uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
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|---|---|---|---|---|---|---|---|---|
Q67.1526 | Q67 | What is the top-associated SNP of the gene ANKFY1 in Whole Brain meta-analysis mQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene ANKFY1 in Whole Brain meta-analysis mQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ANKFY1" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_393665', 'topRSID': 'rs8078296', 'Disease': 'LBD', 'Gene': 'ANKFY1', 'p_SMR_multi': 0.2638816, 'p_HEIDI': 0.1780389, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1488 | Q67 | What is the top-associated SNP of the gene CEACAM19 in Amygdala eQTL omic data for AD and is it functionally significant? | The top-associated SNP for CEACAM19 in Amygdala eQTL omic data for AD is rs714948, which has a multi-SNP SMR p-value of 1.90e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CEACAM19" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%amygdala eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1598392', 'topRSID': 'rs714948', 'Disease': 'AD', 'Gene': 'CEACAM19', 'p_SMR_multi': 1.898209e-06, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Amygdala', 'Omic_type': 'Amygdala eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequilibriu... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1525 | Q67 | What is the top-associated SNP of the gene LRRC37A2 in Caudate Basal Ganglia eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for LRRC37A2 in Caudate Basal Ganglia eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 1.27e-19 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A2" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%caudate basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1283710', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'LRRC37A2', 'p_SMR_multi': 1.265662e-19, 'p_HEIDI': 7.341628000000002e-22, 'Omic_tissue': 'Caudate Basal Ganglia', 'Omic_type': 'Caudate Basal Ganglia eQTL', 'func_sig': 'association meets significance threshold but sho... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1492 | Q67 | What is the top-associated SNP of the gene DOC2A in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for DOC2A in Whole Blood mQTL omic data for AD is rs7191849, which has a multi-SNP SMR p-value of 4.54e-07 and a HEIDI of 0.35, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DOC2A" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_577418', 'topRSID': 'rs12921753', 'Disease': 'AD', 'Gene': 'DOC2A', 'p_SMR_multi': 5.575261e-12, 'p_HEIDI': 0.3441697, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_577427', 'topRSI... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1694 | Q67 | What is the top-associated SNP of the gene PVRL2 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for PVRL2 in Whole Blood mQTL omic data for AD is rs149529419, which has a multi-SNP SMR p-value of 5.51e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PVRL2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_637426', 'topRSID': 'rs149529419', 'Disease': 'AD', 'Gene': 'PVRL2', 'p_SMR_multi': 5.514291e-09, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequil... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1716 | Q67 | What is the top-associated SNP of the gene RP11-259G18.3 in Cerebellar Hemisphere eQTL omic data for PD and is it functionally significant? | The top-associated SNP for RP11-259G18.3 in Cerebellar Hemisphere eQTL omic data for PD is rs55974014, which has a multi-SNP SMR p-value of 6.75e-12 and a HEIDI of 0.16, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.3" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cerebellar hemisphere eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1191174', 'topRSID': 'rs55974014', 'Disease': 'PD', 'Gene': 'RP11-259G18.3', 'p_SMR_multi': 6.749073e-12, 'p_HEIDI': 0.1644817, 'Omic_tissue': 'Cerebellar Hemisphere', 'Omic_type': 'Cerebellar Hemisphere eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1246 | Q67 | What is the top-associated SNP of the gene SPAG7 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for SPAG7 in Whole Blood eQTL eQTLgen omic data for AD is rs67501853, which has a multi-SNP SMR p-value of 3.95e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SPAG7" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1501918', 'topRSID': 'rs67501853', 'Disease': 'AD', 'Gene': 'SPAG7', 'p_SMR_multi': 3.950234e-07, 'p_HEIDI': 2.47639e-05, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.892 | Q67 | What is the top-associated SNP of the gene HUS1 in Whole Brain meta-analysis mQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene HUS1 in Whole Brain meta-analysis mQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "HUS1" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_262643', 'topRSID': 'rs953595', 'Disease': 'FTD', 'Gene': 'HUS1', 'p_SMR_multi': 0.0002480574, 'p_HEIDI': 0.9187705, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.82 | Q67 | What is the top-associated SNP of the gene SNX24 in Nucleus Accumbens Basal Ganglia omic data for AD and is it functionally significant? | There are no SNPs within the gene SNX24 in Nucleus Accumbens Basal Ganglia omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SNX24" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%nucleus accumbens basal ganglia%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1715721', 'topRSID': 'rs35939166', 'Disease': 'AD', 'Gene': 'SNX24', 'p_SMR_multi': 0.5823782, 'p_HEIDI': 0.6388274, 'Omic_tissue': 'Nucleus Accumbens Basal', 'Omic_type': 'Nucleus Accumbens Basal Ganglia', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1182 | Q67 | What is the top-associated SNP of the gene C6orf10 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for C6orf10 in Whole Blood mQTL omic data for AD is rs35265698, which has a multi-SNP SMR p-value of 2.72e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "C6orf10" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_621662', 'topRSID': 'rs35265698', 'Disease': 'AD', 'Gene': 'C6orf10', 'p_SMR_multi': 2.929935e-08, 'p_HEIDI': 2.344082e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Di... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.821 | Q67 | What is the top-associated SNP of the gene RASGRF1 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene RASGRF1 in Whole Brain meta-analysis mQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RASGRF1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_106504', 'topRSID': 'rs7183818', 'Disease': 'AD', 'Gene': 'RASGRF1', 'p_SMR_multi': 0.001607408, 'p_HEIDI': 0.5329023, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_tex... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1283 | Q67 | What is the top-associated SNP of the gene AP2A2 in Whole Brain meta-analysis mQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene AP2A2 in Whole Brain meta-analysis mQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "AP2A2" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_277927', 'topRSID': 'rs10902271', 'Disease': 'FTD', 'Gene': 'AP2A2', 'p_SMR_multi': 0.125065, 'p_HEIDI': 0.3111974, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_2... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.678 | Q67 | What is the top-associated SNP of the gene MAPT in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD and is it functionally significant? | The top-associated SNP for MAPT in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD is rs62055936, which has a multi-SNP SMR p-value of 2.03e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1396748', 'topRSID': 'rs62055936', 'Disease': 'AD', 'Gene': 'MAPT', 'p_SMR_multi': 2.02904e-07, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance threshold bu... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1533 | Q67 | What is the top-associated SNP of the gene DGKQ in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for DGKQ in Whole Blood mQTL omic data for PD is rs10794537, which has a multi-SNP SMR p-value of 2.63e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DGKQ" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_996294', 'topRSID': 'rs2290402', 'Disease': 'PD', 'Gene': 'DGKQ', 'p_SMR_multi': 3.044298e-09, 'p_HEIDI': 1.349111e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.59 | Q67 | What is the top-associated SNP of the gene SPG7 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene SPG7 in Whole Brain meta-analysis mQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SPG7" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_112081', 'topRSID': 'rs74037226', 'Disease': 'AD', 'Gene': 'SPG7', 'p_SMR_multi': 0.008579452, 'p_HEIDI': 0.3807884, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.136 | Q67 | What is the top-associated SNP of the gene PDE9A in Whole Brain meta-analysis mQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene PDE9A in Whole Brain meta-analysis mQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PDE9A" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_407057', 'topRSID': 'rs2269139', 'Disease': 'LBD', 'Gene': 'PDE9A', 'p_SMR_multi': 0.1792636, 'p_HEIDI': 0.6960945, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_4... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1150 | Q67 | What is the top-associated SNP of the gene SLX4 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene SLX4 in Whole Brain meta-analysis mQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SLX4" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_484519', 'topRSID': 'rs74369366', 'Disease': 'PD', 'Gene': 'SLX4', 'p_SMR_multi': 0.1426388, 'p_HEIDI': 0.4722708, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_48... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.942 | Q67 | What is the top-associated SNP of the gene HCG17 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene HCG17 in Whole Brain meta-analysis mQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "HCG17" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_64930', 'topRSID': 'rs7740823', 'Disease': 'AD', 'Gene': 'HCG17', 'p_SMR_multi': 0.001116117, 'p_HEIDI': 0.5649002, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_6... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1685 | Q67 | What is the top-associated SNP of the gene SLC25A37 in Tibial Nerve eQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene SLC25A37 in Tibial Nerve eQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SLC25A37" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1325303', 'topRSID': 'rs7844887', 'Disease': 'PD', 'Gene': 'SLC25A37', 'p_SMR_multi': 0.4269245, 'p_HEIDI': 0.1366204, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.830 | Q67 | What is the top-associated SNP of the gene CASP8AP2 in Whole Brain meta-analysis mQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene CASP8AP2 in Whole Brain meta-analysis mQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CASP8AP2" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_349674', 'topRSID': 'rs2777852', 'Disease': 'LBD', 'Gene': 'CASP8AP2', 'p_SMR_multi': 0.3837908, 'p_HEIDI': 0.197734, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1224 | Q67 | What is the top-associated SNP of the gene TBX6 in Cortex eQTL metaBrain omic data for AD and is it functionally significant? | The top-associated SNP for TBX6 in Cortex eQTL metaBrain omic data for AD is rs3809627, which has a multi-SNP SMR p-value of 4.17e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TBX6" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1111647', 'topRSID': 'rs3809627', 'Disease': 'AD', 'Gene': 'TBX6', 'p_SMR_multi': 4.169908e-07, 'p_HEIDI': 0.0001585194, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.510 | Q67 | What is the top-associated SNP of the gene FBXL18 in Whole Blood mQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene FBXL18 in Whole Blood mQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "FBXL18" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_807242', 'topRSID': 'rs6975264', 'Disease': 'FTD', 'Gene': 'FBXL18', 'p_SMR_multi': 0.1864882, 'p_HEIDI': 0.5611549, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_807271', 'topR... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1776 | Q67 | What is the top-associated SNP of the gene CPLX1 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for CPLX1 in Whole Blood mQTL omic data for AD is rs6848474, which has a multi-SNP SMR p-value of 7.32e-07 and a HEIDI of 0.2, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CPLX1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_657229', 'topRSID': 'rs6848474', 'Disease': 'AD', 'Gene': 'CPLX1', 'p_SMR_multi': 7.32026e-07, 'p_HEIDI': 0.2040095, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_657230', 'topRSID'... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.351 | Q67 | What is the top-associated SNP of the gene SMYD3 in Whole Brain meta-analysis mQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene SMYD3 in Whole Brain meta-analysis mQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SMYD3" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_233763', 'topRSID': 'rs2153401', 'Disease': 'FTD', 'Gene': 'SMYD3', 'p_SMR_multi': 0.004537356, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_2... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.392 | Q67 | What is the top-associated SNP of the gene CCDC81 in Whole Blood mQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene CCDC81 in Whole Blood mQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CCDC81" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_801935', 'topRSID': 'rs7944482', 'Disease': 'FTD', 'Gene': 'CCDC81', 'p_SMR_multi': 0.2763418, 'p_HEIDI': 0.1367052, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_801937', 'topR... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1033 | Q67 | What is the top-associated SNP of the gene STYX in Skeletal Muscle eQTL omic data for AD and is it functionally significant? | The top-associated SNP for STYX in Skeletal Muscle eQTL omic data for AD is rs77690283, which has a multi-SNP SMR p-value of 8.21e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "STYX" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1342185', 'topRSID': 'rs77690283', 'Disease': 'AD', 'Gene': 'STYX', 'p_SMR_multi': 8.214654e-08, 'p_HEIDI': 0.005807537, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linka... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.901 | Q67 | What is the top-associated SNP of the gene KANSL1 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for KANSL1 in Whole Brain meta-analysis mQTL omic data for PD is rs62060852, which has a multi-SNP SMR p-value of 5.11e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491139', 'topRSID': 'rs12150087', 'Disease': 'PD', 'Gene': 'KANSL1', 'p_SMR_multi': 8.107128999999999e-20, 'p_HEIDI': 0.009069932, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs o... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.835 | Q67 | What is the top-associated SNP of the gene PVRL2 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for PVRL2 in Whole Blood mQTL omic data for AD is rs1871046, which has a multi-SNP SMR p-value of 1.56e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PVRL2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_637426', 'topRSID': 'rs149529419', 'Disease': 'AD', 'Gene': 'PVRL2', 'p_SMR_multi': 5.514291e-09, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequil... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1894 | Q67 | What is the top-associated SNP of the gene PM20D1 in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for PM20D1 in Whole Blood mQTL omic data for PD is rs1772143, which has a multi-SNP SMR p-value of 8.41e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PM20D1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_944692', 'topRSID': 'rs823080', 'Disease': 'PD', 'Gene': 'PM20D1', 'p_SMR_multi': 7.078994e-07, 'p_HEIDI': 1.577211e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.481 | Q67 | What is the top-associated SNP of the gene AVL9 in Whole Blood mQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene AVL9 in Whole Blood mQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "AVL9" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_726406', 'topRSID': 'rs115576388', 'Disease': 'ALS', 'Gene': 'AVL9', 'p_SMR_multi': 0.3041238, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_726401', 'topRSI... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1472 | Q67 | What is the top-associated SNP of the gene CAT in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene CAT in Whole Brain meta-analysis mQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CAT" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_466744', 'topRSID': 'rs524167', 'Disease': 'PD', 'Gene': 'CAT', 'p_SMR_multi': 0.2192965, 'p_HEIDI': 0.3112412, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_46674... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1887 | Q67 | What is the top-associated SNP of the gene ZSCAN9 in Whole Blood eQTL GTEx omic data for LBD and is it functionally significant? | There are no SNPs within the gene ZSCAN9 in Whole Blood eQTL GTEx omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ZSCAN9" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole blood eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1669446', 'topRSID': 'rs12201260', 'Disease': 'LBD', 'Gene': 'ZSCAN9', 'p_SMR_multi': 0.2558696, 'p_HEIDI': 0.4445478, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL GTEx', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1398 | Q67 | What is the top-associated SNP of the gene STAG3 in Putamen Basal Ganglia eQTL omic data for AD and is it functionally significant? | The top-associated SNP for STAG3 in Putamen Basal Ganglia eQTL omic data for AD is rs858513, which has a multi-SNP SMR p-value of 1.49e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "STAG3" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%putamen basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1583221', 'topRSID': 'rs858513', 'Disease': 'AD', 'Gene': 'STAG3', 'p_SMR_multi': 1.4876e-07, 'p_HEIDI': 4.61023e-05, 'Omic_tissue': 'Putamen Basal Ganglia', 'Omic_type': 'Putamen Basal Ganglia eQTL', 'func_sig': 'association meets significance threshold but shows signs of linka... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.659 | Q67 | What is the top-associated SNP of the gene ARL17B in Cortex eQTL metaBrain omic data for PD and is it functionally significant? | The top-associated SNP for ARL17B in Cortex eQTL metaBrain omic data for PD is rs538628, which has a multi-SNP SMR p-value of 3.17e-15 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17B" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1147258', 'topRSID': 'rs538628', 'Disease': 'PD', 'Gene': 'ARL17B', 'p_SMR_multi': 3.171945e-15, 'p_HEIDI': 5.176024e-06, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dise... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.175 | Q67 | What is the top-associated SNP of the gene IRF5 in Whole Brain eQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene IRF5 in Whole Brain eQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "IRF5" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1637212', 'topRSID': 'rs11763684', 'Disease': 'PD', 'Gene': 'IRF5', 'p_SMR_multi': 0.5448558, 'p_HEIDI': 0.2779288, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1159 | Q67 | What is the top-associated SNP of the gene SRP54 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene SRP54 in Whole Brain meta-analysis mQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SRP54" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_102135', 'topRSID': 'rs112468160', 'Disease': 'AD', 'Gene': 'SRP54', 'p_SMR_multi': 0.5256169, 'p_HEIDI': 0.875621, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_1... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.39 | Q67 | What is the top-associated SNP of the gene CTB-171A8.1 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for CTB-171A8.1 in Whole Brain meta-analysis mQTL omic data for AD is rs2965164, which has a multi-SNP SMR p-value of 2.84e-06 and a HEIDI of 0.15, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CTB-171A8.1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_122446', 'topRSID': 'rs10410915', 'Disease': 'AD', 'Gene': 'CTB-171A8.1', 'p_SMR_multi': 3.296369e-08, 'p_HEIDI': 0.0001542126, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of l... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.720 | Q67 | What is the top-associated SNP of the gene RP11-259G18.1 in Nucleus Accumbens Basal Ganglia omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-259G18.1 in Nucleus Accumbens Basal Ganglia omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 1.95e-14 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%nucleus accumbens basal ganglia%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1732398', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'RP11-259G18.1', 'p_SMR_multi': 1.946116e-14, 'p_HEIDI': 4.491428e-14, 'Omic_tissue': 'Nucleus Accumbens Basal', 'Omic_type': 'Nucleus Accumbens Basal Ganglia', 'func_sig': 'association meets significance threshold but ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.93 | Q67 | What is the top-associated SNP of the gene CLU in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for CLU in Whole Brain meta-analysis mQTL omic data for AD is rs10091215, which has a multi-SNP SMR p-value of 1.36e-06 and a HEIDI of 0.03, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CLU" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_78262', 'topRSID': 'rs7982', 'Disease': 'AD', 'Gene': 'CLU', 'p_SMR_multi': 2.501744e-10, 'p_HEIDI': 6.84878e-05, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1937 | Q67 | What is the top-associated SNP of the gene AC009802.1 in Whole Blood mQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene AC009802.1 in Whole Blood mQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "AC009802.1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1014943', 'topRSID': 'rs11152409', 'Disease': 'PD', 'Gene': 'AC009802.1', 'p_SMR_multi': 0.3778673, 'p_HEIDI': 0.1586075, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_1014940',... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1215 | Q67 | What is the top-associated SNP of the gene PILRB in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD and is it functionally significant? | The top-associated SNP for PILRB in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD is rs2897358, which has a multi-SNP SMR p-value of 1.21e-09 and a HEIDI of 0.07, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PILRB" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1392628', 'topRSID': 'rs2897358', 'Disease': 'AD', 'Gene': 'PILRB', 'p_SMR_multi': 1.205748e-09, 'p_HEIDI': 0.06583308, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.882 | Q67 | What is the top-associated SNP of the gene RP11-259G18.3 in Whole Brain eQTL omic data for AD and is it functionally significant? | The top-associated SNP for RP11-259G18.3 in Whole Brain eQTL omic data for AD is rs199533, which has a multi-SNP SMR p-value of 2.13e-06 and a HEIDI of 0.11, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.3" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1610868', 'topRSID': 'rs199533', 'Disease': 'AD', 'Gene': 'RP11-259G18.3', 'p_SMR_multi': 2.129162e-06, 'p_HEIDI': 0.1089491, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1353 | Q67 | What is the top-associated SNP of the gene LAMTOR4 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for LAMTOR4 in Whole Blood eQTL eQTLgen omic data for AD is rs12878, which has a multi-SNP SMR p-value of 2.04e-12 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LAMTOR4" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1495796', 'topRSID': 'rs12878', 'Disease': 'AD', 'Gene': 'LAMTOR4', 'p_SMR_multi': 2.035005e-12, 'p_HEIDI': 7.438358e-07, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1891 | Q67 | What is the top-associated SNP of the gene DPY19L1P1 in Cerebellar Hemisphere eQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene DPY19L1P1 in Cerebellar Hemisphere eQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DPY19L1P1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cerebellar hemisphere eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1172770', 'topRSID': 'rs6974642', 'Disease': 'AD', 'Gene': 'DPY19L1P1', 'p_SMR_multi': 0.06828847, 'p_HEIDI': 0.1955849, 'Omic_tissue': 'Cerebellar Hemisphere', 'Omic_type': 'Cerebellar Hemisphere eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1102 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for MAPT in Whole Blood mQTL omic data for PD is rs112572874, which has a multi-SNP SMR p-value of 1.61e-14 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_948891', 'topRSID': 'rs62063271', 'Disease': 'PD', 'Gene': 'MAPT', 'p_SMR_multi': 6.382411e-15, 'p_HEIDI': 2.368028e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1165 | Q67 | What is the top-associated SNP of the gene RP11-259G18.3 in Tibial Nerve eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-259G18.3 in Tibial Nerve eQTL omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 8.68e-31 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.3" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1336293', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'RP11-259G18.3', 'p_SMR_multi': 8.684303e-31, 'p_HEIDI': 1.411049e-09, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Li... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1365 | Q67 | What is the top-associated SNP of the gene CPLX1 in Whole Blood mQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene CPLX1 in Whole Blood mQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CPLX1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_996235', 'topRSID': 'rs3088106', 'Disease': 'PD', 'Gene': 'CPLX1', 'p_SMR_multi': 2.945018e-07, 'p_HEIDI': 0.0008254259, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1959 | Q67 | What is the top-associated SNP of the gene FN3KRP in Spinalcord eQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene FN3KRP in Spinalcord eQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "FN3KRP" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%spinalcord eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_29913', 'topRSID': 'rs2246577', 'Disease': 'LBD', 'Gene': 'FN3KRP', 'p_SMR_multi': 0.3210627, 'p_HEIDI': 0.178851, 'Omic_tissue': 'Spinalcord', 'Omic_type': 'Spinalcord eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.505 | Q67 | What is the top-associated SNP of the gene FAM190A in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for FAM190A in Whole Blood mQTL omic data for PD is rs1835524, which has a multi-SNP SMR p-value of 2.66e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "FAM190A" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_998616', 'topRSID': 'rs1835524', 'Disease': 'PD', 'Gene': 'FAM190A', 'p_SMR_multi': 2.663993e-07, 'p_HEIDI': 0.0001542441, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.342 | Q67 | What is the top-associated SNP of the gene FAM193B in Skeletal Muscle eQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene FAM193B in Skeletal Muscle eQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "FAM193B" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1360210', 'topRSID': 'rs1990909', 'Disease': 'LBD', 'Gene': 'FAM193B', 'p_SMR_multi': 0.2546303, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1198 | Q67 | What is the top-associated SNP of the gene RP11-259G18.2 in Whole Blood eQTL GTEx omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-259G18.2 in Whole Blood eQTL GTEx omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 3.80e-33 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.2" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1684936', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'RP11-259G18.2', 'p_SMR_multi': 3.800151e-33, 'p_HEIDI': 4.935575e-18, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL GTEx', 'func_sig': 'association meets significance threshold but shows signs of linkage/... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.29 | Q67 | What is the top-associated SNP of the gene CRHR1 in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for CRHR1 in Whole Blood mQTL omic data for PD is rs113790915, which has a multi-SNP SMR p-value of 5.27e-12 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CRHR1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_948861', 'topRSID': 'rs17689882', 'Disease': 'PD', 'Gene': 'CRHR1', 'p_SMR_multi': 8.633399e-15, 'p_HEIDI': 7.397796e-05, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dise... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1227 | Q67 | What is the top-associated SNP of the gene RNPEP in Whole Brain meta-analysis mQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene RNPEP in Whole Brain meta-analysis mQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RNPEP" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_232244', 'topRSID': 'rs13375435', 'Disease': 'FTD', 'Gene': 'RNPEP', 'p_SMR_multi': 0.3839052, 'p_HEIDI': 0.450258, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_2... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1434 | Q67 | What is the top-associated SNP of the gene BIN1 in Whole Blood eQTL GTEx omic data for AD and is it functionally significant? | The top-associated SNP for BIN1 in Whole Blood eQTL GTEx omic data for AD is rs11694743, which has a multi-SNP SMR p-value of 2.01e-14 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "BIN1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1647997', 'topRSID': 'rs11694743', 'Disease': 'AD', 'Gene': 'BIN1', 'p_SMR_multi': 2.013386e-14, 'p_HEIDI': 3.821633e-16, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL GTEx', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1954 | Q67 | What is the top-associated SNP of the gene RP11-259G18.2 in Cerebellar Hemisphere eQTL omic data for AD and is it functionally significant? | The top-associated SNP for RP11-259G18.2 in Cerebellar Hemisphere eQTL omic data for AD is rs17763086, which has a multi-SNP SMR p-value of 2.95e-06 and a HEIDI of 0.72, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cerebellar hemisphere eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1174599', 'topRSID': 'rs17763086', 'Disease': 'AD', 'Gene': 'RP11-259G18.2', 'p_SMR_multi': 2.948594e-06, 'p_HEIDI': 0.7176842, 'Omic_tissue': 'Cerebellar Hemisphere', 'Omic_type': 'Cerebellar Hemisphere eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.954 | Q67 | What is the top-associated SNP of the gene RP11-259G18.2 in Hypothalamus eQTL omic data for PD and is it functionally significant? | The top-associated SNP for RP11-259G18.2 in Hypothalamus eQTL omic data for PD is rs199533, which has a multi-SNP SMR p-value of 1.02e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.2" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%hypothalamus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1462896', 'topRSID': 'rs199533', 'Disease': 'PD', 'Gene': 'RP11-259G18.2', 'p_SMR_multi': 1.020137e-10, 'p_HEIDI': 0.0005136639, 'Omic_tissue': 'Hypothalamus', 'Omic_type': 'Hypothalamus eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Lin... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.172 | Q67 | What is the top-associated SNP of the gene ZNF837 in Whole Brain meta-analysis mQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene ZNF837 in Whole Brain meta-analysis mQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ZNF837" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_219907', 'topRSID': 'rs3794975', 'Disease': 'ALS', 'Gene': 'ZNF837', 'p_SMR_multi': 0.3930499, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_21... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1406 | Q67 | What is the top-associated SNP of the gene F10 in Whole Blood mQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene F10 in Whole Blood mQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "F10" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_953948', 'topRSID': 'rs7327099', 'Disease': 'PD', 'Gene': 'F10', 'p_SMR_multi': 0.2228987, 'p_HEIDI': 0.2731504, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_953944', 'topRSID'... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1207 | Q67 | What is the top-associated SNP of the gene LRRC37A2 in Cortex eQTL metaBrain omic data for PD and is it functionally significant? | The top-associated SNP for LRRC37A2 in Cortex eQTL metaBrain omic data for PD is rs2696466, which has a multi-SNP SMR p-value of 6.37e-16 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A2" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1147259', 'topRSID': 'rs2696466', 'Disease': 'PD', 'Gene': 'LRRC37A2', 'p_SMR_multi': 6.374703e-16, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1263 | Q67 | What is the top-associated SNP of the gene DOC2A in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for DOC2A in Whole Blood mQTL omic data for AD is rs11642740, which has a multi-SNP SMR p-value of 3.62e-08 and a HEIDI of 0.48, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DOC2A" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_577418', 'topRSID': 'rs12921753', 'Disease': 'AD', 'Gene': 'DOC2A', 'p_SMR_multi': 5.575261e-12, 'p_HEIDI': 0.3441697, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_577427', 'topRSI... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1400 | Q67 | What is the top-associated SNP of the gene DYDC1 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for DYDC1 in Whole Blood mQTL omic data for AD is rs10749575, which has a multi-SNP SMR p-value of 1.13e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DYDC1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_572625', 'topRSID': 'rs10749575', 'Disease': 'AD', 'Gene': 'DYDC1', 'p_SMR_multi': 8.563031e-07, 'p_HEIDI': 0.02305442, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_572626', 'topRS... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.920 | Q67 | What is the top-associated SNP of the gene ARHGAP27 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for ARHGAP27 in Whole Brain meta-analysis mQTL omic data for PD is rs1230106, which has a multi-SNP SMR p-value of 1.60e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARHGAP27" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491057', 'topRSID': 'rs62065376', 'Disease': 'PD', 'Gene': 'ARHGAP27', 'p_SMR_multi': 1.134698e-11, 'p_HEIDI': 0.3072466, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.497 | Q67 | What is the top-associated SNP of the gene LRRC37A4P in Frontal Cortex BA9 eQTL omic data for PD and is it functionally significant? | The top-associated SNP for LRRC37A4P in Frontal Cortex BA9 eQTL omic data for PD is rs62057151, which has a multi-SNP SMR p-value of 2.03e-12 and a HEIDI of 0.75, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A4P" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%frontal cortex ba9 eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1168831', 'topRSID': 'rs62057151', 'Disease': 'PD', 'Gene': 'LRRC37A4P', 'p_SMR_multi': 2.026026e-12, 'p_HEIDI': 0.7481131, 'Omic_tissue': 'Frontal Cortex', 'Omic_type': 'Frontal Cortex BA9 eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.962 | Q67 | What is the top-associated SNP of the gene LRRC37A2 in Cerebellar Hemisphere eQTL omic data for PD and is it functionally significant? | The top-associated SNP for LRRC37A2 in Cerebellar Hemisphere eQTL omic data for PD is rs56046792, which has a multi-SNP SMR p-value of 8.42e-12 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A2" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cerebellar hemisphere eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1191179', 'topRSID': 'rs56046792', 'Disease': 'PD', 'Gene': 'LRRC37A2', 'p_SMR_multi': 8.423566e-12, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Cerebellar Hemisphere', 'Omic_type': 'Cerebellar Hemisphere eQTL', 'func_sig': 'association meets significance threshold but shows signs of li... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1106 | Q67 | What is the top-associated SNP of the gene MYO7A in Whole Blood mQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene MYO7A in Whole Blood mQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MYO7A" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_610160', 'topRSID': 'rs7104633', 'Disease': 'AD', 'Gene': 'MYO7A', 'p_SMR_multi': 0.1984386, 'p_HEIDI': 0.3649548, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_610170', 'topRSI... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1041 | Q67 | What is the top-associated SNP of the gene IQCB1 in Hippocampus eQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene IQCB1 in Hippocampus eQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "IQCB1" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%hippocampus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1383573', 'topRSID': 'rs7642303', 'Disease': 'LBD', 'Gene': 'IQCB1', 'p_SMR_multi': 0.5816485, 'p_HEIDI': 0.2886984, 'Omic_tissue': 'Hippocampus', 'Omic_type': 'Hippocampus eQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_32546', 'topRS... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.594 | Q67 | What is the top-associated SNP of the gene KANSL1-AS1 in Hippocampus eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for KANSL1-AS1 in Hippocampus eQTL omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 1.95e-17 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1-AS1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%hippocampus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1388482', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'KANSL1-AS1', 'p_SMR_multi': 1.9528980000000002e-17, 'p_HEIDI': 5.270543e-09, 'Omic_tissue': 'Hippocampus', 'Omic_type': 'Hippocampus eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.757 | Q67 | What is the top-associated SNP of the gene KANSL1-AS1 in Frontal Cortex BA9 eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for KANSL1-AS1 in Frontal Cortex BA9 eQTL omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 1.82e-18 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1-AS1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%frontal cortex ba9 eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1170873', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'KANSL1-AS1', 'p_SMR_multi': 1.818021e-18, 'p_HEIDI': 4.818611e-13, 'Omic_tissue': 'Frontal Cortex', 'Omic_type': 'Frontal Cortex BA9 eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.664 | Q67 | What is the top-associated SNP of the gene LRRC37A2 in Tibial Nerve eQTL omic data for PD and is it functionally significant? | The top-associated SNP for LRRC37A2 in Tibial Nerve eQTL omic data for PD is rs62062768, which has a multi-SNP SMR p-value of 3.98e-13 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A2" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1328941', 'topRSID': 'rs62062768', 'Disease': 'PD', 'Gene': 'LRRC37A2', 'p_SMR_multi': 3.984119e-13, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.237 | Q67 | What is the top-associated SNP of the gene C6orf10 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for C6orf10 in Whole Blood mQTL omic data for AD is rs116667074, which has a multi-SNP SMR p-value of 1.10e-07 and a HEIDI of 0.04, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "C6orf10" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_621662', 'topRSID': 'rs35265698', 'Disease': 'AD', 'Gene': 'C6orf10', 'p_SMR_multi': 2.929935e-08, 'p_HEIDI': 2.344082e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Di... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.739 | Q67 | What is the top-associated SNP of the gene FMNL1 in Cerebellar Hemisphere eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for FMNL1 in Cerebellar Hemisphere eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 5.05e-14 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "FMNL1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%cerebellar hemisphere eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1194207', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'FMNL1', 'p_SMR_multi': 5.049675e-14, 'p_HEIDI': 1.93655e-11, 'Omic_tissue': 'Cerebellar Hemisphere', 'Omic_type': 'Cerebellar Hemisphere eQTL', 'func_sig': 'association meets significance threshold but shows signs of l... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1989 | Q67 | What is the top-associated SNP of the gene GRM2 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | There are no SNPs within the gene GRM2 in Whole Blood eQTL eQTLgen omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GRM2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1492729', 'topRSID': 'rs1055429', 'Disease': 'AD', 'Gene': 'GRM2', 'p_SMR_multi': 0.006210617, 'p_HEIDI': 0.09542052, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1633 | Q67 | What is the top-associated SNP of the gene HOOK2 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene HOOK2 in Whole Brain meta-analysis mQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "HOOK2" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_496670', 'topRSID': 'rs897804', 'Disease': 'PD', 'Gene': 'HOOK2', 'p_SMR_multi': 0.1203272, 'p_HEIDI': 0.7849112, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_496... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1166 | Q67 | What is the top-associated SNP of the gene LRRC37A2 in Whole Blood eQTL GTEx omic data for PD and is it functionally significant? | The top-associated SNP for LRRC37A2 in Whole Blood eQTL GTEx omic data for PD is rs1724390, which has a multi-SNP SMR p-value of 7.75e-12 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A2" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1679572', 'topRSID': 'rs1724390', 'Disease': 'PD', 'Gene': 'LRRC37A2', 'p_SMR_multi': 7.75363e-12, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL GTEx', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Di... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1471 | Q67 | What is the top-associated SNP of the gene PVR in Skeletal Muscle eQTL omic data for AD and is it functionally significant? | The top-associated SNP for PVR in Skeletal Muscle eQTL omic data for AD is rs2301275, which has a multi-SNP SMR p-value of 9.95e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PVR" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1343792', 'topRSID': 'rs2301275', 'Disease': 'AD', 'Gene': 'PVR', 'p_SMR_multi': 9.947298e-09, 'p_HEIDI': 2.892447e-05, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1913 | Q67 | What is the top-associated SNP of the gene TMEM163 in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for TMEM163 in Whole Blood mQTL omic data for PD is rs57891859, which has a multi-SNP SMR p-value of 2.00e-06 and a HEIDI of 0.18, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TMEM163" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1019152', 'topRSID': 'rs57891859', 'Disease': 'PD', 'Gene': 'TMEM163', 'p_SMR_multi': 1.998553e-06, 'p_HEIDI': 0.1848392, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_1019149', 'to... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1628 | Q67 | What is the top-associated SNP of the gene MAPT-AS1 in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for MAPT-AS1 in Whole Blood mQTL omic data for PD is rs62056790, which has a multi-SNP SMR p-value of 1.73e-06 and a HEIDI of 0.11, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT-AS1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_948871', 'topRSID': 'rs78026984', 'Disease': 'PD', 'Gene': 'MAPT-AS1', 'p_SMR_multi': 1.185713e-13, 'p_HEIDI': 1.052222e-05, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage D... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.943 | Q67 | What is the top-associated SNP of the gene GPC6 in Whole Blood mQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene GPC6 in Whole Blood mQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GPC6" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_931232', 'topRSID': 'rs17300031', 'Disease': 'LBD', 'Gene': 'GPC6', 'p_SMR_multi': 0.2303086, 'p_HEIDI': 0.5287904, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_931247', 'topRS... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1219 | Q67 | What is the top-associated SNP of the gene RP11-259G18.3 in Whole Blood eQTL eQTLgen omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-259G18.3 in Whole Blood eQTL eQTLgen omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 2.67e-41 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.3" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1579424', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'RP11-259G18.3', 'p_SMR_multi': 2.66922e-41, 'p_HEIDI': 4.407001e-05, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1074 | Q67 | What is the top-associated SNP of the gene BIN1 in Cerebellar Hemisphere eQTL omic data for AD and is it functionally significant? | The top-associated SNP for BIN1 in Cerebellar Hemisphere eQTL omic data for AD is rs4663100, which has a multi-SNP SMR p-value of 2.38e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "BIN1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cerebellar hemisphere eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1171776', 'topRSID': 'rs4663100', 'Disease': 'AD', 'Gene': 'BIN1', 'p_SMR_multi': 2.3819e-08, 'p_HEIDI': 1.102427e-10, 'Omic_tissue': 'Cerebellar Hemisphere', 'Omic_type': 'Cerebellar Hemisphere eQTL', 'func_sig': 'association meets significance threshold but shows signs of link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.111 | Q67 | What is the top-associated SNP of the gene PVRIG in Hippocampus eQTL omic data for AD and is it functionally significant? | The top-associated SNP for PVRIG in Hippocampus eQTL omic data for AD is rs1617502, which has a multi-SNP SMR p-value of 3.49e-07 and a HEIDI of 0.19, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PVRIG" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%hippocampus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1377708', 'topRSID': 'rs1617502', 'Disease': 'AD', 'Gene': 'PVRIG', 'p_SMR_multi': 3.493793e-07, 'p_HEIDI': 0.1861916, 'Omic_tissue': 'Hippocampus', 'Omic_type': 'Hippocampus eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1944 | Q67 | What is the top-associated SNP of the gene RP11-259G18.3 in Putamen Basal Ganglia eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-259G18.3 in Putamen Basal Ganglia eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 2.82e-18 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.3" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%putamen basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1596824', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'RP11-259G18.3', 'p_SMR_multi': 2.823399e-18, 'p_HEIDI': 1.1301979999999999e-20, 'Omic_tissue': 'Putamen Basal Ganglia', 'Omic_type': 'Putamen Basal Ganglia eQTL', 'func_sig': 'association meets significance threshold b... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.574 | Q67 | What is the top-associated SNP of the gene AC097724.3 in Whole Brain meta-analysis mQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene AC097724.3 in Whole Brain meta-analysis mQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "AC097724.3" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_326691', 'topRSID': 'rs4408686', 'Disease': 'LBD', 'Gene': 'AC097724.3', 'p_SMR_multi': 0.4506275, 'p_HEIDI': 0.6613219, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1177 | Q67 | What is the top-associated SNP of the gene FBXL5 in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for FBXL5 in Whole Blood mQTL omic data for PD is rs6850422, which has a multi-SNP SMR p-value of 2.39e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "FBXL5" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_997634', 'topRSID': 'rs6850422', 'Disease': 'PD', 'Gene': 'FBXL5', 'p_SMR_multi': 2.394558e-06, 'p_HEIDI': 3.434998e-05, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1184 | Q67 | What is the top-associated SNP of the gene EPHA1-AS1 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for EPHA1-AS1 in Whole Blood eQTL eQTLgen omic data for AD is rs3935067, which has a multi-SNP SMR p-value of 3.91e-11 and a HEIDI of 0.04, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "EPHA1-AS1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1496073', 'topRSID': 'rs3935067', 'Disease': 'AD', 'Gene': 'EPHA1-AS1', 'p_SMR_multi': 3.914159e-11, 'p_HEIDI': 0.03719332, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.897 | Q67 | What is the top-associated SNP of the gene ANKRD13D in Whole Blood eQTL GTEx omic data for LBD and is it functionally significant? | There are no SNPs within the gene ANKRD13D in Whole Blood eQTL GTEx omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ANKRD13D" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole blood eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1671109', 'topRSID': 'rs3909167', 'Disease': 'LBD', 'Gene': 'ANKRD13D', 'p_SMR_multi': 0.6904297, 'p_HEIDI': 0.8343133, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL GTEx', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.956 | Q67 | What is the top-associated SNP of the gene FAM134B in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene FAM134B in Multi Ancestry Whole Brain Meta-analysis eQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "FAM134B" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 1... | [{'UUID': 'NDD_SMR_genes_all_update_text_1420844', 'topRSID': 'rs380796', 'Disease': 'LBD', 'Gene': 'FAM134B', 'p_SMR_multi': 0.05337506, 'p_HEIDI': 0.0651042, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1057 | Q67 | What is the top-associated SNP of the gene RP11-259G18.3 in Amygdala eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-259G18.3 in Amygdala eQTL omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 2.53e-15 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.3" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%amygdala eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1604715', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'RP11-259G18.3', 'p_SMR_multi': 2.52599e-15, 'p_HEIDI': 4.420346e-10, 'Omic_tissue': 'Amygdala', 'Omic_type': 'Amygdala eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1354 | Q67 | What is the top-associated SNP of the gene ADAMTS2 in Whole Brain meta-analysis mQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene ADAMTS2 in Whole Brain meta-analysis mQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ADAMTS2" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_344740', 'topRSID': 'rs112071001', 'Disease': 'LBD', 'Gene': 'ADAMTS2', 'p_SMR_multi': 0.07449829, 'p_HEIDI': 0.9064817, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_t... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1373 | Q67 | What is the top-associated SNP of the gene CCDC63 in Whole Brain meta-analysis mQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene CCDC63 in Whole Brain meta-analysis mQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CCDC63" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_193021', 'topRSID': 'rs2339635', 'Disease': 'ALS', 'Gene': 'CCDC63', 'p_SMR_multi': 0.1809598, 'p_HEIDI': 0.6643528, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1448 | Q67 | What is the top-associated SNP of the gene CEACAM16 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for CEACAM16 in Whole Brain meta-analysis mQTL omic data for AD is rs7248283, which has a multi-SNP SMR p-value of 2.79e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CEACAM16" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_122450', 'topRSID': 'rs7248283', 'Disease': 'AD', 'Gene': 'CEACAM16', 'p_SMR_multi': 2.793047e-10, 'p_HEIDI': 1.379269e-15, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linka... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.891 | Q67 | What is the top-associated SNP of the gene ADORA2B in Skeletal Muscle eQTL omic data for PD and is it functionally significant? | The top-associated SNP for ADORA2B in Skeletal Muscle eQTL omic data for PD is rs1045599, which has a multi-SNP SMR p-value of 2.73e-06 and a HEIDI of 0.02, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ADORA2B" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1370421', 'topRSID': 'rs1045599', 'Disease': 'PD', 'Gene': 'ADORA2B', 'p_SMR_multi': 2.729232e-06, 'p_HEIDI': 0.0173546, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1673 | Q67 | What is the top-associated SNP of the gene ARHGAP27 in Whole Brain meta-analysis mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for ARHGAP27 in Whole Brain meta-analysis mQTL omic data for PSP is rs11012, which has a multi-SNP SMR p-value of 3.09e-13 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARHGAP27" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_560834', 'topRSID': 'rs11012', 'Disease': 'PSP', 'Gene': 'ARHGAP27', 'p_SMR_multi': 9.282341e-28, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Li... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.857 | Q67 | What is the top-associated SNP of the gene YPEL3 in Cerebellum eQTL omic data for AD and is it functionally significant? | The top-associated SNP for YPEL3 in Cerebellum eQTL omic data for AD is rs12444973, which has a multi-SNP SMR p-value of 7.25e-07 and a HEIDI of 0.08, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "YPEL3" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1689748', 'topRSID': 'rs12444973', 'Disease': 'AD', 'Gene': 'YPEL3', 'p_SMR_multi': 7.254515e-07, 'p_HEIDI': 0.07808286, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_2878', 'topRSID'... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.741 | Q67 | What is the top-associated SNP of the gene DGKQ in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for DGKQ in Whole Blood mQTL omic data for PD is rs1377586, which has a multi-SNP SMR p-value of 7.78e-07 and a HEIDI of 0.01, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DGKQ" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_996294', 'topRSID': 'rs2290402', 'Disease': 'PD', 'Gene': 'DGKQ', 'p_SMR_multi': 3.044298e-09, 'p_HEIDI': 1.349111e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.724 | Q67 | What is the top-associated SNP of the gene KANSL1-AS1 in Hippocampus eQTL omic data for PD and is it functionally significant? | The top-associated SNP for KANSL1-AS1 in Hippocampus eQTL omic data for PD is rs199533, which has a multi-SNP SMR p-value of 1.68e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1-AS1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%hippocampus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1386991', 'topRSID': 'rs199533', 'Disease': 'PD', 'Gene': 'KANSL1-AS1', 'p_SMR_multi': 1.677659e-11, 'p_HEIDI': 0.0007854035, 'Omic_tissue': 'Hippocampus', 'Omic_type': 'Hippocampus eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.460 | Q67 | What is the top-associated SNP of the gene C9orf72 in Whole Blood eQTL GTEx omic data for ALS and is it functionally significant? | The top-associated SNP for C9orf72 in Whole Blood eQTL GTEx omic data for ALS is rs10967981, which has a multi-SNP SMR p-value of 1.79e-07 and a HEIDI of 0.01, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "C9orf72" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole blood eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1656933', 'topRSID': 'rs10967981', 'Disease': 'ALS', 'Gene': 'C9orf72', 'p_SMR_multi': 1.787484e-07, 'p_HEIDI': 0.01318933, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL GTEx', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.267 | Q67 | What is the top-associated SNP of the gene PVRIG in Putamen Basal Ganglia eQTL omic data for AD and is it functionally significant? | The top-associated SNP for PVRIG in Putamen Basal Ganglia eQTL omic data for AD is rs1623264, which has a multi-SNP SMR p-value of 2.79e-07 and a HEIDI of 0.09, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PVRIG" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%putamen basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1583222', 'topRSID': 'rs1623264', 'Disease': 'AD', 'Gene': 'PVRIG', 'p_SMR_multi': 2.788121e-07, 'p_HEIDI': 0.08560628, 'Omic_tissue': 'Putamen Basal Ganglia', 'Omic_type': 'Putamen Basal Ganglia eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.78 | Q67 | What is the top-associated SNP of the gene KAT8 in Cortex eQTL metaBrain omic data for PD and is it functionally significant? | The top-associated SNP for KAT8 in Cortex eQTL metaBrain omic data for PD is rs2855475, which has a multi-SNP SMR p-value of 1.65e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KAT8" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1140854', 'topRSID': 'rs2855475', 'Disease': 'PD', 'Gene': 'KAT8', 'p_SMR_multi': 1.654424e-07, 'p_HEIDI': 0.009170133, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1785 | Q67 | What is the top-associated SNP of the gene C6orf10 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for C6orf10 in Whole Blood mQTL omic data for AD is rs601945, which has a multi-SNP SMR p-value of 7.03e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "C6orf10" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_621662', 'topRSID': 'rs35265698', 'Disease': 'AD', 'Gene': 'C6orf10', 'p_SMR_multi': 2.929935e-08, 'p_HEIDI': 2.344082e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Di... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
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