesylate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB2 (ENSG00000169252)', 'yearOfFirstApproval': 1984, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.223
Q59
What is the genetic target of the small molecule drug Methyldopate Hydrochloride, and what is its status in clinical trials and FDA approval?
There are 3 genetic targets of the small molecule drug Methyldopate Hydrochloride: ADRA2A, ADRA2C, and ADRA2B. Methyldopate Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%methyldopate hydrochloride%" OR LOWER(tradeNames_string) LIKE "%meth...
[{'UUID': 'DrugGeneTargets_v2_5960', 'drugName': 'Methyldopate Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA2A (ENSG00000150594), ADRA2C (ENSG00000184160), ADRA2B (ENSG00000274286)', 'yearOfFirstApproval': 1962, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1220
Q59
What is the genetic target of the small molecule drug Ibuprofen Lysine, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Ibuprofen Lysine: PTGS2 and PTGS1. Ibuprofen Lysine reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%ibuprofen lysine%" OR LOWER(tradeNames_string) LIKE "%ibuprofen lysi...
[{'UUID': 'DrugGeneTargets_v2_4050', 'drugName': 'Ibuprofen Lysine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756), PTGS1 (ENSG00000095303)', 'yearOfFirstApproval': 2006, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.103
Q59
What is the genetic target of the small molecule drug Cabergoline, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Cabergoline is DRD2. Cabergoline reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%cabergoline%" OR LOWER(tradeNames_string) LIKE "%cabergoline%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_4668', 'drugName': 'Cabergoline', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD2 (ENSG00000149295)', 'yearOfFirstApproval': 1996, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1655
Q59
What is the genetic target of the small molecule drug Nicotine, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Nicotine: CHRNB2 and CHRNA4. Nicotine reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%nicotine%" OR LOWER(tradeNames_string) LIKE "%nicotine%" OR LOWER(dr...
[{'UUID': 'DrugGeneTargets_v2_5052', 'drugName': 'Nicotine Polacrilex', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRNB2 (ENSG00000160716), CHRNA4 (ENSG00000101204)', 'yearOfFirstApproval': 1984, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_687', 'drugName':...
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Q59.949
Q59
What is the genetic target of the small molecule drug Ambenonium Chloride, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Ambenonium Chloride is ACHE. Ambenonium Chloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%ambenonium chloride%" OR LOWER(tradeNames_string) LIKE "%ambenonium ...
[{'UUID': 'DrugGeneTargets_v2_150', 'drugName': 'Ambenonium Chloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ACHE (ENSG00000087085)', 'yearOfFirstApproval': 1956, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1939
Q59
What is the genetic target of the small molecule drug Nortriptyline Hydrochloride, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Nortriptyline Hydrochloride: SLC6A2 and SLC6A4. Nortriptyline Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%nortriptyline hydrochloride%" OR LOWER(tradeNames_string) LIKE "%nor...
[{'UUID': 'DrugGeneTargets_v2_5991', 'drugName': 'Nortriptyline Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A2 (ENSG00000103546), SLC6A4 (ENSG00000108576)', 'yearOfFirstApproval': 1964, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5992', 'd...
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Q59.1914
Q59
What is the genetic target of the protein drug Fe 202767, and what is its status in clinical trials and FDA approval?
The genetic target of the protein drug Fe 202767 is OXTR. Fe 202767 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%fe 202767%" OR LOWER(tradeNames_string) LIKE "%fe 202767%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_1641', 'drugName': 'Fe 202767', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'OXTR (ENSG00000180914)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.1127
Q59
What is the genetic target of the protein drug Insulin Zinc Susp Extended Recombinant Human, and what is its status in clinical trials and FDA approval?
The genetic target of the protein drug Insulin Zinc Susp Extended Recombinant Human is INSR. Insulin Zinc Susp Extended Recombinant Human reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%insulin zinc susp extended recombinant human%" OR LOWER(tradeNames_s...
[{'UUID': 'DrugGeneTargets_v2_4713', 'drugName': 'Insulin Zinc Susp Extended Recombinant Human', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'INSR (ENSG00000171105)', 'yearOfFirstApproval': 1987, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1052
Q59
What is the genetic target of the small molecule drug Oxymetazoline, and what is its status in clinical trials and FDA approval?
There are 6 genetic targets of the small molecule drug Oxymetazoline: ADRA1A, ADRA2A, ADRA2C, ADRA1D, ADRA1B, and ADRA2B. Oxymetazoline reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%oxymetazoline%" OR LOWER(tradeNames_string) LIKE "%oxymetazoline%" O...
[{'UUID': 'DrugGeneTargets_v2_543', 'drugName': 'Oxymetazoline Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA1A (ENSG00000120907), ADRA2A (ENSG00000150594), ADRA2C (ENSG00000184160), ADRA1D (ENSG00000171873), ADRA1B (ENSG00000170214), ADRA2B (ENSG00000274286)', 'yearOfFirstAppro...
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Q59.1538
Q59
What is the genetic target of the small molecule drug Vorapaxar Sulfate, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Vorapaxar Sulfate is F2R. Vorapaxar Sulfate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%vorapaxar sulfate%" OR LOWER(tradeNames_string) LIKE "%vorapaxar sul...
[{'UUID': 'DrugGeneTargets_v2_713', 'drugName': 'Vorapaxar Sulfate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'F2R (ENSG00000181104)', 'yearOfFirstApproval': 2014, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.356
Q59
What is the genetic target of the small molecule drug Crofelemer, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Crofelemer: CFTR and ANO1. Crofelemer reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%crofelemer%" OR LOWER(tradeNames_string) LIKE "%crofelemer%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_2220', 'drugName': 'Crofelemer', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CFTR (ENSG00000001626), ANO1 (ENSG00000131620)', 'yearOfFirstApproval': 2012, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2221', 'drugName': 'Crofelemer...
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Q59.603
Q59
What is the genetic target of the small molecule drug Salmeterol, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Salmeterol is ADRB2. Salmeterol reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%salmeterol%" OR LOWER(tradeNames_string) LIKE "%salmeterol%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_4540', 'drugName': 'Salmeterol Xinafoate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB2 (ENSG00000169252)', 'yearOfFirstApproval': 1994, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4770', 'drugName': 'Salmeterol', 'drugMolec...
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Q59.1559
Q59
What is the genetic target of the small molecule drug Faxeladol, and what is its status in clinical trials and FDA approval?
There are 3 genetic targets of the small molecule drug Faxeladol: SLC6A4, SLC6A2, and OPRM1. Faxeladol reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%faxeladol%" OR LOWER(tradeNames_string) LIKE "%faxeladol%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_523', 'drugName': 'Faxeladol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A4 (ENSG00000108576), SLC6A2 (ENSG00000103546), OPRM1 (ENSG00000112038)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_524',...
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Q59.1350
Q59
What is the genetic target of the small molecule drug Mephentermine Sulfate, and what is its status in clinical trials and FDA approval?
There are 9 genetic targets of the small molecule drug Mephentermine Sulfate: ADRA1A, ADRA2A, ADRB1, ADRB2, ADRA2C, ADRA1D, ADRA1B, ADRA2B, and ADRB3. Mephentermine Sulfate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%mephentermine sulfate%" OR LOWER(tradeNames_string) LIKE "%mephenter...
[{'UUID': 'DrugGeneTargets_v2_4285', 'drugName': 'Mephentermine Sulfate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA1A (ENSG00000120907), ADRA2A (ENSG00000150594), ADRB1 (ENSG00000043591), ADRB2 (ENSG00000169252), ADRA2C (ENSG00000184160), ADRA1D (ENSG00000171873), ADRA1B (ENSG00000170214),...
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Q59.1359
Q59
What is the genetic target of the small molecule drug Chlorpromazine Hydrochloride, and what is its status in clinical trials and FDA approval?
There are 4 genetic targets of the small molecule drug Chlorpromazine Hydrochloride: DRD2, DRD3, DRD4, and HTR2A. Chlorpromazine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%chlorpromazine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%ch...
[{'UUID': 'DrugGeneTargets_v2_2783', 'drugName': 'Chlorpromazine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD2 (ENSG00000149295), DRD3 (ENSG00000151577), DRD4 (ENSG00000069696), HTR2A (ENSG00000102468)', 'yearOfFirstApproval': 1957, 'maxClinicalTrialPhase': 4, 'drugIsApproved':...
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Q59.947
Q59
What is the genetic target of the small molecule drug Cp-866087, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Cp-866087 is OPRM1. Cp-866087 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%cp-866087%" OR LOWER(tradeNames_string) LIKE "%cp-866087%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_3407', 'drugName': 'Cp-866087', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRM1 (ENSG00000112038)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.348
Q59
What is the genetic target of the antibody drug Icm3, and what is its status in clinical trials and FDA approval?
The genetic target of the antibody drug Icm3 is ICAM3. Icm3 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%icm3%" OR LOWER(tradeNames_string) LIKE "%icm3%" OR LOWER(drugSynony...
[{'UUID': 'DrugGeneTargets_v2_1930', 'drugName': 'Icm3', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'ICAM3 (ENSG00000076662)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.606
Q59
What is the genetic target of the small molecule drug Alseroxylon, and what is its status in clinical trials and FDA approval?
There are 6 genetic targets of the small molecule drug Alseroxylon: ADRA1A, ADRA2A, ADRA2C, ADRA1D, ADRA1B, and ADRA2B. Alseroxylon reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%alseroxylon%" OR LOWER(tradeNames_string) LIKE "%alseroxylon%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_4856', 'drugName': 'Rauwolfia Serpentina', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA1A (ENSG00000120907), ADRA2A (ENSG00000150594), ADRA2C (ENSG00000184160), ADRA1D (ENSG00000171873), ADRA1B (ENSG00000170214), ADRA2B (ENSG00000274286)', 'yearOfFirstApproval': ...
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Q59.719
Q59
What is the genetic target of the small molecule drug Benazepril, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Benazepril is ACE. Benazepril reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%benazepril%" OR LOWER(tradeNames_string) LIKE "%benazepril%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_5353', 'drugName': 'Benazepril Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ACE (ENSG00000159640)', 'yearOfFirstApproval': 1991, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5259', 'drugName': 'Benazepril', 'drugMol...
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Q59.118
Q59
What is the genetic target of the small molecule drug Alfentanil, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Alfentanil is OPRM1. Alfentanil reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%alfentanil%" OR LOWER(tradeNames_string) LIKE "%alfentanil%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_793', 'drugName': 'Alfentanil Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRM1 (ENSG00000112038)', 'yearOfFirstApproval': 1986, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2019', 'drugName': 'Alfentanil', 'drugMo...
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Q59.617
Q59
What is the genetic target of the small molecule drug Carboprost, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Carboprost is PTGFR. Carboprost reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%carboprost%" OR LOWER(tradeNames_string) LIKE "%carboprost%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_2928', 'drugName': 'Carboprost Tromethamine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGFR (ENSG00000122420)', 'yearOfFirstApproval': 1979, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5593', 'drugName': 'Carboprost', 'drugMo...
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Q59.1013
Q59
What is the genetic target of the small molecule drug Clidinium, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Clidinium: CHRM3 and CHRM1. Clidinium reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%clidinium%" OR LOWER(tradeNames_string) LIKE "%clidinium%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_73', 'drugName': 'Clidinium Bromide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM3 (ENSG00000133019), CHRM1 (ENSG00000168539)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4584', 'drugName': 'Cli...
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Q59.1265
Q59
What is the genetic target of the small molecule drug Tabimorelin, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Tabimorelin: GHSR and CYP3A4. Tabimorelin reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%tabimorelin%" OR LOWER(tradeNames_string) LIKE "%tabimorelin%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_5300', 'drugName': 'Tabimorelin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GHSR (ENSG00000121853), CYP3A4 (ENSG00000160868)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_5301', 'drugName': 'Tabimorel...
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Q59.1489
Q59
What is the genetic target of the small molecule drug Diethylpropion Hydrochloride, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Diethylpropion Hydrochloride: SLC6A2 and SLC6A3. Diethylpropion Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%diethylpropion hydrochloride%" OR LOWER(tradeNames_string) LIKE "%di...
[{'UUID': 'DrugGeneTargets_v2_2343', 'drugName': 'Diethylpropion Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A2 (ENSG00000103546), SLC6A3 (ENSG00000142319)', 'yearOfFirstApproval': 1959, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2344', '...
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Q59.489
Q59
What is the genetic target of the small molecule drug Cyclopentolate, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Cyclopentolate is CHRM3. Cyclopentolate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%cyclopentolate%" OR LOWER(tradeNames_string) LIKE "%cyclopentolate%"...
[{'UUID': 'DrugGeneTargets_v2_5172', 'drugName': 'Cyclopentolate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM3 (ENSG00000133019)', 'yearOfFirstApproval': 1974, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_6338', 'drugName': 'Cyclopentolate Hydrochloride'...
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Q59.1711
Q59
What is the genetic target of the small molecule drug Tripelennamine Hydrochloride, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Tripelennamine Hydrochloride is HRH1. Tripelennamine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%tripelennamine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%tr...
[{'UUID': 'DrugGeneTargets_v2_5081', 'drugName': 'Tripelennamine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 1948, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.787
Q59
What is the genetic target of the small molecule drug Timolol Maleate, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Timolol Maleate: ADRB2 and ADRB1. Timolol Maleate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%timolol maleate%" OR LOWER(tradeNames_string) LIKE "%timolol maleate...
[{'UUID': 'DrugGeneTargets_v2_760', 'drugName': 'Timolol Maleate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB2 (ENSG00000169252), ADRB1 (ENSG00000043591)', 'yearOfFirstApproval': 1978, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_761', 'drugName': 'Timol...
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Q59.881
Q59
What is the genetic target of the antibody drug Medi-500, and what is its status in clinical trials and FDA approval?
There are 4 genetic targets of the antibody drug Medi-500: TRAV29DV5, TRAC, TRBV7-9, and TRGV3. Medi-500 reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%medi-500%" OR LOWER(tradeNames_string) LIKE "%medi-500%" OR LOWER(dr...
[{'UUID': 'DrugGeneTargets_v2_1483', 'drugName': 'Medi-500', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'TRAV29DV5 (ENSG00000211810), TRAC (ENSG00000277734), TRBV7-9 (ENSG00000278030), TRGV3 (ENSG00000211699)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}]
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Q59.1555
Q59
What is the genetic target of the protein drug Lanreotide, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the protein drug Lanreotide: SSTR5 and SSTR2. Lanreotide reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%lanreotide%" OR LOWER(tradeNames_string) LIKE "%lanreotide%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_2627', 'drugName': 'Lanreotide Acetate', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'SSTR5 (ENSG00000162009), SSTR2 (ENSG00000180616)', 'yearOfFirstApproval': 2007, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2626', 'drugName': 'Lanreot...
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Q59.567
Q59
What is the genetic target of the small molecule drug Tas-115, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Tas-115: MET and KDR. Tas-115 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%tas-115%" OR LOWER(tradeNames_string) LIKE "%tas-115%" OR LOWER(drug...
[{'UUID': 'DrugGeneTargets_v2_532', 'drugName': 'Tas-115', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MET (ENSG00000105976), KDR (ENSG00000128052)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_533', 'drugName': 'Tas-115', 'drugMole...
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Q59.254
Q59
What is the genetic target of the small molecule drug Loratadine, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Loratadine is HRH1. Loratadine reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%loratadine%" OR LOWER(tradeNames_string) LIKE "%loratadine%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_1956', 'drugName': 'Loratadine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 1993, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3239', 'drugName': 'Desloratadine', 'drugMolecularType...
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Q59.242
Q59
What is the genetic target of the small molecule drug Av-101, and what is its status in clinical trials and FDA approval?
There are 7 genetic targets of the small molecule drug Av-101: GRIN1, GRIN2A, GRIN2B, GRIN2D, GRIN3B, GRIN2C, and GRIN3A. Av-101 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%av-101%" OR LOWER(tradeNames_string) LIKE "%av-101%" OR LOWER(drugSy...
[{'UUID': 'DrugGeneTargets_v2_4732', 'drugName': 'Av-101', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GRIN1 (ENSG00000176884), GRIN2A (ENSG00000183454), GRIN2B (ENSG00000273079), GRIN2D (ENSG00000105464), GRIN3B (ENSG00000116032), GRIN2C (ENSG00000161509), GRIN3A (ENSG00000198785)', 'yearOfFirst...
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Q59.176
Q59
What is the genetic target of the protein drug Glucagon, and what is its status in clinical trials and FDA approval?
The genetic target of the protein drug Glucagon is GCGR. Glucagon reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%glucagon%" OR LOWER(tradeNames_string) LIKE "%glucagon%" OR LOWER(dr...
[{'UUID': 'DrugGeneTargets_v2_1857', 'drugName': 'Glucagon', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'GCGR (ENSG00000215644)', 'yearOfFirstApproval': 1998, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4736', 'drugName': 'Dasiglucagon Hydrochloride', 'drugMolecular...
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Q59.824
Q59
What is the genetic target of the small molecule drug Methysergide Maleate, and what is its status in clinical trials and FDA approval?
There are 3 genetic targets of the small molecule drug Methysergide Maleate: HTR2C, HTR2B, and HTR1A. Methysergide Maleate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%methysergide maleate%" OR LOWER(tradeNames_string) LIKE "%methysergi...
[{'UUID': 'DrugGeneTargets_v2_2806', 'drugName': 'Methysergide Maleate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR2C (ENSG00000147246), HTR2B (ENSG00000135914), HTR1A (ENSG00000178394)', 'yearOfFirstApproval': 1962, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTarg...
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Q59.983
Q59
What is the genetic target of the small molecule drug Xanomeline, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Xanomeline: CHRM1 and CHRM4. Xanomeline reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%xanomeline%" OR LOWER(tradeNames_string) LIKE "%xanomeline%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_3335', 'drugName': 'Xanomeline', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM1 (ENSG00000168539), CHRM4 (ENSG00000180720)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_3336', 'drugName': 'Xanomeline...
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Q59.1476
Q59
What is the genetic target of the small molecule drug Anastrozole, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Anastrozole is CYP19A1. Anastrozole reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%anastrozole%" OR LOWER(tradeNames_string) LIKE "%anastrozole%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_3640', 'drugName': 'Anastrozole', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CYP19A1 (ENSG00000137869)', 'yearOfFirstApproval': 1995, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1262
Q59
What is the genetic target of the small molecule drug Ivosidenib, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Ivosidenib is IDH1. Ivosidenib reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%ivosidenib%" OR LOWER(tradeNames_string) LIKE "%ivosidenib%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_1675', 'drugName': 'Ivosidenib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'IDH1 (ENSG00000138413)', 'yearOfFirstApproval': 2018, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1280
Q59
What is the genetic target of the small molecule drug Ripasudil Hydrochloride Dihydrate, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Ripasudil Hydrochloride Dihydrate: ROCK2 and ROCK1. Ripasudil Hydrochloride Dihydrate reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%ripasudil hydrochloride dihydrate%" OR LOWER(tradeNames_string) LIKE...
[{'UUID': 'DrugGeneTargets_v2_3111', 'drugName': 'Ripasudil Hydrochloride Dihydrate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ROCK2 (ENSG00000134318), ROCK1 (ENSG00000067900)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.751
Q59
What is the genetic target of the small molecule drug Flavoxate Hydrochloride, and what is its status in clinical trials and FDA approval?
There are 8 genetic targets of the small molecule drug Flavoxate Hydrochloride: PDE8B, PDE8A, PDE7A, PDE7B, PDE4A, PDE4D, PDE4B, and PDE4C. Flavoxate Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%flavoxate hydrochloride%" OR LOWER(tradeNames_string) LIKE "%flavoxa...
[{'UUID': 'DrugGeneTargets_v2_1987', 'drugName': 'Flavoxate Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PDE8B (ENSG00000113231), PDE8A (ENSG00000073417), PDE7A (ENSG00000205268), PDE7B (ENSG00000171408), PDE4A (ENSG00000065989), PDE4D (ENSG00000113448), PDE4B (ENSG00000184588), PD...
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Q59.561
Q59
What is the genetic target of the small molecule drug Adenosine, and what is its status in clinical trials and FDA approval?
There are 4 genetic targets of the small molecule drug Adenosine: ADORA1, ADORA2B, ADORA3, and ADORA2A. Adenosine reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%adenosine%" OR LOWER(tradeNames_string) LIKE "%adenosine%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_1105', 'drugName': 'Adenosine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADORA1 (ENSG00000163485), ADORA2B (ENSG00000170425), ADORA3 (ENSG00000282608), ADORA2A (ENSG00000128271)', 'yearOfFirstApproval': 1989, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.81
Q59
What is the genetic target of the small molecule drug Azelastine Hydrochloride, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Azelastine Hydrochloride is HRH1. Azelastine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%azelastine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%azelas...
[{'UUID': 'DrugGeneTargets_v2_3567', 'drugName': 'Azelastine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 1996, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1042
Q59
What is the genetic target of the small molecule drug Chlorothiazide Sodium, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Chlorothiazide Sodium is SLC12A3. Chlorothiazide Sodium reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%chlorothiazide sodium%" OR LOWER(tradeNames_string) LIKE "%chlorothi...
[{'UUID': 'DrugGeneTargets_v2_5405', 'drugName': 'Chlorothiazide Sodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC12A3 (ENSG00000070915)', 'yearOfFirstApproval': 1958, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1314
Q59
What is the genetic target of the protein drug Cosyntropin, and what is its status in clinical trials and FDA approval?
The genetic target of the protein drug Cosyntropin is MC2R. Cosyntropin reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%cosyntropin%" OR LOWER(tradeNames_string) LIKE "%cosyntropin%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_4137', 'drugName': 'Cosyntropin', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'MC2R (ENSG00000185231)', 'yearOfFirstApproval': 1970, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.33
Q59
What is the genetic target of the small molecule drug Quinapril Hydrochloride, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Quinapril Hydrochloride is ACE. Quinapril Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%quinapril hydrochloride%" OR LOWER(tradeNames_string) LIKE "%quinapr...
[{'UUID': 'DrugGeneTargets_v2_1269', 'drugName': 'Quinapril Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ACE (ENSG00000159640)', 'yearOfFirstApproval': 1991, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1739
Q59
What is the genetic target of the small molecule drug Dovitinib, and what is its status in clinical trials and FDA approval?
There are 8 genetic targets of the small molecule drug Dovitinib: PDGFRB, PDGFRA, KIT, FLT3, FGFR3, FLT1, FLT4, and KDR. Dovitinib reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%dovitinib%" OR LOWER(tradeNames_string) LIKE "%dovitinib%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_5744', 'drugName': 'Dovitinib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PDGFRB (ENSG00000113721), PDGFRA (ENSG00000134853), KIT (ENSG00000157404), FLT3 (ENSG00000122025), FGFR3 (ENSG00000068078), FLT1 (ENSG00000102755), FLT4 (ENSG00000037280), KDR (ENSG0000012805...
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Q59.358
Q59
What is the genetic target of the small molecule drug Gw-406381, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Gw-406381 is PTGS2. Gw-406381 reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%gw-406381%" OR LOWER(tradeNames_string) LIKE "%gw-406381%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_3746', 'drugName': 'Gw-406381', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}]
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Q59.1077
Q59
What is the genetic target of the small molecule drug Benzhydrocodone, and what is its status in clinical trials and FDA approval?
There are 3 genetic targets of the small molecule drug Benzhydrocodone: OPRK1, OPRD1, and OPRM1. Benzhydrocodone reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%benzhydrocodone%" OR LOWER(tradeNames_string) LIKE "%benzhydrocodone...
[{'UUID': 'DrugGeneTargets_v2_529', 'drugName': 'Benzhydrocodone', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRK1 (ENSG00000082556), OPRD1 (ENSG00000116329), OPRM1 (ENSG00000112038)', 'yearOfFirstApproval': 2018, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2...
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Q59.1692
Q59
What is the genetic target of the small molecule drug Vonoprazan, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Vonoprazan: ATP4A and ATP4B. Vonoprazan reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%vonoprazan%" OR LOWER(tradeNames_string) LIKE "%vonoprazan%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_5640', 'drugName': 'Vonoprazan Fumarate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ATP4A (ENSG00000105675), ATP4B (ENSG00000186009)', 'yearOfFirstApproval': 2022, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5499', 'drugName': ...
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Q59.127
Q59
What is the genetic target of the small molecule drug Hydrocodone, and what is its status in clinical trials and FDA approval?
There are 3 genetic targets of the small molecule drug Hydrocodone: OPRK1, OPRD1, and OPRM1. Hydrocodone reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%hydrocodone%" OR LOWER(tradeNames_string) LIKE "%hydrocodone%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_3008', 'drugName': 'Benzhydrocodone Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRK1 (ENSG00000082556), OPRD1 (ENSG00000116329), OPRM1 (ENSG00000112038)', 'yearOfFirstApproval': 2018, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'Dru...
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Q59.1031
Q59
What is the genetic target of the antibody drug Amg-729, and what is its status in clinical trials and FDA approval?
The genetic target of the antibody drug Amg-729 is CD19. Amg-729 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%amg-729%" OR LOWER(tradeNames_string) LIKE "%amg-729%" OR LOWER(drug...
[{'UUID': 'DrugGeneTargets_v2_1055', 'drugName': 'Amg-729', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'CD19 (ENSG00000177455)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}]
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Q59.399
Q59
What is the genetic target of the small molecule drug Levothyroxine Sodium, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Levothyroxine Sodium: THRA and THRB. Levothyroxine Sodium reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%levothyroxine sodium%" OR LOWER(tradeNames_string) LIKE "%levothyrox...
[{'UUID': 'DrugGeneTargets_v2_83', 'drugName': 'Liothyronine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'THRA (ENSG00000126351), THRB (ENSG00000151090)', 'yearOfFirstApproval': 1956, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5964', 'drugName': 'Levothyrox...
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Q59.444
Q59
What is the genetic target of the small molecule drug Valproic Acid, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Valproic Acid is ALDH5A1. Valproic Acid reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%valproic acid%" OR LOWER(tradeNames_string) LIKE "%valproic acid%" O...
[{'UUID': 'DrugGeneTargets_v2_6237', 'drugName': 'Valproic Acid', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ALDH5A1 (ENSG00000112294)', 'yearOfFirstApproval': 1978, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5683', 'drugName': 'Divalproex Sodium', 'drugMol...
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Q59.166
Q59
What is the genetic target of the small molecule drug Trazodone Hydrochloride, and what is its status in clinical trials and FDA approval?
There are 3 genetic targets of the small molecule drug Trazodone Hydrochloride: HTR2A, HTR2C, and SLC6A4. Trazodone Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%trazodone hydrochloride%" OR LOWER(tradeNames_string) LIKE "%trazodo...
[{'UUID': 'DrugGeneTargets_v2_4975', 'drugName': 'Trazodone Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HTR2A (ENSG00000102468), HTR2C (ENSG00000147246), SLC6A4 (ENSG00000108576)', 'yearOfFirstApproval': 1981, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGene...
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Q59.206
Q59
What is the genetic target of the small molecule drug Alclometasone Dipropionate, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Alclometasone Dipropionate is NR3C1. Alclometasone Dipropionate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%alclometasone dipropionate%" OR LOWER(tradeNames_string) LIKE "%alcl...
[{'UUID': 'DrugGeneTargets_v2_2070', 'drugName': 'Alclometasone Dipropionate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C1 (ENSG00000113580)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1571
Q59
What is the genetic target of the small molecule drug Gaboxadol, and what is its status in clinical trials and FDA approval?
There are 9 genetic targets of the small molecule drug Gaboxadol: GABRA1, GABRB2, GABRB3, GABRA4, GABRA3, GABRB1, GABRA2, GABRA5, and GABRA6. Gaboxadol reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%gaboxadol%" OR LOWER(tradeNames_string) LIKE "%gaboxadol%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_3615', 'drugName': 'Gaboxadol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GABRA1 (ENSG00000022355), GABRB2 (ENSG00000145864), GABRB3 (ENSG00000166206), GABRA4 (ENSG00000109158), GABRA3 (ENSG00000011677), GABRB1 (ENSG00000163288), GABRA2 (ENSG00000151834), GABRA5 (E...
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Q59.1641
Q59
What is the genetic target of the small molecule drug Iloperidone, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Iloperidone: DRD2 and HTR2A. Iloperidone reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%iloperidone%" OR LOWER(tradeNames_string) LIKE "%iloperidone%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_4312', 'drugName': 'Iloperidone', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD2 (ENSG00000149295), HTR2A (ENSG00000102468)', 'yearOfFirstApproval': 2009, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4313', 'drugName': 'Iloperid...
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Q59.1565
Q59
What is the genetic target of the small molecule drug Azilsartan Medoxomil, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Azilsartan Medoxomil is AGTR1. Azilsartan Medoxomil reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%azilsartan medoxomil%" OR LOWER(tradeNames_string) LIKE "%azilsartan...
[{'UUID': 'DrugGeneTargets_v2_5498', 'drugName': 'Azilsartan Medoxomil', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'AGTR1 (ENSG00000144891)', 'yearOfFirstApproval': 2011, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1209', 'drugName': 'Azilsartan Kamedoxomil'...
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Q59.491
Q59
What is the genetic target of the small molecule drug Sr16234, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Sr16234 is ESR1. Sr16234 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%sr16234%" OR LOWER(tradeNames_string) LIKE "%sr16234%" OR LOWER(drug...
[{'UUID': 'DrugGeneTargets_v2_534', 'drugName': 'Sr16234', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ESR1 (ENSG00000091831)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_5832', 'drugName': 'Sr16234', 'drugMolecularType': 'Small mo...
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Q59.1966
Q59
What is the genetic target of the small molecule drug Sunitinib Malate, and what is its status in clinical trials and FDA approval?
There are 9 genetic targets of the small molecule drug Sunitinib Malate: PDGFRB, PDGFRA, RET, FLT1, FLT4, KDR, CSF1R, FLT3, and KIT. Sunitinib Malate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%sunitinib malate%" OR LOWER(tradeNames_string) LIKE "%sunitinib mala...
[{'UUID': 'DrugGeneTargets_v2_3923', 'drugName': 'Sunitinib Malate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PDGFRB (ENSG00000113721), PDGFRA (ENSG00000134853), RET (ENSG00000165731), FLT1 (ENSG00000102755), FLT4 (ENSG00000037280), KDR (ENSG00000128052), CSF1R (ENSG00000182578), FLT3 (ENSG000...
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Q59.1800
Q59
What is the genetic target of the small molecule drug Debrisoquin, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Debrisoquin is SLC6A2. Debrisoquin reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%debrisoquin%" OR LOWER(tradeNames_string) LIKE "%debrisoquin%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_964', 'drugName': 'Debrisoquin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A2 (ENSG00000103546)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1330
Q59
What is the genetic target of the small molecule drug Miglitol, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Miglitol: MGAM and GAA. Miglitol reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%miglitol%" OR LOWER(tradeNames_string) LIKE "%miglitol%" OR LOWER(dr...
[{'UUID': 'DrugGeneTargets_v2_1114', 'drugName': 'Miglitol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MGAM (ENSG00000257335), GAA (ENSG00000171298)', 'yearOfFirstApproval': 1996, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1115', 'drugName': 'Miglitol', 'd...
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Q59.285
Q59
What is the genetic target of the small molecule drug Amitriptyline, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Amitriptyline: SLC6A2 and SLC6A4. Amitriptyline reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%amitriptyline%" OR LOWER(tradeNames_string) LIKE "%amitriptyline%" O...
[{'UUID': 'DrugGeneTargets_v2_598', 'drugName': 'Nortriptyline', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A4 (ENSG00000108576), SLC6A2 (ENSG00000103546)', 'yearOfFirstApproval': 1964, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1624', 'drugName': 'Amit...
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Q59.1375
Q59
What is the genetic target of the small molecule drug Echothiophate, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Echothiophate is ACHE. Echothiophate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%echothiophate%" OR LOWER(tradeNames_string) LIKE "%echothiophate%" O...
[{'UUID': 'DrugGeneTargets_v2_2260', 'drugName': 'Echothiophate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ACHE (ENSG00000087085)', 'yearOfFirstApproval': 1960, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2129', 'drugName': 'Echothiophate Iodide', 'drugMol...
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Q59.221
Q59
What is the genetic target of the small molecule drug Copanlisib, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Copanlisib: PIK3CA and PIK3CD. Copanlisib reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%copanlisib%" OR LOWER(tradeNames_string) LIKE "%copanlisib%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_2314', 'drugName': 'Copanlisib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PIK3CA (ENSG00000121879), PIK3CD (ENSG00000171608)', 'yearOfFirstApproval': 2017, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2313', 'drugName': 'Copanl...
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Q59.1931
Q59
What is the genetic target of the small molecule drug Revefenacin, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Revefenacin is CHRM3. Revefenacin reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%revefenacin%" OR LOWER(tradeNames_string) LIKE "%revefenacin%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_4223', 'drugName': 'Revefenacin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM3 (ENSG00000133019)', 'yearOfFirstApproval': 2018, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.888
Q59
What is the genetic target of the small molecule drug Fomepizole, and what is its status in clinical trials and FDA approval?
There are 3 genetic targets of the small molecule drug Fomepizole: ADH1A, ADH1B, and ADH1C. Fomepizole reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%fomepizole%" OR LOWER(tradeNames_string) LIKE "%fomepizole%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_1663', 'drugName': 'Fomepizole', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADH1A (ENSG00000187758), ADH1B (ENSG00000196616), ADH1C (ENSG00000248144)', 'yearOfFirstApproval': 1997, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1623
Q59
What is the genetic target of the small molecule drug Latanoprostene Bunod, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Latanoprostene Bunod is PTGFR. Latanoprostene Bunod reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%latanoprostene bunod%" OR LOWER(tradeNames_string) LIKE "%latanopros...
[{'UUID': 'DrugGeneTargets_v2_2312', 'drugName': 'Latanoprostene Bunod', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGFR (ENSG00000122420)', 'yearOfFirstApproval': 2017, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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