Datasets:
OTAR3088
/
BioData-CellLine_annotated

Dataset card Data Studio Files
xet
 Community
1
PMCID
string
Sentences
string
ner
list
PMC8913139
For instance, downregulated miR-448 was found to alleviate spinal cord ischemia/reperfusion injury by upregulating SIRT1 .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "instance", ",", "downregulated", "miR-448", "wa...
PMC11703992
The GENIE3 was used for identification of TF targets via constructing co-expression network, then the enrichment of TF-motif and discovery of direct TF target were completed by RcisTarget.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11773391
Multiple film exposures were obtained to verify the linearity of the samples analysed.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Multiple", "film", "exposures", "were", "obtained", "to", "verify", "the", ...
PMC11727907
4053, Cell Signaling Technology, Beverly, MA, USA) for 30 min at room temperature (RT).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "4053", ",", "Cell...
PMC5535901
In the acidic environment of the stomach, I3C forms complex mixture of bioactive compounds, such as the dimer 3, 3’-diindolylmethane (DIM) .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11499381
Internalization of the CLR/RAMP1 complex following stimulation with CGRP is well documented, hence we explored whether BiFC fusions influenced the ability of the receptor complex to internalize .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11745600
Scale bar, 200 μm. *
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bar", ",", "200", "μm", ".", "*" ] } ]
PMC11638255
Tumor microenvironment (TME) data (excluding TGF-β) are presented as mean ± SEM, n = 10 (Control) and n = 6 (TEPA) biological replicates, one independent experiment.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11461833
from the mean expression level).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "from", "the", "mean", "expression", "level", ")", "." ] } ]
PMC11420784
n = 3 slides.
[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "n", "=", "3", "slides", "." ] } ]
PMC9429973
Pathway analyses of CALR-mutant megakaryocyte progenitors (MkPs) were performed on Genotyping of Transcriptome (GoT) data from patients with Essential Thrombocytosis (ET).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11409031
As a validation set, GSE140082 contains mRNA expression and related clinical information from 380 OV tissues.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "As", "a", "validation", "set", ",", "GSE140...
PMC11672881
These findings suggest that the combination treatment acts as a pro-oxidative therapy, leveraging elevated oxidative stress to induce cell death in melanoma cells while disrupting their antioxidant defenses.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11257988
SOS1 is a key guanine nucleotide exchange factor (GEF) for KRAS, which binds to KRAS protein at its catalytic binding site and promotes the exchange of GDP for GTP, thereby activating the KRAS protein.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10988808
3CCDC25 suppress Hippo pathway by promoting YAP phosphorylation and inhibiting its nuclear entry.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "3CCDC25", "suppress", "Hippo", "pathway", "by", "promoting", "YAP", "phosph...
PMC11697189
Expression of HSPA7 in ccRCC cells detected by Western blot. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Expression", "of", "HSPA7", "in", "ccRCC", "cells", "detected", "by", "Western", "blo...
PMC11066331
The cell suspension in ABC was then mixed with SA matrix to reach the final concentration 12.5 × 10 cells per mL. 2 μL of the suspension containing 25 × 10 cells were spotted on 384-well steel target plate in technical replicates (n = 5) and dried at room temperature under dust-free conditions.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7612475
In keeping with our previous findings, SF3B1 depletion led to a significant decrease in cell survival in response to both etoposide and olaparib, suggesting that the role of this protein in HR is crucial to promote cellular survival following DNA damage (Fig. 1E and F).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11711127
As T cells progress to the effector stage through successful stimulation, exhaustion and senescence step in, mitigating excessive inflammation and preventing potential immunopathological consequences.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11434983
Upon coordination of PPh3, characteristic shifts are noted for protons of the pyridine moiety and the imine proton, as expected.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Upon", "coor...
PMC11756514
Finally, we examined the binding of a soluble form of langerin to S. aureus.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Finally", ",", "we", "examined", "the", "binding", "of", ...
PMC11544122
No detectable BRET was measured when Rluc8-SNX9 was transfected alone.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "No", "detectable", "BRET", "was", "measured", "when", "Rluc8-SNX9", "was", "transfected", "alone...
PMC11635519
The secretome library is composed of 92,918 peptides.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "secretome", "library", "is", "composed", "of", "92,918", "peptides", "." ] } ]
PMC11721587
The resultant medium was filtered and harvested.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "resultant", "medium", "was", "filtered", "and", "harvested", "." ] } ]
PMC11365427
Green arrows represent downregulated metabolites, and red arrows represent upregulated metabolites.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Green", "arrows", "represent", "downregulated", "metabolites", ",", "and", "red", ...
PMC11612626
Global proteomic integral stability assays determined that compound A binds to the proteasome structural subunit PSMA1 and promotes association of the proteasome activator PA28α/β (PSME1/PSME2) with immunoproteasomes.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11721064
A gradual decrease in CK12 + epithelial cells and an increase in vimentin + mesenchymal cells were observed with each passage (Fig. 2B) (p < 0.001).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10114490
Gold-standard cell model is primary cultured human hepatocytes, but they are scarce and expensive for routine testing.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Gold-standard", "cell", "model", "is", ...
PMC11760643
C, E) Responses were normalised to maximum ATP response in each experiment.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "C", ",", "E", ")", "Responses", "were", "normalised", "to", ...
PMC10204952
Because the interstitial concentration of S1P is about 10 times higher than its cellular level, we undertook a secretome analysis to understand how S1P would affect the secreted protein profile of differentiated SGBS adipocytes.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11756514
Langerin, on the other hand, is found as a trimer on a cell membrane; further clustering at the membrane would increase multivalency.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10882807
EIF4A3 is an RNA-binding protein of hsa_circ_0005397, which overexpressed in paired HCC tissues and cell lines.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "EIF4A3", "is", "an", "RNA-binding", "protein", ...
PMC11188874
A total of 1,771 peptides were detected at 1% PSM FDR (based on forward/decoy database searching).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "total", "of", "1,771", ...
PMC11656380
Moreover, alanine scanning analysis identified four critical hydrophobic amino acids in the RAM13 domain essential for its cytotoxicity.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "alanine", "scann...
PMC2614416
At the same time, the enzymes that channel these strategic intermediates toward de novo biosynthesis of purine nucleotides and DNA/RNA are found to increase with increasing severity of the disease.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11774747
CAR, Chimeric Antigen Receptor; CD, Cluster of differentiation; CMV, Cytomegalovirus; CMVST, Cytomegalovirus Virus Specific T cell; DC, Dendritic Cell; EBV, Epstein-barr virus; EBVST, Epstein-barr Virus Specific T cell; GD2, disialoganglioside; HER2, Human Epidermal Growth Factor Receptor 2; IFNγ, Interferon gamma; IL,...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7433824
Glioblastoma cell lines—U87 and A172—were seeded in complete medium in 96‐well E‐plate at a density of 5000 cells/well and 7500 cells/well, respectively.
[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ],...
PMC11127909
Experiments were performed three times (N = 3).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Experiments", "were", "performed", "three", "times", "(", "N", "=", "3", ")", "." ] ...
PMC11496728
Knockout and validation of Apaf1 gene in CHO cells. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O" ], "tokens": [ "Knockout", "and", "validation", "of", "Apaf1", "gene", "in", "CHO", "cells", ".", ...
PMC11317131
After electroporation the cells were transferred to a 6-well plate.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "electroporation", "the", "cells", "were", "transferred", "to", "a", "6-well", "plate", ...
PMC11267830
g The knockdown of RBM39 affects cell colony formation and proliferation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "g", "The", "knockdown", "of", "RBM39", "affects", "cell", "colony", "formation", "and...
PMC11694625
Weight changes are an essential indicator for evaluating a drug's toxicity.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Weight", "changes", "are", "an", "essential", "indicator", "for", "evaluating", ...
PMC11519583
Data in bar graphs are expressed as mean ± SD (*p < 0.05, **p < 0.01, ***p < 0.001, a: Holm’s test, b–d: Dunnett’s test).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11521786
Considering all these results, we then evaluated the antitumor effect of vaccination with the Mv-HER3 candidate in the murine 3LL-R3 tumor cell line.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O" ], "token...
PMC9611901
The results of the alkaline comet assay (Figure 1) show statistically significant increases in the levels of %DNA in the tail (A) and tail length (B) in the treated HepG2 cells after 24 h of exposure to the tested leather samples compared to the negative control (p < 0.05; Mann–Whitney U test).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9596868
G, H) Percentage cell viability after combination treatment with quercetin and MST-312 in OSE cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "G", ",", "H", ")", "Percentage", "...
PMC9429973
CRS was reported in 15 pts (50%; G1 30%, G2 13%, G3 7%).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CRS", "was",...
PMC11361748
S1 Table) diluted in the blocking buffer.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "S1", "Table", ")", "diluted", "in", "the", "blocking", "buffer", "." ] } ]
PMC9792775
p < 0.05, **p < 0.01, ***p < 0.001, ns not significant.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "p", "<", "0.05", ",", ...
PMC8164677
Shows 2D interactions of the best pose of (A) mammalian target of rapamycin (mTOR1) with wedelolactone; (B) mammalian target of rapamycin (mTOR1) with sirolimus; (C) nuclear factor erythroid 2–related factor 2 (Nrf2) with wedelolactone; (D) nuclear factor erythroid 2–related factor 2 (Nrf2) with trigonelline; (E) hypox...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8567602
The other clusters demonstrated some expected variations between synovial sarcoma and MRT/EpS (Supplementary Fig. S2A).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "other", "clusters", "demonstrated", "some"...
PMC11394730
Furthermore, PTL reduced the expressions of Cyclin D1, B-cell lymphoma-2 (Bcl-2), and B-cell lymphoma-extra-large (Bcl-XL), as well as triggered apoptosis in C918 cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11673902
They then used the method to measure the deformability of activated lymphocytes from patients with chronic lymphocytic leukemia and showed that the deformability of lymphocytes from patients with slow gonorrhea was lower than that of controls .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11772449
Knockdown of p38γ can reduce the level of autophagy in cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Knockdown", "of", "p38γ", "can", "reduce", "the", "level", "of", "autophagy", "in", ...
PMC11763126
Biotinylated CBDP1 and Scr peptides were synthesized by SciPeptide Technology (Shanghai, China).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Biotinylated", "CBDP1", "and", "Scr", "peptides", "were", "...
PMC9429973
CNS relapse & medullary relapse was noted in 7.1% (n=14) & 9.1% (n=18) patients respectively.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CNS", "relapse", ...
PMC11772585
It has been documented that an increase in ATF4 levels, triggered by the downregulation of the mitochondrial electron transport chain in Drosophila eye progenitor cells, led to heightened proliferation by inducing a Warburg-like phenotype .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4485648
Of note, simultaneous treatment with SFN and acetazolamide, a pan-carbonic anhydrase inhibitor that also inhibits CA IX, was very effective in the bronchial carcinoid cell lines both in vitro and in vivo (55).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10154881
To analyze tumor infiltrating lymphocytes, tumor tissue was excised, minced, and digested in 20 U/mL type I collagenase (Wako), 60 U/mL DNase I (Worthington Biochemical) in RPMI1640 medium (Sigma‐Aldrich) for 30 min, followed by filtration through a 70‐μm cell strainer.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3734024
Diagram of B cell co-culture experiments with CD40L-expressing fibroblasts for study of the effects of IL-5 on B cell growth and function. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Diagram...
PMC11727638
After 10 days of culture, the cells filled the hemispherical cavities of the Cell Domes (Figure 3a–c).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "10"...
PMC9429973
This allowed use to more clinically relevant concentrations to achieve a 60% of MLL/AF4 and downstream target genes.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "allowed", "use", "to", ...
PMC9577200
The below primer pairs for target genes and B-actin were selected from the primer bank website.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "below", "primer", "pairs", "for", "target", ...
PMC11755519
To present the research situation regarding the impact of EVs on the development and metastasis of bladder cancer, publications from 2013 to April 2021 were selected.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9031474
The cell cycle comprises a series of cellular events during the growth and division of cells .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cell", "cycle", "comprises", "a", "series", ...
PMC11377827
Transcript levels of genes were normalised to a reference index of a housekeeping gene (β-actin).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Transcript", "levels", "of", "genes", "were", ...
PMC10253973
Liu et al. described Ru(II) polypyridine complexes, which caused the formation of singlet oxygen in methanol, mitochondrial accumulation and two-photon absorption (TPA).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
In L1, over the 2017-2020 study period, patients received treatment with PI (58.6%), IMID (32.1%), PI/IMID (4.2%), anti-CD38 (1.3%) or other molecules (3.8%).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11615828
Besides EMTB, we also tested the possibility of using other MAPs.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Besides", "EMTB", ",", "we", "also", "tested", "the", "possibility", "of", ...
PMC5308810
A selective removal of CXCR4 from doxorubicin-resistant A2780/ADR could recover the sensitivity to drug treatments.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "selective", "removal", "of", "CXCR4", "from", ...
PMC11365427
Furthermore, micro-CT scans and hematoxylin and eosin (HE) staining of the distal femur and lumbar vertebrae revealed that the phenylalanine-deprivation group exhibited fewer losses in the trabecular structures of the femurs and lessened vertebral erosion (Fig. 4L and Fig. S5C).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9325715
The determined ΔG for the first adsorption stage gradually decreased depending on the concentration of the utilized Fe and was in the range from − 24.82 to − 15.40 kJ/mol (the shown values represent Gibbs free energy observed for the lowest and highest Fe concentrations).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3164356
Using this metric, a correlation matrix was generated between all the N50 scaffolds.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Using", "this", "metric", ",", "a", "correlation", "matrix", "wa...
PMC11612626
Results indicated that compound A was well-tolerated in vivo and did not induce appreciable changes in TBW, appetite, gait, skin turgor, or neurologic or musculoskeletal systems (Supplementary Fig. S8C).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11673902
This method achieves both high test speeds and greater deformation of the cells under test.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "method", "achieves", "both", "high", "test", "speed...
PMC11775197
Targeted miRNA-based therapies offer insights into potential treatments for glioma .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Targeted", "miRNA-based", "therapies", "offer", "insights", "into", "potential", "treatments", "for", ...
PMC11742290
A humanized monoclonal LGR5 antibody - BNC101 targeting LGR5 in tumor biopsies was evaluated in safety and dose escalation phase I clinical trials in patients with recurrent metastatic CRC .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11730320
Four variants were heterozygous in dominant genes and did not appear in gnomAD or in the parents; however, none occurred in a gene (GJC2, HNRNPDL, HLA-DRB1) with immune function or phenotype consistent with the proband’s (Supplementary Dataset 1).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10530622
Several metabolic diseases such as obesity or diabetes have a degree of dysbiotic microbiota associated and are also risk factors for lithiasis .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Several", "m...
PMC10604092
Additionally, the definition of cachexia in our model concurred with the cancer cachexia-specific definition advocated by Fearon et al. in 2006, which states that cancer cachexia is associated with weight loss, decreased food intake, and systemic inflammation .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11781181
Cells that had reached 40-60% confluence were stimulated with plasma-derived exosomes (100 μg/mL).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", "that", "had", "reached", "40"...
PMC7553912
In addition, Western blot analysis confirmed the significant suppression of protein expressions of these crystal-binding molecules in OSMRβ mice on day 3 (Fig. 4a,b) and day 6 (Fig. 4c,d).Figure 3Gene expressions in the kidney of WT and OSMRβ mice after GOx injection.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8913139
The reversal effect of ROCK1 on Bcl-2/Bax expression was also found in A-172MG cells (Figure 5(c)).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "reversal", "effect", ...
PMC10965680
The average number of ROHs in Xiangdong goats is relatively high, which may provide a reference for the breeding and conservation of these goats since animals with high levels of ROH could be excluded or assigned lower priority for mating to minimize the loss of genetic diversity (Chen et al., 2020).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9532503
Our approach to increase afucosylation by simple modulation of osmolality yielded higher ADCC activity and FcγRIIIa binding affinity in the test antibody compared to the commercially available anti-CD20 antibody.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11419566
Furthermore, PA was found to be effective in the treatment of gastric cancer (GC), pancreatic cancer, and others.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Further...
PMC11180402
Consequently, identifying more effective and less toxic chemotherapeutic alternatives is critical for enhancing clinical outcomes for BC patients.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Consequently", ",", "identifying", ...
PMC11750165
M, 100-bp DNA size marker.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "M", ",", "100-bp", "DNA", "size", "marker", "." ] } ]
PMC11627398
Therefore, there is an urgent need for the development of new biomarkers for the early diagnosis of septic shock.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "there", ...
PMC11543885
Markov clustering algorithm (MCL) is used to group the interaction subnetworks with the inflation value of 3.0.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Markov", "clustering", "algorithm", ...
PMC11731614
Keratinocytes detect touch stimuli in the skin and transmit mechanical information related to pressure and brushing (Mikesell, 2022, Moehring, 2018).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10728200
The resulting images were captured using Zeiss LSM780 Laser Scanning Confocal Microscopy (Carl Zeiss, Jena, Germany).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "resulting", "images",...
PMC9429973
Seventeen of them had non-Hodgkin lymphomas, 9 multiple myeloma, 6 chronic lymphocytic leukemia, 6 acute myeloid leukemia, 3 Hodgkin lymphoma, 2 acute lymphoblastic leukemia, 2 myeloproliferative neoplasm, 1 Waldenstrom macroglobulinemia and 5 had other HM diagnosis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11190062
RPMI-8226 cells depleted for TLR4 (TLR4 KO), TLR9 (TLR9 KO), and control/mock (WT) cells were generated by gene editing using CRISPR/Cas9 as previously described (23).
[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11401358
5 Study of the structural changes in SF antioxidants. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "5", "Study", "of", "the", "structural", "changes", "in", "SF", "antioxidants", ".", "(" ...
PMC6181431
Previously we have reported that response to rapalog therapy in RCC is associated with mutation in the mTOR pathway genes: TSC1, TSC2, and MTOR .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11738017
Equally, with teclistamab at the recommended phase 2 of 1500 μg/kg, a high sBCMA level was also associated with significantly lower overall response rates, although there was no effect on its pharmacokinetics.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11388384
Trace reflects mean +/− SEM. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Trace", "reflects", "mean", "+", "/−", "SEM", ".", "(" ] } ]
PMC11476004
SCE frequency increases in animals in the case of disease .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "SCE", "frequency", "increases", "in", "animals", "in", "the", "case", "of", "disease", "."...
PMC11718809
The synthesized cDNA underwent purification and end-repair, followed by 3′-end adenylation and adaptor ligation with the NEBNext Ultra RNA Library Prep Kit for Illumina (New England Biolabs Inc., Ipswich, MA, USA).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...