Datasets:
OTAR3088
/
BioData-CellLine_annotated

Dataset card Data Studio Files
xet
 Community
1
PMCID
string
Sentences
string
ner
list
PMC9429973
Pts who had an HLA-matched donor and at least stable disease were encouraged to undergo HSCT after ≥1 treatment cycle.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Pts", "who", "had", "a...
PMC3813807
To examine the effect of miR-373 on endogenous TNFAIP1 expression, miR-373 mimics were transfected into HGC-27 cells, which are known to express high levels of TNFAIP1 protein.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10808409
It was also reported to have a significant cytotoxic effect in multidrug-resistant cell lines, as it inhibits the P-glycoprotein drug efflux transport system, which is usually overexpressed in multi-drug resistant cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10728200
After 2 hours, the 96-well plate was oscillated for 2 min.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "2", "hours", ",", "the", "96-well", "plate", "was", "oscillated", ...
PMC10723784
The samples were diluted in PBS to 1 × 10 cells/mL and 2.5 μg/mL of JC‐1 dye was added to each sample.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "sampl...
PMC11301242
Genome-wide map of ecDNA and linear amplification peaks.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Genome-wide", "map", "of", "ecDNA", "and", "linear", "amplification", "peaks", "." ] } ]
PMC9429973
Figure 1 shows the frequency of M-GVs found in the MYSEC cohort, distinguished by SMF subtype (a) and driver mutations (b).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC6643347
The transmission rate depends on both the expression level of the cellular surface receptors and the viral strain .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "transmission", "rate", "depends", ...
PMC11612508
This synergistic effect promotes apoptosis in vitro in 4T1 breast cancer cells and effectively inhibits tumor growth in 4T1 tumor xenografts, making DOX-MMS a potent delivery system for efficient magnetic-responsive drug release and combined chemo-thermal therapy.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "...
PMC10907726
This work was funded by 10.13039/501100004608Natural Science Foundation of Jiangsu Province (2022 BK20220464, BK20221420), Jiangsu Provincial Traditional Chinese Medicine Science and 10.13039/100006180Technology Development Plan Project (2020 ZD202008), Science and technology projects in Jiangsu Province (2019 BE2019765), Postgraduate Research & Practice Innovation Program of Jiangsu Province (2022 SJCX22_0854) and Natural Science Foundation of 10.13039/501100007956Nanjing University of Chinese Medicine (2022 XZR2021028).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8097906
The transcript level of the tumor stem cell marker prominin (CD133) was generally negatively affected by an expression decrease with an average of 20–30% at VSM concentrations in a range of 10–100 μg/ml.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5311252
The curved gradient (curve 6 in the Chromeleon software) then proceeded from 3% mobile phase B (90% acetonitrile, 5% dimethylsulfoxide, 5% water, 0.1% formic acid) to 45% B in 50 min followed by wash at 99% B and re-equilibration.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11655536
Importantly, HA induced apoptosis of the carfilzomib-resistant MM cells and enhanced the effect of carfilzomib in MM.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Importantly", ",", "HA", "induced", "a...
PMC11657695
KCNA2 expression in patients and cell lines was measured via bioinformatic analysis (RNA-Seq).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "KCNA2", "expression", "in", "patients", "and", "cell", "lin...
PMC10988555
After incubation, the plasmid DNA (pDNA) was extracted by using the Kit NZYSpeedy Miniprep, following the instructions provided by the manufacturer.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11680982
Images were obtained with a microscopy system (Leica-DM6000B, Germany).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Images", "were", "obtained", "with", "a", "microscopy", "system", "(", "Leica-DM...
PMC11640476
Regardless of the method employed to assess cellular responses to treatment, the obtained results should consistently align.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Regardless", "of", "the", "method", "e...
PMC11782508
Untreated control cells. (
[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "Untreated", "control", "cells", ".", "(" ] } ]
PMC11173119
Karyotype analysis was performed as described earlier .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Karyotype", "analysis", "was", "performed", "as", "described", "earlier", "." ] } ]
PMC9545474
Compounds 6 and 8 were chosen for in vivo preclinical studies based on their in vitro potential.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Compounds", "6", "and", "8", "were", "chose...
PMC9429973
Results: Patients with CTX with CIPN showed significant endothelial dysfunction compared to controls (StO2 downslope -7 ± 2%, T95(s) 13 ± 5, PIRH-AUC 9 ± 6, p<0.05 each) and CTX without CIPN (p<0.05 each), much like PAD.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11422497
By selectively inhibiting the activity of mutant c-kit and PDGFRα receptors, imatinib effectively suppresses tumor growth and prolongs survival in these patients.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "By", ...
PMC11629461
Much effort has been made in the research and development of both pan‐NOX and type‐specific NOX inhibitors. ,
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Much", "effort", "has", "been", "made"...
PMC11283030
Excessive lipids are secreted as lipoproteins or stored in lipid droplets (LDs) as the energy source .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Excessive", "lipids", "are", "secreted", ...
PMC10938377
The click reactions between 5 and each of the peptides (L1–L4) were conducted in tert-butyl alcohol and milliQ water in the presence of 1 mol% Cu(ii) sulphate and 10 mol% sodium ascorbate in millQ water (Scheme 2).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10604092
While cancer cachexia causes malnutrition-like symptoms, such as loss of body weight and reduction in food intake, it differs from starvation and simple malnutrition, both of which can be easily treated by providing appropriate nutrients.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11727062
This is achieved by inducing autophagy and CyclinD3-dependent cell cycle arrest, which enhances the sensitivity of the tumor cells to the chemotherapeutic agent.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973
Together with impairment of aerobic glycolysis, YKL-5-124 treatment resulted in increased ROS levels and induction of apoptotic cell death.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Together", "...
PMC9920575
Additionally, similar results were obtained when 0.3 µg/mL and 0.6 µg/mL of the antineoplastic agent cisplatin were used in HeLa and HaCaT cells, respectively.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "...
PMC11757131
Autophagy is the process of intracellular degradation and recycling of cellular components, and is important for maintaining cellular homeostasis and adapting to environmental changes (34).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Per the Yost index, 24.8%, 33.8%, and 41.4% of patients were in Groups 1, 2, and 3, respectively.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11733919
Each sample was measured five times at 25 °C, combining 10 runs per measurement.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Each", "sample", "was", "measured", "five", "times", ...
PMC9429973
More than half of the OHI+ patients died from non-malignant causes (39% multi-organ dysfunction or HLH, 18% infection), while most OHI- patients (92%) died from progressive malignancy.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11461874
Statistical significance was determined for genotype, time and interaction by two-way ANOVA.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Statistical", "significance", "was", "determined", "for", "genotype", ",", ...
PMC9583612
The goal of this verification should encompass both evaluating the validity of direct measurements and providing robust uncertainty bounds on emissions based on operational and maintenance records, emission and activity data, and an inventory estimate that has been reconciled with measurements.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11413393
f, g Scatter plots of γH2AX foci in RCC243 cells treated with and without MS023 (f) or with dox-inducible PRMT1-shRNAs treated with or without Dox (g) for indicated times.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9275501
Reprinted with permission from American Chemical Society (Anwar et al., 2018).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Reprinted", "with", "permission", "from", "American", "Chemical", "Soc...
PMC4485786
Primary antibodies against the following proteins were used: CD3 (SP7, 1:50; DCS Innovative Diagnostic Systeme GmBH, Germany); monoclonal rabbit anti human CD4 (SP35, 1:50, Zytomed Systems); CD8 (C8/144B, 1:100), CD56 (123C3-D5, 1:20), CD68 (PG-M1, 1:150), HLA-DR-α (TAL.1B5, 1:200), desmin (D33, 1:100) (DAKO, Germany); perforin (5810, 1:200, Novocastra/Leica, Germany).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10135767
During this process, intracellular calcium signals are generated .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "During", "this", "process", ",", "intracellular", "calcium", "signals", "are", "generated", "." ] } ]
PMC3203927
The optimal polymer/salt/solvent ratio of 1∶20∶5 (w/w/v) as determined in Cheng et al. was used to generate the paste mixture.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "optim...
PMC11752767
Although many hurdles remain to be overcome in the clinical application of TCR-T therapy, it is more satisfying in solid tumors than CAR-T therapy .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973
Hypercoagulable syndrome (increase of fibrinogen, D-dimer, FVIII, VWF, and decrease of ATIII) was registered in 18 (78%) patients, significantly more frequently than in Group №2 patients (11 patients - 42%; p=0,01).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11365427
This indicates that phenylalanine deprivation limits the rapid proliferation of MM cells, as evidenced by the arrest of the cell cycle.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "indi...
PMC11720107
Similarly, Siegers et al. reported that garlic extracts inhibited cancer cell proliferation, as measured by the same test, at a concentration of 0.330 mg/mL in the human hepatoma cell line (HepG2) and 0.480 mg/mL in the CACO-2 cell line.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11089031
indicates P < 0.05; ** indicates P < 0.01; *** indicates P < 0.001; **** indicates P < 0.0001 The results of statistical analysis of the expression levels of ZNF692 in ccRCC N.S.: No statistical significance (P > 0.05).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
GEPs analysis highlighted increased expression of IR-ligands like CD274, CEACAM1, CD48 on granulocytes from MF patients compared to HDs.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "GEPs", "analysis", ...
PMC7504302
Homozygous deletions of the CDKN2A (cyclin-dependent kinase inhibitor 2A) locus, specifically 9p21, have been demonstrated to be frequent in many primary tumor types of different origin.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Results: Of 3250 abstracts identified, 34 publications describing 16 studies met inclusion criteria: 5 randomized controlled trials (RCTs), 3 prospective studies, and 8 retrospective studies.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Summary/Conclusion: Our results indicate that indisulam is preferentially active and synergistic with venetoclax and azacitidine in SF3B1-mutated cells from newly diagnosed, non-treated AML patients.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC3274243
Analysis of the OCP generated by the confluent cell cultures prior to treatment (data not presented) showed that RSF generated a mean OCP of 112 mV (SD ± 7 mV) and HepG2 169 mV (SD ± 10 mV) whereas cell-free sensors produced 54 mV (SD ± 9 mV) and 6 mV (SD ± 17 mV) respectively.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", ...
PMC11707577
Scale bar = 20 µm.
[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bar", "=", "20", "µm", "." ] } ]
PMC11779605
Using IPA, 26 pathways were identified to be significantly different in the tumor compared to those in the ascites specimens ( Figure 1E , Supplementary Table S4 ).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11741577
To determine if growth factor or cytokine secretion was elevated in HMC-1 CM and FSL-1-HMC-1 CM, we used a cytokine array analysis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens"...
PMC11656380
We used the fluorescent dye JC-1, which shifts from green to red emission in response to changes in membrane potential, to assess mitochondrial depolarization.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC8345486
Next, the cells were collected from different culture conditions and seeded into appropriate 24-well and 96-well plates (3 × 10 and 2 × 10 cells/well, respectively) for 24 h, followed by treatment with the following drugs: cisplatin, carboplatin, paclitaxel (PTX), doxorubicin (DOX), or gemcitabine (GEM) for 24 h and 48 h (at IC50 and half IC50).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11609529
This reduction was consistent with the decreased weight of peritoneal tumors collected from the shM2-3 group compared to the control group (Figure 6B).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11538390
In Finland the prevalence of births with CL/P over the period 2000–2014 was 1.08 per 1000 births, whereas the prevalence of CP was 1.50 per 1000 births.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Patients will be treated with aza at 75 mg/m IV/SC daily on days 1-7, ven on days 1-28 per VENCLEXA USPI, followed by tamibarotene at 6 mg twice per day by mouth on days 8-28 of each 28-day cycle.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11794847
Nevertheless, HE staining of the lungs showed that HVEM KO group was more severe than wild type group (Figure S6A–D).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11758416
Resuspend centrifuged cells in 1 mL of fresh L cell media.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Resuspend", "centrifuged", "cells", "in", "1", "mL", "of", "fresh", "L", "cell", ...
PMC10812665
Altered levels and localizations of this post-translational modification are found in many neurodegenerative diseases .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Altered", "levels", "and", "localizations", "of", "this", "post-transl...
PMC11803918
After 8 days of A375 tumor cell implantation, different treatments were given to humanized mice as illustrated in Figure 8A.
[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "8", ...
PMC11453018
A notable increase in β-Gal-positive cells was detected in SKES1 and TC71 24 h after iP300w treatment, even in the absence of evident morphological changes at this stage (Fig. 5A; Supplementary Fig. 5A).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC9856122
This BBI alkaloid was found responsible to inhibit IL-6 in the cornea of mice and thus exerts inhibition against HSV .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "BBI", "alkaloid", ...
PMC9429973
Risk was stratified according to the DIPSS in PMF and according to the MySEC-PM in SMF patients.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Risk", "was", "stratified", "according", "to", ...
PMC11756514
The QPD motif confers a galactose-type specificity recognizing a combination of an equatorial 3-OH and an axial 4-OH group (6).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "QPD",...
PMC11532793
The read count distribution therefore follows a mixture distribution across biological replicates with a quadratic mean-variance relationship of the form The RTA dispersion τt depends on the annotation topology of the gene that the transcript belongs to whereas and ψt depend on the biological samples and on the sequencing technology.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11536589
Treatment with 1 mg/kg MRTX1133 results in significant suppressing of tumour growth and the tumour weight in MGST1 KO group (Fig. 7G).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11777207
The predicted change in total PD-L1 solvent accessible surface area is 3498.2 to 2838.4 Å, demonstrating a likely favorable interaction (Fig. 5B).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC8010066
Similar results were reported by Limoli et al. (2016) and Tognon et al. (2019).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Similar", "results", "were", "reported", ...
PMC11537649
The correlation analysis indicates that CDK6 is positively correlated with Lnc NEAT1 and negatively correlated with miR-152-3p (Fig. 5B and C).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973
Methods: In this single-center retrospective analysis we reviewed the charts of patientes who received ruxolitinib for cGvHD between January 2017 and December 2021 in Hospital Álvaro Cunqueiro, Vigo.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10198699
An example of this would be if the research institution represented to present-day Henrietta Lacks that she would retain ownership of her donated tissue sample, while in fact (because of the restriction imposed by the NHA) it is a legal impossibility.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10440586
To further explore the association between CD99 and the glioma TME, we analyzed different cell fractions to confirm the major cell type influenced by CD99.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11519583
Breeding colonies were kept at 22–25 °C and humidity of 40–65%.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Breeding", "colonies", "were", "kept", "at", "22–25", "°", "C", "and"...
PMC11650848
Specific cellular machinery protects the epigenetically marked ICRs from reprogramming.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Specific", "cellular", "machinery", "protects", "the", "epigenetically", "marked", "ICRs", "from", ...
PMC11574271
Moreover, we studied the role of certain microRNA species (miRNAs) as endogenous regulators in modulating RON expression and its associated tumorigenic activities in bladder cancer cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10114490
Control Liver RNA sample was obtained by combining human liver total RNA (ThermoFisher) from three donors.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Control", "Liver", "RNA", "sample", "w...
PMC10914904
Inhibiting these MVPs not only reduces the expression of differentiation markers on dendritic cells but also decreases their ability to induce antigen-specific T-cell proliferation and interferon-γ release.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Median number of apheresis days was 1 (IQR 1-2) in pts not requiring PLX and 2 (IQR 1-2) in pts requiring PLX.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10933092
Taken together, these data demonstrated that TRMT61A was required for the mA modification of both mRNAs and lncRNAs through the AGGCUG motif.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Taken",...
PMC9780037
Gene therapy has been successful in delivering therapeutic genes to the patient, for in vivo production of therapeutic proteins.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Gene", "therapy", "has", ...
PMC6835428
Particles with smaller size will be predominantly cleared via the lacunar route, and the very small particles (nm range) will be mostly drained by blood vessels.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10530622
The study associated five different antibiotics with increased odds of nephrolithiasis .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "study", "associated", "five", "different", "antibiotics", "with", "increased", "odds...
PMC11095939
It is worth noting that, other than accelerated cell cycle reentry, Mecp2 cKO hepatocytes also displayed a modest increase in cell size with enlarged nuclei relative to control cells (Figure 2—figure supplement 1G), implying the attenuation of mitosis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11609529
Scale bars: 100 μm (top) and 25 μm (bottom).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bars", ":", "100", "μm", "(", "top", ")", "and", ...
PMC9786247
All strains were isolated from different animals.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "strains", "were", "isolated", "from", "different", "animals", "." ] } ]
PMC9429973
However, the effectiveness of vaccination in self-transplanted patients seems to be variable.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "the", "effectiveness", "of", "vaccination", "in", "self-tra...
PMC10376064
Inhibition of ABCC1 would sensitize H69AR cells, resulting in less doxorubicin necessary to impair H69AR cell viability.
[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O" ], "tokens": [ "Inhibition", "of", "ABCC1", ...
PMC10114490
All types of HDF and iHDF cells were cultured in DMEM containing 10% fetal calf serum.
[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "types", "of", "HDF", "an...
PMC11190538
The resulting higher shear stress increased their viscosity compared with the control.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "resulting", "higher", "shear", "stress", "increased", "their", "viscosity", ...
PMC9429973
Variances between mice were rather small, with few exceptions for some treated mice.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Variances", "between", "mice", "were", "rather", "small", ",", "...
PMC10376064
Thus, we assessed the potential of DMF and its metabolite MMF to modulate the AD-associated ABC transporters ABCB1 (P-glycoprotein, P-gp), ABCC1, (multi-drug resistance-associated protein 1, MRP1), and ABCG2 (breast cancer resistance protein, BRCP1) in vitro.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10006224
This residence time depends on ESCO1 and CTCF but we here show that KD of any of these two factors along with NIPBL does not modify the results of single NIPBL KD.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11632064
Viability of cells treated with 10 μM BI 6727 for 24 h. (N, O) CXCL8 and IL6 transcript levels in MeWo and MeWo-Rho-0 cells treated DMSO 0.1% and inhibitors at the indicated doses for 72 h. Data are shown as mean ± SEM of three or more independent experiments. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLin...
PMC11721064
The capacity to adhere to type IV collagen is recognized as a crucial characteristic of epithelial cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "capacity", "to", "adhere", "to", "ty...
PMC7185206
A model of ADAM10/ADAM17-induced sPD-L1-mediated PD-(L)1 resistance is diagrammed (e).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "model", "of", "ADAM10/ADAM17-induced", "sPD-L1-mediated", "PD-(L)1", "resistance", ...
PMC4360730
These slims provide an overview of the specific terms that have been used to annotate a set of genes.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "slims", "provide", "an",...
PMC10996034
For the IF assay, the medium was aspirated, and the cell crawls were washed three times with cold PBS.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "the", "IF"...
PMC8140214
As shown in Figure 2, after both 48 and 72 hr, 30 mM D-glucose significantly increased SOD activity, but 50 mM D-glucose decreased it though itwas significant only after 72 hr of treatment with 50 mM D-glucose (p<0.05).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...