0
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).\tIncreased\tserum\tosmolality\tor\tdecreased\tblood\tvolume\tleads\nto\tthe\trelease\tof\tantidiuretic\thormone\twhich\tsignals\tthe\tkidneys\tto\tconserve\n\twater.\tIn\tthe\tpresence\nof\tlow\tECF\tvolume,\tthe\tkidneys\trelease\trenin\tto\tproduce\tangiotensin\tII\t(the\t\nrenin-angiotensin\nsystem
[ 0.023199066519737244, -0.09040517359972, 0.025899367406964302, 0.008688261732459068, -0.05316770821809769, 0.049406200647354126, 0.07511163502931595, 0.024826116859912872, 0.04198610037565231, 0.04867261275649071, 0.07862352579832077, -0.02223902754485607, 0.021718787029385567, 0.048863079...
renin-angiotensin\nsystem\n).\tAngiotensin\tII\thas\tseveral\tfunctions,\tincluding\tstimulation\tof\tvasoconstriction\tand\tthe\nthirst\tcenters.\nWater\tintake\nThirst\tis\tregulated\tby\tthe\thypothalamus\tand\tcontrols\twater\tintake\tin\thealthy\tindividuals.\tSensitivity\nto\tthirst\tis\tdecreased\tin\tolder\tind...
[ 0.018215825781226158, -0.056302014738321304, 0.08743416517972946, -0.024449674412608147, -0.08218716084957123, 0.010433110408484936, 0.08778179436922073, 0.009683579206466675, 0.015652181580662727, 0.04891592636704445, 0.07935502380132675, -0.044377412647008896, -0.0017319100443273783, 0.0...
to\tthirst\tis\tdecreased\tin\tolder\tindividuals,\tchronically\n\tor\tacutely\till\tpatients,\tinfants,\tand\tathletes\nleading\tto\ta\thigher\tpotential\tfor\twater\tdeficits.\tSources\tof\twater\tinclude\tfluids\t(oral,\tenteral\ttube\nfeeding,\tparenteral\tfluids),\tfood,\tand\toxidative\tmetabolism\t(\nTables\t3.1...
[ -0.00877793412655592, -0.05481605604290962, 0.04201439395546913, -0.03518823906779289, -0.08783748000860214, -0.006242838688194752, 0.08918984234333038, 0.03840329870581627, -0.0094603868201375, 0.027955379337072372, 0.07459227740764618, -0.04135353863239288, 0.04235106334090233, 0.0565730...
,\t\n3.2\n,\tand\t\n3.3\n).\tThe\toxidation\tof\nfoods\tin\tthe\tbody\tproduces\t\nmetabolic\twater\n\tas\tan\tend\tproduct.\tThe\toxidation\tof\t100\tg\tof\tfat,\ncarbohydrate,\tor\tprotein\tyields\t107,\t55,\tor\t41\tg\n\tof\twater,\trespectively,\tfor\ta\ttotal\tof\tapproximately\n200\tto\t300\tmL/day\t(\nWhitmire,\...
[ -0.054195135831832886, -0.037948232144117355, 0.03158554434776306, -0.03730858117341995, -0.03843448683619499, -0.031100763007998466, 0.0770050436258316, 0.022394327446818352, -0.025448041036725044, 0.00366424722597003, 0.09933701902627945, -0.0762973502278328, 0.037860408425331116, 0.0392...
Canada,\t2015\n).\nTABLE\t3.1\nContent\tof\tCommon\tIntravenous\tFluids\nFluid\nDextrose\n(g/L)\nSodium\n(mEq/L)\nChloride\n(mEq/L)\nAdditional\tComponents\n(mEq/L)\n0.45%\tNaCl\n0\n77\n77\nn/a\n0.9%\tNaCl\n0\n154\n154\nn/a\n3%\tSaline\n0\n513\n513\nn/a\n5%\tDextrose\tin\nwater\n50\n0\n0\nn/a\nD\n5\n0.45%\tNaCl\n50\n77...
[ -0.03374842181801796, -0.07624198496341705, 0.008163431659340858, -0.03739459440112114, -0.025781700387597084, -0.02620377391576767, 0.040457963943481445, 0.013019866310060024, -0.024535929784178734, 0.0532187893986702, 0.03380611911416054, -0.10466545075178146, 0.026411324739456177, 0.072...
5\n0.9%\tNaCl\n50\n154\n154\nn/a\n10%\tDextrose\n100\n0\n0\nn/a\nLactated\tRinger’s\n(LR)\n0\n130\n109\nPotassium\t4\nCalcium\t3\nLactate\t28\nD\n5\nLR\n50\n130\n109\nPotassium\n\t4\nCalcium\t3\nLactate\t28
[ -0.07111004739999771, -0.023452112451195717, -0.039621882140636444, -0.08019618690013885, -0.05076257139444351, 0.012090339325368404, 0.013032648712396622, 0.08787908405065536, -0.018248261883854866, 0.042143311351537704, 0.04568188637495041, -0.1446671038866043, -0.06067543104290962, 0.05...
TABLE\t3.2\nPercentage\tof\tWater\tin\tCommon\tFoods\nFood\nPercentage\nLettuce,\ticeberg\n96\nCelery\n95\nCucumbers\n95\nCabbage,\traw\n92\nWatermelon\n92\nBroccoli,\tboiled\n91\nMilk,\tnonfat\n91\nSpinach\n91\nGreen\tbeans,\tboiled\n89\nCarrots,\traw\n88\nOranges\n87\nCereals,\tcooked\n85\nApples,\traw,\twithout\tski...
[ -0.03635049983859062, -0.04678243398666382, -0.0363440103828907, -0.051727887243032455, -0.021973730996251106, -0.028274623677134514, 0.03700300306081772, -0.010376115329563618, -0.07349953800439835, 0.015053626149892807, 0.0704629048705101, -0.09792570024728775, 0.020961521193385124, 0.03...
Grapes\n81\nPotatoes,\tboiled\n77\nEggs\n75\nBananas\n74\nFish,\thaddock,\tbaked\n74\nChicken,\troasted,\twhite\tmeat\n70\nCorn,\tboiled\n65\nBeef,\tsirloin\n59\nCheese,\tSwiss\n38\nBread,\twhite\n37\nCake,\tangel\tfood\n34\nButter\n16\nAlmonds,\tblanched\n5\nSaltines\n3\nSugar,\twhite\n1\nOils\n0
[ -0.035601984709501266, 0.005764346569776535, -0.02799653820693493, -0.00678609311580658, -0.0439179353415966, 0.030609726905822754, 0.039359044283628464, -0.024159938097000122, -0.11125742644071579, 0.03949311375617981, 0.06917987763881683, -0.07534896582365036, 0.011272935196757317, 0.010...
34\nButter\n16\nAlmonds,\tblanched\n5\nSaltines\n3\nSugar,\twhite\n1\nOils\n0\nFrom\tU.S.\tDepartment\tof\tAgriculture\t(USDA),\tAgricultural\tResearch\tService\t(ARS):\tNutrient\tdatabase\tfor\tstandard\treference.\nhttp://ndb.nal.usda.gov\n.\nTABLE\n\t3.3\nWater\tContent\tof\tEnteral\tNutrition\tFormulations\nEnteral...
[ 0.03290406987071037, -0.07013271749019623, -0.03449903801083565, -0.03721492737531662, -0.023360878229141235, -0.08239009976387024, -0.014480065554380417, 0.023689759895205498, -0.053558897227048874, 0.060338109731674194, 0.0187335517257452, -0.11285833269357681, 0.009109456092119217, 0.00...
Percentage\tof\tFree\tWater\n1.0\tkcal/mL\n84%\n1.2\tkcal/mL\n81%\n1.5\tkcal/mL\n76%\n2.0\tkcal/mL\n69%\nTonicity\tof\tbody\tfluids\tcan\tbe\tmeasured\t(serum\tosmolality)\tor\testimated\tfrom\tthe\tfollowing\nformula:\nCLINICAL\tINSIGHT\nOsmotic\tForces\nOsmotic\tpressure\n\tis\tdirectly\tproportional\tto\t\nthe\tnumb...
[ 0.024465544149279594, -0.11034710705280304, -0.021561574190855026, -0.006833713501691818, 0.009073969908058643, -0.029018577188253403, 0.06854157894849777, 0.10597480088472366, -0.021678974851965904, 0.009182917885482311, 0.07219448685646057, -0.07195857167243958, 0.01982644759118557, 0.06...
the\tnumber\tof\tparticles\tin\tsolution\tand\tusually\nrefers\tto\tthe\tpressure\tat\tthe\tcell\tmembrane.\tOsmotic\tpressure\tof\tintracellular\tfluid\tis\ta\tfunction\tof\nits\tpotassium\tcontent\tbecause\tpotassium\tis\n\tthe\tpredominant\tcation\tthere.\tIn\tcontrast,\tthe\tosmotic
[ 0.016636444255709648, -0.0738588497042656, 0.018111446872353554, -0.007662814576178789, -0.08293376117944717, 0.011510651558637619, 0.10348865389823914, 0.02507900260388851, 0.036025650799274445, 0.04514074698090553, 0.07475176453590393, -0.07824832201004028, 0.014493657276034355, 0.053488...
pressure\tof\textracellular\tfluid\t(ECF)\tmay\tbe\tconsidered\trelative\tto\tits\tsodium\tcontent\tbecause\nsodium\tis\tthe\tmajor\tcation\tpresent\tin\tECF.\tAlthough\tvariations\tin\tthe\tdistribution\tof\tsodium\tand\npotassium\tions\tare\tthe\tprincipal\tcauses\tof\twater\tshifts\tbetween\tthe\tvarious\tfluid\tcom...
[ -0.023798516020178795, -0.07573901861906052, 0.051816266030073166, -0.031639378517866135, -0.02103620581328869, 0.0016534350579604506, 0.09567943960428238, -0.021924281492829323, 0.02092551998794079, 0.0337795615196228, 0.06629662960767746, -0.0812443196773529, 0.05301294103264809, 0.04996...
chloride\tand\tphosphate\talso\tinfluence\twater\tbalance.\tProteins\n\tcannot\tdiffuse\tbecause\tof\ttheir\tsize\nand\tthus\talso\tplay\ta\tkey\trole\tin\tmaintaining\tosmotic\tequilibrium.\t\nOncotic\tpressure\n,\tor\t\ncolloidal\nosmotic\tpressure\n,\tis\tthe\tpressure\tat\tthe\tcapillary\tmembrane.\tIt\tis\tmaintai...
[ -0.006843120325356722, -0.10014332830905914, 0.03518972545862198, -0.06497865170240402, -0.07352837920188904, 0.019990717992186546, 0.12147527188062668, 0.02545689232647419, 0.021439483389258385, 0.03508652746677399, 0.07262887805700302, -0.05118504911661148, 0.06507012248039246, 0.0461264...
proteins\tin\tthe\tplasma\tand\tinterstitial\tfluids.\tOncotic\tpressure\thelps\tretain\twater\twithin\tblood\nvessels,\tpreventing\tits\tleakage\tfrom\tplasma\tinto\tthe\tinterstitial\tspaces.\n\tIn\tpatients\twith\tan\nexceptionally\tlow\tplasma\tprotein\tcontent,\tsuch\tas\tthose\twho\tare\tunder\tphysiologic\tstres...
[ -0.0033685797825455666, -0.050032999366521835, 0.05558854714035988, -0.014631274156272411, -0.07457428425550461, -0.0045867846347391605, 0.10906719416379929, 0.05620119348168373, -0.0015721633099019527, 0.03684906288981438, 0.10436668246984482, -0.037809520959854126, 0.02196260169148445, 0...
certain\tdiseases,\twater\tleaks\tinto\tthe\tinterstitial\tspaces,\tcausing\tedema\tor\tthird\tspacing;\tthus\tthe\nfluid\tis\tcalled\t\n“third\tspace”\tfluid\n.\nOsmoles\tand\tmilliosmoles\nConcentrations\tof\tindividual\tionic\tconstituents\tof\textracellular\tor\tintracellular\tfluids\tare\nexpressed\tin\tterms\tof\...
[ -0.05786975100636482, -0.07293104380369186, 0.02262810803949833, -0.05732808634638786, -0.05282439664006233, -0.03918083384633064, 0.07347942888736725, 0.015197313390672207, 0.003629920072853565, 0.030605534091591835, 0.096468485891819, -0.03704941272735596, 0.07487974315881729, 0.03491183...
milliosmoles\tper\tliter\t(mOsm/L).\tOne\tmole\tequals\tthe\tgram\tmolecular\nweight\tof\ta\tsubstance;\twhen\tdissolved\tin\t1\tL\tof\twater,\tit\tbecomes\t1\tosmole\t(Osm).\tOne\nmilliosmole\t(mOsm)\tequals\t1/1000th\tof\tan\tosmole.\nOsmolality\n\tis\ta\tmeasure\tof\tthe\tosmotically\tactive\tparticles\tper\tkilogra...
[ -0.027896495535969734, -0.05167825520038605, 0.044199030846357346, -0.014775616116821766, -0.08199535310268402, -0.03708648681640625, 0.06159387156367302, 0.003111044643446803, 0.004410312045365572, 0.022993505001068115, 0.10495219379663467, -0.07507399469614029, 0.09174492955207825, 0.034...
the\tparticles\tare\tdispersed.\tIt\tis\texpressed\tas\tmilliosmoles\tof\tsolute\tper\tkilogram\tof\tsolvent\n(mOsm/kg).\t\nOsmolarity\n\tis\tthe\tterm\tformerly\tused\tto\tdescribe\tconcentration—milliosmoles\tper\nliter\tof\tthe\tentire\tsolution—but\tosmolality\tis\tnow\tthe\tmeasurement\tfor\tmost\tclinical\twork.
[ 0.016195259988307953, -0.04055798798799515, 0.03208469972014427, -0.034942783415317535, -0.08293135464191437, -0.033221788704395294, 0.04847351834177971, 0.014821196906268597, 0.029133334755897522, 0.06349589675664902, 0.09435026347637177, -0.04814683273434639, 0.07419896125793457, 0.03222...
However,\tin\treference\tto\tcertain\tconditions\tsuch\tas\thyperlipidemia,\tit\tmakes\ta\tdifference\twhether\nosmolality\tis\tstated\tas\tmilliosmoles\tper\tkilogram\tof\tsolvent\tor\tper\tliter\tof\tsolution.\nThe\taverage\tsum\tof\tthe\tconcentration\n\tof\tall\tthe\tcations\tin\tserum\tis\tabout\t150\tmEq/L.\tThe\...
[ 0.035010963678359985, -0.04357168450951576, 0.027546914294362068, -0.07810017466545105, -0.08195751905441284, -0.01858578808605671, 0.05690637603402138, 0.00942611787468195, 0.06127627193927765, 0.06294961273670197, 0.1089920923113823, -0.01465518493205309, 0.05295572802424431, 0.056742399...
of\tall\tthe\tcations\tin\tserum\tis\tabout\t150\tmEq/L.\tThe\tcation\nconcentration\tis\tbalanced\tby\t150\tmEq/L\tof\tanions,\tyielding\ta\ttotal\tserum\tosmolality\tof\tabout\t300\nmOsm/L.\tAn\tosmolar\timbalance\tis\tcaused\tby\ta\tgain\tor\tloss\tof\twater\trelative\tto\ta\tsolute.\tAn\nosmolality\tof\tless\tthan\...
[ 0.0318998247385025, -0.019485479220747948, 0.04033592343330383, -0.060127343982458115, -0.057564567774534225, -0.012362337671220303, 0.06533908098936081, -0.009724455885589123, 0.01044459082186222, 0.05188851058483124, 0.0666603371500969, -0.039888009428977966, 0.06993561238050461, 0.02634...
than\t300\tmOsm/L\tindicates\ta\twater\tdeficit.\nWater\n\tintoxication\tand\tfluid\toverload\nWater\tintoxication\toccurs\tas\ta\tresult\tof\twater\tintake\tin\texcess\tof\tthe\tbody’s\tability\tto\texcrete\twater.\nThe\tincreased\t\nICF\n\tvolume\tis\taccompanied\tby\tosmolar\tdilution.\tThe\tincreased\tvolume\tof\tI...
[ 0.02651672065258026, -0.07211468368768692, 0.05233447998762131, -0.06853745877742767, -0.07782209664583206, -0.04172898828983307, 0.10079970955848694, 0.011050987988710403, 0.006782724522054195, 0.05868660286068916, 0.056819669902324677, -0.0767158791422844, 0.07677501440048218, 0.06875216...
the\tcells,\tparticularly\tthe\tbrain\tcells,\tto\tswell,\tleading\tto\theadache,\tnausea,\tvomiting,\tmuscle\ntwitching,\tblindness,\tand\tconvulsions\twith\timpending\tstupor.\tIf\tleft\n\tuntreated,\twater\tintoxication\tcan\nbe\tfatal.\tWater\tintoxication\tis\tnot\tcommonly\tseen\tin\tnormal,\thealthy\tindividuals...
[ 0.014653502963483334, -0.052376341074705124, 0.08210353553295135, -0.028076527640223503, -0.15532286465168, 0.004093681927770376, 0.12158776819705963, -0.025608308613300323, 0.01044565811753273, 0.03945133090019226, 0.09374027699232101, -0.071405328810215, 0.04266094043850899, 0.0099367592...
endurance\tathletes\twho\tconsume\tlarge\tamounts\tof\telectrolyte-free\tbeverages\tduring\tevents,\nindividuals\twith\tpsychiatric\tillness,\tor\tas\ta\tresult\tof\twater\tdrinking\tcontests\t(\nAdetoki\tet\tal,\t2013\n).\nFluid\toverload,\tor\t\nhypervolemia\n,\toccurs\twhen\texcess\tfluid\taccumulation\n\tis\tpresen...
[ -0.04030067101120949, -0.016977442428469658, 0.03155404329299927, 0.00373841798864305, -0.07622477412223816, 0.00039180804742500186, 0.08871554583311081, 0.00884655024856329, -0.030359575524926186, 0.01619500108063221, 0.06843076646327972, -0.03903040662407875, 0.03959766402840614, 0.04282...
,\toccurs\twhen\texcess\tfluid\taccumulation\n\tis\tpresent\twithin\tthe\nbody,\tleading\tto\texcess\tin\tcirculating\tblood\tvolume.\tThis\tmay\toccur\tas\ta\tresult\tof\texcess\tfluid\tintake\n(via\toral,\tenteral,\tor\tparenteral\troute),\tinjury\tor\tillness\tcausing\tstress\tto\tthe\tbody,\tor\tdiagnoses\tsuch
[ 0.012781702913343906, -0.04309966415166855, 0.0411190502345562, -0.04871951788663864, -0.11000826954841614, -0.016414424404501915, 0.0875730961561203, -0.0273455660790205, 0.027163784950971603, 0.054385460913181305, 0.07679250836372375, -0.027744358405470848, 0.07387173920869827, 0.0249022...
as\tkidney,\theart,\tor\tliver\tdisease.\tSymptoms\tof\tfluid\toverload\tmay\toften\tinclude\tgeneralized\tor\nlocalized\tswelling,\tsudden\tweight\tgain,\tdyspnea,\torthopnea,\tpulmonary\n\tcongestion,\tor\tmodifications\nin\tarterial\tpressures.\tTreatment\tfor\tfluid\toverload\tis\toften\tdictated\tby\tthe\tinherent...
[ -0.006513737142086029, -0.05421264097094536, -0.00009231371222995222, -0.007712069433182478, -0.07326972484588623, -0.03683643043041229, 0.04882531240582466, 0.03566733002662659, -0.00553441746160388, 0.0342545211315155, 0.05298836901783943, 0.03685913607478142, 0.06382723152637482, 0.0475...
may\tinclude\treduction\tin\tfluid\tintake,\tdiuretic\ttherapy,\tand\tsodium\trestriction.\nWater\telimination\nWater\tloss\tnormally\toccurs\tthrough\tthe\tkidneys\tas\turine\tand\tthrough\tthe\tGI\ttract\tin\tthe\tfeces\n(measurable,\t\nsensible\twater\tloss\n),\tas\twell\tas\tthrough\tair\texpired\tfrom\n\tthe\tlung...
[ 0.026677671819925308, -0.03222597390413284, 0.10145022720098495, -0.024420205503702164, -0.05721159279346466, -0.02615566924214363, 0.10038900375366211, 0.002904118737205863, -0.01039324700832367, 0.053742311894893646, 0.0693482831120491, -0.06439593434333801, 0.04785385727882385, 0.033483...
the\tlungs\tand\twater\tvapor\nlost\tthrough\tthe\tskin\t(nonmeasurable,\t\ninsensible\twater\tloss\n).\tThe\tkidney\tis\tthe\tprimary\tregulator\nof\tsensible\twater\tloss.\tUnder\tnormal\tconditions\tthe\tkidneys\thave\tthe\tability\tto\tadjust\tto\tchanges\tin\nbody\twater\tcomposition\tby\teither\tdecreasing\tor\ti...
[ 0.011452630162239075, -0.04730134829878807, 0.0905308723449707, -0.04200592264533043, -0.0984073281288147, -0.0052010370418429375, 0.07221215963363647, -0.022315971553325653, 0.020133215934038162, 0.03928695619106293, 0.05983596667647362, -0.06439575552940369, 0.060721058398485184, 0.04295...
are\tsubstances\tin\tthe\tdiet\tthat\tincrease\turinary\texcretion,\tsuch\tas\talcohol\n\tand\tcaffeine.\nInsensible\twater\tloss\tis\tcontinuous\tand\tusually\tunconscious.\tHigh\taltitude,\tlow\thumidity,\tand\thigh\ntemperatures\tcan\tincrease\tinsensible\tfluid\tloss\tthrough\tthe\tlungs\tand\tthrough\tsweat.\tAthl...
[ 0.04053368419408798, -0.016394704580307007, 0.11028550565242767, -0.023423753678798676, -0.06854617595672607, 0.00698655704036355, 0.1348665952682495, -0.045282863080501556, -0.04999847710132599, 0.049335651099681854, 0.040799371898174286, -0.07337930053472519, 0.03642326220870018, 0.02188...
lose\t6%\tto\t10%\tof\tbody\tweight\tin\tsweat\tloss\tand\tfluids\tneed\tto\tbe\treplaced.\tDehydration\tleads\tto\tan\nincrease\tin\tcore\tbody\ttemperature,\twhich\trises\t0.15\tto\t0.20°\tC\tfor\tevery\t1%\tof\tbody\n\tweight\tlost\tdue\nto\tsweating\t(\nCasa\tet\tal,\t2000\n).\tIn\thigh-risk\tconditions,\tit\tis\ts...
[ -0.0031167843844741583, 0.02194894105195999, 0.01857481338083744, 0.0712040588259697, -0.01992448978126049, 0.024874767288565636, 0.09708467125892639, 0.013896012678742409, -0.05597274377942085, -0.006848517805337906, 0.020290853455662727, -0.07866668701171875, 0.04197108745574951, -0.0181...
activity\tfluid\tloss\tand\tconsume\t1\tto\t1.25\tL\tof\tfluid\tfor\teach\t1\tkg\tof\tbody\twater\tlost\tduring\texercise\n(Binkley,\t2002).\nThe\tGI\ttract\tcan\tbe\ta\tmajor\tsource\tof\twater\tloss\t(\nFig.\t3.3\n).\tUnder\tnormal\tconditions\tthe\twater\ncontained\tin\tthe\t7\tto\t9\tL\tof\tdigestive\tjuices\tand\t...
[ 0.008343696594238281, -0.055952467024326324, 0.05117980018258095, 0.0043771653436124325, -0.09055683016777039, -0.014087450690567493, 0.07809261232614517, 0.007819240912795067, -0.007294727023690939, 0.01064245030283928, 0.06638770550489426, -0.05022558197379112, 0.039381977170705795, 0.05...
secreted\tdaily\tinto\tthe\tGI\ttract\tis\nreabsorbed\talmost\tentirely\tin\tthe\tileum\tand\tcolon,\texcept\tfor\tabout\t100\tmL\tthat\tis\texcreted\tin\tthe\nfeces.\tBecause\tthis\tvolume\tof\treabsorbed\tfluid\tis\tabout\ttwice\tthat\tof\tthe\tblood\tplasma,\texcessive\tGI\nfluid\tlosses\tthrough\tdiarrhea\tmay\thav...
[ 0.0143513735383749, -0.028999069705605507, 0.03626823052763939, -0.05480245500802994, -0.10211645066738129, 0.014135017059743404, 0.07504722476005554, -0.019488248974084854, -0.014187411405146122, 0.08330951631069183, 0.08972039073705673, -0.008353996090590954, 0.07152193784713745, 0.00167...
old\tindividuals.
[ 0.0038368389941751957, 0.02113982103765011, 0.036446843296289444, 0.017949333414435387, -0.0724538043141365, -0.006818681489676237, 0.12153884023427963, -0.017168954014778137, -0.04195452481508255, 0.015983927994966507, 0.05472828820347786, -0.06104840710759163, -0.036941275000572205, 0.03...
FIG.\t3.3\nContent\tof\tGastrointestinal\tSecretions\nCholeric\tdiarrhea,\tacute\tdiarrhea\tcaused\tby\tcontaminated\tfood\tor\twater\tcontaining\tthe\tbacteria\nvibrio\tcholera\n,\tis\tresponsible\tfor\tthe\tloss\tof\tmany\tlives\tin\tdeveloping\tcountries\tand\thydration\tcan\tbe\ncorrected\twithout\tintravenous\tflu...
[ -0.008400237187743187, -0.055723533034324646, 0.039462413638830185, -0.014300822280347347, -0.05130147561430931, 0.003977687563747168, 0.059091970324516296, 0.006035324186086655, -0.030111830681562424, 0.05701139569282532, 0.11379165202379227, -0.0707082599401474, 0.029375482350587845, 0.0...
of\twater,\tsugar,\tand\tsalt\tand\tis\thighly\teffective\n\tin\timproving\thydration\tstatus\t(\nParrish\tand\tDiBaise,\n2015\n).\tOther\tabnormal\tfluid\tlosses\tmay\toccur\tas\ta\tresult\tof\temesis,\themorrhage,\tfistula\tdrainage,\nburn\tand\twound\texudates,\tgastric\tand\tsurgical\ttube\tdrainage,\tand\tthe\tuse...
[ 0.03365778923034668, -0.044000715017318726, 0.07589559257030487, -0.019840307533740997, -0.06415858119726181, -0.004781982861459255, 0.08252154290676117, 0.007253851741552353, 0.008909718133509159, 0.05537331476807594, 0.06712022423744202, -0.04156047850847244, 0.0446723997592926, 0.038780...
When\twater\tintake\tis\tinsufficient\tor\twater\tloss\tis\texcessive,\thealthy\tkidneys\tcompensate\tby\nconserving\twater\tand\texcreting\tmore\tconcentrated\turine.\tThe\trenal\n\ttubules\tincrease\twater\nreabsorption\tin\tresponse\tto\tthe\thormonal\taction\tof\tvasopressin.\tHowever,\tthe\tconcentration\tof\tthe
[ 0.0001763900654623285, -0.05421934649348259, 0.08030100911855698, -0.07457622140645981, -0.0974724143743515, 0.014198112301528454, 0.08439435064792633, -0.03919427469372749, 0.02926540933549404, 0.035511862486600876, 0.05521214008331299, -0.11388183385133743, 0.055516671389341354, 0.047934...
urine\tmade\tby\tthe\tkidneys\thas\ta\tlimit:\tapproximately\t1400\tmOsm/L.\tOnce\tthis\tlimit\thas\tbeen\nreached,\tthe\tbody\tloses\tits\tability\tto\texcrete\tsolutes.\tThe\tability\tof\tthe\tkidneys\tto\tconcentrate\turine\nmay\tbe\tcompromised\tin\tolder\tindividuals\tor\tin\tyoung\tinfants,\tresulting\tin\tincrea...
[ -0.013519207946956158, -0.04901113361120224, 0.09465786069631577, -0.06036614254117012, -0.11863123625516891, -0.047841425985097885, 0.09151209890842438, 0.0018173462012782693, -0.027294743806123734, 0.05705209821462631, 0.04794051870703697, -0.035599235445261, 0.06337903439998627, 0.03279...
risk\tof\ndeveloping\tdehydration\tor\thypernatremia,\tespecially\tduring\tillness.\nSigns\tof\tdehydration\tinclude\theadache,\tfatigue,\tdecreased\tappetite,\tlightheadedness,\tpoor\tskin\nturgor\t(although\tthis\tmay\tbe\tpresent\tin\twell-hydrated\tolder\tpersons),\tskin\ttenting\ton\tthe\tforearm,
[ 0.03965719789266586, -0.013063945807516575, 0.02920818328857422, -0.009577806107699871, -0.008761872537434101, 0.0588616244494915, 0.10020124912261963, 0.006322910543531179, 0.01974382810294628, 0.03248521685600281, 0.09514684230089188, -0.06831855326890945, 0.07279018312692642, 0.00785715...
concentrated\turine,\tdecreased\turine\toutput,\tsunken\teyes,\tdry\tmucous\tmembranes\tof\tthe\tmouth\tand\nnose,\torthostatic\tblood\tpressure\n\tchanges,\tand\ttachycardia.\tIn\ta\tdehydrated\tperson\tthe\tspecific\ngravity,\ta\tmeasure\tof\tthe\tdissolved\tsolutes\tin\turine,\tincreases\tabove\tthe\tnormal\tlevels,...
[ -0.006785609759390354, -0.05880105867981911, 0.07542914897203445, -0.004124662838876247, -0.1282171607017517, 0.00854011531919241, 0.12571343779563904, 0.02050069347023964, 0.0011282955529168248, 0.03386890888214111, 0.04886035993695259, -0.1033046767115593, 0.05090823024511337, 0.03324107...
becomes\tremarkably\tdarker.\nHigh\tambient\ttemperature\tand\tdehydration\tadversely\taffect\texercise\tperformance.\tFluids\tof\nappropriate\tcomposition\tin\tappropriate\tamounts\tare\tessential\t(see\t\nClinical\tInsight\n:\tWater\nRequirements:\tWhen\tEight\tIs\tNot\tEnough\n).\nClinical\tassessment\tof\tfluid\tst...
[ 0.013260986655950546, -0.07093140482902527, 0.07368390262126923, -0.03533554449677467, -0.08332223445177078, -0.016501467674970627, 0.09775795042514801, 0.009844249114394188, 0.002540143672376871, 0.06132209673523903, 0.07084032148122787, -0.04981089010834694, 0.038902901113033295, 0.06351...
).\nClinical\tassessment\tof\tfluid\tstatus\nA\tvariety\tof\tmethods\tto\testimate\tfluid\trequirements\tare\tbased\ton\tage,\tcaloric\tintake,\tand\tweight.\nObesity\thas\tled\tto\tchallenges\twith\tusing\tweight-based\tcalculations\tfor\tfluid\trequirements,\tas\twater\naccounts\tfor\tonly\t45%\tto\t55%\tof\tbody\twe...
[ -0.010825465433299541, 0.018596744164824486, 0.009775415994226933, -0.010689081624150276, -0.0848567858338356, -0.05545545741915703, 0.07857946306467056, 0.023907119408249855, -0.0036514413077384233, -0.007979299873113632, 0.05870160087943077, -0.07944206893444061, 0.06385685503482819, 0.0...
In\tclinical\tpractice,\tfluid\testimations\tshould\tbe\tindividualized\n\tto\teach\tpatient,\tespecially\tthose\twith\ncardiac,\tliver,\tor\trenal\tfailure,\tand\tin\tthe\tpresence\tof\tongoing\thigh-volume\tGI\tlosses.\nIn\tmost\tcases\ta\tsuitable\tdaily\twater\tintake\t(fluids\tand\tincluding\tfoods)\tis\tapproxima...
[ -0.014529846608638763, -0.046755217015743256, 0.05354040116071701, -0.05665199086070061, -0.0666169673204422, -0.0505046583712101, 0.09321136027574539, 0.09233509004116058, 0.024889348074793816, 0.00023373997828457505, 0.05337781459093094, -0.04122294485569, 0.0465717539191246, 0.093110896...
cups)\tfor\tadult\tmales\tand\t2.7\tL\t(11+\tcups)\tfor\tadult\tfemales,\tdepending\ton\tbody\tsize\t(\nInstitute\tof\nMedicine\tof\tthe\tNational\tAcademies,\t2005\n).\tBecause\tsolid\tfood\tprovides\n\t19%\tof\ttotal\tdaily\tfluid\nintake,\tthis\tequals\t750\tmL\tof\twater\tor\tapproximately\t3\tcups\tdaily.\tWhen\tt...
[ -0.024318834766745567, -0.021182172000408173, 0.021618572995066643, -0.0497187115252018, -0.07600918412208557, -0.02157250978052616, 0.07129966467618942, 0.05301874503493309, -0.029000118374824524, -0.025802133604884148, 0.019642723724246025, -0.0950455442070961, 0.03986851125955582, 0.027...
300\tmL\t(about\t1\tcup)\tof\twater\tcontributed\tby\toxidative\tmetabolism,\tmen\tshould\tconsume\tabout\t11.5\ncups\tand\twomen\tneed\t7\tcups\tof\tfluids\tdaily.\tTotal\tfluid\tintake\tcomes\tfrom\tdrinking\twater,\tother\nliquids,\tand\tfood;\tthe\tadequate\tintake\t(AI)\tfor\twater\tis\tfor\ttotal\tdaily\twater\n\...
[ -0.030249422416090965, -0.02785339020192623, 0.02073032222688198, -0.0831422433257103, -0.06590518355369568, -0.048041943460702896, 0.08325102925300598, 0.017383839935064316, -0.01813291572034359, 0.01864675059914589, 0.033105652779340744, -0.08842688798904419, 0.06240783631801605, 0.01450...
intake\tand\tincludes\tall\ndietary\twater\tsources.\nUnfortunately\tthere\tis\tno\tgold\tstandard\tto\tassess\thydration\tstatus.\tClinicians\tmust\tcarefully\tassess
[ 0.04183625429868698, -0.017042899504303932, 0.09898524731397629, -0.005931631661951542, -0.05023575574159622, 0.002260875655338168, 0.11101709306240082, -0.03308941796422005, -0.03166910260915756, -0.00031408952781930566, 0.06829914450645447, -0.11452943086624146, 0.006298667751252651, 0.0...
data\tfrom\ta\tvariety\tof\tsources,\tincluding\tphysical\texamination\tby\tthe\tmedical\tteam,\tnutrition-focused\nphysical\texaminations,\timaging\treports\t(e.g.,\tidentifying\tabnormal\tfluid\tcollections\twithin\tthe\tlungs,\nascites),\tlaboratory\tstudies\t(i.e.,\tserum\n\tsodium),\tsubjective\treport\tof\tsympto...
[ 0.03886794671416283, -0.04067915678024292, 0.012795002199709415, -0.02421986311674118, -0.08699004352092743, -0.055263686925172806, 0.053532835096120834, 0.05917166545987129, 0.003222155850380659, -0.002666961867362261, 0.051902689039707184, -0.04031916707754135, 0.06449035555124283, 0.020...
sodium),\tsubjective\treport\tof\tsymptoms\tfrom\tpatients,\nsudden\tweight\tchanges,\tmedications,\tand\tvital\tsigns.\tIn\tclinical\tsettings\tit\tis\timportant\tto\nacknowledge\tall\tsources\tof\tfluid\tdelivery\t(oral,\tenteral\tfeeding\ttube,\tintravenous\tfluids,\tparenteral\nnutrition,\tand\tintravenous\tfluids\...
[ 0.013226766139268875, -0.061774611473083496, 0.055558059364557266, -0.011280550621449947, -0.08244984596967697, -0.01225682720541954, 0.08594338595867157, 0.06494423747062683, -0.05373522266745567, -0.009797616861760616, 0.05765984207391739, -0.04507333040237427, 0.0715876892209053, 0.0578...
urine,\tdiuretic\tmedications,\tand\tGI\tsecretions\t(e.g.,\n\temesis,\tgastric\tsecretions,\tsurgical\tdrains,\tstool,\nfistulas)\t(\nPopkin\tet\tal,\t2010\n).\nOf\tnote,\tthirst\tis\tnot\tan\teffective\tsignal\tto\tconsume\tfluids\tin\tinfants,\theavily\texercising\tathletes\n(\nCasa,\t2015\n),\tindividuals\tin\textr...
[ -0.026252105832099915, -0.008913435973227024, 0.08653341978788376, -0.034195248037576675, -0.08244036138057709, -0.014062060974538326, 0.09283099323511124, 0.02023094892501831, -0.01750781387090683, 0.026243366301059723, 0.06184826046228409, -0.04501538351178169, 0.03281916677951813, 0.028...
diminished\tthirst\tsensation.\tHospitalized\tpatients,\tregardless\tof\tthe\tdiagnosis,\tare\tat\trisk\tfor\twater\nand\telectrolyte\n\timbalance.\tOlder\tadults\tare\tparticularly\tsusceptible\tbecause\tof\tfactors\tsuch\tas\nimpaired\trenal\tconcentrating\tability,\tfever,\tdiarrhea,\tvomiting,\tand\ta\tdecreased\ta...
[ 0.023653024807572365, -0.06923601776361465, 0.07021595537662506, -0.02811046689748764, -0.10934992879629135, -0.034993913024663925, 0.07996337115764618, 0.09341824799776077, -0.009979834780097008, 0.023258216679096222, 0.07493570446968079, -0.01621304266154766, 0.049608029425144196, 0.0336...
themselves.\nCLINICAL\tINSIGHT\nWater\tRequirements:\tWhen\tEight\tIs\tNot\tEnough\nThere\tis\tno\tstorage\tform\tof\twater,\tand\ttherefore\tfluid\trequirements\tand\tfluid\tlosses\tmust\tbe\nmaintained\tat\tequilibrium.\tOften\tclinicians\n\tquickly\testimate\tfluid\trequirements\tbased\ton\tenergy
[ 0.0338057205080986, -0.055885668843984604, 0.05020802840590477, -0.040356896817684174, -0.1051277220249176, -0.026507394388318062, 0.11542476713657379, 0.017213884741067886, -0.004925553221255541, 0.056093502789735794, 0.06372543424367905, -0.08074561506509781, 0.01765931025147438, 0.04086...
quickly\testimate\tfluid\trequirements\tbased\ton\tenergy\nrequirements\t(1\tmL/kcal\tfor\tadults\tand\t1.5\tmL/kcal\tfor\tinfants)\tor\tapproximately\t35\tmL/kg\tof\nusual\tbody\tweight\tin\tnonobese\tadults,\t50\tto\t60\tmL/kg\tin\tchildren,\tand\t150\tmL/kg\tin\tinfants.\nAt\tcertain\tpoints\twithin\tthe\tlifecycle,...
[ -0.04738878086209297, -0.01593257300555706, 0.026095235720276833, -0.015809878706932068, -0.08765166997909546, -0.02860930934548378, 0.09348690509796143, 0.03602068871259689, -0.024551905691623688, 0.0110893240198493, 0.09541117399930954, -0.10919550806283951, 0.033077094703912735, -0.0073...
more\twater\tbecause\tof\tthe\tlimited\tcapacity\tof\tthe\tkidneys\tto\n\thandle\ta\tlarge\trenal\tsolute\tload,\nhigher\tpercentage\tof\tbody\twater,\tand\tlarge\tsurface\tarea\tper\tunit\tof\tbody\tweight.\tA\tlactating\nwoman’s\tneed\tfor\twater\talso\tincreases,\tapproximately\t2\t½\tto\t3\tcups\tper\tday\tfor\tmil...
[ -0.011344618164002895, -0.07122597843408585, 0.056023988872766495, -0.05843670293688774, -0.0647604838013649, -0.0221933014690876, 0.07183732092380524, -0.011935251764953136, -0.020059335976839066, 0.046670544892549515, 0.05105596035718918, -0.0741528570652008, 0.06440973281860352, 0.02420...
Knowledge\tof\tdisease\tstates\talso\thelps\tin\tdetermining\twhen\thigher\tfluid\trequirements\tmay\noccur.\tFluid\tintake\tshould\texceed\tthe\texcretion\tof\tsensible\tand\tinsensible\tlosses\tin\n\torder\tto\nprevent\tdehydration.\tIn\tpatients\twith\tShort\tBowel\tSyndrome\t(SBS),\tinadequate\tabsorption\tof
[ 0.02709820307791233, -0.02310100756585598, 0.013445225544273853, -0.01917997933924198, -0.0932220071554184, -0.018441850319504738, 0.11860600858926773, 0.0031156749464571476, -0.02370251715183258, 0.0583341084420681, 0.08187668025493622, -0.02075362764298916, 0.07423999905586243, 0.0521957...
fluid\tcan\tlead\tto\tdehydration.\tSBS\tpatients\twith\tan\tenterostomy\t(or\tcolon\tnot\tconnected\tto\tthe\nsmall\tbowel)\toften\thave\tincreased\tfluid\trequirements\tand\tare\tat\tan\tincreased\trisk\tof\tdehydration\nif\ttoo\tmuch\tstool\tis\tlost\tdue\tto\tmalabsorption.\tLike\tchildren\twith\tinfectious\tdiarrh...
[ 0.010884935036301613, -0.03296082839369774, 0.08271545171737671, -0.010615861043334007, -0.0651993528008461, -0.014187374152243137, 0.16622187197208405, 0.02733655832707882, 0.003854513866826892, 0.008647403679788113, 0.08320987224578857, -0.04314824193716049, 0.033837493509054184, 0.07645...
countries,\n\tSBS\tpatients\tbenefit\tfrom\tthe\tuse\tof\toral\trehydration\tsolutions\tby\tmouth,\tin\torder\tto\nutilize\tthe\tactive\tco-transport\tof\tsodium\tand\tglucose\tmolecules\tat\tthe\tintestinal\tbrush\tborder,\nwhich\thelps\tmaintain\thydration\t(Matarese,\t2005).\tUse\tof\toral\trehydration\tsolution\tsi...
[ 0.03054691106081009, -0.05929378792643547, 0.06439831107854843, -0.017219990491867065, -0.06577212363481522, 0.015398195013403893, 0.08766795694828033, -0.009771540760993958, -0.002995146904140711, 0.058742981404066086, 0.10496781021356583, -0.04425353184342384, 0.010074792429804802, 0.052...
throughout\tthe\tday\tand\tseparating\tfluids\tfrom\tmeals\tcan\tbe\thelpful\tstrategies\tfor\thelping\tSBS\npatients\tmaintain\ttheir\thydration\n\tstatus.\tWhen\toral\tintake\talone\tis\tnot\tsufficient\tto\tprevent\ndehydration,\tparenteral\tfluids\tmay\tbe\tneeded.\tUse\tof\tparental\tfluids\tcan\tbe\ttemporary\t(e...
[ 0.007081399671733379, -0.026873214170336723, 0.06047207862138748, -0.030472850427031517, -0.03878055512905121, -0.04565102979540825, 0.06445101648569107, -0.004325222689658403, -0.0027163780760020018, 0.0353664830327034, 0.0750809982419014, -0.037775635719299316, 0.03493529558181763, 0.023...
to\tan\tacute\tevent\tsuch\tas\ta\turinary\ttract\tinfection\tin\tan\telderly\tadult)\tor\tchronic\tfor\tcertain\ndisease\tstates\t(e.g.,\tSBS\tor\tgastrointestinal\tfistula).\nFluid\tneeds\tof\thospitalized\tpatients\tshould\tbe\tindividualized\tand\tadequacy\tof\tfluid\tintake\nassessed\tfrom\tphysical\texamination\t...
[ 0.005283458158373833, -0.03492668271064758, 0.06649307161569595, -0.029326310381293297, -0.10937543213367462, -0.011997053399682045, 0.10708945989608765, 0.02920728363096714, -0.019382689148187637, 0.02419036068022251, 0.07765810936689377, -0.025292765349149704, 0.0501277856528759, 0.05994...
imaging\treports,\tlaboratory\tstudies\t(Na,\tBUN,\tCr,\tHgb/Hct,\talbumin,\tetc.),\tsubjective\treport\tof\nsymptoms\tfrom\tpatients,\tsudden\tweight\tchanges,\tmedications,\tand\tvital\tsigns.\nElectrolytes\nElectrolytes\n\tare\tminerals\twith\telectric\tcharges\tthat\tdissociate\tin\ta\tsolution\tinto\tpositive\tor\...
[ 0.028806794434785843, -0.0634554848074913, 0.01651899330317974, -0.06208765134215355, -0.07765676081180573, -0.050254371017217636, 0.09878730028867722, 0.08984176814556122, 0.01462159026414156, 0.03153616189956665, 0.09429508447647095, -0.021431664004921913, 0.06860878318548203, 0.07281798...
negatively\n\tcharged\tions.\tElectrolytes\tcan\tbe\tsimple\tinorganic\tsalts\tof\tsodium,\tpotassium,\tor\nmagnesium,\tor\tcomplex\torganic\tmolecules;\tthey\tplay\ta\tkey\trole\tin\ta\thost\tof\tnormal\tmetabolic\nfunctions\t(\nTable\t3.4\n).\tOne\tmilliequivalent\t(mEq)\tof\tany\tsubstance\thas\tthe\tcapacity\tto\tc...
[ -0.033031076192855835, -0.05939001590013504, 0.008465389721095562, -0.021265773102641106, -0.09120778739452362, -0.03480546921491623, 0.10962534695863724, 0.03546597808599472, 0.03372002765536308, 0.05594291910529137, 0.11014746129512787, -0.04268175736069679, 0.045368824154138565, 0.07257...
chemically\twith\t1\tmEq\tof\ta\tsubstance\twith\tan\topposite\tcharge.\tFor\tunivalent\tions\t(e.g.,\tNa\n+\n),\t1\nmillimole\t(mmol)\tequals\t1\tmEq;\tfor\n\tdivalent\tions\t(e.g.,\tCa\n++\n),\t1\tmmol\tequals\t2\tmEq\t(see\t\nAppendix\t1\nfor\tconversion\tguidelines).\nTABLE\t3.4\nElectrolyte\tClassification\nElectr...
[ -0.034705135971307755, -0.06876201182603836, 0.01582079939544201, -0.021377375349402428, -0.03772968798875809, -0.00423551956191659, 0.059982359409332275, 0.059838179498910904, -0.01835133507847786, 0.028309661895036697, 0.059009991586208344, -0.03486735373735428, 0.06548744440078735, 0.09...
Electrolyte\nLocation\nCations\nSodium\nExtracellular\tcation\nPotassium\nIntracellular\tcation\nCalcium\nExtracellular\tcation\nMagnesium\nIntracellular\tcation\nAnions\nChloride\nExtracellular\tAnion\nCO\n2\nExtracellular\tAnion\nPhosphorus\t(inorganic)\nIntracellular\n\tAnion\nThe\tmajor\t\nextracellular
[ -0.028223786503076553, -0.08203227818012238, 0.005092157516628504, 0.010303954593837261, -0.038328174501657486, -0.03321053460240364, 0.10183081030845642, 0.011330767534673214, -0.01779099740087986, 0.06520704180002213, 0.056671760976314545, -0.061831917613744736, 0.016422703862190247, 0.0...
Phosphorus\t(inorganic)\nIntracellular\n\tAnion\nThe\tmajor\t\nextracellular\n\telectrolytes\tare\tsodium,\tcalcium,\tchloride,\tand\tbicarbonate.\tPotassium,
[ -0.0326976515352726, -0.07054838538169861, 0.05055711418390274, -0.011389432474970818, -0.018010137602686882, -0.03908470645546913, 0.1355603039264679, 0.0031835264526307583, 0.015490485355257988, 0.05734427273273468, 0.030223242938518524, -0.072707898914814, -0.01778864674270153, 0.062934...
magnesium,\tand\tphosphate\tare\tthe\tmajor\t\nintracellular\n\telectrolytes.\tThese\telements,\twhich\texist\tas\nions\tin\tbody\tfluids,\tare\tdistributed\tthroughout\tall\tbody\tfluids.\tElectrolytes\tare\tresponsible\tfor\nmaintenance\tof\tphysiologic\tbody\tfunctions,\tcellular\tmetabolism,\tneuromuscular\tfunctio...
[ -0.060230132192373276, -0.07063324004411697, 0.06336846202611923, -0.022617820650339127, -0.067771315574646, -0.05884584039449692, 0.14336661994457245, 0.06191639602184296, -0.03784951940178871, 0.05993462726473808, 0.0697842463850975, -0.0170931164175272, 0.03607477620244026, 0.0276569705...
osmotic\n\tequilibrium.\tAlthough\toral\tintake\tvaries,\thomeostatic\tmechanisms\tregulate\tthe\nconcentrations\tof\telectrolytes\tthroughout\tthe\tbody.\nChanges\tin\teither\tintracellular\tor\textracellular\telectrolyte\tconcentrations\tcan\thave\ta\tmajor\timpact\non\tbodily\tfunctions.\tThe\t\nNa/K-ATPase\tpump\n\...
[ -0.0085670854896307, -0.11001380532979965, 0.04733998700976372, -0.056567344814538956, -0.1412891447544098, -0.0269324891269207, 0.07194583117961884, 0.030393436551094055, 0.008681069128215313, 0.09766411781311035, 0.10664522647857666, -0.04924721270799637, 0.028207549825310707, 0.08099135...
Na/K-ATPase\tpump\n\tclosely\tregulates\tcellular\telectrolyte\tcontents\tby\nactively\tpumping\tsodium\tout\tof\tcells\tin\texchange\tfor\tpotassium.\tOther\telectrolytes\n\tfollow\tion\ngradients\t(gradient\tof\telectrical\tpotential\tfor\tmovement\tacross\ta\tmembrane).\nCalcium\nAlthough\tapproximately\t99%\tof\tth...
[ -0.061492156237363815, -0.07582639902830124, 0.01966278627514839, -0.0508289597928524, -0.09668375551700592, -0.03748165816068649, 0.11348798125982285, 0.034483637660741806, 0.003631330793723464, 0.0222320593893528, 0.06798293441534042, -0.08622562140226364, 0.0565209835767746, 0.088527135...
Calcium\nAlthough\tapproximately\t99%\tof\tthe\tbody’s\tcalcium\t(Ca\n++\n)\tis\tstored\tin\tthe\tskeleton\t(bones\tand\tteeth),\nthe\tremaining\t1%\thas\timportant\tphysiologic\tfunctions.\tIonized\tCa\n++\n\twithin\tthe\tvascular\ncompartment\tis\ta\tcation\twith\ta\tpositive\tcharge.\tApproximately\thalf\tof\tthe\tC...
[ -0.009290515445172787, -0.0898139476776123, 0.07385929673910141, 0.005003892816603184, -0.12442853301763535, -0.023477843031287193, 0.06722410768270493, 0.04787874594330788, -0.02951926738023758, 0.08722995221614838, 0.04689428582787514, -0.04373892396688461, 0.025095665827393532, 0.059538...
++\n\tfound\tin\tthe\nintravascular\tcompartment\n\tis\tbound\tto\tthe\tserum\tprotein\talbumin.\tThus,\twhen\tserum\talbumin\tlevels\nare\tlow,\ttotal\tCa\n++\n\tlevels\tdecrease\tbecause\tof\thypoalbuminemia.\nThe\tbinding\tability\tof\tCa\n++\n\tand\tits\tionized\tcontent\tin\tblood\thave\timplications\tfor\tnormal\...
[ -0.02330126240849495, -0.0736217126250267, 0.03371420130133629, -0.011156938970088959, -0.06906580924987793, 0.055268704891204834, 0.0750126764178276, 0.03732220456004143, -0.017985736951231956, 0.07877431809902191, 0.07652407139539719, -0.00836092047393322, 0.04243776574730873, 0.04289707...
homeostatic\tmechanisms.\tBlood\ttests\tfor\tCa\n++\n\tlevels\toften\tmeasure\ttotal\tand\tionized\tCa\n++\n\tlevels.\nIonized\t(or\tfree,\tunbound)\tCa\n++\n\tis\tthe\tactive\tform\tof\tCa\n++\n\tand\tis\tnot\timpacted\n\tby\thypoalbuminemia.\nIn\thealthy\tadults,\tnormal\tlevels\tfor\tserum\ttotal\tCa\n++\n\tare\tabo...
[ -0.03997817635536194, -0.06306727975606918, 0.03702394291758537, 0.0005444457638077438, -0.03885263577103615, 0.02991206757724285, 0.05876820161938667, 0.08413491398096085, 0.0025140116922557354, 0.0544523224234581, 0.04960973560810089, -0.0416858047246933, 0.08196702599525452, 0.031383123...
are\tabout\t8.5\tto\t10.5\tmg/dL,\twhereas\tnormal\nlevels\tfor\tionized\tCa\n++\n\tare\t4.5\tto\t5.5\tmEq/L\t(refer\tto\tthe\treference\tranges\tfor\teach\treporting\nlaboratory).\nFunctions\nCa\n++\n\tis\tan\textracellular\tcation\tnecessary\tfor\tblood\tclotting;\tCa\n++\n\tregulates\tnerve\ttransmission,\nmuscle\tc...
[ -0.011128191836178303, -0.053438812494277954, 0.004192296415567398, -0.06225791200995445, -0.06977114081382751, -0.00035822679637931287, 0.09860648214817047, 0.05845971778035164, 0.005847369786351919, 0.0620250403881073, 0.08319278806447983, -0.015079928562045097, 0.04360412061214447, 0.06...
Ca\n++\n\tis\tregulated\tby\nparathyroid\thormone\t(PTH),\tcalcitonin,\tvitamin\tD,\tand\tphosphorus.\tThrough\ta\tcomplex\tsystem\tof\nregulation\tamong\tmultiple\torgans,\tincluding\tthe\tkidney,\tGI\ttract,\tand\tbone,\tCa\n++\n\tabsorption\tcan\tbe\nenhanced\tto\tincrease\tCa\n++\n\treabsorption\tto\tmaintain\thome...
[ -0.032873429358005524, -0.06046929955482483, 0.008636935614049435, -0.08120615780353546, -0.12871479988098145, 0.027309473603963852, 0.09858991205692291, 0.029348863288760185, 0.012512002140283585, 0.0806407555937767, 0.08873192965984344, -0.06108657643198967, 0.07796193659305573, 0.058143...
++\n\tlevels\tare\tlow,\nPTH\tcauses\trelease\tof\tCa\n++\n\tfrom\tthe\tbones\tand\tstimulates\tincreased\tabsorption\tfrom\tthe\n\tGI\ttract.\nCalcitonin\tworks\tin\tthe\topposite\tdirection,\tshutting\toff\tthe\trelease\tof\tCa\n++\n\tfrom\tthe\tbone\tand\ndecreasing\tGI\tabsorption.\tVitamin\tD\tstimulates\twhile\tp...
[ -0.024767238646745682, -0.07172524929046631, 0.013284607790410519, -0.0377621129155159, -0.1028623878955841, 0.002695924136787653, 0.11531449854373932, 0.019102459773421288, -0.011529072187840939, 0.06424357742071152, 0.07441031187772751, -0.03640877455472946, 0.06633647531270981, 0.028895...
++\n\tabsorption\tin\tthe\tGI\ntract.\nIn\tthe\tsetting\tof\thypoalbuminemia,\tserum\tCa\n++\n\tlevels\tare\tnot\taccurate\tbecause\tnearly\t50%\tof\nCa\n++\n\tis\tprotein\tbound.\tAn\tionized\tCa\n++\n\tlevel\tis\tthe\tmost\taccurate\tassay\tfor\tCa\n++\n\tbecause\tit\n\tis\tthe\nactive\tform\tand\tis\tnot\taffected\t...
[ -0.0145639106631279, -0.049664825201034546, 0.017080161720514297, -0.03418055176734924, -0.056448161602020264, 0.038005392998456955, 0.10401634871959686, 0.021551886573433876, -0.01690502092242241, 0.07916194945573807, 0.08293171226978302, -0.06320340931415558, 0.050930071622133255, 0.0345...
Ca\n++\n\tare\tapproximately\t8.5\tto\t10.5\tmg/dL,\twhereas\tnormal\tlevels\tfor\tionized\tCa\n++\n\tare\t4.5\tto\t5.5\nmEq/L\t(refer\tto\tthe\treference\tranges\tfor\teach\treporting\tlaboratory).\tWhen\tionized\tCa\n++\n\tlevels\tare\nnot\tavailable,\ta\tsimple\tformula\tmay\tbe\tused.\tThe\t\ncorrected\tcalcium\n\t...
[ -0.023583512753248215, -0.014694268815219402, 0.037359997630119324, -0.046310678124427795, -0.0967007651925087, 0.024729689583182335, 0.049180395901203156, 0.031831398606300354, 0.05468582361936569, 0.05330132320523262, 0.11412253230810165, -0.054890137165784836, 0.05253357067704201, 0.063...
formula\taccounts\tfor\ta\t0.8\nmg/dL\n\tdecrease\tin\tCa\n++\n\tfor\teach\t1\tg/dL\tdecrease\tin\tserum\talbumin\tbelow\t4\tg/dL.\tThe\tcorrected\ncalcium\tformula\tis\nIonized\tCa\n++\n\tlevels\tare\taltered\tinversely\tby\tchanges\tin\tacid–base\tbalance;\tas\tserum\tpH\trises,\tCa\n++\nbinds\twith\tprotein,\n\tlead...
[ 0.014514717273414135, -0.05022601783275604, 0.007657921873033047, -0.07784850895404816, -0.1021629050374031, 0.02155439183115959, -0.010391337797045708, 0.07197821885347366, 0.02917191945016384, 0.06456992030143738, 0.07836832851171494, -0.041480716317892075, 0.06161797419190407, 0.0532672...
++\n\tlevels.\tAs\tpH\tis\tlowered,\tthe\topposite\toccurs.\nBecause\tCa\n++\n\thas\tan\timportant\trole\tin\tcardiac,\tnervous\tsystem,\tand\tskeletal\tmuscle\tfunction,\nhypocalcemia\tand\thypercalcemia\tcan\tbecome\tlife\tthreatening.\nCommon\tcauses\tof\thypercalcemia\tare\tcancer\twith\tthe\tpresence\tof\tbone\tme...
[ -0.010266191326081753, -0.005873564165085554, 0.05721888691186905, 0.007770197466015816, -0.02951405756175518, 0.04951857030391693, 0.10237251967191696, 0.014481228776276112, -0.01902184821665287, 0.0668809711933136, 0.09809774160385132, -0.03913314640522003, 0.06421864777803421, 0.0065776...
hyperparathyroidism,\twhen\tthere\tis\ta\tlarge\tamount\tof\tCa\n++\n\tmoved\tinto\tthe\tECF.\tSymptoms\n\tof\nhypercalcemia\tinclude\tlethargy,\tnausea,\tvomiting,\tmuscle\tweakness,\tand\tdepression.\tTreatment\nusually\tis\tdirected\tat\ttreating\tthe\tunderlying\tcause\tof\tthe\tproblem,\tdiscontinuing\tCa\n++\n-co...
[ 0.029933592304587364, -0.01633116975426674, 0.03997237607836723, -0.034778811037540436, -0.07539136707782745, 0.01354845892637968, 0.08715564757585526, 0.030535243451595306, -0.011818615719676018, 0.06139005720615387, 0.10834600776433945, -0.007972911931574345, 0.08522850275039673, 0.02054...
++\n-containing\nmedications,\tand\tincreasing\tthe\texcretion\tof\tCa\n++\n\tthough\tthe\tkidneys\t(by\tdelivery\tof\tintravenous\nfluids\tfollowed\tby\tdiuretic\tmedications).\nHypocalcemia\toften\tis\tmarked\twith\tnumbness\tor\ttingling,\thyperactive\n\treflexes,\ttetany,\tlethargy,\nmuscle\tweakness,\tconfusion,\t...
[ -0.012050872668623924, -0.010456954129040241, 0.027325231581926346, 0.0048974500969052315, -0.03924168646335602, 0.03890262916684151, 0.09577581286430359, 0.026203392073512077, -0.020099615678191185, 0.037944450974464417, 0.09169989079236984, 0.0209368709474802, 0.07318514585494995, 0.0115...
magnesium\tlevels,\tmedications\tthat\tcause\tCa\n++\n\tlosses,\thypoalbuminemia,\tvitamin\tD\tdeficiency,\tor\nhypoparathyroidism.\tOral\tCa\n++\n\tsupplements\tare\tmost\toften\tthe\tfirst-line\ttherapy\tin\tthe\tabsence\tof\nsymptoms.\tBecause\tother\thormones,\telectrolytes,\tand\tvitamins\tare\tinvolved\tin\tCa\n+...
[ -0.06365758925676346, -0.07545417547225952, 0.04639299586415291, 0.015667926520109177, -0.04254062473773956, 0.02105092629790306, 0.10941044986248016, 0.059878986328840256, -0.06206928938627243, 0.06789008527994156, 0.06545081734657288, 0.006305854767560959, 0.07483011484146118, 0.01867078...
++\n\tregulation,\nthese\tare\tassessed\tin\tthe\tsetting\tof\ttrue\thypocalcemia.\tLow\tphosphorus\tand\tmagnesium\tlevels\tmust\nbe\treplete\tbefore\tCa\n++\n\tlevels\tcan\tbe\tcorrected\t(\nRhoda\tet\tal,\t2011\n).\nAbsorption\tand\texcretion\nApproximately\t20%\tto\t60%\tof\tdietary\tCa\n++\n\tis\tabsorbed\tand\tis...
[ -0.030574515461921692, -0.05805625766515732, 0.022692915052175522, -0.018807746469974518, -0.07296614348888397, 0.01815871149301529, 0.1275636851787567, 0.03623698279261589, -0.01463338453322649, 0.05704852193593979, 0.06364665180444717, -0.020443160086870193, 0.05465492233633995, 0.041467...
to\tmaintain\tsteady\tserum\tCa\n++\n\tlevels\tin\tthe\tface\tof\tfluctuating\tintake.\tThe\tileum\tis\tthe\tmost\nimportant\tsite\tof\tCa\n++\n\tabsorption.\tCa\n++\n\tis\tabsorbed\tvia\tpassive\ttransport\tand\tthrough\ta\tvitamin\tD–\nregulated\ttransport\tsystem.\nThe\tkidney\tis\tthe\tmain\tsite\tof\tCa\n++\n\texc...
[ 0.006892758887261152, -0.054251957684755325, 0.016699008643627167, -0.08977408707141876, -0.11364518105983734, 0.027180597186088562, 0.09033630043268204, -0.010757886804640293, -0.013279463164508343, 0.09733837097883224, 0.05606265738606453, -0.021826257929205894, 0.06174437329173088, 0.04...
++\n\texcretion.\tThe\tmajority\tof\tserum\tCa\n++\n\tis\tbound\tto\tproteins\tand\nnot\tfiltered\tby\tthe\tkidneys;\tonly\tabout\t100\tto\t200\tmg/day\tis\texcreted\tin\tthe\turine\tin\tnormal\tadults.\nCa\n++\n\tis\talso\texcreted\tthrough\tsweat\tand\tfeces.
[ -0.008475024253129959, -0.012536143884062767, 0.0775991901755333, -0.031310755759477615, -0.1196470707654953, 0.07569758594036102, 0.1591121107339859, -0.015159478411078453, -0.013227970339357853, 0.046067748218774796, 0.0765821635723114, -0.06543320417404175, 0.04759935662150383, 0.004877...
Sources\nDairy\tproducts\n\tare\tthe\tmain\tsource\tof\tCa\n++\n\tin\tthe\tAmerican\tdiet,\twith\tsome\tgreen\tvegetables,\tnuts,\nlegumes,\tcanned\tfish\tincluding\tbones,\tand\tCa\n++\n-enriched\ttofu\thaving\tmoderate\tamounts\tof\tCa\n++\n.\nFood\tmanufacturers\tfortify\tmany\tfoods\twith\tadditional\tCa\n++\n,\tsu...
[ -0.08225852996110916, -0.007622762583196163, -0.02265273593366146, 0.005169624462723732, -0.02839037962257862, 0.02798551507294178, 0.05005543678998947, 0.006047090981155634, 0.006016592960804701, 0.02682332880795002, 0.14134566485881805, -0.043912943452596664, 0.06355556845664978, -0.0047...
some\tbioavailability\t(see\t\nAppendix\t39\n).\nRecommended\tintakes\nIn\tadults,\trecommended\tintakes\tof\tCa\n++\n\trange\tfrom\t1000\tto\t1300\n\tmg/day,\tdepending\ton\tage\tand\ngender.\tAn\tupper\tlimit\tfor\tCa\n++\n\tintake\thas\tbeen\testimated\tto\tbe\tapproximately\t2500\tto\t3000\tmg/day\n(see\tinside\tco...
[ -0.05754052475094795, -0.019689999520778656, 0.02925199642777443, -0.01244882307946682, -0.10181092470884323, -0.06841246038675308, 0.08885352313518524, 0.04018810763955116, -0.02737518958747387, 0.0233510360121727, 0.07565508782863617, -0.04819650202989578, 0.05489072948694229, 0.03315336...
(see\tinside\tcover).\tExcessive\tintake\tof\tCa\n++\n\tmay\tlead\tto\tkidney\tstones\tand\tgastrointestinal\tside\neffects\tlike\tconstipation.\nSodium\nSodium\t(Na\n+\n)\tis\tthe\tmajor\tcation\tof\tECF\twith\ta\tnormal\trange\tof\t135\tto\t145\tmEq/L\t(refer\tto\tthe\nreference\tranges\tfor\teach\treporting\tlaborat...
[ -0.012907704338431358, -0.0681128278374672, 0.051880333572626114, -0.00818831566721201, -0.07580670714378357, -0.016399377956986427, 0.11410310864448547, -0.009925104677677155, 0.004755462519824505, 0.036268774420022964, 0.09345157444477081, -0.030461885035037994, 0.05806973576545715, 0.04...
Secretions\tsuch\tas\tbile\tand\tpancreatic\tjuice\tcontain\nsubstantial\tamounts\tof\tNa\n+\n.\tGastric\tsecretions\tand\tdiarrhea\talso\tcontain\tNa\n+\n,\tbut\tcontrary\tto\ncommon\tbelief,\tsweat\tis\thypotonic\tand\tcontains\ta\trelatively\tsmall\tamount\tof\tNa\n+\n.\tApproximately\n35%\tto\t40%\tof\tthe\ttotal\t...
[ -0.004765362478792667, -0.05216163396835327, 0.028155125677585602, -0.019627217203378677, -0.07160817086696625, 0.004392796196043491, 0.11914770305156708, 0.025884127244353294, -0.011336280964314938, 0.09131892770528793, 0.09665513038635254, -0.06839308142662048, 0.011880106292665005, 0.05...
+\n\tis\tin\tthe\tskeleton\tand\tthe\tremainder\tis\tin\tbody\tfluids.\nFunctions\nAs\tthe\tpredominant\tion\tof\tthe\tECF,\tNa\n+\n\tthus\tregulates\n\textracellular\tand\tplasma\tvolume.\tNa\n+\n\tis\talso\nimportant\tin\tneuromuscular\tfunction\tand\tmaintenance\tof\tacid–base\tbalance.\tMaintenance\tof\tserum\nNa\n...
[ 0.008589996956288815, -0.057170577347278595, 0.023528805002570152, -0.04293934255838394, -0.08955702930688858, 0.007183422334492207, 0.08975014090538025, 0.06158498674631119, -0.018391845747828484, 0.08966758847236633, 0.09817847609519958, -0.04263196885585785, 0.008047719486057758, 0.0586...
Na\n+\n\tlevels\tis\tvital,\tbecause\tsevere\t\nhyponatremia\n\tcan\tlead\tto\tseizures,\tcoma,\tand\tdeath.\nExtracellular\tNa\n+\n\tconcentrations\tare\tmuch\thigher\tthan\tintracellular\tlevels\t(normal\tserum\tNa\n+\n\tis\naround\t135\tmEq/L,\twhereas\tintracellular\tlevels\tare\taround\t10\tmEq/L).\tThe\n\tsodium-...
[ -0.035407278686761856, -0.07209660857915878, 0.06300007551908493, -0.019582532346248627, -0.048880286514759064, -0.0005169973592273891, 0.0769898071885109, 0.056007031351327896, -0.04527246206998825, 0.044202420860528946, 0.060467302799224854, -0.08284006267786026, 0.04546982795000076, 0.0...
pump\tis\tan\tactive\ttransport\tsystem\tthat\tworks\tto\tkeep\tNa\n+\n\toutside\tthe\tcell\tthrough\texchange\twith\npotassium.\tThe\tNa/K-ATPase\tpump\trequires\tcarriers\tfor\tNa\n+\n\tand\tpotassium\talong\twith\tenergy\tfor\nproper\tfunction.\tExportation\tof\tNa\n+\n\tfrom\tthe\tcell\tis\tthe\tdriving\tforce\tfor...
[ -0.01797350123524666, -0.0613417886197567, 0.0745777040719986, -0.08634809404611588, -0.06366883218288422, 0.029468711465597153, 0.13636356592178345, -0.014755511656403542, -0.028681110590696335, 0.028051448985934258, 0.06542355567216873, -0.03205256909132004, 0.022743770852684975, 0.08296...
+\n\tfrom\tthe\tcell\tis\tthe\tdriving\tforce\tfor\tfacilitated\ttransporters,\nwhich\timport\tglucose,\tamino\tacids,\tand\tother\tnutrients\tinto\tthe\tcells.\nHyponatremia.\nAssessing\thyponatremia\tor\thypernatremia\ttakes\tinto\tconsideration\tthe\trole\tof\tNa\n+\n\tin\tregulating\tfluid\nbalance\tand\trequires\t...
[ 0.010412376374006271, -0.04236278682947159, 0.03680361807346344, -0.0321391299366951, -0.08028582483530045, 0.03832771256566048, 0.09550470113754272, -0.006215971428900957, 0.007057512179017067, 0.07443632930517197, 0.11623752862215042, -0.04479474201798439, 0.05148255452513695, 0.01329270...
common\telectrolyte\tdisorders\tamong\thospitalized\tpatients\tand\toccurs\tin\t25%\tof\tinpatients.\tWhen\nhyponatremia\tis\tbelow\t125\tmEq/L,\tsymptoms\tgenerally\tbecome\tapparent.\tPatients\tmay\tdisplay\tsigns\nof\theadache,\n\tlethargy,\trestlessness,\tdecreased\treflexes,\tseizures,\tor\tcoma\tin\textreme\tcase...
[ 0.02488674409687519, -0.04355417191982269, 0.02588420733809471, -0.04719782620668411, -0.11077125370502472, -0.017597036436200142, 0.07905878871679306, 0.060732875019311905, 0.003289044601842761, 0.010039820335805416, 0.11909656226634979, -0.011467396281659603, 0.029734348878264427, 0.0230...
are\tthree\tbasic\tcauses\tfor\thyponatremia.\tHypertonic\thyponatremia\tis\tdue\tto\texcess\tdelivery\tof\nmannitol\tor\thyperglycemia,\twhich\tcauses\tserum\tNa\n+\n\tto\tincrease\tby\t1.6\tmEq\tfor\tevery\t100\tmg/dL\nrise\tin\tserum\tglucose.\tMannitol\tis\tsometimes\tused\tfor\tthe\ttreatment\tof\tcerebral\tedema\...
[ -0.0057029519230127335, -0.05471217632293701, 0.05469764396548271, -0.0324828065931797, -0.07357287406921387, 0.035021740943193436, 0.0816793218255043, -0.00267637986689806, 0.008289250545203686, 0.06949355453252792, 0.0880182757973671, -0.04648762196302414, 0.05179130658507347, 0.02048071...
failure.\tIt\tincreases\tserum\n\tosmolality,\twhich\tleads\tto\tdilutional\thyponatremia\tfrom\twater\tmovement\nout\tof\tthe\tcells.\tIsotonic\thyponatremia\toccurs\tin\tthe\tpresence\tof\thyperlipidemia\tor\nhyperproteinemia,\tbecause\tthe\taqueous\tcomponent\tthat\tNa\n+\n\tis\tdissolved\tand\tresults\tin\ta\tfalse...
[ 0.0009902419988065958, -0.03155379742383957, 0.054987259209156036, 0.0025618693325668573, -0.035677991807460785, 0.04735295847058296, 0.07041367143392563, 0.01952468603849411, 0.0010680998675525188, 0.056238021701574326, 0.06977829337120056, -0.02967005968093872, 0.07692315429449081, 0.016...
+\n\tis\tdissolved\tand\tresults\tin\ta\tfalsely\tlow\nvalue\t(this\tis\tmainly\ta\tlaboratory\tartifact\tand\tis\tnot\toften\tseen\tin\tclinical\tpractice).\tThe\tfinal\ttype\tis\nhypotonic\thyponatremia.\tEvaluation\n\tdepends\ton\tfluid\tstatus\tto\tevaluate\tthe\tthree\tsubtypes.\nIsovolemic\thyponatremia\tcan\tbe\...
[ 0.020879758521914482, -0.039881087839603424, 0.06542271375656128, -0.00807303749024868, -0.08634532243013382, 0.017768310382962227, 0.06394972652196884, 0.01820417493581772, -0.0010930999414995313, 0.045923758298158646, 0.08964674174785614, -0.0363335981965065, 0.013734587468206882, 0.0094...
inappropriate\tantidiuretic\thormone\tsecretion\t(SIADH).\tSIADH\t(see\t\nChapter\t30\n)\tcan\tresult\tfrom\ncentral\tnervous\tsystem\tdisorders,\tpulmonary\tdisorders,\ttumors,\tand\tcertain\tmedications.\tThe\ntreatment\tis\tusually\twater\trestriction.\tHypervolemic\thypotonic\n\thyponatremia\tis\tcharacterized\tby\...
[ -0.00815259013324976, 0.029510200023651123, 0.09099604934453964, -0.007498504593968391, -0.031157203018665314, -0.0004244060255587101, 0.05162762850522995, 0.017847664654254913, -0.016756996512413025, 0.025887344032526016, 0.06783779710531235, -0.031609661877155304, 0.024442465975880623, 0...
excess\tTBW\tand\tNa\n+\n\t(overall\thigher\texcess\twater\tthan\tNa\n+\n)\tbecause\tof\treduced\texcretion\tof\twater\nor\texcess\tfree\twater\tadministration.\tCardiac,\trenal,\tor\thepatic\tfailure\tare\tthe\tmost\tcommon\tcauses,\nand\tpatients\thave\tedema\tor\tascites\ton\tphysical\texamination.\tThe\ttreatment\t...
[ -0.026797648519277573, -0.04084966331720352, 0.06429916620254517, -0.017829742282629013, -0.05466246232390404, -0.04039899632334709, 0.03877099230885506, 0.062860868871212, -0.006003297865390778, 0.012780028395354748, 0.02645612694323063, -0.043983474373817444, 0.05032511055469513, 0.04823...
diuretics\tto\taid\tin\tdecreasing\tTBW,\tand\toral\tNa\n+\n\trestriction\talso\tmay\n\tbe\tbeneficial.\tThe\tfinal\ttype\tis\nhypovolemic\thypotonic\thyponatremia,\tcharacterized\tby\ta\tdeficit\tin\tTBW\tand\tNa\n+\n\tthat\trequires\ntreatment\twith\tfluid\treplacement.\tOften\tfluid\tlosses\tleading\tto\thypovolemia...
[ -0.024745583534240723, -0.029731623828411102, 0.07060842216014862, -0.02175581268966198, -0.03813639655709267, 0.004349173977971077, 0.07786112278699875, 0.043292805552482605, -0.02239898219704628, 0.04692334681749344, 0.09869006276130676, -0.01797449216246605, 0.020338375121355057, 0.0299...
excessive\tvomiting,\texcessive\tsweating\t(marathon\tathletes),\tdiarrhea,\twound\tdrainage/burns,\thigh-\nvolume\tgastrointestinal\tsecretions,\tor\texcessive\tdiuretic\tuse.\tEquations\tto\tcalculate\n\tfluid\tdeficits\tcan\nbe\tused\tto\treplace\thalf\tof\tthe\tfluid\tdeficit\tin\tthe\tfirst\t24\thours.\tCorrecting...
[ 0.0023380920756608248, -0.07574398815631866, 0.07458126544952393, 0.010503041557967663, -0.08502563834190369, -0.04755163565278053, 0.07231534272432327, 0.042848844081163406, -0.04005301371216774, 0.0028090798296034336, -0.014363988302648067, -0.009755700826644897, 0.01312627550214529, 0.0...
+\n\tlevels\tmust\tbe\tdone\nslowly\t(max\tof\t8\tto\t12\tmEq\tin\t24\thours)\tto\tprevent\tosmotic\tdemyelinating\tsyndrome\tthat\tis\tseen\twith\nrapid\tcorrection\t(\nRhoda\tet\tal,\t2011\n).\nHypernatremia.\nA\tserum\tNa\n+\n\tlevel\tgreater\tthan\t145\tmEq/L\tis\tclassified\tas\thypernatremia,\tand\tthere\tare\tva...
[ -0.0069588483311235905, -0.036916304379701614, 0.03419170901179314, -0.051228053867816925, -0.06931916624307632, 0.04011259973049164, 0.052046291530132294, 0.028783511370420456, -0.025523101910948753, 0.05583735182881355, 0.09521281719207764, -0.023534612730145454, 0.07107935100793839, 0.0...
types.\tHypovolemic\thypernatremia\n\tis\tcaused\tby\ta\tloss\tof\tNa\n+\n\tand\tTBW\twhen\twater\tlosses\texceed\nNa\n+\n\tlosses.\tIt\tis\timportant\tto\tidentify\tthe\tcause\tof\tthe\tfluid\tlosses\tso\tthat\tthey\tcan\tbe\tcorrected\tand\nprevented\tin\tthe\tfuture.\tThe\ttreatment\tis\tto\tslowly\treplace\tfluid\t...
[ 0.0027957104612141848, -0.016781451180577278, 0.05786323547363281, -0.026179643347859383, -0.09133248776197433, 0.022985560819506645, 0.07975415885448456, 0.0062532080337405205, -0.003727678209543228, 0.0524621456861496, 0.056511472910642624, -0.034531936049461365, 0.03017779439687729, 0.0...
solution.\tHypervolemic\thypernatremia\tis\tcaused\tby\texcessive\tintake\tof\tNa\n+\n\tresulting\tin\thigher\tNa\n+\ngain\tthan\twater\tgains.\tThe\ttreatment\tis\n\tto\trestrict\tNa\n+\n\t(especially\tin\tintravenous\tfluids)\tand\tpossibly\nthe\tuse\tof\tdiuretics.\tIsovolemic\thypernatremia\tis\tseen\twith\tdisease...
[ -0.008760511875152588, -0.0207255519926548, 0.09011442214250565, -0.05245416983962059, -0.10585565865039825, -0.007383519783616066, 0.10805417597293854, 0.034635089337825775, -0.04664761200547218, 0.056596092879772186, 0.06614845991134644, -0.06933508068323135, 0.022252630442380905, 0.0713...
Signs\tof\thypernatremia\tinclude\tlethargy,\tthirst,\thyperreflexia,\tseizures,\tcoma,\tor\tdeath.\tFormulas\tfor\ncalculating\ta\twater\tdeficit\tare\thelpful\tto\tguide\tfluid\treplacement.\tFree\twater\tdeficit\tis\tcalculated\tas\nfollows\t(\nKingley,\t2005\n):
[ 0.004973954055458307, -0.03338581696152687, 0.052289288491010666, -0.017095446586608887, -0.0324341244995594, 0.023483114317059517, 0.02225009724497795, 0.003750792471691966, 0.005508992355316877, 0.02375619485974312, 0.07684878259897232, -0.06750776618719101, 0.02915685623884201, 0.014826...
Absorption\tand\texcretion\nNa\n+\n\tis\tabsorbed\treadily\tfrom\tthe\tintestine\tand\tcarried\tto\tthe\tkidneys,\twhere\tit\tis\tfiltered\tand\nreturned\tto\tthe\tblood\tto\tmaintain\tappropriate\tlevels.\tThe\tamount\tabsorbed\tis\tproportional\tto\tthe\nintake\tin\thealthy\tadults.\nAbout\t90%\tto\t95%\tof\tnormal\t...
[ 0.0426957830786705, -0.0447741262614727, 0.08188055455684662, -0.003852296620607376, -0.0860157385468483, -0.014767316170036793, 0.15229356288909912, 0.0014802971854805946, -0.01956401765346527, 0.05848969146609306, 0.07897602766752243, -0.047398123890161514, 0.03719460219144821, 0.0332209...