uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
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Q67.440 | Q67 | What is the top-associated SNP of the gene C7orf59 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for C7orf59 in Whole Blood mQTL omic data for AD is rs11771139, which has a multi-SNP SMR p-value of 3.98e-13 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "C7orf59" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_585977', 'topRSID': 'rs11771139', 'Disease': 'AD', 'Gene': 'C7orf59', 'p_SMR_multi': 3.977226e-13, 'p_HEIDI': 8.913888e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Di... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.77 | Q67 | What is the top-associated SNP of the gene LRRC37A2 in Whole Brain eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for LRRC37A2 in Whole Brain eQTL omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 1.45e-32 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A2" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1646050', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'LRRC37A2', 'p_SMR_multi': 1.448721e-32, 'p_HEIDI': 4.997206e-10, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage D... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1793 | Q67 | What is the top-associated SNP of the gene RP11-259G18.1 in Skeletal Muscle eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-259G18.1 in Skeletal Muscle eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 2.46e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1375932', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'RP11-259G18.1', 'p_SMR_multi': 2.463815e-07, 'p_HEIDI': 0.003782056, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'association meets significance threshold but shows signs of linka... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1462 | Q67 | What is the top-associated SNP of the gene SETD1A in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for SETD1A in Whole Brain meta-analysis mQTL omic data for PD is rs11150601, which has a multi-SNP SMR p-value of 3.40e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SETD1A" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_485446', 'topRSID': 'rs11150601', 'Disease': 'PD', 'Gene': 'SETD1A', 'p_SMR_multi': 3.404339e-07, 'p_HEIDI': 8.535299e-05, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.926 | Q67 | What is the top-associated SNP of the gene STX4 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for STX4 in Whole Blood eQTL eQTLgen omic data for AD is rs58726213, which has a multi-SNP SMR p-value of 1.06e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "STX4" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1501474', 'topRSID': 'rs58726213', 'Disease': 'AD', 'Gene': 'STX4', 'p_SMR_multi': 1.063079e-07, 'p_HEIDI': 4.202335e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1712 | Q67 | What is the top-associated SNP of the gene CRHR1-IT1 in Anterior Cingulate Cortex BA24 eQTL omic data for PD and is it functionally significant? | The top-associated SNP for CRHR1-IT1 in Anterior Cingulate Cortex BA24 eQTL omic data for PD is rs112560196, which has a multi-SNP SMR p-value of 9.91e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CRHR1-IT1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%anterior cingulate cortex ba24 eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1488138', 'topRSID': 'rs112560196', 'Disease': 'PD', 'Gene': 'CRHR1-IT1', 'p_SMR_multi': 9.91348e-11, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Anterior Cingulate Cortex BA24', 'Omic_type': 'Anterior Cingulate Cortex BA24 eQTL', 'func_sig': 'association meets significance threshold bu... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1671 | Q67 | What is the top-associated SNP of the gene MSC in Whole Brain meta-analysis mQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene MSC in Whole Brain meta-analysis mQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MSC" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_268209', 'topRSID': 'rs7812453', 'Disease': 'FTD', 'Gene': 'MSC', 'p_SMR_multi': 0.140711, 'p_HEIDI': 0.7173499, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_2682... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1621 | Q67 | What is the top-associated SNP of the gene PRDM7 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for PRDM7 in Whole Brain meta-analysis mQTL omic data for AD is rs34101249, which has a multi-SNP SMR p-value of 1.48e-06 and a HEIDI of 0.31, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PRDM7" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_112276', 'topRSID': 'rs34101249', 'Disease': 'AD', 'Gene': 'PRDM7', 'p_SMR_multi': 7.198016e-07, 'p_HEIDI': 0.1898645, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_11... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.769 | Q67 | What is the top-associated SNP of the gene ADSSL1 in Whole Brain meta-analysis mQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene ADSSL1 in Whole Brain meta-analysis mQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ADSSL1" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_292669', 'topRSID': 'rs4983541', 'Disease': 'FTD', 'Gene': 'ADSSL1', 'p_SMR_multi': 0.1437171, 'p_HEIDI': 0.4868584, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.998 | Q67 | What is the top-associated SNP of the gene CSTF1 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for CSTF1 in Whole Blood eQTL eQTLgen omic data for AD is rs6024857, which has a multi-SNP SMR p-value of 2.11e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CSTF1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1504669', 'topRSID': 'rs6024857', 'Disease': 'AD', 'Gene': 'CSTF1', 'p_SMR_multi': 2.112683e-10, 'p_HEIDI': 1.254673e-05, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.394 | Q67 | What is the top-associated SNP of the gene LRRC37A in Whole Brain eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for LRRC37A in Whole Brain eQTL omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 2.25e-34 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1646048', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'LRRC37A', 'p_SMR_multi': 2.247746e-34, 'p_HEIDI': 7.514554e-10, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Di... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.238 | Q67 | What is the top-associated SNP of the gene C17orf107 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for C17orf107 in Whole Blood mQTL omic data for AD is rs16954243, which has a multi-SNP SMR p-value of 3.80e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "C17orf107" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_589015', 'topRSID': 'rs16954243', 'Disease': 'AD', 'Gene': 'C17orf107', 'p_SMR_multi': 3.798115e-07, 'p_HEIDI': 0.008150263, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage D... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1508 | Q67 | What is the top-associated SNP of the gene PTPRG in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene PTPRG in Whole Brain meta-analysis mQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PTPRG" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_51141', 'topRSID': 'rs73093085', 'Disease': 'AD', 'Gene': 'PTPRG', 'p_SMR_multi': 0.07288933, 'p_HEIDI': 0.1740603, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_5... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.270 | Q67 | What is the top-associated SNP of the gene KANSL1 in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for KANSL1 in Whole Blood mQTL omic data for PD is rs117913167, which has a multi-SNP SMR p-value of 2.61e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_948907', 'topRSID': 'rs2532233', 'Disease': 'PD', 'Gene': 'KANSL1', 'p_SMR_multi': 1.024112e-14, 'p_HEIDI': 2.989456e-05, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dise... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1187 | Q67 | What is the top-associated SNP of the gene LRRC37A in Basal Ganglia eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for LRRC37A in Basal Ganglia eQTL omic data for PSP is rs7225002, which has a multi-SNP SMR p-value of 6.05e-13 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_27913', 'topRSID': 'rs7225002', 'Disease': 'PSP', 'Gene': 'LRRC37A', 'p_SMR_multi': 6.047793e-13, 'p_HEIDI': 2.29124e-08, 'Omic_tissue': 'Basal Ganglia', 'Omic_type': 'Basal Ganglia eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.120 | Q67 | What is the top-associated SNP of the gene ACADM in Whole Brain meta-analysis mQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene ACADM in Whole Brain meta-analysis mQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ACADM" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_229597', 'topRSID': 'rs80220597', 'Disease': 'FTD', 'Gene': 'ACADM', 'p_SMR_multi': 0.0202105, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_22... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1607 | Q67 | What is the top-associated SNP of the gene MMRN1 in Cortex eQTL GTEx omic data for PD and is it functionally significant? | The top-associated SNP for MMRN1 in Cortex eQTL GTEx omic data for PD is rs75943295, which has a multi-SNP SMR p-value of 8.19e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MMRN1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cortex eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1260051', 'topRSID': 'rs75943295', 'Disease': 'PD', 'Gene': 'MMRN1', 'p_SMR_multi': 8.189842e-07, 'p_HEIDI': 0.002125882, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL GTEx', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequili... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.680 | Q67 | What is the top-associated SNP of the gene ALKBH5 in Whole Blood mQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene ALKBH5 in Whole Blood mQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ALKBH5" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_589831', 'topRSID': 'rs62073606', 'Disease': 'AD', 'Gene': 'ALKBH5', 'p_SMR_multi': 0.003018779, 'p_HEIDI': 0.1342237, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_589830', 'to... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.252 | Q67 | What is the top-associated SNP of the gene LINC00665 in Cerebellum eQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene LINC00665 in Cerebellum eQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LINC00665" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1705658', 'topRSID': 'rs8106095', 'Disease': 'LBD', 'Gene': 'LINC00665', 'p_SMR_multi': 0.114796, 'p_HEIDI': 0.3386261, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1958 | Q67 | What is the top-associated SNP of the gene LRRC37A2 in Whole Brain eQTL omic data for PD and is it functionally significant? | The top-associated SNP for LRRC37A2 in Whole Brain eQTL omic data for PD is rs62641967, which has a multi-SNP SMR p-value of 7.65e-15 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A2" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1640229', 'topRSID': 'rs62641967', 'Disease': 'PD', 'Gene': 'LRRC37A2', 'p_SMR_multi': 7.646024e-15, 'p_HEIDI': 4.887099e-09, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1995 | Q67 | What is the top-associated SNP of the gene LRRC37A in Cerebellum eQTL omic data for AD and is it functionally significant? | The top-associated SNP for LRRC37A in Cerebellum eQTL omic data for AD is rs2696466, which has a multi-SNP SMR p-value of 2.13e-06 and a HEIDI of 0.52, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1690051', 'topRSID': 'rs4510068', 'Disease': 'AD', 'Gene': 'LRRC37A', 'p_SMR_multi': 1.056725e-06, 'p_HEIDI': 0.6262373, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_2658', 'topRSID'... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.97 | Q67 | What is the top-associated SNP of the gene MMRN1 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PD and is it functionally significant? | The top-associated SNP for MMRN1 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PD is rs79093919, which has a multi-SNP SMR p-value of 8.45e-15 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MMRN1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1430395', 'topRSID': 'rs79093919', 'Disease': 'PD', 'Gene': 'MMRN1', 'p_SMR_multi': 8.451387e-15, 'p_HEIDI': 1.293812e-06, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance thres... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.34 | Q67 | What is the top-associated SNP of the gene LRRC37A4P in Nucleus Accumbens Basal Ganglia omic data for PSP and is it functionally significant? | The top-associated SNP for LRRC37A4P in Nucleus Accumbens Basal Ganglia omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 3.33e-21 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A4P" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%nucleus accumbens basal ganglia%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1732390', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'LRRC37A4P', 'p_SMR_multi': 3.325569e-21, 'p_HEIDI': 1.435398e-25, 'Omic_tissue': 'Nucleus Accumbens Basal', 'Omic_type': 'Nucleus Accumbens Basal Ganglia', 'func_sig': 'association meets significance threshold but show... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1465 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for MAPT in Whole Blood mQTL omic data for PD is rs112746008, which has a multi-SNP SMR p-value of 2.27e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_948891', 'topRSID': 'rs62063271', 'Disease': 'PD', 'Gene': 'MAPT', 'p_SMR_multi': 6.382411e-15, 'p_HEIDI': 2.368028e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1668 | Q67 | What is the top-associated SNP of the gene CNN2 in Whole Blood eQTL GTEx omic data for AD and is it functionally significant? | The top-associated SNP for CNN2 in Whole Blood eQTL GTEx omic data for AD is rs3087680, which has a multi-SNP SMR p-value of 1.39e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CNN2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1652807', 'topRSID': 'rs3087680', 'Disease': 'AD', 'Gene': 'CNN2', 'p_SMR_multi': 1.394849e-06, 'p_HEIDI': 0.00650461, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL GTEx', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Di... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.454 | Q67 | What is the top-associated SNP of the gene XYLT1 in Whole Brain meta-analysis mQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene XYLT1 in Whole Brain meta-analysis mQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "XYLT1" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_205002', 'topRSID': 'rs7192588', 'Disease': 'ALS', 'Gene': 'XYLT1', 'p_SMR_multi': 0.0539105, 'p_HEIDI': 0.3222458, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_2... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.723 | Q67 | What is the top-associated SNP of the gene RP11-259G18.1 in Putamen Basal Ganglia eQTL omic data for PD and is it functionally significant? | The top-associated SNP for RP11-259G18.1 in Putamen Basal Ganglia eQTL omic data for PD is rs757055, which has a multi-SNP SMR p-value of 7.62e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%putamen basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1594927', 'topRSID': 'rs757055', 'Disease': 'PD', 'Gene': 'RP11-259G18.1', 'p_SMR_multi': 7.618063e-09, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Putamen Basal Ganglia', 'Omic_type': 'Putamen Basal Ganglia eQTL', 'func_sig': 'association meets significance threshold but shows signs of... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1261 | Q67 | What is the top-associated SNP of the gene STH in Cortex eQTL metaBrain omic data for PD and is it functionally significant? | The top-associated SNP for STH in Cortex eQTL metaBrain omic data for PD is rs11079718, which has a multi-SNP SMR p-value of 9.43e-08 and a HEIDI of 0.72, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "STH" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1147255', 'topRSID': 'rs11079718', 'Disease': 'PD', 'Gene': 'STH', 'p_SMR_multi': 9.425613e-08, 'p_HEIDI': 0.7186979, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1598 | Q67 | What is the top-associated SNP of the gene EPHA1-AS1 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for EPHA1-AS1 in Whole Blood mQTL omic data for AD is rs1404650, which has a multi-SNP SMR p-value of 2.38e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "EPHA1-AS1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_587067', 'topRSID': 'rs75045569', 'Disease': 'AD', 'Gene': 'EPHA1-AS1', 'p_SMR_multi': 6.942181e-09, 'p_HEIDI': 0.1635299, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_587068', 'to... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1 | Q67 | What is the top-associated SNP of the gene RP11-333E1.1 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for RP11-333E1.1 in Whole Blood mQTL omic data for AD is rs112918260, which has a multi-SNP SMR p-value of 4.79e-08 and a HEIDI of 0.27, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-333E1.1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_589057', 'topRSID': 'rs112918260', 'Disease': 'AD', 'Gene': 'RP11-333E1.1', 'p_SMR_multi': 4.791144e-08, 'p_HEIDI': 0.2742732, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_589056',... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1377 | Q67 | What is the top-associated SNP of the gene C9orf72 in Whole Brain eQTL omic data for ALS and is it functionally significant? | The top-associated SNP for C9orf72 in Whole Brain eQTL omic data for ALS is rs774358, which has a multi-SNP SMR p-value of 4.22e-14 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "C9orf72" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1615729', 'topRSID': 'rs774358', 'Disease': 'ALS', 'Gene': 'C9orf72', 'p_SMR_multi': 4.220426e-14, 'p_HEIDI': 2.192468e-08, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Di... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1110 | Q67 | What is the top-associated SNP of the gene LRRC37A2 in Cerebellum eQTL omic data for AD and is it functionally significant? | The top-associated SNP for LRRC37A2 in Cerebellum eQTL omic data for AD is rs17564020, which has a multi-SNP SMR p-value of 1.64e-06 and a HEIDI of 0.86, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_2660', 'topRSID': 'rs2532233', 'Disease': 'AD', 'Gene': 'LRRC37A2', 'p_SMR_multi': 8.412029e-07, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequilibr... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1117 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for MAPT in Whole Blood mQTL omic data for AD is rs2532233, which has a multi-SNP SMR p-value of 4.34e-07 and a HEIDI of 0.5, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_591203', 'topRSID': 'rs17689882', 'Disease': 'AD', 'Gene': 'MAPT', 'p_SMR_multi': 2.532079e-07, 'p_HEIDI': 0.02723276, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_591210', 'topRSI... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1591 | Q67 | What is the top-associated SNP of the gene GPC6 in Whole Blood mQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene GPC6 in Whole Blood mQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GPC6" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_613005', 'topRSID': 'rs9561295', 'Disease': 'AD', 'Gene': 'GPC6', 'p_SMR_multi': 0.1263157, 'p_HEIDI': 0.3739227, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_613004', 'topRSID... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.85 | Q67 | What is the top-associated SNP of the gene ELFN1 in Whole Blood mQTL omic data for PSP and is it functionally significant? | There are no SNPs within the gene ELFN1 in Whole Blood mQTL omic data that are significantly associated with PSP, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ELFN1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1046683', 'topRSID': 'rs6950626', 'Disease': 'PSP', 'Gene': 'ELFN1', 'p_SMR_multi': 0.1348274, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_1046677', 'topRS... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1294 | Q67 | What is the top-associated SNP of the gene RP11-259G18.2 in Putamen Basal Ganglia eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-259G18.2 in Putamen Basal Ganglia eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 1.56e-15 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.2" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%putamen basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1596823', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'RP11-259G18.2', 'p_SMR_multi': 1.562688e-15, 'p_HEIDI': 2.003077e-15, 'Omic_tissue': 'Putamen Basal Ganglia', 'Omic_type': 'Putamen Basal Ganglia eQTL', 'func_sig': 'association meets significance threshold but shows s... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.683 | Q67 | What is the top-associated SNP of the gene C9orf72 in Prefrontal Cortex eQTL omic data for ALS and is it functionally significant? | The top-associated SNP for C9orf72 in Prefrontal Cortex eQTL omic data for ALS is rs2492816, which has a multi-SNP SMR p-value of 1.79e-15 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "C9orf72" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%prefrontal cortex eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1209518', 'topRSID': 'rs2492816', 'Disease': 'ALS', 'Gene': 'C9orf72', 'p_SMR_multi': 1.789029e-15, 'p_HEIDI': 4.866677e-14, 'Omic_tissue': 'Prefrontal Cortex', 'Omic_type': 'Prefrontal Cortex eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1677 | Q67 | What is the top-associated SNP of the gene PVRIG in Cortex eQTL GTEx omic data for AD and is it functionally significant? | The top-associated SNP for PVRIG in Cortex eQTL GTEx omic data for AD is rs7811662, which has a multi-SNP SMR p-value of 4.11e-07 and a HEIDI of 0.02, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PVRIG" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cortex eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1245519', 'topRSID': 'rs7811662', 'Disease': 'AD', 'Gene': 'PVRIG', 'p_SMR_multi': 4.107899e-07, 'p_HEIDI': 0.02194134, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL GTEx', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1055 | Q67 | What is the top-associated SNP of the gene LRRC37A4P in Skeletal Muscle eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for LRRC37A4P in Skeletal Muscle eQTL omic data for PSP is rs12373139, which has a multi-SNP SMR p-value of 8.37e-27 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A4P" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1375923', 'topRSID': 'rs12373139', 'Disease': 'PSP', 'Gene': 'LRRC37A4P', 'p_SMR_multi': 8.369824000000001e-27, 'p_HEIDI': 3.313104e-22, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'association meets significance threshold but shows signs o... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.777 | Q67 | What is the top-associated SNP of the gene KLHL7-AS1 in Prefrontal Cortex eQTL omic data for PD and is it functionally significant? | The top-associated SNP for KLHL7-AS1 in Prefrontal Cortex eQTL omic data for PD is rs10241208, which has a multi-SNP SMR p-value of 2.23e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KLHL7-AS1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%prefrontal cortex eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1237813', 'topRSID': 'rs10241208', 'Disease': 'PD', 'Gene': 'KLHL7-AS1', 'p_SMR_multi': 2.234187e-08, 'p_HEIDI': 0.0004724868, 'Omic_tissue': 'Prefrontal Cortex', 'Omic_type': 'Prefrontal Cortex eQTL', 'func_sig': 'association meets significance threshold but shows signs of link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1289 | Q67 | What is the top-associated SNP of the gene TMEM175 in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for TMEM175 in Whole Blood mQTL omic data for PD is rs6813110, which has a multi-SNP SMR p-value of 4.65e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TMEM175" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_996283', 'topRSID': 'rs6813110', 'Disease': 'PD', 'Gene': 'TMEM175', 'p_SMR_multi': 2.618289e-11, 'p_HEIDI': 0.0001221027, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1946 | Q67 | What is the top-associated SNP of the gene KLHL7-AS1 in Caudate Basal Ganglia eQTL omic data for PD and is it functionally significant? | The top-associated SNP for KLHL7-AS1 in Caudate Basal Ganglia eQTL omic data for PD is rs6953728, which has a multi-SNP SMR p-value of 3.29e-07 and a HEIDI of 0.02, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KLHL7-AS1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%caudate basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1279898', 'topRSID': 'rs6953728', 'Disease': 'PD', 'Gene': 'KLHL7-AS1', 'p_SMR_multi': 3.291241e-07, 'p_HEIDI': 0.02070421, 'Omic_tissue': 'Caudate Basal Ganglia', 'Omic_type': 'Caudate Basal Ganglia eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1581 | Q67 | What is the top-associated SNP of the gene LRRC37A2 in Cortex eQTL GTEx omic data for PSP and is it functionally significant? | The top-associated SNP for LRRC37A2 in Cortex eQTL GTEx omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 1.15e-19 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A2" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%cortex eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1264989', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'LRRC37A2', 'p_SMR_multi': 1.153006e-19, 'p_HEIDI': 2.095334e-21, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL GTEx', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1490 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for MAPT in Whole Blood mQTL omic data for PD is rs112746008, which has a multi-SNP SMR p-value of 4.72e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_948891', 'topRSID': 'rs62063271', 'Disease': 'PD', 'Gene': 'MAPT', 'p_SMR_multi': 6.382411e-15, 'p_HEIDI': 2.368028e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.410 | Q67 | What is the top-associated SNP of the gene ARL17A in Cerebellum eQTL omic data for PD and is it functionally significant? | The top-associated SNP for ARL17A in Cerebellum eQTL omic data for PD is rs55974014, which has a multi-SNP SMR p-value of 2.94e-12 and a HEIDI of 0.21, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17A" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_19651', 'topRSID': 'rs4471723', 'Disease': 'PD', 'Gene': 'ARL17A', 'p_SMR_multi': 1.337634e-13, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequilibri... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1728 | Q67 | What is the top-associated SNP of the gene RP11-469N6.1 in Tibial Nerve eQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene RP11-469N6.1 in Tibial Nerve eQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-469N6.1" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1299112', 'topRSID': 'rs10791390', 'Disease': 'ALS', 'Gene': 'RP11-469N6.1', 'p_SMR_multi': 0.1338846, 'p_HEIDI': 0.3144104, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1298 | Q67 | What is the top-associated SNP of the gene GCLC in Whole Blood mQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene GCLC in Whole Blood mQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GCLC" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_623094', 'topRSID': 'rs510088', 'Disease': 'AD', 'Gene': 'GCLC', 'p_SMR_multi': 0.3011463, 'p_HEIDI': 0.8593503, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1665 | Q67 | What is the top-associated SNP of the gene DND1P1 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for DND1P1 in Whole Brain meta-analysis mQTL omic data for PD is rs1724390, which has a multi-SNP SMR p-value of 3.08e-13 and a HEIDI of 0.04, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DND1P1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491080', 'topRSID': 'rs1724390', 'Disease': 'PD', 'Gene': 'DND1P1', 'p_SMR_multi': 3.078724e-13, 'p_HEIDI': 0.03753698, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_4... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.107 | Q67 | What is the top-associated SNP of the gene LRRC37A in Frontal Cortex BA9 eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for LRRC37A in Frontal Cortex BA9 eQTL omic data for PSP is rs7225002, which has a multi-SNP SMR p-value of 8.26e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%frontal cortex ba9 eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1170877', 'topRSID': 'rs7225002', 'Disease': 'PSP', 'Gene': 'LRRC37A', 'p_SMR_multi': 8.264816e-11, 'p_HEIDI': 1.034575e-09, 'Omic_tissue': 'Frontal Cortex', 'Omic_type': 'Frontal Cortex BA9 eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.695 | Q67 | What is the top-associated SNP of the gene BIN1 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for BIN1 in Whole Blood mQTL omic data for AD is rs11682128, which has a multi-SNP SMR p-value of 2.10e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "BIN1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_631119', 'topRSID': 'rs58402148', 'Disease': 'AD', 'Gene': 'BIN1', 'p_SMR_multi': 2.405281e-31, 'p_HEIDI': 3.999879e-37, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1305 | Q67 | What is the top-associated SNP of the gene ARHGAP27 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for ARHGAP27 in Whole Brain meta-analysis mQTL omic data for PD is rs62064641, which has a multi-SNP SMR p-value of 3.98e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARHGAP27" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491057', 'topRSID': 'rs62065376', 'Disease': 'PD', 'Gene': 'ARHGAP27', 'p_SMR_multi': 1.134698e-11, 'p_HEIDI': 0.3072466, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.833 | Q67 | What is the top-associated SNP of the gene PARP14 in Whole Blood mQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene PARP14 in Whole Blood mQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PARP14" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_679908', 'topRSID': 'rs13066729', 'Disease': 'ALS', 'Gene': 'PARP14', 'p_SMR_multi': 0.05157509, 'p_HEIDI': 0.06921463, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_679910', 't... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.64 | Q67 | What is the top-associated SNP of the gene RRM1 in Cerebellar Hemisphere eQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene RRM1 in Cerebellar Hemisphere eQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RRM1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cerebellar hemisphere eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1173491', 'topRSID': 'rs12806698', 'Disease': 'AD', 'Gene': 'RRM1', 'p_SMR_multi': 0.6794965, 'p_HEIDI': 0.8063952, 'Omic_tissue': 'Cerebellar Hemisphere', 'Omic_type': 'Cerebellar Hemisphere eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.859 | Q67 | What is the top-associated SNP of the gene MARK4 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for MARK4 in Whole Blood eQTL eQTLgen omic data for AD is rs344806, which has a multi-SNP SMR p-value of 4.89e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MARK4" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1503916', 'topRSID': 'rs344806', 'Disease': 'AD', 'Gene': 'MARK4', 'p_SMR_multi': 4.892338e-07, 'p_HEIDI': 1.03524e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1355 | Q67 | What is the top-associated SNP of the gene APP in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for APP in Whole Blood eQTL eQTLgen omic data for AD is rs2830076, which has a multi-SNP SMR p-value of 3.19e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "APP" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1504767', 'topRSID': 'rs2830076', 'Disease': 'AD', 'Gene': 'APP', 'p_SMR_multi': 3.194649e-07, 'p_HEIDI': 5.286428e-05, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.226 | Q67 | What is the top-associated SNP of the gene IGSF9B in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for IGSF9B in Whole Brain meta-analysis mQTL omic data for PD is rs11223627, which has a multi-SNP SMR p-value of 5.36e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "IGSF9B" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_470339', 'topRSID': 'rs1793680', 'Disease': 'PD', 'Gene': 'IGSF9B', 'p_SMR_multi': 2.071103e-10, 'p_HEIDI': 0.006061729, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.148 | Q67 | What is the top-associated SNP of the gene RP11-433J8.1 in Nucleus Accumbens Basal Ganglia omic data for LBD and is it functionally significant? | There are no SNPs within the gene RP11-433J8.1 in Nucleus Accumbens Basal Ganglia omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-433J8.1" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%nucleus accumbens basal ganglia%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1726463', 'topRSID': 'rs75564413', 'Disease': 'LBD', 'Gene': 'RP11-433J8.1', 'p_SMR_multi': 0.1416904, 'p_HEIDI': 0.409238, 'Omic_tissue': 'Nucleus Accumbens Basal', 'Omic_type': 'Nucleus Accumbens Basal Ganglia', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1097 | Q67 | What is the top-associated SNP of the gene SPPL2C in Cortex eQTL metaBrain omic data for PD and is it functionally significant? | The top-associated SNP for SPPL2C in Cortex eQTL metaBrain omic data for PD is rs55980621, which has a multi-SNP SMR p-value of 1.55e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SPPL2C" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1147254', 'topRSID': 'rs55980621', 'Disease': 'PD', 'Gene': 'SPPL2C', 'p_SMR_multi': 1.548639e-09, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequi... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.379 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for MAPT in Whole Brain meta-analysis mQTL omic data for PD is rs41543317, which has a multi-SNP SMR p-value of 7.03e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491114', 'topRSID': 'rs17652121', 'Disease': 'PD', 'Gene': 'MAPT', 'p_SMR_multi': 4.729064e-14, 'p_HEIDI': 0.04416005, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_49... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1422 | Q67 | What is the top-associated SNP of the gene RP11-104H15.7 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene RP11-104H15.7 in Whole Brain meta-analysis mQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-104H15.7" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_113292', 'topRSID': 'rs4796305', 'Disease': 'AD', 'Gene': 'RP11-104H15.7', 'p_SMR_multi': 0.0438408, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_t... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1152 | Q67 | What is the top-associated SNP of the gene DND1P1 in Putamen Basal Ganglia eQTL omic data for PD and is it functionally significant? | The top-associated SNP for DND1P1 in Putamen Basal Ganglia eQTL omic data for PD is rs55974014, which has a multi-SNP SMR p-value of 1.09e-11 and a HEIDI of 0.43, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DND1P1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%putamen basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1594920', 'topRSID': 'rs55974014', 'Disease': 'PD', 'Gene': 'DND1P1', 'p_SMR_multi': 1.093413e-11, 'p_HEIDI': 0.4344016, 'Omic_tissue': 'Putamen Basal Ganglia', 'Omic_type': 'Putamen Basal Ganglia eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1828 | Q67 | What is the top-associated SNP of the gene LRRC37A2 in Substantia nigra eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for LRRC37A2 in Substantia nigra eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 1.03e-13 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A2" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%substantia nigra eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1452486', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'LRRC37A2', 'p_SMR_multi': 1.031055e-13, 'p_HEIDI': 2.258729e-06, 'Omic_tissue': 'Substantia nigra', 'Omic_type': 'Substantia nigra eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1496 | Q67 | What is the top-associated SNP of the gene NFATC2 in Whole Brain meta-analysis mQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene NFATC2 in Whole Brain meta-analysis mQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NFATC2" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_312846', 'topRSID': 'rs2235856', 'Disease': 'FTD', 'Gene': 'NFATC2', 'p_SMR_multi': 0.1844217, 'p_HEIDI': 0.9251102, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1602 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Brain meta-analysis mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for MAPT in Whole Brain meta-analysis mQTL omic data for PSP is rs8070723, which has a multi-SNP SMR p-value of 6.08e-15 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_560864', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'MAPT', 'p_SMR_multi': 2.100115e-44, 'p_HEIDI': 0.01425494, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_56... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1759 | Q67 | What is the top-associated SNP of the gene LRRC37A2 in Whole Brain eQTL omic data for AD and is it functionally significant? | The top-associated SNP for LRRC37A2 in Whole Brain eQTL omic data for AD is rs55825513, which has a multi-SNP SMR p-value of 4.35e-08 and a HEIDI of 0.03, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1610873', 'topRSID': 'rs55825513', 'Disease': 'AD', 'Gene': 'LRRC37A2', 'p_SMR_multi': 4.35167e-08, 'p_HEIDI': 0.02762345, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.10 | Q67 | What is the top-associated SNP of the gene ALDH1A2 in Whole Blood mQTL omic data for PSP and is it functionally significant? | There are no SNPs within the gene ALDH1A2 in Whole Blood mQTL omic data that are significantly associated with PSP, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ALDH1A2" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1044815', 'topRSID': 'rs7167150', 'Disease': 'PSP', 'Gene': 'ALDH1A2', 'p_SMR_multi': 0.1315463, 'p_HEIDI': 0.7096179, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_1044817', 't... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.455 | Q67 | What is the top-associated SNP of the gene RN7SL199P in Prefrontal Cortex eQTL omic data for AD and is it functionally significant? | The top-associated SNP for RN7SL199P in Prefrontal Cortex eQTL omic data for AD is rs199447, which has a multi-SNP SMR p-value of 3.95e-07 and a HEIDI of 0.01, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RN7SL199P" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%prefrontal cortex eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1203021', 'topRSID': 'rs199447', 'Disease': 'AD', 'Gene': 'RN7SL199P', 'p_SMR_multi': 3.952554e-07, 'p_HEIDI': 0.01121612, 'Omic_tissue': 'Prefrontal Cortex', 'Omic_type': 'Prefrontal Cortex eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.715 | Q67 | What is the top-associated SNP of the gene TNNT2 in Whole Brain eQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene TNNT2 in Whole Brain eQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TNNT2" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1627505', 'topRSID': 'rs4606345', 'Disease': 'LBD', 'Gene': 'TNNT2', 'p_SMR_multi': 0.3862374, 'p_HEIDI': 0.3222886, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.258 | Q67 | What is the top-associated SNP of the gene RP11-707O23.5 in Cerebellum eQTL omic data for PD and is it functionally significant? | The top-associated SNP for RP11-707O23.5 in Cerebellum eQTL omic data for PD is rs55974014, which has a multi-SNP SMR p-value of 1.11e-12 and a HEIDI of 0.9, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-707O23.5" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1710346', 'topRSID': 'rs55974014', 'Disease': 'PD', 'Gene': 'RP11-707O23.5', 'p_SMR_multi': 1.110527e-12, 'p_HEIDI': 0.9006067, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.889 | Q67 | What is the top-associated SNP of the gene HDDC2 in Cortex eQTL metaBrain omic data for FTD and is it functionally significant? | There are no SNPs within the gene HDDC2 in Cortex eQTL metaBrain omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "HDDC2" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1122768', 'topRSID': 'rs3734642', 'Disease': 'FTD', 'Gene': 'HDDC2', 'p_SMR_multi': 0.1270935, 'p_HEIDI': 0.283897, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.395 | Q67 | What is the top-associated SNP of the gene RP11-707O23.5 in Skeletal Muscle eQTL omic data for PD and is it functionally significant? | The top-associated SNP for RP11-707O23.5 in Skeletal Muscle eQTL omic data for PD is rs55974014, which has a multi-SNP SMR p-value of 1.12e-15 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-707O23.5" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1370541', 'topRSID': 'rs55974014', 'Disease': 'PD', 'Gene': 'RP11-707O23.5', 'p_SMR_multi': 1.118686e-15, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.916 | Q67 | What is the top-associated SNP of the gene LACTB in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for LACTB in Whole Blood eQTL eQTLgen omic data for AD is rs2729779, which has a multi-SNP SMR p-value of 7.14e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LACTB" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1500801', 'topRSID': 'rs2729779', 'Disease': 'AD', 'Gene': 'LACTB', 'p_SMR_multi': 7.143396e-08, 'p_HEIDI': 1.512549e-08, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.932 | Q67 | What is the top-associated SNP of the gene MVK in Whole Brain meta-analysis mQTL omic data for PSP and is it functionally significant? | There are no SNPs within the gene MVK in Whole Brain meta-analysis mQTL omic data that are significantly associated with PSP, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MVK" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_548634', 'topRSID': 'rs11066813', 'Disease': 'PSP', 'Gene': 'MVK', 'p_SMR_multi': 0.6713278, 'p_HEIDI': 0.461883, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_548... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1704 | Q67 | What is the top-associated SNP of the gene STAG3 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for STAG3 in Whole Blood eQTL eQTLgen omic data for AD is rs7786505, which has a multi-SNP SMR p-value of 6.20e-10 and a HEIDI of 0.03, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "STAG3" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1495800', 'topRSID': 'rs7786505', 'Disease': 'AD', 'Gene': 'STAG3', 'p_SMR_multi': 6.195954e-10, 'p_HEIDI': 0.02897947, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1231 | Q67 | What is the top-associated SNP of the gene CBLC in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for CBLC in Whole Blood mQTL omic data for AD is rs2965118, which has a multi-SNP SMR p-value of 1.68e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CBLC" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_637417', 'topRSID': 'rs2965118', 'Disease': 'AD', 'Gene': 'CBLC', 'p_SMR_multi': 1.680736e-08, 'p_HEIDI': 0.003526909, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequi... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.466 | Q67 | What is the top-associated SNP of the gene KANSL1-AS1 in Skeletal Muscle eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for KANSL1-AS1 in Skeletal Muscle eQTL omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 9.89e-37 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1-AS1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1375930', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'KANSL1-AS1', 'p_SMR_multi': 9.889983e-37, 'p_HEIDI': 1.344879e-13, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1967 | Q67 | What is the top-associated SNP of the gene PVRL2 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for PVRL2 in Whole Brain meta-analysis mQTL omic data for AD is rs1871046, which has a multi-SNP SMR p-value of 8.28e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PVRL2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_122461', 'topRSID': 'rs1871046', 'Disease': 'AD', 'Gene': 'PVRL2', 'p_SMR_multi': 8.280413e-07, 'p_HEIDI': 5.964197e-10, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1178 | Q67 | What is the top-associated SNP of the gene PM20D1 in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for PM20D1 in Whole Blood mQTL omic data for PD is rs823080, which has a multi-SNP SMR p-value of 9.25e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PM20D1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_944692', 'topRSID': 'rs823080', 'Disease': 'PD', 'Gene': 'PM20D1', 'p_SMR_multi': 7.078994e-07, 'p_HEIDI': 1.577211e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.967 | Q67 | What is the top-associated SNP of the gene RP11-120K18.3 in Whole Blood eQTL eQTLgen omic data for PD and is it functionally significant? | The top-associated SNP for RP11-120K18.3 in Whole Blood eQTL eQTLgen omic data for PD is rs11150614, which has a multi-SNP SMR p-value of 3.67e-07 and a HEIDI of 0.13, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-120K18.3" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1563821', 'topRSID': 'rs11150614', 'Disease': 'PD', 'Gene': 'RP11-120K18.3', 'p_SMR_multi': 3.669227e-07, 'p_HEIDI': 0.1276231, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.507 | Q67 | What is the top-associated SNP of the gene ARL17A in Cortex eQTL metaBrain omic data for PSP and is it functionally significant? | The top-associated SNP for ARL17A in Cortex eQTL metaBrain omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 9.73e-46 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17A" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1154401', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'ARL17A', 'p_SMR_multi': 9.72687e-46, 'p_HEIDI': 5.601894e-32, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.746 | Q67 | What is the top-associated SNP of the gene TMEM106B in Whole Blood mQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene TMEM106B in Whole Blood mQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TMEM106B" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_725730', 'topRSID': 'rs3807865', 'Disease': 'ALS', 'Gene': 'TMEM106B', 'p_SMR_multi': 0.08967469, 'p_HEIDI': 0.02451183, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_725731', '... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1851 | Q67 | What is the top-associated SNP of the gene BIN1 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for BIN1 in Whole Brain meta-analysis mQTL omic data for AD is rs10929008, which has a multi-SNP SMR p-value of 1.35e-14 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "BIN1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_46339', 'topRSID': 'rs730471', 'Disease': 'AD', 'Gene': 'BIN1', 'p_SMR_multi': 2.124617e-16, 'p_HEIDI': 3.050073e-22, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Li... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.875 | Q67 | What is the top-associated SNP of the gene SLC24A4 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for SLC24A4 in Whole Blood mQTL omic data for AD is rs61977309, which has a multi-SNP SMR p-value of 3.35e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SLC24A4" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_595679', 'topRSID': 'rs61977309', 'Disease': 'AD', 'Gene': 'SLC24A4', 'p_SMR_multi': 3.351841e-09, 'p_HEIDI': 0.001900887, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.738 | Q67 | What is the top-associated SNP of the gene PLEKHM1 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PD and is it functionally significant? | The top-associated SNP for PLEKHM1 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PD is rs10451283, which has a multi-SNP SMR p-value of 3.22e-13 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PLEKHM1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 10... | [{'UUID': 'NDD_SMR_genes_all_update_text_1435913', 'topRSID': 'rs10451283', 'Disease': 'PD', 'Gene': 'PLEKHM1', 'p_SMR_multi': 3.220666e-13, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance threshol... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.545 | Q67 | What is the top-associated SNP of the gene RP11-137H2.4 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for RP11-137H2.4 in Whole Blood eQTL eQTLgen omic data for AD is rs11185932, which has a multi-SNP SMR p-value of 2.57e-09 and a HEIDI of 0.1, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-137H2.4" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1497630', 'topRSID': 'rs11185932', 'Disease': 'AD', 'Gene': 'RP11-137H2.4', 'p_SMR_multi': 2.56544e-09, 'p_HEIDI': 0.1026472, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1211 | Q67 | What is the top-associated SNP of the gene ARL17A in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for ARL17A in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PSP is rs12373139, which has a multi-SNP SMR p-value of 3.40e-32 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17A" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 10... | [{'UUID': 'NDD_SMR_genes_all_update_text_1444276', 'topRSID': 'rs12373139', 'Disease': 'PSP', 'Gene': 'ARL17A', 'p_SMR_multi': 3.401272e-32, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance threshol... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.704 | Q67 | What is the top-associated SNP of the gene SNCA in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for SNCA in Whole Brain meta-analysis mQTL omic data for PD is rs6817026, which has a multi-SNP SMR p-value of 1.92e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SNCA" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_432414', 'topRSID': 'rs3756059', 'Disease': 'PD', 'Gene': 'SNCA', 'p_SMR_multi': 2.653319e-12, 'p_HEIDI': 9.429443e-19, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1394 | Q67 | What is the top-associated SNP of the gene TSC22D4 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for TSC22D4 in Whole Blood mQTL omic data for AD is rs67163493, which has a multi-SNP SMR p-value of 5.75e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TSC22D4" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_586004', 'topRSID': 'rs67163493', 'Disease': 'AD', 'Gene': 'TSC22D4', 'p_SMR_multi': 5.747145e-11, 'p_HEIDI': 0.0006834187, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Di... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1783 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for MAPT in Whole Blood mQTL omic data for PD is rs538628, which has a multi-SNP SMR p-value of 2.38e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_948891', 'topRSID': 'rs62063271', 'Disease': 'PD', 'Gene': 'MAPT', 'p_SMR_multi': 6.382411e-15, 'p_HEIDI': 2.368028e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1155 | Q67 | What is the top-associated SNP of the gene APOC4 in Liver eQTL omic data for AD and is it functionally significant? | The top-associated SNP for APOC4 in Liver eQTL omic data for AD is rs73045691, which has a multi-SNP SMR p-value of 3.17e-11 and a HEIDI of 0.47, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "APOC4" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%liver eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1466879', 'topRSID': 'rs73045691', 'Disease': 'AD', 'Gene': 'APOC4', 'p_SMR_multi': 3.171686e-11, 'p_HEIDI': 0.4688313, 'Omic_tissue': 'Liver', 'Omic_type': 'Liver eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1040 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for MAPT in Whole Blood mQTL omic data for AD is rs111751251, which has a multi-SNP SMR p-value of 6.76e-07 and a HEIDI of 0.05, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_591203', 'topRSID': 'rs17689882', 'Disease': 'AD', 'Gene': 'MAPT', 'p_SMR_multi': 2.532079e-07, 'p_HEIDI': 0.02723276, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_591210', 'topRSI... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.378 | Q67 | What is the top-associated SNP of the gene TMEM106B in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for TMEM106B in Whole Blood mQTL omic data for AD is rs3807865, which has a multi-SNP SMR p-value of 9.81e-07 and a HEIDI of 0.36, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TMEM106B" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_583798', 'topRSID': 'rs3807865', 'Disease': 'AD', 'Gene': 'TMEM106B', 'p_SMR_multi': 9.805484e-07, 'p_HEIDI': 0.3619829, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_583799', 'topR... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.674 | Q67 | What is the top-associated SNP of the gene IDUA in Whole Blood eQTL GTEx omic data for PD and is it functionally significant? | The top-associated SNP for IDUA in Whole Blood eQTL GTEx omic data for PD is rs11248061, which has a multi-SNP SMR p-value of 4.08e-07 and a HEIDI of 0.02, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "IDUA" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1675612', 'topRSID': 'rs11248061', 'Disease': 'PD', 'Gene': 'IDUA', 'p_SMR_multi': 4.08187e-07, 'p_HEIDI': 0.02435755, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL GTEx', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1527 | Q67 | What is the top-associated SNP of the gene KANSL1 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for KANSL1 in Whole Brain meta-analysis mQTL omic data for PD is rs551913443, which has a multi-SNP SMR p-value of 8.30e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491139', 'topRSID': 'rs12150087', 'Disease': 'PD', 'Gene': 'KANSL1', 'p_SMR_multi': 8.107128999999999e-20, 'p_HEIDI': 0.009069932, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs o... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.362 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for MAPT in Whole Blood mQTL omic data for AD is rs111541901, which has a multi-SNP SMR p-value of 2.69e-07 and a HEIDI of 0.07, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_591203', 'topRSID': 'rs17689882', 'Disease': 'AD', 'Gene': 'MAPT', 'p_SMR_multi': 2.532079e-07, 'p_HEIDI': 0.02723276, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_591210', 'topRSI... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.976 | Q67 | What is the top-associated SNP of the gene KANSL1 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for KANSL1 in Whole Brain meta-analysis mQTL omic data for PD is rs2696610, which has a multi-SNP SMR p-value of 2.04e-06 and a HEIDI of 0.6, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491139', 'topRSID': 'rs12150087', 'Disease': 'PD', 'Gene': 'KANSL1', 'p_SMR_multi': 8.107128999999999e-20, 'p_HEIDI': 0.009069932, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs o... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.790 | Q67 | What is the top-associated SNP of the gene ARHGAP27 in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for ARHGAP27 in Whole Blood mQTL omic data for PD is rs112454267, which has a multi-SNP SMR p-value of 1.61e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARHGAP27" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_948846', 'topRSID': 'rs35489312', 'Disease': 'PD', 'Gene': 'ARHGAP27', 'p_SMR_multi': 3.386602e-15, 'p_HEIDI': 0.001263654, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Di... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.742 | Q67 | What is the top-associated SNP of the gene RP11-259G18.1 in Cerebellar Hemisphere eQTL omic data for PD and is it functionally significant? | The top-associated SNP for RP11-259G18.1 in Cerebellar Hemisphere eQTL omic data for PD is rs4564621, which has a multi-SNP SMR p-value of 3.44e-12 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cerebellar hemisphere eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1191175', 'topRSID': 'rs4564621', 'Disease': 'PD', 'Gene': 'RP11-259G18.1', 'p_SMR_multi': 3.444404e-12, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Cerebellar Hemisphere', 'Omic_type': 'Cerebellar Hemisphere eQTL', 'func_sig': 'association meets significance threshold but shows signs o... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1044 | Q67 | What is the top-associated SNP of the gene STK39 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for STK39 in Whole Brain meta-analysis mQTL omic data for PD is rs13016703, which has a multi-SNP SMR p-value of 2.99e-07 and a HEIDI of 0.14, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "STK39" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_422838', 'topRSID': 'rs2390669', 'Disease': 'PD', 'Gene': 'STK39', 'p_SMR_multi': 1.174594e-07, 'p_HEIDI': 0.4649286, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_422... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.979 | Q67 | What is the top-associated SNP of the gene BST1 in Whole Blood eQTL eQTLgen omic data for PD and is it functionally significant? | The top-associated SNP for BST1 in Whole Blood eQTL eQTLgen omic data for PD is rs34559912, which has a multi-SNP SMR p-value of 7.48e-11 and a HEIDI of 0.16, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "BST1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1555730', 'topRSID': 'rs34559912', 'Disease': 'PD', 'Gene': 'BST1', 'p_SMR_multi': 7.480451e-11, 'p_HEIDI': 0.1584458, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
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