OTAR3088/BioData-CellLine_annotated · Datasets at Hugging Face

PMCID string	Sentences string	ner list
PMC11726183	1-Benzylindoline-2,3-dione (3) was synthesized from commercially available indoline-2,3-dione (1) in the first step.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "1-Benzylindoline-2,3-dione", "(", "3", ")", "was"...
PMC8357004	Recently, it has become clear that the silencing of cancer-related TSGs INK4 is not exclusively a result of mutations or deletions, but it can also be because of histone deacetylation and DNA hypermethylation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Results: During the induction phase, 19 out of 178 (10.6%) patients who received L-ASNase during induction developed VTE, whereas 21 out of 71 (29.6%) patients with PEG-ASNase developed VTE (p-value = 0.0002, OR = 3.079, 95 CI 1.43-6.64), with multivariable analysis after adjusting for age, sex, weight, and central line types.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9000591	Moreover, plant resources are extremely abundant and well-distributed all over the world .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "plant", "resources", "are", "extremely", "abundant", "and"...
PMC11599565	Panel A: combination treatment of cisplatin and GSIs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Panel", "A", ":", "combination", "treatment", "of", "cisplatin", "and", "GSIs", "." ] } ]
PMC8336407	A similar trend was shown when cells treated with 2.5 mg/mL concentration of the extract were exposed to 100 µM, 150 µM, and 200 µM concentrations of t-BHP in which the parameter dropped to 3832 ± 34.49, 3508 ± 23.93, and 3075 ± 97.91 µM respectively (p < 0.001). (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11248911	Calcd.	[ { "tags": [ "O", "O" ], "tokens": [ "Calcd", "." ] } ]
PMC11345828	The title compound (34 mg, 45% yield) was prepared following General Procedure F using compound 48 (70 mg, 0.089 mmol, 1.0 equiv) and (S)-(tetrahydrofuran-2-yl)methyl 4-methylbenzenesulfonate (75 mg, 0.29 mmol, 3.2 equiv) followed by saponification using General Procedure G. LCMS Method 2: RT = 1.353 min, MS (ESI): mass calcd for C45H47Cl2N5O7, 839.3, m/z found 839.8 (M + H).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4395774	Cr release cytotoxicity assay and IFN-γ assay.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cr", "release", "cytotoxicity", "assay", "and", "IFN-γ", "assay", "." ] } ]
PMC9429973	Summary/Conclusion: Several of the enzymes regulating these RNA modifications are essential for myeloma cell lines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Summary/Conclusion", ":", "Several", "of", "the", "enz...
PMC8864075	reTFAE inhibited the EMT process of A549 cells via inhibiting TWIST1. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O" ], "tokens": [ "reTFAE", "inhibited", "the", "EMT", "process", "of", "A549", "cells", "...
PMC11794847	The results of blood showed that the proportional of CD3, CD4, CD8, NK, and DC cells in the HVEM KO group was lower than wild type, and the proportional of Treg cells was higher than wild type group (Figure S9A–B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11693599	In addition, high CD109 expression levels in tumors are associated with a poor prognosis (12, 14).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "addition", ",", ...
PMC11055323	Outside and inside groups indicate the distribution of random pixels’ fluorescence intensity normalized by Z score from outside and inside of SS18-SSX, N12 fused SS18-SSX and N12 with R3A or K5A mutation fused SS18-SSX condensates, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11711871	Significant difference between the two genotypes under the same diet (NSD or HSD); † and # indicate significant differences between the HSD and NSD groups within the (†) GR or (#) wild-type rats.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	With modern day treatments, long remissions are often achieved both in front-line and relapsed setting.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "With", "modern", "day", "treatments", ",", "long", ...
PMC11587541	Firstly, the small sample size could compromise the generalizability of the findings due to limited representation of the diverse population.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Firstly", ",", "t...
PMC11185260	Furthermore, Western blot analysis of BT-12 cells treated with scL-SMARCB1 showed distinct bands of the exogenous SMARCB1 protein at 44kDa at all time points (Figure 2C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11627133	N=50 cells) of HEK293T cells expressing H2B‐GFP from confocal images as shown in D).	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "N=50", "cells", ")", "of", "HEK...
PMC11228511	Western blot comparing the expression of lamin A and progerin in the mouse aorta and in cultured SMCs expressing Dox-inducible constructs for human (hu)-prelamin A and hu-progerin.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	TRAEs of any grade occurred ≥20% of patients were neutropenia (36.8%), leukopenia (31.5%), ALT elevation (31.5%), AST elevation (26.3%), hyperphosphatemia (21%), hyperuricemia (21%), and diarrhea (21%).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3813807	These data indicate that miRNAs are involved in gastric carcinogenesis via a variety of patterns and pathways and that it may be possible to manipulate miRNA to achieve therapeutic effects.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11599565	For instance, MDA-MB-231 PGCCs activate programs resembling osteogenesis, chondrogenesis and adipose differentiation after culturing in differentiation media.	[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "instance", ",", "...
PMC9351137	A Total CRS amount assessed by Western blotting in RNAi-treated and mock-treated cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "Total", "CRS", "amount", "assessed", "by", "Western", "blotting", ...
PMC9985266	Aberrant IL-27 expression was observed in BLM-induced mouse lung tissues, and the use of IL-27 attenuated mouse lung tissue fibrosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aberrant", "IL-27", ...
PMC11536589	The expression levels of MGST1 in parental PDAC cells and MRTX1133-resistant PDAC cells. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "expression", "levels", "of", "MGST1", "in", "parental", "...
PMC9581083	Clinical evidence continues to grow in support of JSHD as an adjuvant treatment in COVID-19 infection (Shibu et al., 2022).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Clinica...
PMC11763111	Most studies assessing the efficacy of CAR-T cell therapy have employed NSG mice to establish cell line-derived xenograft (CDXs) models .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Most", "stud...
PMC9927933	Interestingly, the levels of DEPTOR, like all other proteins tested and known to fluctuate with the cell cycle, indeed fluctuated during cell cycle progression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The mortality in the ICU was 88% (22 pts).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "mortality", "in", "the", "ICU", "was", "88", "%", "(", "22", ...
PMC11682224	M2-type macrophages normally have anti-inflammatory and tissue-repair-promoting functions, but in the tumour environment they mainly promote tumour growth, angiogenesis, stromal remodelling, and immune escape.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	In patients, clonal T cell expansion and activation, IFN-g and TNF-α upregulation, and Fas mediated cell death, lead to severe BM destruction and the development of AA.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10522430	In 6-well plates, a total of 1 × 10 HeLa cells were subjected to incubation with G. applanatum extract and medium under 5% CO2 at 37°C overnight.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4839679	n = 3 independent biological replicate experiments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "n", "=", "3", "independent", "biological", "replicate", "experiments", "." ] } ]
PMC11013014	172 °C (degradation).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "172", "°", "C", "(", "degradation", ")", "." ] } ]
PMC8097906	Statistically significant differences were compared using the unpaired Student’s t-test.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Statistically", "significant", "differences", "were", "compared", "using", "the", "unpaired", ...
PMC11549062	Carotid VSMCs were plated in a six‐well plate and subjected to transfection and treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Carotid", "VSMCs", "were", "plated", "in", "a", "six‐well", "pla...
PMC9429973	Accelerated CLL/SLL (aCLL/SLL) is pathologically defined as a highly proliferative form of CLL/SLL (either expanded proliferation center or Ki-67>40%).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC6617630	Based on the MYC, BCL2, and BCL6 rearrangements, DLBCL cell lines were determined to fall into either wild-type MYC (WT-MYC) seen in HBL-1 and U2932 cell lines; single MYC rearrangement with immunoglobulin commonly referred to as single hit (MYC/IG; SH) seen in Raji and Ramos Burkitt lymphoma cell lines; MYC rearrangement with BCL2 gene (MYC/BCL2; DHL) seen in OCILY1, OCILY10, SUDHL2, and DOHH2 cell lines; or MYC rearrangements with both BCL2 and BCL6 genes (MYC/BCL2/BCL6; THL) seen in only VAL cell line (Table 1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7685376	Relative expression levels of MCM2, MCM3, and MCM4 in 369 HCC tissues and 160 normal tissues got form GEPIA database. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Relativ...
PMC11351758	Then, the slides were stained for 30 min.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Then", ",", "the", "slides", "were", "stained", "for", "30", "min", "." ] } ]
PMC11696576	All box and whisker plots show the mean (center line), stdev (box), and min and max values (whiskers) from 4 biological replicates.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9024365	Next, we looked at changes in the mean area of GluA1 clusters as a result of chemical-LTP.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Next", ",", "we", "looked", "at", ...
PMC11594074	After incubation for 72 h, 20 µL of 0.01% resazurin solution was added to each well and again incubated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "incubation", ...
PMC10197932	CD69 also interacts with LAT-1 (amino acid transporter, tryptophan transporter) 22 suggesting its functional role in switching metabolism during activation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CD69", ...
PMC3019555	HIF-1α, the oxygen-regulated subunit of HIF-1, is found overexpressed in >70% of all human tumors, and its expression is correlated with poor prognosis and resistance to therapy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10380508	MTT assays were carried out using the Cell Proliferation Kit (Roche Applied Science, Penzberg, Bavaria, Germany) at selected time-points, following the manufacturer’s instructions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Eight comprehensive geriatric assessment (CGA) domains were analyzed in 135 of these patients to screen items most closely associated with the outcomes, including grade ≥ 3 adverse events (AEs), treatment discontinuation, TTP, and OS.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11711871	All animals were housed in a humidity- (< 40%) and temperature-controlled room (23 ± 1 °C) with an automatic 12-h light/dark cycle (light: 7 am to 7 pm) in ventilated cages with free access to food (normal salt diet, NSD; 0.25% Na and 0.70% K diet; Provimi Kliba AG; number 3242-XP18, Switzerland, hereinafter referred to as the standard diet) and tap water in an approved animal care facility of the University of Lausanne.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11643491	The ability to selectively target specific cell types by exploiting their unique mechanical properties can also be valuable for the development of more precise immunotherapies, where particle shape may influence the interaction between immune cells and nanoparticles designed for vaccination or cancer immunotherapy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11487720	A COS7 cells were UV irradiated (480 mJ/cm) and cold shocked for indicated times, which led to rapid downregulation of cortactin and α-tubulin.	[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10996034	At the same time, in order to investigate the association of Taxol resistance of EOC with disease stage, the associations between MMP1, ZYX and UNC5C, and the disease stage of EOC (stage II, III and IV) were examined.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Differences were considered statistically significant at p<0.05.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Differences", "were", "considered", "statistically", "significant", "at", "p<0.05", "." ] } ]
PMC8978939	The crystal structure of a human VBC: HIF-1α complex PDB 4AJY (X-Ray diffraction, 1.73 Å resolution) was used as starting structure (41).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6650823	Thi et al. tried to discover novel multi-target agents with better anti-tumor activities than celecoxib.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thi", "et", "al.", "tried", "to", "discover", "novel", ...
PMC11462673	Additionally, visualization of liver and spleen samples of mice using fluorescence imaging indicated a substantial reduction in tumor burden within the LDB1 knockdown group when compared to the control group (Fig. 3C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	No serious adverse event (SAE) occurred.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "No", "serious", "adverse", "event", "(", "SAE", ")", "occurred", "." ] } ]
PMC11679033	Combined exposure to both compounds resulted in a lowering of primary and cytogenetic DNA damage caused by CIT.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Combined", "exposure", "to", "both", "...
PMC11697065	Unconventional biological drugs with complex structures and processing requirements are particularly problematic.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Unconventional", "biological", "drugs", "with", "complex", "structures", "and", "proce...
PMC4270159	Meta-analysis of original and replication attempt effect sizes:We will plot the replication data (mean and 95% confidence interval) and will include the original data point, calculated directly from the representative image in Figure 2C, as a single point on the same plot for comparison.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9516401	Phenolic content of in P. vulgaris, C. colocynthis, P. oleracea, A. cepa, and C. verum extract The content of total phenols in the extract of A. cepa, C. colocynthis, P. vulgaris, P. oleracea and C. verum was 28, 40, 22, 57, and 372 mg gallic acid equivalent per gram of the crude extract, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11534035	Strong evidence of this function has been discovered in the realm of gynecological oncology, specifically in breast, ovarian, and most recently also in VCs (10,14,19-22).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11026382	These discrepancies between true and effective kcat could be addressed in future work by including additional high-throughput assay data on stability or abundance to tease apart mutational effects on catalysis from stability and abundance.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11024707	ASD is a phenotypically heterogeneous clinical spectrum, and affected individuals are influenced at different levels.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ASD", "is", "a", "phenotypically", "heterogeneous", "c...
PMC11742290	Their research showed that LGR5 + cells contributed to the maintenance and regeneration of the epithelial lining in both the ovary and the fallopian tube .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11752740	Additionally, a notable decrease was found between the combined treatment at 48 h and that at 24 h (denoted with †), indicating that the drug-extract combination’s efficacy improves over time.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11627133	In these experiments, we utilized the single‐stranded DNA aptamer AS1411, which targets nucleolin, a highly abundant protein found in the nucleolus.[ , ]	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10890307	Calu-1 had the highest qP Lactate when it was grown using glucose at a pH of 7.2 under normoxia (Glc/pH7.2/N); MRC-5 had the highest qP Lactate in comparison with the other tumor cell lines when it was grown in Glc/pH7.2/H, glucose-containing media at a pH of 6.2 and under normoxia (Glc/pH6.2/N), and glucose-containing media at a pH of 6.2 and under hypoxia (Glc/pH6.2/H) (Table 3 and Table 4).	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "...
PMC9622879	By using the variable s(t), our optimization problem can be transformed into28[12pt] $$ min _^ C_(t), $$∑t=1TCCom(t),subject to:29[12pt] $$&C_(t) ( _^E_^(t) - _^E_^(t)) P_(t) - M (1-s(t)) $$(t)≥∑i=1NEi,Combuy(t)-∑i=1NEi,Comsell(t)·PMG(t)-M·(1-s(t))30[12pt] $$&C_(t) ( _^E_^(t) - _^E_^(t)) P_(t) + M (1-s(t)) $$(t)≤∑i=1NEi,Combuy(t)-∑i=1NEi,Comsell(t)·PMG(t)+M·(1-s(t))31[12pt] $$&C_(t) ( _^E_^(t) - _^E_^(t)) P_(t) - M s(t) $$(t)≥∑i=1NEi,Combuy(t)-∑i=1NEi,Comsell(t)·α·PMG(t)-M·s(t)32[12pt] $$&C_(t) ( _^E_^(t) - _^E_^(t)) P_(t) + M s(t) $$(t)≤∑i=1NEi,Combuy(t)-∑i=1NEi,Comsell(t)·α·PMG(t)+M·s(t)and33[12pt] $$ (1)(18), (24), (26), (27), (29)(32).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11216402	Three hundred fifty-six tumor (TCGA-STAD) and 32 normal stomach (TCGA-Normal) samples were initially obtained.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Three", "hundred", "fifty-six", "tumor", ...
PMC11040965	However, the molecular events that link CD28 activation to proteasome subunit downregulation have not been determined.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "the", "molecular", "events", ...
PMC9429973	No discontinuations due to RG6234-related AEs occurred.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "No", "discontinuations", "due", "to", "RG6234-related", "AEs", "occurred", "." ] } ]
PMC11349530	According to the studies that evaluated the ability of tumor cells to produce various cytokines, VEGF is one of the most intensively produced cytokines by various tumor cells (76–78).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11423992	A11138-03, Gibco).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A11138", "-", "03", ",", "Gibco", ")", "." ] } ]
PMC11599565	Panel A: expression of cardinal transcription factors defining a neuronal phenotype and structural proteins.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Panel", "A", ":", "expression", "of", "cardinal", "transcri...
PMC9817179	D–F) Quantification of puncta parameters after fixation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "D", "–", "F", ")", "Quantification", "of", "puncta", "parameters", "after", "fixation", "....
PMC11139449	FlowJo (version 7.6) software was used to examine the data.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "FlowJo", "(", "version", "7.6", ")", "software", "was", "used", "to", "exa...
PMC11545737	YopE and YopT are Rho-modifying enzymes, YopE is a GTPase-activating protein while YopT is a protease.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "YopE", "and", "YopT", "are", "Rho-modifying", ...
PMC9592219	In this study, we aimed to explore the TOP2A tumor-promoting effects and elucidate whether TOP2A regulates the activity of YAP1 in the Hippo signaling pathway by binding to β-catenin to exert biological effects.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5535901	Our data show novel insights into the mechanisms underlying induction of pro-inflammatory cytokine release by pharmacological concentrations of I3C and DIM, an effect negligible under physiological conditions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11317131	PE uses a fusion protein consisting of a Cas9 nickase and reverse transcriptase called PE5, as well as a prime editing guide RNA (pegRNA) (31).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11307990	Taken together, this study provides a promising candidate platform for the delivery of cell membrane receptor inhibitors in anticancer therapy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Taken", "together", ...
PMC10877303	Molecular docking analysis facilitated the selection of the three best compounds based on their binding energy, namely Kihadanin B, Robustaflavone, and 3-beta-O-(trans-p-Coumaroyl)maslinic acid.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11770130	To investigate whether the changes in lipolysis were due to the cell-autonomous effects of the NTS-NTSR2 signaling, we treated the primary adipocytes derived from SVF with recombinant NTS peptides.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3813807	These observations indicate that TNFAIP1 is negatively regulated by miR-373.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "observations", "indicate", "that", "TNFAIP1", "is", "negatively", "regulated", "by", "m...
PMC10810426	These findings suggest that simple retroviruses, like the complex retrovirus HIV, gain nuclear entry by traversing the nuclear pore complex in non-mitotic cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973	Overall, the median NAB was 2 with no significant difference between the two COO subgroups (Kruskal wallis chi-squared 0.63, p= 0.42).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC4485786	Nuclei were stained with Yopro (1:2000; Invitrogen, Germany) for 5 min before mounting the slides with Mowiol (Hoechst, Germany).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC8382973	The pH 4.4 or pH 7.4 of both gels was similar to that of the vaginal and rectal environment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "pH", "4.4", "or", "p...
PMC8143558	For plants such as legumes, biotic factors such as the presence of symbiotic mycorrhizal fungi enhance production of higher quantities of better-quality phytochemicals .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9031474	Proper target identification will lay a solid basis for future lead compound discovery and candidate selection for preclinical and clinical development.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Proper", "target", ...
PMC11679326	Another representative C1qDC protein in marine invertebrates OXYL from marine star Anneissia japonica can bind to N-acetyllactosamine (LacNAc) type 2 (Galβ1,4GlcNAc) but does not recognize LacNAc type 1 (Galβ1,3GlcNAc), and it could recognize breast cancer BT-474, MCF-7, and T47D cells without exhibiting cytotoxicity .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11680578	β-actin and PPAR-α were used as housekeeping genes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "β-actin", "and", "PPAR-α", "were", "used", "as", "housekeeping", "genes", "." ] } ]
PMC9436459	There are only four compounds in type E-II MDAAs, two (124 and 125) of which feature the C-6 dehydroprenyl and two (126 and 127) feature the C-8 dehydroprenyl.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11144200	B The CD8 T cells above were stained with CFSE-conjugated anti-CD25 or anti-CD69 or CD62L mAb and analyzed by flow cytometry for activation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "B", ...
PMC10956161	The correlation between the PRDX6 gene and these 20 genes was analysed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "correlation", "between", "the", "PRDX6", "gene", "and", "these", "20", ...
PMC11666785	Multiphoton variant of super-resolution microscopy has enabled better penetration depths suitable for scattering medium such as tissue.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Multiphoton", "variant", "of", "super-resolution", ...
PMC10587429	Paraformaldehyde (PFA, 158127, Millipore Sigma, Burlington, MA). -	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Paraformaldehyde", "(", "PFA", ",", "158127", ",", "Millipore", ...
PMC9429973	Targeted sequencing was performed on DNA samples using the TruSight Myeloid Sequencing Panel.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Targeted", "sequencing", "was", "performed", "on", "DNA", "samples", "using...
PMC11622247	In spite of challenges with the amount of probes delivered into T cells, the evidence suggests that the probes engage with their target.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC11726183

1-Benzylindoline-2,3-dione (3) was synthesized from commercially available indoline-2,3-dione (1) in the first step.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "1-Benzylindoline-2,3-dione", "(", "3", ")", "was"...

PMC8357004

Recently, it has become clear that the silencing of cancer-related TSGs INK4 is not exclusively a result of mutations or deletions, but it can also be because of histone deacetylation and DNA hypermethylation.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Results: During the induction phase, 19 out of 178 (10.6%) patients who received L-ASNase during induction developed VTE, whereas 21 out of 71 (29.6%) patients with PEG-ASNase developed VTE (p-value = 0.0002, OR = 3.079, 95 CI 1.43-6.64), with multivariable analysis after adjusting for age, sex, weight, and central line types.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9000591

Moreover, plant resources are extremely abundant and well-distributed all over the world .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "plant", "resources", "are", "extremely", "abundant", "and"...

PMC11599565

Panel A: combination treatment of cisplatin and GSIs.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Panel", "A", ":", "combination", "treatment", "of", "cisplatin", "and", "GSIs", "." ] } ]

PMC8336407

A similar trend was shown when cells treated with 2.5 mg/mL concentration of the extract were exposed to 100 µM, 150 µM, and 200 µM concentrations of t-BHP in which the parameter dropped to 3832 ± 34.49, 3508 ± 23.93, and 3075 ± 97.91 µM respectively (p < 0.001). (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11248911

Calcd.

[ { "tags": [ "O", "O" ], "tokens": [ "Calcd", "." ] } ]

PMC11345828

The title compound (34 mg, 45% yield) was prepared following General Procedure F using compound 48 (70 mg, 0.089 mmol, 1.0 equiv) and (S)-(tetrahydrofuran-2-yl)methyl 4-methylbenzenesulfonate (75 mg, 0.29 mmol, 3.2 equiv) followed by saponification using General Procedure G. LCMS Method 2: RT = 1.353 min, MS (ESI): mass calcd for C45H47Cl2N5O7, 839.3, m/z found 839.8 (M + H).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC4395774

Cr release cytotoxicity assay and IFN-γ assay.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cr", "release", "cytotoxicity", "assay", "and", "IFN-γ", "assay", "." ] } ]

PMC9429973

Summary/Conclusion: Several of the enzymes regulating these RNA modifications are essential for myeloma cell lines.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Summary/Conclusion", ":", "Several", "of", "the", "enz...

PMC8864075

reTFAE inhibited the EMT process of A549 cells via inhibiting TWIST1. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O" ], "tokens": [ "reTFAE", "inhibited", "the", "EMT", "process", "of", "A549", "cells", "...

PMC11794847

The results of blood showed that the proportional of CD3, CD4, CD8, NK, and DC cells in the HVEM KO group was lower than wild type, and the proportional of Treg cells was higher than wild type group (Figure S9A–B).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11693599

In addition, high CD109 expression levels in tumors are associated with a poor prognosis (12, 14).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "addition", ",", ...

PMC11055323

Outside and inside groups indicate the distribution of random pixels’ fluorescence intensity normalized by Z score from outside and inside of SS18-SSX, N12 fused SS18-SSX and N12 with R3A or K5A mutation fused SS18-SSX condensates, respectively.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11711871

Significant difference between the two genotypes under the same diet (NSD or HSD); † and # indicate significant differences between the HSD and NSD groups within the (†) GR or (#) wild-type rats.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

With modern day treatments, long remissions are often achieved both in front-line and relapsed setting.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "With", "modern", "day", "treatments", ",", "long", ...

PMC11587541

Firstly, the small sample size could compromise the generalizability of the findings due to limited representation of the diverse population.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Firstly", ",", "t...

PMC11185260

Furthermore, Western blot analysis of BT-12 cells treated with scL-SMARCB1 showed distinct bands of the exogenous SMARCB1 protein at 44kDa at all time points (Figure 2C).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11627133

N=50 cells) of HEK293T cells expressing H2B‐GFP from confocal images as shown in D).

[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "N=50", "cells", ")", "of", "HEK...

PMC11228511

Western blot comparing the expression of lamin A and progerin in the mouse aorta and in cultured SMCs expressing Dox-inducible constructs for human (hu)-prelamin A and hu-progerin.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

TRAEs of any grade occurred ≥20% of patients were neutropenia (36.8%), leukopenia (31.5%), ALT elevation (31.5%), AST elevation (26.3%), hyperphosphatemia (21%), hyperuricemia (21%), and diarrhea (21%).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC3813807

These data indicate that miRNAs are involved in gastric carcinogenesis via a variety of patterns and pathways and that it may be possible to manipulate miRNA to achieve therapeutic effects.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11599565

For instance, MDA-MB-231 PGCCs activate programs resembling osteogenesis, chondrogenesis and adipose differentiation after culturing in differentiation media.

[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "instance", ",", "...

PMC9351137

A Total CRS amount assessed by Western blotting in RNAi-treated and mock-treated cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "Total", "CRS", "amount", "assessed", "by", "Western", "blotting", ...

PMC9985266

Aberrant IL-27 expression was observed in BLM-induced mouse lung tissues, and the use of IL-27 attenuated mouse lung tissue fibrosis.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aberrant", "IL-27", ...

PMC11536589

The expression levels of MGST1 in parental PDAC cells and MRTX1133-resistant PDAC cells. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "expression", "levels", "of", "MGST1", "in", "parental", "...

PMC9581083

Clinical evidence continues to grow in support of JSHD as an adjuvant treatment in COVID-19 infection (Shibu et al., 2022).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Clinica...

PMC11763111

Most studies assessing the efficacy of CAR-T cell therapy have employed NSG mice to establish cell line-derived xenograft (CDXs) models .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Most", "stud...

PMC9927933

Interestingly, the levels of DEPTOR, like all other proteins tested and known to fluctuate with the cell cycle, indeed fluctuated during cell cycle progression.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

The mortality in the ICU was 88% (22 pts).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "mortality", "in", "the", "ICU", "was", "88", "%", "(", "22", ...

PMC11682224

M2-type macrophages normally have anti-inflammatory and tissue-repair-promoting functions, but in the tumour environment they mainly promote tumour growth, angiogenesis, stromal remodelling, and immune escape.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

In patients, clonal T cell expansion and activation, IFN-g and TNF-α upregulation, and Fas mediated cell death, lead to severe BM destruction and the development of AA.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10522430

In 6-well plates, a total of 1 × 10 HeLa cells were subjected to incubation with G. applanatum extract and medium under 5% CO2 at 37°C overnight.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC4839679

n = 3 independent biological replicate experiments.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "n", "=", "3", "independent", "biological", "replicate", "experiments", "." ] } ]

PMC11013014

172 °C (degradation).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "172", "°", "C", "(", "degradation", ")", "." ] } ]

PMC8097906

Statistically significant differences were compared using the unpaired Student’s t-test.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Statistically", "significant", "differences", "were", "compared", "using", "the", "unpaired", ...

PMC11549062

Carotid VSMCs were plated in a six‐well plate and subjected to transfection and treatment.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Carotid", "VSMCs", "were", "plated", "in", "a", "six‐well", "pla...

PMC9429973

Accelerated CLL/SLL (aCLL/SLL) is pathologically defined as a highly proliferative form of CLL/SLL (either expanded proliferation center or Ki-67>40%).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC6617630

Based on the MYC, BCL2, and BCL6 rearrangements, DLBCL cell lines were determined to fall into either wild-type MYC (WT-MYC) seen in HBL-1 and U2932 cell lines; single MYC rearrangement with immunoglobulin commonly referred to as single hit (MYC/IG; SH) seen in Raji and Ramos Burkitt lymphoma cell lines; MYC rearrangement with BCL2 gene (MYC/BCL2; DHL) seen in OCILY1, OCILY10, SUDHL2, and DOHH2 cell lines; or MYC rearrangements with both BCL2 and BCL6 genes (MYC/BCL2/BCL6; THL) seen in only VAL cell line (Table 1).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC7685376

Relative expression levels of MCM2, MCM3, and MCM4 in 369 HCC tissues and 160 normal tissues got form GEPIA database. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Relativ...

PMC11351758

Then, the slides were stained for 30 min.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Then", ",", "the", "slides", "were", "stained", "for", "30", "min", "." ] } ]

PMC11696576

All box and whisker plots show the mean (center line), stdev (box), and min and max values (whiskers) from 4 biological replicates.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9024365

Next, we looked at changes in the mean area of GluA1 clusters as a result of chemical-LTP.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Next", ",", "we", "looked", "at", ...

PMC11594074

After incubation for 72 h, 20 µL of 0.01% resazurin solution was added to each well and again incubated.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "incubation", ...

PMC10197932

CD69 also interacts with LAT-1 (amino acid transporter, tryptophan transporter) 22 suggesting its functional role in switching metabolism during activation.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CD69", ...

PMC3019555

HIF-1α, the oxygen-regulated subunit of HIF-1, is found overexpressed in >70% of all human tumors, and its expression is correlated with poor prognosis and resistance to therapy.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10380508

MTT assays were carried out using the Cell Proliferation Kit (Roche Applied Science, Penzberg, Bavaria, Germany) at selected time-points, following the manufacturer’s instructions.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Eight comprehensive geriatric assessment (CGA) domains were analyzed in 135 of these patients to screen items most closely associated with the outcomes, including grade ≥ 3 adverse events (AEs), treatment discontinuation, TTP, and OS.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11711871

All animals were housed in a humidity- (< 40%) and temperature-controlled room (23 ± 1 °C) with an automatic 12-h light/dark cycle (light: 7 am to 7 pm) in ventilated cages with free access to food (normal salt diet, NSD; 0.25% Na and 0.70% K diet; Provimi Kliba AG; number 3242-XP18, Switzerland, hereinafter referred to as the standard diet) and tap water in an approved animal care facility of the University of Lausanne.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11643491

The ability to selectively target specific cell types by exploiting their unique mechanical properties can also be valuable for the development of more precise immunotherapies, where particle shape may influence the interaction between immune cells and nanoparticles designed for vaccination or cancer immunotherapy.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11487720

A COS7 cells were UV irradiated (480 mJ/cm) and cold shocked for indicated times, which led to rapid downregulation of cortactin and α-tubulin.

[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10996034

At the same time, in order to investigate the association of Taxol resistance of EOC with disease stage, the associations between MMP1, ZYX and UNC5C, and the disease stage of EOC (stage II, III and IV) were examined.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Differences were considered statistically significant at p<0.05.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Differences", "were", "considered", "statistically", "significant", "at", "p<0.05", "." ] } ]

PMC8978939

The crystal structure of a human VBC: HIF-1α complex PDB 4AJY (X-Ray diffraction, 1.73 Å resolution) was used as starting structure (41).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC6650823

Thi et al. tried to discover novel multi-target agents with better anti-tumor activities than celecoxib.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thi", "et", "al.", "tried", "to", "discover", "novel", ...

PMC11462673

Additionally, visualization of liver and spleen samples of mice using fluorescence imaging indicated a substantial reduction in tumor burden within the LDB1 knockdown group when compared to the control group (Fig. 3C).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

No serious adverse event (SAE) occurred.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "No", "serious", "adverse", "event", "(", "SAE", ")", "occurred", "." ] } ]

PMC11679033

Combined exposure to both compounds resulted in a lowering of primary and cytogenetic DNA damage caused by CIT.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Combined", "exposure", "to", "both", "...

PMC11697065

Unconventional biological drugs with complex structures and processing requirements are particularly problematic.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Unconventional", "biological", "drugs", "with", "complex", "structures", "and", "proce...

PMC4270159

Meta-analysis of original and replication attempt effect sizes:We will plot the replication data (mean and 95% confidence interval) and will include the original data point, calculated directly from the representative image in Figure 2C, as a single point on the same plot for comparison.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9516401

Phenolic content of in P. vulgaris, C. colocynthis, P. oleracea, A. cepa, and C. verum extract The content of total phenols in the extract of A. cepa, C. colocynthis, P. vulgaris, P. oleracea and C. verum was 28, 40, 22, 57, and 372 mg gallic acid equivalent per gram of the crude extract, respectively.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11534035

Strong evidence of this function has been discovered in the realm of gynecological oncology, specifically in breast, ovarian, and most recently also in VCs (10,14,19-22).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11026382

These discrepancies between true and effective kcat could be addressed in future work by including additional high-throughput assay data on stability or abundance to tease apart mutational effects on catalysis from stability and abundance.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11024707

ASD is a phenotypically heterogeneous clinical spectrum, and affected individuals are influenced at different levels.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ASD", "is", "a", "phenotypically", "heterogeneous", "c...

PMC11742290

Their research showed that LGR5 + cells contributed to the maintenance and regeneration of the epithelial lining in both the ovary and the fallopian tube .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...

PMC11752740

Additionally, a notable decrease was found between the combined treatment at 48 h and that at 24 h (denoted with †), indicating that the drug-extract combination’s efficacy improves over time.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11627133

In these experiments, we utilized the single‐stranded DNA aptamer AS1411, which targets nucleolin, a highly abundant protein found in the nucleolus.[ , ]

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10890307

Calu-1 had the highest qP Lactate when it was grown using glucose at a pH of 7.2 under normoxia (Glc/pH7.2/N); MRC-5 had the highest qP Lactate in comparison with the other tumor cell lines when it was grown in Glc/pH7.2/H, glucose-containing media at a pH of 6.2 and under normoxia (Glc/pH6.2/N), and glucose-containing media at a pH of 6.2 and under hypoxia (Glc/pH6.2/H) (Table 3 and Table 4).

[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "...

PMC9622879

By using the variable s(t), our optimization problem can be transformed into28[12pt] $$ min _^ C_(t), $$∑t=1TCCom(t),subject to:29[12pt] $$&C_(t) ( _^E_^(t) - _^E_^(t)) P_(t) - M (1-s(t)) $$(t)≥∑i=1NEi,Combuy(t)-∑i=1NEi,Comsell(t)·PMG(t)-M·(1-s(t))30[12pt] $$&C_(t) ( _^E_^(t) - _^E_^(t)) P_(t) + M (1-s(t)) $$(t)≤∑i=1NEi,Combuy(t)-∑i=1NEi,Comsell(t)·PMG(t)+M·(1-s(t))31[12pt] $$&C_(t) ( _^E_^(t) - _^E_^(t)) P_(t) - M s(t) $$(t)≥∑i=1NEi,Combuy(t)-∑i=1NEi,Comsell(t)·α·PMG(t)-M·s(t)32[12pt] $$&C_(t) ( _^E_^(t) - _^E_^(t)) P_(t) + M s(t) $$(t)≤∑i=1NEi,Combuy(t)-∑i=1NEi,Comsell(t)·α·PMG(t)+M·s(t)and33[12pt] $$ (1)(18), (24), (26), (27), (29)(32).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11216402

Three hundred fifty-six tumor (TCGA-STAD) and 32 normal stomach (TCGA-Normal) samples were initially obtained.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Three", "hundred", "fifty-six", "tumor", ...

PMC11040965

However, the molecular events that link CD28 activation to proteasome subunit downregulation have not been determined.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "the", "molecular", "events", ...

PMC9429973

No discontinuations due to RG6234-related AEs occurred.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "No", "discontinuations", "due", "to", "RG6234-related", "AEs", "occurred", "." ] } ]

PMC11349530

According to the studies that evaluated the ability of tumor cells to produce various cytokines, VEGF is one of the most intensively produced cytokines by various tumor cells (76–78).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11423992

A11138-03, Gibco).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A11138", "-", "03", ",", "Gibco", ")", "." ] } ]

PMC11599565

Panel A: expression of cardinal transcription factors defining a neuronal phenotype and structural proteins.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Panel", "A", ":", "expression", "of", "cardinal", "transcri...

PMC9817179

D–F) Quantification of puncta parameters after fixation.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "D", "–", "F", ")", "Quantification", "of", "puncta", "parameters", "after", "fixation", "....

PMC11139449

FlowJo (version 7.6) software was used to examine the data.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "FlowJo", "(", "version", "7.6", ")", "software", "was", "used", "to", "exa...

PMC11545737

YopE and YopT are Rho-modifying enzymes, YopE is a GTPase-activating protein while YopT is a protease.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "YopE", "and", "YopT", "are", "Rho-modifying", ...

PMC9592219

In this study, we aimed to explore the TOP2A tumor-promoting effects and elucidate whether TOP2A regulates the activity of YAP1 in the Hippo signaling pathway by binding to β-catenin to exert biological effects.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC5535901

Our data show novel insights into the mechanisms underlying induction of pro-inflammatory cytokine release by pharmacological concentrations of I3C and DIM, an effect negligible under physiological conditions.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11317131

PE uses a fusion protein consisting of a Cas9 nickase and reverse transcriptase called PE5, as well as a prime editing guide RNA (pegRNA) (31).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11307990

Taken together, this study provides a promising candidate platform for the delivery of cell membrane receptor inhibitors in anticancer therapy.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Taken", "together", ...

PMC10877303

Molecular docking analysis facilitated the selection of the three best compounds based on their binding energy, namely Kihadanin B, Robustaflavone, and 3-beta-O-(trans-p-Coumaroyl)maslinic acid.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...

PMC11770130

To investigate whether the changes in lipolysis were due to the cell-autonomous effects of the NTS-NTSR2 signaling, we treated the primary adipocytes derived from SVF with recombinant NTS peptides.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC3813807

These observations indicate that TNFAIP1 is negatively regulated by miR-373.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "observations", "indicate", "that", "TNFAIP1", "is", "negatively", "regulated", "by", "m...

PMC10810426

These findings suggest that simple retroviruses, like the complex retrovirus HIV, gain nuclear entry by traversing the nuclear pore complex in non-mitotic cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...

PMC9429973

Overall, the median NAB was 2 with no significant difference between the two COO subgroups (Kruskal wallis chi-squared 0.63, p= 0.42).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...

PMC4485786

Nuclei were stained with Yopro (1:2000; Invitrogen, Germany) for 5 min before mounting the slides with Mowiol (Hoechst, Germany).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...

PMC8382973

The pH 4.4 or pH 7.4 of both gels was similar to that of the vaginal and rectal environment.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "pH", "4.4", "or", "p...

PMC8143558

For plants such as legumes, biotic factors such as the presence of symbiotic mycorrhizal fungi enhance production of higher quantities of better-quality phytochemicals .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC9031474

Proper target identification will lay a solid basis for future lead compound discovery and candidate selection for preclinical and clinical development.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Proper", "target", ...

PMC11679326

Another representative C1qDC protein in marine invertebrates OXYL from marine star Anneissia japonica can bind to N-acetyllactosamine (LacNAc) type 2 (Galβ1,4GlcNAc) but does not recognize LacNAc type 1 (Galβ1,3GlcNAc), and it could recognize breast cancer BT-474, MCF-7, and T47D cells without exhibiting cytotoxicity .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11680578

β-actin and PPAR-α were used as housekeeping genes.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "β-actin", "and", "PPAR-α", "were", "used", "as", "housekeeping", "genes", "." ] } ]

PMC9436459

There are only four compounds in type E-II MDAAs, two (124 and 125) of which feature the C-6 dehydroprenyl and two (126 and 127) feature the C-8 dehydroprenyl.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11144200

B The CD8 T cells above were stained with CFSE-conjugated anti-CD25 or anti-CD69 or CD62L mAb and analyzed by flow cytometry for activation.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "B", ...

PMC10956161

The correlation between the PRDX6 gene and these 20 genes was analysed.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "correlation", "between", "the", "PRDX6", "gene", "and", "these", "20", ...

PMC11666785

Multiphoton variant of super-resolution microscopy has enabled better penetration depths suitable for scattering medium such as tissue.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Multiphoton", "variant", "of", "super-resolution", ...

PMC10587429

Paraformaldehyde (PFA, 158127, Millipore Sigma, Burlington, MA). -

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Paraformaldehyde", "(", "PFA", ",", "158127", ",", "Millipore", ...

PMC9429973

Targeted sequencing was performed on DNA samples using the TruSight Myeloid Sequencing Panel.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Targeted", "sequencing", "was", "performed", "on", "DNA", "samples", "using...

PMC11622247

In spite of challenges with the amount of probes delivered into T cells, the evidence suggests that the probes engage with their target.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...