uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
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|---|---|---|---|---|---|---|---|---|
Q67.450 | Q67 | What is the top-associated SNP of the gene IRF6 in Whole Blood mQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene IRF6 in Whole Blood mQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "IRF6" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_754646', 'topRSID': 'rs2357229', 'Disease': 'ALS', 'Gene': 'IRF6', 'p_SMR_multi': 0.920065, 'p_HEIDI': 0.9427284, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_754640', 'topRSID... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.401 | Q67 | What is the top-associated SNP of the gene RP11-259G18.3 in Skeletal Muscle eQTL omic data for PD and is it functionally significant? | The top-associated SNP for RP11-259G18.3 in Skeletal Muscle eQTL omic data for PD is rs169201, which has a multi-SNP SMR p-value of 1.82e-14 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.3" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1370547', 'topRSID': 'rs169201', 'Disease': 'PD', 'Gene': 'RP11-259G18.3', 'p_SMR_multi': 1.818091e-14, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Li... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.179 | Q67 | What is the top-associated SNP of the gene C9orf72 in Nucleus Accumbens Basal Ganglia omic data for ALS and is it functionally significant? | The top-associated SNP for C9orf72 in Nucleus Accumbens Basal Ganglia omic data for ALS is rs3736321, which has a multi-SNP SMR p-value of 6.04e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "C9orf72" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%nucleus accumbens basal ganglia%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1719531', 'topRSID': 'rs3736321', 'Disease': 'ALS', 'Gene': 'C9orf72', 'p_SMR_multi': 6.035943e-11, 'p_HEIDI': 0.000972053, 'Omic_tissue': 'Nucleus Accumbens Basal', 'Omic_type': 'Nucleus Accumbens Basal Ganglia', 'func_sig': 'association meets significance threshold but shows s... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1051 | Q67 | What is the top-associated SNP of the gene AKAP13 in Whole Brain meta-analysis mQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene AKAP13 in Whole Brain meta-analysis mQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "AKAP13" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_202578', 'topRSID': 'rs338543', 'Disease': 'ALS', 'Gene': 'AKAP13', 'p_SMR_multi': 0.08109204, 'p_HEIDI': 0.3221757, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1737 | Q67 | What is the top-associated SNP of the gene CTB-171A8.1 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for CTB-171A8.1 in Whole Brain meta-analysis mQTL omic data for AD is rs10410915, which has a multi-SNP SMR p-value of 1.48e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CTB-171A8.1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_122446', 'topRSID': 'rs10410915', 'Disease': 'AD', 'Gene': 'CTB-171A8.1', 'p_SMR_multi': 3.296369e-08, 'p_HEIDI': 0.0001542126, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of l... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1609 | Q67 | What is the top-associated SNP of the gene TRIM31 in Whole Brain meta-analysis mQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene TRIM31 in Whole Brain meta-analysis mQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TRIM31" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_346843', 'topRSID': 'rs3132123', 'Disease': 'LBD', 'Gene': 'TRIM31', 'p_SMR_multi': 0.0922309, 'p_HEIDI': 0.6978468, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1869 | Q67 | What is the top-associated SNP of the gene PSMC3 in Caudate Basal Ganglia eQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene PSMC3 in Caudate Basal Ganglia eQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PSMC3" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%caudate basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1267307', 'topRSID': 'rs7101772', 'Disease': 'AD', 'Gene': 'PSMC3', 'p_SMR_multi': 0.006744941, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Caudate Basal Ganglia', 'Omic_type': 'Caudate Basal Ganglia eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.602 | Q67 | What is the top-associated SNP of the gene ARHGAP27 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PD and is it functionally significant? | The top-associated SNP for ARHGAP27 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PD is rs62065378, which has a multi-SNP SMR p-value of 4.98e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARHGAP27" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 1... | [{'UUID': 'NDD_SMR_genes_all_update_text_1435912', 'topRSID': 'rs62065378', 'Disease': 'PD', 'Gene': 'ARHGAP27', 'p_SMR_multi': 4.975346e-11, 'p_HEIDI': 0.002150515, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance thr... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.63 | Q67 | What is the top-associated SNP of the gene APOC2 in Cortex eQTL metaBrain omic data for AD and is it functionally significant? | The top-associated SNP for APOC2 in Cortex eQTL metaBrain omic data for AD is rs204474, which has a multi-SNP SMR p-value of 3.60e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "APOC2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1108031', 'topRSID': 'rs204474', 'Disease': 'AD', 'Gene': 'APOC2', 'p_SMR_multi': 3.59541e-08, 'p_HEIDI': 0.001231871, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequi... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1309 | Q67 | What is the top-associated SNP of the gene LRRC37A4P in Putamen Basal Ganglia eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for LRRC37A4P in Putamen Basal Ganglia eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 9.03e-18 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A4P" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%putamen basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1596818', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'LRRC37A4P', 'p_SMR_multi': 9.033016e-18, 'p_HEIDI': 1.1001010000000001e-18, 'Omic_tissue': 'Putamen Basal Ganglia', 'Omic_type': 'Putamen Basal Ganglia eQTL', 'func_sig': 'association meets significance threshold but s... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.879 | Q67 | What is the top-associated SNP of the gene PLEKHM1 in Frontal Cortex BA9 eQTL omic data for PD and is it functionally significant? | The top-associated SNP for PLEKHM1 in Frontal Cortex BA9 eQTL omic data for PD is rs79172804, which has a multi-SNP SMR p-value of 1.19e-06 and a HEIDI of 0.05, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PLEKHM1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%frontal cortex ba9 eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1168830', 'topRSID': 'rs79172804', 'Disease': 'PD', 'Gene': 'PLEKHM1', 'p_SMR_multi': 1.191544e-06, 'p_HEIDI': 0.05384652, 'Omic_tissue': 'Frontal Cortex', 'Omic_type': 'Frontal Cortex BA9 eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1491 | Q67 | What is the top-associated SNP of the gene IGSF9B in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for IGSF9B in Whole Blood mQTL omic data for PD is rs12574238, which has a multi-SNP SMR p-value of 6.26e-10 and a HEIDI of 0.01, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "IGSF9B" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_961101', 'topRSID': 'rs3802920', 'Disease': 'PD', 'Gene': 'IGSF9B', 'p_SMR_multi': 1.22563e-10, 'p_HEIDI': 0.0001625568, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1880 | Q67 | What is the top-associated SNP of the gene LRRC37A2 in Caudate Basal Ganglia eQTL omic data for PD and is it functionally significant? | The top-associated SNP for LRRC37A2 in Caudate Basal Ganglia eQTL omic data for PD is rs8073146, which has a multi-SNP SMR p-value of 6.34e-12 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A2" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%caudate basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1281362', 'topRSID': 'rs8073146', 'Disease': 'PD', 'Gene': 'LRRC37A2', 'p_SMR_multi': 6.342085e-12, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Caudate Basal Ganglia', 'Omic_type': 'Caudate Basal Ganglia eQTL', 'func_sig': 'association meets significance threshold but shows signs of lin... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.282 | Q67 | What is the top-associated SNP of the gene MLK4 in Nucleus Accumbens Basal Ganglia omic data for LBD and is it functionally significant? | There are no SNPs within the gene MLK4 in Nucleus Accumbens Basal Ganglia omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MLK4" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%nucleus accumbens basal ganglia%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1724642', 'topRSID': 'rs1402814', 'Disease': 'LBD', 'Gene': 'MLK4', 'p_SMR_multi': 0.1884045, 'p_HEIDI': 0.2238153, 'Omic_tissue': 'Nucleus Accumbens Basal', 'Omic_type': 'Nucleus Accumbens Basal Ganglia', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.37 | Q67 | What is the top-associated SNP of the gene ARHGAP27 in Whole Brain meta-analysis mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for ARHGAP27 in Whole Brain meta-analysis mQTL omic data for PSP is rs11012, which has a multi-SNP SMR p-value of 1.97e-15 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARHGAP27" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_560834', 'topRSID': 'rs11012', 'Disease': 'PSP', 'Gene': 'ARHGAP27', 'p_SMR_multi': 9.282341e-28, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Li... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1517 | Q67 | What is the top-associated SNP of the gene MAGI2 in Whole Blood mQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene MAGI2 in Whole Blood mQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAGI2" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_727551', 'topRSID': 'rs13239612', 'Disease': 'ALS', 'Gene': 'MAGI2', 'p_SMR_multi': 0.08157068, 'p_HEIDI': 0.1211621, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_727554', 'top... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.669 | Q67 | What is the top-associated SNP of the gene ARL17A in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PD and is it functionally significant? | The top-associated SNP for ARL17A in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PD is rs58879558, which has a multi-SNP SMR p-value of 3.03e-15 and a HEIDI of 0.16, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17A" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1435921', 'topRSID': 'rs58879558', 'Disease': 'PD', 'Gene': 'ARL17A', 'p_SMR_multi': 3.034114e-15, 'p_HEIDI': 0.1614406, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1829 | Q67 | What is the top-associated SNP of the gene SLC16A11 in Whole Blood mQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene SLC16A11 in Whole Blood mQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SLC16A11" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_670625', 'topRSID': 'rs188774', 'Disease': 'ALS', 'Gene': 'SLC16A11', 'p_SMR_multi': 0.7354693, 'p_HEIDI': 0.6519994, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_670624', 'top... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1446 | Q67 | What is the top-associated SNP of the gene CRHR1-IT1 in Tibial Nerve eQTL omic data for PD and is it functionally significant? | The top-associated SNP for CRHR1-IT1 in Tibial Nerve eQTL omic data for PD is rs4564621, which has a multi-SNP SMR p-value of 9.33e-15 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CRHR1-IT1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1328930', 'topRSID': 'rs4564621', 'Disease': 'PD', 'Gene': 'CRHR1-IT1', 'p_SMR_multi': 9.334656e-15, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.986 | Q67 | What is the top-associated SNP of the gene SEC13 in Whole Blood mQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene SEC13 in Whole Blood mQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SEC13" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_639402', 'topRSID': 'rs40608', 'Disease': 'AD', 'Gene': 'SEC13', 'p_SMR_multi': 0.1730001, 'p_HEIDI': 0.970879, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_639403', 'topRSID':... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1572 | Q67 | What is the top-associated SNP of the gene SLC26A1 in Cerebellum eQTL omic data for PD and is it functionally significant? | The top-associated SNP for SLC26A1 in Cerebellum eQTL omic data for PD is rs11936407, which has a multi-SNP SMR p-value of 5.28e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SLC26A1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1707343', 'topRSID': 'rs11936407', 'Disease': 'PD', 'Gene': 'SLC26A1', 'p_SMR_multi': 5.277755e-07, 'p_HEIDI': 1.417229e-05, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.745 | Q67 | What is the top-associated SNP of the gene RP11-66D17.5 in Cortex eQTL GTEx omic data for PD and is it functionally significant? | There are no SNPs within the gene RP11-66D17.5 in Cortex eQTL GTEx omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-66D17.5" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cortex eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1259372', 'topRSID': 'rs12143060', 'Disease': 'PD', 'Gene': 'RP11-66D17.5', 'p_SMR_multi': 0.9142541, 'p_HEIDI': 0.701279, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL GTEx', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.194 | Q67 | What is the top-associated SNP of the gene KANSL1 in Basal Ganglia eQTL omic data for PD and is it functionally significant? | The top-associated SNP for KANSL1 in Basal Ganglia eQTL omic data for PD is rs6503453, which has a multi-SNP SMR p-value of 2.35e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_27182', 'topRSID': 'rs6503453', 'Disease': 'PD', 'Gene': 'KANSL1', 'p_SMR_multi': 2.349001e-06, 'p_HEIDI': 0.0001370049, 'Omic_tissue': 'Basal Ganglia', 'Omic_type': 'Basal Ganglia eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage D... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.927 | Q67 | What is the top-associated SNP of the gene RP11-707O23.5 in Caudate Basal Ganglia eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-707O23.5 in Caudate Basal Ganglia eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 7.69e-16 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-707O23.5" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%caudate basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1283699', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'RP11-707O23.5', 'p_SMR_multi': 7.692125e-16, 'p_HEIDI': 6.582509000000001e-17, 'Omic_tissue': 'Caudate Basal Ganglia', 'Omic_type': 'Caudate Basal Ganglia eQTL', 'func_sig': 'association meets significance threshold bu... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.462 | Q67 | What is the top-associated SNP of the gene PM20D1 in Whole Brain meta-analysis mQTL omic data for PSP and is it functionally significant? | There are no SNPs within the gene PM20D1 in Whole Brain meta-analysis mQTL omic data that are significantly associated with PSP, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PM20D1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_510215', 'topRSID': 'rs11240574', 'Disease': 'PSP', 'Gene': 'PM20D1', 'p_SMR_multi': 0.2803787, 'p_HEIDI': 0.2263641, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.682 | Q67 | What is the top-associated SNP of the gene SCIMP in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for SCIMP in Whole Blood eQTL eQTLgen omic data for AD is rs4790253, which has a multi-SNP SMR p-value of 6.23e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SCIMP" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1501931', 'topRSID': 'rs4790253', 'Disease': 'AD', 'Gene': 'SCIMP', 'p_SMR_multi': 6.226141e-08, 'p_HEIDI': 4.131138e-11, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.767 | Q67 | What is the top-associated SNP of the gene CTB-171A8.1 in Cerebellum eQTL omic data for AD and is it functionally significant? | The top-associated SNP for CTB-171A8.1 in Cerebellum eQTL omic data for AD is rs79638902, which has a multi-SNP SMR p-value of 1.54e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CTB-171A8.1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1690529', 'topRSID': 'rs79638902', 'Disease': 'AD', 'Gene': 'CTB-171A8.1', 'p_SMR_multi': 1.540107e-08, 'p_HEIDI': 3.533378e-07, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1809 | Q67 | What is the top-associated SNP of the gene KANSL1-AS1 in Cerebellum eQTL omic data for PD and is it functionally significant? | The top-associated SNP for KANSL1-AS1 in Cerebellum eQTL omic data for PD is rs55974014, which has a multi-SNP SMR p-value of 2.32e-12 and a HEIDI of 0.73, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1-AS1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1710350', 'topRSID': 'rs55974014', 'Disease': 'PD', 'Gene': 'KANSL1-AS1', 'p_SMR_multi': 2.318566e-12, 'p_HEIDI': 0.7348483, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1603 | Q67 | What is the top-associated SNP of the gene ARHGAP27 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for ARHGAP27 in Whole Brain meta-analysis mQTL omic data for PD is rs62064641, which has a multi-SNP SMR p-value of 1.44e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARHGAP27" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491057', 'topRSID': 'rs62065376', 'Disease': 'PD', 'Gene': 'ARHGAP27', 'p_SMR_multi': 1.134698e-11, 'p_HEIDI': 0.3072466, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.735 | Q67 | What is the top-associated SNP of the gene CRHR1-IT1 in Tibial Nerve eQTL omic data for AD and is it functionally significant? | The top-associated SNP for CRHR1-IT1 in Tibial Nerve eQTL omic data for AD is rs4564621, which has a multi-SNP SMR p-value of 2.14e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CRHR1-IT1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1291757', 'topRSID': 'rs4564621', 'Disease': 'AD', 'Gene': 'CRHR1-IT1', 'p_SMR_multi': 2.139081e-06, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.418 | Q67 | What is the top-associated SNP of the gene AC012146.7 in Hypothalamus eQTL omic data for AD and is it functionally significant? | The top-associated SNP for AC012146.7 in Hypothalamus eQTL omic data for AD is rs56197642, which has a multi-SNP SMR p-value of 1.46e-06 and a HEIDI of 0.17, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "AC012146.7" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%hypothalamus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1454298', 'topRSID': 'rs56197642', 'Disease': 'AD', 'Gene': 'AC012146.7', 'p_SMR_multi': 1.461988e-06, 'p_HEIDI': 0.1651061, 'Omic_tissue': 'Hypothalamus', 'Omic_type': 'Hypothalamus eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1107 | Q67 | What is the top-associated SNP of the gene TRIM4 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for TRIM4 in Whole Blood eQTL eQTLgen omic data for AD is rs2571997, which has a multi-SNP SMR p-value of 5.47e-12 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TRIM4" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1495786', 'topRSID': 'rs2571997', 'Disease': 'AD', 'Gene': 'TRIM4', 'p_SMR_multi': 5.465386e-12, 'p_HEIDI': 2.154715e-05, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.832 | Q67 | What is the top-associated SNP of the gene LRRFIP2 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for LRRFIP2 in Whole Blood eQTL eQTLgen omic data for AD is rs17810211, which has a multi-SNP SMR p-value of 2.56e-06 and a HEIDI of 0.09, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRFIP2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1492564', 'topRSID': 'rs17810211', 'Disease': 'AD', 'Gene': 'LRRFIP2', 'p_SMR_multi': 2.560905e-06, 'p_HEIDI': 0.08822957, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1498 | Q67 | What is the top-associated SNP of the gene ERBB2 in Whole Brain meta-analysis mQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene ERBB2 in Whole Brain meta-analysis mQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ERBB2" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_395255', 'topRSID': 'rs2934967', 'Disease': 'LBD', 'Gene': 'ERBB2', 'p_SMR_multi': 0.2695209, 'p_HEIDI': 0.6195235, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_3... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.623 | Q67 | What is the top-associated SNP of the gene IDUA in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for IDUA in Whole Brain meta-analysis mQTL omic data for PD is rs1051613, which has a multi-SNP SMR p-value of 8.18e-11 and a HEIDI of 0.05, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "IDUA" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_429873', 'topRSID': 'rs1051613', 'Disease': 'PD', 'Gene': 'IDUA', 'p_SMR_multi': 4.554749e-13, 'p_HEIDI': 2.213052e-05, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.117 | Q67 | What is the top-associated SNP of the gene KLC3 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for KLC3 in Whole Blood eQTL eQTLgen omic data for AD is rs9749618, which has a multi-SNP SMR p-value of 2.48e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KLC3" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1503919', 'topRSID': 'rs9749618', 'Disease': 'AD', 'Gene': 'KLC3', 'p_SMR_multi': 2.478716e-06, 'p_HEIDI': 0.0002007979, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linka... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.423 | Q67 | What is the top-associated SNP of the gene IGSF9B in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for IGSF9B in Whole Brain meta-analysis mQTL omic data for PD is rs1793680, which has a multi-SNP SMR p-value of 2.07e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "IGSF9B" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_470339', 'topRSID': 'rs1793680', 'Disease': 'PD', 'Gene': 'IGSF9B', 'p_SMR_multi': 2.071103e-10, 'p_HEIDI': 0.006061729, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1911 | Q67 | What is the top-associated SNP of the gene FAM200B in Cortex eQTL metaBrain omic data for PD and is it functionally significant? | The top-associated SNP for FAM200B in Cortex eQTL metaBrain omic data for PD is rs28402170, which has a multi-SNP SMR p-value of 4.41e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "FAM200B" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1140327', 'topRSID': 'rs28402170', 'Disease': 'PD', 'Gene': 'FAM200B', 'p_SMR_multi': 4.407789e-07, 'p_HEIDI': 0.0001840489, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage D... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.978 | Q67 | What is the top-associated SNP of the gene ZNF726 in Tibial Nerve eQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene ZNF726 in Tibial Nerve eQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ZNF726" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1329595', 'topRSID': 'rs368730501', 'Disease': 'PD', 'Gene': 'ZNF726', 'p_SMR_multi': 0.3454371, 'p_HEIDI': 0.1425176, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.611 | Q67 | What is the top-associated SNP of the gene CHURC1 in Whole Blood eQTL eQTLgen omic data for PD and is it functionally significant? | There are no SNPs within the gene CHURC1 in Whole Blood eQTL eQTLgen omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CHURC1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1562578', 'topRSID': 'rs7143764', 'Disease': 'PD', 'Gene': 'CHURC1', 'p_SMR_multi': 0.725602, 'p_HEIDI': 0.165383, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1919 | Q67 | What is the top-associated SNP of the gene CTA-212D2.2 in Whole Brain meta-analysis mQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene CTA-212D2.2 in Whole Brain meta-analysis mQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CTA-212D2.2" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_350400', 'topRSID': 'rs11759062', 'Disease': 'LBD', 'Gene': 'CTA-212D2.2', 'p_SMR_multi': 0.4254166, 'p_HEIDI': 0.6976929, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.92 | Q67 | What is the top-associated SNP of the gene ARHGAP27 in Whole Brain meta-analysis mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for ARHGAP27 in Whole Brain meta-analysis mQTL omic data for PSP is rs11012, which has a multi-SNP SMR p-value of 1.79e-17 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARHGAP27" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_560834', 'topRSID': 'rs11012', 'Disease': 'PSP', 'Gene': 'ARHGAP27', 'p_SMR_multi': 9.282341e-28, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Li... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.855 | Q67 | What is the top-associated SNP of the gene APOC2 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for APOC2 in Whole Blood mQTL omic data for AD is rs5120, which has a multi-SNP SMR p-value of 1.44e-24 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "APOC2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_637437', 'topRSID': 'rs5120', 'Disease': 'AD', 'Gene': 'APOC2', 'p_SMR_multi': 1.276397e-24, 'p_HEIDI': 2.572368e-19, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequil... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1521 | Q67 | What is the top-associated SNP of the gene C6orf10 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for C6orf10 in Whole Blood mQTL omic data for AD is rs35265698, which has a multi-SNP SMR p-value of 5.71e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "C6orf10" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_621662', 'topRSID': 'rs35265698', 'Disease': 'AD', 'Gene': 'C6orf10', 'p_SMR_multi': 2.929935e-08, 'p_HEIDI': 2.344082e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Di... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1918 | Q67 | What is the top-associated SNP of the gene DGKQ in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for DGKQ in Whole Blood mQTL omic data for PD is rs3733346, which has a multi-SNP SMR p-value of 8.20e-08 and a HEIDI of 0.01, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DGKQ" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_996294', 'topRSID': 'rs2290402', 'Disease': 'PD', 'Gene': 'DGKQ', 'p_SMR_multi': 3.044298e-09, 'p_HEIDI': 1.349111e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.760 | Q67 | What is the top-associated SNP of the gene FBRSL1 in Whole Blood mQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene FBRSL1 in Whole Blood mQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "FBRSL1" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_790266', 'topRSID': 'rs77540893', 'Disease': 'FTD', 'Gene': 'FBRSL1', 'p_SMR_multi': 0.06649195, 'p_HEIDI': 0.7984426, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_790245', 'to... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.504 | Q67 | What is the top-associated SNP of the gene GPNMB in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for GPNMB in Whole Brain meta-analysis mQTL omic data for PD is rs199357, which has a multi-SNP SMR p-value of 1.39e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GPNMB" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_447897', 'topRSID': 'rs199357', 'Disease': 'PD', 'Gene': 'GPNMB', 'p_SMR_multi': 1.890519e-08, 'p_HEIDI': 0.02394197, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_447... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1287 | Q67 | What is the top-associated SNP of the gene RP11-196G11.2 in Tibial Nerve eQTL omic data for PD and is it functionally significant? | The top-associated SNP for RP11-196G11.2 in Tibial Nerve eQTL omic data for PD is rs732172, which has a multi-SNP SMR p-value of 9.65e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-196G11.2" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1328407', 'topRSID': 'rs732172', 'Disease': 'PD', 'Gene': 'RP11-196G11.2', 'p_SMR_multi': 9.652395e-08, 'p_HEIDI': 0.00161836, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linka... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1340 | Q67 | What is the top-associated SNP of the gene DND1P1 in Cerebellum eQTL omic data for PD and is it functionally significant? | The top-associated SNP for DND1P1 in Cerebellum eQTL omic data for PD is rs55974014, which has a multi-SNP SMR p-value of 9.30e-10 and a HEIDI of 0.72, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DND1P1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1710345', 'topRSID': 'rs55974014', 'Disease': 'PD', 'Gene': 'DND1P1', 'p_SMR_multi': 9.299729e-10, 'p_HEIDI': 0.7217328, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.12 | Q67 | What is the top-associated SNP of the gene ARL17A in Spinalcord eQTL omic data for PD and is it functionally significant? | The top-associated SNP for ARL17A in Spinalcord eQTL omic data for PD is rs6503453, which has a multi-SNP SMR p-value of 1.07e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17A" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%spinalcord eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_30032', 'topRSID': 'rs6503453', 'Disease': 'PD', 'Gene': 'ARL17A', 'p_SMR_multi': 1.073847e-06, 'p_HEIDI': 4.66739e-05, 'Omic_tissue': 'Spinalcord', 'Omic_type': 'Spinalcord eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequil... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.402 | Q67 | What is the top-associated SNP of the gene ALPL in Whole Blood mQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene ALPL in Whole Blood mQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ALPL" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_650727', 'topRSID': 'rs3753782', 'Disease': 'AD', 'Gene': 'ALPL', 'p_SMR_multi': 0.1186699, 'p_HEIDI': 0.9845278, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_650724', 'topRSID... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.288 | Q67 | What is the top-associated SNP of the gene RP11-960L18.1 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for RP11-960L18.1 in Whole Blood eQTL eQTLgen omic data for AD is rs12446759, which has a multi-SNP SMR p-value of 3.27e-08 and a HEIDI of 0.08, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-960L18.1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1501732', 'topRSID': 'rs12446759', 'Disease': 'AD', 'Gene': 'RP11-960L18.1', 'p_SMR_multi': 3.273907e-08, 'p_HEIDI': 0.08043591, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1075 | Q67 | What is the top-associated SNP of the gene ZNF296 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD and is it functionally significant? | The top-associated SNP for ZNF296 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD is rs8100183, which has a multi-SNP SMR p-value of 4.95e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ZNF296" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1397649', 'topRSID': 'rs8100183', 'Disease': 'AD', 'Gene': 'ZNF296', 'p_SMR_multi': 4.947535e-09, 'p_HEIDI': 5.789577e-09, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance thres... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1201 | Q67 | What is the top-associated SNP of the gene NAAA in Whole Blood eQTL eQTLgen omic data for PD and is it functionally significant? | The top-associated SNP for NAAA in Whole Blood eQTL eQTLgen omic data for PD is rs11732759, which has a multi-SNP SMR p-value of 3.53e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NAAA" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1555885', 'topRSID': 'rs11732759', 'Disease': 'PD', 'Gene': 'NAAA', 'p_SMR_multi': 3.5262e-07, 'p_HEIDI': 0.003914818, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1746 | Q67 | What is the top-associated SNP of the gene FAXC in Whole Brain meta-analysis mQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene FAXC in Whole Brain meta-analysis mQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "FAXC" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_163649', 'topRSID': 'rs9376100', 'Disease': 'ALS', 'Gene': 'FAXC', 'p_SMR_multi': 0.2987267, 'p_HEIDI': 0.9057299, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_16... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.697 | Q67 | What is the top-associated SNP of the gene KANSL1-AS1 in Amygdala eQTL omic data for PD and is it functionally significant? | The top-associated SNP for KANSL1-AS1 in Amygdala eQTL omic data for PD is rs9896243, which has a multi-SNP SMR p-value of 2.28e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1-AS1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%amygdala eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1603776', 'topRSID': 'rs9896243', 'Disease': 'PD', 'Gene': 'KANSL1-AS1', 'p_SMR_multi': 2.280565e-10, 'p_HEIDI': 0.002036426, 'Omic_tissue': 'Amygdala', 'Omic_type': 'Amygdala eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1632 | Q67 | What is the top-associated SNP of the gene RP11-259G18.3 in Skeletal Muscle eQTL omic data for AD and is it functionally significant? | The top-associated SNP for RP11-259G18.3 in Skeletal Muscle eQTL omic data for AD is rs169201, which has a multi-SNP SMR p-value of 8.43e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.3" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1343156', 'topRSID': 'rs169201', 'Disease': 'AD', 'Gene': 'RP11-259G18.3', 'p_SMR_multi': 8.431199e-07, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Li... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1877 | Q67 | What is the top-associated SNP of the gene PVR in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD and is it functionally significant? | The top-associated SNP for PVR in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD is rs11540084, which has a multi-SNP SMR p-value of 7.95e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PVR" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1397643', 'topRSID': 'rs11540084', 'Disease': 'AD', 'Gene': 'PVR', 'p_SMR_multi': 7.947475e-10, 'p_HEIDI': 3.133981e-11, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance thresho... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.696 | Q67 | What is the top-associated SNP of the gene CEACAM19 in Cortex eQTL metaBrain omic data for AD and is it functionally significant? | The top-associated SNP for CEACAM19 in Cortex eQTL metaBrain omic data for AD is rs714948, which has a multi-SNP SMR p-value of 6.32e-13 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CEACAM19" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1108029', 'topRSID': 'rs714948', 'Disease': 'AD', 'Gene': 'CEACAM19', 'p_SMR_multi': 6.324417e-13, 'p_HEIDI': 4.276112e-06, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Di... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.858 | Q67 | What is the top-associated SNP of the gene BIN1 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for BIN1 in Whole Blood mQTL omic data for AD is rs10194375, which has a multi-SNP SMR p-value of 8.38e-17 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "BIN1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_631119', 'topRSID': 'rs58402148', 'Disease': 'AD', 'Gene': 'BIN1', 'p_SMR_multi': 2.405281e-31, 'p_HEIDI': 3.999879e-37, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.162 | Q67 | What is the top-associated SNP of the gene RP11-707O23.5 in Prefrontal Cortex eQTL omic data for AD and is it functionally significant? | The top-associated SNP for RP11-707O23.5 in Prefrontal Cortex eQTL omic data for AD is rs2732705, which has a multi-SNP SMR p-value of 8.70e-07 and a HEIDI of 0.02, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-707O23.5" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%prefrontal cortex eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1203002', 'topRSID': 'rs2732705', 'Disease': 'AD', 'Gene': 'RP11-707O23.5', 'p_SMR_multi': 8.695728e-07, 'p_HEIDI': 0.02284462, 'Omic_tissue': 'Prefrontal Cortex', 'Omic_type': 'Prefrontal Cortex eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.902 | Q67 | What is the top-associated SNP of the gene FAM57B in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for FAM57B in Whole Blood mQTL omic data for AD is rs11642399, which has a multi-SNP SMR p-value of 2.64e-08 and a HEIDI of 0.07, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "FAM57B" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_577429', 'topRSID': 'rs11642399', 'Disease': 'AD', 'Gene': 'FAM57B', 'p_SMR_multi': 2.638529e-08, 'p_HEIDI': 0.06960655, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_577433', 'topR... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1576 | Q67 | What is the top-associated SNP of the gene ARL17A in Prefrontal Cortex eQTL omic data for AD and is it functionally significant? | The top-associated SNP for ARL17A in Prefrontal Cortex eQTL omic data for AD is rs2696466, which has a multi-SNP SMR p-value of 9.79e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17A" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%prefrontal cortex eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1203023', 'topRSID': 'rs2696466', 'Disease': 'AD', 'Gene': 'ARL17A', 'p_SMR_multi': 9.787664e-07, 'p_HEIDI': 0.002600192, 'Omic_tissue': 'Prefrontal Cortex', 'Omic_type': 'Prefrontal Cortex eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.260 | Q67 | What is the top-associated SNP of the gene DND1P1 in Anterior Cingulate Cortex BA24 eQTL omic data for PD and is it functionally significant? | The top-associated SNP for DND1P1 in Anterior Cingulate Cortex BA24 eQTL omic data for PD is rs55974014, which has a multi-SNP SMR p-value of 5.50e-10 and a HEIDI of 0.52, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DND1P1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%anterior cingulate cortex ba24 eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1488136', 'topRSID': 'rs55974014', 'Disease': 'PD', 'Gene': 'DND1P1', 'p_SMR_multi': 5.499578e-10, 'p_HEIDI': 0.5188977, 'Omic_tissue': 'Anterior Cingulate Cortex BA24', 'Omic_type': 'Anterior Cingulate Cortex BA24 eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.339 | Q67 | What is the top-associated SNP of the gene KANSL1 in Tibial Nerve eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for KANSL1 in Tibial Nerve eQTL omic data for PSP is rs6503455, which has a multi-SNP SMR p-value of 4.86e-15 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1336290', 'topRSID': 'rs6503455', 'Disease': 'PSP', 'Gene': 'KANSL1', 'p_SMR_multi': 4.855658e-15, 'p_HEIDI': 6.404704e-16, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1881 | Q67 | What is the top-associated SNP of the gene CNN2 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for CNN2 in Whole Blood mQTL omic data for AD is rs7247087, which has a multi-SNP SMR p-value of 1.30e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CNN2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_634277', 'topRSID': 'rs7247087', 'Disease': 'AD', 'Gene': 'CNN2', 'p_SMR_multi': 1.304171e-10, 'p_HEIDI': 9.291437e-15, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1048 | Q67 | What is the top-associated SNP of the gene FAM215B in Cerebellum eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for FAM215B in Cerebellum eQTL omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 6.81e-16 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "FAM215B" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1714165', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'FAM215B', 'p_SMR_multi': 6.809593e-16, 'p_HEIDI': 4.602325e-07, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dise... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.521 | Q67 | What is the top-associated SNP of the gene RPS26P8 in Prefrontal Cortex eQTL omic data for AD and is it functionally significant? | The top-associated SNP for RPS26P8 in Prefrontal Cortex eQTL omic data for AD is rs2732705, which has a multi-SNP SMR p-value of 1.84e-06 and a HEIDI of 0.05, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RPS26P8" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%prefrontal cortex eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1203003', 'topRSID': 'rs2732705', 'Disease': 'AD', 'Gene': 'RPS26P8', 'p_SMR_multi': 1.839777e-06, 'p_HEIDI': 0.04783226, 'Omic_tissue': 'Prefrontal Cortex', 'Omic_type': 'Prefrontal Cortex eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1363 | Q67 | What is the top-associated SNP of the gene HSD3B7 in Prefrontal Cortex eQTL omic data for PD and is it functionally significant? | The top-associated SNP for HSD3B7 in Prefrontal Cortex eQTL omic data for PD is rs13708, which has a multi-SNP SMR p-value of 7.64e-07 and a HEIDI of 0.09, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "HSD3B7" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%prefrontal cortex eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1241724', 'topRSID': 'rs13708', 'Disease': 'PD', 'Gene': 'HSD3B7', 'p_SMR_multi': 7.637274e-07, 'p_HEIDI': 0.09362997, 'Omic_tissue': 'Prefrontal Cortex', 'Omic_type': 'Prefrontal Cortex eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1024 | Q67 | What is the top-associated SNP of the gene EPHX2 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for EPHX2 in Whole Brain meta-analysis mQTL omic data for AD is rs10096092, which has a multi-SNP SMR p-value of 3.23e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "EPHX2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_78248', 'topRSID': 'rs73227337', 'Disease': 'AD', 'Gene': 'EPHX2', 'p_SMR_multi': 1.500668e-09, 'p_HEIDI': 0.01595741, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_78... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.775 | Q67 | What is the top-associated SNP of the gene PVRL2 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for PVRL2 in Whole Blood eQTL eQTLgen omic data for AD is rs17561351, which has a multi-SNP SMR p-value of 2.64e-80 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PVRL2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1503906', 'topRSID': 'rs17561351', 'Disease': 'AD', 'Gene': 'PVRL2', 'p_SMR_multi': 2.635403e-80, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1748 | Q67 | What is the top-associated SNP of the gene MAPT-AS1 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for MAPT-AS1 in Whole Blood mQTL omic data for AD is rs10445363, which has a multi-SNP SMR p-value of 1.02e-06 and a HEIDI of 0.06, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT-AS1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_591182', 'topRSID': 'rs112310745', 'Disease': 'AD', 'Gene': 'MAPT-AS1', 'p_SMR_multi': 7.625542e-07, 'p_HEIDI': 0.02525318, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_591183', 't... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.768 | Q67 | What is the top-associated SNP of the gene MMRN1 in Frontal Cortex BA9 eQTL omic data for PD and is it functionally significant? | The top-associated SNP for MMRN1 in Frontal Cortex BA9 eQTL omic data for PD is rs75943295, which has a multi-SNP SMR p-value of 3.95e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MMRN1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%frontal cortex ba9 eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1167152', 'topRSID': 'rs75943295', 'Disease': 'PD', 'Gene': 'MMRN1', 'p_SMR_multi': 3.950646e-08, 'p_HEIDI': 0.002681861, 'Omic_tissue': 'Frontal Cortex', 'Omic_type': 'Frontal Cortex BA9 eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Li... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1256 | Q67 | What is the top-associated SNP of the gene KANSL1 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for KANSL1 in Whole Brain meta-analysis mQTL omic data for PD is rs571792649, which has a multi-SNP SMR p-value of 1.08e-13 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491139', 'topRSID': 'rs12150087', 'Disease': 'PD', 'Gene': 'KANSL1', 'p_SMR_multi': 8.107128999999999e-20, 'p_HEIDI': 0.009069932, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs o... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1213 | Q67 | What is the top-associated SNP of the gene RP11-259G18.1 in Anterior Cingulate Cortex BA24 eQTL omic data for PD and is it functionally significant? | The top-associated SNP for RP11-259G18.1 in Anterior Cingulate Cortex BA24 eQTL omic data for PD is rs199531, which has a multi-SNP SMR p-value of 6.66e-09 and a HEIDI of 0.12, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%anterior cingulate cortex ba24 eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1488143', 'topRSID': 'rs199531', 'Disease': 'PD', 'Gene': 'RP11-259G18.1', 'p_SMR_multi': 6.65777e-09, 'p_HEIDI': 0.1234044, 'Omic_tissue': 'Anterior Cingulate Cortex BA24', 'Omic_type': 'Anterior Cingulate Cortex BA24 eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1469 | Q67 | What is the top-associated SNP of the gene PVR in Prefrontal Cortex eQTL omic data for AD and is it functionally significant? | The top-associated SNP for PVR in Prefrontal Cortex eQTL omic data for AD is rs2301275, which has a multi-SNP SMR p-value of 1.60e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PVR" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%prefrontal cortex eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1203795', 'topRSID': 'rs2301275', 'Disease': 'AD', 'Gene': 'PVR', 'p_SMR_multi': 1.598998e-11, 'p_HEIDI': 1.923418e-06, 'Omic_tissue': 'Prefrontal Cortex', 'Omic_type': 'Prefrontal Cortex eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Li... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1984 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for MAPT in Whole Blood mQTL omic data for PD is rs112155389, which has a multi-SNP SMR p-value of 3.70e-14 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_948891', 'topRSID': 'rs62063271', 'Disease': 'PD', 'Gene': 'MAPT', 'p_SMR_multi': 6.382411e-15, 'p_HEIDI': 2.368028e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.527 | Q67 | What is the top-associated SNP of the gene NHLH1 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene NHLH1 in Whole Brain meta-analysis mQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NHLH1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_415797', 'topRSID': 'rs1249557', 'Disease': 'PD', 'Gene': 'NHLH1', 'p_SMR_multi': 0.1597603, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_4157... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.23 | Q67 | What is the top-associated SNP of the gene KANSL1 in Prefrontal Cortex eQTL omic data for AD and is it functionally significant? | The top-associated SNP for KANSL1 in Prefrontal Cortex eQTL omic data for AD is rs199447, which has a multi-SNP SMR p-value of 7.67e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%prefrontal cortex eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1203011', 'topRSID': 'rs199447', 'Disease': 'AD', 'Gene': 'KANSL1', 'p_SMR_multi': 7.667099e-08, 'p_HEIDI': 0.0002523026, 'Omic_tissue': 'Prefrontal Cortex', 'Omic_type': 'Prefrontal Cortex eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.361 | Q67 | What is the top-associated SNP of the gene CRHR1-IT1 in Skeletal Muscle eQTL omic data for AD and is it functionally significant? | The top-associated SNP for CRHR1-IT1 in Skeletal Muscle eQTL omic data for AD is rs62055888, which has a multi-SNP SMR p-value of 1.99e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CRHR1-IT1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1343151', 'topRSID': 'rs62055888', 'Disease': 'AD', 'Gene': 'CRHR1-IT1', 'p_SMR_multi': 1.988466e-06, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1288 | Q67 | What is the top-associated SNP of the gene ASIC4 in Tibial Nerve eQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene ASIC4 in Tibial Nerve eQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ASIC4" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1294950', 'topRSID': 'rs907676', 'Disease': 'ALS', 'Gene': 'ASIC4', 'p_SMR_multi': 0.3164977, 'p_HEIDI': 0.7420618, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1326 | Q67 | What is the top-associated SNP of the gene DGKQ in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for DGKQ in Whole Blood mQTL omic data for PD is rs13101828, which has a multi-SNP SMR p-value of 2.74e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DGKQ" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_996294', 'topRSID': 'rs2290402', 'Disease': 'PD', 'Gene': 'DGKQ', 'p_SMR_multi': 3.044298e-09, 'p_HEIDI': 1.349111e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1683 | Q67 | What is the top-associated SNP of the gene RP11-259G18.2 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for RP11-259G18.2 in Whole Brain meta-analysis mQTL omic data for PD is rs578109777, which has a multi-SNP SMR p-value of 5.45e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.2" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491154', 'topRSID': 'rs578109777', 'Disease': 'PD', 'Gene': 'RP11-259G18.2', 'p_SMR_multi': 5.445399e-09, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of lin... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.344 | Q67 | What is the top-associated SNP of the gene LOC149620 in Whole Blood mQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene LOC149620 in Whole Blood mQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LOC149620" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_752344', 'topRSID': 'rs2477581', 'Disease': 'ALS', 'Gene': 'LOC149620', 'p_SMR_multi': 0.9075362, 'p_HEIDI': 0.9576694, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_752345', 't... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.437 | Q67 | What is the top-associated SNP of the gene MMRN1 in Caudate Basal Ganglia eQTL omic data for PD and is it functionally significant? | The top-associated SNP for MMRN1 in Caudate Basal Ganglia eQTL omic data for PD is rs75943295, which has a multi-SNP SMR p-value of 1.20e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MMRN1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%caudate basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1279470', 'topRSID': 'rs75943295', 'Disease': 'PD', 'Gene': 'MMRN1', 'p_SMR_multi': 1.204344e-06, 'p_HEIDI': 0.001264632, 'Omic_tissue': 'Caudate Basal Ganglia', 'Omic_type': 'Caudate Basal Ganglia eQTL', 'func_sig': 'association meets significance threshold but shows signs of l... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.479 | Q67 | What is the top-associated SNP of the gene MAPT-AS1 in Whole Blood mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for MAPT-AS1 in Whole Blood mQTL omic data for PSP is rs415430, which has a multi-SNP SMR p-value of 1.17e-28 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT-AS1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1041727', 'topRSID': 'rs415430', 'Disease': 'PSP', 'Gene': 'MAPT-AS1', 'p_SMR_multi': 1.165767e-28, 'p_HEIDI': 2.375653e-07, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage D... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.220 | Q67 | What is the top-associated SNP of the gene MMRN1 in Nucleus Accumbens Basal Ganglia omic data for PD and is it functionally significant? | The top-associated SNP for MMRN1 in Nucleus Accumbens Basal Ganglia omic data for PD is rs75943295, which has a multi-SNP SMR p-value of 8.38e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MMRN1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%nucleus accumbens basal ganglia%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1728267', 'topRSID': 'rs75943295', 'Disease': 'PD', 'Gene': 'MMRN1', 'p_SMR_multi': 8.379918e-07, 'p_HEIDI': 0.0009058691, 'Omic_tissue': 'Nucleus Accumbens Basal', 'Omic_type': 'Nucleus Accumbens Basal Ganglia', 'func_sig': 'association meets significance threshold but shows si... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.919 | Q67 | What is the top-associated SNP of the gene LRRC37A2 in Nucleus Accumbens Basal Ganglia omic data for PSP and is it functionally significant? | The top-associated SNP for LRRC37A2 in Nucleus Accumbens Basal Ganglia omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 8.01e-20 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A2" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%nucleus accumbens basal ganglia%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1732402', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'LRRC37A2', 'p_SMR_multi': 8.013994e-20, 'p_HEIDI': 4.028984e-24, 'Omic_tissue': 'Nucleus Accumbens Basal', 'Omic_type': 'Nucleus Accumbens Basal Ganglia', 'func_sig': 'association meets significance threshold but shows... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1237 | Q67 | What is the top-associated SNP of the gene KANSL1-AS1 in Nucleus Accumbens Basal Ganglia omic data for PSP and is it functionally significant? | The top-associated SNP for KANSL1-AS1 in Nucleus Accumbens Basal Ganglia omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 4.98e-21 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1-AS1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%nucleus accumbens basal ganglia%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1732395', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'KANSL1-AS1', 'p_SMR_multi': 4.976284e-21, 'p_HEIDI': 4.344131e-13, 'Omic_tissue': 'Nucleus Accumbens Basal', 'Omic_type': 'Nucleus Accumbens Basal Ganglia', 'func_sig': 'association meets significance threshold but show... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1597 | Q67 | What is the top-associated SNP of the gene ARL17B in Putamen Basal Ganglia eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for ARL17B in Putamen Basal Ganglia eQTL omic data for PSP is rs4792831, which has a multi-SNP SMR p-value of 5.64e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17B" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%putamen basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1596826', 'topRSID': 'rs4792831', 'Disease': 'PSP', 'Gene': 'ARL17B', 'p_SMR_multi': 5.641074e-07, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Putamen Basal Ganglia', 'Omic_type': 'Putamen Basal Ganglia eQTL', 'func_sig': 'association meets significance threshold but shows signs of link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1020 | Q67 | What is the top-associated SNP of the gene LRRC37A in Cerebellum eQTL omic data for PD and is it functionally significant? | The top-associated SNP for LRRC37A in Cerebellum eQTL omic data for PD is rs4510068, which has a multi-SNP SMR p-value of 1.71e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_19648', 'topRSID': 'rs4510068', 'Disease': 'PD', 'Gene': 'LRRC37A', 'p_SMR_multi': 1.713765e-11, 'p_HEIDI': 3.270415e-07, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1950 | Q67 | What is the top-associated SNP of the gene CELF1 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for CELF1 in Whole Blood mQTL omic data for AD is rs11039409, which has a multi-SNP SMR p-value of 2.66e-06 and a HEIDI of 0.41, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CELF1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_608497', 'topRSID': 'rs11039409', 'Disease': 'AD', 'Gene': 'CELF1', 'p_SMR_multi': 1.22676e-06, 'p_HEIDI': 0.3753996, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_608498', 'topRSID... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.96 | Q67 | What is the top-associated SNP of the gene STH in Cortex eQTL metaBrain omic data for PSP and is it functionally significant? | The top-associated SNP for STH in Cortex eQTL metaBrain omic data for PSP is rs393152, which has a multi-SNP SMR p-value of 5.09e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "STH" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1154396', 'topRSID': 'rs393152', 'Disease': 'PSP', 'Gene': 'STH', 'p_SMR_multi': 5.090521e-09, 'p_HEIDI': 2.777608e-05, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1017 | Q67 | What is the top-associated SNP of the gene CEACAM19 in Cerebellum eQTL omic data for AD and is it functionally significant? | The top-associated SNP for CEACAM19 in Cerebellum eQTL omic data for AD is rs714948, which has a multi-SNP SMR p-value of 9.51e-09 and a HEIDI of 0.13, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CEACAM19" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1690531', 'topRSID': 'rs714948', 'Disease': 'AD', 'Gene': 'CEACAM19', 'p_SMR_multi': 9.50635e-09, 'p_HEIDI': 0.1329184, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_4008', 'topRSID':... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1079 | Q67 | What is the top-associated SNP of the gene DND1P1 in Amygdala eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for DND1P1 in Amygdala eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 3.50e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DND1P1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%amygdala eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1604710', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'DND1P1', 'p_SMR_multi': 3.495275e-11, 'p_HEIDI': 7.643693e-09, 'Omic_tissue': 'Amygdala', 'Omic_type': 'Amygdala eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequil... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1101 | Q67 | What is the top-associated SNP of the gene APOC1P1 in Whole Brain meta-analysis mQTL omic data for LBD and is it functionally significant? | The top-associated SNP for APOC1P1 in Whole Brain meta-analysis mQTL omic data for LBD is rs157595, which has a multi-SNP SMR p-value of 4.02e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "APOC1P1" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_402976', 'topRSID': 'rs157595', 'Disease': 'LBD', 'Gene': 'APOC1P1', 'p_SMR_multi': 4.017664e-07, 'p_HEIDI': 1.573378e-06, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1586 | Q67 | What is the top-associated SNP of the gene STAG3 in Hypothalamus eQTL omic data for AD and is it functionally significant? | The top-associated SNP for STAG3 in Hypothalamus eQTL omic data for AD is rs866500, which has a multi-SNP SMR p-value of 6.66e-07 and a HEIDI of 0.49, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "STAG3" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%hypothalamus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1453489', 'topRSID': 'rs866500', 'Disease': 'AD', 'Gene': 'STAG3', 'p_SMR_multi': 6.65674e-07, 'p_HEIDI': 0.4913814, 'Omic_tissue': 'Hypothalamus', 'Omic_type': 'Hypothalamus eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1321 | Q67 | What is the top-associated SNP of the gene ABL1 in Whole Blood eQTL eQTLgen omic data for PD and is it functionally significant? | There are no SNPs within the gene ABL1 in Whole Blood eQTL eQTLgen omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ABL1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1559506', 'topRSID': 'rs35993820', 'Disease': 'PD', 'Gene': 'ABL1', 'p_SMR_multi': 0.1515666, 'p_HEIDI': 0.4780447, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.703 | Q67 | What is the top-associated SNP of the gene RP11-798G7.6 in Whole Blood eQTL eQTLgen omic data for PD and is it functionally significant? | The top-associated SNP for RP11-798G7.6 in Whole Blood eQTL eQTLgen omic data for PD is rs113564729, which has a multi-SNP SMR p-value of 1.94e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-798G7.6" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1564779', 'topRSID': 'rs113564729', 'Disease': 'PD', 'Gene': 'RP11-798G7.6', 'p_SMR_multi': 1.944697e-11, 'p_HEIDI': 2.183737e-09, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1794 | Q67 | What is the top-associated SNP of the gene ST8SIA2 in Whole Brain meta-analysis mQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene ST8SIA2 in Whole Brain meta-analysis mQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ST8SIA2" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_295184', 'topRSID': 'rs7183703', 'Disease': 'FTD', 'Gene': 'ST8SIA2', 'p_SMR_multi': 0.230488, 'p_HEIDI': 0.5866076, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
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