Datasets:
OTAR3088
/
BioData-CellLine_annotated

Dataset card Data Studio Files
xet
Community
1
PMCID
string
Sentences
string
ner
list
PMC9429973
In the second one, the corresponding response rates were 57%, 49% and 100%, with no significant differences between treatment groups.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11675244
While the Wnt pathway is well-studied, its complexity presents challenges for direct targeting, prompting recent analyses of inhibitors acting at various stages of the signaling axis for potential selective anti-cancer effects.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11789597
Bubble plots showing the top five GO functional enrichment of genes significantly regulated by CAV1 in MM1S cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "Bubble", "plots", "showing", "the",...
PMC10196713
A valid and reliable therapeutic strategy for the treatment of platinum-resistant OC has not yet been established, and there is an urgent need to develop and establish an appropriate treatment.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10203589
FGF18 is a potent mitogen for a variety of cells and plays an important role in directing cancers in organs or systems such as digestion and reproduction (31).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11546117
In conclusion, primary hMECs were able to reproducibly form an epithelial barrier in vitro and the ability to distinguish between passive paracellular and transcellular transport routes, making them a promising in vitro model for the blood–milk barrier.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11321678
Then we explore the relationship between four subgroups and 24 scATAC clusters.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Then", "we", "explore", "the", "relationship", "between", "four", "subgroups", "...
PMC9341513
Simulations of the IGH-CCND1 reciprocal translocation in Z-138 cells revealed that an oncogenic fusion TAD is created, encompassing CCND1 and the IGH super-enhancers.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "token...
PMC6642070
As the target of RhoA, which is activated by prenylation, Akt phosphorylation is decreased with statin treatment .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "As", "the", "target", "of", ...
PMC9611901
The first layer of the gel consisted of 0.6% NMP agarose.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "first", "layer", "of", "the", "gel", "consisted", "of", "0.6", "%",...
PMC8409415
Strong CD70 expression was observed in A2780cisR and SKOV3cisR cells, moderate CD70 expression was observed in SKOV3 cells, and no CD70 expression was observed in A2780, OVTOKO, OVISE, and RMG‐I cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O"...
PMC11634027
We also attempted to address the significance of sequence conservation by assaying the ability of the human DCHS1 ICD to provide Ds-ICD function, using a hybrid transgene encoding the extracellular domain and transmembrane domain of Drosophila Ds and the ICD of DCHS1.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11538390
Participants in FinnGen provided informed consent for biobank research in accordance with the Finnish Biobank Act (law 688/2012).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Participants", "in", "FinnGe...
PMC11521786
The second group in both experiments did not receive any treatment during the immunization schedule.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "second", "group", "in", "both", "experiments", "did"...
PMC11781181
SLC7A11 is the target gene for miR-375-3p 20.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "SLC7A11", "is", "the", "target", "gene", "for", "miR-375", "-", "3p", "20", "." ] } ...
PMC10667689
Each cell line was cultured with 10 cells per mL per well seeding number for the Ctrl, PMA, and Gal-9 groups.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Each", ...
PMC5925824
One-way ANOVA was used for statistical analysis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "One-way", "ANOVA", "was", "used", "for", "statistical", "analysis", "." ] } ]
PMC7802142
Hu et al. prepared an oxidized sodium alginate hydrogel encapsulating dermal papilla cell-derived extracellular vesicles (DP-EVs) .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Hu", "et", "al.", "prepared", "an", ...
PMC11604768
Responding promoters of interest are highlighted.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Responding", "promoters", "of", "interest", "are", "highlighted", "." ] } ]
PMC8164677
Therefore, these findings can guide the further research and treatment options for ovarian cancer subtype of endometrioidal non serous origin.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", ...
PMC7987994
Significance codes according to p value: 0 ‘***’0.001 ‘**’0.01 ‘*’0.05 (two-sample t-test).Figure 3Relative metabolic activity of L929 cells (resazurin assay) after 24 h incubation with extracts of Zn_SPS.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11055510
It was found that upregulation of circMAN1A2 expression promoted OC cell growth.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "was", "found", "that", "upregulation", "of", "circMAN1A2", "expression", "...
PMC11055443
The IL-6 production in Caco-2 cells after 48 hours of incubation was 568.51 ± 63.26 pg/mL which was decreased to 23.92 ± 6.68 with V. cholerae exposure (P <0.0001).
[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8992508
The hydrophobic TMDs recognize and translocate a broad variety of substrates upon conformational changes, determining the characteristics of transported substrates.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "hydrophobic", ...
PMC11610461
Gene set variation analysis (GSVA) was performed using the R package “GSVA” to further explore the potential biological functions of PSENEN expression in KIRC (Zhang et al., 2022).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11257203
Giemsa stain and dimethyl sulfoxide (DMSO) were purchased from Merck (Germany).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Giemsa", "stain", "and", "dimethyl", "sulfoxide", "(", "DMS...
PMC11659921
Additionally, the PCA plot clearly illustrates the distribution of samples between these two clusters (Figure 3C).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "the", "PCA",...
PMC11286266
and max.
[ { "tags": [ "O", "O", "O" ], "tokens": [ "and", "max", "." ] } ]
PMC11594588
Other systems include enzymes such as superoxide dismutase, which catalyzes the dismutation of superoxide anions (O2) to O2 or H2O2, and catalase, which catalyzes the decomposition of H2O2 into H2O and O2.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11462673
F Western blot assay for LDB1 protein expression in acute leukemia cell lines and Healthy Donor T Cells Clinical characteristics of Pediatric T-ALL patients To elucidate the role of LDB1 in T-ALL, we conducted transfection experiments using LDB1-targeting short hairpin RNAs(sh-LDB1#1, sh-LDB2#1and sh-LDB1#3), along with control short hairpin RNAs (sh-NC) in Jurkat, 6 T-CEM and J.gamma1.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11790599
The OD determination at 515 nm was determined using a SpectraMax 190 microplate reader (Molecular Devices) following the addition of 200 μL of 10 mM Tris base solution (pH 10.5, Sigma Aldrich).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10975211
Buforins exhibit potent antimicrobial and anticancer properties, by disrupting bacterial cell membranes or interfering with intracellular processes.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Buforins", "exhibit", "potent", "antimicrobi...
PMC11697189
Among the cell lines we detected, the expression of HSPA7 was the highest in A498 cells and the lowest in OSRC2 cells (Fig. 9A).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "...
PMC11320834
Sequencing variant nomenclature was carried out in concordance with the Human Genome Variation Society (HGVS) guidelines to achieve a consistent approach to naming all variants.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Methods: We generated mice models carrying conditional/constitutive Ddx41 knock-out (KO) and conditional R525H knock-in (KI) alleles in various combinations.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC10547921
Very low concentrations of cryptophycin-52 (36) inhibited cell proliferation during mitosis (IC50 = 11 pmol/L) without significant changes in microtubule length or quality.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11788920
The transcribed RNAs were purified by loading them into different percentages of denaturing PAGE.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "transcribed", "RNAs", "were", "purified", "by", "loading", ...
PMC11773391
The inhibition rates of A375 and Sk‐MEL28 cells treated with various concentrations of TMZ were determined using the MTT assay to confirm the appropriate concentration of TMZ for subsequent experiments (Figure S1).
[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC9429973
Results: Primary EMD patients had less frequently advanced ISS (ISS 3) (OR 0.51 [95% CI: 0.42–0.63], p<0.001), high paraprotein levels (>20g/l) (OR 0.64 [95% CI: 0.54–0.76], p<0.001) and high PC infiltration of bone marrow (>10%) (OR 0.35 [95% CI: 0.30–0.42], p<0.001) when compared to reference MM patients.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3019555
Ago2 is necessary for MTD-induced inhibition of HIF-1α translation. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Ago2", "is", "necessary", "for", "MTD-induced", "inhibition", "of", "HIF-1α", "translation", "."...
PMC8524093
Despite the great social and economic burden caused by CHIKV infection, there is no vaccine or specific antiviral drugs currently available.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Despite", "t...
PMC9429973
In vitro treatment of human CLL cells (either cell lines or primary patient samples) with FL3 leads to a decrease in translation rate.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11342785
When TPPP-FL was targeted to DDX4 droplet-hubs, the MT-bundling triggered was strong, producing the highest density of MTs in bundles over a 10-h period.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9429973
Likewise, a positive correlation was found between neutrophil/ eosinophils ratio and blood urea, bilirubin, and C-reactive protein (p=0.047, r= 0.205; p=0.021, r= 0.249 and p= 0.0001, r= 0.377 respectively).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10243817
Subsequently, we studied the downstream mRNA expression in nasal epithelial cells after activation of TGF-β2/TGF-βR3 signaling.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Subsequently", ",", "we", "studied", "the", ...
PMC9429973
The median number of prior treatment lines was 3 (range 1-5).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "median", "number", "of", "prior", "treatment", "line...
PMC11700247
Interestingly, we observed a subset of A20 cells that escaped CART-19 attack, characterized by a loss of CD19 with sustained expression of B220 (Figure 7B-C).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10976516
Here we present an overview of OV therapy used against lung cancer and how to improve its efficacy using carrier cells for the systemic delivery of OVs.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9681981
Clostridium perfringens commonly resides in the gastrointestinal tract and can survive in different environmental conditions.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Clostridium", "perfringens", "commonly", "resides", "in", "the", ...
PMC11757131
This indicates that 3-HIB may be a key metabolite mediating the regulation of cellular lipid metabolism via valine.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "indicates", "that", "3-HIB", "...
PMC7802142
All settings of imaging and processing were kept constant.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "settings", "of", "imaging", "and", "processing", "were", "kept", "constant", "." ] } ]
PMC11290772
The SKOV-3 ovarian cell line was obtained from Procell Biotech Corporation (CL-0215, Wuhan, China) and overexpressed ROBO1 using the pEE6.4 plasmid (GM-1013PA02, Genomeditech, Shanghai, China).
[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7185206
This process was overseen and approved by the Mayo Clinic Institutional Review Board (IRB, protocol number 15–000934).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "process", "was", ...
PMC4443654
A more conservative definition of structurally variable regions is that they are regions altering their compartment state (between A and B compartments) in one cell type relative to the other two.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Aims: Our aims were to identify, quantify and compare TE expression in different stages of MDS on a larger cohort of patients to provide a deeper insight into their occurrence and possible roles in MDS.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11171319
In agreement with this observation, our data indicate that the oncogenic potency of HCMV clinical strains varies between low- and high-risk strains .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", ...
PMC10890307
The kinetic parameter qP Lactate is usually associated with qS Glucose because cells can produce more lactate when they consume more glucose.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "kinet...
PMC9429973
Simple tests like platelet glycoprotein flowcytometry or MYH9 staining can confirm the diagnosis in a substantial number of patients.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Simple", "tests", "like", "platel...
PMC7961460
This suggests a possible pattern of glycosylation or other post translational modifications on the full-size isoform.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "suggests", "a", "possible", "pattern", "of", ...
PMC11687663
The PyMol 2.5.2 command for RMSD calculation was used to obtain quantitative information on structural similarity.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "PyMol", "2.5.2", "command", "for", "RMSD", ...
PMC9429973
In addition, TET2-deficient lymphomas select for high expression of the pro-survival BCL2 family protein BCLXL, potentially providing protection from MYC-driven apoptosis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", ...
PMC10882807
This platform contributes to circRNA-protein studies .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "platform", "contributes", "to", "circRNA-protein", "studies", "." ] } ]
PMC9027909
Comparisons were carried out using the Student’s t-test The correlation between the expression of il-8 and il-15 genes with investigated miRNAs was assessed and showed that only il-8 had a significant correlation with mir-29a (P-value = 0.007) and mir-874 (P-value = 0.011), while the correlation between il-8 and il-15 and all other miRNAs was not statistically significant.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11087766
Cells infected with wild-type PhiKZ lysed at an average of 62 mpi (n = 12) as determined by the time at which 50% maximal fluorescence was reached, whereas lysis of cells infected with PhiKZ PicA T367P was delayed until an average of 75 mpi (n = 12) (Fig. 4A).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11424574
Among adults, osteosarcoma is the third most common tumor after chondrosarcoma and chordoma.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Among", "adults", ",", "osteosarcoma", "is", "the", "third", "mo...
PMC11257988
Immunoblotting results showed that KRASG12D mutation activates RhoA and further eliminates the activation of Wnt/β-catenin protein signaling, reducing the metastatic activity of KRASG12D-mutated NSCLC.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11723947
b–d and I, j Data are represented as mean ± SEM of three independent experiments.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "b", "–", "d", "and", "I", ",", ...
PMC9429973
Of these, approximately 90% of patients present with warm AIHA (wAIHA), which occurs when pathogenic IgG antibodies bind to RBCs at a temperature of ~37 °C.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Flow cytometry analysis of bone marrow (BM) cells from 17-20 weeks kank1 old mice showed minor increase in CD3 T-cell population, while the expression of the double positive B220/CD19 B-cells population was reduced in Kank1 compared to Kank1.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11538390
All subjects have been recruited by general practitioners and physicians in hospitals and during promotional events.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "subjects", "have", "been", "recruited", "by", ...
PMC7090062
Intriguingly, miR-30a knockdown in the context of siRNA-mediated beclin-1 inhibition displayed no significant difference in IM sensitivity compared to that of the cells transfected with beclin-1 siRNA alone (Fig. 7).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
M. Boada, N. Trias, A. Brugnini, C. Guillermo, S. Grille Catedra de Hematologia; Laboratorio de Citometria y Biologia Molecular.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11443022
A 32-year-old man could not ejaculate, with post-orgasmic urinalysis revealing minimal sperm presence.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "32-year-old", "man", "could", "not", "ejaculate", ",", "wit...
PMC9429973
Results: We included a total of 72 AML patients who were genotyped for KMT2A-PTD with both PCR and Hybridization capture NGS.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", ":...
PMC11617590
Dulbecco's modified Eagle medium (DMEM), antibiotic antimycotic solution, and 0.25% trypsin‐ethylenediaminetetraacetic acid (EDTA) used for cell culture were purchased from HyClone (Logan, UT, USA), and fetal bovine serum (FBS) was purchased from Atlas Biologicals (Fort Collins, CO, USA).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10589262
This difference was attributed to species-specific posttranslational modifications .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "difference", "was", "attributed", "to", "species-specific", "posttranslational", "modifications", "." ] } ]
PMC11604830
1 ppm upfield from water protons, which could be detected and monitored, using water suppression pulse sequences, in different acquisition settings such as PRESS, image‐selected in vivo spectroscopy (ISIS), and CSI acquisitions. , , , , , ,
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11377827
Cells were plated in FluxPak 96-well plates in DMEM plus 10% FBS at a cell density of 2 × 10 with or without 100 µM Roxadustat and incubated at 37 °C for 24 h. The medium was replaced with XF DMEM, pH 7.4 (Agilent Technologies) supplemented with 1 mM sodium pyruvate, 2 mM l-glutamine, 10 mM glucose and incubated at 37 °C in a non-CO2 incubator for 1 h before replacing with the same medium before measuring in the analyser.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11320834
One mL of the liposomal formulation was added to dialysis bags (15 kDa MWCO, Spectra/Por, Spectrum Laboratories, Inc., Piscataway, NJ, USA) and immersed in the release medium in 50 mL tubes to provide sink conditions.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11224020
Outliers were calculated using a ROUT test (Q = 1%) represented in gray (N = 4 independent experiments; left, n = 348 cells in 4 µm, n = 314 cells in 3 µm, n = 211 cells in 2 µm; middle, n = 201 cells in 4 µm, n = 206 cells in 3 µm, n = 176 cells in 2 µm; right, n = 215 cells in 4 µm, n = 187 cells in 3 µm, n = 180 cells in 2 µm).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6742971
Figure 4C displays the IFN-γ Elispot peptide titration curves, showing the functional avidity of the clones used for adoptive transfer to NSG-A2 mice.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11429241
Here, it is important to note that the scaffold height of 1 mm exceeded the free working distance of ∼0.55 mm of the applied 20× 0.8 NA objective lens.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11594641
The loss of RAB27B in the HCC cell line (hepatocellular carcinoma) inhibited the PI3K/AKT signaling pathway, leading to suppression of cell proliferation .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11585587
In addition, poly-ADP ribose polymerase (PARP) is a polymerase that plays a crucial role in the repair of cellular DNA damage.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973
Results: A laboratory findings reported in association with COVID-19 included leukopenia, lymphopenia, monocytosis, neutrophilia, eosinopenia, These abnormalities mainly highlight the severe, transitory and reversible perturbation of myelopoiesis, especially in the form of accelerated and disordered granulopoiesis, in patients with COVID19 in severe symptomatic phase.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11297139
Only the contacts between EWS/FLI1-bound upregulated cREs and their linked upregulated genes are shown.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Only", "the", "contacts", "between", "EWS/FLI1-bound", "upregulated", ...
PMC10878518
The scale bars represent 1 mm and 500 μm in the top and bottom panels, respectively. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "scale", "bars", "represent", "1...
PMC9429973
Results: As of the Sep 6, 2021 data cutoff, 18 patients have been treated in part 1 of the study with sabatolimab + AZA + VEN (Cohort 1, n=5; Cohort 2, n=13).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11545868
Isoflavone glucosides are isoflavones bound to glucose molecules and are a subgroup of isoflavones, a class of phytochemicals found in plants, especially legumes such as soybeans and soy products.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11380454
Overall, VLA-4 integrin signaling is critical for tumor immune evasion and is a potential target for cancer treatment.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Overall", ",", "VLA-4", "integrin...
PMC4355729
786-O and A-704 cell lines showed higher expression of PIK3R1 compared with that of HK2 cell line (Supplementary Fig. 1).
[ { "tags": [ "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": ...
PMC10443665
Over-expression of these transporters can lead to MTX resistance (89101112).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Over-expression", "of", "these", "transporters", "can", "lead", "to", "MTX", "re...
PMC10933092
However, little is known about the links between chemical modifications of messenger RNAs (mRNAs) and long noncoding RNAs (lncRNAs) and their function in bladder cancer (BLCA).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Further, interactions between ICM-expressions on healthy (fresh) donor T-cells could have an impact in therapy responses and should be evaluated in donor selection.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9429973
Median OS is 14.7 mo from surgery (range 6.1-28.4 mo; 10.8 mo post Temferon).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Median", "OS", "is", "14.7", ...
PMC11740573
Its absence in gram-positive bacteria allows substances to penetrate and/or damage cell membrane more easily .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Its", "absence", "in", "gram-positive", "bacteria", "allows", ...
PMC10798140
Interestingly, compound 3e did not show any cytotoxic effects on the treated fibroblasts at both high and low concentrations, while 3c, 3d, and sorafenib showed a significant decrease in the number of healthy cells and an increase in the number of necrotic cells when compared to the control, untreated cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11365427
In conclusion, our study has demonstrated the crucial role of phenylalanine levels in MM diagnosis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "conclusion", ",", "our", "study", "has", "...
PMC11696576
AVX002, AVX235, and AVX420 were stored at −80 °C in DMSO.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "AVX002", ",", "AVX235", ",", "and", "AVX420", "were", "stored", ...
PMC10729469
Additionally, there was no significant changes in Aβ tetramer reactive CD4+ CD25- cell populations in all treatments compared against APP/PS1 mice.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additio...