Datasets:
OTAR3088
/
BioData-CellLine_annotated

Dataset card Data Studio Files
xet
 Community
1
PMCID
string
Sentences
string
ner
list
PMC9592219
The upregulation of TOP2A, which promoted EMT, is responsible for the promotion of HCC cell invasion and migration.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "upregulation", "of", ...
PMC9429973
According to Figure 1, high AMC group (>0.6×109/L) and low LMR group (<1.8) were associated with poor outcomes.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11476106
These cells display morphological characteristics indicative of neural differentiation, such as rosette formation .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "cells", "display", "morphological", "characteristics", "indicative"...
PMC6114978
Cells were incubated with anti-TAZ and anti-YAP antibody diluted (1:100) in 3% fetal bovine serum at 4°C overnight in a humidity chamber.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
We received 25 of 30 silicone bands from the initial visit (83%) and identified a high prevalence of exposures to multiple chemicals.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973
The Functional Assessment of Cancer Therapy-Bone Marrow Transplant (FACT-BMT) measured QOL.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "Functional", "Assessment", "of", "Cancer", "Therapy-Bone", "Marrow", ...
PMC11653168
In the in vitro experiments, the vehicle control group received a final DMSO concentration of 0.05%, while the 5, 2.5 and 1.25 µM Stattic groups received DMSO concentrations of 0.05, 0.025 and 0.0125%, respectively.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10006224
For other experiments, nuclei were isolated before sonication.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "other", "experiments", ",", "nuclei", "were", "isolated", "before", "sonication", "." ] } ]
PMC9429973
Image: Summary/Conclusion: These data suggest that the PT-Cy platform is an effective GVHD prophylaxis for the 10/10 UD allo-HSCT patients.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Image", ":",...
PMC9429973
Two independent reviewers screened titles and abstracts based on predefined inclusion and exclusion criteria, including reporting of relevant population data and at least one outcome of interest.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11739504
In vivo experimental procedures were conducted with the review and approval of the IACUC at Sookmyung Women’s University, Seoul, Republic of Korea.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC7090062
In addition, flow cytometric analysis indicated a clear increase in apoptosis in GIST cells following miR-30a re-expression, whereas miR-30a inhibition had the opposite effects (Fig. 3d).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Murine studies were carried out in 8-14-week-old C57BL/6 mice.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "Murine", "studies", "were", "carried", "out", "in", "8", "-", "14-week-old", ...
PMC3035438
Concentration of chicken IgM in culture supernatants determined by quantitative ELISA.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Concentration", "of", "chicken", "IgM", "in", "culture", "supernatants", "determined", "by"...
PMC9429973
However, both NTDT and TDT patients had poorer HRQoL than healthy controls (83.45 [15.6]); P<0.0001).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",...
PMC9429973
Aims: Our study aims to clarify the role of JAK2 V617F mutation in MPN in a large cohort of Bulgarian patients with previous medical history of vascular incidents.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11486946
Lasers at wavelengths of 488 nm (OBIS 488LS, Coherent, USA) were used to excite GFP fused with EGFR.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Lasers", "at...
PMC5925824
Antibody treatment (indicated by red arrows), either human IgG or LY3300054, was delivered by intra-peritoneal injection in each case at 10 mg/kg.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11697065
Routine culture for all cell lines was performed at 36.5°C in vented, non-baffled Erlenmeyer flasks (Corning, Amsterdam, The Netherlands), in 5 % CO2 maintained at 140 rpm.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
M. Fournier, J. Msihid, A. Willemze, F. Laredo, R. Pulikottil-Jacob Sanofi, Chilly-Mazarin, France; Sanofi, Amsterdam, Netherlands; Sanofi, São Paulo, Brazil; Rare Disease, Health Economics and Value Assessment, Sanofi, Berkshire, United Kingdom Background: Acid Sphingomyelinase Deficiency (ASMD) is an ultra-rare, lysosomal storage disease with a broad spectrum of clinical manifestations.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7823217
In order to recapitulate the microenvironment of physiological stroma of tumor tissue within bioprinted constructs, preferably, patient-derived primary cells from the tumor tissue should be isolated, cultured and mixed with the hydrogel to generate the bioink rather than using biobanked primary cells and cell line.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5941560
Genes with damaging mutations in the Jurkat cell line are involved in T-cell receptor signaling (PTEN, INPP5D, CTLA4, and SYK), maintenance of genome stability (TP53, BAX, and MSH2), and O-linked glycosylation (C1GALT1C1).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11411131
Expression of multi-Sec selP mutants.
[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Expression", "of", "multi-Sec", "selP", "mutants", "." ] } ]
PMC11566417
Previous studies have shown that the bioactive secretomes of various cell types can be stored through ultra-freezing (-80 °C) or lyophilization for up to 6 months without significant loss in bioactivity, both in the context of protein- and extracellular vesicle-mediated functional properties [127–131].
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11609529
To assess the effect of YM depletion on tumor growth in vivo, we generated ovarian cancer ES-2 cells that express luciferase (ES-2-luc) and subsequently transduced them with pLKO.1 lentiviruses carrying either shCtl or shM2-3 targeting YM/MAML2.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "B-CellLine", "O", "...
PMC9874064
Fig. 4NP-Pt-USP1i increased DNA damage in vitro.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fig.", "4NP-Pt-USP1i", "increased", "DNA", "damage", "in", "vitro", "." ] } ]
PMC11794568
CRIP1 is differentially enriched in mitochondrial biogenesis (A), mitochondrial translation (B), mitochondrial protein import (C), mitochondrial complex I assembly model oxphos system (D), respiratory electron transport (E), and mitochondrial electron transport chain oxphos system (F).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11655498
These EBV-encoded proteins are responsible for regulating virus assembly and progeny production by modulating various cellular factors.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "EBV-encoded", "proteins", "are", "respon...
PMC11754784
During the input computing layer, the DNA nano-claw works as a signal convertor of DNP by equipping with one or more aptamer-based specific recognition toes.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC10578720
The significantly different metabolite classes between samples included carboxylic acids and their derivatives, dinucleotides, flavin nucleotides, keto acids and their derivatives, organic phosphoric acids and their derivatives, and purine nucleotides (Figure 2E).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11635519
GPCRs have become the primary pharmaceutical targets for drug discovery, covering more than 30% of FDA-approved marketed drugs due to their substantial involvement in human pathophysiology and pharmacological tractability.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10890055
The cultivation conditions should therefore be chosen with caution.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cultivation", "conditions", "should", "therefore", "be", "chosen", "with", "caution", "." ] } ...
PMC9429973
The 1-year PFS and OS were 85.6% and 93.3%, respectively.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "1-year", "PFS", "and", "OS", "were", "85.6", "%", "and", ...
PMC11740907
The implementation of these models was carried out utilizing the DDsolver program.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "implementation", "of", "these", "models", "was", "carried", "out", "utili...
PMC11477621
H NMR (400 MHz, CDCl3) δ 6.91–6.84 (overlap, 2H), 6.03 (t, J = 3.3 Hz, 1H), 4.20 (t, J = 7.2 Hz, 2H), 2.32 (s, 3H), 2.12 (t, J = 7.4 Hz, 2H), 1.99–1.89 (m, 2H).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8097906
Their anti-cancer potential was screened on the human and established RMA cell line RH-30 by cell viability assays (Fig. 1) and subsequently examined with assays to analyze the ability for cell migration, invasion and anchorage-independent colony formation (Fig. 2).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC7802142
c Western blotting and d quantitative analyses of C-myc and Cyclin D1 in cells were performed 48 h after treatment.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "c", "Western", "blotting", ...
PMC11190062
RNeasy mini kit was used to isolate total RNA (Qiagen, Hilden, Germany) before cDNA was synthesized with a High Capacity RNA-to-cDNA kit (Applied Biosystems, Carlsbad, CA, USA).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10545062
An underbody warmer maintained core body temperature between 37°C and 39°C.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "An", "underbody", "warmer", "maintained", "core", "body", "...
PMC11638255
Data minima and maxima values are as indicated, the median (solid line), and the first and third quartiles (dotted horizontal lines).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11774251
There were 91 significantly up-regulated genes and 107 significantly down-regulated genes in the Tan-I group relative to those in vehicle-treated mice (Figure 2A, P-value ≤ 0.05 and fold-change ≥ 2).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11423992
However, it does not confer a curative effect.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "it", "does", "not", "confer", "a", "curative", "effect", "." ] } ]
PMC11055443
Caco-2 cells and 2.
[ { "tags": [ "B-CellLine", "O", "O", "O", "O" ], "tokens": [ "Caco-2", "cells", "and", "2", "." ] } ]
PMC11528603
Further evaluation indicated that AM could initiate apoptosis in this cell line via activation of caspase family (i.e., caspase-3, -7 and -8).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9100622
We observed decreased cell proliferation characterized by a slowdown of the S-phase.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "observed", "decreased", "cell", "proliferation", "characterized", "by", "a", ...
PMC10705095
HBQ1 coding sequence: 5′-AGA TCT ATG GCG CTG TCC GCG-3′ and 5′-GAA TTC TCA GCG GTA CTC GGA AAC CA-3′. The PCR products were digested with the corresponding enzymes and cloned into the pLenti6/V5 vector.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11252033
Aliquots of total protein (30 μg) were electrophoresed on 8%–12% (v/v) SDS-PAGE gel (Thermo Fischer Scientific, Milan, Italy), transferred onto nitrocellulose membranes (Bio-Rad, CA, United States) and probed overnight at 4 °C with primary antibodies against CryZ (2A9DD1, Abcam, United States), Bcl-2 (clone 100, Thermo Fisher Scientific), Bcl-xl (SC-8392, Santa Cruz Biotechnologies) and beta-actin (β-actin Thermo Fisher Scientific).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10854447
However, the ligand loses H-bond interaction with the key amino acid residue Met769 compared with the H-bond formed by the quinazoline nitrogen of Erlotinib (3.56 Å) (Figure 5E, F).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11672617
It can be concluded that the regulation of free oxygen species levels in cancer cells is of great importance for the physiology, growth, and survival of tumor cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7192625
For this reason, we have provided additional tools to more carefully dissect each feature or combination of features in the context of 3D contacts.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11693599
Furthermore, increased expression levels of CD109 in ovarian cancer spheroids were confirmed by immunofluorescence staining (Fig. 1D).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Furthermore", ",", "increase...
PMC11591794
In our study, GA and DOX were observed to induce apoptosis according to both MTT analysis and NucBlue staining method results.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "our", ...
PMC11604830
While, at 4 and 24 h p. i., an increasing accumulation of nanoparticles can be observed in the inflamed areas, recognizable at the LPS injection site due to the surgical action, as well as in the striatal areas where inflammation was induced.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11742231
This process can be done using a weighted sum operation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "process", "can", "be", "done", "using", "a", "weighted", "sum", "operation", "." ...
PMC11621493
To further explore the role of Ca in regulating membrane interaction, we investigated the association of PLA2G4D with cytosolic and membrane fractions in the absence and presence of CaCl2.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7987994
However, for degradable materials, these ratios are inappropriate.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "for", "degradable", "materials", ",", "these", "ratios", "are", "inappropriate",...
PMC11301242
Middle: SV profile, with SVs illustrated as arcs; breakpoints are represented by black points, and those corresponding to interchromosomal SVs are depicted as colored points.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11656657
Schematic representation of PBMC co-cultured with OS tumor cells (A) or with OS conditioned medium (CM) for 72 h (B).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10237474
Unlike mammalian cells, insect cells have simpler glycosylation patterns with shorter N-glycans and little sialylation .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Unlike", "mammalian", "cells", ",", "insect", "cells",...
PMC9429973
10 patients (25%) aged ≥80 years.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "10", "patients", "(", "25", "%", ")", "aged", "≥80", "years", "." ] } ]
PMC11464982
The food enzyme endonuclease was tested in a basic battery of in vitro genotoxicity studies.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "food", "enzyme", "endonuclease", "was", "tested", "i...
PMC10452486
Indeed, mAb45 resulted in reduced soluble TNF and decreased CD4+ T cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Indeed", ",", "mAb45", "resulted", "in", "reduced", "soluble", "...
PMC11770130
The digested solution was filtered through a 100-µm cell strainer, centrifuged at 800 rpm for 5 min and the red blood cells were lysed by ACK buffer (Cat# A10492-01, Gibco).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11300639
By delving more deeply into the interactions between TSC1 and CDK4, we aimed to elucidate the significance of this mechanism in the development of ccRCC, providing a more profound understanding for the development of novel therapeutic strategies in the future.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11592008
Additionally, several keratinocyte cell lines have been generated by immortalization through the ectopic expression of human telomerase (hTERT) , simian virus40 large antigen (SV40) , and cyclin-dependent kinase 4 (Cdk4) .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10891340
The involvement of autophagy in mitochondrial clearance in non-developmental environments has been demonstrated in yeast (Zhang et al., 2007; Kanki et al., 2009; Okamoto et al., 2009) and in some mammalian experiments (Hamacher-Brady et al., 2007; Kim et al., 2007).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5963610
These antibodies are mostly of the IgG isotype and could last for several months in circulation .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "antibodies", "are", "mostly", "of", "the", ...
PMC7917457
The linearized VALO-D102 viral genome was transfected into A549 cells using the Effectene transfection reagent (QIAGEN), resulting in the production of viable VPs.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11190538
Thus, the work aims to produce crude phycocyanin (C-PC), define it, and investigate its pharmacological effects before warping it in a nanophytosome.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11026382
Color coding is identical to panel (b).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Color", "coding", "is", "identical", "to", "panel", "(", "b", ")", "." ] } ]
PMC7802142
DPCs were transfected with 100 nM antisense miRNAs in 6-well plates with lipo2000 (Life Technologies) according to manufacturer’s instructions, followed by ReN-NV treatment 12 h later.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8389560
At the same time, a close spatial relationship between mitochondria and IP3R ER is known .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "At", "the", "same", "time", ",", "a", "close", ...
PMC9429973
There were no cases of WE.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "There", "were", "no", "cases", "of", "WE", "." ] } ]
PMC11790971
In addition, single-cell images corresponding to the dots in the t-SNE plot were sampled and visualized in the same locations.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "addition", ...
PMC9429973
Alterations in the RELs of differentiation markers (SOX9, SPP1, PPARγ) indicate changes in the predisposition of MSCs to differentiation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Alterat...
PMC11774747
Beyond proliferation, different functional improvements were observed secondary to viral triggering.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Beyond", "proliferation", ",", "different", "functional", "improvements", "were", "obs...
PMC11545737
To recognize pathogens, mammalian host cells use a broad array of pattern-recognition receptors (PRRs), which bind either conserved microbial molecules, collectively referred to as pathogen-associated molecular patterns (PAMPs), or host molecules known as damage-associated molecular patterns (DAMPs), which are released from stressed or damaged infected cells .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5916734
The resulting clonal cell line 3B12-86 was able to secrete factor IX in a protein-free medium up to a 6 IU/ml titer under plain batch culturing conditions.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11763126
E Body weights of mice with subcutaneous xenografts.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "E", "Body", "weights", "of", "mice", "with", "subcutaneous", "xenografts", "." ] } ]
PMC10890307
This study did not, however, report the kinetic parameters of these processes, nor did it analyze other conditions such as hypoxia or neutral pH. Liu et al. determined the effect of amino acid restriction on the rates of glucose consumption and lactate production by DU145 and PC3 prostate cancer cells using Met-, Tyr/Phe-, or Gln-medium .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11518994
For the first time, we describe a novel damaging frameshift PAX5 germline variant in two Italian siblings with BCP- ALL, associated with the same somatic PAX5 P80R variant in both cases, suggesting a possible novel mechanism for promoting leukemogenesis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
The results of this study are descriptive, and no formal hypotheses was pre-specified.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "results", "of", "this", "study", "are", "descriptive", ",...
PMC11730000
Advansta, San Jose, USA).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Advansta", ",", "San", "Jose", ",", "USA", ")", "." ] } ]
PMC10813895
Methylated DNA is believed to be the default state in the genome, rather than unmethylated DNA because CpG sites are protected from methylation due to occupation by transcription factors.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11441402
The MTT assay lost linearity at high cell density for both adherent cell lines.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "MTT", "assay", "lost", "linearity", "at", "high", "cell",...
PMC11762280
Furthermore, impaired mitochondrial DNA (mtDNA) is another endogenous ligand that activates ZBP1 .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Furthermore", ",", "impaired", "mitochondrial", "DNA", "(", ...
PMC7342409
1.
[ { "tags": [ "O", "O" ], "tokens": [ "1", "." ] } ]
PMC11633763
After 5 weeks, mice were dissected and the tumours were weighed and photographed.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "5", "weeks", ",", "mice", "were", "dissected", "and", ...
PMC10882807
The cells were cultured in suitable medium containing 10% fetal bovine serum (Lonsera, USA) at 37 °C with 5% CO2.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11679892
Comparative analyses with healthy cell lines and different cancer cell lines (such as HeLa or MCF-7) are needed to determine whether apoptosis is specifically induced in cancer cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC9429973
In addition, poor clinical status and advanced disease may impact the choice of not using triplet regimens upfront.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "addition", ",", "poor", ...
PMC11409031
Green indicates deletion frequency, while red dots represent amplification frequency. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Green", "indicates", "deletion", "frequency", ",", "while", "red", "dots", "repr...
PMC11474209
Optical sensor systems have a lower risk of producing explosives in a hazardous environment than electrical transmission systems and are thus clearer from electromagnetic disturbance.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC6643347
Dendritic cells are prototypical antigen-presenting cells with an extraordinary capacity for recognizing and processing antigens .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Dendritic", "cells", "are", "prototypical", "antigen-presenting", ...
PMC11725127
Relative mRNA levels of USP2 in PBMC and primary myeloma cells (n = 6). (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Relative", "mRNA", "levels", "of", "USP2", ...
PMC11774251
H&E staining of the skin lesions (Figure 1H) showed that Tan-I-treated mice displayed significantly reduced epidermal acanthosis (Figure 1I) and reduced dermal inflammatory infiltrates (Figure 1J) in histopathology, compared with vehicle-treated mice.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Moreover, BTKi can alter the tumor microenvironment and downregulate IL-6 level to improve the efficacy and safety of CART19 cell therapy.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", "...
PMC11711063
Abbreviations: BM, basal membrane; ECM, extracellular matrix.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Abbreviations", ":", "BM", ",", "basal", "membrane", ";", "ECM", ",", "extracellular"...
PMC11745600
Insulin sensitivity of Ins1 and Ins1 NOD/Shi-scid IL2rγc (NOG) mice.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Insulin", "sensitivity", "of", "Ins1", "and", "Ins1", "NOD/Shi-scid", "IL2rγc", ...
PMC9429973
53 adult (≥18 years old), complement-inhibitor naïve (no prior eculizumab/ravulizumab) patients with LDH ≥1.5x the upper limit of normal (ULN) (≥339 U/L) and Hb below the lower limits of normal (LLN) (males: ≤13.6 g/dL; females: ≤12.0 g/dL), were enrolled.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...