OTAR3088/BioData-CellLine_annotated · Datasets at Hugging Face

PMCID string	Sentences string	ner list
PMC9429973	GATLA is designing a trial with the aim to improve these two different risk groups.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "GATLA", "is", "designing", "a", "trial", "with", "the", "aim", "to", "improve", "these", "two", "different", "risk", "groups", "." ] } ]
PMC11615743	These devices allow for simultaneous analysis of multiple cell surface proteins, achieving greater specificity in cell identification and isolation than D‐DNA‐based logic devices.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "devices", "allow", "for", "simultaneous", "analysis", "of", "multiple", "cell", "surface", "proteins", ",", "achieving", "greater", "specificity", "in", "cell", "identification", "and", "isolation", "than", "D‐DNA‐based", "logic", "devices", "." ] } ]
PMC10213179	After 72 h of aptamer injection, mice were euthanized and ex vivo fluorescence in tumor, heart, liver, kidneys, and spleen was measured.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "72", "h", "of", "aptamer", "injection", ",", "mice", "were", "euthanized", "and", "ex", "vivo", "fluorescence", "in", "tumor", ",", "heart", ",", "liver", ",", "kidneys", ",", "and", "spleen", "was", "measured", "." ] } ]
PMC11786767	Scale bars represent (A) 10 μm; (B and D) whole cells: 5 μm; enlarged segment: 0.5 μm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bars", "represent", "(", "A", ")", "10", "μm", ";", "(", "B", "and", "D", ")", "whole", "cells", ":", "5", "μm", ";", "enlarged", "segment", ":", "0.5", "μm", "." ] } ]
PMC9429973	Samples were analyzed at each local site according to ICSH guidelines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Samples", "were", "analyzed", "at", "each", "local", "site", "according", "to", "ICSH", "guidelines", "." ] } ]
PMC11483468	The apoptosis of Hela cells was measured by flow cytometry.	[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "apoptosis", "of", "Hela", "cells", "was", "measured", "by", "flow", "cytometry", "." ] } ]
PMC11474209	Optical biosensors based on QD-FRET are often employed in immunoassays, diagnostic tests, and assessments of biomolecular interaction.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Optical", "biosensors", "based", "on", "QD-FRET", "are", "often", "employed", "in", "immunoassays", ",", "diagnostic", "tests", ",", "and", "assessments", "of", "biomolecular", "interaction", "." ] } ]
PMC11461833	The translation of STXBP5 was evaluated with an anti-STXBP5 antibody, with normalized to -Actin expression. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "translation", "of", "STXBP5", "was", "evaluated", "with", "an", "anti-STXBP5", "antibody", ",", "with", "normalized", "to", "-Actin", "expression", ".", "(" ] } ]
PMC9964635	C NMR (101 MHz, CDCl3) δ 175.22 (C=O), 140.49 (C-1), 137.63 (C-4), 129.04 (C-2 & C-6), 127.31 (C-3 & C-5), 52.09 (OCH3), 44.99 (CH2-9), 40.11 (CH-7), 30.25 (CH-10), 22.21 (CH3-11 & CH3-12), 18.50 (CH3-8).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "C", "NMR", "(", "101", "MHz", ",", "CDCl3", ")", "δ", "175.22", "(", "C", "=", "O", ")", ",", "140.49", "(", "C-1", ")", ",", "137.63", "(", "C-4", ")", ",", "129.04", "(", "C-2", "&", "C-6", ")", ",", "127.31", "(", "C-3", "&", "C-5", ")", ",", "52.09", "(", "OCH3", ")", ",", "44.99", "(", "CH2", "-", "9", ")", ",", "40.11", "(", "CH-7", ")", ",", "30.25", "(", "CH-10", ")", ",", "22.21", "(", "CH3", "-", "11", "&", "CH3", "-", "12", ")", ",", "18.50", "(", "CH3", "-", "8)", "." ] } ]
PMC9429973	VTE included all symptomatic or incidentally diagnosed cases of pulmonary embolism (PE), deep vein thrombosis (DVT) and thrombosis in unusual sites (cerebral, mesenteric, portal, splenic, hepatic, and renal veins).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "VTE", "included", "all", "symptomatic", "or", "incidentally", "diagnosed", "cases", "of", "pulmonary", "embolism", "(", "PE", ")", ",", "deep", "vein", "thrombosis", "(", "DVT", ")", "and", "thrombosis", "in", "unusual", "sites", "(", "cerebral", ",", "mesenteric", ",", "portal", ",", "splenic", ",", "hepatic", ",", "and", "renal", "veins", ")", "." ] } ]
PMC8916024	This provides guidance for future studies on the interaction between the gut flora of snails and their environment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "provides", "guidance", "for", "future", "studies", "on", "the", "interaction", "between", "the", "gut", "flora", "of", "snails", "and", "their", "environment", "." ] } ]
PMC10329074	After drawing two horizontal lines on the back of the 12-well plates (Thermo Fisher Scientific, USA), 1.5 × 10 cells either silenced for the YBX3 gene or overexpressing the YBX3 gene were added, according to the experimental design groups.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "drawing", "two", "horizontal", "lines", "on", "the", "back", "of", "the", "12-well", "plates", "(", "Thermo", "Fisher", "Scientific", ",", "USA", ")", ",", "1.5", "×", "10", "cells", "either", "silenced", "for", "the", "YBX3", "gene", "or", "overexpressing", "the", "YBX3", "gene", "were", "added", ",", "according", "to", "the", "experimental", "design", "groups", "." ] } ]
PMC11786156	IPI-H cases included five of the 10 available cases, and clinical stage IV cases were five of the 11 available cases.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "IPI-H", "cases", "included", "five", "of", "the", "10", "available", "cases", ",", "and", "clinical", "stage", "IV", "cases", "were", "five", "of", "the", "11", "available", "cases", "." ] } ]
PMC11021472	To further understand the growth supporting role of circZDHHC11, we determined whether it could influence gene expression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "further", "understand", "the", "growth", "supporting", "role", "of", "circZDHHC11", ",", "we", "determined", "whether", "it", "could", "influence", "gene", "expression", "." ] } ]
PMC11763126	Fig. 10CBDP1 Inhibits ccRCC Progression In vivo.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fig.", "10CBDP1", "Inhibits", "ccRCC", "Progression", "In", "vivo", "." ] } ]
PMC8358006	For IMR90 cell datasets downloaded in BAM format from the ENCODE databases (https://www.encodeproject.org/), the reads were mapped to the human reference genome version hg38.	[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "IMR90", "cell", "datasets", "downloaded", "in", "BAM", "format", "from", "the", "ENCODE", "databases", "(", "https://www.encodeproject.org/", ")", ",", "the", "reads", "were", "mapped", "to", "the", "human", "reference", "genome", "version", "hg38", "." ] } ]
PMC11653533	The crude aqueous extract of F. racemosa demonstrated the highest efficacy against the larvae of C. quinquefasciatus and C. gelidus, with LC50 values of 67.72 and 63.70 mg/L, respectively (Velayutham et al., 2013).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "crude", "aqueous", "extract", "of", "F.", "racemosa", "demonstrated", "the", "highest", "efficacy", "against", "the", "larvae", "of", "C.", "quinquefasciatus", "and", "C.", "gelidus", ",", "with", "LC50", "values", "of", "67.72", "and", "63.70", "mg/L", ",", "respectively", "(", "Velayutham", "et", "al.", ",", "2013", ")", "." ] } ]
PMC10777969	Additionally, FCP26 with a 2-thiazoline motif linked to the sugar moiety via the nitrogen bridge was studied using single-crystal X-ray crystallography.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "FCP26", "with", "a", "2-thiazoline", "motif", "linked", "to", "the", "sugar", "moiety", "via", "the", "nitrogen", "bridge", "was", "studied", "using", "single-crystal", "X-ray", "crystallography", "." ] } ]
PMC11317131	The remaining single-stranded sequence of the att sites can subsequently be filled in to promote insertion of the full att site (22).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "remaining", "single-stranded", "sequence", "of", "the", "att", "sites", "can", "subsequently", "be", "filled", "in", "to", "promote", "insertion", "of", "the", "full", "att", "site", "(", "22", ")", "." ] } ]
PMC11515150	In recent years, CAR-NK cells have been a hopeful strategy to avoid fratricide.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "recent", "years", ",", "CAR-NK", "cells", "have", "been", "a", "hopeful", "strategy", "to", "avoid", "fratricide", "." ] } ]
PMC10165258	Second, the PI fluorescent intensity is integrated over this PI mask.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Second", ",", "the", "PI", "fluorescent", "intensity", "is", "integrated", "over", "this", "PI", "mask", "." ] } ]
PMC11740399	Wang et al. reported that the receptor of long-chain free fatty acids (FFAs), G protein-coupled receptor 120 (GPR120), was highly expressed in primary breast cancer treated by chemotherapy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Wang", "et", "al.", "reported", "that", "the", "receptor", "of", "long-chain", "free", "fatty", "acids", "(", "FFAs", ")", ",", "G", "protein-coupled", "receptor", "120", "(", "GPR120", ")", ",", "was", "highly", "expressed", "in", "primary", "breast", "cancer", "treated", "by", "chemotherapy", "." ] } ]
PMC10507284	The proliferation, migration, and invasion abilities of the SW982 cells were inhibited with the downregulation of TROAP. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "proliferation", ",", "migration", ",", "and", "invasion", "abilities", "of", "the", "SW982", "cells", "were", "inhibited", "with", "the", "downregulation", "of", "TROAP", ".", "(" ] } ]
PMC11078693	This staining will increase background in the wide-field fluorescence imaging, but not in confocal microscopy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "staining", "will", "increase", "background", "in", "the", "wide-field", "fluorescence", "imaging", ",", "but", "not", "in", "confocal", "microscopy", "." ] } ]
PMC11420784	Scale bar, 5 μm.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bar", ",", "5", "μm", "." ] } ]
PMC11413393	Epiprobes were dissolved in DMSO and added to achieve a final concentration as indicated in Fig. 1a.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Epiprobes", "were", "dissolved", "in", "DMSO", "and", "added", "to", "achieve", "a", "final", "concentration", "as", "indicated", "in", "Fig.", "1a", "." ] } ]
PMC11635519	Notably, PepA3 and its two related variants, PepA and PepA2, stimulated the GLP-1R receptor with lesser potency but the same efficacy as GLP-1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Notably", ",", "PepA3", "and", "its", "two", "related", "variants", ",", "PepA", "and", "PepA2", ",", "stimulated", "the", "GLP-1R", "receptor", "with", "lesser", "potency", "but", "the", "same", "efficacy", "as", "GLP-1", "." ] } ]
PMC9784246	The total methanolic extract, as well as its different fractions, were investigated against lung cancer cell line (A549) using the 3-(4,5-dimethythiazol-2yl)-2,5-diphenyltetrazolium bromide (MTT) cell viability assay method.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "total", "methanolic", "extract", ",", "as", "well", "as", "its", "different", "fractions", ",", "were", "investigated", "against", "lung", "cancer", "cell", "line", "(", "A549", ")", "using", "the", "3-(4,5-dimethythiazol-2yl)-2,5-diphenyltetrazolium", "bromide", "(", "MTT", ")", "cell", "viability", "assay", "method", "." ] } ]
PMC11612315	Interactions between exendin 9–39 and TRPV1 were examined via His-mediated pull-down assays using a modified protocol from the Pierce Pull-down PolyHis Protein:Protein Interaction Kit (Thermo Fisher Scientific).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Interactions", "between", "exendin", "9–39", "and", "TRPV1", "were", "examined", "via", "His-mediated", "pull-down", "assays", "using", "a", "modified", "protocol", "from", "the", "Pierce", "Pull-down", "PolyHis", "Protein", ":", "Protein", "Interaction", "Kit", "(", "Thermo", "Fisher", "Scientific", ")", "." ] } ]
PMC10507284	Subsequently, DYRK1 in the cytoplasm activates Akt/GSK‐3β signaling, enhancing the stability and nuclear localization of cyclin D1, thereby accelerating cell cycle progression and facilitating the malignant proliferation of HCC.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Subsequently", ",", "DYRK1", "in", "the", "cytoplasm", "activates", "Akt/GSK‐3β", "signaling", ",", "enhancing", "the", "stability", "and", "nuclear", "localization", "of", "cyclin", "D1", ",", "thereby", "accelerating", "cell", "cycle", "progression", "and", "facilitating", "the", "malignant", "proliferation", "of", "HCC", "." ] } ]
PMC3035438	We described in this report new DT40 strains designed to express chimeric IgG antibodies containing chicken antigen-binding regions and human constant regions of the IgG isoform.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "described", "in", "this", "report", "new", "DT40", "strains", "designed", "to", "express", "chimeric", "IgG", "antibodies", "containing", "chicken", "antigen-binding", "regions", "and", "human", "constant", "regions", "of", "the", "IgG", "isoform", "." ] } ]
PMC9436459	Except for compounds 130, 131, and 135, the absolute configurations of C-2 and C-3 of 128, 129, and 132 − 134 have not been determined.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Except", "for", "compounds", "130", ",", "131", ",", "and", "135", ",", "the", "absolute", "configurations", "of", "C-2", "and", "C-3", "of", "128", ",", "129", ",", "and", "132", "−", "134", "have", "not", "been", "determined", "." ] } ]
PMC10452486	While constituting liposomes, they observed the self-association or clustering of fluorescinated Face-2 of HLA-A2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "While", "constituting", "liposomes", ",", "they", "observed", "the", "self-association", "or", "clustering", "of", "fluorescinated", "Face-2", "of", "HLA-A2", "." ] } ]
PMC9250505	Kaplan–Meier survival analysis was also performed in the EOC patient cohort, which sub-categorized the level of BADS99 as low or high using a receiver operating characteristic curve (Supplementary Fig. 1A, B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Kaplan", "–", "Meier", "survival", "analysis", "was", "also", "performed", "in", "the", "EOC", "patient", "cohort", ",", "which", "sub-categorized", "the", "level", "of", "BADS99", "as", "low", "or", "high", "using", "a", "receiver", "operating", "characteristic", "curve", "(", "Supplementary", "Fig.", "1A", ",", "B", ")", "." ] } ]
PMC9436459	Over the past four decades, a total of 166 MDAAs including 150 classic (90%) and 16 non-classic (10%) ones have been described, of which dehydroprenyl-2-arylbenzofuran-, dehydroprenylstilbene-, dehydroprenylchalcone-, dehydroprenylflavone-, dehydroprenyldihydroflavone-, dehydroprenylsanggenonflavone-, dehydroprenylcoumarin-, and simple or other dehydroprenylphenol-types, are the eight subtypes (Types A − H) of the classic MDAAs with the same chalcone-skeleton dienophiles.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Over", "the", "past", "four", "decades", ",", "a", "total", "of", "166", "MDAAs", "including", "150", "classic", "(", "90", "%", ")", "and", "16", "non-classic", "(", "10", "%", ")", "ones", "have", "been", "described", ",", "of", "which", "dehydroprenyl-2-arylbenzofuran-", ",", "dehydroprenylstilbene-", ",", "dehydroprenylchalcone-", ",", "dehydroprenylflavone-", ",", "dehydroprenyldihydroflavone-", ",", "dehydroprenylsanggenonflavone-", ",", "dehydroprenylcoumarin-", ",", "and", "simple", "or", "other", "dehydroprenylphenol-types", ",", "are", "the", "eight", "subtypes", "(", "Types", "A", "−", "H", ")", "of", "the", "classic", "MDAAs", "with", "the", "same", "chalcone-skeleton", "dienophiles", "." ] } ]
PMC11047729	Moreover, it increases cells’ susceptibility to ATRA, causing ATRA-induced differentiation, cell elimination, and senescence.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "it", "increases", "cells", "’", "susceptibility", "to", "ATRA", ",", "causing", "ATRA-induced", "differentiation", ",", "cell", "elimination", ",", "and", "senescence", "." ] } ]
PMC9895440	A donor-paired design matrix an edgeR functions glmQLFit, glmQLFTest, and topTags were used to investigate all significantly dysregulated genes among any conditions (ANOVA-like, Supplementary Data 1) or between each combination of conditions (Supplementary Data 2).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "donor-paired", "design", "matrix", "an", "edgeR", "functions", "glmQLFit", ",", "glmQLFTest", ",", "and", "topTags", "were", "used", "to", "investigate", "all", "significantly", "dysregulated", "genes", "among", "any", "conditions", "(", "ANOVA-like", ",", "Supplementary", "Data", "1", ")", "or", "between", "each", "combination", "of", "conditions", "(", "Supplementary", "Data", "2", ")", "." ] } ]
PMC11585994	T cell activation was conducted using the T Cell TransAct kit (Miltenyi Biotec, 130–111-160) according to the manufacturer’s instructions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "T", "cell", "activation", "was", "conducted", "using", "the", "T", "Cell", "TransAct", "kit", "(", "Miltenyi", "Biotec", ",", "130–111", "-", "160", ")", "according", "to", "the", "manufacturer", "’s", "instructions", "." ] } ]
PMC8270637	TGF-β1-treated/untreated activated T cells were co-cultured with SMMC-7721 cells or cultured separately for 24 h; subsequently, the apoptosis rate of T cells was detected by flow cytometry. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "TGF-β1-treated/untreated", "activated", "T", "cells", "were", "co-cultured", "with", "SMMC-7721", "cells", "or", "cultured", "separately", "for", "24", "h", ";", "subsequently", ",", "the", "apoptosis", "rate", "of", "T", "cells", "was", "detected", "by", "flow", "cytometry", ".", "(" ] } ]
PMC11765988	Cigarette smoking is linked to lymphoma formation (NHL and HL) and especially to the follicular form .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cigarette", "smoking", "is", "linked", "to", "lymphoma", "formation", "(", "NHL", "and", "HL", ")", "and", "especially", "to", "the", "follicular", "form", "." ] } ]
PMC11240448	Interestingly, certain cell lines within this group, such as MDA-MB-157, exhibit notable resistance to MEK inhibitors .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Interestingly", ",", "certain", "cell", "lines", "within", "this", "group", ",", "such", "as", "MDA-MB-157", ",", "exhibit", "notable", "resistance", "to", "MEK", "inhibitors", "." ] } ]
PMC11122631	For the pharmacokinetics of the compounds, we performed in silico predictions of gastrointestinal absorption, blood–brain barrier permeation, P-glycoprotein substrate, inhibitors for cytochrome P450, and skin permeation (Table S18).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "the", "pharmacokinetics", "of", "the", "compounds", ",", "we", "performed", "in", "silico", "predictions", "of", "gastrointestinal", "absorption", ",", "blood", "–", "brain", "barrier", "permeation", ",", "P-glycoprotein", "substrate", ",", "inhibitors", "for", "cytochrome", "P450", ",", "and", "skin", "permeation", "(", "Table", "S18", ")", "." ] } ]
PMC11706297	This therapy targets the specific oncogenes and signaling pathways that play a critical role in gene expression, apoptosis, and the cell cycle.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "therapy", "targets", "the", "specific", "oncogenes", "and", "signaling", "pathways", "that", "play", "a", "critical", "role", "in", "gene", "expression", ",", "apoptosis", ",", "and", "the", "cell", "cycle", "." ] } ]
PMC8097906	Briefly, cells were 48 h adapted in assay medium and further treated for 48 h with different concentrations of plant extract (VSM and LW) and plant-derived compounds (Geni, Seco, Mata, Daid and Jaspl.).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Briefly", ",", "cells", "were", "48", "h", "adapted", "in", "assay", "medium", "and", "further", "treated", "for", "48", "h", "with", "different", "concentrations", "of", "plant", "extract", "(", "VSM", "and", "LW", ")", "and", "plant-derived", "compounds", "(", "Geni", ",", "Seco", ",", "Mata", ",", "Daid", "and", "Jaspl", ".", ")", "." ] } ]
PMC11511922	All data represent one set of triplicates.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "data", "represent", "one", "set", "of", "triplicates", "." ] } ]
PMC10907726	Next, we further estimated whether autophagy inhibitor 3-MA could reverse the effect of DATS on OS cells growth, migration, invasion and EMT.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Next", ",", "we", "further", "estimated", "whether", "autophagy", "inhibitor", "3-MA", "could", "reverse", "the", "effect", "of", "DATS", "on", "OS", "cells", "growth", ",", "migration", ",", "invasion", "and", "EMT", "." ] } ]
PMC11684269	Furthermore, DKD involves damage to both glomeruli and tubules.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Furthermore", ",", "DKD", "involves", "damage", "to", "both", "glomeruli", "and", "tubules", "." ] } ]
PMC9429973	Also, we report an association between the progression free survival time and expression level at diagnosis of SERPINA2, RPS26 and UBBP4, suggesting their potential as prognosis biomarkers.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Also", ",", "we", "report", "an", "association", "between", "the", "progression", "free", "survival", "time", "and", "expression", "level", "at", "diagnosis", "of", "SERPINA2", ",", "RPS26", "and", "UBBP4", ",", "suggesting", "their", "potential", "as", "prognosis", "biomarkers", "." ] } ]
PMC11361748	One-way ANOVA.	[ { "tags": [ "O", "O", "O" ], "tokens": [ "One-way", "ANOVA", "." ] } ]
PMC11600602	The keratinocyte is not an exclusively cutaneous cell type.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "keratinocyte", "is", "not", "an", "exclusively", "cutaneous", "cell", "type", "." ] } ]
PMC5716223	a Myogenin and b MyHC isoforms expression at different times of differentiation (2, 5, and 9 days post DM) (9 days: NGF MHC Emb: 2.74 ± 0.17 vs Ctrl MHC Emb: 2.19 ± 0.23; NGF MHC IIB: 2.29 ± 0.11 vs Ctrl MHC IIB: 0.98 ± 0.11; p < 0.05 vs 2 and 5 days; *p < 0.05 vs Ctrl 9d.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "a", "Myogenin", "and", "b", "MyHC", "isoforms", "expression", "at", "different", "times", "of", "differentiation", "(", "2", ",", "5", ",", "and", "9", "days", "post", "DM", ")", "(", "9", "days", ":", "NGF", "MHC", "Emb", ":", "2.74", "±", "0.17", "vs", "Ctrl", "MHC", "Emb", ":", "2.19", "±", "0.23", ";", "NGF", "MHC", "IIB", ":", "2.29", "±", "0.11", "vs", "Ctrl", "MHC", "IIB", ":", "0.98", "±", "0.11", ";", "p", "<", "0.05", "vs", "2", "and", "5", "days", ";", "*", "p", "<", "0.05", "vs", "Ctrl", "9d", "." ] } ]
PMC6181431	To assess whether these genes were enriched in a pathway that might be consistent with resistance to rapalogs, we performed gene set enrichment analysis using hallmark gene sets .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "assess", "whether", "these", "genes", "were", "enriched", "in", "a", "pathway", "that", "might", "be", "consistent", "with", "resistance", "to", "rapalogs", ",", "we", "performed", "gene", "set", "enrichment", "analysis", "using", "hallmark", "gene", "sets", "." ] } ]
PMC11471176	Notwithstanding, meticulous pairwise comparisons between the two compounds demonstrated statistical insignificance across all corresponding concentrations.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Notwithstanding", ",", "meticulous", "pairwise", "comparisons", "between", "the", "two", "compounds", "demonstrated", "statistical", "insignificance", "across", "all", "corresponding", "concentrations", "." ] } ]
PMC11711063	Specific ECM components associated with cell adhesion and ECM development in myoepithelial cells, including fibronectin‐1, versican, laminins and fibulin2, were induced by ZG16B and downregulated by Bex + Carv in HME‐hTert cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "Specific", "ECM", "components", "associated", "with", "cell", "adhesion", "and", "ECM", "development", "in", "myoepithelial", "cells", ",", "including", "fibronectin‐1", ",", "versican", ",", "laminins", "and", "fibulin2", ",", "were", "induced", "by", "ZG16B", "and", "downregulated", "by", "Bex", "+", "Carv", "in", "HME‐hTert", "cells", "." ] } ]
PMC7022782	Once obtained, the purified NP suspension was collected in polyethylene containers and stored at 4 °C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Once", "obtained", ",", "the", "purified", "NP", "suspension", "was", "collected", "in", "polyethylene", "containers", "and", "stored", "at", "4", "°", "C", "." ] } ]
PMC10900886	Gating strategy of EV-D68-inoculated immature dendritic cells (imDCs) co-cultured with autologous B-lymphoblastoid cell line (BLCL).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Gating", "strategy", "of", "EV-D68-inoculated", "immature", "dendritic", "cells", "(", "imDCs", ")", "co-cultured", "with", "autologous", "B-lymphoblastoid", "cell", "line", "(", "BLCL", ")", "." ] } ]
PMC9429973	Patients with other B-cell non-Hodgkin lymphomas (NHL) who failed standard therapy or, in the opinion of the investigator, have no known available options to provide benefit for the patient’s condition, are also eligible.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Patients", "with", "other", "B-cell", "non-Hodgkin", "lymphomas", "(", "NHL", ")", "who", "failed", "standard", "therapy", "or", ",", "in", "the", "opinion", "of", "the", "investigator", ",", "have", "no", "known", "available", "options", "to", "provide", "benefit", "for", "the", "patient", "’s", "condition", ",", "are", "also", "eligible", "." ] } ]
PMC9388315	There was no significant change for 1.25 mg/ml compared to the control group (P > 0.05) (Figure 3(b)).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "There", "was", "no", "significant", "change", "for", "1.25", "mg/ml", "compared", "to", "the", "control", "group", "(", "P", ">", "0.05", ")", "(", "Figure", "3(b", ")", ")", "." ] } ]
PMC11321678	All the qualities described above indicated a good performance of scATAC‐seq in frozen human tissues.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "the", "qualities", "described", "above", "indicated", "a", "good", "performance", "of", "scATAC‐seq", "in", "frozen", "human", "tissues", "." ] } ]
PMC11699042	We thus observed that the A-673 strains demonstrated a 2- to 3-fold smaller variance compared to the carcinoma cell lines, again highlighting the higher stability of the A-673 strains, even considering the larger sample size in the A-673 collection (Supplementary Fig. 1c).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "thus", "observed", "that", "the", "A-673", "strains", "demonstrated", "a", "2-", "to", "3-fold", "smaller", "variance", "compared", "to", "the", "carcinoma", "cell", "lines", ",", "again", "highlighting", "the", "higher", "stability", "of", "the", "A-673", "strains", ",", "even", "considering", "the", "larger", "sample", "size", "in", "the", "A-673", "collection", "(", "Supplementary", "Fig.", "1c", ")", "." ] } ]
PMC9621239	Nonetheless, the underlying mechanism of the different genotypes in the development of HCC remains unknown.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Nonetheless", ",", "the", "underlying", "mechanism", "of", "the", "different", "genotypes", "in", "the", "development", "of", "HCC", "remains", "unknown", "." ] } ]
PMC11680562	The gel was made by adjusting the xanthan gum concentration to assess the sustainable release of the drug.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "gel", "was", "made", "by", "adjusting", "the", "xanthan", "gum", "concentration", "to", "assess", "the", "sustainable", "release", "of", "the", "drug", "." ] } ]
PMC9096373	Cell growth was observed daily using phase-contrast microscopy and the medium was changed every 2 days.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cell", "growth", "was", "observed", "daily", "using", "phase-contrast", "microscopy", "and", "the", "medium", "was", "changed", "every", "2", "days", "." ] } ]
PMC11687663	Strategies to improve its bioavailability and permeability, such as chemical modifications or advanced drug delivery systems, could unlock its potential.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Strategies", "to", "improve", "its", "bioavailability", "and", "permeability", ",", "such", "as", "chemical", "modifications", "or", "advanced", "drug", "delivery", "systems", ",", "could", "unlock", "its", "potential", "." ] } ]
PMC5810978	Current culture systems (BJAB cells or primary human stem cell-derived enteroids) for HuNoVs support modest virus replication.	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Current", "culture", "systems", "(", "BJAB", "cells", "or", "primary", "human", "stem", "cell-derived", "enteroids", ")", "for", "HuNoVs", "support", "modest", "virus", "replication", "." ] } ]
PMC11477621	Compound 5h was prepared using similar procedures as for 3a from compound 4h (296 mg, 1.02 mmol).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Compound", "5h", "was", "prepared", "using", "similar", "procedures", "as", "for", "3a", "from", "compound", "4h", "(", "296", "mg", ",", "1.02", "mmol", ")", "." ] } ]
PMC9672323	The graphs show the mean ± SD.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "graphs", "show", "the", "mean", "±", "SD", "." ] } ]
PMC10587429	Current animal models for ES are mostly subcutaneously injected localized xenograft tumors in immunodeficient mouse hosts (nude, NOD-SCID or NSG).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Current", "animal", "models", "for", "ES", "are", "mostly", "subcutaneously", "injected", "localized", "xenograft", "tumors", "in", "immunodeficient", "mouse", "hosts", "(", "nude", ",", "NOD-SCID", "or", "NSG", ")", "." ] } ]
PMC11633763	All measurements were normalised to the cell number calculated using crystal violet assay at the end of the experiment. *	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "measurements", "were", "normalised", "to", "the", "cell", "number", "calculated", "using", "crystal", "violet", "assay", "at", "the", "end", "of", "the", "experiment", ".", "*" ] } ]
PMC10565698	Fisher's exact test determined the correlation between circUSP10 expression and the clinicopathological parameters.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fisher", "'s", "exact", "test", "determined", "the", "correlation", "between", "circUSP10", "expression", "and", "the", "clinicopathological", "parameters", "." ] } ]
PMC11754432	Mander’s M1 and M2 co-localisation analysis of LAMP1 and EGFR, data are mean per cell per biological replicate (N = 6).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Mander", "’s", "M1", "and", "M2", "co-localisation", "analysis", "of", "LAMP1", "and", "EGFR", ",", "data", "are", "mean", "per", "cell", "per", "biological", "replicate", "(", "N", "=", "6", ")", "." ] } ]
PMC11577421	Uptake of (A) bare NPs and (B) NP_BSA– by CHO-K1 and pgsA-745 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O" ], "tokens": [ "Uptake", "of", "(", "A", ")", "bare", "NPs", "and", "(", "B", ")", "NP_BSA–", "by", "CHO-K1", "and", "pgsA-745", "cells", "." ] } ]
PMC11534377	After dehydration and embedding processes, the samples were sliced into slices with a thickness of 5 μm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "dehydration", "and", "embedding", "processes", ",", "the", "samples", "were", "sliced", "into", "slices", "with", "a", "thickness", "of", "5", "μm", "." ] } ]
PMC4112127	In addition, cells treated with 5-Aza-dC were further treated with 0.5 μM of the histone deacetylase inhibitor trichostatin A for an additional 24 hours.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "addition", ",", "cells", "treated", "with", "5-Aza-dC", "were", "further", "treated", "with", "0.5", "μM", "of", "the", "histone", "deacetylase", "inhibitor", "trichostatin", "A", "for", "an", "additional", "24", "hours", "." ] } ]
PMC11201245	The DNA was digested with the restriction enzymes ALU I and RSA I. The tumor DNA was then labeled with Cy5-dUTP and the reference DNA with Cy3-dUTP (Agilent, Santa Clara, CA, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "DNA", "was", "digested", "with", "the", "restriction", "enzymes", "ALU", "I", "and", "RSA", "I.", "The", "tumor", "DNA", "was", "then", "labeled", "with", "Cy5-dUTP", "and", "the", "reference", "DNA", "with", "Cy3-dUTP", "(", "Agilent", ",", "Santa", "Clara", ",", "CA", ",", "USA", ")", "." ] } ]
PMC9429973	The reason for hospitalization of patients was severe COVID-19 pneumonia and its complications.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "reason", "for", "hospitalization", "of", "patients", "was", "severe", "COVID-19", "pneumonia", "and", "its", "complications", "." ] } ]
PMC11225860	Tumor volume was normalized to the volume at the start of treatment and graphed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Tumor", "volume", "was", "normalized", "to", "the", "volume", "at", "the", "start", "of", "treatment", "and", "graphed", "." ] } ]
PMC9429973	Infections are one of the main reasons for complications and death during active first line treatment, and the rate rises with age.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Infections", "are", "one", "of", "the", "main", "reasons", "for", "complications", "and", "death", "during", "active", "first", "line", "treatment", ",", "and", "the", "rate", "rises", "with", "age", "." ] } ]
PMC11345828	Animals were sacrificed when the tumors reached a size of 1500 mm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Animals", "were", "sacrificed", "when", "the", "tumors", "reached", "a", "size", "of", "1500", "mm", "." ] } ]
PMC9429973	A negative viral load was obtained in 80% of PLHIV.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "negative", "viral", "load", "was", "obtained", "in", "80", "%", "of", "PLHIV", "." ] } ]
PMC11548041	Two hundred-nanosecond MD simulations of the docked poses were performed under normal temperature and pressure conditions using Schrodinger Desmond (Schrödinger Release 2023-3).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Two", "hundred-nanosecond", "MD", "simulations", "of", "the", "docked", "poses", "were", "performed", "under", "normal", "temperature", "and", "pressure", "conditions", "using", "Schrodinger", "Desmond", "(", "Schrödinger", "Release", "2023", "-", "3", ")", "." ] } ]
PMC9429973	Seventeen patients were males, and eleven patients had at least one of the following pre-ECMO comorbidity: ten (43.5%) patients had hypertension, eleven (47.8%) patients had type 2 diabetes and four (17.3%) patients had hyperlipidemia.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Seventeen", "patients", "were", "males", ",", "and", "eleven", "patients", "had", "at", "least", "one", "of", "the", "following", "pre-ECMO", "comorbidity", ":", "ten", "(", "43.5", "%", ")", "patients", "had", "hypertension", ",", "eleven", "(", "47.8", "%", ")", "patients", "had", "type", "2", "diabetes", "and", "four", "(", "17.3", "%", ")", "patients", "had", "hyperlipidemia", "." ] } ]
PMC9429973	Patients with accelerated and acute phases exhibited the unfavorable correlative evolution of CML and COVID-19.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Patients", "with", "accelerated", "and", "acute", "phases", "exhibited", "the", "unfavorable", "correlative", "evolution", "of", "CML", "and", "COVID-19", "." ] } ]
PMC11049548	Unless otherwise specified, all cell culture products were purchased from Euroclone S.p.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Unless", "otherwise", "specified", ",", "all", "cell", "culture", "products", "were", "purchased", "from", "Euroclone", "S.p", "." ] } ]
PMC10565698	F. Agarose electrophoresis assay to verify the loop structure of circUSP10.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "F.", "Agarose", "electrophoresis", "assay", "to", "verify", "the", "loop", "structure", "of", "circUSP10", "." ] } ]
PMC11672881	Different phytochemicals may act on various molecular targets or signaling pathways in cancer progression, providing a comprehensive treatment strategy .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Different", "phytochemicals", "may", "act", "on", "various", "molecular", "targets", "or", "signaling", "pathways", "in", "cancer", "progression", ",", "providing", "a", "comprehensive", "treatment", "strategy", "." ] } ]
PMC11730311	hαCGRP8-37 analogues conjugated with C20DA-γGlu were 2–6 fold more potent than analogues conjugated with C18DA-γGlu at same positions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "hαCGRP8", "-", "37", "analogues", "conjugated", "with", "C20DA-γGlu", "were", "2–6", "fold", "more", "potent", "than", "analogues", "conjugated", "with", "C18DA-γGlu", "at", "same", "positions", "." ] } ]
PMC11423992	Presentation of human IgG1 CH3 domains (PDB entry: 2WAH) and IgG1 CH1-CL domains (PDB entry: 4F33). (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Presentation", "of", "human", "IgG1", "CH3", "domains", "(", "PDB", "entry", ":", "2WAH", ")", "and", "IgG1", "CH1-CL", "domains", "(", "PDB", "entry", ":", "4F33", ")", ".", "(" ] } ]
PMC11683240	Hsp90 (primary antibody from Santa Cruz Biotechnology) was detected as loading control and used to normalize Gαi signal intensity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Hsp90", "(", "primary", "antibody", "from", "Santa", "Cruz", "Biotechnology", ")", "was", "detected", "as", "loading", "control", "and", "used", "to", "normalize", "Gαi", "signal", "intensity", "." ] } ]
PMC11564322	, and ERK1/2 (dilution 1:2000, cat.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ",", "and", "ERK1/2", "(", "dilution", "1:2000", ",", "cat", "." ] } ]
PMC11621493	The radioactivity in cellular MAGs was reduced by 70%.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "radioactivity", "in", "cellular", "MAGs", "was", "reduced", "by", "70", "%", "." ] } ]
PMC11700165	Anti-p-SLP-76 antibody was used for the detection of phosphorylated SLP-76. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Anti-p-SLP-76", "antibody", "was", "used", "for", "the", "detection", "of", "phosphorylated", "SLP-76", ".", "(" ] } ]
PMC11697189	Survival analysis of patients in the high TMB group and low TMB group. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Survival", "analysis", "of", "patients", "in", "the", "high", "TMB", "group", "and", "low", "TMB", "group", ".", "(" ] } ]
PMC11529598	Other studies reported that miR-3154 is associated with acute myeloid leukemia .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Other", "studies", "reported", "that", "miR-3154", "is", "associated", "with", "acute", "myeloid", "leukemia", "." ] } ]
PMC11724582	PrimerForwardReverseYAP5’-ACAGCAGAACCGTTTCCCAGAC-3’5’-GACTTGGCATCAGCTCCTCTCC-3’TAZ5’-CACGCAGGACCTAGACACAGAC-3’5’-CAGGATCTTCTTCCGCCACGAG-3’GAPDH5’-ACAACTTTGGTATCGTGGAAGG-3’5’-GCCATCACGCCACAGTTTC-3’ siRNAs for the knockdown of YAP/TAZ were purchased from GeneChem (Shanghai, China).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "PrimerForwardReverseYAP5’-ACAGCAGAACCGTTTCCCAGAC-3’5’-GACTTGGCATCAGCTCCTCTCC-3’TAZ5’-CACGCAGGACCTAGACACAGAC-3’5’-CAGGATCTTCTTCCGCCACGAG-3’GAPDH5’-ACAACTTTGGTATCGTGGAAGG-3’5’-GCCATCACGCCACAGTTTC-3", "’", "siRNAs", "for", "the", "knockdown", "of", "YAP/TAZ", "were", "purchased", "from", "GeneChem", "(", "Shanghai", ",", "China", ")", "." ] } ]
PMC8073654	The anti-inflammatory activities of the extracts and constituents of Z. cassumunar were investigated in carrageenin-induced edema in rats and acetic acid-induced vascular permeability and writhing symptoms in mice .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "anti-inflammatory", "activities", "of", "the", "extracts", "and", "constituents", "of", "Z.", "cassumunar", "were", "investigated", "in", "carrageenin-induced", "edema", "in", "rats", "and", "acetic", "acid-induced", "vascular", "permeability", "and", "writhing", "symptoms", "in", "mice", "." ] } ]
PMC11574271	A The levels of miR-659-3p were assessed in normal bladder tissues (n = 7) and cancer samples (n = 15) using quantitative real-time polymerase chain reaction (qRT-PCR).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "The", "levels", "of", "miR-659", "-", "3p", "were", "assessed", "in", "normal", "bladder", "tissues", "(", "n", "=", "7", ")", "and", "cancer", "samples", "(", "n", "=", "15", ")", "using", "quantitative", "real-time", "polymerase", "chain", "reaction", "(", "qRT-PCR", ")", "." ] } ]
PMC11592837	A failure to repair DSBs induces the pro-apoptotic p53 upregulated modulator of apoptosis (PUMA) and apoptosis regulator Bcl-2-associated X protein (Bax).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "failure", "to", "repair", "DSBs", "induces", "the", "pro-apoptotic", "p53", "upregulated", "modulator", "of", "apoptosis", "(", "PUMA", ")", "and", "apoptosis", "regulator", "Bcl-2-associated", "X", "protein", "(", "Bax", ")", "." ] } ]
PMC11126803	The results of the UALCAN database showed that patients with higher ESR2 expression had worse survival rates for kidney renal clear cell carcinoma (KIRC) and were independent of sex (Fig. S1A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "results", "of", "the", "UALCAN", "database", "showed", "that", "patients", "with", "higher", "ESR2", "expression", "had", "worse", "survival", "rates", "for", "kidney", "renal", "clear", "cell", "carcinoma", "(", "KIRC", ")", "and", "were", "independent", "of", "sex", "(", "Fig.", "S1A", ")", "." ] } ]
PMC9429973	As previously shown, these effects are linked to MDR1 upregulation in carfilzomib resistant cells and reversible by MDR-1 inhibition.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "As", "previously", "shown", ",", "these", "effects", "are", "linked", "to", "MDR1", "upregulation", "in", "carfilzomib", "resistant", "cells", "and", "reversible", "by", "MDR-1", "inhibition", "." ] } ]

PMC9429973

GATLA is designing a trial with the aim to improve these two different risk groups.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "GATLA", "is", "designing", "a", "trial", "with", "the", "aim", "to", "improve", "these", "two", "different", "risk", "groups", "." ] } ]

PMC11615743

These devices allow for simultaneous analysis of multiple cell surface proteins, achieving greater specificity in cell identification and isolation than D‐DNA‐based logic devices.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "devices", "allow", "for", "simultaneous", "analysis", "of", "multiple", "cell", "surface", "proteins", ",", "achieving", "greater", "specificity", "in", "cell", "identification", "and", "isolation", "than", "D‐DNA‐based", "logic", "devices", "." ] } ]

PMC10213179

After 72 h of aptamer injection, mice were euthanized and ex vivo fluorescence in tumor, heart, liver, kidneys, and spleen was measured.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "72", "h", "of", "aptamer", "injection", ",", "mice", "were", "euthanized", "and", "ex", "vivo", "fluorescence", "in", "tumor", ",", "heart", ",", "liver", ",", "kidneys", ",", "and", "spleen", "was", "measured", "." ] } ]

PMC11786767

Scale bars represent (A) 10 μm; (B and D) whole cells: 5 μm; enlarged segment: 0.5 μm.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bars", "represent", "(", "A", ")", "10", "μm", ";", "(", "B", "and", "D", ")", "whole", "cells", ":", "5", "μm", ";", "enlarged", "segment", ":", "0.5", "μm", "." ] } ]

PMC9429973

Samples were analyzed at each local site according to ICSH guidelines.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Samples", "were", "analyzed", "at", "each", "local", "site", "according", "to", "ICSH", "guidelines", "." ] } ]

PMC11483468

The apoptosis of Hela cells was measured by flow cytometry.

[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "apoptosis", "of", "Hela", "cells", "was", "measured", "by", "flow", "cytometry", "." ] } ]

PMC11474209

Optical biosensors based on QD-FRET are often employed in immunoassays, diagnostic tests, and assessments of biomolecular interaction.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Optical", "biosensors", "based", "on", "QD-FRET", "are", "often", "employed", "in", "immunoassays", ",", "diagnostic", "tests", ",", "and", "assessments", "of", "biomolecular", "interaction", "." ] } ]

PMC11461833

The translation of STXBP5 was evaluated with an anti-STXBP5 antibody, with normalized to -Actin expression. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "translation", "of", "STXBP5", "was", "evaluated", "with", "an", "anti-STXBP5", "antibody", ",", "with", "normalized", "to", "-Actin", "expression", ".", "(" ] } ]

PMC9964635

C NMR (101 MHz, CDCl3) δ 175.22 (C=O), 140.49 (C-1), 137.63 (C-4), 129.04 (C-2 & C-6), 127.31 (C-3 & C-5), 52.09 (OCH3), 44.99 (CH2-9), 40.11 (CH-7), 30.25 (CH-10), 22.21 (CH3-11 & CH3-12), 18.50 (CH3-8).

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PMC9429973

VTE included all symptomatic or incidentally diagnosed cases of pulmonary embolism (PE), deep vein thrombosis (DVT) and thrombosis in unusual sites (cerebral, mesenteric, portal, splenic, hepatic, and renal veins).

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PMC8916024

This provides guidance for future studies on the interaction between the gut flora of snails and their environment.

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PMC10329074

After drawing two horizontal lines on the back of the 12-well plates (Thermo Fisher Scientific, USA), 1.5 × 10 cells either silenced for the YBX3 gene or overexpressing the YBX3 gene were added, according to the experimental design groups.

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PMC11786156

IPI-H cases included five of the 10 available cases, and clinical stage IV cases were five of the 11 available cases.

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PMC11021472

To further understand the growth supporting role of circZDHHC11, we determined whether it could influence gene expression.

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PMC11763126

Fig. 10CBDP1 Inhibits ccRCC Progression In vivo.

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PMC8358006

For IMR90 cell datasets downloaded in BAM format from the ENCODE databases (https://www.encodeproject.org/), the reads were mapped to the human reference genome version hg38.

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PMC11653533

The crude aqueous extract of F. racemosa demonstrated the highest efficacy against the larvae of C. quinquefasciatus and C. gelidus, with LC50 values of 67.72 and 63.70 mg/L, respectively (Velayutham et al., 2013).

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PMC10777969

Additionally, FCP26 with a 2-thiazoline motif linked to the sugar moiety via the nitrogen bridge was studied using single-crystal X-ray crystallography.

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PMC11317131

The remaining single-stranded sequence of the att sites can subsequently be filled in to promote insertion of the full att site (22).

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PMC11515150

In recent years, CAR-NK cells have been a hopeful strategy to avoid fratricide.

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PMC10165258

Second, the PI fluorescent intensity is integrated over this PI mask.

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PMC11740399

Wang et al. reported that the receptor of long-chain free fatty acids (FFAs), G protein-coupled receptor 120 (GPR120), was highly expressed in primary breast cancer treated by chemotherapy.

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PMC10507284

The proliferation, migration, and invasion abilities of the SW982 cells were inhibited with the downregulation of TROAP. (

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PMC11078693

This staining will increase background in the wide-field fluorescence imaging, but not in confocal microscopy.

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PMC11420784

Scale bar, 5 μm.

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PMC11413393

Epiprobes were dissolved in DMSO and added to achieve a final concentration as indicated in Fig. 1a.

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PMC11635519

Notably, PepA3 and its two related variants, PepA and PepA2, stimulated the GLP-1R receptor with lesser potency but the same efficacy as GLP-1.

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PMC9784246

The total methanolic extract, as well as its different fractions, were investigated against lung cancer cell line (A549) using the 3-(4,5-dimethythiazol-2yl)-2,5-diphenyltetrazolium bromide (MTT) cell viability assay method.

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PMC11612315

Interactions between exendin 9–39 and TRPV1 were examined via His-mediated pull-down assays using a modified protocol from the Pierce Pull-down PolyHis Protein:Protein Interaction Kit (Thermo Fisher Scientific).

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PMC10507284

Subsequently, DYRK1 in the cytoplasm activates Akt/GSK‐3β signaling, enhancing the stability and nuclear localization of cyclin D1, thereby accelerating cell cycle progression and facilitating the malignant proliferation of HCC.

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PMC3035438

We described in this report new DT40 strains designed to express chimeric IgG antibodies containing chicken antigen-binding regions and human constant regions of the IgG isoform.

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PMC9436459

Except for compounds 130, 131, and 135, the absolute configurations of C-2 and C-3 of 128, 129, and 132 − 134 have not been determined.

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PMC10452486

While constituting liposomes, they observed the self-association or clustering of fluorescinated Face-2 of HLA-A2.

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PMC9250505

Kaplan–Meier survival analysis was also performed in the EOC patient cohort, which sub-categorized the level of BADS99 as low or high using a receiver operating characteristic curve (Supplementary Fig. 1A, B).

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PMC9436459

Over the past four decades, a total of 166 MDAAs including 150 classic (90%) and 16 non-classic (10%) ones have been described, of which dehydroprenyl-2-arylbenzofuran-, dehydroprenylstilbene-, dehydroprenylchalcone-, dehydroprenylflavone-, dehydroprenyldihydroflavone-, dehydroprenylsanggenonflavone-, dehydroprenylcoumarin-, and simple or other dehydroprenylphenol-types, are the eight subtypes (Types A − H) of the classic MDAAs with the same chalcone-skeleton dienophiles.

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PMC11047729

Moreover, it increases cells’ susceptibility to ATRA, causing ATRA-induced differentiation, cell elimination, and senescence.

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PMC9895440

A donor-paired design matrix an edgeR functions glmQLFit, glmQLFTest, and topTags were used to investigate all significantly dysregulated genes among any conditions (ANOVA-like, Supplementary Data 1) or between each combination of conditions (Supplementary Data 2).

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PMC11585994

T cell activation was conducted using the T Cell TransAct kit (Miltenyi Biotec, 130–111-160) according to the manufacturer’s instructions.

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PMC8270637

TGF-β1-treated/untreated activated T cells were co-cultured with SMMC-7721 cells or cultured separately for 24 h; subsequently, the apoptosis rate of T cells was detected by flow cytometry. (

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PMC11765988

Cigarette smoking is linked to lymphoma formation (NHL and HL) and especially to the follicular form .

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PMC11240448

Interestingly, certain cell lines within this group, such as MDA-MB-157, exhibit notable resistance to MEK inhibitors .

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PMC11122631

For the pharmacokinetics of the compounds, we performed in silico predictions of gastrointestinal absorption, blood–brain barrier permeation, P-glycoprotein substrate, inhibitors for cytochrome P450, and skin permeation (Table S18).

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PMC11706297

This therapy targets the specific oncogenes and signaling pathways that play a critical role in gene expression, apoptosis, and the cell cycle.

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PMC8097906

Briefly, cells were 48 h adapted in assay medium and further treated for 48 h with different concentrations of plant extract (VSM and LW) and plant-derived compounds (Geni, Seco, Mata, Daid and Jaspl.).

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PMC11511922

All data represent one set of triplicates.

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PMC10907726

Next, we further estimated whether autophagy inhibitor 3-MA could reverse the effect of DATS on OS cells growth, migration, invasion and EMT.

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PMC11684269

Furthermore, DKD involves damage to both glomeruli and tubules.

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PMC9429973

Also, we report an association between the progression free survival time and expression level at diagnosis of SERPINA2, RPS26 and UBBP4, suggesting their potential as prognosis biomarkers.

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PMC11361748

One-way ANOVA.

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PMC11600602

The keratinocyte is not an exclusively cutaneous cell type.

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PMC5716223

a Myogenin and b MyHC isoforms expression at different times of differentiation (2, 5, and 9 days post DM) (9 days: NGF MHC Emb: 2.74 ± 0.17 vs Ctrl MHC Emb: 2.19 ± 0.23; NGF MHC IIB: 2.29 ± 0.11 vs Ctrl MHC IIB: 0.98 ± 0.11; p < 0.05 vs 2 and 5 days; *p < 0.05 vs Ctrl 9d.

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PMC6181431

To assess whether these genes were enriched in a pathway that might be consistent with resistance to rapalogs, we performed gene set enrichment analysis using hallmark gene sets .

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PMC11471176

Notwithstanding, meticulous pairwise comparisons between the two compounds demonstrated statistical insignificance across all corresponding concentrations.

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PMC11711063

Specific ECM components associated with cell adhesion and ECM development in myoepithelial cells, including fibronectin‐1, versican, laminins and fibulin2, were induced by ZG16B and downregulated by Bex + Carv in HME‐hTert cells.

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PMC7022782

Once obtained, the purified NP suspension was collected in polyethylene containers and stored at 4 °C.

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PMC10900886

Gating strategy of EV-D68-inoculated immature dendritic cells (imDCs) co-cultured with autologous B-lymphoblastoid cell line (BLCL).

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PMC9429973

Patients with other B-cell non-Hodgkin lymphomas (NHL) who failed standard therapy or, in the opinion of the investigator, have no known available options to provide benefit for the patient’s condition, are also eligible.

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PMC9388315

There was no significant change for 1.25 mg/ml compared to the control group (P > 0.05) (Figure 3(b)).

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PMC11321678

All the qualities described above indicated a good performance of scATAC‐seq in frozen human tissues.

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PMC11699042

We thus observed that the A-673 strains demonstrated a 2- to 3-fold smaller variance compared to the carcinoma cell lines, again highlighting the higher stability of the A-673 strains, even considering the larger sample size in the A-673 collection (Supplementary Fig. 1c).

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PMC9621239

Nonetheless, the underlying mechanism of the different genotypes in the development of HCC remains unknown.

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PMC11680562

The gel was made by adjusting the xanthan gum concentration to assess the sustainable release of the drug.

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PMC9096373

Cell growth was observed daily using phase-contrast microscopy and the medium was changed every 2 days.

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PMC11687663

Strategies to improve its bioavailability and permeability, such as chemical modifications or advanced drug delivery systems, could unlock its potential.

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PMC5810978

Current culture systems (BJAB cells or primary human stem cell-derived enteroids) for HuNoVs support modest virus replication.

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PMC11477621

Compound 5h was prepared using similar procedures as for 3a from compound 4h (296 mg, 1.02 mmol).

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PMC9672323

The graphs show the mean ± SD.

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PMC10587429

Current animal models for ES are mostly subcutaneously injected localized xenograft tumors in immunodeficient mouse hosts (nude, NOD-SCID or NSG).

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PMC11633763

All measurements were normalised to the cell number calculated using crystal violet assay at the end of the experiment. *

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PMC10565698

Fisher's exact test determined the correlation between circUSP10 expression and the clinicopathological parameters.

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PMC11754432

Mander’s M1 and M2 co-localisation analysis of LAMP1 and EGFR, data are mean per cell per biological replicate (N = 6).

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PMC11577421

Uptake of (A) bare NPs and (B) NP_BSA– by CHO-K1 and pgsA-745 cells.

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PMC11534377

After dehydration and embedding processes, the samples were sliced into slices with a thickness of 5 μm.

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PMC4112127

In addition, cells treated with 5-Aza-dC were further treated with 0.5 μM of the histone deacetylase inhibitor trichostatin A for an additional 24 hours.

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PMC11201245

The DNA was digested with the restriction enzymes ALU I and RSA I. The tumor DNA was then labeled with Cy5-dUTP and the reference DNA with Cy3-dUTP (Agilent, Santa Clara, CA, USA).

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PMC9429973

The reason for hospitalization of patients was severe COVID-19 pneumonia and its complications.

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PMC11225860

Tumor volume was normalized to the volume at the start of treatment and graphed.

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PMC9429973

Infections are one of the main reasons for complications and death during active first line treatment, and the rate rises with age.

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PMC11345828

Animals were sacrificed when the tumors reached a size of 1500 mm.

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PMC9429973

A negative viral load was obtained in 80% of PLHIV.

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PMC11548041

Two hundred-nanosecond MD simulations of the docked poses were performed under normal temperature and pressure conditions using Schrodinger Desmond (Schrödinger Release 2023-3).

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PMC9429973

Seventeen patients were males, and eleven patients had at least one of the following pre-ECMO comorbidity: ten (43.5%) patients had hypertension, eleven (47.8%) patients had type 2 diabetes and four (17.3%) patients had hyperlipidemia.

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PMC9429973

Patients with accelerated and acute phases exhibited the unfavorable correlative evolution of CML and COVID-19.

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PMC11049548

Unless otherwise specified, all cell culture products were purchased from Euroclone S.p.

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PMC10565698

F. Agarose electrophoresis assay to verify the loop structure of circUSP10.

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PMC11672881

Different phytochemicals may act on various molecular targets or signaling pathways in cancer progression, providing a comprehensive treatment strategy .

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PMC11730311

hαCGRP8-37 analogues conjugated with C20DA-γGlu were 2–6 fold more potent than analogues conjugated with C18DA-γGlu at same positions.

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PMC11423992

Presentation of human IgG1 CH3 domains (PDB entry: 2WAH) and IgG1 CH1-CL domains (PDB entry: 4F33). (

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PMC11683240

Hsp90 (primary antibody from Santa Cruz Biotechnology) was detected as loading control and used to normalize Gαi signal intensity.

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PMC11564322

, and ERK1/2 (dilution 1:2000, cat.

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PMC11621493

The radioactivity in cellular MAGs was reduced by 70%.

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PMC11700165

Anti-p-SLP-76 antibody was used for the detection of phosphorylated SLP-76. (

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PMC11697189

Survival analysis of patients in the high TMB group and low TMB group. (

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PMC11529598

Other studies reported that miR-3154 is associated with acute myeloid leukemia .

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PMC11724582

PrimerForwardReverseYAP5’-ACAGCAGAACCGTTTCCCAGAC-3’5’-GACTTGGCATCAGCTCCTCTCC-3’TAZ5’-CACGCAGGACCTAGACACAGAC-3’5’-CAGGATCTTCTTCCGCCACGAG-3’GAPDH5’-ACAACTTTGGTATCGTGGAAGG-3’5’-GCCATCACGCCACAGTTTC-3’ siRNAs for the knockdown of YAP/TAZ were purchased from GeneChem (Shanghai, China).

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PMC8073654

The anti-inflammatory activities of the extracts and constituents of Z. cassumunar were investigated in carrageenin-induced edema in rats and acetic acid-induced vascular permeability and writhing symptoms in mice .

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PMC11574271

A The levels of miR-659-3p were assessed in normal bladder tissues (n = 7) and cancer samples (n = 15) using quantitative real-time polymerase chain reaction (qRT-PCR).

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PMC11592837

A failure to repair DSBs induces the pro-apoptotic p53 upregulated modulator of apoptosis (PUMA) and apoptosis regulator Bcl-2-associated X protein (Bax).

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PMC11126803

The results of the UALCAN database showed that patients with higher ESR2 expression had worse survival rates for kidney renal clear cell carcinoma (KIRC) and were independent of sex (Fig. S1A).

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PMC9429973

As previously shown, these effects are linked to MDR1 upregulation in carfilzomib resistant cells and reversible by MDR-1 inhibition.

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