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Q59.1464
Q59
What is the genetic target of the small molecule drug Etonogestrel, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Etonogestrel is PGR. Etonogestrel reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%etonogestrel%" OR LOWER(tradeNames_string) LIKE "%etonogestrel%" OR ...
[{'UUID': 'DrugGeneTargets_v2_6181', 'drugName': 'Etonogestrel', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PGR (ENSG00000082175)', 'yearOfFirstApproval': 2001, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1556
Q59
What is the genetic target of the small molecule drug Cabozantinib S-Malate, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Cabozantinib S-Malate: MET and KDR. Cabozantinib S-Malate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%cabozantinib s-malate%" OR LOWER(tradeNames_string) LIKE "%cabozanti...
[{'UUID': 'DrugGeneTargets_v2_3579', 'drugName': 'Cabozantinib S-Malate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MET (ENSG00000105976), KDR (ENSG00000128052)', 'yearOfFirstApproval': 2012, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3580', 'drugName': 'C...
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Q59.708
Q59
What is the genetic target of the small molecule drug Diphenidol, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Diphenidol is CHRM1. Diphenidol reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%diphenidol%" OR LOWER(tradeNames_string) LIKE "%diphenidol%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_1476', 'drugName': 'Diphenidol Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM1 (ENSG00000168539)', 'yearOfFirstApproval': 1967, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4667', 'drugName': 'Diphenidol', 'drugM...
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Q59.1928
Q59
What is the genetic target of the small molecule drug Carbinoxamine, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Carbinoxamine is HRH1. Carbinoxamine reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%carbinoxamine%" OR LOWER(tradeNames_string) LIKE "%carbinoxamine%" O...
[{'UUID': 'DrugGeneTargets_v2_4593', 'drugName': 'Carbinoxamine Maleate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 2003, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1625', 'drugName': 'Carbinoxamine', 'drugMo...
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Q59.614
Q59
What is the genetic target of the small molecule drug Ibandronate Sodium, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Ibandronate Sodium is FDPS. Ibandronate Sodium reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%ibandronate sodium%" OR LOWER(tradeNames_string) LIKE "%ibandronate ...
[{'UUID': 'DrugGeneTargets_v2_2230', 'drugName': 'Ibandronate Sodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'FDPS (ENSG00000160752)', 'yearOfFirstApproval': 2003, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.372
Q59
What is the genetic target of the small molecule drug Varlitinib, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Varlitinib: ERBB2 and EGFR. Varlitinib reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%varlitinib%" OR LOWER(tradeNames_string) LIKE "%varlitinib%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_4435', 'drugName': 'Varlitinib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ERBB2 (ENSG00000141736), EGFR (ENSG00000146648)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_4436', 'drugName': 'Varlitinib'...
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Q59.1756
Q59
What is the genetic target of the small molecule drug Diethylstilbestrol, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Diethylstilbestrol is ESR1. Diethylstilbestrol reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%diethylstilbestrol%" OR LOWER(tradeNames_string) LIKE "%diethylstilb...
[{'UUID': 'DrugGeneTargets_v2_4689', 'drugName': 'Diethylstilbestrol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ESR1 (ENSG00000091831)', 'yearOfFirstApproval': 1973, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4127', 'drugName': 'Diethylstilbestrol Diphosp...
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Q59.1669
Q59
What is the genetic target of the small molecule drug Jnj-42165279, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Jnj-42165279 is FAAH. Jnj-42165279 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%jnj-42165279%" OR LOWER(tradeNames_string) LIKE "%jnj-42165279%" OR ...
[{'UUID': 'DrugGeneTargets_v2_5455', 'drugName': 'Jnj-42165279', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'FAAH (ENSG00000117480)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.533
Q59
What is the genetic target of the small molecule drug Montelukast Sodium, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Montelukast Sodium is CYSLTR1. Montelukast Sodium reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%montelukast sodium%" OR LOWER(tradeNames_string) LIKE "%montelukast ...
[{'UUID': 'DrugGeneTargets_v2_2453', 'drugName': 'Montelukast Sodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CYSLTR1 (ENSG00000173198)', 'yearOfFirstApproval': 1998, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1821
Q59
What is the genetic target of the small molecule drug Caffeine, and what is its status in clinical trials and FDA approval?
There are 4 genetic targets of the small molecule drug Caffeine: ADORA1, ADORA2B, ADORA3, and ADORA2A. Caffeine reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%caffeine%" OR LOWER(tradeNames_string) LIKE "%caffeine%" OR LOWER(dr...
[{'UUID': 'DrugGeneTargets_v2_4744', 'drugName': 'Caffeine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADORA1 (ENSG00000163485), ADORA2B (ENSG00000170425), ADORA3 (ENSG00000282608), ADORA2A (ENSG00000128271)', 'yearOfFirstApproval': 1948, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'U...
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Q59.1442
Q59
What is the genetic target of the small molecule drug Cannabidiol, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Cannabidiol is CNR1. Cannabidiol reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%cannabidiol%" OR LOWER(tradeNames_string) LIKE "%cannabidiol%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_4055', 'drugName': 'Cannabidiol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CNR1 (ENSG00000118432)', 'yearOfFirstApproval': 2018, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.302
Q59
What is the genetic target of the small molecule drug Pergolide Mesylate, and what is its status in clinical trials and FDA approval?
There are 5 genetic targets of the small molecule drug Pergolide Mesylate: DRD2, DRD3, DRD5, DRD4, and DRD1. Pergolide Mesylate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%pergolide mesylate%" OR LOWER(tradeNames_string) LIKE "%pergolide me...
[{'UUID': 'DrugGeneTargets_v2_6076', 'drugName': 'Pergolide Mesylate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD2 (ENSG00000149295), DRD3 (ENSG00000151577), DRD5 (ENSG00000169676), DRD4 (ENSG00000069696), DRD1 (ENSG00000184845)', 'yearOfFirstApproval': 1988, 'maxClinicalTrialPhase': 4, 'dru...
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Q59.1016
Q59
What is the genetic target of the oligosaccharide drug Fondaparinux, and what is its status in clinical trials and FDA approval?
The genetic target of the oligosaccharide drug Fondaparinux is SERPINC1. Fondaparinux reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%fondaparinux%" OR LOWER(tradeNames_string) LIKE "%fondaparinux%" OR ...
[{'UUID': 'DrugGeneTargets_v2_1957', 'drugName': 'Fondaparinux Sodium', 'drugMolecularType': 'Oligosaccharide', 'newLinkedTargets_string': 'SERPINC1 (ENSG00000117601)', 'yearOfFirstApproval': 2001, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1756', 'drugName': 'Fondaparinux', 'drug...
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Q59.1417
Q59
What is the genetic target of the antibody drug Talquetamab, and what is its status in clinical trials and FDA approval?
There are 4 genetic targets of the antibody drug Talquetamab: GPRC5D, CD3E, CD3G, and CD3D. Talquetamab reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%talquetamab%" OR LOWER(tradeNames_string) LIKE "%talquetamab%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_5924', 'drugName': 'Talquetamab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'GPRC5D (ENSG00000111291), CD3E (ENSG00000198851), CD3G (ENSG00000160654), CD3D (ENSG00000167286)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}, {'UUID': 'DrugGe...
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Q59.1567
Q59
What is the genetic target of the oligonucleotide drug Custirsen, and what is its status in clinical trials and FDA approval?
The genetic target of the oligonucleotide drug Custirsen is CLU. Custirsen reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%custirsen%" OR LOWER(tradeNames_string) LIKE "%custirsen%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_2223', 'drugName': 'Custirsen Sodium', 'drugMolecularType': 'Oligonucleotide', 'newLinkedTargets_string': 'CLU (ENSG00000120885)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_5297', 'drugName': 'Custirsen', 'drugMolecularType...
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Q59.1311
Q59
What is the genetic target of the protein drug Octreotide, and what is its status in clinical trials and FDA approval?
There are 5 genetic targets of the protein drug Octreotide: SSTR5, SSTR2, SSTR4, SSTR1, and SSTR3. Octreotide reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%octreotide%" OR LOWER(tradeNames_string) LIKE "%octreotide%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_759', 'drugName': 'Octreotide Acetate', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'SSTR5 (ENSG00000162009), SSTR2 (ENSG00000180616), SSTR4 (ENSG00000132671), SSTR1 (ENSG00000139874), SSTR3 (ENSG00000278195)', 'yearOfFirstApproval': 1988, 'maxClinicalTrialPhase': 4, 'drugIs...
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Q59.862
Q59
What is the genetic target of the small molecule drug Benoxinate Hydrochloride, and what is its status in clinical trials and FDA approval?
There are 10 genetic targets of the small molecule drug Benoxinate Hydrochloride: SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. Benoxinate Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%benoxinate hydrochloride%" OR LOWER(tradeNames_string) LIKE "%benoxi...
[{'UUID': 'DrugGeneTargets_v2_2819', 'drugName': 'Benoxinate Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SCN1A (ENSG00000144285), SCN5A (ENSG00000183873), SCN4A (ENSG00000007314), SCN7A (ENSG00000136546), SCN2A (ENSG00000136531), SCN9A (ENSG00000169432), SCN3A (ENSG00000153253), S...
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Q59.591
Q59
What is the genetic target of the small molecule drug Pimasertib, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Pimasertib: MAP2K1 and MAP2K2. Pimasertib reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%pimasertib%" OR LOWER(tradeNames_string) LIKE "%pimasertib%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_3059', 'drugName': 'Pimasertib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MAP2K1 (ENSG00000169032), MAP2K2 (ENSG00000126934)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_3060', 'drugName': 'Pimasert...
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Q59.485
Q59
What is the genetic target of the small molecule drug Ambrisentan, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Ambrisentan: EDNRB and EDNRA. Ambrisentan reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%ambrisentan%" OR LOWER(tradeNames_string) LIKE "%ambrisentan%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_3910', 'drugName': 'Ambrisentan', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'EDNRB (ENSG00000136160), EDNRA (ENSG00000151617)', 'yearOfFirstApproval': 2007, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1473
Q59
What is the genetic target of the small molecule drug Bfh-772, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Bfh-772 is KDR. Bfh-772 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%bfh-772%" OR LOWER(tradeNames_string) LIKE "%bfh-772%" OR LOWER(drug...
[{'UUID': 'DrugGeneTargets_v2_2209', 'drugName': 'Bfh-772', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'KDR (ENSG00000128052)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.1784
Q59
What is the genetic target of the antibody drug Ravagalimab, and what is its status in clinical trials and FDA approval?
The genetic target of the antibody drug Ravagalimab is CD40LG. Ravagalimab reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%ravagalimab%" OR LOWER(tradeNames_string) LIKE "%ravagalimab%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_5736', 'drugName': 'Ravagalimab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'CD40LG (ENSG00000102245)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.644
Q59
What is the genetic target of the protein drug Trenibotulinumtoxine, and what is its status in clinical trials and FDA approval?
The genetic target of the protein drug Trenibotulinumtoxine is SNAP25. Trenibotulinumtoxine reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%trenibotulinumtoxine%" OR LOWER(tradeNames_string) LIKE "%trenibotul...
[{'UUID': 'DrugGeneTargets_v2_2986', 'drugName': 'Trenibotulinumtoxine', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'SNAP25 (ENSG00000132639)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.357
Q59
What is the genetic target of the antibody drug Vixarelimab, and what is its status in clinical trials and FDA approval?
The genetic target of the antibody drug Vixarelimab is OSMR. Vixarelimab reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%vixarelimab%" OR LOWER(tradeNames_string) LIKE "%vixarelimab%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_3110', 'drugName': 'Vixarelimab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'OSMR (ENSG00000145623)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.1128
Q59
What is the genetic target of the small molecule drug Doxycycline Hyclate, and what is its status in clinical trials and FDA approval?
There are 4 genetic targets of the small molecule drug Doxycycline Hyclate: MMP13, MMP1, MMP7, and MMP8. Doxycycline Hyclate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%doxycycline hyclate%" OR LOWER(tradeNames_string) LIKE "%doxycycline...
[{'UUID': 'DrugGeneTargets_v2_2400', 'drugName': 'Doxycycline Hyclate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MMP13 (ENSG00000137745), MMP1 (ENSG00000196611), MMP7 (ENSG00000137673), MMP8 (ENSG00000118113)', 'yearOfFirstApproval': 1967, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {...
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Q59.439
Q59
What is the genetic target of the small molecule drug Pomalidomide, and what is its status in clinical trials and FDA approval?
There are 4 genetic targets of the small molecule drug Pomalidomide: CRBN, DDB1, CUL4A, and RBX1. Pomalidomide reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%pomalidomide%" OR LOWER(tradeNames_string) LIKE "%pomalidomide%" OR ...
[{'UUID': 'DrugGeneTargets_v2_4886', 'drugName': 'Pomalidomide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CRBN (ENSG00000113851), DDB1 (ENSG00000167986), CUL4A (ENSG00000139842), RBX1 (ENSG00000100387)', 'yearOfFirstApproval': 2013, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1121
Q59
What is the genetic target of the small molecule drug Thiethylperazine Maleate, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Thiethylperazine Maleate is DRD2. Thiethylperazine Maleate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%thiethylperazine maleate%" OR LOWER(tradeNames_string) LIKE "%thieth...
[{'UUID': 'DrugGeneTargets_v2_101', 'drugName': 'Thiethylperazine Maleate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD2 (ENSG00000149295)', 'yearOfFirstApproval': 1961, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1103
Q59
What is the genetic target of the small molecule drug Belumosudil Mesylate, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Belumosudil Mesylate: ROCK2 and ROCK1. Belumosudil Mesylate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%belumosudil mesylate%" OR LOWER(tradeNames_string) LIKE "%belumosudi...
[{'UUID': 'DrugGeneTargets_v2_6300', 'drugName': 'Belumosudil Mesylate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ROCK2 (ENSG00000134318), ROCK1 (ENSG00000067900)', 'yearOfFirstApproval': 2021, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1348
Q59
What is the genetic target of the small molecule drug Haloperidol Decanoate, and what is its status in clinical trials and FDA approval?
There are 4 genetic targets of the small molecule drug Haloperidol Decanoate: DRD2, DRD3, DRD4, and HTR2A. Haloperidol Decanoate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%haloperidol decanoate%" OR LOWER(tradeNames_string) LIKE "%haloperid...
[{'UUID': 'DrugGeneTargets_v2_5257', 'drugName': 'Haloperidol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD2 (ENSG00000149295), DRD3 (ENSG00000151577), DRD4 (ENSG00000069696), HTR2A (ENSG00000102468)', 'yearOfFirstApproval': 1967, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': ...
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Q59.597
Q59
What is the genetic target of the small molecule drug Azd1446, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Azd1446: CHRNB2 and CHRNA4. Azd1446 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%azd1446%" OR LOWER(tradeNames_string) LIKE "%azd1446%" OR LOWER(drug...
[{'UUID': 'DrugGeneTargets_v2_4875', 'drugName': 'Azd1446', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRNB2 (ENSG00000160716), CHRNA4 (ENSG00000101204)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.1368
Q59
What is the genetic target of the protein drug Abarelix, and what is its status in clinical trials and FDA approval?
The genetic target of the protein drug Abarelix is GNRHR. Abarelix reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%abarelix%" OR LOWER(tradeNames_string) LIKE "%abarelix%" OR LOWER(dr...
[{'UUID': 'DrugGeneTargets_v2_4834', 'drugName': 'Abarelix', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'GNRHR (ENSG00000109163)', 'yearOfFirstApproval': 2003, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1401
Q59
What is the genetic target of the small molecule drug Oxybutynin, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Oxybutynin: CHRM3 and CHRM2. Oxybutynin reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%oxybutynin%" OR LOWER(tradeNames_string) LIKE "%oxybutynin%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_3', 'drugName': 'Oxybutynin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM3 (ENSG00000133019), CHRM2 (ENSG00000181072)', 'yearOfFirstApproval': 1975, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2', 'drugName': 'Oxybutynin', '...
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Q59.753
Q59
What is the genetic target of the small molecule drug Cep-37440, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Cep-37440: ALK and PTK2. Cep-37440 reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%cep-37440%" OR LOWER(tradeNames_string) LIKE "%cep-37440%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_4475', 'drugName': 'Cep-37440', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ALK (ENSG00000171094), PTK2 (ENSG00000169398)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_4476', 'drugName': 'Cep-37440', 'd...
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Q59.259
Q59
What is the genetic target of the antibody drug Bimagrumab, and what is its status in clinical trials and FDA approval?
The genetic target of the antibody drug Bimagrumab is ACVR2B. Bimagrumab reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%bimagrumab%" OR LOWER(tradeNames_string) LIKE "%bimagrumab%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_299', 'drugName': 'Bimagrumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'ACVR2B (ENSG00000114739)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}]
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Q59.1687
Q59
What is the genetic target of the antibody drug Fazpilodemab, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the antibody drug Fazpilodemab: FGF1 and KLB. Fazpilodemab reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%fazpilodemab%" OR LOWER(tradeNames_string) LIKE "%fazpilodemab%" OR ...
[{'UUID': 'DrugGeneTargets_v2_1258', 'drugName': 'Fazpilodemab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'FGF1 (ENSG00000113578), KLB (ENSG00000134962)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.1723
Q59
What is the genetic target of the antibody drug Ozanezumab, and what is its status in clinical trials and FDA approval?
The genetic target of the antibody drug Ozanezumab is RTN4. Ozanezumab reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%ozanezumab%" OR LOWER(tradeNames_string) LIKE "%ozanezumab%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_6319', 'drugName': 'Ozanezumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'RTN4 (ENSG00000115310)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.544
Q59
What is the genetic target of the small molecule drug Arsenic Trioxide, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Arsenic Trioxide is TXNRD1. Arsenic Trioxide reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%arsenic trioxide%" OR LOWER(tradeNames_string) LIKE "%arsenic trioxi...
[{'UUID': 'DrugGeneTargets_v2_975', 'drugName': 'Arsenic Trioxide', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TXNRD1 (ENSG00000198431)', 'yearOfFirstApproval': 2000, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.792
Q59
What is the genetic target of the small molecule drug Edasalonexent, and what is its status in clinical trials and FDA approval?
There are 3 genetic targets of the small molecule drug Edasalonexent: NFKB2, NFKB1, and RELA. Edasalonexent reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%edasalonexent%" OR LOWER(tradeNames_string) LIKE "%edasalonexent%" O...
[{'UUID': 'DrugGeneTargets_v2_1568', 'drugName': 'Edasalonexent', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NFKB2 (ENSG00000077150), NFKB1 (ENSG00000109320), RELA (ENSG00000173039)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}]
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Q59.1484
Q59
What is the genetic target of the protein drug Histrelin Acetate, and what is its status in clinical trials and FDA approval?
The genetic target of the protein drug Histrelin Acetate is GNRHR. Histrelin Acetate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%histrelin acetate%" OR LOWER(tradeNames_string) LIKE "%histrelin ace...
[{'UUID': 'DrugGeneTargets_v2_3420', 'drugName': 'Histrelin Acetate', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'GNRHR (ENSG00000109163)', 'yearOfFirstApproval': 1991, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.420
Q59
What is the genetic target of the antibody drug Vantictumab, and what is its status in clinical trials and FDA approval?
There are 5 genetic targets of the antibody drug Vantictumab: FZD2, FZD7, FZD1, FZD5, and FZD8. Vantictumab reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%vantictumab%" OR LOWER(tradeNames_string) LIKE "%vantictumab%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_5828', 'drugName': 'Vantictumab', 'drugMolecularType': 'Antibody', 'newLinkedTargets_string': 'FZD2 (ENSG00000180340), FZD7 (ENSG00000155760), FZD1 (ENSG00000157240), FZD5 (ENSG00000163251), FZD8 (ENSG00000177283)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': Fa...
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Q59.1849
Q59
What is the genetic target of the small molecule drug Venlafaxine, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Venlafaxine: SLC6A4 and SLC6A2. Venlafaxine reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%venlafaxine%" OR LOWER(tradeNames_string) LIKE "%venlafaxine%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_1438', 'drugName': 'Desvenlafaxine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A2 (ENSG00000103546), SLC6A4 (ENSG00000108576)', 'yearOfFirstApproval': 2008, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5873', 'drugName': 'De...
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Q59.1920
Q59
What is the genetic target of the small molecule drug Pantoprazole, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Pantoprazole: ATP4A and ATP4B. Pantoprazole reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%pantoprazole%" OR LOWER(tradeNames_string) LIKE "%pantoprazole%" OR ...
[{'UUID': 'DrugGeneTargets_v2_1903', 'drugName': 'Pantoprazole Sodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ATP4A (ENSG00000105675), ATP4B (ENSG00000186009)', 'yearOfFirstApproval': 2000, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4835', 'drugName': ...
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Q59.1099
Q59
What is the genetic target of the protein drug Pegvisomant, and what is its status in clinical trials and FDA approval?
The genetic target of the protein drug Pegvisomant is GHR. Pegvisomant reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%pegvisomant%" OR LOWER(tradeNames_string) LIKE "%pegvisomant%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_1805', 'drugName': 'Pegvisomant', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'GHR (ENSG00000112964)', 'yearOfFirstApproval': 2003, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.845
Q59
What is the genetic target of the small molecule drug Canrenone, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Canrenone is NR3C2. Canrenone reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%canrenone%" OR LOWER(tradeNames_string) LIKE "%canrenone%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_82', 'drugName': 'Canrenoate Potassium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C2 (ENSG00000151623)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4514', 'drugName': 'Canrenone', 'drugMolecularTy...
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Q59.68
Q59
What is the genetic target of the small molecule drug Mardepodect, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Mardepodect is PDE10A. Mardepodect reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%mardepodect%" OR LOWER(tradeNames_string) LIKE "%mardepodect%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_4386', 'drugName': 'Mardepodect', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PDE10A (ENSG00000112541)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.1698
Q59
What is the genetic target of the small molecule drug Nandrolone Decanoate, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Nandrolone Decanoate is AR. Nandrolone Decanoate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%nandrolone decanoate%" OR LOWER(tradeNames_string) LIKE "%nandrolone...
[{'UUID': 'DrugGeneTargets_v2_5812', 'drugName': 'Nandrolone Decanoate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'AR (ENSG00000169083)', 'yearOfFirstApproval': 1983, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1733
Q59
What is the genetic target of the small molecule drug Glafenine, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Glafenine: PTGS2 and PTGS1. Glafenine reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%glafenine%" OR LOWER(tradeNames_string) LIKE "%glafenine%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_579', 'drugName': 'Glafenine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGS2 (ENSG00000073756), PTGS1 (ENSG00000095303)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.380
Q59
What is the genetic target of the small molecule drug Fosnetupitant Chloride Hydrochloride, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Fosnetupitant Chloride Hydrochloride is TACR1. Fosnetupitant Chloride Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%fosnetupitant chloride hydrochloride%" OR LOWER(tradeNames_string) L...
[{'UUID': 'DrugGeneTargets_v2_4376', 'drugName': 'Fosnetupitant Chloride Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TACR1 (ENSG00000115353)', 'yearOfFirstApproval': 2018, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.240
Q59
What is the genetic target of the small molecule drug Sotalol Hydrochloride, and what is its status in clinical trials and FDA approval?
There are 3 genetic targets of the small molecule drug Sotalol Hydrochloride: ADRB1, KCNH2, and ADRB2. Sotalol Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%sotalol hydrochloride%" OR LOWER(tradeNames_string) LIKE "%sotalol h...
[{'UUID': 'DrugGeneTargets_v2_4569', 'drugName': 'Sotalol Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB1 (ENSG00000043591), KCNH2 (ENSG00000055118), ADRB2 (ENSG00000169252)', 'yearOfFirstApproval': 1992, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTar...
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Q59.257
Q59
What is the genetic target of the small molecule drug Prasugrel, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Prasugrel is P2RY12. Prasugrel reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%prasugrel%" OR LOWER(tradeNames_string) LIKE "%prasugrel%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_2823', 'drugName': 'Prasugrel Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'P2RY12 (ENSG00000169313)', 'yearOfFirstApproval': 2009, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3169', 'drugName': 'Prasugrel', 'drugMo...
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Q59.1032
Q59
What is the genetic target of the small molecule drug Laropiprant, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Laropiprant is PTGDR. Laropiprant reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%laropiprant%" OR LOWER(tradeNames_string) LIKE "%laropiprant%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_1831', 'drugName': 'Laropiprant', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PTGDR (ENSG00000168229)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.30
Q59
What is the genetic target of the small molecule drug Acrivastine, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Acrivastine is HRH1. Acrivastine reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%acrivastine%" OR LOWER(tradeNames_string) LIKE "%acrivastine%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_2524', 'drugName': 'Acrivastine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 1994, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.293
Q59
What is the genetic target of the small molecule drug Omeprazole Magnesium, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Omeprazole Magnesium: ATP4A and ATP4B. Omeprazole Magnesium reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%omeprazole magnesium%" OR LOWER(tradeNames_string) LIKE "%omeprazole...
[{'UUID': 'DrugGeneTargets_v2_4440', 'drugName': 'Esomeprazole Magnesium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ATP4A (ENSG00000105675), ATP4B (ENSG00000186009)', 'yearOfFirstApproval': 2001, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3369', 'drugName...
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Q59.1886
Q59
What is the genetic target of the small molecule drug Pg-760564, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Pg-760564 is MAPK14. Pg-760564 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%pg-760564%" OR LOWER(tradeNames_string) LIKE "%pg-760564%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_2205', 'drugName': 'Pg-760564', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'MAPK14 (ENSG00000112062)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.1823
Q59
What is the genetic target of the small molecule drug Fluoxetine, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Fluoxetine is SLC6A4. Fluoxetine reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%fluoxetine%" OR LOWER(tradeNames_string) LIKE "%fluoxetine%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_4711', 'drugName': 'Fluoxetine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A4 (ENSG00000108576)', 'yearOfFirstApproval': 1987, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4447', 'drugName': 'Fluoxetine', 'drug...
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Q59.620
Q59
What is the genetic target of the small molecule drug Esketamine Hydrochloride, and what is its status in clinical trials and FDA approval?
There are 7 genetic targets of the small molecule drug Esketamine Hydrochloride: GRIN1, GRIN2A, GRIN2B, GRIN2D, GRIN3B, GRIN2C, and GRIN3A. Esketamine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%esketamine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%esketa...
[{'UUID': 'DrugGeneTargets_v2_817', 'drugName': 'Esketamine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'GRIN1 (ENSG00000176884), GRIN2A (ENSG00000183454), GRIN2B (ENSG00000273079), GRIN2D (ENSG00000105464), GRIN3B (ENSG00000116032), GRIN2C (ENSG00000161509), GRIN3A (ENSG0000019878...
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Q59.1667
Q59
What is the genetic target of the small molecule drug Forodesine Hydrochloride, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Forodesine Hydrochloride is PNP. Forodesine Hydrochloride reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%forodesine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%forode...
[{'UUID': 'DrugGeneTargets_v2_5700', 'drugName': 'Forodesine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PNP (ENSG00000198805)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.850
Q59
What is the genetic target of the small molecule drug Apomorphine, and what is its status in clinical trials and FDA approval?
There are 3 genetic targets of the small molecule drug Apomorphine: DRD2, DRD3, and DRD4. Apomorphine reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%apomorphine%" OR LOWER(tradeNames_string) LIKE "%apomorphine%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_3259', 'drugName': 'Apomorphine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD2 (ENSG00000149295), DRD3 (ENSG00000151577), DRD4 (ENSG00000069696)', 'yearOfFirstApproval': 2004, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3300'...
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Q59.215
Q59
What is the genetic target of the protein drug Setmelanotide, and what is its status in clinical trials and FDA approval?
The genetic target of the protein drug Setmelanotide is MC4R. Setmelanotide reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%setmelanotide%" OR LOWER(tradeNames_string) LIKE "%setmelanotide%" O...
[{'UUID': 'DrugGeneTargets_v2_689', 'drugName': 'Setmelanotide', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'MC4R (ENSG00000166603)', 'yearOfFirstApproval': 2020, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2878', 'drugName': 'Setmelanotide Acetate', 'drugMolecularT...
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Q59.524
Q59
What is the genetic target of the small molecule drug Fluphenazine, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Fluphenazine is DRD2. Fluphenazine reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%fluphenazine%" OR LOWER(tradeNames_string) LIKE "%fluphenazine%" OR ...
[{'UUID': 'DrugGeneTargets_v2_905', 'drugName': 'Fluphenazine Enanthate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD2 (ENSG00000149295)', 'yearOfFirstApproval': 1967, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4664', 'drugName': 'Fluphenazine', 'drugMol...
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Q59.477
Q59
What is the genetic target of the small molecule drug Irinotecan, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Irinotecan is TOP1. Irinotecan reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%irinotecan%" OR LOWER(tradeNames_string) LIKE "%irinotecan%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_5193', 'drugName': 'Irinotecan Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TOP1 (ENSG00000198900)', 'yearOfFirstApproval': 1996, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_4299', 'drugName': 'Irinotecan', 'drugMo...
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Q59.1327
Q59
What is the genetic target of the small molecule drug Biperiden Lactate, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Biperiden Lactate is CHRM1. Biperiden Lactate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%biperiden lactate%" OR LOWER(tradeNames_string) LIKE "%biperiden lac...
[{'UUID': 'DrugGeneTargets_v2_6214', 'drugName': 'Biperiden Lactate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM1 (ENSG00000168539)', 'yearOfFirstApproval': 1961, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1433
Q59
What is the genetic target of the small molecule drug Phenylephrine Bitartrate, and what is its status in clinical trials and FDA approval?
There are 3 genetic targets of the small molecule drug Phenylephrine Bitartrate: ADRA1A, ADRA1D, and ADRA1B. Phenylephrine Bitartrate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%phenylephrine bitartrate%" OR LOWER(tradeNames_string) LIKE "%phenyl...
[{'UUID': 'DrugGeneTargets_v2_2414', 'drugName': 'Phenylephrine Bitartrate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRA1A (ENSG00000120907), ADRA1D (ENSG00000171873), ADRA1B (ENSG00000170214)', 'yearOfFirstApproval': 1973, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.123
Q59
What is the genetic target of the small molecule drug Dimethindene, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Dimethindene is HRH1. Dimethindene reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%dimethindene%" OR LOWER(tradeNames_string) LIKE "%dimethindene%" OR ...
[{'UUID': 'DrugGeneTargets_v2_588', 'drugName': 'Dimethindene', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1351
Q59
What is the genetic target of the small molecule drug Ccx354, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Ccx354 is CCR1. Ccx354 reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%ccx354%" OR LOWER(tradeNames_string) LIKE "%ccx354%" OR LOWER(drugSy...
[{'UUID': 'DrugGeneTargets_v2_200', 'drugName': 'Ccx354', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CCR1 (ENSG00000163823)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.1942
Q59
What is the genetic target of the small molecule drug Mavelertinib, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Mavelertinib is EGFR. Mavelertinib reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%mavelertinib%" OR LOWER(tradeNames_string) LIKE "%mavelertinib%" OR ...
[{'UUID': 'DrugGeneTargets_v2_6168', 'drugName': 'Mavelertinib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'EGFR (ENSG00000146648)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.1371
Q59
What is the genetic target of the small molecule drug Doxepin Hydrochloride, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Doxepin Hydrochloride is SLC6A2. Doxepin Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%doxepin hydrochloride%" OR LOWER(tradeNames_string) LIKE "%doxepin h...
[{'UUID': 'DrugGeneTargets_v2_2495', 'drugName': 'Doxepin Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A2 (ENSG00000103546)', 'yearOfFirstApproval': 1969, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1171
Q59
What is the genetic target of the small molecule drug Ranitidine Hydrochloride, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Ranitidine Hydrochloride is HRH2. Ranitidine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%ranitidine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%raniti...
[{'UUID': 'DrugGeneTargets_v2_1617', 'drugName': 'Ranitidine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH2 (ENSG00000113749)', 'yearOfFirstApproval': 1983, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.138
Q59
What is the genetic target of the protein drug Barusiban, and what is its status in clinical trials and FDA approval?
The genetic target of the protein drug Barusiban is OXTR. Barusiban reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%barusiban%" OR LOWER(tradeNames_string) LIKE "%barusiban%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_1521', 'drugName': 'Barusiban', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'OXTR (ENSG00000180914)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.1134
Q59
What is the genetic target of the small molecule drug Telratolimod, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Telratolimod: TLR8 and TLR7. Telratolimod reached phase 1 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%telratolimod%" OR LOWER(tradeNames_string) LIKE "%telratolimod%" OR ...
[{'UUID': 'DrugGeneTargets_v2_5246', 'drugName': 'Telratolimod', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TLR8 (ENSG00000101916), TLR7 (ENSG00000196664)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_5247', 'drugName': 'Telratolim...
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Q59.1874
Q59
What is the genetic target of the small molecule drug Morphine, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Morphine is OPRM1. Morphine reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%morphine%" OR LOWER(tradeNames_string) LIKE "%morphine%" OR LOWER(dr...
[{'UUID': 'DrugGeneTargets_v2_3300', 'drugName': 'Apomorphine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD2 (ENSG00000149295), DRD3 (ENSG00000151577), DRD4 (ENSG00000069696)', 'yearOfFirstApproval': 2004, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTa...
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Q59.1241
Q59
What is the genetic target of the small molecule drug Cisatracurium, and what is its status in clinical trials and FDA approval?
There are 5 genetic targets of the small molecule drug Cisatracurium: CHRNA1, CHRNG, CHRNB1, CHRND, and CHRNE. Cisatracurium reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%cisatracurium%" OR LOWER(tradeNames_string) LIKE "%cisatracurium%" O...
[{'UUID': 'DrugGeneTargets_v2_3167', 'drugName': 'Cisatracurium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRNA1 (ENSG00000138435), CHRNG (ENSG00000196811), CHRNB1 (ENSG00000170175), CHRND (ENSG00000135902), CHRNE (ENSG00000108556)', 'yearOfFirstApproval': 1995, 'maxClinicalTrialPhase': 4, 'd...
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Q59.1338
Q59
What is the genetic target of the small molecule drug Methamphetamine Hydrochloride, and what is its status in clinical trials and FDA approval?
There are 3 genetic targets of the small molecule drug Methamphetamine Hydrochloride: SLC6A4, SLC6A3, and SLC6A2. Methamphetamine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%methamphetamine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%m...
[{'UUID': 'DrugGeneTargets_v2_5557', 'drugName': 'Methamphetamine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A4 (ENSG00000108576), SLC6A3 (ENSG00000142319), SLC6A2 (ENSG00000103546)', 'yearOfFirstApproval': 1943, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.958
Q59
What is the genetic target of the small molecule drug Thioguanine, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Thioguanine: IMPDH1 and IMPDH2. Thioguanine reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%thioguanine%" OR LOWER(tradeNames_string) LIKE "%thioguanine%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_5258', 'drugName': 'Thioguanine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'IMPDH1 (ENSG00000106348), IMPDH2 (ENSG00000178035)', 'yearOfFirstApproval': 1966, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.929
Q59
What is the genetic target of the small molecule drug Trihexyphenidyl, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Trihexyphenidyl is CHRM1. Trihexyphenidyl reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%trihexyphenidyl%" OR LOWER(tradeNames_string) LIKE "%trihexyphenidyl...
[{'UUID': 'DrugGeneTargets_v2_6217', 'drugName': 'Trihexyphenidyl', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRM1 (ENSG00000168539)', 'yearOfFirstApproval': 1949, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_6050', 'drugName': 'Trihexyphenidyl Hydrochlorid...
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Q59.112
Q59
What is the genetic target of the small molecule drug Synthetic Conjugated Estrogens, B, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Synthetic Conjugated Estrogens, B: ESR2 and ESR1. Synthetic Conjugated Estrogens, B reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%synthetic conjugated estrogens, b%" OR LOWER(tradeNames_string) LIKE...
[{'UUID': 'DrugGeneTargets_v2_4209', 'drugName': 'Synthetic Conjugated Estrogens, B', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ESR2 (ENSG00000140009), ESR1 (ENSG00000091831)', 'yearOfFirstApproval': 2004, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1240
Q59
What is the genetic target of the small molecule drug Pentolinium Tartrate, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Pentolinium Tartrate: CHRNB4 and CHRNA3. Pentolinium Tartrate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%pentolinium tartrate%" OR LOWER(tradeNames_string) LIKE "%pentoliniu...
[{'UUID': 'DrugGeneTargets_v2_4468', 'drugName': 'Pentolinium Tartrate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CHRNB4 (ENSG00000117971), CHRNA3 (ENSG00000080644)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1921
Q59
What is the genetic target of the protein drug Ceruletide Diethylamine, and what is its status in clinical trials and FDA approval?
The genetic target of the protein drug Ceruletide Diethylamine is CCKAR. Ceruletide Diethylamine reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%ceruletide diethylamine%" OR LOWER(tradeNames_string) LIKE "%cerulet...
[{'UUID': 'DrugGeneTargets_v2_3461', 'drugName': 'Ceruletide Diethylamine', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'CCKAR (ENSG00000163394)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1963
Q59
What is the genetic target of the small molecule drug Netarsudil Dimesylate, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Netarsudil Dimesylate: ROCK2 and ROCK1. Netarsudil Dimesylate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%netarsudil dimesylate%" OR LOWER(tradeNames_string) LIKE "%netarsudi...
[{'UUID': 'DrugGeneTargets_v2_4693', 'drugName': 'Netarsudil Dimesylate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ROCK2 (ENSG00000134318), ROCK1 (ENSG00000067900)', 'yearOfFirstApproval': 2017, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.214
Q59
What is the genetic target of the small molecule drug Paricalcitol, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Paricalcitol is VDR. Paricalcitol reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%paricalcitol%" OR LOWER(tradeNames_string) LIKE "%paricalcitol%" OR ...
[{'UUID': 'DrugGeneTargets_v2_2779', 'drugName': 'Paricalcitol', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'VDR (ENSG00000111424)', 'yearOfFirstApproval': 1998, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.999
Q59
What is the genetic target of the small molecule drug Propiomazine, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Propiomazine is HRH1. Propiomazine reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%propiomazine%" OR LOWER(tradeNames_string) LIKE "%propiomazine%" OR ...
[{'UUID': 'DrugGeneTargets_v2_518', 'drugName': 'Propiomazine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 1960, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3422', 'drugName': 'Propiomazine Hydrochloride', 'dru...
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Q59.1269
Q59
What is the genetic target of the small molecule drug Iobenguane I 131, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Iobenguane I 131 is SLC6A2. Iobenguane I 131 reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%iobenguane i 131%" OR LOWER(tradeNames_string) LIKE "%iobenguane i 1...
[{'UUID': 'DrugGeneTargets_v2_5267', 'drugName': 'Iobenguane I 131', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A2 (ENSG00000103546)', 'yearOfFirstApproval': 2018, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.592
Q59
What is the genetic target of the small molecule drug Rosuvastatin Calcium, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Rosuvastatin Calcium is HMGCR. Rosuvastatin Calcium reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%rosuvastatin calcium%" OR LOWER(tradeNames_string) LIKE "%rosuvastat...
[{'UUID': 'DrugGeneTargets_v2_5208', 'drugName': 'Rosuvastatin Calcium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HMGCR (ENSG00000113161)', 'yearOfFirstApproval': 2003, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1391
Q59
What is the genetic target of the small molecule drug Trilaciclib Dihydrochloride, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Trilaciclib Dihydrochloride: CDK6 and CDK4. Trilaciclib Dihydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%trilaciclib dihydrochloride%" OR LOWER(tradeNames_string) LIKE "%tri...
[{'UUID': 'DrugGeneTargets_v2_3859', 'drugName': 'Trilaciclib Dihydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CDK6 (ENSG00000105810), CDK4 (ENSG00000135446)', 'yearOfFirstApproval': 2021, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_3860', 'drugN...
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Q59.1450
Q59
What is the genetic target of the small molecule drug Desoxycorticosterone Acetate, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Desoxycorticosterone Acetate is NR3C2. Desoxycorticosterone Acetate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%desoxycorticosterone acetate%" OR LOWER(tradeNames_string) LIKE "%de...
[{'UUID': 'DrugGeneTargets_v2_184', 'drugName': 'Desoxycorticosterone Acetate', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'NR3C2 (ENSG00000151623)', 'yearOfFirstApproval': 1939, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.279
Q59
What is the genetic target of the small molecule drug Nicardipine Hydrochloride, and what is its status in clinical trials and FDA approval?
There are 4 genetic targets of the small molecule drug Nicardipine Hydrochloride: CACNA1C, CACNA1S, CACNA1D, and CACNA1F. Nicardipine Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%nicardipine hydrochloride%" OR LOWER(tradeNames_string) LIKE "%nicar...
[{'UUID': 'DrugGeneTargets_v2_320', 'drugName': 'Nicardipine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CACNA1C (ENSG00000151067), CACNA1S (ENSG00000081248), CACNA1D (ENSG00000157388), CACNA1F (ENSG00000102001)', 'yearOfFirstApproval': 1988, 'maxClinicalTrialPhase': 4, 'drugIsApp...
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Q59.1507
Q59
What is the genetic target of the small molecule drug Promazine, and what is its status in clinical trials and FDA approval?
There are 4 genetic targets of the small molecule drug Promazine: DRD2, DRD3, DRD4, and HTR2A. Promazine reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%promazine%" OR LOWER(tradeNames_string) LIKE "%promazine%" OR LOWER(...
[{'UUID': 'DrugGeneTargets_v2_3300', 'drugName': 'Apomorphine Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DRD2 (ENSG00000149295), DRD3 (ENSG00000151577), DRD4 (ENSG00000069696)', 'yearOfFirstApproval': 2004, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTa...
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Q59.1328
Q59
What is the genetic target of the small molecule drug Trelagliptin, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Trelagliptin is DPP4. Trelagliptin reached phase 3 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%trelagliptin%" OR LOWER(tradeNames_string) LIKE "%trelagliptin%" OR ...
[{'UUID': 'DrugGeneTargets_v2_707', 'drugName': 'Trelagliptin', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'DPP4 (ENSG00000197635)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False}, {'UUID': 'DrugGeneTargets_v2_3478', 'drugName': 'Trelagliptin Succinate', 'drugMolec...
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Q59.1271
Q59
What is the genetic target of the small molecule drug Dextrothyroxine Sodium, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Dextrothyroxine Sodium: THRA and THRB. Dextrothyroxine Sodium reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%dextrothyroxine sodium%" OR LOWER(tradeNames_string) LIKE "%dextroth...
[{'UUID': 'DrugGeneTargets_v2_4368', 'drugName': 'Dextrothyroxine Sodium', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'THRA (ENSG00000126351), THRB (ENSG00000151090)', 'yearOfFirstApproval': 1967, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1820
Q59
What is the genetic target of the protein drug Pasireotide Pamoate, and what is its status in clinical trials and FDA approval?
There are 4 genetic targets of the protein drug Pasireotide Pamoate: SSTR3, SSTR5, SSTR2, and SSTR1. Pasireotide Pamoate reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%pasireotide pamoate%" OR LOWER(tradeNames_string) LIKE "%pasireotide...
[{'UUID': 'DrugGeneTargets_v2_6121', 'drugName': 'Pasireotide Pamoate', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'SSTR3 (ENSG00000278195), SSTR5 (ENSG00000162009), SSTR2 (ENSG00000180616), SSTR1 (ENSG00000139874)', 'yearOfFirstApproval': 2014, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUI...
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Q59.273
Q59
What is the genetic target of the protein drug Cenegermin, and what is its status in clinical trials and FDA approval?
There are 3 genetic targets of the protein drug Cenegermin: NTRK1, NTRK2, and NTRK3. Cenegermin reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%cenegermin%" OR LOWER(tradeNames_string) LIKE "%cenegermin%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_3786', 'drugName': 'Cenegermin', 'drugMolecularType': 'Protein', 'newLinkedTargets_string': 'NTRK1 (ENSG00000198400), NTRK2 (ENSG00000148053), NTRK3 (ENSG00000140538)', 'yearOfFirstApproval': 2018, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}]
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Q59.1863
Q59
What is the genetic target of the small molecule drug Entrectinib, and what is its status in clinical trials and FDA approval?
There are 5 genetic targets of the small molecule drug Entrectinib: ROS1, ALK, NTRK1, NTRK2, and NTRK3. Entrectinib reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%entrectinib%" OR LOWER(tradeNames_string) LIKE "%entrectinib%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_1203', 'drugName': 'Entrectinib', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ROS1 (ENSG00000047936), ALK (ENSG00000171094), NTRK1 (ENSG00000198400), NTRK2 (ENSG00000148053), NTRK3 (ENSG00000140538)', 'yearOfFirstApproval': 2019, 'maxClinicalTrialPhase': 4, 'drugIsAp...
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Q59.578
Q59
What is the genetic target of the small molecule drug Fentanyl, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Fentanyl is OPRM1. Fentanyl reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%fentanyl%" OR LOWER(tradeNames_string) LIKE "%fentanyl%" OR LOWER(dr...
[{'UUID': 'DrugGeneTargets_v2_3916', 'drugName': 'Fentanyl Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'OPRM1 (ENSG00000112038)', 'yearOfFirstApproval': 2006, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_733', 'drugName': 'Fentanyl Citrate', 'dr...
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Q59.638
Q59
What is the genetic target of the small molecule drug Cobiprostone, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Cobiprostone is CLCN2. Cobiprostone reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%cobiprostone%" OR LOWER(tradeNames_string) LIKE "%cobiprostone%" OR ...
[{'UUID': 'DrugGeneTargets_v2_581', 'drugName': 'Cobiprostone', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'CLCN2 (ENSG00000114859)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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Q59.713
Q59
What is the genetic target of the small molecule drug Dyphylline, and what is its status in clinical trials and FDA approval?
There are 5 genetic targets of the small molecule drug Dyphylline: PDE4A, PDE4D, PDE4B, PDE4C, and PDE3A. Dyphylline reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%dyphylline%" OR LOWER(tradeNames_string) LIKE "%dyphylline%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_2641', 'drugName': 'Dyphylline', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PDE4A (ENSG00000065989), PDE4D (ENSG00000113448), PDE4B (ENSG00000184588), PDE4C (ENSG00000105650), PDE3A (ENSG00000172572)', 'yearOfFirstApproval': 1951, 'maxClinicalTrialPhase': 4, 'drugIs...
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Q59.1529
Q59
What is the genetic target of the small molecule drug Oxprenolol Hydrochloride, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Oxprenolol Hydrochloride: ADRB1 and ADRB2. Oxprenolol Hydrochloride reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%oxprenolol hydrochloride%" OR LOWER(tradeNames_string) LIKE "%oxpren...
[{'UUID': 'DrugGeneTargets_v2_152', 'drugName': 'Oxprenolol Hydrochloride', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'ADRB1 (ENSG00000043591), ADRB2 (ENSG00000169252)', 'yearOfFirstApproval': 1983, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_153', 'drugName...
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Q59.627
Q59
What is the genetic target of the small molecule drug Conivaptan, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Conivaptan: AVPR2 and AVPR1A. Conivaptan reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%conivaptan%" OR LOWER(tradeNames_string) LIKE "%conivaptan%" OR LOWE...
[{'UUID': 'DrugGeneTargets_v2_2594', 'drugName': 'Conivaptan', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'AVPR2 (ENSG00000126895), AVPR1A (ENSG00000166148)', 'yearOfFirstApproval': 2005, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_2593', 'drugName': 'Conivap...
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Q59.1991
Q59
What is the genetic target of the small molecule drug Clomipramine, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Clomipramine is SLC6A4. Clomipramine reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%clomipramine%" OR LOWER(tradeNames_string) LIKE "%clomipramine%" OR ...
[{'UUID': 'DrugGeneTargets_v2_4905', 'drugName': 'Clomipramine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'SLC6A4 (ENSG00000108576)', 'yearOfFirstApproval': 1989, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1137', 'drugName': 'Clomipramine Hydrochloride', '...
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Q59.813
Q59
What is the genetic target of the small molecule drug Pheniramine, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Pheniramine is HRH1. Pheniramine reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%pheniramine%" OR LOWER(tradeNames_string) LIKE "%pheniramine%" OR LO...
[{'UUID': 'DrugGeneTargets_v2_3635', 'drugName': 'Dexchlorpheniramine', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'HRH1 (ENSG00000196639)', 'yearOfFirstApproval': 1981, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_1578', 'drugName': 'Pheniramine', 'drugMolecu...
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Q59.309
Q59
What is the genetic target of the small molecule drug Aminocaproic Acid, and what is its status in clinical trials and FDA approval?
There are 2 genetic targets of the small molecule drug Aminocaproic Acid: PLAT and PLG. Aminocaproic Acid reached phase 4 clinical trials meaning it has been approved by the FDA.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%aminocaproic acid%" OR LOWER(tradeNames_string) LIKE "%aminocaproic ...
[{'UUID': 'DrugGeneTargets_v2_5590', 'drugName': 'Aminocaproic Acid', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'PLAT (ENSG00000104368), PLG (ENSG00000122194)', 'yearOfFirstApproval': 1964, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True}, {'UUID': 'DrugGeneTargets_v2_5591', 'drugName': 'Amin...
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Q59.550
Q59
What is the genetic target of the small molecule drug Rodatristat Ethyl, and what is its status in clinical trials and FDA approval?
The genetic target of the small molecule drug Rodatristat Ethyl is TPH1. Rodatristat Ethyl reached phase 2 clinical trials but is not approved by the FDA for treatment of any disease.
SELECT DISTINCT UUID, drugName, drugMolecularType, newLinkedTargets_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) LIKE "%rodatristat ethyl%" OR LOWER(tradeNames_string) LIKE "%rodatristat e...
[{'UUID': 'DrugGeneTargets_v2_1600', 'drugName': 'Rodatristat Ethyl', 'drugMolecularType': 'Small molecule', 'newLinkedTargets_string': 'TPH1 (ENSG00000129167)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False}]
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