OTAR3088/BioData-CellLine_annotated · Datasets at Hugging Face

PMCID string	Sentences string	ner list
PMC8345486	Unmodified adenosine (Ade), or 2′-deoxyadenosine (dAde), and metalla bis(dicarbollide) modifying units itself (compounds 1–3) were reference compounds in relation to the presence of the nucleoside or metalla bis(dicarbollide) unit:3-cobalt-bis(1,2-dicarba-closo-undecaborate](−1) (3) (1),3-ferra-bis(1,2-dicarba-closo-undecaborate](−1) (2),3-chromma-bis(1,2-dicarba-closo-undecaborate](−1) (3).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11779605	The Compass program for Simple Western (Bio-Techne, Minneapolis, MN, USA) was used for initial analysis; peaks were chosen based on the molecular weight markers.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10158546	In contrast to immortalized cell cultures, primary neuronal cultures can be used in the study of acute prion toxicity but do not have the longevity required for prion replication .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11707577	Flow cytometry results expressed as H) histogram of fluorescence peaks, I) mean fluorescence intensity (MFI), J) percentage of fluorescent events.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8336407	The results showed a decrease in nitrite production in t100/E1.5 treated group (40 ± 2.63 µM) and t100/E2.0 mg/mL treated group (43.7 ± 2.80 µM) (p < 0.001) (Table 2).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11352311	These findings indicated that esculin treatment reduces the proliferation of RCC cells compared to the control group.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "findings", "indicated", "that", "esculin...
PMC11786704	This study developed a simple and highly efficient method for preparing proanthocyanidin (PC) capsules through hydrogen bonding and hydrophobic interactions among PC molecules.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973	Aims: To assess the efficacy of different nMoAbs approved by Agenzia Italiana del Farmaco (AIFA) on HM patients affected by paucisymptomatic SARS-COV-2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9351137	Fluorescence intensity was assessed using the ImageJ software and statistical significance was verified by T- test.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fluorescence", "intensity", "was", "assessed", "using", ...
PMC10253973	The enormous speed of molecular docking allows huge libraries of small molecules to be searched at low cost to identify potential drug candidates; the procedure, called virtual screening (VS), has become an elementary step in modern drug design .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11265931	All cell lines that were seeded with 1 × 105cell/well onto a 6-well plate were treated with 60 μg/mL of garlic SEVs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "cell"...
PMC9429973	Summary/Conclusion: The number of polyclonal plasma cells and mast cells in the bone marrow sample could be useful in predicting myeloma progression in patients with a MRD (-) bone marrow assessment by NGF.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11473750	Genomic coordinates are provided in megabase measurements (Mb) below the plot.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Genomic", "coordinates", "are", "provided", "in", "megabase", "measurements", ...
PMC11629192	The long treatment intervals of Ocrelizumab can reduce the need for frequent injections.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "long", "treatment", "intervals", "of", "Ocrelizumab", "can", "reduce...
PMC7215722	Noteworthy, alterations in the trafficking behavior and membrane lipid composition in DSS-treated cells are closely linked to the increased expression of ATF4 and CHOP, which are, in turn, activators of the pro-inflammatory cytokine TNF-α , which is directly implicated in the pathogenesis of IBD.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11352311	The cells were then washed and lysed, and 50 μL of 2-DG Uptake Assay working solution was added to each well.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cells...
PMC8873393	Differentially expressed transcripts have been identified on these transformed values by using the criteria of log2 (Fold Change) ≥ 1 and padj < 0.05.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC10344560	Based on the high clinical suspicion of fungal peritonitis, fluconazole intraperitoneal (IP) was immediately given on the first day of treatment in addition to empirical antibiotics that is cefazolin and gentamycin IP.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11155445	Nickel complexes crystallized in a non-centrosymmetric system adopting the P21 space group while other complexes crystallized in a centrosymmetric system having a P1̄ space group.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973	For subjects aged 1 to <2 yrs, the proposed doses shown in the Table are predicted to provide <5% difference in mitapivat AUC as compared with adults.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10936243	All 49 respondents were aware of, and acknowledged, the importance of freedom from pain and discomfort in cats.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "49", "respondents", ...
PMC11240448	After we built the two separating, maximal margin hyperplanes, we constructed the two unit vectors that are normal to these two separating hyperplanes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10919056	This study has certain limitations.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "study", "has", "certain", "limitations", "." ] } ]
PMC11704834	A total of 24 h post-transfection, transfected cells were treated with 1 µg/ml puromycin (Invitrogen; Thermo Fisher Scientific, Inc.) to select for stable clones.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11380329	Nowadays, scientists are interested by natural products which have risen to the forefront of drug discovery.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Nowadays", ",", "scientists", "are", "interested"...
PMC11139449	Cas9 cleaves both the target site and the donor vector, integrating the DNA template through NHEJ.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cas9", "cleaves", "both", "the", "target", ...
PMC11319300	This is similar to the interaction observed in humans and, interestingly, coincides with CTCF binding sites in both species.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "is", "sim...
PMC6600253	Chung et al. indicated that RSV enhanced the antitelomeric activities of 5-FU by inhibiting Stat3 binding to the hTERT promoter region .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Chung", "et", "al...
PMC11656380	Tat-Ram13 presents a promising alternative by targeting malignant cells while minimizing normal tissue toxicity, thus crucially reducing adverse effects.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Tat-Ram13", "presents", "a",...
PMC11371627	Gait testing revealed Trendelenburg sign on the right side and walking on tiptoes and heels was impeded.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Gait", "testing", "revealed", "Trendelenburg", "s...
PMC11727062	Kaempferols also restrict the activity of pyruvate kinase, a key enzyme in glycolysis, culminating in the inhibition of cell proliferation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Kaempferols", ...
PMC10858941	A p62 immunofluorescence in microfluidic devices seeded with U-251 MG and A-172.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "O", "B-CellLine", "O" ], "tokens": [ "A", "p62", "immunofluorescence", "in", "microfluidic", "devices", ...
PMC11590870	For example, they are easier to obtain, exert low-toxicity or non-toxic effects, and have built-in chirality, which is difficult to achieve when synthesizing molecules .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6461034	Kinases with a top 20 INKA score for models CRC0177 or CRC0254 are indicated by matching colors as in panel A (coral: BMS‐754807, blue: afatinib, green: imatinib).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11119602	This is in line with the observation that resistance to the anti-cancer drug doxorubicin in breast cancer cells seems to be dependent upon the action of TG2 on ECM proteins, thereby promoting the interaction between integrins and fibronectin .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Patients with LVEF >50% had echocardiographic signs of cardiac morbidity like severe heart valve disease, history of significant cardiac impairment or prior treatment with anthracyclines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9352806	Three independent experiments were performed.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Three", "independent", "experiments", "were", "performed", "." ] } ]
PMC11342785	E, example image showing a recently divided cell where a bundled MT-architecture has reformed at the site of separation, indicating synMAP structures are compatible with mitosis and cell division.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10421378	The viability and activity of probiotic bacteria cells in the samples were determined by performing fluorescent staining with RedoxSensorTM Green and PI (propidium iodide).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11621493	The parallel increase in various LPC and LPE species in PLA2G4D-expressing cells suggests that PC/PE act as donor lipids.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "parallel", "increase", "in...
PMC11687663	This significant binding affinity and stable ligand-receptor complex suggests a high potential for pharmacological efficacy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "significant", "binding", "affinity", "and", "stable", ...
PMC11679892	In our study, measurements performed with ELISA revealed that P. sidoides affects DNA damage and is an important indicator of oxidative stress by increasing 8-Hydroxy-deoxyguanosine levels.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11676670	High-grade serous ovarian cancer (HGSOC) is the most frequent subtype, accounting for 68–75% of all epithelial ovarian cancer (EOC) cases .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11707832	Notably, MAN2B1 exhibits elevated expression in monocytes and dendritic cells, pivotal in the body’s immune defence against infections and inflammatory responses.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973	Methods: Aliquots of whole blood or isolated peripheral blood mononuclear cells (PBMC) from healthy volunteer donors underwent T cell activation with CD3/CD28 beads and incubation with or without a selective CTPS1 inhibitor for 24-72 hours.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11655536	To further investigate the changes of internal organelles in HA-treated cells, we fixed the cells and observed the alteration of organelles including lysosome with transmission electron microscopy (TEM).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10976516	Lung tumor carrier cells end up preferentially in the lung while leukemic carrier cells disperse systemically.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Lung", "tumor", "carrier", "cells", "end", "up", ...
PMC4839679	Fresh media was added to the cells and ten designated points on the scratch were imaged at 0h.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fresh", "media", "was", "added", "to",...
PMC11470381	Images were acquired at 63×/1.4 magnification.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Images", "were", "acquired", "at", "63", "×", "/1.4", "magnification", "." ] } ]
PMC10850553	Scale bar: 50 μm. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bar", ":", "50", "μm", ".", "(" ] } ]
PMC11049548	The same trend is also present in HGSOC_T and HGSOC_A, although with a markedly less pronounced trend (average log2(FC) = 2.25 and 2.86 for PC and 0.63 and 0.43 for GPC, in HGSOC_T and HGSOC_A, respectively) (Figure 3C and Figure 5).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11334037	After 1 d, we added CCK-8 reagent (10 μL, Catalog No. AD10; Dojindo Molecular Technologies, Kumamoto, Japan) to each well at room temperature.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7039683	The trained classifier can subsequently be used to score any element for its similarity to the training set, and also to evaluate the effect of a SNP on the score of the element containing it.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9024365	However, in contrast to SD4, we observed clustering when the GluK2/A2/M4/CT chimera was co-expressed with SD1 (Figure 5B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",...
PMC10994876	These improvements encompassed cell growth, proliferation, viability, and productivity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "improvements", "encompassed", "cell", "growth", ",", "proliferation", ",", ...
PMC8557138	Many studies have attempted to mimic the angiogenic tumor microenvironment using microfluidic devices.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Many", "studies", "have", "attempted", "to", "mimic", "the", "angiogenic", ...
PMC9878562	Cumulative data from five different experiments measured in triplicates (means ± SD, unpaired t-test, ****p ≤ 0.0001). (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC4355729	PI3K is activated through attachment to receptors anchored on plasma membrane and generates phosphatidylinositol-3-phosphate (PIP3) by phosphorylating phosphatidylinositol 4, 5-bisphosphate8.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9712534	Average values with SD were calculated from 5 independent experiments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Average", "values", "with", "SD", "were", "calculated", "from", "5", "independent", "experiments...
PMC9780037	In a fluorescent biosensor, a cyt c aptamer is adsorbed on a nanosheet, quenching its fluorescence.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "a", "fluorescent", "biosensor", ...
PMC11473843	3422, Corning).	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "3422", ",", "Corning", ")", "." ] } ]
PMC11650848	Significant p value: p < 0.05 tested via ANCOVA, confounding for sex Cognitive and MEG analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Significant", "p", "value", ":", "p", ...
PMC9429973	A median number of 70.5-139.6 dialyses per pt per year were received by 70 (13.2%) pts, across cardiac stages.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973	The action of HFE in the pathogenesis of SMA and its role on the immune response activation, elicited to combat malaria, was also investigated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11380329	A recent study shows that artepillin C potently sensitized the resistant prostate cancer cells to treatment by inducing apoptotic cell death due to mitochondrial dysfunction .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11218145	Western blot analysis of the protein expression induced by TB (1 μM) at 24 h (for ERK 1/2 and p38) or 48 h (for BAX) post- treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8481254	D The protein expression of OGT, O-GlcNAc, YAP, and CDK19 in Bel-7402 and Bel-7404 cells was measured by WB.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O" ], "tokens": [ "...
PMC9429973	Clinical and biological characteristics at diagnosis were reported.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Clinical", "and", "biological", "characteristics", "at", "diagnosis", "were", "reported", "." ] } ]
PMC10847511	Gene expression and methylation beta values of the BRCA1 promoter regions were analyzed to annotate methylation silencing for each cell line.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Gene", "expression", ...
PMC11290772	Additionally, unlike T cells that freely expand within the host, the lifespan of CAR-NK cells is restricted, providing an additional level of control over the quantity of donor cells within the host .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10969097	After searching the same databases with additional terms as previously described in Section 2.1 of this paper, we obtained a result of 8 clinical trials in the Clinicaltrial.com database and 38 in ICTRP.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11244823	Subsequently, the cells were washed twice with 12mL Opti-MEM and then incubated with 20mL of fresh DMEM for another 48h at 37°C and 5% CO2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11634027	The ICD, transmembrane domain, and part of the extracellular domain are encoded by a single exon (exon 12) (Fig. 1A, Fig. S2A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11247842	Using all these results, putative causal genes and variants were called.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Using", "all", "these", "results", ",", "putative", "causal", "genes", "and", ...
PMC11765988	However, the reverse phenomenon has also been described.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "the", "reverse", "phenomenon", "has", "also", "been", "described", "." ] } ]
PMC11438317	The hemagglutinin (HA) monoclonal antibody (mAb) was from Covance (Berkely, CA USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "hemagglutinin", "(", "HA",...
PMC6190245	Cell survival was quantitated by MTT assay.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cell", "survival", "was", "quantitated", "by", "MTT", "assay", "." ] } ]
PMC8584319	However, treatment with AZD8055 for a short period activated both ERK1/2 and p38 in HepG2 cells (Figure 3a).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",",...
PMC11743316	Tumor growth and stemness may be supported by the fusion and fission dynamics of mitochondria, which carry out mitophagy to eliminate damaged mitochondria.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC6163708	We have previously tested melanoma cells and found that GANT61 was variably effective in all tumors.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "have", "previously", "tested", "melanoma", "cell...
PMC11478724	The highest caspase 3 activity was observed 72 h after PMX treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "highest", "caspase", "3", "activity", "was", "observed", "72", "h", ...
PMC11637284	Similar to what was observed for TAC60, AlphaFold2 and helical wheel analyzes suggest that the C-terminal 12 aa of T. brucei p166 fold into a short α-helix, the amphiphilic nature of which is conserved in all Kinetoplastids (Fig 3C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11656048	The data were presented as mean ± SD, and analyzed using one-way ANOVA following Tukey’s t-test (n = 3).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...
PMC11507371	In addition, all melting curves generated were analysed individually to validate the absence of unspecific products.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "addition", ",", "all", "melting", "cu...
PMC8469018	On the representative scatter plots, it can be observed that teriflunomide did not reduce the VB48 intensity in cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "On", "the", "representative"...
PMC11173119	Familial Mediterranean fever (FMF) is a systemic autoinflammatory disorder characterized by recurrent episodes of fever and polyserositis (e.g., peritonitis, pleuritis, synovitis) symptoms.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11462673	Following a 30-min incubation at 4 °C in a refrigerated centrifuge, the lysate was centrifuged to obtain the supernatant for collection.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Followi...
PMC9429973	Finally, we found that allergic patients had a lower proportion of public clonotypes (i.e. public clonotypic sequences found on VDJDB database) compared to non-allergic patients (P=0.02, Figure 1I), supporting the “hygiene hypothesis” as a predisposing factor in development of allergy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11657744	For knockdown experiments, NIH3T3 cells were plated and transfected with either a negative control siRNA (Invitrogen) or targeting siRNA to deplete the target genes for 24 hours.	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6487404	The volume of the buffer on the apical and basolateral side of the cell layer was 0.3 mL and 0.7 mL, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...
PMC9727330	Flow cytometry fractionation quantifies the kinetic profile of ASNS protein expression in Caco-2 cells treated with 4 mg/ml of each amino acid compared to DMSO treated cells LDH Production in Treated Cancer Cells (Caco-2 Cells) NT, Untreated cells (Control) Levels of Produced Inflammatory Interleukins in Treated Cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Recent small series of clinical experience suggest the incidence to be about 10% at baseline and 30% at first relapse.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Recent", "sm...
PMC9000591	The most abundant group was isoflavones with six detected compounds, followed by triterpenes with three identified compounds.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "most", "abundant", "group", "wa...
PMC11144382	The 5 MSS NFIX frameshift mutations in exons 6-8 comprised 3 deletions (c.819-732_1079-948del, c.819-471_1079-687del, c.819-592_1079-808del), an insertion (c.1037_1038insT), and a duplication (c.1090dupG).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11107915	Its ability to process and generate human-like text makes it a valuable tool in the healthcare ecosystem, particularly in fields where effective communication is crucial.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11345828	LCMS Method 1: RT = 2.159, 2.193 min, MS (ESI): mass calcd for C41H43Cl2N5O5, 755.3, m/z found, 755.8 (M + H).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8481254	We found that, compared to 5.5 mM glucose, 25 mM glucose had no effect on LATS1, LATS2, MST1, or MST2 (Fig. 2C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11468365	The work in TranSynergy proposed a method that depends on the cellular effect of drug actions which can be modeled by gene dependencies and gene–gene interactions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11400680	The proposed instance segmentation model is designed and validated using a large public dataset called EVICAN and achieved a favorable performance showing average mAP50 scores of 96.25, 95.05, and 94.18 for cell segmentation, and 68.04, 54.66, and 38.29 for nucleus segmentation on easy, medium, and different test sets of EVICAN, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	MM is most frequently diagnosed among people >65 years of age and the median age at onset in Europe is 72 years.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "MM", ...

PMC8345486

Unmodified adenosine (Ade), or 2′-deoxyadenosine (dAde), and metalla bis(dicarbollide) modifying units itself (compounds 1–3) were reference compounds in relation to the presence of the nucleoside or metalla bis(dicarbollide) unit:3-cobalt-bis(1,2-dicarba-closo-undecaborate](−1) (3) (1),3-ferra-bis(1,2-dicarba-closo-undecaborate](−1) (2),3-chromma-bis(1,2-dicarba-closo-undecaborate](−1) (3).

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PMC11779605

The Compass program for Simple Western (Bio-Techne, Minneapolis, MN, USA) was used for initial analysis; peaks were chosen based on the molecular weight markers.

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PMC10158546

In contrast to immortalized cell cultures, primary neuronal cultures can be used in the study of acute prion toxicity but do not have the longevity required for prion replication .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11707577

Flow cytometry results expressed as H) histogram of fluorescence peaks, I) mean fluorescence intensity (MFI), J) percentage of fluorescent events.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8336407

The results showed a decrease in nitrite production in t100/E1.5 treated group (40 ± 2.63 µM) and t100/E2.0 mg/mL treated group (43.7 ± 2.80 µM) (p < 0.001) (Table 2).

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PMC11352311

These findings indicated that esculin treatment reduces the proliferation of RCC cells compared to the control group.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "findings", "indicated", "that", "esculin...

PMC11786704

This study developed a simple and highly efficient method for preparing proanthocyanidin (PC) capsules through hydrogen bonding and hydrophobic interactions among PC molecules.

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PMC9429973

Aims: To assess the efficacy of different nMoAbs approved by Agenzia Italiana del Farmaco (AIFA) on HM patients affected by paucisymptomatic SARS-COV-2.

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PMC9351137

Fluorescence intensity was assessed using the ImageJ software and statistical significance was verified by T- test.

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PMC10253973

The enormous speed of molecular docking allows huge libraries of small molecules to be searched at low cost to identify potential drug candidates; the procedure, called virtual screening (VS), has become an elementary step in modern drug design .

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PMC11265931

All cell lines that were seeded with 1 × 105cell/well onto a 6-well plate were treated with 60 μg/mL of garlic SEVs.

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PMC9429973

Summary/Conclusion: The number of polyclonal plasma cells and mast cells in the bone marrow sample could be useful in predicting myeloma progression in patients with a MRD (-) bone marrow assessment by NGF.

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PMC11473750

Genomic coordinates are provided in megabase measurements (Mb) below the plot.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Genomic", "coordinates", "are", "provided", "in", "megabase", "measurements", ...

PMC11629192

The long treatment intervals of Ocrelizumab can reduce the need for frequent injections.

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PMC7215722

Noteworthy, alterations in the trafficking behavior and membrane lipid composition in DSS-treated cells are closely linked to the increased expression of ATF4 and CHOP, which are, in turn, activators of the pro-inflammatory cytokine TNF-α , which is directly implicated in the pathogenesis of IBD.

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PMC11352311

The cells were then washed and lysed, and 50 μL of 2-DG Uptake Assay working solution was added to each well.

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PMC8873393

Differentially expressed transcripts have been identified on these transformed values by using the criteria of log2 (Fold Change) ≥ 1 and padj < 0.05.

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PMC10344560

Based on the high clinical suspicion of fungal peritonitis, fluconazole intraperitoneal (IP) was immediately given on the first day of treatment in addition to empirical antibiotics that is cefazolin and gentamycin IP.

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PMC11155445

Nickel complexes crystallized in a non-centrosymmetric system adopting the P21 space group while other complexes crystallized in a centrosymmetric system having a P1̄ space group.

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PMC9429973

For subjects aged 1 to <2 yrs, the proposed doses shown in the Table are predicted to provide <5% difference in mitapivat AUC as compared with adults.

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PMC10936243

All 49 respondents were aware of, and acknowledged, the importance of freedom from pain and discomfort in cats.

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PMC11240448

After we built the two separating, maximal margin hyperplanes, we constructed the two unit vectors that are normal to these two separating hyperplanes.

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PMC10919056

This study has certain limitations.

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PMC11704834

A total of 24 h post-transfection, transfected cells were treated with 1 µg/ml puromycin (Invitrogen; Thermo Fisher Scientific, Inc.) to select for stable clones.

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PMC11380329

Nowadays, scientists are interested by natural products which have risen to the forefront of drug discovery.

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PMC11139449

Cas9 cleaves both the target site and the donor vector, integrating the DNA template through NHEJ.

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PMC11319300

This is similar to the interaction observed in humans and, interestingly, coincides with CTCF binding sites in both species.

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PMC6600253

Chung et al. indicated that RSV enhanced the antitelomeric activities of 5-FU by inhibiting Stat3 binding to the hTERT promoter region .

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PMC11656380

Tat-Ram13 presents a promising alternative by targeting malignant cells while minimizing normal tissue toxicity, thus crucially reducing adverse effects.

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PMC11371627

Gait testing revealed Trendelenburg sign on the right side and walking on tiptoes and heels was impeded.

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PMC11727062

Kaempferols also restrict the activity of pyruvate kinase, a key enzyme in glycolysis, culminating in the inhibition of cell proliferation.

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PMC10858941

A p62 immunofluorescence in microfluidic devices seeded with U-251 MG and A-172.

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PMC11590870

For example, they are easier to obtain, exert low-toxicity or non-toxic effects, and have built-in chirality, which is difficult to achieve when synthesizing molecules .

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PMC6461034

Kinases with a top 20 INKA score for models CRC0177 or CRC0254 are indicated by matching colors as in panel A (coral: BMS‐754807, blue: afatinib, green: imatinib).

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PMC11119602

This is in line with the observation that resistance to the anti-cancer drug doxorubicin in breast cancer cells seems to be dependent upon the action of TG2 on ECM proteins, thereby promoting the interaction between integrins and fibronectin .

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PMC9429973

Patients with LVEF >50% had echocardiographic signs of cardiac morbidity like severe heart valve disease, history of significant cardiac impairment or prior treatment with anthracyclines.

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PMC9352806

Three independent experiments were performed.

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PMC11342785

E, example image showing a recently divided cell where a bundled MT-architecture has reformed at the site of separation, indicating synMAP structures are compatible with mitosis and cell division.

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PMC10421378

The viability and activity of probiotic bacteria cells in the samples were determined by performing fluorescent staining with RedoxSensorTM Green and PI (propidium iodide).

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PMC11621493

The parallel increase in various LPC and LPE species in PLA2G4D-expressing cells suggests that PC/PE act as donor lipids.

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PMC11687663

This significant binding affinity and stable ligand-receptor complex suggests a high potential for pharmacological efficacy.

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PMC11679892

In our study, measurements performed with ELISA revealed that P. sidoides affects DNA damage and is an important indicator of oxidative stress by increasing 8-Hydroxy-deoxyguanosine levels.

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PMC11676670

High-grade serous ovarian cancer (HGSOC) is the most frequent subtype, accounting for 68–75% of all epithelial ovarian cancer (EOC) cases .

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PMC11707832

Notably, MAN2B1 exhibits elevated expression in monocytes and dendritic cells, pivotal in the body’s immune defence against infections and inflammatory responses.

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PMC9429973

Methods: Aliquots of whole blood or isolated peripheral blood mononuclear cells (PBMC) from healthy volunteer donors underwent T cell activation with CD3/CD28 beads and incubation with or without a selective CTPS1 inhibitor for 24-72 hours.

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PMC11655536

To further investigate the changes of internal organelles in HA-treated cells, we fixed the cells and observed the alteration of organelles including lysosome with transmission electron microscopy (TEM).

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PMC10976516

Lung tumor carrier cells end up preferentially in the lung while leukemic carrier cells disperse systemically.

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PMC4839679

Fresh media was added to the cells and ten designated points on the scratch were imaged at 0h.

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PMC11470381

Images were acquired at 63×/1.4 magnification.

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PMC10850553

Scale bar: 50 μm. (

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PMC11049548

The same trend is also present in HGSOC_T and HGSOC_A, although with a markedly less pronounced trend (average log2(FC) = 2.25 and 2.86 for PC and 0.63 and 0.43 for GPC, in HGSOC_T and HGSOC_A, respectively) (Figure 3C and Figure 5).

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PMC11334037

After 1 d, we added CCK-8 reagent (10 μL, Catalog No. AD10; Dojindo Molecular Technologies, Kumamoto, Japan) to each well at room temperature.

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PMC7039683

The trained classifier can subsequently be used to score any element for its similarity to the training set, and also to evaluate the effect of a SNP on the score of the element containing it.

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PMC9024365

However, in contrast to SD4, we observed clustering when the GluK2/A2/M4/CT chimera was co-expressed with SD1 (Figure 5B).

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PMC10994876

These improvements encompassed cell growth, proliferation, viability, and productivity.

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PMC8557138

Many studies have attempted to mimic the angiogenic tumor microenvironment using microfluidic devices.

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PMC9878562

Cumulative data from five different experiments measured in triplicates (means ± SD, unpaired t-test, ****p ≤ 0.0001). (

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PMC4355729

PI3K is activated through attachment to receptors anchored on plasma membrane and generates phosphatidylinositol-3-phosphate (PIP3) by phosphorylating phosphatidylinositol 4, 5-bisphosphate8.

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PMC9712534

Average values with SD were calculated from 5 independent experiments.

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PMC9780037

In a fluorescent biosensor, a cyt c aptamer is adsorbed on a nanosheet, quenching its fluorescence.

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PMC11473843

3422, Corning).

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PMC11650848

Significant p value: p < 0.05 tested via ANCOVA, confounding for sex Cognitive and MEG analysis.

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PMC9429973

A median number of 70.5-139.6 dialyses per pt per year were received by 70 (13.2%) pts, across cardiac stages.

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PMC9429973

The action of HFE in the pathogenesis of SMA and its role on the immune response activation, elicited to combat malaria, was also investigated.

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PMC11380329

A recent study shows that artepillin C potently sensitized the resistant prostate cancer cells to treatment by inducing apoptotic cell death due to mitochondrial dysfunction .

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PMC11218145

Western blot analysis of the protein expression induced by TB (1 μM) at 24 h (for ERK 1/2 and p38) or 48 h (for BAX) post- treatment.

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PMC8481254

D The protein expression of OGT, O-GlcNAc, YAP, and CDK19 in Bel-7402 and Bel-7404 cells was measured by WB.

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PMC9429973

Clinical and biological characteristics at diagnosis were reported.

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PMC10847511

Gene expression and methylation beta values of the BRCA1 promoter regions were analyzed to annotate methylation silencing for each cell line.

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PMC11290772

Additionally, unlike T cells that freely expand within the host, the lifespan of CAR-NK cells is restricted, providing an additional level of control over the quantity of donor cells within the host .

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PMC10969097

After searching the same databases with additional terms as previously described in Section 2.1 of this paper, we obtained a result of 8 clinical trials in the Clinicaltrial.com database and 38 in ICTRP.

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PMC11244823

Subsequently, the cells were washed twice with 12mL Opti-MEM and then incubated with 20mL of fresh DMEM for another 48h at 37°C and 5% CO2.

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PMC11634027

The ICD, transmembrane domain, and part of the extracellular domain are encoded by a single exon (exon 12) (Fig. 1A, Fig. S2A).

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PMC11247842

Using all these results, putative causal genes and variants were called.

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PMC11765988

However, the reverse phenomenon has also been described.

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PMC11438317

The hemagglutinin (HA) monoclonal antibody (mAb) was from Covance (Berkely, CA USA).

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PMC6190245

Cell survival was quantitated by MTT assay.

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PMC8584319

However, treatment with AZD8055 for a short period activated both ERK1/2 and p38 in HepG2 cells (Figure 3a).

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PMC11743316

Tumor growth and stemness may be supported by the fusion and fission dynamics of mitochondria, which carry out mitophagy to eliminate damaged mitochondria.

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PMC6163708

We have previously tested melanoma cells and found that GANT61 was variably effective in all tumors.

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PMC11478724

The highest caspase 3 activity was observed 72 h after PMX treatment.

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PMC11637284

Similar to what was observed for TAC60, AlphaFold2 and helical wheel analyzes suggest that the C-terminal 12 aa of T. brucei p166 fold into a short α-helix, the amphiphilic nature of which is conserved in all Kinetoplastids (Fig 3C).

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PMC11656048

The data were presented as mean ± SD, and analyzed using one-way ANOVA following Tukey’s t-test (n = 3).

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PMC11507371

In addition, all melting curves generated were analysed individually to validate the absence of unspecific products.

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PMC8469018

On the representative scatter plots, it can be observed that teriflunomide did not reduce the VB48 intensity in cells.

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PMC11173119

Familial Mediterranean fever (FMF) is a systemic autoinflammatory disorder characterized by recurrent episodes of fever and polyserositis (e.g., peritonitis, pleuritis, synovitis) symptoms.

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PMC11462673

Following a 30-min incubation at 4 °C in a refrigerated centrifuge, the lysate was centrifuged to obtain the supernatant for collection.

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PMC9429973

Finally, we found that allergic patients had a lower proportion of public clonotypes (i.e. public clonotypic sequences found on VDJDB database) compared to non-allergic patients (P=0.02, Figure 1I), supporting the “hygiene hypothesis” as a predisposing factor in development of allergy.

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PMC11657744

For knockdown experiments, NIH3T3 cells were plated and transfected with either a negative control siRNA (Invitrogen) or targeting siRNA to deplete the target genes for 24 hours.

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PMC6487404

The volume of the buffer on the apical and basolateral side of the cell layer was 0.3 mL and 0.7 mL, respectively.

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PMC9727330

Flow cytometry fractionation quantifies the kinetic profile of ASNS protein expression in Caco-2 cells treated with 4 mg/ml of each amino acid compared to DMSO treated cells LDH Production in Treated Cancer Cells (Caco-2 Cells) NT, Untreated cells (Control) Levels of Produced Inflammatory Interleukins in Treated Cells.

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PMC9429973

Recent small series of clinical experience suggest the incidence to be about 10% at baseline and 30% at first relapse.

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PMC9000591

The most abundant group was isoflavones with six detected compounds, followed by triterpenes with three identified compounds.

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PMC11144382

The 5 MSS NFIX frameshift mutations in exons 6-8 comprised 3 deletions (c.819-732_1079-948del, c.819-471_1079-687del, c.819-592_1079-808del), an insertion (c.1037_1038insT), and a duplication (c.1090dupG).

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PMC11107915

Its ability to process and generate human-like text makes it a valuable tool in the healthcare ecosystem, particularly in fields where effective communication is crucial.

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PMC11345828

LCMS Method 1: RT = 2.159, 2.193 min, MS (ESI): mass calcd for C41H43Cl2N5O5, 755.3, m/z found, 755.8 (M + H).

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PMC8481254

We found that, compared to 5.5 mM glucose, 25 mM glucose had no effect on LATS1, LATS2, MST1, or MST2 (Fig. 2C).

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PMC11468365

The work in TranSynergy proposed a method that depends on the cellular effect of drug actions which can be modeled by gene dependencies and gene–gene interactions.

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PMC11400680

The proposed instance segmentation model is designed and validated using a large public dataset called EVICAN and achieved a favorable performance showing average mAP50 scores of 96.25, 95.05, and 94.18 for cell segmentation, and 68.04, 54.66, and 38.29 for nucleus segmentation on easy, medium, and different test sets of EVICAN, respectively.

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PMC9429973

MM is most frequently diagnosed among people >65 years of age and the median age at onset in Europe is 72 years.

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