Datasets:
OTAR3088
/
BioData-CellLine_annotated

Dataset card Data Studio Files
xet
 Community
1
PMCID
string
Sentences
string
ner
list
PMC9429973
K. A. Mohamedahmed Hematology and Immunology, University of Gezira, Wad Medani, Sudan Background: Falciparum malaria is the most leading cause of mortality and morbidity in the world especially in Africa among infants and young children due to severe malaria and malaria anemia.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7192625
For human haematopoietic cells, we currently provide expression, methylation, histone modifications and expression averaged over hundred of healthy individuals, as well as replication timing for cell lines (see Table 1).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10932641
However, compared with those of the negative control group, the tumor volume and weight of mice of the siGPRC5D-AS1 group showed a significant increase (P<0.05).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11779993
SPEE was mixed with 0.1% trifluoroacetic acid (TFA), followed by filtered through a 0.45 μm membrane, and subsequently analyzed using high-performance liquid chromatography (HPLC) (Shimadzu LC-10ADvp, Kyoto, Japan) as previously described .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11127909
Next, the cells were harvested to measure the Δψm and ROS production by FACScan flow cytometry.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Next", ",", "the", "cells", "were", "harves...
PMC11587541
However, one possibility is that telomere shortening leads to genomic instability and DNA damage, which can contribute to motor neuron degeneration.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However...
PMC6901583
P < 0.05; **P < 0.01.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "P", "<", "0.05", ";", "*", "*", "P", "<", "0.01", "." ] } ]
PMC11323699
Therefore, our focus shifted to investigating the secreted and circulating form of TSP-1, quantified using plasma samples obtained pre and post chemotherapy (Fig. 4a, right panel).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11708541
The first aminopyridine to be applied in a therapeutic setting is 4-aminopyridine (4-AP) 10.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "first", "aminopyridine", "to", "be", "applied",...
PMC11536589
The limitation of this study was that we only explore the potential mechanisms of expression pattern in this study, we will further study the gene mutations in the MRTX1133-resistant PDAC cells in the future.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6835428
Effective therapeutic approaches are lacking for ovarian carcinoma (OC), the most lethal gynecological neoplasm.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Effective", "therapeutic", "approaches", "are", "...
PMC11632064
Unpaired analyses refer to independent experiments that cannot be paired, such as different cell lines that have not been tested simultaneously.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Unpaire...
PMC6642070
Resting blood lactate levels of C57BL/6 J mice co-administered with lovastatin and DCA for 30 days (n = 10 each group). (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11607764
TP53, as a pivotal gene, frequently mutated in diffuse gliomas and particularly in astrocytic tumors.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "TP53", ",", "as", "a", "pivotal", "gene", ...
PMC11401350
CAR T cells incorporate a T cell receptor-like structure presenting at its surface a scFv of an antibody that binds to a cancer cell specific antigen .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11696659
Healthy subjects were selected in an independent process from two ongoing studies and included blood donors from two groups aged 40–65 years and >65 years.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9429973
L. Nastoupil, F. Morschhauser, C. W. Scholz, M. Bishton, S.-S. Yoon, P. Giri, M. C. Wei, A. Knapp, C.-C. Li, A. Bottos, H. Li, E. Purev, N. L. Bartlett Emory University, Atlanta, GA, United States of America; University of Lille, CHU Lille, Lille, France; Vivantes Klinikum am Urban, Berlin, Germany; Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom; Seoul National University Hospital, Seoul, South Korea; Royal Adelaide Hospital, Adelaide, Australia; Genentech, Inc., South San Francisco, CA, United States of America; F. Hoffmann-La Roche Ltd, Basel, Switzerland; Hoffmann-La Roche Ltd, Mississauga, ON, Canada; Washington University School of Medicine, St. Louis, United States of America Background: Despite significant progress with first-line immunochemotherapy, most patients with follicular lymphoma (FL) will eventually relapse with increasing refractoriness and decreasing duration of response to subsequent therapy lines (Rivas-Delgado et al. 2019).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11541241
Alignment of the TOR protein sequences from phytopathogenic fungi with those from S. cerevisiae and S. pombe showed similar conserved domain organization and high identification.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC8740518
IHC staining of adenocarcinoma marker MOC31 was negative. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "IHC", "staining", "of", "adenocarcinoma", "marker", "MOC31", "was", "negative", ".", "(" ] } ]
PMC9672323
The effect of dexamethasone and piroxicam was measured on the SOD3 activity (a) and TAC levels (b) of T cells in PBMCs (n = 3).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
University of Melbourne, Melbourne; Townsville University Hospital, James Cook University, Douglas, Australia; Keros Therapeutics, Lexington, United States of America Background: Myelodysplastic syndromes (MDS) are characterized by ineffective hematopoiesis; many patients develop high transfusion burden (HTB) requiring ≥4 units RBCs every 8 weeks and have high unmet medical need.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8481254
B, C WB analysis of O-GlcNAc levels (B) and LATS1, LATS2, MST1, MST2, OGT, YAP, SLC5A3, and Nudt9 (C) expression in Bel-7402 and Bel-7404 cells cultured in media containing the indicated concentrations of glucose for 24 h. D YAP, OGT, Nudt9, and SLC5A3 were analyzed by qPCR in Bel-7402 or Bel-7404 cells under the indicated treatments.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11629143
This study describes the epigenetic manipulation of the CMV promoter.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "study", "describes", "the", "epigenetic", "manipulation", "of", "the", "CMV", "promoter"...
PMC11531744
In addition, correlations containing pathway enrichment, treatment, immune cell infiltration and the prognostic model were also analyzed.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "addition", ",", ...
PMC9812014
NDV has a negative-sense ssRNA that is roughly 15 kb long and nonsegmented.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "NDV", "has", "a", "negative-sense", "ssRNA", "that", "is", "roughly", ...
PMC10758402
786-0 cells were treated as in (A) and at 36 hours post-infection, supernatants were collected and assayed by ELISA for IFN-β levels (N=3 mean ± SEM; *P < 0.05, **p < 0.01, ***P < 0.001 and ****p < 0.0001.
[ { "tags": [ "B-CellLine", "I-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"...
PMC11718809
The top 20 CC items include a cellular, anatomical entity, cellular_component, intracellular anatomical structure, etc. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "top", "20", "CC...
PMC9964654
The association of these complexes with nanosized carriers, such as polymers and micelles, could improve their solubility, pharmacokinetics, and in vivo circulation times, resulting in increased drug accumulation based on the EPR (enhanced permeability and retention) effect .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11680562
This hampers the organelle's capacity to generate ATP, the cellular energy unit.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "hampers", "the", "organelle", "'s", "capacity", "to", "g...
PMC11612794
Therefore, CENP-C cells enable the observation of CENP-T-bound Mis12C at the native kinetochore.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "CENP-C", "cells", "enable", "the", "observation", ...
PMC9964635
Analysis calculated for C23H28N4OS, C, 67.62; H, 6.91; N, 13.71; S, 7.85.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Analysis", "calculated", "fo...
PMC10565698
Herein, we demonstrate the existence of binding sites for miR-211-5p and TCF12.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Herein", ",", "we", "demonstrate", "the", "existence", "of"...
PMC10079526
U2OS cells were cultured in suspension and treated for 4 or 20 h with 1 µM 5-Aza-2’ or DMSO 0.1% control with or without MG132 10 µM for 4 h and 2.5 µM for 20 h. Total lysate input and His10-SUMO2- pulldown elutions were analyzed by immunoblotting using SMC6 antibody.
[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4839679
n = 5 independent biological replicate experiments.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "n", "=", "5", "independent", "biological", "replicate", "experiments", "." ] } ]
PMC10568263
In this study, the novel Au@MnO2/MoO3 nanocomposite was fabricated by the solution-mixing process and its structure, morphology, and elemental composition were analysed by transmission electron microscopy (TEM), X-ray diffraction (XRD), and X-ray photoelectron spectroscopy (XPS).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11489351
We show that pHi differentially regulates expression of master regulators of pyruvate fate (such as LDHA and PDK1), which serve to integrate the flux of the hub metabolite pyruvate through various pathways.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
The most prominent unexpected antibodies in the study belong to the Rh system (Anti-D).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "most", "prominent", "unexpected", "antibodies", ...
PMC11772449
E-G: Thecombination of Sora and pirfenidone reduced the expression level of Beclin-1 in hepatocellular carcinoma cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "E-G", ":", "Thecombination", "of", "Sora", ...
PMC11597167
The mixture was incubated at 50 °C for 50 min and 85 °C for 5 min.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "mixture", "was", "incubated", "...
PMC11695546
Some studies reported the anti-hemolytic potential of virgin coconut oil (Hmidani et al. 2021; Utarı et al. 2022).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Some", "studies", ...
PMC6450504
Free PTX groups were used as controls to evaluate the diffusion rate through the release membrane.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Free", "PTX", "groups", "were", "used", "as", "c...
PMC5035325
The tumors with the greatest number of patients (n > 6): NSCLC, nasopharyngeal, colorectal, renal and liver carcinoma showed co-expression (EGFR/NeuGcGM3) in more than 50 % of their tumoral cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11371747
Growth inhibition of the non-small cell lung cancer (NSCLC), colon cancer and malignant pleural mesothelioma (MPM) cell lines by 5-FU and the modulation by l-LV, d-LV and dl-LV, growth inhibition by PMX, RTX and PLX and the protection by l-LV was determined using the sulforhodamine B (SRB) assay as previously described (Keepers et al., 1991).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5035325
Other carcinomas with fewer patients (n = 2–5) also showed high percentage of EGFR/NeuGcGM3 positive cells: prostate, ovarian, cervical, breast carcinoma and glioblastoma multiform.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11541409
Mutations in the extracellular and cytosolic JM domains lead to the TKD being in an activation state, thus exempting the KIT mutants from the control of SCF.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11534035
The work of Ruckriegl et al. initially revealed a correlation between the activation status of GPER1 and changes in the expression of PAI1 in cervical cancer cell lines (12).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8557138
These channels can then be implanted with endothelial cells for the formation of a functional vascular system (Miller et al. 2012; Grebenyuk and Ranga 2019).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11025866
Exposure of cells to the HDACi butyrate leads to increases in the expression of thousands of cellular genes .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Exposure", "of", "cells", "to", "the",...
PMC11705862
Statistical analysis of changes between NC vs. AD and NC vs. T2D was performed using two-tailed student T-tests, with error bars indicating standard deviation (SD).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11499381
indicates P < 0.05 compared with WT as determined by repeated measures one-way ANOVA with a post-hoc Dunnett's test comparing all conditions to WT at each time point. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6163708
Other melanoma cell lines (MeWo, SK-MEL-2, SK-MEL-28, SK-MEL-5, SK-MEL-3, Malme 3M, HT144, WM35, WM1552C, and RPMI-7931) were purchased from American Type Culture Collection (ATCC) (Manassas, VA, USA).
[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "B-CellLine", "O", "B-CellLine", "O", "B-CellLine", "O", "B-CellLine", "I-CellLine", "I-CellLine", "O", "B-CellLine",...
PMC6892818
b ACHN, 786-O and A-704 cells were treated with mCD40L for the indicated time periods (6, 12 and 24 h) and expression of Bak and Bax was detected in controls (‘C’) vs. mCD40L-treated cells (‘mL’) by immunoblotting (40 µg protein/lane).
[ { "tags": [ "O", "B-CellLine", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"...
PMC9429973
Death by respiratory distress in 15 cases (48%) originating from: intra-alveolar hemorrhage, PAO and hypoxemic infectious pneumonitis in 7, 4 and 4 cases respectively.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10335954
Recent epidemiological studies have shown decreased incidence and mortality of gastric malignancy worldwide (Luo et al. 2017), but the yearly cost of its treatment still remains high because of the lack of effective therapy (Thrift and El-Serag 2020).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11680562
A comprehensive optical property analysis was conducted utilizing a UV–Vis spectrometer to examine green synthesized CuO NPs.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "comprehensive", "optical", "...
PMC11626627
Validation of the effects of circATP2B1 and TWIST1 using Western blotting in A498 cells transfected with pWPI+pLVTHM, sh-circATP2B1#1+pWPI, sh-TWIST1#1+pLVTHM, and sh-circATP2B1#1+sh-TWIST1#1.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "token...
PMC9429973
Throughout the next month as she remained at the hospital for investigation, she had been febrile with no germen identification and no improvement despite multiple antibiotic courses.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10890055
The human fetal osteoblast cell line hFOB 1.19 is a very promising cell model; however, there are vast discrepancies in cultivation protocols, especially in the cultivation temperature and the presence of the selection reagent, geneticin (G418).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC11612626
Any abnormalities, including weight loss, change in behavior, or signs of illness, were recorded and veterinary care was sought.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Any", ...
PMC11047729
The roles of telomeres and telomerase in driving uncontrolled cellular proliferation, immortalization, and the onset of cancer are pivotal.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "roles", "o...
PMC10847511
This is likely because cells deficient in HR function use alternative DNA repair pathways to repair DNA damage while the cell cycle checkpoint is activated and proliferation is halted.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
The data was analyzed using GraphPad software and the data expressed as Mean ± SD.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "data", "was", "analyzed", "using", "GraphPad", "soft...
PMC9318744
SARS-CoV-2 has infected more than 530 million people and caused over 6.3 million deaths to date (9 June 2022) since its first outbreak in December 2019, according to the WHO Coronavirus (COVID-19) Dashboard .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
In total, the MRD negativity rate increased from 55% to 76% Image: Summary/Conclusion: Before KRd consolidation, 33% of patients in VGPR or better after first line treatment including ASCT were FDG PET/CT positive.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11576293
To validate the docking study, Erlotinib (for 1M17 as crystal structure of EGFR) and Sorafenib (for 3WZE as crystal structure of VEGFR-2 ( were docked into the binding site using a set of parameters of minimization via MMF94FX forcefield with gradient RMS of 0.0001 kcal/mol.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10747139
Some complexes were potent inhibitors of essential SARS-CoV-2 targets, such as the SARS-CoV-2 spike protein/host ACE2 receptor interaction and the SARS-CoV-2 papain-like protease (PL).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11782780
Primers used are listed in Table 1.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Primers", "used", "are", "listed", "in", "Table", "1", "." ] } ]
PMC11748618
Therefore, an effective strategy at ensuring the long-term efficacy of ART could include the addition of safe, effective therapeutics that reduce the likelihood of HIV antiviral resistance.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
There was no correlation with AML subtype or risk.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "There", "was", "no", "correlation", "with", "AML", "subtype", "or", "risk", "." ] } ]
PMC10452486
KIR3D includes domain 0 (D0), D1, and D2, whereas KIR2D may have D0 and D2 or D1 and D2.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11806106
As previous studies showed that the development of a functional and reliable µ opioid receptor sensor is problematic, especially the correct expression of the sensor at the plasma membrane, we inserted the fluorophores at different positions in the third intracellular loop (Fig. 1A).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10847511
Spearman’s correlation between mutational signature 3 value and the area under the drug-response curve (AUC) was analyzed.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Spearman", "’s", "correlatio...
PMC5417661
Moreover, the fate of each mitotic cell that was used to calculate the length of cell division was recorded.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "the", ...
PMC7504302
Similarly, the loss of function of BAP1 resulted in chemoresistance to RNR inhibition, suggesting that the BAP1 status may define a synthetically lethal genetic vulnerability, and could be a predictor of therapy response .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC2193049
We tested whether the peptide fragments obtained after exposure of NH2- and COOH-terminally extended MAGE-3271–279 precursors to purified human proteasome correlated with the results obtained using transfected cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11190238
Earlier studies have shown that PRC2 subunits co-orchestrate with EMT TFs during the epigenetic reprogramming of EMT.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Earlier", "studies", "have", "shown", "that", ...
PMC11409031
In Supplementary Table 1, we also show that these 44 differential prognostic genes correlate with the prognosis of OV patients.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "Supplementary", ...
PMC11802929
TCR group density calculations were implemented this same methodology.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "TCR", "group", "density", "calculations", "were", "implemented", "this", "same", "methodology", "." ] ...
PMC8873393
Where there are several CDS isoforms in a gene, they are all counted.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Where", "there", "are", "several", "CDS", "isoforms", "in", "a",...
PMC6024716
Limiting dilutions were carried out from each well, as previously described , in 96-well plates.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Limiting", "dilutions", "were", "carried", "out", "fro...
PMC8806312
These results establish the basis for the follow-up OS immunotherapy.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "results", "establish", "the", "basis", "for", "the", "follow-up", "OS", "immunotherapy"...
PMC11507371
Given NF-κB’s redox sensitivity and association with apoptosis, NF-κB, alongside its inhibitor IκBα, were analysed as well.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Given", "NF-κB", ...
PMC10671321
In vivo, the abnormal D-CTD could also impair the interaction with perlecan, but this is very unlikely (1) because perlecan binds to the HBS in the collagen domain and the conformation of the triple helix is normal; and (2) variants in this D-CTD do not affect the interaction with perlecan .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11674146
P < 0.05; **P < 0.01.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "P", "<", "0.05", ";", "*", "*", "P", "<", "0.01", "." ] } ]
PMC7802142
ReN cells were purchased from Millipore (USA).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ReN", "cells", "were", "purchased", "from", "Millipore", "(", "USA", ")", "." ] } ]
PMC10578720
This conditioned medium was used as a control for in vitro experiments.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "conditioned", "medium", "was", "used", "as", "a", "control", "for", ...
PMC9813422
Cellular factors for the maintenance of viral episomes have not been well addressed.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cellular", "factors", "for", "the", "maintenance", "of", "viral", "episomes...
PMC11732635
The patient received a conditioning regimen of fludarabine and cyclophosphamide and an intravenous infusion of gp350-targeted chimeric antigen receptor T (CAR T) cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11286266
FURIN cleavage assay.
[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "FURIN", "cleavage", "assay", "." ] } ]
PMC11194678
The methods followed were described previously (Shan et al., 2018).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "methods", "followed", "were", "described", "previously", "(", "Shan"...
PMC6182045
This cell line, produced using robotic selection, expresses high levels (1.2 g/L) of the TZ97008 rgp120 antigen that incorporates oligomannose glycans required for binding to multiple glycan dependent bNAbs.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11725127
The cells were harvested, washed with PBS, and lysed by 2 × SDS buffer.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cells", "were", "harvested", ",", "washed", ...
PMC11295144
The cells were washed with HBSS and the HRP activity was detected using tetramethylbenzidine reagent (TMB, 34028, Thermo Scientific).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...
PMC11772449
The World Health Organization estimates that more than 1 million people will die of liver cancer in 2030 (Geneva 2016).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "World...
PMC6889484
Western blot analysis of puromycin-resistant CEM/D128K and PM1/D128K cell lines (n = 5).
[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Western", "blot", "analys...
PMC10674574
Therefore, using the Caco-2 cell line in the pharmaceutical industry requires the validation of this biological model to demonstrate its suitability for the intended purposes (e.g., classification of substances into a BCS group).
[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Auditing CUH performance against the NICE CG143 guidelines, it was found that initial pain relief was provided within 30 minutes of presentation in 15 out of the 21 relevant admissions (71%).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11012012
SLAMF1/CD150, SLAMF2/CD48, and SLAMF7/CD319 were found to be downregulated while SLAMF3/CD229, SLAMF5/CD84, and SLAMF6/CD352 were overexpressed in CLL.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "SLAMF1/CD150", ...
PMC11541241
ATGs are identified in all the species investigated, indicating the conserved role of autophagy in the fungal kingdom.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ATGs", "are", "identified", "in",...
PMC11787381
Tubes were weighed individually before and after sampling, and immediately transferred to a −20 °C freezer.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Tubes", "were", "weighed", "individually", ...