OTAR3088/BioData-CellLine_annotated · Datasets at Hugging Face

PMCID string	Sentences string	ner list
PMC11806182	These effects are consistent with progesterone’s known ability to inhibit proliferation and promote metabolic stability in cancer cells .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "effects", "are", "consis...
PMC11472639	We also characterised the effects of a single bout of cycling 15% above anaerobic threshold on T-cell subsets, the summary data and statistical results of which can be seen in Table 7.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9479186	In addition to providing energy, mitochondria also play an important role in regulating the cell cycle, cell apoptosis, Ca homoeostasis, and Fe–S cluster biogenesis (5, 6).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11765988	M1 (“killer”) macrophages, the first line of defense against intracellular pathogens, induce Th1 CD4+ response and complement-mediated phagocytosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11730320	This variant could not be detected by clinical genotyping or genome hybridization arrays.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "variant", "could", "not", "be", "detected", "by", "clinical", ...
PMC10958426	While detected UMIs and detected genes of other cell types in tumor tissues were not significantly different from their counterparts in normal tissues (Figs. S1F and G).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	We have detected atypical inserts in 16 out of 78 cases (20.5%), which is more than reported in the literature.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973	Exome analysis of both families together with one family harboring PAX5 p.Gly183Ser previously reported by Auer et al., (Leukemia, 2014) yielded no additional common germline variants that could explain the incomplete penetrance in the observed leukemia development.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11657695	Overall, these results clearly demonstrate the presence of Kv1.2 currents in A-673 ES cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O" ], "tokens": [ "Overall", ",", "these", "results", "clearly", "demonstra...
PMC9429973	Methods: We used formalin-fixed paraffin-embedded (FFPE) lymph node samples of 37 patients with newly diagnosed NSCHL who were treated at the clinic of KRIHBT in the period from 2006 to 2018.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11638255	Notably, these animals did not exhibit any signs of relapse following cessation of treatment up to the experimental endpoint of 90 days.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Notably...
PMC11759751	Data presented as mean ± SD with three replicates.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "presented", "as", "mean", "±", "SD", "with", "three", "replicates", "." ] } ]
PMC11515150	no significance) 12 C CAR-NK cells exhibit superior antitumor activity in vivo. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "no", "significance", ")", "12", "C", "CAR-NK", "cells", "exhibit...
PMC10890055	The materials were prepared similarly as in .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "materials", "were", "prepared", "similarly", "as", "in", "." ] } ]
PMC9429973	3 patients reduced the dose as a practical alternative for fear of discontinuation; 2 patients discontinued, but after relapse they remained with the minimum dose to maintain MMR; the rest of the patient reduced doses because of intolerance.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11701801	The sample size (n) is indicated in the figure legends and represents the number of biological or technical replicates.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "sample", "...
PMC9429973	In secondary venetoclax resistant cases displaying wild type BCL2, further molecular screening methods are required to reveal alternative genetic or non-genetic reasons for disease progression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC10761571	The BAX is a pro-apoptotic protein that is involved in activating of the intrinsic apoptosis through the increase of mitochondrial outer membrane permeabilization, while BCL2 is a BAX inhibitor protein .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10545062	Urine output represented as cumulative urine output over study time (mL/kg).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Urine", "output", "represented", "as", "cumulative", "urine", "output", "ov...
PMC10976516	The combination was tolerable, although associated with increased rates of neutropenic fever.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "combination", "was", "tolerable", ",", "although", "associated", "wi...
PMC11695546	This can significantly hinder an individual's capacity to perform everyday tasks (Tomášková et al. 2016).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "can", "significantly", "hinder", ...
PMC11343332	We observed that pycnogenol treatment significantly inhibited VEGF-A/FGF-2 gene expression in breast cancer cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "observed", "that", "pycnogenol", "treatment", "significantly", "...
PMC11224206	Deriving from classical works from Van’t Hoff and Arrhenius at the turn of the last century, it has long been known that the rate of a chemical reaction is intrinsically dependent on temperature.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11597167	Gallic acid (3,4,5-trihydroxybenzoic acid) is a hydroxybenzoic derivative of non-flavonoids classified among polyphenols .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Gallic", "acid", "(", "3,4,5-trihydroxybenzoic", "acid", ")", ...
PMC11594588	CF-LVADs, using a high-speed rotor to suck blood from the left ventricle and pump it through the graft to the aorta, cause nonphysiologically shear stresses .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	A trend toward better correlation of ALC with OS was observed in patients who received “3 + 7-based” regimen (30,8%;) versus those who were treated with “fludarabine-based” regimen (69,1%;).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8073654	Subsequently, Matsuda et al. reported the isolation and identification of eight new compounds, cassumunols A‒H (31‒38).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Subsequently", ",", "Matsuda...
PMC11291490	Data were presented as means ± s.d. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "were", "presented", "as", "means", "±", "s.d", ".", "(" ] } ]
PMC11521786	We used MitC, as a positive control in these assays.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "used", "MitC", ",", "as", "a", "positive", "control", "in", "these", "ass...
PMC11766309	P < 0.05, P < 0.01, P < 0.001, ***P < 0.0001.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973	Image: Summary/Conclusion: Limitations of BM cytomorphology when facing an isolated thrombocytopenia were demonstrated here.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Image", ":", "Summary/Conclusion", ":", "Limitations", ...
PMC6600253	Senescence can also be triggered by the activation of oncogenes (oncogene-induced senescence (OIS)) and the loss of tumor suppressor genes (TSGs), as discussed in detail in the following section.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9581083	This substance is also used to flavor foods and beverages (El-Saber Batiha et al., 2020).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "substance", "is", "also", "use...
PMC11754291	However, the exact mechanism underlying this phenomenon remains controversial.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "the", "exact", "mechanism", "underlying", "this", "phenomenon", "remains", "cont...
PMC10440586	Paired t-test, gray lines represent GSCs from the same patient. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Paired", "t-test", ",", "gray", "lines", "represent", "GSCs", "from", "the", ...
PMC9429973	The impact of bariatric surgery on CML treatment outcomes is largely unknown.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "impact", "of", "bariatric", "surgery", "on", "CML", "treatment", "outcome...
PMC11792766	Briefly, 50 µL of 2× LDH assay buffer was added to each well containing 50 µL of the collected exposure medium.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Briefly...
PMC11643491	Before the experiments, the cells were seeded and incubated to 70–80% confluence on a 10 cm dish.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Before", "the", "experiments", ",...
PMC11637284	P, pellet; SN, supernatant; FT, flow through; IP, eluate of immunoprecipitation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "P", ",", "pellet", ";", "SN", ",...
PMC6182045	To obtain a relative ranking of overall bNAb antigenicity, individual area under the curve (AUC) analyses were taken of individual gp120 binding curves to each of the 5 bNAbs, and the sum of these AUC values for each gp120 antigen was ranked.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11711663	The color scale represents the strength of the correlation, with blue indicating negative correlation, red indicating positive correlation, and white representing no correlation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11474209	The toxicity brought on by MC-LR is related to epigenetic alterations.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "toxicity", "brought", "on", "by", "MC-LR", "is", "related", "to", "epigenetic"...
PMC9429973	Results: From August 2020 to January 2022, 10 patients were enrolled, and the cut-off date was February 25, 2022.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results...
PMC9429973	At the same time, our data are valuable as indicate high probability of parallell manifestation (for one reason or another) of COVID-19 and latent herpesvirus infection reactivation in NHL patients.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC2118063	Input DNA (1:400) was used as a control.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Input", "DNA", "(", "1:400", ")", "was", "used", "as", "a", "control", "." ] } ]
PMC9429973	Engraftment defined according to EBMT criteria.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Engraftment", "defined", "according", "to", "EBMT", "criteria", "." ] } ]
PMC9065483	RNA was extracted from cell lysates at 8 and 24 hpi and probed for VSV-M and VSV-N gene expression by qPCR (n = 4, mean ± SD; ∗p < 0.05, ∗∗p < 0.01 by one-way ANOVA, n.s.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11755624	Under pathological conditions, the expression of lncRNAs is frequently dysregulated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Under", "pathological", "conditions", ",", "the", "expression", "of", "lncRNAs", "is", ...
PMC11055323	a Schematic illustration for SS18-SSX onco-fusion in synovial sarcoma.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "a", "Schematic", "illustration", "for", "SS18-SSX", "onco-fusion", "in", "synovial", "sarcoma", "." ] ...
PMC9429973	In addition, SRE binding factors SREBF1 and SREBF2 were overexpressed under EZH2i.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "addition", ",", "SRE", "binding", "factors", "SREBF1", "and", "...
PMC10125312	The approaches selected should look at different markers of viability: metabolic activity (e.g., MTT, XTT), membrane permeability (e.g., Trypan Blue or propidium iodide staining), enzymatic activity (e.g., LDH), or DNA synthesis/replication.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5600151	They referred to them as a cascade of molecules.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "They", "referred", "to", "them", "as", "a", "cascade", "of", "molecules", "." ] } ]
PMC11637284	Two of these regions corresponded to TAC60 domains that are exposed to the cytosol.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Two", "of", "these", "regions", "corresponded", "to", "TAC60", "...
PMC6892818	Apoptosis signal-regulating kinase 1 (ASK1) MAP3K acts upstream of p38/JNK and its activation is ROS-mediated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Apoptosis", "signal-regulating", "kinase", "...
PMC11574271	RON (565692) was obtained from BD.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "RON", "(", "565692", ")", "was", "obtained", "from", "BD", "." ] } ]
PMC10761571	According to the SEM (Fig. 3a and d) and TEM (Fig. 3c and b) images the Fe3O4@Glu-Gingerol particles were spherical and were in a size range of 42–67 nm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11240571	sc-9148), CD63 (Santa Cruz Biotechnology, cat.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "sc-9148", ")", ",", "CD63", "(", "Santa", "Cruz", "Biotechnology", ",", "cat", "." ] ...
PMC11290772	Cell viability of ovarian primary tumor cells or cell lines was assessed using the Cell Counting Kit-8 (CCK-8, C0039, Beyotime, Shanghai, CN) according to the instructions provided in the data sheet.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5417661	Cells treated with NOV202 (3.0 and 50 nM), or reference drug paclitaxel (5.0 and 50 nM), vinblastine (5.0 and 50 nM) or epothilone (5.0 and 50 nM), were filmed in three replicates with IncuCyte live cell imager (Essen BioScience) using 1 h interval for a total of 72 h after adding the compounds on cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11653533	Hence, it was reported that quercetin and naringenin exhibited stronger antibacterial activity against both bacteria, where cinnamic acid and lactose showed potent activity against the P. aeruginosa and moderate activity against the B. cereus, however caffeic acid and stigmasterol yield weak activity against the two species of those bacteria, in addition, only caffeic acid manifested powerful cytotoxic potency with IC50 value of 25 mg/mL (Almahy et al., 2003).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11310713	P < 0.05, P < 0.01, and P < 0.001 versus Ovary-Intact. *	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "P", "<", "0.05", ",", "P", "<", "0.01", ",", "a...
PMC9712534	The mobile fractions were estimated to be 0.86 ± 0.06 (DMSO) and 0.20 ± 0.03 (ICRF).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "mobile", "fractions",...
PMC11435360	Importantly, the pro-apoptotic and anti-neovascularization effects of gemcitabine were enhanced by propargylglycine co-administration.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Importantly", ",", "the", "pro-apoptotic", "and", "anti-neovascularization",...
PMC11787355	d Percentage of surface activation marker-positive, CD137, cells in CD8 TCR-T cells upon 24 h coculture with target cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "d", "Percentage", ...
PMC11507371	After the final washing step, 30 μL of each cell suspension was loaded into the chambers of an NC-Slide A2TM (ChemoMetec A/S, Steen Søndergaard, Denmark).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11209164	Following this incubation period, the culture medium was removed and replaced with an overlay.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Following", "this", "incubation", "period", ",", "the", "cu...
PMC9429973	P. L. Zinzani, M. Özcan, K. Sapunarova, W. Jurczak, A. Hamed, K. Bouabdallah, G. Saydam, K. Geissler, Á. Szomor, M. Lazaroiu, A. Salar, A. Tempescul, M. Nalcaci, L. Gercheva, M. Egyed, P. Panayiotidis, L. Mongay Soler, A. Cao, C. Phelps, B. H Childs, M. J Matasar IRCCS Azienda Ospedaliero-Universitaria di Bologna, Istituto di Ematologia “Seragnoli”; Dipartimento di Medicina Specialistica, Diagnostica e Sperintale, Universita di Bologna, Bologna, Italy; Ankara University School of Medicine, Ankara, Turkey; Medical University, Plovdiv, Bulgaria; Maria Skłodowska Curie National Research Institute of Oncology, Krakow, Poland; Petz Aladár Megyei Oktató Kórház, Gyor, Hungary; Hematology and Cellular Therapy Department, University Hospital of Bordeaux, Bordeaux, France; Ege Üniversitesi Tip Fakültesi, Izmir, Turkey; Sigmund Freud University, Vienna, Austria; Pécsi Tudományegyetem Klinikai Központ, Pécs, Hungary; S.C. Policlinica de Diagnostic Rapid S.A., Brasov, Romania; Hospital del Mar, Barcelona, Spain; Hôpital Morvan - Brest, Brest, France; Istanbul Universitesi İstanbul Tip Fakultesi, Istanbul, Turkey; MHAT Sveta Marina EAD, Varna, Bulgaria; Somogy Megyei Kaposi Mor Oktato Korhaz, Kaposvar, Hungary; First Department of Propaedeutic Internal Medicine, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece; Bayer HealthCare Pharmaceuticals, Inc., Whippany, NJ; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, United States of America Background: The Phase III CHRONOS-3 trial of copanlisib plus rituximab (C+R) vs placebo plus rituximab (P+R) in patients (pts) with indolent NHL (iNHL) showed a significant improvement in progression-free survival (PFS; hazard ratio [HR] 0.52; Matasar et al. Lancet Oncol 2021).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Baicalin treatments decreased MMP9 protein levels in small intestinal tissues detected by IHC (Fig 5C, D).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Baicalin", "treatments", "decreased", ...
PMC8427838	Coomassie Blue stain of GST, GST-FERM and GST-C-ERMAD in Whole Cell Lysate (WCL) or pulled-down proteins.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Coomassie", "Blue", "stain", "of"...
PMC11770746	The mice were placed on a grid and allowed to accustom to the new environment for at least half an hour.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "mice", "we...
PMC11747467	This study was conducted in accordance with the Animals in Research: Reporting In Vivo Experiments (ARRIVE) guidelines (18).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", ...
PMC8992508	Results of the theoretical models were compared with the experimental results.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", "of", "the", "theoretical", "models", "were", "compared", "with", "the", "e...
PMC11643491	Rather than focusing on the extent of cell internalization with particle elongation level, we specifically explored whether particle elongation might provide specificity towards highly aggressive and deformable cancer cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11734514	PTEN protein expression in A549 cells treated with C. aerizusa extract increased at 12 hours, coinciding with Akt suppression (Figure 3A–C).	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8097906	Metabolites were identified in comparison to the Golm Metabolome Database or putatively annotated as described previously .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Metabolites", "were", "identified", "in", "comparison", ...
PMC10654497	Student’s t-test was used for comparisons between two groups.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Student", "’s", "t-test", "was", "used", "for", "comparisons", "between", "two", "groups", ...
PMC6461034	Overview of an MS‐based phosphoproteomics experiment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Overview", "of", "an", "MS‐based", "phosphoproteomics", "experiment", "." ] } ]
PMC11487720	TRAPPC6A can be a tour guide for leading the TRADD/TRAF2/WWOX/p53 complex to undergo nuclear translocation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "TRAPPC6A", "can", "be", "a", "tour", "guide", "for", ...
PMC11021472	Sequence analysis of the exogenous circZDHHC11 including the BSJ region, confirmed proper formation of circZDHHC11 with a correct ligation of the 5’ to the 3’ ends (Supplemental Fig. 6A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11711127	Involution of thymus has been described as one of the causes of immunosenescence.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Involution", "of", "thymus", "has", "been", "described", "as", "one", ...
PMC9844987	TFs follow the same order as in panel A. (A) Average contribution (SHAP values) of CpG content and each of the 124 TFs identified as important for predicting promoter variability.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9878278	SC and A549 (lung epithelial cell-derived cell line routinely used to study ZIKV antiviral immunity) were treated with two doses of IFN-β before infection and we observed a significant reduction of ZIKV titers in a dose-dependent manner that was comparable in both cell types (Figure 1F).	[ { "tags": [ "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11612315	A cutoff value of 20 s was used to prevent tissue damage.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "cutoff", "value", "of", "20", "s", "was", "used", "to", "prevent", ...
PMC11706776	Brown rectangles correspond to transcribed and translated exons, while the salmon rectangles correspond to transcribed but not translated exons.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Brown", "rectangles", "corre...
PMC5600151	Third, an abundant amount of tertiary amines in dendrimer structures facilitates the endosomal escape of nucleic acid molecules through a “proton sponge” effect .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11666785	In another application, SMLM is realized using a Bessel beam for 3D imaging of nucleoporin Nup153 expressed in HeLa cell nucleus.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O" ], "tokens": [ "In", ...
PMC11774112	In vitro antitumor effect of Co-PHRD. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "vitro", "antitumor", "effect", "of", "Co-PHRD", ".", "(" ] } ]
PMC11593084	Therefore, PDPN in tumors and CAFs has been recognized as a useful diagnostic marker and an attractive target for tumor therapy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ...
PMC8984067	For anti-EpCAM-UCNPs-Ce6, the biosafety, targeting effect, and PDT effect exposed under near-infrared (NIR) laser (980 nm) were evaluated using human liver cancer cells (BEL-7404).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	At a median follow-up of 20.8 (95% CI: 17.4-23.7) months, the 12-month PFS rate (primary endpoint) was 48.9% (22/45, 90% CI: 35.9−62.0) with 11 events of PD/death, 8 dropouts, and 4 missing response data, which exceeded the threshold of 36% but did not meet significance (p=0.0518).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11786704	Acute mice skin wound models were established in a similar way to the chronic wound model, except that the diabetic mice were replaced with normal mice.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11746942	Notably, the activation of STAT3 was significantly reduced by keratinocyte S1PR3 knockdown, compared with that in IMQ-induced mice (Fig. 3G), which was further confirmed by western blot analysis (Fig. 3H).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11643361	Cobalt and vanadium scorpionate complexes, with a dipolar tridentate N,N-bis(3,5-dimethylpyrazol-1-ylmethyl)amine ligand (63–65, Figure 7), have also been studied .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9111184	The permeability of hydroxycinnamic acid derivatives and EZ in presence of cholesterol was studied by using the Caco-2 cell line differentiated as a monolayer, in a Transwell system.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10809689	RP-HPLC was done on a C18 column (150 * 4.6 mm, 5 μm), using Mobile-phase A (1 g K2PO4 + 0.5 g KH2PO4 in 500 mL distilled water), and B (100 mL distilled water, 150 mL acetonitrile, and 300 mL isopropanol) with linear gradient from 10–100% B at a flow rate of 1.2 mL/min in 35 min The results of the RP-HPLC technique for the determination of glutamate (Glu) metabolite in samples have revealed that the concentration of glutamate decreased in the HL-60 cell line after 72 h of treatment with Gal-9 compared to the PMA and control group, even though this reduction was not significant statistically (p = 0.37) (Fig. 7).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8540611	They were preincubated for 24 h and a further 72 h after adding complexes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "They", "were", "preincubated", "for", "24", "h", "and", "a", ...
PMC11750165	Products from heteroduplex analysis were electrophoresed on 2% agarose gels (Invitrogen).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Products", "from", "heteroduplex", "analysis", "were", "electrophoresed", ...
PMC6889484	Co-expression of Vif2 resulted in lower hypermutation frequencies for all three vectors, although a high frequency of hypermutation was still observed for A3G(DK) proviral genomes (40/60 clones).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Secondary endpoints were median survival time (MST) and safety.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Secondary", "endpoints", "were", "median", "survival", "time", "(", "MST", ")", "and"...
PMC11588085	Therefore, XIST KD may protect OVCAR3-KRAB cells from hypoxia-induced cell death probably by increasing the CSC population.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "XIST", "KD", ...

PMC11806182

These effects are consistent with progesterone’s known ability to inhibit proliferation and promote metabolic stability in cancer cells .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "effects", "are", "consis...

PMC11472639

We also characterised the effects of a single bout of cycling 15% above anaerobic threshold on T-cell subsets, the summary data and statistical results of which can be seen in Table 7.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9479186

In addition to providing energy, mitochondria also play an important role in regulating the cell cycle, cell apoptosis, Ca homoeostasis, and Fe–S cluster biogenesis (5, 6).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11765988

M1 (“killer”) macrophages, the first line of defense against intracellular pathogens, induce Th1 CD4+ response and complement-mediated phagocytosis.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...

PMC11730320

This variant could not be detected by clinical genotyping or genome hybridization arrays.

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PMC10958426

While detected UMIs and detected genes of other cell types in tumor tissues were not significantly different from their counterparts in normal tissues (Figs. S1F and G).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

We have detected atypical inserts in 16 out of 78 cases (20.5%), which is more than reported in the literature.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC9429973

Exome analysis of both families together with one family harboring PAX5 p.Gly183Ser previously reported by Auer et al., (Leukemia, 2014) yielded no additional common germline variants that could explain the incomplete penetrance in the observed leukemia development.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11657695

Overall, these results clearly demonstrate the presence of Kv1.2 currents in A-673 ES cells.

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PMC9429973

Methods: We used formalin-fixed paraffin-embedded (FFPE) lymph node samples of 37 patients with newly diagnosed NSCHL who were treated at the clinic of KRIHBT in the period from 2006 to 2018.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11638255

Notably, these animals did not exhibit any signs of relapse following cessation of treatment up to the experimental endpoint of 90 days.

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PMC11759751

Data presented as mean ± SD with three replicates.

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PMC11515150

no significance) 12 C CAR-NK cells exhibit superior antitumor activity in vivo. (

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PMC10890055

The materials were prepared similarly as in .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "materials", "were", "prepared", "similarly", "as", "in", "." ] } ]

PMC9429973

3 patients reduced the dose as a practical alternative for fear of discontinuation; 2 patients discontinued, but after relapse they remained with the minimum dose to maintain MMR; the rest of the patient reduced doses because of intolerance.

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PMC11701801

The sample size (n) is indicated in the figure legends and represents the number of biological or technical replicates.

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PMC9429973

In secondary venetoclax resistant cases displaying wild type BCL2, further molecular screening methods are required to reveal alternative genetic or non-genetic reasons for disease progression.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...

PMC10761571

The BAX is a pro-apoptotic protein that is involved in activating of the intrinsic apoptosis through the increase of mitochondrial outer membrane permeabilization, while BCL2 is a BAX inhibitor protein .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10545062

Urine output represented as cumulative urine output over study time (mL/kg).

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PMC10976516

The combination was tolerable, although associated with increased rates of neutropenic fever.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "combination", "was", "tolerable", ",", "although", "associated", "wi...

PMC11695546

This can significantly hinder an individual's capacity to perform everyday tasks (Tomášková et al. 2016).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "can", "significantly", "hinder", ...

PMC11343332

We observed that pycnogenol treatment significantly inhibited VEGF-A/FGF-2 gene expression in breast cancer cells.

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PMC11224206

Deriving from classical works from Van’t Hoff and Arrhenius at the turn of the last century, it has long been known that the rate of a chemical reaction is intrinsically dependent on temperature.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11597167

Gallic acid (3,4,5-trihydroxybenzoic acid) is a hydroxybenzoic derivative of non-flavonoids classified among polyphenols .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Gallic", "acid", "(", "3,4,5-trihydroxybenzoic", "acid", ")", ...

PMC11594588

CF-LVADs, using a high-speed rotor to suck blood from the left ventricle and pump it through the graft to the aorta, cause nonphysiologically shear stresses .

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PMC9429973

A trend toward better correlation of ALC with OS was observed in patients who received “3 + 7-based” regimen (30,8%;) versus those who were treated with “fludarabine-based” regimen (69,1%;).

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PMC8073654

Subsequently, Matsuda et al. reported the isolation and identification of eight new compounds, cassumunols A‒H (31‒38).

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PMC11291490

Data were presented as means ± s.d. (

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PMC11521786

We used MitC, as a positive control in these assays.

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PMC11766309

P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.

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PMC9429973

Image: Summary/Conclusion: Limitations of BM cytomorphology when facing an isolated thrombocytopenia were demonstrated here.

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PMC6600253

Senescence can also be triggered by the activation of oncogenes (oncogene-induced senescence (OIS)) and the loss of tumor suppressor genes (TSGs), as discussed in detail in the following section.

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PMC9581083

This substance is also used to flavor foods and beverages (El-Saber Batiha et al., 2020).

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PMC11754291

However, the exact mechanism underlying this phenomenon remains controversial.

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PMC10440586

Paired t-test, gray lines represent GSCs from the same patient. (

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PMC9429973

The impact of bariatric surgery on CML treatment outcomes is largely unknown.

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PMC11792766

Briefly, 50 µL of 2× LDH assay buffer was added to each well containing 50 µL of the collected exposure medium.

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PMC11643491

Before the experiments, the cells were seeded and incubated to 70–80% confluence on a 10 cm dish.

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PMC11637284

P, pellet; SN, supernatant; FT, flow through; IP, eluate of immunoprecipitation.

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PMC6182045

To obtain a relative ranking of overall bNAb antigenicity, individual area under the curve (AUC) analyses were taken of individual gp120 binding curves to each of the 5 bNAbs, and the sum of these AUC values for each gp120 antigen was ranked.

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PMC11711663

The color scale represents the strength of the correlation, with blue indicating negative correlation, red indicating positive correlation, and white representing no correlation.

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PMC11474209

The toxicity brought on by MC-LR is related to epigenetic alterations.

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PMC9429973

Results: From August 2020 to January 2022, 10 patients were enrolled, and the cut-off date was February 25, 2022.

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PMC9429973

At the same time, our data are valuable as indicate high probability of parallell manifestation (for one reason or another) of COVID-19 and latent herpesvirus infection reactivation in NHL patients.

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PMC2118063

Input DNA (1:400) was used as a control.

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PMC9429973

Engraftment defined according to EBMT criteria.

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PMC9065483

RNA was extracted from cell lysates at 8 and 24 hpi and probed for VSV-M and VSV-N gene expression by qPCR (n = 4, mean ± SD; ∗p < 0.05, ∗∗p < 0.01 by one-way ANOVA, n.s.

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PMC11755624

Under pathological conditions, the expression of lncRNAs is frequently dysregulated.

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PMC11055323

a Schematic illustration for SS18-SSX onco-fusion in synovial sarcoma.

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PMC9429973

In addition, SRE binding factors SREBF1 and SREBF2 were overexpressed under EZH2i.

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PMC10125312

The approaches selected should look at different markers of viability: metabolic activity (e.g., MTT, XTT), membrane permeability (e.g., Trypan Blue or propidium iodide staining), enzymatic activity (e.g., LDH), or DNA synthesis/replication.

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PMC5600151

They referred to them as a cascade of molecules.

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PMC11637284

Two of these regions corresponded to TAC60 domains that are exposed to the cytosol.

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PMC6892818

Apoptosis signal-regulating kinase 1 (ASK1) MAP3K acts upstream of p38/JNK and its activation is ROS-mediated.

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PMC11574271

RON (565692) was obtained from BD.

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PMC10761571

According to the SEM (Fig. 3a and d) and TEM (Fig. 3c and b) images the Fe3O4@Glu-Gingerol particles were spherical and were in a size range of 42–67 nm.

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PMC11240571

sc-9148), CD63 (Santa Cruz Biotechnology, cat.

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PMC11290772

Cell viability of ovarian primary tumor cells or cell lines was assessed using the Cell Counting Kit-8 (CCK-8, C0039, Beyotime, Shanghai, CN) according to the instructions provided in the data sheet.

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PMC5417661

Cells treated with NOV202 (3.0 and 50 nM), or reference drug paclitaxel (5.0 and 50 nM), vinblastine (5.0 and 50 nM) or epothilone (5.0 and 50 nM), were filmed in three replicates with IncuCyte live cell imager (Essen BioScience) using 1 h interval for a total of 72 h after adding the compounds on cells.

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PMC11653533

Hence, it was reported that quercetin and naringenin exhibited stronger antibacterial activity against both bacteria, where cinnamic acid and lactose showed potent activity against the P. aeruginosa and moderate activity against the B. cereus, however caffeic acid and stigmasterol yield weak activity against the two species of those bacteria, in addition, only caffeic acid manifested powerful cytotoxic potency with IC50 value of 25 mg/mL (Almahy et al., 2003).

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PMC11310713

P < 0.05, P < 0.01, and P < 0.001 versus Ovary-Intact. *

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PMC9712534

The mobile fractions were estimated to be 0.86 ± 0.06 (DMSO) and 0.20 ± 0.03 (ICRF).

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PMC11435360

Importantly, the pro-apoptotic and anti-neovascularization effects of gemcitabine were enhanced by propargylglycine co-administration.

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PMC11787355

d Percentage of surface activation marker-positive, CD137, cells in CD8 TCR-T cells upon 24 h coculture with target cells.

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PMC11507371

After the final washing step, 30 μL of each cell suspension was loaded into the chambers of an NC-Slide A2TM (ChemoMetec A/S, Steen Søndergaard, Denmark).

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PMC11209164

Following this incubation period, the culture medium was removed and replaced with an overlay.

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PMC9429973

P. L. Zinzani, M. Özcan, K. Sapunarova, W. Jurczak, A. Hamed, K. Bouabdallah, G. Saydam, K. Geissler, Á. Szomor, M. Lazaroiu, A. Salar, A. Tempescul, M. Nalcaci, L. Gercheva, M. Egyed, P. Panayiotidis, L. Mongay Soler, A. Cao, C. Phelps, B. H Childs, M. J Matasar IRCCS Azienda Ospedaliero-Universitaria di Bologna, Istituto di Ematologia “Seragnoli”; Dipartimento di Medicina Specialistica, Diagnostica e Sperintale, Universita di Bologna, Bologna, Italy; Ankara University School of Medicine, Ankara, Turkey; Medical University, Plovdiv, Bulgaria; Maria Skłodowska Curie National Research Institute of Oncology, Krakow, Poland; Petz Aladár Megyei Oktató Kórház, Gyor, Hungary; Hematology and Cellular Therapy Department, University Hospital of Bordeaux, Bordeaux, France; Ege Üniversitesi Tip Fakültesi, Izmir, Turkey; Sigmund Freud University, Vienna, Austria; Pécsi Tudományegyetem Klinikai Központ, Pécs, Hungary; S.C. Policlinica de Diagnostic Rapid S.A., Brasov, Romania; Hospital del Mar, Barcelona, Spain; Hôpital Morvan - Brest, Brest, France; Istanbul Universitesi İstanbul Tip Fakultesi, Istanbul, Turkey; MHAT Sveta Marina EAD, Varna, Bulgaria; Somogy Megyei Kaposi Mor Oktato Korhaz, Kaposvar, Hungary; First Department of Propaedeutic Internal Medicine, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece; Bayer HealthCare Pharmaceuticals, Inc., Whippany, NJ; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, United States of America Background: The Phase III CHRONOS-3 trial of copanlisib plus rituximab (C+R) vs placebo plus rituximab (P+R) in patients (pts) with indolent NHL (iNHL) showed a significant improvement in progression-free survival (PFS; hazard ratio [HR] 0.52; Matasar et al. Lancet Oncol 2021).

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PMC9429973

Baicalin treatments decreased MMP9 protein levels in small intestinal tissues detected by IHC (Fig 5C, D).

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PMC8427838

Coomassie Blue stain of GST, GST-FERM and GST-C-ERMAD in Whole Cell Lysate (WCL) or pulled-down proteins.

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PMC11770746

The mice were placed on a grid and allowed to accustom to the new environment for at least half an hour.

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PMC11747467

This study was conducted in accordance with the Animals in Research: Reporting In Vivo Experiments (ARRIVE) guidelines (18).

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PMC8992508

Results of the theoretical models were compared with the experimental results.

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PMC11643491

Rather than focusing on the extent of cell internalization with particle elongation level, we specifically explored whether particle elongation might provide specificity towards highly aggressive and deformable cancer cells.

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PMC11734514

PTEN protein expression in A549 cells treated with C. aerizusa extract increased at 12 hours, coinciding with Akt suppression (Figure 3A–C).

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PMC8097906

Metabolites were identified in comparison to the Golm Metabolome Database or putatively annotated as described previously .

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PMC10654497

Student’s t-test was used for comparisons between two groups.

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PMC6461034

Overview of an MS‐based phosphoproteomics experiment.

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PMC11487720

TRAPPC6A can be a tour guide for leading the TRADD/TRAF2/WWOX/p53 complex to undergo nuclear translocation.

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PMC11021472

Sequence analysis of the exogenous circZDHHC11 including the BSJ region, confirmed proper formation of circZDHHC11 with a correct ligation of the 5’ to the 3’ ends (Supplemental Fig. 6A).

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PMC11711127

Involution of thymus has been described as one of the causes of immunosenescence.

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PMC9844987

TFs follow the same order as in panel A. (A) Average contribution (SHAP values) of CpG content and each of the 124 TFs identified as important for predicting promoter variability.

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PMC9878278

SC and A549 (lung epithelial cell-derived cell line routinely used to study ZIKV antiviral immunity) were treated with two doses of IFN-β before infection and we observed a significant reduction of ZIKV titers in a dose-dependent manner that was comparable in both cell types (Figure 1F).

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PMC11612315

A cutoff value of 20 s was used to prevent tissue damage.

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PMC11706776

Brown rectangles correspond to transcribed and translated exons, while the salmon rectangles correspond to transcribed but not translated exons.

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PMC5600151

Third, an abundant amount of tertiary amines in dendrimer structures facilitates the endosomal escape of nucleic acid molecules through a “proton sponge” effect .

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PMC11666785

In another application, SMLM is realized using a Bessel beam for 3D imaging of nucleoporin Nup153 expressed in HeLa cell nucleus.

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PMC11774112

In vitro antitumor effect of Co-PHRD. (

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PMC11593084

Therefore, PDPN in tumors and CAFs has been recognized as a useful diagnostic marker and an attractive target for tumor therapy.

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PMC8984067

For anti-EpCAM-UCNPs-Ce6, the biosafety, targeting effect, and PDT effect exposed under near-infrared (NIR) laser (980 nm) were evaluated using human liver cancer cells (BEL-7404).

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PMC9429973

At a median follow-up of 20.8 (95% CI: 17.4-23.7) months, the 12-month PFS rate (primary endpoint) was 48.9% (22/45, 90% CI: 35.9−62.0) with 11 events of PD/death, 8 dropouts, and 4 missing response data, which exceeded the threshold of 36% but did not meet significance (p=0.0518).

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PMC11786704

Acute mice skin wound models were established in a similar way to the chronic wound model, except that the diabetic mice were replaced with normal mice.

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PMC11746942

Notably, the activation of STAT3 was significantly reduced by keratinocyte S1PR3 knockdown, compared with that in IMQ-induced mice (Fig. 3G), which was further confirmed by western blot analysis (Fig. 3H).

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PMC11643361

Cobalt and vanadium scorpionate complexes, with a dipolar tridentate N,N-bis(3,5-dimethylpyrazol-1-ylmethyl)amine ligand (63–65, Figure 7), have also been studied .

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PMC9111184

The permeability of hydroxycinnamic acid derivatives and EZ in presence of cholesterol was studied by using the Caco-2 cell line differentiated as a monolayer, in a Transwell system.

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PMC10809689

RP-HPLC was done on a C18 column (150 * 4.6 mm, 5 μm), using Mobile-phase A (1 g K2PO4 + 0.5 g KH2PO4 in 500 mL distilled water), and B (100 mL distilled water, 150 mL acetonitrile, and 300 mL isopropanol) with linear gradient from 10–100% B at a flow rate of 1.2 mL/min in 35 min The results of the RP-HPLC technique for the determination of glutamate (Glu) metabolite in samples have revealed that the concentration of glutamate decreased in the HL-60 cell line after 72 h of treatment with Gal-9 compared to the PMA and control group, even though this reduction was not significant statistically (p = 0.37) (Fig. 7).

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PMC8540611

They were preincubated for 24 h and a further 72 h after adding complexes.

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PMC11750165

Products from heteroduplex analysis were electrophoresed on 2% agarose gels (Invitrogen).

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PMC6889484

Co-expression of Vif2 resulted in lower hypermutation frequencies for all three vectors, although a high frequency of hypermutation was still observed for A3G(DK) proviral genomes (40/60 clones).

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PMC9429973

Secondary endpoints were median survival time (MST) and safety.

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PMC11588085

Therefore, XIST KD may protect OVCAR3-KRAB cells from hypoxia-induced cell death probably by increasing the CSC population.

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