Datasets:
OTAR3088
/
BioData-CellLine_annotated

Dataset card Data Studio Files
xet
Community
1
PMCID
string
Sentences
string
ner
list
PMC11621565
However, it is currently premature to assert a causative relationship between the onset of PD and alterations in gut microbiota.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "i...
PMC11637820
Endosomal TLR3 and TLR9 recognize double-stranded DNA and CpG bacterial DNA, respectively .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Endosomal", "TLR3", "and", "TLR9", "recognize", "double-stranded", "DNA", "...
PMC9592219
Wang et al. confirmed that TOP2A in cervical cancer promotes EMT in tumor cells through the PI3K/AKT signaling pathway, which leads to tumor metastasis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10898159
Additionally, these KIT auto-regulation positive loop mediated by the components of the PI3K or MAPK signal pathways strengthened the interest in the conjoined inhibition of these two pathways as potential therapeutic strategy, thus support the continuous endeavor for the development of novel drugs in this field in the setting of IM-resistant GIST, although how to decrease the toxicity of these combination is a key unanswered question.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11585565
Relative mRNA levels of wild-type and mutant CNNM4 at 24- and 48-hours post-transfection.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Relative", "mRNA", "levels", "of", "wild-type", "and", "mutant", "CNNM4", ...
PMC11772585
However, CSCC exhibits higher malignancy compared to basal cell carcinoma, with increased metastatic and invasive capabilities .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "CSCC", "exhibits", "hi...
PMC11684297
ZnO nanoparticles synthesized using clove and ginger have been shown to be exerting anti-inflammatory effects .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ZnO", "nanoparticles", "synthesized", "using", "clove", "and", ...
PMC8584666
Recent studies have discovered a relationship between glycosylphosphatidylinositol (GPI)-anchored protein 80 (GPI-80)/VNN2 (80 kDa GPI-anchored protein) and malignant tumors.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Recent", "studies", ...
PMC11786767
As previously described (33), after 4-fold expansion, both cytoplasmic components and nuclear structures of the COS-7 cells expanded isotropically, regardless of their cell cycle stages (Fig. 1A, postexpansion).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", ...
PMC10452486
Interestingly, the HLA-G dimer in circulation was higher in a group of 90 patients with a functioning allograft compared with 40 patients who underwent allograft rejection.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11391695
Conversely, si-ACYP2 + si-TERT resulted in an increase in telomere length in these cells (Fig. 4I).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Conversely", ",", "si-ACYP2", "+"...
PMC11464982
The highest dietary exposure was estimated to be about 0.006 mg TOS/kg bw per day in children at the 95th percentile.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "highest", ...
PMC11748335
Moreover, our earlier analyses have revealed that short LOCKs harbor a greater fraction of promoter-TSS sites (Fig. 1D).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "...
PMC8068766
In addition to this intrinsic effect, an acquired mechanism might be at work due to the absence of Se.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "addition", "to", ...
PMC11188874
Shown is the arithmetic average of proteasome hydrolysis of LLVY-R110.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Shown", "is", "the", "arithmetic", "average", "of", "proteasome", "hydrolysis", "of", "LLVY-R110...
PMC11463018
Then, 19 was delivered to NCI-60 for the detailed examination of antitumor spectrum against different cancer cells include leukaemia, non-small cell lung cancer (NSCLC), colon cancer, CNS cancer, melanoma, ovary cancer, renal cancer, prostate cancer and breast cancer.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11693599
ELISA analysis showed that the protein levels of exosomal CD109 derived from pOC #1 and #2 were 34.1 ± 8.8 and 56.3 ± 1.8 ng/ml, respectively (Fig. 4D).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11392912
The study protocol is complied with the Declaration of Helsinki, approved by the ethical committee of Council of Scientific & Industrial Research-Institute of Genomics & Integrative Biology (CSIR-IGIB), New Delhi, India, and All India Institute of Medical Science (AIIMS), New Delhi, India (CSIR-IGIB/IHEC/2017-18 Dt.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10578720
DCA facilitates HBV clearance and delays the development of liver fibrosis in the chronic HBV-infected mouse model. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "DCA", "facilitates", "HBV", "clearance", ...
PMC11638288
In the absence of NKp46, the progression of diabetes is impeded.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "the", "absence", "of", "NKp46", ",", "the", "progression", "of", "di...
PMC11656657
Tumor-derived CXCL8 was reported to be a potent chemotactic factor for neutrophils, myeloid-derived suppressor cells (MDSCs) and monocytes, which are considered immunosuppressive components in the TME .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11786600
This is because too much PF-127 caused the fibers to become coarser and more wrinkled (Figure S3), which increased the roughness and density of the fibers; thus, the fibers absorbed liquid very slowly.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11380329
These results demonstrate a CI value < 1 at IC50, revealing a synergistic relationship between the different types of P and Vit D at IC50 levels in the OVCAR4 cell line (Table 2).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Humoral responses were evaluated by testing SARS-CoV-2 spike receptor binding domain (RBD) specific Ig.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Humoral", "responses", "were", "evaluated", "by", "tes...
PMC11484188
The concentration of nucleic acids used for transfection was 50 nM. The transfection was conducted at room temperature for 20 min for the complex formation, and then cells were incubated at 37˚C in a 5% CO2 incubator.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10329074
The YBX protein family exhibited remarkable sequence homology across diverse species.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "YBX", "protein", "family", "exhibited", "remarkable", "sequence", "homology", "acros...
PMC11721096
The fishing assay was carried out as outlined in Section 3.6, affording the final eluate which was referred to as mS5.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "fishi...
PMC11703992
Additionally, the robustness of the study and potential heterogeneity were investigated via the Cochran’s Q test .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "the", "robustness", ...
PMC11317131
The pegRNA contains a 5′ spacer sequence that directs PE5 to nick the target sequence (Supplementary Figure S1a).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "pegRNA", "contains", ...
PMC10713411
Similar to autophagy, inflammatory PCD modalities such as necroptosis and pyroptosis have a complicated relationship with cancers, causing both tumor progression and suppression .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9895440
Next, Teff or Tex were added either at an effector to target E:T ratio of 1:1 for the killing readout or 4:1 for the IFNγ ELISA readout (to stay in detectable range for both assays).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11766332
From a literature search, we considered 64 miRNAs consistently deregulated in ASD patients (ASD-miRNAs).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "From", "a", "literature", "search", ",", "w...
PMC11763126
GO analysis revealed that these peptides might be involved in cancer-related biological processes, including chromatin silencing, mesenchyme migration, and transcriptional misregulation in cancer (Fig. 1C).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11653552
The y-axis reports the normalized reads counts derived from the transcriptome of each patient and are expressed as transcripts per million (tpm) Box-plots showing the enrichment of TAZ, Che-1 (A), and YAP (B) gene expression by the three different ISS related to the selected CoMMpass patient cohort (N = 687).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11748335
We used the narrowPeak file as input for the CREAM R package, defining the identified regions as long LOCKs (≥ 100 kb) and short LOCKs (< 100 kb) respectively.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8164677
Acetyl transferase Tip60 was also selected as potential target.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Acetyl", "transferase", "Tip60", "was", "also", "selected", "as", "potential", "target", "." ] } ]
PMC10606998
In the literature, the action of Auger electrons, when their emitters are located directly in the cell nucleus, is compared with the action of alpha particles .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11127909
The results showed that the expression of EFHD1 could be strongly induced by cisplatin in 143B and MG63 cells (Figs. 1E, F, S1).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "...
PMC7759933
The selected genes: ALB (albumin, Hs00910225_m1); AFP (α-fetoprotein), Hs00173490_m1; ALDH3A1 (aldehyde dehydrogenase 3 family member A1), Hs00964880_m1; TOP2A (topoisomerase 2-α), Hs01032137_m1; PCNA (Proliferating cell nuclear antigen), Hs00427214_g1; KI67 (cellular marker for proliferation), Hs01032443_m1; CCND1 (encodes the cyclin D1 protein), Hs00765553_m1; CDKN1A (Cyclin Dependent Kinase Inhibitor 1A), Hs00355782_m1; CYP1A2 (cytochrome P450 family 1 subfamily A member 2), Hs00167927_m1; CYP1A1 (cytochrome P450 family 1 subfamily A member 1), Hs01054797_g1; CYP3A4 (cytochrome P450 family 3 subfamily A member 4), Hs02514989_s1; AHR (aryl hydrocarbon receptor), Hs00169233_m1; UGT2B7 (UDP glucuronosyltransferase family 2 member B7), Hs00426592_m1; UGT1A1 (UDP glucuronosyltransferase 1 family, polypeptide A1), Hs02511055_s1; SULT1C2 (sulfotransferase family 1C member 2), Hs00602560_m1; SULT1B1 (sulfotransferase family 1B member 1), Hs00234899_m1; NAT1 (N-acetyltransferase 1), Hs02511243_s1; NAT2 (N-acetyltransferase 2), Hs01854954_s1; HIF1α (Hypoxia-inducible factor 1-alpha), Hs00153153_m1; BBC3 (p53 upregulated modulator of apoptosis), Hs00248075_m1 were pre-amplificated.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10919056
PFS analysis results in the training set. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "PFS", "analysis", "results", "in", "the", "training", "set", ".", "(" ] } ]
PMC10674574
The TEER vales in the range of 500–1100 ohms are considered acceptable for fully differentiated cultures .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "TEER", "vales", "in", "the", "range", "of...
PMC9812014
Another research team isolated Homonojirimycin (HNJ), an alkaloid from the Commelina communis L., and tested its antiviral efficacy on the IAV/PR/8/34 (H1N1) strain.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10748106
For those Genipin derivatives we also modified the substituent of C10, represented by R1.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "those", "Genipin", "derivatives", "we", "also", "mod...
PMC10723784
In the present study, CBD and CBG induced time‐ and concentration‐dependent cytotoxicity in cisplatin‐sensitive and ‐resistance ovarian carcinoma cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "O" ], "tokens": [ "In", "t...
PMC11775197
Although the role of PPARs in CRC is not fully understood, developing novel therapies targeting PPARs has become a new trend.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Although", "...
PMC4270159
e. Run the sample at 175 V for 25 min.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "e.", "Run", "the", "sample", "at", "175", "V", "for", "25", "min", "." ] } ]
PMC11611077
Lane 4: multitope recombinant protein including 6×His (internal and C-terminal) with a molecular weight of 74 kDa.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Lane", "4", ...
PMC9599726
The study was approved by the Institutional Medical Ethics Committees of Erasmus Hospital and Faculty of Medicine, Université Libre de Bruxelles (reference number P2016/316); the Ethical Committee of Institut Jules Bordet (reference number CE 2964), Brussels, Belgium; and the Medical Ethics Committee, UZ Leuven, Leuven, Belgium (reference number S66100) for their respective human materials.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6337547
Currently, flavonoids are isolated from natural plants, such as Salvia plebeia R. Br.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Currently", ",", "flavonoids", "are", "isolated", "from", "...
PMC10366908
Therefore, sensitive mAbs against mouse EGFR (mEGFR) should be established.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "sensitive", "mAbs", "against", "mouse", "EGFR", "(", ...
PMC11697065
All vectors were constructed based on standard cloning methods.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "vectors", "were", "constructed", "based", "on", "standard", "cloning", "methods", "." ] } ]
PMC11075223
In China, Cimicifugae Rhizoma is stipulated as a food supplement and the fresh products have the efficacy of detoxification, detumescence and relieving throat disorder .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9429973
Under these conditions, a decrease in the number of blast cells, the concentration of cytokines TNF and TGF β1 in the plasma and the achievement of remission were observed.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9964635
Element analysis: C, 70.85; H, 9.16; N, 12.72% (Figures S2 and S7).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Element", "analysis", ...
PMC7081114
Our results provide evidence that KIF21B may be considered as a novel prognostic biomarker and a new therapeutic molecular target for HCC.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Our", "resul...
PMC11438317
The insert shows the IB of the Vav and LYP proteins expressed. *
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "insert", "shows", "the", "IB", "of", "the", "Vav", "and", ...
PMC11515150
5D and 12 C competed for binding to the epitope of CD5 molecule on the Jurkat cell membrane, as determined with binding competition studies by flow cytometry.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11569208
Signaling pathway topology analyses were performed using Graphite and CliPPER (Department of Biology, University of Padova, Italy).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Signaling", "pathway", ...
PMC9516447
The superscript indicates the KRAS mutation for each cell line.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "superscript", "indicates", "the", "KRAS", "mutation", "for", "each", "cell", "line", ...
PMC5811757
To knockdown ABCB1 gene, 3 sgRNAs targeting human ABCB1 gene were selected.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "knockdown", "ABCB1", "gene", ",", "3", "sgRNAs", "targeting", "...
PMC11347429
The minor allele frequency ranged from 0 to 0.5 ( Supplementary Figure S2B ).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "minor", "allele", "frequency", "ranged", "from", "0", "to...
PMC9429973
along with T-ASO (5mg/kg) via intraperitoneal (i.p.)
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "along", "with", "T-ASO", "(", "5mg/kg", ")", "via", "intraperitoneal", "(", "i.p", ...
PMC10024132
The E/T ratio of 10 was used in all experiments for consistency with our previous studies unless otherwise noted.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "E/T", "ratio", "of", ...
PMC11116779
One of the hallmarks of the senescent phenotype, CDKN1A, increased its expression up to 30% following cell exposure to 500 μg/mL PS-NPs (Figure 4B).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11687167
The 22-kb human PCSK9 gene is located on chromosome 1p32 and consists of 12 exons and 11 introns.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "22-kb", "human", "PCSK9", "gene...
PMC11206502
Briefly, for the measurement of basal metabolic rates, measurements of OCR and ECAR were taken at the starting assay conditions.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Briefly", ",...
PMC11657744
Specifically, CEP89 and FBF1 contribute to ciliary disassembly by regulating Aurora A kinase stability and basal body localization AurA is known to localize to the basal body, where it activates HDAC6 to promote ciliary tubulin deacetylation .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11740907
In Figure 8B, the group that received P5W30-BW-SLNs therapy observed a more significant reduction in tumor weight % compared to the group which obtained pure P5W30 alone, on the 10th day after administration.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7053076
The best known transporters that were shown to reduce the cellular uptake of anticancer drugs, including 5-FU, are P-glycoprotein (ABCB1), multidrug resistance associate protein 1 (ABCC1) and breast cancer resistance protein (ABCG2) [14–20].
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11806818
B The synthesis process of MoS2-MIL-101(Fe) and schematic diagram of exosome detection mechanism of the proposed method.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "B", "The", "synthesis", "process", "of...
PMC10197932
However, deep analysis needed regarding the viability and functionality of other lymphocyte subsets like CD4, CD19, Tregs, or Neutrophile granulocytes.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC7305184
Looking overall at our result only in two data points statistical difference between CTRL and EP group and one between CTRL + EP and EP group were detected, which, however, disappeared with the next generations and with the repetition of the experiment.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9545474
The percentages of cells with depolarised mitochondrial membrane potential were assessed by flow cytometry after staining with JC‐10.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "percentages", "of", "cells", "w...
PMC11496728
The incubation product was transformed into DH5α competent cells, and the shaking bacteria were sequenced after expansion culture.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "incubation", "product", "w...
PMC10890307
A metabolic symbiosis or parasitism relationship may also occur among cancer-associated fibroblasts (CAFs) and tumor cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "metabolic", "symbiosis", "or", "p...
PMC11612626
E.G7-Ova cells were pretreated with compounds (1 μmol/L), after which the cells were washed and co-cultured with the H-2Kb–restricted B3Z T cells genetically engineered to express a TCR that specifically recognizes the SIINFEKL–H2Kb complex.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11033779
OBJECTIVES/GOALS: The molecular basis of increased risk of triple negative breast cancer in non-Hispanic Black women represents a critical knowledge gap that this research is designed to address; successful completion of this work could lead to better prevention, earlier stage diagnoses, and possible discovery of novel therapeutic strategies for this population.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
J. Wang, B. Jiang, J. Li, L. Liu, X. Du, H. Jiang, J. Hu, M. Yuan, T. Sakatani, T. Kadokura, M. Takeuchi, S. Izuka, L. Girshova, J. Tan, S. Bondarenko, L. L. L. Wong, A. Khuhapinant, E. Martynova, N. Hasabou, R. Tiu State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin; Department of Hematology, Peking University International Hospital; Department of Hematology, Peking Union Medical College Hospital, Beijing; Department of Hematology, Shanghai Tongren Hospital, Shanghai; Department of Hematology, Guangdong Provincial People’s Hospital, Guangzhou; Department of Hematology, Peking University Peoples Hospital, Beijing; Fujian Institute of Hematology, Fujian Medical University Union Hospital, Fuzhou, Fujian; Astellas Pharma, Inc., Beijing, China; Astellas Pharma, Inc., Tokyo, Japan; Almazov National Medical Research Centre, St. Petersburg, Russia; Department of Medicine, Faculty of Medicine and Health Sciences, Universiti Malaysia Sarawak, Sarawak, Malaysia; Department of Hematology, Ampang Hospital, Selangor, Malaysia; Clinical Research Institution of Pediatric Hematology and Transplantation under the Name of Raisa Gorbacheva, State Medical University, St. Petersburg, Russia; Hematology Unit, Queen Elizabeth Hospital, Kota Kinabalu, Sabah, Malaysia; Division of Hematology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand; Krasnoyarsk Regional Clinical Hospital, Krai, Russia; Astellas Pharma, Inc., Northbrook, United States of America Background: Due to poor prognosis, treatment options for patients (pts) with relapsed/refractory to therapy (R/R) FLT3-mutated (FLT3) acute myeloid leukemia (AML) are needed globally.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11078693
Position the top part of the magnetic chamber on top of the cover glass, so that the magnet can press the o-ring against the glass, and gently rotate to ensure a proper seal.h.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9243326
Integrating the results of these two methods, a total of 1,277 ncRNA transcripts were predicted, accounting for only 4.85% of the total data.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11534035
Similarly to the A431 cell line, the knockdown treatment of CAL39 cells led to a significant reduction in colony size (Figure 6F) compared to control cells (KD=38.35±1.852 px vs. control=46.80±2.790 px; p<0.05).
[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC8414691
Three independent experiments were performed. *
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Three", "independent", "experiments", "were", "performed", ".", "*" ] } ]
PMC5025404
According to the literature, the expression of the LC in excess has a positive effect on the quality of the mAbs, and the ratio of LC:HC expression can affect mAb qualities such as glycosylation and aggregation (Schlatter et al. 2005; Lee et al. 2009).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9111184
Moreover, it has been shown that in the intestine, activation of LXR enhances fecal sterol excretion via upregulation of the transporter heterodimer ABCG5/G8 (Hiebl et al., 2018).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
In 11 patients, positive immunomagnetic selection of CD138+ bone marrow cells was performed using a monoclonal antibody to CD138 (Miltenyi Biotec, Germany).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6181431
63 to 69% of all somatic mutations were not detectable across every tumor region of RCC when multiple samples were analyzed , similar to our findings that 46% of somatic mutations were not seen in both of our paired samples for these 6 patients (S2 Table).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11470381
Figure 2.Preprocessing of 2D time-lapse stack before ROI detection.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Figure", "2.Preprocessing", "of", "2D", "time-lapse", "stack", "before", "ROI", "detection", "." ] } ...
PMC11703992
The single-cell data GSE157007 and GSE198891 were profiled using GPL24676 platform .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "single-cell", "data", "GSE157007", "and", "GSE198891", "were", "profiled", "using", ...
PMC9429973
All these events were grade 1.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "these", "events", "were", "grade", "1", "." ] } ]
PMC11093197
Most importantly, overexpressed H‐RAS significantly downregulated p27 levels in MCF10A cells (Figure 4E).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Most", "importantly", ",", "overexpressed", "H‐RAS"...
PMC9918897
There are several possible reasons for the phenomenon observed.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "There", "are", "several", "possible", "reasons", "for", "the", "phenomenon", "observed", "." ] } ]
PMC9429973
However, there were no clear differences between both groups in the risk of transformation to AML.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "there", "were", "no", "clea...
PMC10507284
Currently, effective treatment measures for STS patients with advanced, metastatic, and recurrent are still limited, apart from chemotherapy, antiangiogenic drugs, and a few specific targeted drugs.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11093197
Dormancy is a cellular state where cells exit the cell cycle and remain undivided for prolonged periods yet retaining the ability to re‐enter the cell cycle.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC10976516
Increased tumor T cell retention and accumulation in tumor and TME.Sostoa et al.Freedman et al.Recombinant adenovirus KGHV500, expressing anti-p21Ras scFvIntravenousCIK cellsCIKs loaded with KGHV500 were intravenously injected into an A549 tumor xenotransplant model leading to significantly increased tumor regression.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11188874
We identified 30 neoantigens on multiple myeloma cells, generated through either mutation or PTM, that were upregulated by treatment with tubastatin-A or ACY-738 (Supplementary Table S5A).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9512971
All tests were two-sided with a significance level of 5%.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "tests", "were", "two-sided", "with", "a", "significance", "level", "of", "5", ...
PMC9429973
Aims: Our study aims to characterize how AZA treatment shapes the identity of MAPs presented by AML cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ":", "Our", "study", ...
PMC11700340
significant at (P<0.05) Comparison of Linagliptin and Vincristine Growth Inhibition at 24 hours , standard error; , least significant difference.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "signifi...
PMC11413393
d Volcano plots of Alternative Splice Events (ASEs) significantly (FDR < 0.01) downregulated (red, left, ΔPSI < −0.1) or upregulated (red, right, ΔPSI > 0.1) following 3 days of 5 μM MS023 treatment or 4 days of doxycycline induction.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...