Datasets:
OTAR3088
/
BioData-CellLine_annotated

Dataset card Data Studio Files
xet
 Community
1
PMCID
string
Sentences
string
ner
list
PMC11653168
Additionally, the stability of p-STAT3 and the rate of dephosphorylation may vary among different cell lines.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "the", "stability", "of", ...
PMC11696576
b Synthesis of inhibitors.
[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "b", "Synthesis", "of", "inhibitors", "." ] } ]
PMC11271278
D HiChIP, H3K27ac ChIP-seq (derived from HiChIP reads), and copy number profiles at DNA segments of the MYC ecDNA in NCIH2170 cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", ...
PMC9895440
PinAPL-py was then used to align, control for quality, and count guides with the 5’ adapter ATTTTAACTTGCTATTTCTAGCTCTAAAAC.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "PinAPL-py", "was", "then", ...
PMC4443654
The same pattern was not seen for enhancers shared between two or more of the cell types under study.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "same", "pattern", "was", ...
PMC8873393
In all, TC-NER is not merely a mechanism that would recruit the DNA repair factors to recognize and remove DNA lesions.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "all", ...
PMC11742431
Fluorescence effects of RL, RVL, and R14L proteins on UMUC‐3‐EGFP cells by fluorescence inversion microscopy.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fluorescence", "effects", "of", "RL", ",...
PMC8567602
A, Euclidean distance of samples heat map of nonhierarchical clustering of transcriptomes from tumors in mice bearing hSS2, homozygosity for Smarcb1-floxed, or combination genotypes following Myf5Cre or TATCre induction.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5173112
x100 in six different fields per filter). (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "x100", "in", "six", "different", "fields", "per", "filter", ")", ".", "(" ] } ]
PMC6799808
In addition, mTORC1 is negatively regulated by AMPK (AMP-activated protein kinase).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "addition", ",", "mTORC1", "is", "negatively", "regulated", ...
PMC11742864
Although the precise anti-tumor mechanism has not been elucidated yet, ω-3 LCPUFAs are often used in the nutritional treatment of patients with cancer due to their ability to significantly improve patient’s nutritional status, increase the sensitivity of tumor cells to treatments, and alleviate cancer-related complications.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10253973
The binding energies were estimated using the molecular mechanics/Poisson–Boltzmann surface area method .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "binding", "energies", "were", "estimated", "using", "the", ...
PMC9429973
Small studies suggest synergy between I and V, as I+V results in MRD negativity in many patients (pts).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Small", "studies", ...
PMC11277157
For transfection, we used Lipofectamine 2000 (Lipo2000; Invitrogen, Cat # 11668019, Carlsbad, CA, USA) in cells at 40–50% confluency according to the manufacturer’s instructions.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11752740
This pronounced synergy in SK-BR3 cells aligns with CFZ’s role as a proteasome inhibitor, which disrupts protein degradation in cancer cells, leading to increased intracellular stress and enhanced apoptosis .
[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11742290
RING finger protein 43 (RNF43) and its homolog Zinc/Ring finger protein 3 (ZNRF3) negatively regulate WNT pathway by internalizing and degrading FZD and LRP5/6. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
First relapse treatment data was available for 36 patients.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "First", "relapse", "treatment", "data", "was", "available", "for", "36", "patients", "." ] } ]
PMC11463018
Data are the mean ± SD of three independent experiments: ***p < 0.001 ****p < 0.0001 compared to the ctrl group.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11756514
The presence of several S. aureus binding CTLs is an example of redundancy in the innate immune system since they can all recognize S. aureus and even inhibit each other’s binding if co-existing.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC2118063
Protein from the mouse NFS-202 cell line or human tonsillar B cells was cross-linked to DNA using formaldehyde, and immunoprecipitations were performed with anti-IRF8 or control antibodies.
[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Cox proportional hazard models showed that patients with RDW-SD >50.50fl at diagnosis were significantly associated with poor overall survival (OS) (HR = 5.22, CI = 1.50-18.21, P=0.010).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8170755
The predominant form of lung cancer is non-small cell lung cancer (NSCLC), accounting for about 85% of all lung cancer cases (2).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9516401
Subsequently, RNAs were reverse-transcribed using the cDNA synthesis kit (Parstoos, Iran) using the Light-Cycler 96 real-time PCR system (Roche Applied Science, USA).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7961460
With 79% of residues modelled at >90% confidence, the 3D-structure showed the presence of many alpha-helix as secondary structures (see Supplementary Figure S1C), which are typical of coiled coil domain proteins.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11740207
It also plays a role in the formation of immunological multinucleated giant cells (Palovuori et al., 2004; Erenpreisa et al., 2014; Platt and Cascalho, 2019; Dörnen et al., 2020; Vainshelbaum et al., 2022; Vinogradov and Anatskaya, 2023).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC2193049
The CTL line LAU 198 NS (normal stimulation) specific for peptide MAGE-3271–279 was established by stimulating CD8-enriched cells from a LAU 198 melanoma patient with peptide-pulsed, autologous PBL as described (18).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Secondary outcomes were grade 3-4 neutropenia, treatment discontinuation (TD), serious adverse events (SAE) and fatal adverse events (FAE).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11777207
Skin-derived DCs were identified in the dLN as CD11cMHC class II cells that were KikRed (fig. S3A).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Skin-derived", "DCs", "were", "id...
PMC11731161
Cells were then resuspended in 100 µl of 1 × binding buffer, followed by the addition of 5 µl of Annexin V-FITC (BD Biosciences, USA) and 5 µl of propidium iodide (PI) (BD Biosciences, USA).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Gender or race did not modify these associations.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Gender", "or", "race", "did", "not", "modify", "these", "associations", "." ] } ]
PMC11506670
The impact of the novel NRAS mutants—G48C, Q43K, and E37K—on cytoskeletal organization was assessed via actin staining with Alexa Fluor™ 488-conjugated phalloidin (Invitrogen).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Results: In the cohort defined by MD Anderson criteria, PSM analysis showed that patients receiving initial 2G-TKI (n = 89) had higher probability of achieving a CCyR (p = 0.01), MMR (p = 0.04) and MR (p = 0.004) than those receiving imatinib (n = 156), however, probabilities of FFS, PFS and survival were similar.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10914904
For instance, exposure of human keratinocytes to UV-B radiation can induce inflammation by upregulating cyclooxygenase 2 (COX2) and TNF-α and activating matrix metalloproteinase-9 (MMP9), potentially leading to premature skin aging .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8164677
In this investigation, combination of wedelolactone and cisplatin has been found to be more effective/additive in endometrioidal non serous cisplatin resistant ovarian cancer cell line A2780 than in parent cell line A2780, irrespective of any sequence of administration.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine"...
PMC9429973
At baseline, 61% were male and the median age was 60.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "At", "baseline", ",", "61", "%", "were", "male", "and", "the", ...
PMC11726183
We then performed a binding free energy calculation to evaluate the stability of complexes.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "then", "performed", "a", "binding", "free", "energy", "cal...
PMC6684588
The physiological cross-sectional area of ACE-083-injected TA muscle was increased by 42% in mdx mice and by 70% in wild-type mice compared to vehicle-injected TA muscle in these respective mouse strains (Fig. 5c).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11490153
Then, 10.000 cells/well were added to the 96-well plates and incubated for 24 to reach 80%.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Then", ",", "10.000", "cells/well", "w...
PMC11424574
Our study findings are consistent with these other studies, suggesting that MTA2 depletion decreased the metastatic capacity of osteosarcoma cells by inhibiting uPA expression.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11626627
TWIST1 (Twist family basic helix-loop-helix transcription factor 1) is a protein-coding gene, which is also an important transcription factor(TF), playing a crucial role in embryonic development .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11621493
BAT, brown adipose tissue; CM, cardiac muscle; iWAT, inguinal white adipose tissue; gWAT, gonadal white adipose tissue; SM, skeletal muscle; SI, small intestine; PLA2G4, phospholipase A2 group IV.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11790971
For each cross-validation fold, balanced accuracies were calculated on test set cells from monoclonal wells, while impurity scores were calculated on test set cells from all wells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7887261
Additionally, our assays of cellular DNA damage identified POMC and MLNR as part of the DNA damageome, and confirmed a double-strand break repair role of ATM.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7709199
The side chain of Gln240 points towards the D3 packing interface, leaving no space to accommodate an N-linked glycan.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "side", "chain", ...
PMC3203927
It measures the similarity between two profiles by calculating the linear relationship of the distributions of the two corresponding random variables.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "measures", ...
PMC11087766
Clustal Omega generated protein sequence alignment of PhiPA3 gp108 and PhiKZ gp104. “*”
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Clustal", "Omega", "generated", "protein", "sequence", "alignment...
PMC11451940
Iron can participate in several biological processes, such as respiration, photosynthesis, N2 fixation and H2 metabolism.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Iron", "can", "participate", "in"...
PMC11321678
Peak track of specific co‐accessibility and target genes in each cluster.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Peak", "track", "of", "specific", "co‐accessibility", "and", "target", "genes", "in", ...
PMC2614416
Annotation: The annotation procedure selects the GO terms from the GO pool obtained by the Mapping step and assigning them to the query sequences, using Annotation Rule.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9119314
In this study, the semi-synthetic analogues 4–6 exhibited potent in vitro antitrypanosomal activities with modest selectivity compared with their cytotoxicity against Hep G2 cells (Table 2), while 3 was 3- to 6-fold less active.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "O", "...
PMC11201989
At the immune synapse, signaling molecules accumulate in specific regions like the supramolecular activating complex at the center of the synapse, to facilitate efficient T-cell signaling .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11594588
These platelet receptors, glycoprotein, and thrombin are required for platelet aggregation and activation at sites of vascular injury .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "platelet", "recepto...
PMC11155445
In one complex intramolecular π stacking sandwich interaction between two phenyl groups was observed while the other lacked this type of interaction.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "one", ...
PMC10831439
First, CD19-CAR-iNKT cells and untransduced iNKT cells were tested against mo-DCs that were used as HLA mismatched stimulators of T cells in subsequent assays.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10587429
However, for an aggressive cancer such as ES, this is not an issue.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "for", "an", "aggressive", "cancer", "such",...
PMC11724582
YAP/TAZ are the principal molecules of the Hippo pathway and have been demonstrated to be related to CAFs and various physiological functions in tumors .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC10919056
ROC curve analysis of the RS prognostic model in the training set. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ROC", "curve", "analysis", "of", "the", "RS", "prognostic", "model", ...
PMC11711063
Representative F‐FDG PET/CT image of SCID mice xenografted with MDA‐MB‐231 cells, treated by vehicle or Bex + Carv for 8 weeks. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11746948
k, l Immunoblots of GPX4 in A375 cells infected with Flag-GPX4-WT or Flag-GPX4-C75S, followed by CHX treatment for indicated times (k).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ],...
PMC11321678
These findings underscore the subgroup‐specific nature of the TF‐NTR network, suggesting the necessity for tailored therapeutic strategies for different medulloblastoma subtypes.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "fin...
PMC10758402
p < 0.01 and ****p < 0.0001.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "p", "<", "0.01", "and", "*", "*", "*", "*", "p", "<", "0.0001", "." ]...
PMC10006224
We postulate that cohesin-STAG1 associates with chromatin near CTCF sites or arrives there and becomes arrested even when NIPBL levels are very low (Fig. 6).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11412721
Design and construction of the Trp53 mouse model were previously described (Simeonova et al., 2013).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Design", "and", "construction", "of", ...
PMC9429973
To improve uptake and tissue retention, we chose a modified short peptide ligand harbouring an LDV motif with high affinity towards the very late antigen-4 (VLA-4) that is widely expressed across haematopoietic cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9966931
The cytotoxic effect of the six hybrid molecules was assessed by means of the brine shrimp lethality assay (BSLA) described by Meyer et al. .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC7090062
Gastrointestinal stromal tumors (GISTs) are the most common gastrointestinal mesenchymal tumors in the alimentary tract, accounting for 0.2% of all gastrointestinal tumors.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC8916024
Previously, we found that the utilization of protein and carbohydrates by juvenile snails was higher than that of adult snails (Zhou et al., 2021).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11655498
Zta and Rta can also activate their promoters (Israel and Kenney, 2003), further boosting the expression of subsequent EBV early and late genes through positive feedback.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11583010
During the study, the care and use of animals was conducted in accordance with the regulations of the Association for Assessment and Accreditation of Laboratory Animal Care.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10705095
These findings suggest that HBQ1 functions as an antioxidant, modulating ROS levels and protecting lung adenocarcinoma cells from proliferation inhibition.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "findings", ...
PMC11525293
Thal was added 17 h post cell seeding; after 24 h of treatments, 50 μL of pseudo-SARS-CoV-2 suspension (viral titer: 2 × 10 viral genes (VG) per mL) was added to each well following the manufacturer’s instructions.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9688728
Further work in this area will validate the hypothesis in follow-up experiments with orthogonal approaches (e.g., LC-MS vs. GC-MS) and quantify changes for normalizing data obtained at different passages.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9100622
Our observation that the statin effect can be rescued by end products of the MVA pathway clearly points out that the inhibition of this pathway is the key effect of statin.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7762347
Mainly it targets the liver, due to its active transport via hepatic organic anion transport polypeptides (OATP) .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Mainly", "it", "targets", ...
PMC11627060
Cells were rinsed with phosphate-buffered saline (PBS) and analyzed using a 40× fluorescent microscope.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", "were", "rinsed", "with", "phosphate-buff...
PMC8735881
Definitely, the current generation bNAbs also offer promising candidates for developing therapeutic drugs and HIV-resistant cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Definitely", ",", "the", "current", "generation",...
PMC11774251
Specifically, Tan-I might enhance the terminal differentiation process of keratinocytes, thereby reducing inflammatory responses and keratinocyte hyperproliferation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Specifically", ",", "Tan-I", "mig...
PMC11470381
θ = angle perpendicular to the major axis, φ = angle (radians) subtended by the minor axis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "θ", "=", "angle", "per...
PMC11477621
ICR mice (n = 6) were fasted for 12 h before administration and remained fasting for 2 h. The animal room environment was controlled (target conditions: temperature 18 to 29 °C, relative humidity 30 to 70%).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11803149
Anti-Epas1 antibody (NOVUS Bio, NB100-122SS) was incubated on membranes at 4°C overnight, followed by HRP-tagged secondary antibody incubation at room temperature for 2 h. Chemiluminescent signals were developed with Clarity ECL substrate (Bio-Rad, 170-5060) and detected using an iBright™ CL1500 Imaging System (Thermo).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6450504
It is worth noting that, on day 18, two out of four animals in the 0.5% PEIPOS/PTX/siMDR1 group had tumor volumes below 500 mm, which did not occur in any animal of the other groups in this study, which showed volumes above 1000 mm.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Sixteen (84%) patients had progression of disease within 24 months of initial therapy.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Sixteen", "(", "84", "%", ")", "patients", "had"...
PMC10674574
Additionally, the moderate-permeability group includes drug models with Papp values from 1.29 to 16.0 [×10 cm/s].
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "the", "moder...
PMC11306019
MM is a hematological malignancy characterized by the uncontrolled clonal proliferation of plasma cells derived from B cells within the bone marrow cavity.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "MM", ...
PMC11394730
Curcumin has been proven to be an effective treatment for several types of cancer, as shown in Figure 3.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Curcumin", "has", "been", ...
PMC9444294
Cells were incubated with goat anti-rabbit secondary antibody (dilution 1:800; Invitrogen, #A11012, Waltham, MA, USA) for 1 hour and mounted with Vectashield containing 4',6-diamidino-2-phenylindole (DAPI).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11672142
Def and Trp, in contrast, are orally bioavailable.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Def", "and", "Trp", ",", "in", "contrast", ",", "are", "orally", "bioavailable", "." ]...
PMC11687167
It was shown to be a member of the proprotein convertase (PC) family, which cleaves a variety of substrates, such as growth factors, transcription factors, enzymes, hormones, and receptors.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11560255
Based on this problem, looking for anti cancer agents based on natural ingredients with low side effects and a better ability to kill cells is necessary.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8735881
The results of three independent experiments are shown with different colours of lines.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "results", "of", "three", "independent", "experiments", "are", "shown...
PMC8633974
PCR final contents were run in 1.5% (w/v) agarose/TAE gels by electrophoresis at 75V for 35 minutes.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "PCR", "final", "contents", ...
PMC11742047
Except for triglycerides and diglycerides, where CBD-treated cells exhibit higher levels, the heatmaps and the network representation of the total lipid set reveal a reduction in lipid levels in CBD-treated cells (Fig. 5).Fig.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11513011
In 5637, DIB decreased the expression of N-cadherin and Vimentin.
[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "5637", ",", "DIB", "decreased", "the", "expression", "of", "N-cadherin", ...
PMC11678368
Moreover, good agreement between the simulated and experimental spectra indicates that the calculated molecular geometry is correct.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "good", "agreement", "...
PMC11700247
Working model: time line and schematic representation of in vivo A20 tumor–bearing mice treated with 2 × 4-Gy or 1 × 8-Gy RT in 1 of the 2 tumors. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Patients with multiple adverse factors appear to do better than with R-CHOP, while those with 0-1 factor have similar outcomes to R-CHOP but with minimal consolidative RT.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11591030
NO.
[ { "tags": [ "O", "O" ], "tokens": [ "NO", "." ] } ]
PMC10329237
The consequences are inducing cellular migration and accumulation of the extracellular matrix (ECM) in the lung tissue (5).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "conse...
PMC9429973
The group with normal MAGE-C1 gene expression (0.003 to 0.05, 2ΔCt) consisted of 25 patients and the group with increased expression (0.07 to 14.12, 2ΔCt) consisted of 56 patients.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7759933
Phosphate-buffered saline (PBS), methanol, and ethanol were purchased from PAA Laboratories (Dartmouth, NH, USA).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Phosphate-buffered...