uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
values | bio_category stringclasses 14
values |
|---|---|---|---|---|---|---|---|---|
Q1.1312 | Q1 | Is RPTOR a druggable gene? | There are currently no approved drugs targeting RPTOR, but there is 1 drug in a clinical trial indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%RPTOR %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_2816', 'drugName': 'Indoximod', 'drugIsApproved': False, 'newLinkedTargets_string': 'MTOR (ENSG00000198793), RPTOR (ENSG00000141564), MLST8 (ENSG00000167965)', 'maxClinicalTrialPhase': 2}] | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1330 | Q1 | Is SCN10A a druggable gene? | There are currently 80 approved drugs which target SCN10A, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%SCN10A %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_3875', 'drugName': 'Dronedarone Hydrochloride', 'drugIsApproved': True, 'newLinkedTargets_string': 'CACNA1C (ENSG00000151067), CACNA1S (ENSG00000081248), CACNA1D (ENSG00000157388), CACNA1F (ENSG00000102001), HCN4 (ENSG00000138622), SCN1A (ENSG00000144285), SCN5A (ENSG00000183873), SCN4A (E... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.214 | Q1 | Is CD4 a druggable gene? | There is 1 drug, Ibalizumab, that targets CD4, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%CD4 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1583', 'drugName': 'Ibalizumab', 'drugIsApproved': True, 'newLinkedTargets_string': 'CD4 (ENSG00000010610)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_4573', 'drugName': 'Zanolimumab', 'drugIsApproved': False, 'newLinkedTargets_string': 'CD4 (ENSG00000010610)', 'maxClinical... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.890 | Q1 | Is MLNR a druggable gene? | There are currently no approved drugs targeting MLNR, but there are 4 drugs in clinical trials indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%MLNR %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_4697', 'drugName': 'Camicinal', 'drugIsApproved': False, 'newLinkedTargets_string': 'MLNR (ENSG00000102539)', 'maxClinicalTrialPhase': 3}, {'UUID': 'DrugGeneTargets_v2_232', 'drugName': 'Mitemcinal', 'drugIsApproved': False, 'newLinkedTargets_string': 'MLNR (ENSG00000102539)', 'maxClinical... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.81 | Q1 | Is ATP1A2 a druggable gene? | There are currently 5 approved drugs which target ATP1A2, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%ATP1A2 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_2499', 'drugName': 'Digoxin', 'drugIsApproved': True, 'newLinkedTargets_string': 'ATP1A1 (ENSG00000163399), ATP1B2 (ENSG00000129244), ATP1B1 (ENSG00000143153), ATP1A2 (ENSG00000018625), ATP1B3 (ENSG00000069849), ATP1A3 (ENSG00000105409), ATP1A4 (ENSG00000132681), FXYD2 (ENSG00000137731)', ... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.150 | Q1 | Is CACNA1I a druggable gene? | There are currently 16 approved drugs which target CACNA1I, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%CACNA1I %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_4418', 'drugName': 'Trimethadione', 'drugIsApproved': True, 'newLinkedTargets_string': 'CACNA1H (ENSG00000196557), CACNA1G (ENSG00000006283), CACNA1I (ENSG00000100346)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_4085', 'drugName': 'Methsuximide', 'drugIsApproved': True, 'ne... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.819 | Q1 | Is LGALS3 a druggable gene? | There are currently no approved drugs targeting LGALS3, but there are 3 drugs in clinical trials indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%LGALS3 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_6390', 'drugName': 'Belapectin', 'drugIsApproved': False, 'newLinkedTargets_string': 'LGALS3 (ENSG00000131981)', 'maxClinicalTrialPhase': 2}, {'UUID': 'DrugGeneTargets_v2_3707', 'drugName': 'Olitigaltin', 'drugIsApproved': False, 'newLinkedTargets_string': 'LGALS3 (ENSG00000131981)', 'maxC... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1208 | Q1 | Is RAMP1 a druggable gene? | There are currently 2 approved drugs which target RAMP1, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%RAMP1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_2396', 'drugName': 'Pramlintide Acetate', 'drugIsApproved': True, 'newLinkedTargets_string': 'CALCR (ENSG00000004948), RAMP1 (ENSG00000132329), RAMP2 (ENSG00000131477), RAMP3 (ENSG00000122679)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_358', 'drugName': 'Pramlintide', 'dru... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.941 | Q1 | Is NDUFA3 a druggable gene? | There are currently 2 approved drugs which target NDUFA3, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%NDUFA3 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1888', 'drugName': 'Metformin Hydrochloride', 'drugIsApproved': True, 'newLinkedTargets_string': 'GPD2 (ENSG00000115159), MT-ND6 (ENSG00000198695), NDUFA10 (ENSG00000130414), NDUFS8 (ENSG00000110717), MT-ND4L (ENSG00000212907), NDUFA6 (ENSG00000184983), MT-ND1 (ENSG00000198888), NDUFB6 (EN... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.676 | Q1 | Is IL17A a druggable gene? | There are currently 3 approved drugs which target IL17A, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%IL17A %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_306', 'drugName': 'Bimekizumab', 'drugIsApproved': True, 'newLinkedTargets_string': 'IL17F (ENSG00000112116), IL17A (ENSG00000112115)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_3578', 'drugName': 'Ixekizumab', 'drugIsApproved': True, 'newLinkedTargets_string': 'IL17A (ENSG... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1183 | Q1 | Is PSMD4 a druggable gene? | There are currently 4 approved drugs which target PSMD4, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%PSMD4 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_559', 'drugName': 'Bortezomib', 'drugIsApproved': True, 'newLinkedTargets_string': 'PSMD1 (ENSG00000173692), PSMB2 (ENSG00000126067), PSMB1 (ENSG00000008018), PSMB5 (ENSG00000100804), PSMB8 (ENSG00000204264), PSMB9 (ENSG00000240065), PSMB6 (ENSG00000142507), PSMD14 (ENSG00000115233), PSMA1... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.558 | Q1 | Is GRM5 a druggable gene? | There are currently no approved drugs targeting GRM5, but there are 9 drugs in clinical trials indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%GRM5 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_2800', 'drugName': 'Azd2066', 'drugIsApproved': False, 'newLinkedTargets_string': 'GRM5 (ENSG00000168959)', 'maxClinicalTrialPhase': 2}, {'UUID': 'DrugGeneTargets_v2_3225', 'drugName': 'Stx107', 'drugIsApproved': False, 'newLinkedTargets_string': 'GRM5 (ENSG00000168959)', 'maxClinicalTrial... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.936 | Q1 | Is NDUFA10 a druggable gene? | There are currently 2 approved drugs which target NDUFA10, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%NDUFA10 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1888', 'drugName': 'Metformin Hydrochloride', 'drugIsApproved': True, 'newLinkedTargets_string': 'GPD2 (ENSG00000115159), MT-ND6 (ENSG00000198695), NDUFA10 (ENSG00000130414), NDUFS8 (ENSG00000110717), MT-ND4L (ENSG00000212907), NDUFA6 (ENSG00000184983), MT-ND1 (ENSG00000198888), NDUFB6 (EN... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.135 | Q1 | Is CA3 a druggable gene? | There are currently 2 approved drugs which target CA3, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%CA3 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_6095', 'drugName': 'Sulthiame', 'drugIsApproved': True, 'newLinkedTargets_string': 'CA2 (ENSG00000104267), CA7 (ENSG00000168748), CA1 (ENSG00000133742), CA3 (ENSG00000164879), CA6 (ENSG00000131686), CA12 (ENSG00000074410), CA14 (ENSG00000118298), CA9 (ENSG00000107159), CA4 (ENSG00000167434... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1133 | Q1 | Is PRKAG3 a druggable gene? | There are currently no approved drugs targeting PRKAG3, but there is 1 drug in a clinical trial indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%PRKAG3 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_5888', 'drugName': 'Acadesine', 'drugIsApproved': False, 'newLinkedTargets_string': 'PRKAA2 (ENSG00000162409), PRKAB2 (ENSG00000131791), PRKAG1 (ENSG00000181929), PRKAG2 (ENSG00000106617), PRKAB1 (ENSG00000111725), PRKAA1 (ENSG00000132356), PRKAG3 (ENSG00000115592)', 'maxClinicalTrialPhase... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.828 | Q1 | Is LPAR1 a druggable gene? | There are currently no approved drugs targeting LPAR1, but there is 1 drug in a clinical trial indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%LPAR1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1832', 'drugName': 'Bms-986020', 'drugIsApproved': False, 'newLinkedTargets_string': 'LPAR1 (ENSG00000198121)', 'maxClinicalTrialPhase': 2}] | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.410 | Q1 | Is EPHA3 a druggable gene? | There is 1 drug, Vandetanib, that targets EPHA3, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%EPHA3 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1935', 'drugName': 'Vandetanib', 'drugIsApproved': True, 'newLinkedTargets_string': 'TEK (ENSG00000120156), ERBB2 (ENSG00000141736), EGFR (ENSG00000146648), ERBB4 (ENSG00000178568), ERBB3 (ENSG00000065361), EPHA2 (ENSG00000142627), EPHB2 (ENSG00000133216), EPHA5 (ENSG00000145242), EPHA4 (E... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.370 | Q1 | Is DPEP1 a druggable gene? | There are currently 2 approved drugs which target DPEP1, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%DPEP1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1365', 'drugName': 'Cilastatin', 'drugIsApproved': True, 'newLinkedTargets_string': 'DPEP1 (ENSG00000015413)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_185', 'drugName': 'Cilastatin Sodium', 'drugIsApproved': True, 'newLinkedTargets_string': 'DPEP1 (ENSG00000015413)', 'max... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.510 | Q1 | Is GAS6 a druggable gene? | There are currently no approved drugs targeting GAS6, but there is 1 drug in a clinical trial indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%GAS6 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_5288', 'drugName': 'Batiraxcept', 'drugIsApproved': False, 'newLinkedTargets_string': 'GAS6 (ENSG00000183087)', 'maxClinicalTrialPhase': 3}] | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1211 | Q1 | Is RARA a druggable gene? | There are currently 7 approved drugs which target RARA, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%RARA %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_343', 'drugName': 'Etretinate', 'drugIsApproved': True, 'newLinkedTargets_string': 'RXRB (ENSG00000204231), RARG (ENSG00000172819), RXRG (ENSG00000143171), RARB (ENSG00000077092), RARA (ENSG00000131759), RXRA (ENSG00000186350)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_508... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.507 | Q1 | Is GABRP a druggable gene? | There are currently 66 approved drugs which target GABRP, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%GABRP %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1494', 'drugName': 'Thiopental', 'drugIsApproved': True, 'newLinkedTargets_string': 'GABRA1 (ENSG00000022355), GABRB2 (ENSG00000145864), GABRG2 (ENSG00000113327), GABRB3 (ENSG00000166206), GABRA4 (ENSG00000109158), GABRG3 (ENSG00000182256), GABRQ (ENSG00000268089), GABRA3 (ENSG00000011677)... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1365 | Q1 | Is SLC22A12 a druggable gene? | There are currently 3 approved drugs which target SLC22A12, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%SLC22A12 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1001', 'drugName': 'Lesinurad', 'drugIsApproved': True, 'newLinkedTargets_string': 'SLC22A12 (ENSG00000197891)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_3284', 'drugName': 'Benzbromarone', 'drugIsApproved': True, 'newLinkedTargets_string': 'SLC22A12 (ENSG00000197891)', 'm... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.349 | Q1 | Is CYP3A43 a druggable gene? | There are currently 2 approved drugs which target CYP3A43, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%CYP3A43 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_2751', 'drugName': 'Ritonavir', 'drugIsApproved': True, 'newLinkedTargets_string': 'CYP3A4 (ENSG00000160868), CYP3A5 (ENSG00000106258), CYP3A43 (ENSG00000021461), CYP3A7 (ENSG00000160870)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_2752', 'drugName': 'Ritonavir', 'drugIsApp... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.388 | Q1 | Is EDNRB a druggable gene? | There are currently 5 approved drugs which target EDNRB, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%EDNRB %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1670', 'drugName': 'Sitaxentan', 'drugIsApproved': True, 'newLinkedTargets_string': 'EDNRB (ENSG00000136160), EDNRA (ENSG00000151617)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_3910', 'drugName': 'Ambrisentan', 'drugIsApproved': True, 'newLinkedTargets_string': 'EDNRB (ENS... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1 | Q1 | Is A2M a druggable gene? | There are currently 2 approved drugs which target A2M, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%A2M %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_2885', 'drugName': 'Technetium Tc 99M Succimer', 'drugIsApproved': True, 'newLinkedTargets_string': 'A2M (ENSG00000175899)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_4248', 'drugName': 'Technetium Succimer', 'drugIsApproved': True, 'newLinkedTargets_string': 'A2M (ENSG0000... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.362 | Q1 | Is DIO1 a druggable gene? | There is 1 drug, Propylthiouracil, that targets DIO1, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%DIO1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_394', 'drugName': 'Propylthiouracil', 'drugIsApproved': True, 'newLinkedTargets_string': 'TPO (ENSG00000115705), DIO1 (ENSG00000211452)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_395', 'drugName': 'Propylthiouracil', 'drugIsApproved': True, 'newLinkedTargets_string': 'TPO ... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.899 | Q1 | Is MMP7 a druggable gene? | There are currently 4 approved drugs which target MMP7, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%MMP7 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_285', 'drugName': 'Doxycycline Anhydrous', 'drugIsApproved': True, 'newLinkedTargets_string': 'MMP13 (ENSG00000137745), MMP8 (ENSG00000118113), MMP7 (ENSG00000137673), MMP1 (ENSG00000196611)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_3046', 'drugName': 'Doxycycline', 'drug... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.833 | Q1 | Is LTB4R a druggable gene? | There are currently no approved drugs targeting LTB4R, but there are 4 drugs in clinical trials indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%LTB4R %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1191', 'drugName': 'Nomacopan', 'drugIsApproved': False, 'newLinkedTargets_string': 'LTB4R2 (ENSG00000213906), LTB4R (ENSG00000213903), C5 (ENSG00000106804)', 'maxClinicalTrialPhase': 3}, {'UUID': 'DrugGeneTargets_v2_1192', 'drugName': 'Nomacopan', 'drugIsApproved': False, 'newLinkedTarget... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1451 | Q1 | Is TNFRSF8 a druggable gene? | There is 1 drug, Brentuximab Vedotin, that targets TNFRSF8, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%TNFRSF8 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1085', 'drugName': 'Brentuximab Vedotin', 'drugIsApproved': True, 'newLinkedTargets_string': 'TNFRSF8 (ENSG00000120949), TUBB4B (ENSG00000188229), TUBB1 (ENSG00000101162), TUBA3C (ENSG00000198033), TUBA4A (ENSG00000127824), TUBB3 (ENSG00000258947), TUBA1A (ENSG00000167552), TUBB4A (ENSG000... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.477 | Q1 | Is FNTB a druggable gene? | There is 1 drug, Lonafarnib, that targets FNTB, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%FNTB %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_5762', 'drugName': 'Lonafarnib', 'drugIsApproved': True, 'newLinkedTargets_string': 'FNTA (ENSG00000168522), FNTB (ENSG00000257365)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_3546', 'drugName': 'Tipifarnib', 'drugIsApproved': False, 'newLinkedTargets_string': 'FNTA (ENSG00... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1313 | Q1 | Is RRM1 a druggable gene? | There are currently 6 approved drugs which target RRM1, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%RRM1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_4', 'drugName': 'Gemcitabine Hydrochloride', 'drugIsApproved': True, 'newLinkedTargets_string': 'POLA1 (ENSG00000101868), POLD4 (ENSG00000175482), POLD3 (ENSG00000077514), POLD1 (ENSG00000062822), POLD2 (ENSG00000106628), POLE (ENSG00000177084), POLA2 (ENSG00000014138), PRIM1 (ENSG00000198... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.58 | Q1 | Is ALOX5 a druggable gene? | There are currently 9 approved drugs which target ALOX5, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%ALOX5 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_3724', 'drugName': 'Meclofenamate Sodium', 'drugIsApproved': True, 'newLinkedTargets_string': 'ALOX5 (ENSG00000012779), PTGS2 (ENSG00000073756), PTGS1 (ENSG00000095303)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_3016', 'drugName': 'Sulfasalazine', 'drugIsApproved': True, '... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.641 | Q1 | Is IFNA10 a druggable gene? | There are currently no approved drugs targeting IFNA10, but there are 2 drugs in clinical trials indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%IFNA10 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_5087', 'drugName': 'Sifalimumab', 'drugIsApproved': False, 'newLinkedTargets_string': 'IFNA6 (ENSG00000120235), IFNA8 (ENSG00000120242), IFNA5 (ENSG00000147873), IFNA10 (ENSG00000186803), IFNA2 (ENSG00000188379), IFNA1 (ENSG00000197919), IFNA13 (ENSG00000233816), IFNA7 (ENSG00000214042), I... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1339 | Q1 | Is SCN9A a druggable gene? | There are currently 78 approved drugs which target SCN9A, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%SCN9A %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_2948', 'drugName': 'Proparacaine Hydrochloride', 'drugIsApproved': True, 'newLinkedTargets_string': 'SCN1A (ENSG00000144285), SCN5A (ENSG00000183873), SCN4A (ENSG00000007314), SCN7A (ENSG00000136546), SCN2A (ENSG00000136531), SCN9A (ENSG00000169432), SCN3A (ENSG00000153253), SCN11A (ENSG00... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1073 | Q1 | Is PGF a druggable gene? | There is 1 drug, Aflibercept, that targets PGF, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%PGF %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_998', 'drugName': 'Aflibercept', 'drugIsApproved': True, 'newLinkedTargets_string': 'VEGFA (ENSG00000112715), PGF (ENSG00000119630)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_997', 'drugName': 'Aflibercept', 'drugIsApproved': True, 'newLinkedTargets_string': 'VEGFA (ENSG00... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1529 | Q1 | Is VKORC1 a druggable gene? | There are currently 7 approved drugs which target VKORC1, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%VKORC1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_5347', 'drugName': 'Warfarin Potassium', 'drugIsApproved': True, 'newLinkedTargets_string': 'VKORC1 (ENSG00000167397)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_1631', 'drugName': 'Dicumarol', 'drugIsApproved': True, 'newLinkedTargets_string': 'VKORC1 (ENSG00000167397)', '... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.174 | Q1 | Is CASP10 a druggable gene? | There are currently no approved drugs targeting CASP10, but there is 1 drug in a clinical trial indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%CASP10 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_45', 'drugName': 'Emricasan', 'drugIsApproved': False, 'newLinkedTargets_string': 'CASP4 (ENSG00000196954), CASP9 (ENSG00000132906), CASP3 (ENSG00000164305), CASP5 (ENSG00000137757), CASP6 (ENSG00000138794), CASP7 (ENSG00000165806), CASP8 (ENSG00000064012), CASP1 (ENSG00000137752), CASP2 (... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.452 | Q1 | Is FCGR2B a druggable gene? | There are currently no approved drugs targeting FCGR2B, but there is 1 drug in a clinical trial indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%FCGR2B %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_2610', 'drugName': 'Obexelimab', 'drugIsApproved': False, 'newLinkedTargets_string': 'CD19 (ENSG00000177455), FCGR2B (ENSG00000072694)', 'maxClinicalTrialPhase': 2}, {'UUID': 'DrugGeneTargets_v2_2611', 'drugName': 'Obexelimab', 'drugIsApproved': False, 'newLinkedTargets_string': 'CD19 (ENS... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.127 | Q1 | Is C3 a druggable gene? | There is 1 drug, Pegcetacoplan, that targets C3, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%C3 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_5818', 'drugName': 'Ocriplasmin', 'drugIsApproved': True, 'newLinkedTargets_string': 'FN1 (ENSG00000115414), COL1A2 (ENSG00000164692), COL1A1 (ENSG00000108821), COL2A1 (ENSG00000139219), COL3A1 (ENSG00000168542), COL4A1 (ENSG00000187498), COL5A1 (ENSG00000130635), COL6A1 (ENSG00000142156),... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1010 | Q1 | Is NRAS a druggable gene? | There are currently no approved drugs targeting NRAS, but there is 1 drug in a clinical trial indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%NRAS %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_3775', 'drugName': 'Salirasib', 'drugIsApproved': False, 'newLinkedTargets_string': 'HRAS (ENSG00000174775), NRAS (ENSG00000213281), KRAS (ENSG00000133703)', 'maxClinicalTrialPhase': 2}] | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.533 | Q1 | Is GPD2 a druggable gene? | There are currently 2 approved drugs which target GPD2, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%GPD2 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1886', 'drugName': 'Metformin', 'drugIsApproved': True, 'newLinkedTargets_string': 'GPD2 (ENSG00000115159), MT-ND6 (ENSG00000198695), NDUFA10 (ENSG00000130414), NDUFS8 (ENSG00000110717), MT-ND4L (ENSG00000212907), NDUFA6 (ENSG00000184983), MT-ND1 (ENSG00000198888), NDUFB6 (ENSG00000165264)... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.862 | Q1 | Is MAPK8 a druggable gene? | There are currently no approved drugs targeting MAPK8, but there are 3 drugs in clinical trials indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%MAPK8 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_2634', 'drugName': 'Cc-401', 'drugIsApproved': False, 'newLinkedTargets_string': 'MAPK9 (ENSG00000050748), MAPK8 (ENSG00000107643), MAPK10 (ENSG00000109339)', 'maxClinicalTrialPhase': 2}, {'UUID': 'DrugGeneTargets_v2_2632', 'drugName': 'Cc-401', 'drugIsApproved': False, 'newLinkedTargets_s... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.718 | Q1 | Is ITGA5 a druggable gene? | There are currently no approved drugs targeting ITGA5, but there are 3 drugs in clinical trials indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%ITGA5 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1021', 'drugName': 'Volociximab', 'drugIsApproved': False, 'newLinkedTargets_string': 'ITGB1 (ENSG00000150093), ITGA5 (ENSG00000161638)', 'maxClinicalTrialPhase': 3}, {'UUID': 'DrugGeneTargets_v2_174', 'drugName': 'Atn-161', 'drugIsApproved': False, 'newLinkedTargets_string': 'ITGB1 (ENSG0... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.92 | Q1 | Is ATR a druggable gene? | There are currently no approved drugs targeting ATR, but there are 4 drugs in clinical trials indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%ATR %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_4153', 'drugName': 'Ceralasertib', 'drugIsApproved': False, 'newLinkedTargets_string': 'ATR (ENSG00000175054)', 'maxClinicalTrialPhase': 3}, {'UUID': 'DrugGeneTargets_v2_3704', 'drugName': 'Berzosertib', 'drugIsApproved': False, 'newLinkedTargets_string': 'ATR (ENSG00000175054)', 'maxClini... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1487 | Q1 | Is TRPV4 a druggable gene? | There are currently 2 approved drugs which target TRPV4, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%TRPV4 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_5053', 'drugName': 'Butamben', 'drugIsApproved': True, 'newLinkedTargets_string': 'TRPA1 (ENSG00000104321), TRPV4 (ENSG00000111199)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_5054', 'drugName': 'Butamben', 'drugIsApproved': True, 'newLinkedTargets_string': 'TRPA1 (ENSG0000... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.183 | Q1 | Is CASP8 a druggable gene? | There are currently no approved drugs targeting CASP8, but there are 2 drugs in clinical trials indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%CASP8 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1848', 'drugName': 'Nivocasan', 'drugIsApproved': False, 'newLinkedTargets_string': 'CASP8 (ENSG00000064012), CASP1 (ENSG00000137752), CASP9 (ENSG00000132906)', 'maxClinicalTrialPhase': 2}, {'UUID': 'DrugGeneTargets_v2_1847', 'drugName': 'Nivocasan', 'drugIsApproved': False, 'newLinkedTarg... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.880 | Q1 | Is METAP1 a druggable gene? | There are currently no approved drugs targeting METAP1, but there is 1 drug in a clinical trial indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%METAP1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_582', 'drugName': 'Tosedostat', 'drugIsApproved': False, 'newLinkedTargets_string': 'ANPEP (ENSG00000166825), NPEPPS (ENSG00000141279), RNPEP (ENSG00000176393), METAP1 (ENSG00000164024), LNPEP (ENSG00000113441), DNPEP (ENSG00000123992), ENPEP (ENSG00000138792), XPNPEP1 (ENSG00000108039), L... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1035 | Q1 | Is PARP1 a druggable gene? | There are currently 7 approved drugs which target PARP1, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%PARP1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_4882', 'drugName': 'Niraparib Tosylate', 'drugIsApproved': True, 'newLinkedTargets_string': 'PARP2 (ENSG00000129484), PARP1 (ENSG00000143799)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_3166', 'drugName': 'Rucaparib', 'drugIsApproved': True, 'newLinkedTargets_string': 'PARP... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.791 | Q1 | Is KIR2DL2 a druggable gene? | There are currently no approved drugs targeting KIR2DL2, but there are 2 drugs in clinical trials indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%KIR2DL2 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_4725', 'drugName': 'Iph-2101', 'drugIsApproved': False, 'newLinkedTargets_string': 'KIR2DL2 (ENSG00000275546), KIR2DL1 (ENSG00000125498), KIR2DL3 (ENSG00000243772)', 'maxClinicalTrialPhase': 2}, {'UUID': 'DrugGeneTargets_v2_5180', 'drugName': 'Lirilumab', 'drugIsApproved': False, 'newLinke... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.416 | Q1 | Is EPHB1 a druggable gene? | There is 1 drug, Vandetanib, that targets EPHB1, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%EPHB1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1936', 'drugName': 'Vandetanib', 'drugIsApproved': True, 'newLinkedTargets_string': 'TEK (ENSG00000120156), ERBB2 (ENSG00000141736), EGFR (ENSG00000146648), ERBB4 (ENSG00000178568), ERBB3 (ENSG00000065361), EPHA2 (ENSG00000142627), EPHB2 (ENSG00000133216), EPHA5 (ENSG00000145242), EPHA4 (E... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.253 | Q1 | Is CFB a druggable gene? | There are currently no approved drugs targeting CFB, but there is 1 drug in a clinical trial indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%CFB %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_3164', 'drugName': 'Iptacopan', 'drugIsApproved': False, 'newLinkedTargets_string': 'CFB (ENSG00000243649)', 'maxClinicalTrialPhase': 3}] | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.70 | Q1 | Is APEX1 a druggable gene? | There are currently no approved drugs targeting APEX1, but there is 1 drug in a clinical trial indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%APEX1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_3210', 'drugName': 'Apx-3330', 'drugIsApproved': False, 'newLinkedTargets_string': 'APEX1 (ENSG00000100823)', 'maxClinicalTrialPhase': 2}] | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.808 | Q1 | Is LAMB2 a druggable gene? | There is 1 drug, Ocriplasmin, that targets LAMB2, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%LAMB2 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_5818', 'drugName': 'Ocriplasmin', 'drugIsApproved': True, 'newLinkedTargets_string': 'FN1 (ENSG00000115414), COL1A2 (ENSG00000164692), COL1A1 (ENSG00000108821), COL2A1 (ENSG00000139219), COL3A1 (ENSG00000168542), COL4A1 (ENSG00000187498), COL5A1 (ENSG00000130635), COL6A1 (ENSG00000142156),... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.133 | Q1 | Is CA14 a druggable gene? | There are currently 2 approved drugs which target CA14, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%CA14 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_6095', 'drugName': 'Sulthiame', 'drugIsApproved': True, 'newLinkedTargets_string': 'CA2 (ENSG00000104267), CA7 (ENSG00000168748), CA1 (ENSG00000133742), CA3 (ENSG00000164879), CA6 (ENSG00000131686), CA12 (ENSG00000074410), CA14 (ENSG00000118298), CA9 (ENSG00000107159), CA4 (ENSG00000167434... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.302 | Q1 | Is COL5A1 a druggable gene? | There are currently 2 approved drugs which target COL5A1, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%COL5A1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_5818', 'drugName': 'Ocriplasmin', 'drugIsApproved': True, 'newLinkedTargets_string': 'FN1 (ENSG00000115414), COL1A2 (ENSG00000164692), COL1A1 (ENSG00000108821), COL2A1 (ENSG00000139219), COL3A1 (ENSG00000168542), COL4A1 (ENSG00000187498), COL5A1 (ENSG00000130635), COL6A1 (ENSG00000142156),... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1092 | Q1 | Is PLA2G7 a druggable gene? | There are currently no approved drugs targeting PLA2G7, but there are 2 drugs in clinical trials indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%PLA2G7 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_5024', 'drugName': 'Darapladib', 'drugIsApproved': False, 'newLinkedTargets_string': 'PLA2G7 (ENSG00000146070)', 'maxClinicalTrialPhase': 3}, {'UUID': 'DrugGeneTargets_v2_3181', 'drugName': 'Rilapladib', 'drugIsApproved': False, 'newLinkedTargets_string': 'PLA2G7 (ENSG00000146070)', 'maxCl... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.328 | Q1 | Is CTAG1B a druggable gene? | There are currently no approved drugs targeting CTAG1B, but there is 1 drug in a clinical trial indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%CTAG1B %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_5339', 'drugName': 'Rasdegafusp Alfa', 'drugIsApproved': False, 'newLinkedTargets_string': 'LY75 (ENSG00000054219), CTAG1B (ENSG00000184033), CTAG1A (ENSG00000268651)', 'maxClinicalTrialPhase': 2}, {'UUID': 'DrugGeneTargets_v2_5340', 'drugName': 'Rasdegafusp Alfa', 'drugIsApproved': False,... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1501 | Q1 | Is TUBB1 a druggable gene? | There are currently 20 approved drugs which target TUBB1, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%TUBB1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1084', 'drugName': 'Brentuximab Vedotin', 'drugIsApproved': True, 'newLinkedTargets_string': 'TNFRSF8 (ENSG00000120949), TUBB4B (ENSG00000188229), TUBB1 (ENSG00000101162), TUBA3C (ENSG00000198033), TUBA4A (ENSG00000127824), TUBB3 (ENSG00000258947), TUBA1A (ENSG00000167552), TUBB4A (ENSG000... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1534 | Q1 | Is XPNPEP1 a druggable gene? | There are currently no approved drugs targeting XPNPEP1, but there is 1 drug in a clinical trial indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%XPNPEP1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_582', 'drugName': 'Tosedostat', 'drugIsApproved': False, 'newLinkedTargets_string': 'ANPEP (ENSG00000166825), NPEPPS (ENSG00000141279), RNPEP (ENSG00000176393), METAP1 (ENSG00000164024), LNPEP (ENSG00000113441), DNPEP (ENSG00000123992), ENPEP (ENSG00000138792), XPNPEP1 (ENSG00000108039), L... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.502 | Q1 | Is GABRD a druggable gene? | There are currently 66 approved drugs which target GABRD, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%GABRD %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1494', 'drugName': 'Thiopental', 'drugIsApproved': True, 'newLinkedTargets_string': 'GABRA1 (ENSG00000022355), GABRB2 (ENSG00000145864), GABRG2 (ENSG00000113327), GABRB3 (ENSG00000166206), GABRA4 (ENSG00000109158), GABRG3 (ENSG00000182256), GABRQ (ENSG00000268089), GABRA3 (ENSG00000011677)... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.343 | Q1 | Is CYP11B1 a druggable gene? | There are currently 4 approved drugs which target CYP11B1, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%CYP11B1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_3930', 'drugName': 'Levoketoconazole', 'drugIsApproved': True, 'newLinkedTargets_string': 'CYP11B1 (ENSG00000160882), CYP11B2 (ENSG00000179142), CYP17A1 (ENSG00000148795), CYP11A1 (ENSG00000140459)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_3932', 'drugName': 'Levoketocona... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.837 | Q1 | Is LY6E a druggable gene? | There are currently no approved drugs targeting LY6E, but there is 1 drug in a clinical trial indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%LY6E %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_831', 'drugName': 'Rg-7841', 'drugIsApproved': False, 'newLinkedTargets_string': 'LY6E (ENSG00000160932), TUBB4B (ENSG00000188229), TUBB1 (ENSG00000101162), TUBA3C (ENSG00000198033), TUBA4A (ENSG00000127824), TUBB3 (ENSG00000258947), TUBA1A (ENSG00000167552), TUBB4A (ENSG00000104833), TUBB... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.366 | Q1 | Is DMD a druggable gene? | There are currently 4 approved drugs which target DMD, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%DMD %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_3184', 'drugName': 'Eteplirsen', 'drugIsApproved': True, 'newLinkedTargets_string': 'DMD (ENSG00000198947)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_2014', 'drugName': 'Viltolarsen', 'drugIsApproved': True, 'newLinkedTargets_string': 'DMD (ENSG00000198947)', 'maxClinicalT... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.498 | Q1 | Is GABRA6 a druggable gene? | There are currently 67 approved drugs which target GABRA6, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%GABRA6 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1108', 'drugName': 'Temazepam', 'drugIsApproved': True, 'newLinkedTargets_string': 'GABRA1 (ENSG00000022355), GABRB2 (ENSG00000145864), GABRG2 (ENSG00000113327), GABRB3 (ENSG00000166206), GABRA4 (ENSG00000109158), GABRG3 (ENSG00000182256), GABRQ (ENSG00000268089), GABRA3 (ENSG00000011677),... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1430 | Q1 | Is THRB a druggable gene? | There are currently 6 approved drugs which target THRB, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%THRB %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_4368', 'drugName': 'Dextrothyroxine Sodium', 'drugIsApproved': True, 'newLinkedTargets_string': 'THRA (ENSG00000126351), THRB (ENSG00000151090)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_5964', 'drugName': 'Levothyroxine Sodium', 'drugIsApproved': True, 'newLinkedTargets_s... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.340 | Q1 | Is CXCR2 a druggable gene? | There are currently no approved drugs targeting CXCR2, but there are 6 drugs in clinical trials indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%CXCR2 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_2754', 'drugName': 'Reparixin', 'drugIsApproved': False, 'newLinkedTargets_string': 'CXCR1 (ENSG00000163464), CXCR2 (ENSG00000180871)', 'maxClinicalTrialPhase': 3}, {'UUID': 'DrugGeneTargets_v2_400', 'drugName': 'Ladarixin', 'drugIsApproved': False, 'newLinkedTargets_string': 'CXCR2 (ENSG0... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.423 | Q1 | Is ERAP1 a druggable gene? | There are currently no approved drugs targeting ERAP1, but there is 1 drug in a clinical trial indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%ERAP1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_582', 'drugName': 'Tosedostat', 'drugIsApproved': False, 'newLinkedTargets_string': 'ANPEP (ENSG00000166825), NPEPPS (ENSG00000141279), RNPEP (ENSG00000176393), METAP1 (ENSG00000164024), LNPEP (ENSG00000113441), DNPEP (ENSG00000123992), ENPEP (ENSG00000138792), XPNPEP1 (ENSG00000108039), L... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.166 | Q1 | Is CACNG7 a druggable gene? | There are currently 9 approved drugs which target CACNG7, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%CACNG7 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_142', 'drugName': 'Gabapentin', 'drugIsApproved': True, 'newLinkedTargets_string': 'CACNA1H (ENSG00000196557), CACNA2D1 (ENSG00000153956), CACNA1C (ENSG00000151067), CACNA2D3 (ENSG00000157445), CACNA1S (ENSG00000081248), CACNA2D2 (ENSG00000007402), CACNA1D (ENSG00000157388), CACNA1A (ENSG0... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.29 | Q1 | Is ADORA2A a druggable gene? | There are currently 11 approved drugs which target ADORA2A, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%ADORA2A %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_5472', 'drugName': 'Aminophylline', 'drugIsApproved': True, 'newLinkedTargets_string': 'PDE4A (ENSG00000065989), PDE4D (ENSG00000113448), PDE4B (ENSG00000184588), PDE4C (ENSG00000105650), PDE3A (ENSG00000172572), PDE3B (ENSG00000152270), ADORA1 (ENSG00000163485), ADORA2B (ENSG00000170425),... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.519 | Q1 | Is GHSR a druggable gene? | There are currently 2 approved drugs which target GHSR, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%GHSR %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_5129', 'drugName': 'Macimorelin', 'drugIsApproved': True, 'newLinkedTargets_string': 'GHSR (ENSG00000121853)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_942', 'drugName': 'Macimorelin Acetate', 'drugIsApproved': True, 'newLinkedTargets_string': 'GHSR (ENSG00000121853)', 'ma... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.195 | Q1 | Is CCR4 a druggable gene? | There is 1 drug, Mogamulizumab, that targets CCR4, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%CCR4 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_879', 'drugName': 'Mogamulizumab', 'drugIsApproved': True, 'newLinkedTargets_string': 'CCR4 (ENSG00000183813)', 'maxClinicalTrialPhase': 4}] | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1116 | Q1 | Is PPAT a druggable gene? | There are currently 3 approved drugs which target PPAT, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%PPAT %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_5406', 'drugName': 'Mercaptopurine', 'drugIsApproved': True, 'newLinkedTargets_string': 'PPAT (ENSG00000128059)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_2137', 'drugName': 'Mercaptopurine', 'drugIsApproved': True, 'newLinkedTargets_string': 'PPAT (ENSG00000128059)', 'max... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1395 | Q1 | Is SRD5A3 a druggable gene? | There are currently 2 approved drugs which target SRD5A3, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%SRD5A3 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_6320', 'drugName': 'Abiraterone', 'drugIsApproved': True, 'newLinkedTargets_string': 'AR (ENSG00000169083), CYP17A1 (ENSG00000148795), SRD5A1 (ENSG00000145545), SRD5A2 (ENSG00000277893), SRD5A3 (ENSG00000128039)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_433', 'drugName': ... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.950 | Q1 | Is NDUFAF1 a druggable gene? | There are currently 2 approved drugs which target NDUFAF1, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%NDUFAF1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1888', 'drugName': 'Metformin Hydrochloride', 'drugIsApproved': True, 'newLinkedTargets_string': 'GPD2 (ENSG00000115159), MT-ND6 (ENSG00000198695), NDUFA10 (ENSG00000130414), NDUFS8 (ENSG00000110717), MT-ND4L (ENSG00000212907), NDUFA6 (ENSG00000184983), MT-ND1 (ENSG00000198888), NDUFB6 (EN... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1394 | Q1 | Is SRD5A2 a druggable gene? | There are currently 3 approved drugs which target SRD5A2, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%SRD5A2 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_6321', 'drugName': 'Abiraterone', 'drugIsApproved': True, 'newLinkedTargets_string': 'AR (ENSG00000169083), CYP17A1 (ENSG00000148795), SRD5A1 (ENSG00000145545), SRD5A2 (ENSG00000277893), SRD5A3 (ENSG00000128039)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_5461', 'drugName':... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.171 | Q1 | Is CALCRL a druggable gene? | There are currently 5 approved drugs which target CALCRL, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%CALCRL %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_3190', 'drugName': 'Rimegepant Sulfate', 'drugIsApproved': True, 'newLinkedTargets_string': 'CALCRL (ENSG00000064989)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_5361', 'drugName': 'Erenumab', 'drugIsApproved': True, 'newLinkedTargets_string': 'CALCRL (ENSG00000064989)', 'm... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.169 | Q1 | Is CALCB a druggable gene? | There are currently 3 approved drugs which target CALCB, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%CALCB %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1901', 'drugName': 'Galcanezumab', 'drugIsApproved': True, 'newLinkedTargets_string': 'CALCA (ENSG00000110680), CALCB (ENSG00000175868)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_5545', 'drugName': 'Fremanezumab', 'drugIsApproved': True, 'newLinkedTargets_string': 'CALCA (... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.656 | Q1 | Is IFNG a druggable gene? | There is 1 drug, Emapalumab, that targets IFNG, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%IFNG %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_3856', 'drugName': 'Emapalumab', 'drugIsApproved': True, 'newLinkedTargets_string': 'IFNG (ENSG00000111537)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_4201', 'drugName': 'Fontolizumab', 'drugIsApproved': False, 'newLinkedTargets_string': 'IFNG (ENSG00000111537)', 'maxClini... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.175 | Q1 | Is CASP12 a druggable gene? | There are currently no approved drugs targeting CASP12, but there is 1 drug in a clinical trial indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%CASP12 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_45', 'drugName': 'Emricasan', 'drugIsApproved': False, 'newLinkedTargets_string': 'CASP4 (ENSG00000196954), CASP9 (ENSG00000132906), CASP3 (ENSG00000164305), CASP5 (ENSG00000137757), CASP6 (ENSG00000138794), CASP7 (ENSG00000165806), CASP8 (ENSG00000064012), CASP1 (ENSG00000137752), CASP2 (... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.521 | Q1 | Is GLA a druggable gene? | There are currently 2 approved drugs which target GLA, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%GLA %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_3147', 'drugName': 'Migalastat', 'drugIsApproved': True, 'newLinkedTargets_string': 'GLA (ENSG00000102393)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_549', 'drugName': 'Migalastat Hydrochloride', 'drugIsApproved': True, 'newLinkedTargets_string': 'GLA (ENSG00000102393)', '... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1244 | Q1 | Is RPL23A a druggable gene? | There is 1 drug, Ataluren, that targets RPL23A, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%RPL23A %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_3776', 'drugName': 'Ataluren', 'drugIsApproved': True, 'newLinkedTargets_string': 'RPSA (ENSG00000168028), RPS27 (ENSG00000177954), RPS6 (ENSG00000137154), RPS2 (ENSG00000140988), RPS3 (ENSG00000149273), RPS3A (ENSG00000145425), RPS4X (ENSG00000198034), RPS4Y1 (ENSG00000129824), RPS5 (ENSG... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1210 | Q1 | Is RAMP3 a druggable gene? | There are currently 2 approved drugs which target RAMP3, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%RAMP3 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_359', 'drugName': 'Pramlintide', 'drugIsApproved': True, 'newLinkedTargets_string': 'CALCR (ENSG00000004948), RAMP1 (ENSG00000132329), RAMP2 (ENSG00000131477), RAMP3 (ENSG00000122679)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_2395', 'drugName': 'Pramlintide Acetate', 'dru... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.917 | Q1 | Is MTOR a druggable gene? | There are currently 2 approved drugs which target MTOR, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%MTOR %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1725', 'drugName': 'Perhexiline Maleate', 'drugIsApproved': True, 'newLinkedTargets_string': 'MTOR (ENSG00000198793), CPT2 (ENSG00000157184), CPT1B (ENSG00000205560)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_919', 'drugName': 'Perhexiline', 'drugIsApproved': True, 'newLin... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.494 | Q1 | Is GABRA2 a druggable gene? | There are currently 68 approved drugs which target GABRA2, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%GABRA2 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_2854', 'drugName': 'Chlordiazepoxide Hydrochloride', 'drugIsApproved': True, 'newLinkedTargets_string': 'GABRA1 (ENSG00000022355), GABRB2 (ENSG00000145864), GABRG2 (ENSG00000113327), GABRB3 (ENSG00000166206), GABRA4 (ENSG00000109158), GABRG3 (ENSG00000182256), GABRQ (ENSG00000268089), GABR... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.958 | Q1 | Is NDUFB3 a druggable gene? | There are currently 2 approved drugs which target NDUFB3, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%NDUFB3 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1888', 'drugName': 'Metformin Hydrochloride', 'drugIsApproved': True, 'newLinkedTargets_string': 'GPD2 (ENSG00000115159), MT-ND6 (ENSG00000198695), NDUFA10 (ENSG00000130414), NDUFS8 (ENSG00000110717), MT-ND4L (ENSG00000212907), NDUFA6 (ENSG00000184983), MT-ND1 (ENSG00000198888), NDUFB6 (EN... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.74 | Q1 | Is APOB a druggable gene? | There are currently 2 approved drugs which target APOB, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%APOB %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_3718', 'drugName': 'Mipomersen Sodium', 'drugIsApproved': True, 'newLinkedTargets_string': 'APOB (ENSG00000084674)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_5688', 'drugName': 'Mipomersen', 'drugIsApproved': True, 'newLinkedTargets_string': 'APOB (ENSG00000084674)', 'maxC... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1285 | Q1 | Is RPS2 a druggable gene? | There is 1 drug, Ataluren, that targets RPS2, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%RPS2 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_3776', 'drugName': 'Ataluren', 'drugIsApproved': True, 'newLinkedTargets_string': 'RPSA (ENSG00000168028), RPS27 (ENSG00000177954), RPS6 (ENSG00000137154), RPS2 (ENSG00000140988), RPS3 (ENSG00000149273), RPS3A (ENSG00000145425), RPS4X (ENSG00000198034), RPS4Y1 (ENSG00000129824), RPS5 (ENSG... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.591 | Q1 | Is HGF a druggable gene? | There are currently no approved drugs targeting HGF, but there are 2 drugs in clinical trials indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%HGF %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1237', 'drugName': 'Rilotumumab', 'drugIsApproved': False, 'newLinkedTargets_string': 'HGF (ENSG00000019991)', 'maxClinicalTrialPhase': 3}, {'UUID': 'DrugGeneTargets_v2_5496', 'drugName': 'Ficlatuzumab', 'drugIsApproved': False, 'newLinkedTargets_string': 'HGF (ENSG00000019991)', 'maxClini... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.755 | Q1 | Is KCNH1 a druggable gene? | There are currently 5 approved drugs which target KCNH1, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%KCNH1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_5118', 'drugName': 'Guanidine Hydrochloride', 'drugIsApproved': True, 'newLinkedTargets_string': 'KCNQ1 (ENSG00000053918), KCND3 (ENSG00000171385), KCNH2 (ENSG00000055118), KCNA2 (ENSG00000177301), KCNA1 (ENSG00000111262), KCNQ2 (ENSG00000075043), KCNQ3 (ENSG00000184156), KCNA7 (ENSG000001... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.661 | Q1 | Is IGF1R a druggable gene? | There are currently 3 approved drugs which target IGF1R, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%IGF1R %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_672', 'drugName': 'Mecasermin Rinfabate', 'drugIsApproved': True, 'newLinkedTargets_string': 'IGF1R (ENSG00000140443)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_1336', 'drugName': 'Teprotumumab', 'drugIsApproved': True, 'newLinkedTargets_string': 'IGF1R (ENSG00000140443)',... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.847 | Q1 | Is MAP2K1 a druggable gene? | There are currently 7 approved drugs which target MAP2K1, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%MAP2K1 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_6005', 'drugName': 'Cobimetinib Fumarate', 'drugIsApproved': True, 'newLinkedTargets_string': 'MAP2K1 (ENSG00000169032), MAP2K2 (ENSG00000126934)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_3657', 'drugName': 'Cobimetinib', 'drugIsApproved': True, 'newLinkedTargets_string':... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.236 | Q1 | Is CDK15 a druggable gene? | There are currently no approved drugs targeting CDK15, but there are 4 drugs in clinical trials indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%CDK15 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1429', 'drugName': 'Roniciclib', 'drugIsApproved': False, 'newLinkedTargets_string': 'CDK1 (ENSG00000170312), CDK4 (ENSG00000135446), CDK2 (ENSG00000123374), CDK5 (ENSG00000164885), CDK6 (ENSG00000105810), CDK7 (ENSG00000134058), CDK3 (ENSG00000250506), CDK16 (ENSG00000102225), CDK18 (ENSG... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.737 | Q1 | Is KCNA4 a druggable gene? | There are currently 5 approved drugs which target KCNA4, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%KCNA4 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_5118', 'drugName': 'Guanidine Hydrochloride', 'drugIsApproved': True, 'newLinkedTargets_string': 'KCNQ1 (ENSG00000053918), KCND3 (ENSG00000171385), KCNH2 (ENSG00000055118), KCNA2 (ENSG00000177301), KCNA1 (ENSG00000111262), KCNQ2 (ENSG00000075043), KCNQ3 (ENSG00000184156), KCNA7 (ENSG000001... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.216 | Q1 | Is CD40LG a druggable gene? | There are currently no approved drugs targeting CD40LG, but there are 6 drugs in clinical trials indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%CD40LG %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_230', 'drugName': 'Ruplizumab', 'drugIsApproved': False, 'newLinkedTargets_string': 'CD40LG (ENSG00000102245)', 'maxClinicalTrialPhase': 3}, {'UUID': 'DrugGeneTargets_v2_4952', 'drugName': 'Dapirolizumab Pegol', 'drugIsApproved': False, 'newLinkedTargets_string': 'CD40LG (ENSG00000102245)'... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.164 | Q1 | Is CACNG5 a druggable gene? | There are currently 9 approved drugs which target CACNG5, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%CACNG5 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_142', 'drugName': 'Gabapentin', 'drugIsApproved': True, 'newLinkedTargets_string': 'CACNA1H (ENSG00000196557), CACNA2D1 (ENSG00000153956), CACNA1C (ENSG00000151067), CACNA2D3 (ENSG00000157445), CACNA1S (ENSG00000081248), CACNA2D2 (ENSG00000007402), CACNA1D (ENSG00000157388), CACNA1A (ENSG0... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.134 | Q1 | Is CA2 a druggable gene? | There are currently 10 approved drugs which target CA2, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%CA2 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_469', 'drugName': 'Acetazolamide', 'drugIsApproved': True, 'newLinkedTargets_string': 'CA12 (ENSG00000074410), CA2 (ENSG00000104267), CA4 (ENSG00000167434), CA1 (ENSG00000133742)', 'maxClinicalTrialPhase': 4}, {'UUID': 'DrugGeneTargets_v2_468', 'drugName': 'Acetazolamide', 'drugIsApproved'... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1129 | Q1 | Is PRKACB a druggable gene? | There are currently no approved drugs targeting PRKACB, but there is 1 drug in a clinical trial indicating that it may be a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%PRKACB %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1835', 'drugName': 'Gsk-690693', 'drugIsApproved': False, 'newLinkedTargets_string': 'PRKACB (ENSG00000142875), PRKACA (ENSG00000072062), PRKACG (ENSG00000165059), AKT2 (ENSG00000105221), AKT3 (ENSG00000117020), AKT1 (ENSG00000142208), PRKD3 (ENSG00000115825), PRKCI (ENSG00000163558), PRKC... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.224 | Q1 | Is CD79B a druggable gene? | There is 1 drug, Polatuzumab Vedotin, that targets CD79B, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%CD79B %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_560', 'drugName': 'Polatuzumab Vedotin', 'drugIsApproved': True, 'newLinkedTargets_string': 'CD79B (ENSG00000007312), TUBB4B (ENSG00000188229), TUBB1 (ENSG00000101162), TUBA3C (ENSG00000198033), TUBA4A (ENSG00000127824), TUBB3 (ENSG00000258947), TUBA1A (ENSG00000167552), TUBB4A (ENSG000001... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.1258 | Q1 | Is RPL36 a druggable gene? | There is 1 drug, Ataluren, that targets RPL36, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%RPL36 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_3776', 'drugName': 'Ataluren', 'drugIsApproved': True, 'newLinkedTargets_string': 'RPSA (ENSG00000168028), RPS27 (ENSG00000177954), RPS6 (ENSG00000137154), RPS2 (ENSG00000140988), RPS3 (ENSG00000149273), RPS3A (ENSG00000145425), RPS4X (ENSG00000198034), RPS4Y1 (ENSG00000129824), RPS5 (ENSG... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
Q1.939 | Q1 | Is NDUFA13 a druggable gene? | There are currently 2 approved drugs which target NDUFA13, indicating that it is a druggable gene. | SELECT DISTINCT UUID, drugName, drugIsApproved, newLinkedTargets_string, maxClinicalTrialPhase
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE newLinkedTargets_string LIKE "%NDUFA13 %"
ORDER BY maxClinicalTrialPhase DESC
LIMIT 100
| [{'UUID': 'DrugGeneTargets_v2_1888', 'drugName': 'Metformin Hydrochloride', 'drugIsApproved': True, 'newLinkedTargets_string': 'GPD2 (ENSG00000115159), MT-ND6 (ENSG00000198695), NDUFA10 (ENSG00000130414), NDUFS8 (ENSG00000110717), MT-ND4L (ENSG00000212907), NDUFA6 (ENSG00000184983), MT-ND1 (ENSG00000198888), NDUFB6 (EN... | general | Similarity Search, Order By, Distinct | Approval Status, Genetic Target |
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