OTAR3088/BioData-CellLine_annotated · Datasets at Hugging Face

PMCID string	Sentences string	ner list
PMC11411131	DEM was purchased from Tokyo Chemical Industry (Chuo-Ku, Tokyo, Japan).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "DEM", "was", "purchased", "from", "Tokyo", "Chemical", "Industry", ...
PMC7215722	Cytokines play an important role in the maintenance of barrier function and have been suggested to be responsible for the disruption of the monolayer.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11474209	Abbreviations: ATP: Adenosine triphosphate; Bax: Bcl-2-associated X protein; Bcl-2: B-cell leukemia/lymphoma 2 protein; Bid: BH3 Interacting-domain death agonist; cGAS: Cyclic GMP-AMP synthase; Cyt C: Cytochrome complex; DNA: Deoxyribonucleic acid; DNA-PK: DNA-dependent protein kinase; ETC: Electron transport chain; HRR: Homologous recombination repair; IFN β: Interferon beta-1; IFS: Intermediate filaments; IRF3: Interferon regulatory factor 3; MCLR: Microcystin-Leucine arginine; MC-LR: Microcystin-Leucine Arginine; MFS: Microfilaments; MMP: Mitochondrial membrane potential; MPT: Membrane-permeabilization transition; MTs: Microtubules; NAD+: Nicotinamide adenine dinucleotide; NADH: Nicotinamide adenine dinucleotide; NF-kβ: Nuclear factor kappa-light-chain-enhancer of activated B cells; OATP: Organic anion transporter peptides; OATP: Organic anion transporter peptides; OS: Oxidative stress; PARP1: Poly (ADP-ribose) polymerase 1; PP1: Protein phosphatase-1; PP2A: Protein phosphatase 2A; ROS: Reactive oxygen species; STING: Stimulator of interferon genes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11489351	For non-normally distributed data, statistical significance was determined using Kruskal–Wallis test with Dunn’s multiple-comparisons correction to compare mean ranks.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", ...
PMC6222726	Their flowers can be solitary but often develop in conglomerates at the end of branches of reddish-yellow color.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Their", "flowers", "can", "be", "solit...
PMC11746948	b Co-immunoprecipitation in 293T cells transiently transfected with Flag-GPX4 and HA-APT2 plasmids to investigate GPX4-APT2 interaction detected by immunoblots.	[ { "tags": [ "O", "O", "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "b", "Co-immunopr...
PMC10898159	It regulates mesenchymal progenitor proliferation and differentiation by controlling the Hippo effector Yes-associated protein 1 (YAP1), which is constitutively activated in many sarcomas .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9622879	In particular, the LEM enables energy sharing among prosumers, thereby offering a powerful and complete exploitation of the prosumer DERs within the community and reducing the grid dependence of the community.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11789597	The therapeutic efficiency of MoAbs largely relies on the expression of their targets on the MM cell surface and the activation of effector immune cells, especially NK cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11464609	c Consistent with the increased proportion of viral reads, viral genome coverages are significantly higher in samples #1 to #14 when using the viral capture panel compared to conventional metagenomics (p = 0.044, paired t test).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9046263	We utilized only paired-end ribosomal depleted samples from ENCODE with RNA fragments > 200 bp in our analyses.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "utilized", "only", "paired-end", ...
PMC11675244	Given that Wnt is a key regulator of EMT and VEGF is a target of the β-catenin/TCF complex , it is reasonable to propose that Wnt signaling is critical in promoting cancer invasion and spreading.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11635519	The GROMACS software package version 2019.3 was used to perform the molecular dynamics (MD) simulations of the GLP-1R+peptide complexes using the CHARMM36-m force field and TIP3P water model.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Polychemotherapy strongly reduced PDX ALL cells within the first weeks, proving initial sensitivity of the sample.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Polychemotherapy", "strongly", "reduced", "PDX", ...
PMC9503669	The Nef-BiFC to mRFP ratios from cells expressing wild-type Nef versus a dimerization-defective Nef mutant were very clearly separated, with Z’ factors in the 0.6 to 0.7 range.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8735881	Currently, there are tremendous works to engineer CCR5 mutations into autologous cells using gene-editing technologies; however, the allogeneic transplantation of CCR5 gene-edited HSCs has so far achieved only very limited therapeutic efficacy in patients [5–7].	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11224020	Of note, CCR7 expressed at the surface of DCs confined at a height of 3 µm was fully functional; only these cells exhibited chemotaxis when CCL19 was added at one side of the confinement device (Fig. 1h,i).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC2777936	Active-β-catenin levels in NT2/D1 cells following RA treatment.	[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O" ], "tokens": [ "Active-β-catenin", "levels", "in", "NT2/D1", "cells", "following", "RA", "treatment", "." ] } ]
PMC8806312	CSF3R expression is positively related to prognosis in patients with acute myeloid leukemia .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CSF3R", "expression", "is", "positively", "related", "to", "prognosis", "in...
PMC11802929	Bar level represented the mean variable value.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Bar", "level", "represented", "the", "mean", "variable", "value", "." ] } ]
PMC9429973	Mean plasma amino acid levels (µmol/L) at baseline were: asparagine (Asn) 29 (17-38), glutamine (Gln) 421 (384-465), glutamate (Glu) 59 (22-103), serine (Ser) 66 (49-80) and glycine (Gly) 203 (166-207).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9096373	The tumor metabolism and volume in the APA + RT group were obviously reduced compared with the control, RT, and DDPs + RT groups.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11476004	There is little information on the use of the comet assay in dogs .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "There", "is", "little", "information", "on", "the", "use", "of", "the...
PMC11525028	Asn level in NAT10-KO 143B (top) and HOS (bottom) cells by UHPLC-MS/MS targeted amino acids (n = 3). (	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC11489351	Labeled are a subset of identified transcripts that are differentially regulated at high and low pHi (magenta upregulated, cyan downregulated).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Labeled...
PMC11543885	Remove the final wash and incubate the cells with 100 μL AF488-conjugated goat anti-rabbit IgG (H + L) secondary antibody in 1% (wt/vol) BSA for 1 h at 25°C (1: 1000 dilution).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11574029	C, D Western blot analysis of changes in PI3K/AKT pathway-related proteins and their phosphorylation levels after knocking down SPP1 in T24 and 5637 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "...
PMC11637276	We observed that α2 integrin expression increased in breast and pancreatic tumours and correlated with poor survival.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "observed", "that", "α2", "integrin", ...
PMC7642379	The need for new safe and efficacious therapies has led to an increased focus on biologics produced in mammalian cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "need", "for", "...
PMC11549612	Therefore, there is a pressing need to explore and validate novel biomarkers that can fill this crucial gap in KIRC research and clinical practice.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC7823217	Fig. B is reproduced from Ref.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fig.", "B", "is", "reproduced", "from", "Ref", "." ] } ]
PMC10975211	These bioconjugates offer controlled release and targeted delivery, minimizing off-target effects and potentially overcoming drug resistance in cancer cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "bioconjugates", "of...
PMC9429973	ATG was used for haploidentical or unrelated transplants.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ATG", "was", "used", "for", "haploidentical", "or", "unrelated", "transplants", "." ] } ]
PMC5535901	Moreover, I3C and DIM pretreatment, in a dose-dependent manner, further enhanced the inflammatory cytokine expression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "I3C", "and", "DIM", ...
PMC11682525	One-day hypoxic preconditioning in SH-SY5Y cells and three-day hypoxic preconditioning in hHFSCs resulted in significant downregulation of HIF1α mRNA (P<0.01; Fig. 6), with a concurrent approximately 600% increase in VEGF transcripts (P<0.001; Fig. 6).	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC10919056	Alterations in the TME and the infiltration of immune cells have garnered significant attention in the field of cancer therapy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Alterations", "in", "the", ...
PMC9872547	The expression of P53 and Rb genes was not significantly altered in nano-curcumin-treated fibroblasts (Figure 3C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "expression", "of", "P53", "and"...
PMC9429973	However, the datasets in this field concern a limited number of individuals.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "the", "datasets", "in", "this", "field", "concern", "...
PMC11194678	Such aggregates generally could only be recognized by macroautophagy for degradation but not the ubiquitin-proteasome system or chaperone-mediated autophagy; thus macroautophagy has been regarded as an effective neuroprotective mechanism to clear these pathogenic and toxic proteins such as α-synuclein, TDP-43, tau, and huntingtin (Ciechanover and Kwon, 2015; Fleming et al., 2022; Zhao et al., 2021).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11634794	The 786-O cell line was cultured in Roswell Park Memorial Institute 1640 medium containing 10% fetal bovine serum.	[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "786-O", "cell", "...
PMC10976516	OV-infected tumor cells undergoing oncolysis produce HSPs, which trigger the generation of chemokines and activate dendritic cells (DCs) via the TLR4 pathway.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9599726	Flow cytometry analysis of C11-BODIPY green fluorescence was used as a readout for membrane lipid peroxidation, a hallmark of ferroptosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Flow", "cytometry", ...
PMC11469524	Left panel denotes which site was found to be significantly regulated (blue—down; red–up) by the indicated comparison.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC10656496	Spheroids were treated with chemotherapy for 96 h, washed and treated with CA1 for 72 h, and then the process was repeated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11286266	Schematic representation of engineered stable 2K cells with the endogenous cgATF6α locus (in orange) tagged with 3xFLAG (in red) and mGreenLantern (mGL) (in green) at the N-terminus. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11617590	As the suppression of NF‐κB results in a decrease in B‐cell lymphoma 2 (BCL‐2) which is the anti‐apoptotic gene, we tested the effect of SFN in the expression of BCL‐2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11745823	A two‐sided p‐value of 0.05 indicated statistical significance.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "two‐sided", "p‐value", "of", "0.05", "indicated", "statistical", "significance", "." ] } ]
PMC9429973	Of 24 pts with BL T-scores ≥–1.0, 21 pts remained stable, and 3 pts had worsening BMD.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Of", "24", "pts", "with", "...
PMC11588008	In real-time fluorescence quantitative PCR analysis, the expression of HO-1 and Nrf-2 genes decreased after exposure to PM (P < 0.05).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC8389560	Besides, after incubation of cell cultures with 2.5 and 5 µg/mL SeNPs for 30 min using the Apoptosis/Necrosis Detection Kit assay, no cells with apoptosis and necrosis were detected (Supplementary, Figure S1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11655498	EBV G-protein-coupled receptor BILF1 recruits the E3 ligase UFL1 (UFM1 specific ligase 1) to facilitate the interaction between MAVS and UFM1 (ubiquitin fold modifier 1), leading to the MAVS UFMylation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Pts will be followed for up to 15 years after infusion in a separate protocol.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Pts", "will", "be", "followed", "for", "up", "to", "1...
PMC9429973	Molecular variants were detected in 10/15 pts (66%), 8/10 were novel.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Molecular", "variants", "were", "detected", "in", "10/15", ...
PMC11476837	In the case of experimental scheme 3, HL-60/DR cells were seeded in 25 cm flasks at a density of 5 × 10 cells/mL. Then, the cells were incubated with NRF2 inhibitors at concentrations of 5 and 50 μM for 24 h. After this time, cells were washed two times with warm PBS and seeded onto 6-well plates in the count of 200,000 cells per well in medium.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11098378	Thus, we took advantage of a prior study that developed guidelines for designing siRNAs to achieve efficient knockdown in another moth species, Bombyx mori, as a basis for our siRNA design for use in LD652 cells .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11467800	This landscape is a dynamic structure and offers acquired transcriptional flexibility as a stress response, allowing for a unique resistance model.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "land...
PMC11742670	CNN can autonomously acquire layered data representations, which are more durable and descriptive compared to manually crafted features.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CNN", "can", "autonomously", "acq...
PMC11420784	Taken together, we found that PldA-dependent inhibition of preautophagosomal structure maturation results in the formation of NDP52 granules in the cytosol of infected cells, contributing to protection of UPEC against autophagic targeting.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11673902	This measurement helps to distinguish between these two different types of cells, thus providing valuable data for cell mechanics studies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "measurement", ...
PMC11434983	In addition, the IC50 value for the anticancer scaffold 6-amino-4-[3-bromophenyl]quinazoline is 4.8 ± 0.2 μΜ, showing that both complexes have an enhanced cytotoxic activity compared to the scaffold, which might be attributed to the metal component .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11201245	Tan et al. (2011) confirm comparable gains and losses in clear cell ovarian carcinomas even in all three loci .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Tan", "et", "al."...
PMC8097906	The two treatments induced a similarly altered metabolite profile in the RH-30 cells compared to the untreated control cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "two", "treatments", ...
PMC6222635	Searching the HMBC spectrum, we found the signal (100.04, 3.72); the signal 100.04 is the same as the 100.10 signal of the anomer carbon of (1→4)-linked mannose.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	PCT involvement was considered of added value by healthcare professionals in 4.9% of all admitted patients at hematology wards.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "PCT", "involvement", "was", ...
PMC11787651	Metaboanalyst (https://www.metaboanalyst.ca/docs/About.xhtml) was used to visualize data.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Metaboanalyst", "(", "https://www.metaboanalyst.ca/docs/About.xhtml", ")", "was", "used", "to", "visualize", "dat...
PMC11283030	Kaplan-Meier survival curve demonstrated that high ACLY and p-ACLY expression were negatively correlated with CSS rate of the 145 ccRCC patients (P = 0.004, P = 0.003, respectively, Fig. 2c).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11687663	Schaftoside (B7), part of phytoconstituent of plant A. helferiana, has demonstrated promising drug potential despite violating Lipinski’s Rule of 5.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11666785	The other aspect of corrSMLM is the degree of correlation with which two spots can be recognized as a single-molecule (referred as pair-molecule/fortunate molecule).Specifically, three different values of correlation factor, (χ) of ≥0.7, ≥0.8 and ≥0.9 are chosen and corresponding images are reconstructed as shown in Fig. 3A.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11657744	siRNA-mediated knockdown in cultured cells revealed gene-specific regulatory effects on ciliary assembly and disassembly.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "siRNA-mediated", "knockdown", "in", "cultured", "cells", "revealed", "...
PMC11472569	The ABCE and ABCF families do not function as transporters but act as regulators of mRNA translation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "ABCE", "and", "ABCF", "families", "d...
PMC11528603	The plates were shaken at 700 rpm for 10 minutes and measured absorbances at the wavelength 550 nm (OD550nm) by Multiskan plate reader (Thermo, the USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11637276	For wound healing experiments, SW1990 cells were detached using Trypsin-EDTA and neutralised using 10% FBS DMEM.	[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "wound", "healing", "experime...
PMC11665555	The differences in wound closure were normalized and compared with the control using 1-way ANOVA at a 95 % CI.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "differences", "in", ...
PMC11286266	These findings indicated that CRT represses both ER-to-Golgi trafficking and processing of ATF6α into its active form.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "findings", "indicated", "that", "CRT", ...
PMC9429973	The statistical analysis was performed using statistical package for social sciences (SPSS), version 25.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "statistical", "analysis", "was", "performe...
PMC11626627	Fig 2 Differential expression of TWIST1 in various cancers and its prognostic value in KIRC. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fig", "2", "Differential", "expression", "of", "TWIST1...
PMC11791432	The data were then normalized using the LogNormalize method, and the vst method was used to select 2000 hypervariable genes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "data", "we...
PMC9341513	See also Supplemental Table S4.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "See", "also", "Supplemental", "Table", "S4", "." ] } ]
PMC4485786	Slides were then incubated with rabbit anti-p-HP1γ (1:80; Abcam, UK), mouse-anti-PCNA (1:50; Cell Signaling Technology, MA), mouse anti-p16 (1:50; Santa Cruz Biotechnology, Germany), or rabbit anti-Ki67 (1:100; Abcam, USA) for 1 h at RT.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7582629	The symmetric stretching terminal −CH3 group from the nuclei is markedly blue-shifted for the cancer cells (at 2936 and 2939 cm for the MCF7 and MDA-MB-231 cells, respectively) when compared to control (at 2933 cm).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", ...
PMC11013014	H NMR (400 MHz, CDCl3), δ (ppm): 8.91 (s, 1H), 8.16 (d, JHH = 1.9 Hz, 1H), 8.00 (dd, JHH = 1.9, 8.1 Hz, 1H), 7.88 (d, JHH = 8.1 Hz, 1H), 7.26 (d, JHH = 8.5 Hz, 1H), 6.96 (d, JHH = 8.5 Hz, 1H), 6.00 (s, 1H), 5.62 (s, 1H), 4.77 (s, 2H), 3.21 (s, 3H), 2.51 (q, JHH = 7.4 Hz, 2H), 1.18 (t, JHH = 7.4 Hz, 3H).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11583010	To confirm the hits and assess specificity, vectors encoding all hits identified in the first library screen, plus vectors encoding CD20 and EGFR, were arrayed and expressed in HEK293 cells on new slides.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11534035	Protein isolation was performed 72 h after treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Protein", "isolation", "was", "performed", "72", "h", "after", "treatment", "." ] } ]
PMC9429973	According to the protocol for the treatment of ALL, full doses of GCs (100%) and anthracyclines (ATC) (100%) were used, lumbar punctures (LP) and intrathecal (IT) injections of CT (100%) were continued.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11531744	Additionally, the 243 IRGs expression heat-map of all OC patients in the training cohort were shown in Fig. 2C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "the", ...
PMC11023271	Briefly, 20,000 HaCaT cells expressing control or shRIPK4 were plated in each of six wells of a 96-well plate overnight.	[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Briefly", ",",...
PMC11730311	Data point represent mean and range of n = 2, except for C20DA-γGlu protraction at position 17 where n = 1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "poin...
PMC10812665	The reduced fMet levels may make mitochondrial protein synthesis impossible, and this would contribute to a perturbed homeostasis of mitochondrial proteins upon prolonged toxicant exposure.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11599565	This neurofilament is mainly localized in the axonal regions of neurons where it helps to stabilize the axons and facilitates axonal transport.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "neur...
PMC9429973	Patients 6 and 10 had the initial semen analysis after 736 and 475 days, respectively, from commencing TKI therapy and all remaining patients had it before starting.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	We investigated alemtuzumab, a humanized IgG1 monoclonal antibody targeting CD52.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "investigated", "alemtuzumab", ",", "a", "humanized", "IgG1", "monoclonal", "antibody"...
PMC11746948	Collectively, these results indicate that ZDHHC20 plays a crucial role in the palmitoylation of GPX4, significantly influencing the ferroptosis sensitivity of cancer cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11320084	After transfection of si‐TNNT1 and treatment with 20 mmol/L LiCl for 24 h, it was found that LiCl could partially restore cell migration, invasion and EMT after TNNT1 knockdown (Figures 4 and 5).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10728200	Combination index (CI) values were calculated based on the drug combination principles, as proposed by Chou—Talalay (CI <1, =1, and >1 indicate synergic, additive or antagonistic effects, respectively) .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11767793	A full cell growth inhibition was recorded at CAuPEI@NIST = 12 μg/mL, while the cell viability remained above 80% for CAuPEGCOOH@NIST = 50 μg/mL for all the tested cell lines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5833712	The highest rates are reported in Scandinavia, Eastern Europe, USA, and Canada.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "highest", "rates", "are", "reported", "in", "Scandin...
PMC11285179	Chemotactic factors influence cellular metabolism by regulating intracellular signaling pathways, such as PI3K/AKT, MAPK, AMPK, and mTOR .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Chemotactic", "factors"...
PMC8633974	Notably, tat-directed gRNAs retain full 20 bp complementarity for 6-67% of all known HIV-1 strains (Table S3).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Notably...
PMC8973085	H NMR spectra were run at 400 MHz and C NMR spectra were run at 100 MHz in deuterated chloroform (CDCl3) or dimethyl sulfoxide (DMSO-d6) as specified in individual compound characterizations.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11653533	Furthermore, F. microcarpa dry leaves, ethereal roots, and bark were utilized in folk pharmaceuticals for decreasing fever, soothing pain, and the treatment of liver disorders (Rjeibi et al., 2017).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11411131

DEM was purchased from Tokyo Chemical Industry (Chuo-Ku, Tokyo, Japan).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "DEM", "was", "purchased", "from", "Tokyo", "Chemical", "Industry", ...

PMC7215722

Cytokines play an important role in the maintenance of barrier function and have been suggested to be responsible for the disruption of the monolayer.

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PMC11474209

Abbreviations: ATP: Adenosine triphosphate; Bax: Bcl-2-associated X protein; Bcl-2: B-cell leukemia/lymphoma 2 protein; Bid: BH3 Interacting-domain death agonist; cGAS: Cyclic GMP-AMP synthase; Cyt C: Cytochrome complex; DNA: Deoxyribonucleic acid; DNA-PK: DNA-dependent protein kinase; ETC: Electron transport chain; HRR: Homologous recombination repair; IFN β: Interferon beta-1; IFS: Intermediate filaments; IRF3: Interferon regulatory factor 3; MCLR: Microcystin-Leucine arginine; MC-LR: Microcystin-Leucine Arginine; MFS: Microfilaments; MMP: Mitochondrial membrane potential; MPT: Membrane-permeabilization transition; MTs: Microtubules; NAD+: Nicotinamide adenine dinucleotide; NADH: Nicotinamide adenine dinucleotide; NF-kβ: Nuclear factor kappa-light-chain-enhancer of activated B cells; OATP: Organic anion transporter peptides; OATP: Organic anion transporter peptides; OS: Oxidative stress; PARP1: Poly (ADP-ribose) polymerase 1; PP1: Protein phosphatase-1; PP2A: Protein phosphatase 2A; ROS: Reactive oxygen species; STING: Stimulator of interferon genes.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11489351

For non-normally distributed data, statistical significance was determined using Kruskal–Wallis test with Dunn’s multiple-comparisons correction to compare mean ranks.

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PMC6222726

Their flowers can be solitary but often develop in conglomerates at the end of branches of reddish-yellow color.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Their", "flowers", "can", "be", "solit...

PMC11746948

b Co-immunoprecipitation in 293T cells transiently transfected with Flag-GPX4 and HA-APT2 plasmids to investigate GPX4-APT2 interaction detected by immunoblots.

[ { "tags": [ "O", "O", "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "b", "Co-immunopr...

PMC10898159

It regulates mesenchymal progenitor proliferation and differentiation by controlling the Hippo effector Yes-associated protein 1 (YAP1), which is constitutively activated in many sarcomas .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...

PMC9622879

In particular, the LEM enables energy sharing among prosumers, thereby offering a powerful and complete exploitation of the prosumer DERs within the community and reducing the grid dependence of the community.

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PMC11789597

The therapeutic efficiency of MoAbs largely relies on the expression of their targets on the MM cell surface and the activation of effector immune cells, especially NK cells.

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PMC11464609

c Consistent with the increased proportion of viral reads, viral genome coverages are significantly higher in samples #1 to #14 when using the viral capture panel compared to conventional metagenomics (p = 0.044, paired t test).

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PMC9046263

We utilized only paired-end ribosomal depleted samples from ENCODE with RNA fragments > 200 bp in our analyses.

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PMC11675244

Given that Wnt is a key regulator of EMT and VEGF is a target of the β-catenin/TCF complex , it is reasonable to propose that Wnt signaling is critical in promoting cancer invasion and spreading.

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PMC11635519

The GROMACS software package version 2019.3 was used to perform the molecular dynamics (MD) simulations of the GLP-1R+peptide complexes using the CHARMM36-m force field and TIP3P water model.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Polychemotherapy strongly reduced PDX ALL cells within the first weeks, proving initial sensitivity of the sample.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Polychemotherapy", "strongly", "reduced", "PDX", ...

PMC9503669

The Nef-BiFC to mRFP ratios from cells expressing wild-type Nef versus a dimerization-defective Nef mutant were very clearly separated, with Z’ factors in the 0.6 to 0.7 range.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8735881

Currently, there are tremendous works to engineer CCR5 mutations into autologous cells using gene-editing technologies; however, the allogeneic transplantation of CCR5 gene-edited HSCs has so far achieved only very limited therapeutic efficacy in patients [5–7].

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11224020

Of note, CCR7 expressed at the surface of DCs confined at a height of 3 µm was fully functional; only these cells exhibited chemotaxis when CCL19 was added at one side of the confinement device (Fig. 1h,i).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC2777936

Active-β-catenin levels in NT2/D1 cells following RA treatment.

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PMC8806312

CSF3R expression is positively related to prognosis in patients with acute myeloid leukemia .

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PMC11802929

Bar level represented the mean variable value.

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PMC9429973

Mean plasma amino acid levels (µmol/L) at baseline were: asparagine (Asn) 29 (17-38), glutamine (Gln) 421 (384-465), glutamate (Glu) 59 (22-103), serine (Ser) 66 (49-80) and glycine (Gly) 203 (166-207).

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PMC9096373

The tumor metabolism and volume in the APA + RT group were obviously reduced compared with the control, RT, and DDPs + RT groups.

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PMC11476004

There is little information on the use of the comet assay in dogs .

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PMC11525028

Asn level in NAT10-KO 143B (top) and HOS (bottom) cells by UHPLC-MS/MS targeted amino acids (n = 3). (

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PMC11489351

Labeled are a subset of identified transcripts that are differentially regulated at high and low pHi (magenta upregulated, cyan downregulated).

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PMC11543885

Remove the final wash and incubate the cells with 100 μL AF488-conjugated goat anti-rabbit IgG (H + L) secondary antibody in 1% (wt/vol) BSA for 1 h at 25°C (1: 1000 dilution).

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PMC11574029

C, D Western blot analysis of changes in PI3K/AKT pathway-related proteins and their phosphorylation levels after knocking down SPP1 in T24 and 5637 cells.

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PMC11637276

We observed that α2 integrin expression increased in breast and pancreatic tumours and correlated with poor survival.

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PMC7642379

The need for new safe and efficacious therapies has led to an increased focus on biologics produced in mammalian cells.

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PMC11549612

Therefore, there is a pressing need to explore and validate novel biomarkers that can fill this crucial gap in KIRC research and clinical practice.

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PMC7823217

Fig. B is reproduced from Ref.

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PMC10975211

These bioconjugates offer controlled release and targeted delivery, minimizing off-target effects and potentially overcoming drug resistance in cancer cells.

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PMC9429973

ATG was used for haploidentical or unrelated transplants.

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PMC5535901

Moreover, I3C and DIM pretreatment, in a dose-dependent manner, further enhanced the inflammatory cytokine expression.

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PMC11682525

One-day hypoxic preconditioning in SH-SY5Y cells and three-day hypoxic preconditioning in hHFSCs resulted in significant downregulation of HIF1α mRNA (P<0.01; Fig. 6), with a concurrent approximately 600% increase in VEGF transcripts (P<0.001; Fig. 6).

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PMC10919056

Alterations in the TME and the infiltration of immune cells have garnered significant attention in the field of cancer therapy.

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PMC9872547

The expression of P53 and Rb genes was not significantly altered in nano-curcumin-treated fibroblasts (Figure 3C).

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PMC9429973

However, the datasets in this field concern a limited number of individuals.

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PMC11194678

Such aggregates generally could only be recognized by macroautophagy for degradation but not the ubiquitin-proteasome system or chaperone-mediated autophagy; thus macroautophagy has been regarded as an effective neuroprotective mechanism to clear these pathogenic and toxic proteins such as α-synuclein, TDP-43, tau, and huntingtin (Ciechanover and Kwon, 2015; Fleming et al., 2022; Zhao et al., 2021).

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PMC11634794

The 786-O cell line was cultured in Roswell Park Memorial Institute 1640 medium containing 10% fetal bovine serum.

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PMC10976516

OV-infected tumor cells undergoing oncolysis produce HSPs, which trigger the generation of chemokines and activate dendritic cells (DCs) via the TLR4 pathway.

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PMC9599726

Flow cytometry analysis of C11-BODIPY green fluorescence was used as a readout for membrane lipid peroxidation, a hallmark of ferroptosis.

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PMC11469524

Left panel denotes which site was found to be significantly regulated (blue—down; red–up) by the indicated comparison.

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PMC10656496

Spheroids were treated with chemotherapy for 96 h, washed and treated with CA1 for 72 h, and then the process was repeated.

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PMC11286266

Schematic representation of engineered stable 2K cells with the endogenous cgATF6α locus (in orange) tagged with 3xFLAG (in red) and mGreenLantern (mGL) (in green) at the N-terminus. (

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PMC11617590

As the suppression of NF‐κB results in a decrease in B‐cell lymphoma 2 (BCL‐2) which is the anti‐apoptotic gene, we tested the effect of SFN in the expression of BCL‐2.

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PMC11745823

A two‐sided p‐value of 0.05 indicated statistical significance.

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PMC9429973

Of 24 pts with BL T-scores ≥–1.0, 21 pts remained stable, and 3 pts had worsening BMD.

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PMC11588008

In real-time fluorescence quantitative PCR analysis, the expression of HO-1 and Nrf-2 genes decreased after exposure to PM (P < 0.05).

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PMC8389560

Besides, after incubation of cell cultures with 2.5 and 5 µg/mL SeNPs for 30 min using the Apoptosis/Necrosis Detection Kit assay, no cells with apoptosis and necrosis were detected (Supplementary, Figure S1).

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PMC11655498

EBV G-protein-coupled receptor BILF1 recruits the E3 ligase UFL1 (UFM1 specific ligase 1) to facilitate the interaction between MAVS and UFM1 (ubiquitin fold modifier 1), leading to the MAVS UFMylation.

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PMC9429973

Pts will be followed for up to 15 years after infusion in a separate protocol.

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PMC9429973

Molecular variants were detected in 10/15 pts (66%), 8/10 were novel.

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PMC11476837

In the case of experimental scheme 3, HL-60/DR cells were seeded in 25 cm flasks at a density of 5 × 10 cells/mL. Then, the cells were incubated with NRF2 inhibitors at concentrations of 5 and 50 μM for 24 h. After this time, cells were washed two times with warm PBS and seeded onto 6-well plates in the count of 200,000 cells per well in medium.

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PMC11098378

Thus, we took advantage of a prior study that developed guidelines for designing siRNAs to achieve efficient knockdown in another moth species, Bombyx mori, as a basis for our siRNA design for use in LD652 cells .

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PMC11467800

This landscape is a dynamic structure and offers acquired transcriptional flexibility as a stress response, allowing for a unique resistance model.

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PMC11742670

CNN can autonomously acquire layered data representations, which are more durable and descriptive compared to manually crafted features.

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PMC11420784

Taken together, we found that PldA-dependent inhibition of preautophagosomal structure maturation results in the formation of NDP52 granules in the cytosol of infected cells, contributing to protection of UPEC against autophagic targeting.

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PMC11673902

This measurement helps to distinguish between these two different types of cells, thus providing valuable data for cell mechanics studies.

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PMC11434983

In addition, the IC50 value for the anticancer scaffold 6-amino-4-[3-bromophenyl]quinazoline is 4.8 ± 0.2 μΜ, showing that both complexes have an enhanced cytotoxic activity compared to the scaffold, which might be attributed to the metal component .

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PMC11201245

Tan et al. (2011) confirm comparable gains and losses in clear cell ovarian carcinomas even in all three loci .

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PMC8097906

The two treatments induced a similarly altered metabolite profile in the RH-30 cells compared to the untreated control cells.

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PMC6222635

Searching the HMBC spectrum, we found the signal (100.04, 3.72); the signal 100.04 is the same as the 100.10 signal of the anomer carbon of (1→4)-linked mannose.

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PMC9429973

PCT involvement was considered of added value by healthcare professionals in 4.9% of all admitted patients at hematology wards.

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PMC11787651

Metaboanalyst (https://www.metaboanalyst.ca/docs/About.xhtml) was used to visualize data.

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PMC11283030

Kaplan-Meier survival curve demonstrated that high ACLY and p-ACLY expression were negatively correlated with CSS rate of the 145 ccRCC patients (P = 0.004, P = 0.003, respectively, Fig. 2c).

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PMC11687663

Schaftoside (B7), part of phytoconstituent of plant A. helferiana, has demonstrated promising drug potential despite violating Lipinski’s Rule of 5.

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PMC11666785

The other aspect of corrSMLM is the degree of correlation with which two spots can be recognized as a single-molecule (referred as pair-molecule/fortunate molecule).Specifically, three different values of correlation factor, (χ) of ≥0.7, ≥0.8 and ≥0.9 are chosen and corresponding images are reconstructed as shown in Fig. 3A.

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PMC11657744

siRNA-mediated knockdown in cultured cells revealed gene-specific regulatory effects on ciliary assembly and disassembly.

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PMC11472569

The ABCE and ABCF families do not function as transporters but act as regulators of mRNA translation.

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PMC11528603

The plates were shaken at 700 rpm for 10 minutes and measured absorbances at the wavelength 550 nm (OD550nm) by Multiskan plate reader (Thermo, the USA).

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PMC11637276

For wound healing experiments, SW1990 cells were detached using Trypsin-EDTA and neutralised using 10% FBS DMEM.

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PMC11665555

The differences in wound closure were normalized and compared with the control using 1-way ANOVA at a 95 % CI.

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PMC11286266

These findings indicated that CRT represses both ER-to-Golgi trafficking and processing of ATF6α into its active form.

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PMC9429973

The statistical analysis was performed using statistical package for social sciences (SPSS), version 25.

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PMC11626627

Fig 2 Differential expression of TWIST1 in various cancers and its prognostic value in KIRC. (

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PMC11791432

The data were then normalized using the LogNormalize method, and the vst method was used to select 2000 hypervariable genes.

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PMC9341513