Datasets:
OTAR3088
/
BioData-CellLine_annotated

Dataset card Data Studio Files
xet
Community
1
PMCID
string
Sentences
string
ner
list
PMC9429973
Myeloid blast combined to DIC suggested acute promyelocitic leukemia presumptive diagnosis but t(15;17) was not found at PCR rapid test.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Myeloid", "blast", ...
PMC11615101
Synovitis is the main pathological feature of RA and fibroblast-like synoviocyte (FLS) is the most important component of the inflamed synovial membrane.12 Recent evidence suggests that these FLS exhibit significant alteration in glucose, lipid, and amino acid metabolism before synovitis onset.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Then, we compare the taxonomic composition of the gut microbiota of patients at different stages of the disease, and we found significant differences in the relative abundance of some microorganisms.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11789597
Antibodies against SLC7A5 (ab305251, 1:1000) and SLC1A5 (608051, 1:1000) were obtained from Abcam (Cambridge, United Kingdom) and BioLegend, respectively.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Most TEAEs were mild and not related to CAN106, and all resolved without any sequelae.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Most", "TEAEs", "were", "mild", "and", "not", "r...
PMC11063646
Briefly, 18 healthy Swiss albino mice weighing 20–25 g were selected and grouped as, Group I (Blank gel treated), Group II (andrographolide treated), and Group III (ANG 12 treated).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11805741
The apoptotic and antimetastatic effects of the extracted carotenoids are tested against the triple negative breast cancer cell line (MDA -MB-231 cells).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "I-CellLine", "O", "B-CellLine", "I-CellLine", ...
PMC9429973
Results: Overall, we detected 598 additional somatic variants.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", ":", "Overall", ",", "we", "detected", "598", "additional", "somatic", "variants", ...
PMC11538390
b Scattered dot plot of relative luciferase activity for non-risk and risk alleles of rs556188853 and rs570516915 in HEKn cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "b", "Scattered", "d...
PMC8916024
For α-diversity analysis, Chao1, Simpson, and all other α-diversity indices were calculated using QIIME (Caporaso et al., 2010).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11064533
Profiles of the transcriptome and proteome allowed the differentiation between adhered bacteria in clumps and planktonic bacteria in the supernatant.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Profiles", "of", "the", ...
PMC10969097
Cancer is a health crisis that deeply affects people worldwide.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cancer", "is", "a", "health", "crisis", "that", "deeply", "affects", "people", "worldwide", ...
PMC11267830
a The drug sensitivity of primary cells treated with gradient concentrations of indisulam for 48 h was determined.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "a", "The", "drug", "sensitivity", "of"...
PMC8409415
In A2780 mock cells, the expression of NF‐κB‐p65 and phospho‐NF‐κB‐p65 was induced after cisplatin exposure and CD70 expression was also induced after cisplatin exposure.
[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ],...
PMC11656657
Furthermore, CAR + T-cells remained stable overtime (Fig. 3K).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Furthermore", ",", "CAR", "+", "T-cells", "remained", "stable", "overtime",...
PMC11538390
Individual and combined PAR of risk variants were calculated as described previously, using the following formulas:1[12pt] $$}=1-)^+2p(1-p)^+^^}$$=1−1(1−p)2+2p1−peβ+p2e2βwhere p is the population frequency of the risk allele and β is the beta coefficient from the regression analysis, which shows the effect size of the variant on the phenotype and e expresses odds ratio (OR), and2[12pt] $$}}}_}}=1-}}_(1-}}}_)$$=1−IIi1−PARiwhere the risk variants are assumed to be independent of one another and that their combined effects on disease are multiplicative.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11539788
Based on these findings, we concluded that RNF19A could directly interact with ILK and target ILK as a ubiquitination substrate.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Based", "on", "th...
PMC7305184
In each generation efficiency of survival of CTRL () group was compared to samples exposed to electric pulses (EP group, ).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC8873393
How the repression is inactivated to allow transcription to recover is still largely unknown.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "How", "the", "repression", "is", "inactivated", "to", "allow", "...
PMC11502327
The development of NNDDS enables targeted delivery of hydrophobic components of natural drugs driven by specific ligand functions, preferentially acting on OC cells and releasing the drug into tumor tissue.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10978090
At this time point, a treatment with dual antiplatelet therapy using aspirin and clopidogrel, and rivaroxaban 20 mg per day was started.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC10957991
As expression of TRPV4 is dependent on the mechanical features of the cell microenvironment and there are indications that TRPV4 activity is also regulated through biophysical changes (Fig. 1G,H), we performed experiments on various compliances to investigate the possible role of TRPV4 in stiffness-dependent differentiation of the mammary epithelial cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11321678
Lastly, new fragments were used as the input of ArchR to create arrow files.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Lastly", ",", "new", "fragments", "were", "used", "as", ...
PMC10495912
In the present study, TQ alone could significantly increase the activity of CAT and SOD in HepG2 cells, which is in the line with the findings of Woo et al. (2013).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11380454
The 96-well plates were coated with 80 μL of VCAM-1 (1 mg/ml) or BSA (2%).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "96-well", "plates", ...
PMC11726848
The purpose of our study is to compare the mechanisms of cell response to LDR and HDR corpuscular irradiations.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "purpose", "of", "our", ...
PMC10482220
Efficiency of recruitment to SGs.
[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Efficiency", "of", "recruitment", "to", "SGs", "." ] } ]
PMC11721587
The nuclei were collected by 1000g centrifugation for 15 min and washed twice with lysis buffer.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "nuclei", "were", "collected", "by", ...
PMC11473843
Scale bar: 100 μm; n mice/group: 3, 3, 4, 4.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bar", ":", "100", "μm", ";", "n", ...
PMC8903741
We used ProCHO5 as a culture medium by considering the production cost.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "used", "ProCHO5", "as", "a", "culture", "medium", "by", "considering", ...
PMC9541067
a–c Forty-eight hours after plasmid or vector transfection, qPCR detected the expression level of 3 genes in both OSRC-2 and A498 cell lines.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "...
PMC7685376
Relative mRNA levels of MCM2, MCM3, MCM4, MCM5, MCM6, and MCM7 in SK-Hep1 and Bel-7404 cell lines treated with Huaier (15 mg/mL) for 24h (Student’s t-test, n = 3).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "...
PMC11519788
Given the established importance of infiltrated macrophages in the suppression of UBC cell proliferation and stemness by SPOP, and considering the opposing roles of M1-like and M2-like macrophages in tumor growth 22, we assessed the mRNA levels of macrophage biomarkers, including the pan-marker (CD68), M1 marker (CD86 and iNOS), and M2 markers (CD163, CD206 and CCL22) in U937 cells co-cultured with UBC cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Results: Among 150 eligible patients, the mean age at FEDR initiation was 68 years (range, 36–85).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", ":", "A...
PMC11594074
This indicates that these complexes have moderate interaction stability.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "indicates", "that", "these", "complexes", "have", "moderate", "interaction", "stability", "." ]...
PMC11679033
Nevertheless, in this preliminary phase of the research, our main objective was to provide novel and interesting evidence that could represent a solid basis for planning future research and determine in which direction it must continue.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10955424
Chemoresistance frequently occurs in OC patients due to several mechanisms, including reduced platinum accumulation within the cancer cells, increased drug inactivation by metallothionein and glutathione, and increased DNA-repair activity .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11522251
p < 0.01, OE group relative to EV group.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "p", "<", "0.01", ",", "OE", "group", "relative", "to", "EV", "group", "." ] } ]
PMC11472569
Inhibiting EVs might inadvertently disrupt beneficial immune responses, potentially leading to tumor progression or immune-related side effects.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Inhibiting", "EVs", "might", "inadvertently"...
PMC10079526
Our data highlight DNA methylases and DNA damage response factors as 5-Aza-2’ responsive SUMO2 targets.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Our", "data", "highlight", "DNA", "methylases", "and",...
PMC6312945
SPSS 19.0 (Asia Analytics, formerly SPSS China) was used for statistical analysis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "SPSS", "19.0", "(", "Asia", "Analytics", ",", "formerly", ...
PMC11463018
White solid, 74.5% yield.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "White", "solid", ",", "74.5", "%", "yield", "." ] } ]
PMC11394386
Finally Western blots were performed for respective components of the PI3K/AKT signaling pathway, PI3K (Cell signal.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Finally", "Western", "blots", "we...
PMC11767725
AD is strongly associated with microbial dysbiosis, characterized by overgrowth of S. aureus and diminished diversity of commensal microbes.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "AD", "is", "strongly", ...
PMC11748363
Tables with full results can be found in the Data S1.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Tables", "with", "full", "results", "can", "be", "found", "in", "the", "Data", ...
PMC11731161
E The kaplan–Meier analysis showed that higher USP7 expression in MM patients correlated with shorter OS in coMMpass (n = 761), GSE24080 (n = 554) and GSE2658 (n = 559) cohorts.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11585565
Cells were collected before treatment (0 h) and after treatment for 2, 4, 8, 12 and 24 h. The CNNM4 mRNA and protein were measured using RT-qPCR and Western blot, respectively.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Here we present our experience of AL amyloidosis diagnosis and treatment in the era of modern diagnostics and therapy with novel agents.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Here", "we",...
PMC10578720
The acetylation levels of CS and PDHC in macrophages were elevated with increased HBV titers (Figure 1C).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "acetylation", "levels", "o...
PMC11411004
ns, the difference was not significant. **
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ns", ",", "the", "difference", "was", "not", "significant", ".", "*", "*" ] } ]
PMC10040136
In order to further scrutinize the mechanism behind TGF-β2-induced GIST drug resistance, we examined the impact of contact-CM on the PI3K-AKT signaling pathway of GIST.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11697703
Also, since spine morphology (class) is correlated to spine stability and synaptic maturity, we analyzed whether specific classes of spines were differentially affected by decreased MAPK8 signal after miR-193b or -365 expression.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11297139
The nuclear boundaries of cells were detected manually.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "nuclear", "boundaries", "of", "cells", "were", "detected", "manually", "." ] } ]
PMC11319300
Here, the darker the colour, the more frequently two genomic loci were found proximal within a population of simulated chromatin configurations. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11680562
The peak at 3278 cm corresponds to the stretching vibration of the O–H group of carboxylic acid, indicative of surface functionalization (Table 2).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11792766
Finally, the optical density (absorbance) was measured at 540 nm using a SpectraMax iD3 plate reader (Molecular Devices).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Finally...
PMC9693627
The molecular mechanisms governing the expression of each individual human mitochondrial mRNA and orchestrating its cross-talk with cytosolic translation are poorly studied.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "molec...
PMC9429973
First relapse therapy for 17 patients who progressed during LenM included: KD(n=11) 64.7%, dara(n=2) 11.7%, pomalidomide(n=1) 5.8%, and RV(n=2) 11.7% and VCD(n=1) 5.8%.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11743975
An orbital shaker was used to mix the contents and induce cell lysis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "An", "orbital", "shaker", "was", "used", "to", "mix", "the", "content...
PMC11348300
O, P, and Q) show the corresponding CBR and HS values over time.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "O", ",", "P", ",", "and", "Q", ")", "show"...
PMC11441402
Mosmann stated that the amount of formazan is directly proportionate to the cell number, when more accurately it is proportionate to the activity of their cellular oxidoreductases that reduce MTT.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11544122
P-values are indicated.
[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "P-values", "are", "indicated", "." ] } ]
PMC11678368
For the Pt(II) complex with 5ClL, a similar band pattern is observed with the bands at 1680 cm and 1672 cm, attributed to Fermi resonance and the C8=O1 aldehyde stretching vibration, respectively.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11655498
BGLF2 enhances Zta expression in both B cells and gastric cancer cells, promoting the release of progeny viruses through the p38 signaling pathway.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973
Our results are in accordance with the SEAL analysis, although our sample was significantly smaller and SEAL included other immunochemotherapy regimens.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Our", "resul...
PMC11638255
4The neuroblastoma tumor microenvironment is sensitive to copper chelation therapy and promotes neutrophil infiltration.a Experimental design and tumor processing workflow for single-cell RNA sequencing.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11011020
Consequently, understanding the tumour microenvironment is crucial to decipher the factors influencing metastasis and treatment responses.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Consequently", ",", "understanding", "the", "tumo...
PMC6889484
No NL4-3 virus was detected in the 100% CEMSS/D128K cells (top).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O" ], "tokens": [ "No", "NL4", "-", "3", "virus", ...
PMC11119602
The results presented herein also add a new dimension to the increasingly established role for TG2-S, rather than the TG2-L isoform, as the arbiter of cell death, but, in this case, only following its release from a membrane-bound pool.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11391695
In a similar fashion, qRT-PCR and western blotting were utilized to confirm their interaction at the molecular and protein levels; these techniques revealed that KCNN4 expression was upregulated subsequent to ACYP2 knockdown and downregulated subsequent to its overexpression (Fig. 3C, D).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
T. Zhang Haematopoietic Stem Cell Transplantation centre, Institute of Haematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China Background: Allogeneic hematopoietic cell transplantation (allo-HSCT) is potentially curative for patients with chronic myelomonocytic leukemia (CMML), however, few data exist regarding prognostic factors and transplant outcomes regarding Chinese.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9684669
Importantly, calcium signaling-related pathways were shown to be aberrantly regulated in MDR cells, indicating that calcium homeostasis was disrupted.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Importantly", ",", ...
PMC11518994
B Western blot analysis of Pax-5 expression.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "B", "Western", "blot", "analysis", "of", "Pax-5", "expression", "." ] } ]
PMC11075223
C. heracleifolia extract (0.1, 1, 10 μg/mL) enhanced the proliferation and osteogenic differentiation of human mesenchymal stem cells isolated from periodontal tissue .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11543935
The treatment is evaluated with an AlamarBlue assay and the temperature is monitored with a sensor and a non-invasive MR-thermometry.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "treatment", "is", ...
PMC6114978
To detect reconstitution of the Hippo kinases, either 5 or 10 μM 5-azacytidine (Sigma-Aldrich) was added to cell lines for 4 days.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10808409
Pluronic F127 (F127), Pluronic P123 (P123), and D-α-tocopheryl polyethylene glycol 1000 succinate (TPGS) were purchased from Sigma-Aldrich Chemical Co. (St. Louis, IL, USA).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10993311
The Shapiro-Wilk test was applied to verify data normality.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "Shapiro-Wilk", "test", "was", "applied", "to", "verify", "data", "normality", "." ] } ]
PMC8316344
E βTrCP but not Smurf1 and COP1 was required for TRIB2 to reduce TFRC in SK-Hep1 cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "E", "βTrCP", "but", "not", "Smurf1", ...
PMC11525293
Human lung carcinoma H1299 cells that do not express any of the p63 isoforms were used as further negative control.
[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Human", "lung", "ca...
PMC11754784
Fig. 6Shielding the interference of erythrocyte and enhancing the phagocytosis of macrophages.a Flow cytometry analysis of the segregation effect of DNP3 in shielding the interference of erythrocyte.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11519077
An essential part of the etiology of IBD is played by the proinflammatory mediator TNF-α.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "An", "essential", "part", "of", "the", "etiology", "of", ...
PMC11269933
Phosphorylation is one of the most extensively studied PTMs, which integrates signal transduction, gene expression, and metabolism in biological stress responses by influencing conformational changes and localization to regulate the substrate binding capacity of glycolytic enzymes and control more central metabolism than do changes in protein abundance.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10165258
Following the validation of the single-drug screen, combination of etoposide and cisplatin against EwS spheroids was evaluated with the same fluorescent barcoding strategy as the single drug experiments.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11727062
Its pharmacological effects include enhancing the body’s immune system, improving physical stamina, and promoting metabolic processes.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Its", "pharmacological", "effects", ...
PMC9429973
Aims: We performed a cross-trial analysis to evaluate outcomes with fixed-duration I+V relative to FCR using data from the FD cohort of the CAPTIVATE study and the FCR arm of the recent E1912 study (NCT02048813; Shanafelt et al. NEJM 2019;381:432-43).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11701801
SMARCB1 is included in cBAF and PBAF.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "SMARCB1", "is", "included", "in", "cBAF", "and", "PBAF", "." ] } ]
PMC10747139
KP1019 is known to be active against primary tumors, while NAMI-A is active against secondary tumors via antiangiogenic and antimetastatic activities .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "KP1019", "is...
PMC9429973
tSNE analysis showed that CD4 T cells were more abundant in C2 compared to C1 while the opposite was observed for CD8 T cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC8592717
PCA has the potential to counter oxidative stress, excitotoxicity, and neuroinflammatory and nitrosative stress effects .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "PCA", "has", "the", "potential", "to", "cou...
PMC9429973
Our Phase 1 study provides evidence for feasibility and safety of HSP-CAR30.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Our", "Phase", "1", "study", "provides", "evidence", "for", "feasibility", "and"...
PMC11342785
However, connecting these two activities together using TPPP-IDR-PixD/E synMAP fusion proteins led to robust and constitutive assembly of large synthetic MT architectures (Fig. 4B).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Aims: The International Haemoglobinopathy Research Network (INHERENT) is a recently established network with the aim of investigating the role of genetic modifiers in haemoglobinopathies, through a large-scale, multi-ethnic genome-wide association study (GWAS).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8414691
Spastin is a key player in microtubule severing, ensuring the final cut at the midbody, whereas α-Tubulin is a major component of spindle and midbody microtubules.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11519583
Male C57BL/6N mice (8–12 weeks of age, 20–25 g body weight) were purchased from Japan SLC (Shizuoka, Japan).
[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "token...
PMC9429973
Noteworthy, 14/31 (45.2%) of all DH/THL and 3/6 (50%) of LBDCG NOS had an IGH partner.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Notewor...
PMC11486946
Verteporfin exhibited high KLD values (red dot).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Verteporfin", "exhibited", "high", "KLD", "values", "(", "red", "dot", ")", "." ] } ]
PMC9429973
Methods: NXG mice were injected intraperitoneally with hPBMC from healthy donors and xenografted with MOLM-13 cells subcutaneously two days after hPBMC injection.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11604830
Ex vivo H‐CSI and confocal fluorescence microscopy of PLNs after PFCE‐NE injection in the footpad.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Ex", "vivo", "H‐CSI", "and", "confocal", "fluorescence", "m...
PMC11534035
The discrepancy between their findings and ours, is possibly explained by A431 cells exhibiting varying responses to different doses of treatment, with lower doses promoting viability and higher doses restricting proliferation and inducing toxicity.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...