OTAR3088/BioData-CellLine_annotated · Datasets at Hugging Face

PMCID string	Sentences string	ner list
PMC11291490	Following stimulation, lymphocyte proliferation was assessed by measuring the optical density at 450 nm (OD450) using a CCK-8 kit (Solarbio, China), following the manufacturer’s instructions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11679326	Lectins and lectin-like molecules of marine organisms have long been considered exclusively as molecules that provide innate immunity via opsonization facilitating phagocytosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Lectins", "a...
PMC9429973	Image: Summary/Conclusion: Overall, COVID-19 related mortality in patients with haematological malignancy has significantly declined over the course of the pandemic.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Image",...
PMC7841189	Experiments were performed in triplicate. *	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Experiments", "were", "performed", "in", "triplicate", ".", "*" ] } ]
PMC10936243	Provide a safe and secure place.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Provide", "a", "safe", "and", "secure", "place", "." ] } ]
PMC9429973	All methods were carried out in accordance with relevant guidelines and regulations.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "methods", "were", "carried", "out", "in", "accordance", "with", "relevant...
PMC11462673	Moreover, LDB1 plays an irreplaceable role in early development of the posterior forebrain and thalamus .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "LDB1", "plays", "an", "irreplaceable"...
PMC11638255	Concerning neuroblastoma, we have previously reported elevated levels of the high-affinity copper transporter 1 (CTR1) in neuroblastoma clinical samples and preclinical models, and recently demonstrated that intratumoral copper levels regulate the expression of the immune checkpoint molecule Programmed Death-Ligand 1 (...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Additional chromosomal aberrations were detected in all but one patient with the deletion of CDKN2A gene being the most frequent one.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additional", "chromosom...
PMC11321678	Annotation with cis‐regulatory elements and gene scores revealed that our samples covered all four MB molecular subgroups.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Annotation", "with", "cis‐regulatory", "elements", ...
PMC6024716	The CRISPR driven disruption of OAZ1 in the selected cell lines was confirmed by alignment of the CRIPSR treated sequences with the parental sequence.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC8777939	Sphere size was calculated using the following formula: sphere volume = 4/3πr.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Sphere", "size", "was", "calculated", "using", "the", "following", "formula...
PMC11011837	Conversely, the SFA/PUFA ratios are all higher than 1, signifying a greater presence of saturated fatty acids than polyunsaturated fatty acids inside the cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9429973	GCB types were constituted 18 cases (48.6%).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "GCB", "types", "were", "constituted", "18", "cases", "(", "48.6", "%", ")", "." ] } ...
PMC11746942	These findings collectively demonstrate that S1PR3 is a key orchestrator of psoriasiform dermatitis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "findings", "collectively", "demonstrate", "that", "S1PR3", "is", "...
PMC11545737	Thus, plasma membrane pores of 10–14 nm inner diameters are formed through which pro-inflammatory cytokines, such as IL-1β and IL-18 are released .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973	Data extraction was undertaken by one reviewer and validated by a second independent reviewer.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "extraction", "was", "undertaken", "by", "one", "reviewer", ...
PMC9813422	The goal of viruses is to replicate themselves, and some viruses pass their genomes on to the next generation along with the division of host cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11721277	DIPEA (39 µL, 0.2239 mmol) and HBTU (42 mg, 0.111 mmol) were added to the solution.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "DIPEA", "(",...
PMC9429973	Of 29 pts with paired flow cytometry for CD19 and CD22 prior to receipt of either INO/Blina, 4 pts (14%) lost CD19 expression and 3 pts (10%) lost CD22 expression at time of INO/Blina failure.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11513011	After 35 days for T24 cells and 83 days for 5637 and KK-47 cells after transplantation of the tumor, these mice were divided into a treatment group randomly with DIB (0.3 µg/mice) and control (DMSO) groups after tumors had grown to the ideal size.	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"...
PMC11699042	h Relative gene expression of A-673, HeLa, and MCF-7 cell lines after long-term culture for twelve months (m12 vs m0).	[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"...
PMC9429973	Three pts (7.3%) experienced CNS toxicity related to RG6234 (G1 and G3 headache; G1 confusion).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Three", "pts", "(...
PMC10772747	In addition, in vitro experiments were conducted using MTT method to evaluate the effects of EBE on the cytotoxicity of T47D cells, and the flow cytometry method was employed to determine the impact of EBE on apoptosis and the cell cycle.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", ...
PMC11792888	Additionally, combined etoposide/venom exposure provoked G2/M arrest and apoptosis in NSCLC more strongly than either substance alone.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "combined", "etoposide/v...
PMC11589157	The raw data have been deposited in the National Center for Biotechnology Information (NCBI) database, under project PRJNA1108630 (SRP525211), as well as the Genome Sequence Archive (accession number: CRA016205) of the National Genomics Data Center, under project PRJCA025566 (PacBio: SAMC3564548/CRX1037479; HiC: SAMC35...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11437637	1PBLs comparison in different groups of patients with EC.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "1PBLs", "comparison", "in", "different", "groups", "of", "patients", "with", "EC", "." ] } ]
PMC11590005	An epidemiological cross-sectional online survey was conducted using Google Forms.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "An", "epidemiological", "cross-sectional", "online", "survey", "was", "conducted", "using", "Google", ...
PMC11618052	LC-MS (m/z) for: C23H17N5OS (exact mass = 411.12); calculated [M + H]: 412.12; found [M + H]: 412.00.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10823017	Renal Cell Carcinoma (RCC) is the prevalent type of kidney cancer (85%); Clear cell RCC (ccRCC) is the predominant subtype (75%) of all the cases (1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11665555	In resistant BCa, knocking out OXCT1 restored gemcitabine sensitivity, and administering the nonmetabolizable βHB enantiomer (S-βHB) only partially restored gemcitabine sensitivity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11519583	Although MPs cannot differentiate into myofibers, in response to environmental cues, they secrete certain soluble factors to promote SC proliferation and differentiation, resulting in proper regeneration .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11279598	Whether the range of biological activities of honey is mediated by the same or different active compounds has not been fully studied.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Whether", "t...
PMC8389560	Blockade of intercellular communication via gap junctions attenuated the extent of apoptosis, for example, in BC31 cells , granulosa cells , or astrocytes .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O" ],...
PMC10674574	The pharmaceutical requirements define only the acceptance criteria for the validation of the Caco-2 cell line and do not specify the protocol for its implementation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ],...
PMC5839394	Figure 7A depict the interaction networks of the AgNPs-EPS regulated protein, in which is possible to observe a group of proteins biologically connected, with several interactions among themselves.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11683240	The wash steps were performed using FCS-free medium.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "wash", "steps", "were", "performed", "using", "FCS-free", "medium", "." ] } ]
PMC11615218	Importantly, the mere expression of CARs can increase proliferation and metabolic activity , and different single-chain variable fragments can lead to various rates of glucose and amino acid consumption in CAR-T cells .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10936243	The interviews revealed a wide range of different perspectives among participants; for example, some expressed the view that bedding should only be used for chronically ill patients or those having undergone major surgery.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6684588	These data indicate that locally administered ACE-083 causes focal growth of skeletal muscle in wild-type mice without evidence of systemic effects.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "data", "...
PMC7039683	This implies either these elements do not function as enhancers in zebrafish embryos, or they do not interact efficiently with the basal promoter in the vector.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11200978	CellEvent Green (ThermoFisher, Waltham, MA, USA, C10423) and SytoxRed (ThermoFisher, S11380) were used to assess apoptosis and necrosis, respectively, in samples following experimentation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11633763	The Co‐IP assay indicated that USP22 and HK2 did not interact directly (Figure 6A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "Co‐IP", "assay", "indicated", "that", "USP22", ...
PMC10788478	Sequence data are available through GEO under the accession number GSE218163 for LGR6 knockdown in HCC15 and A427 cells and GSE218164 for floating versus adherent A427 cell components.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "...
PMC11696576	b Top ten (i) oncogenic, and (ii) transcription factor target (C3) gene sets in MSigDB that overlapped with the genes upregulated after 16 h treatment with 0.5 μM AVX420.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8740518	However, a causal relationship has not been established.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "a", "causal", "relationship", "has", "not", "been", "established", "." ] } ]
PMC11718109	Scale bars, 10 μm.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bars", ",", "10", "μm", "." ] } ]
PMC9848491	We first to get related to the prognosis of patients with UCEC ER stress-related lncRNA used univariate Cox regression analysis, then we multivariate Cox regression analysis to obtain the ER stress related lncRNA, lncRNA prediction features related to establish ER stress.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11599565	In summary, we have established that several proteins, which are biologically characteristic of neuronal development, were overexpressed in ovarian carcinoma cells treated with platinum-derived drugs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "O"...
PMC11412721	The Mt2 gene, encoding the potentially oncogenic metallothionein-2 (Si and Lang, 2018), was less expressed in Trp53 Eμ-Myc male pre-tumoral splenic cells, which raised the possibility of its direct or indirect repression by p53, potentially through the binding of p53 or the DREAM complex at its promoter (Engeland, 2018...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11615218	Summary of the Food and Drug Administration-approved CAR-T cell products.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Summary", "of", "the", "Food", "and", "Drug", "Administration-approved", "CAR-T", "cell", "produ...
PMC11453018	The data represent mean ± SEM; p< 0.05, by one-way ANOVA (n=6).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "data", "represent", "mean", "±", "SE...
PMC6600592	Series of oxime-contained compounds with C6-C3 and C6-C4 skeleton were designed, synthesized, and assayed for anti-HBV activities.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Series", "of", "oxime-contained", ...
PMC10976516	In addition, studies with reovirus investigated how far these CCs might influence the balance of the ensuing antiviral vs. antitumor immune response.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", ...
PMC10178190	In addition, our results corroborate previous findings, showing synergistic activity of Crizotinib and platinum compounds in animal models of OC .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "additi...
PMC11297139	The representative images supported by the relevant statistics have been chosen upon three independent preparations with similar outcomes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "representative", "images", "supported...
PMC11201989	Next, we assessed the effect of double knockdown of PD-L1 and BBS5 on PC-2 ciliary localization.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O" ], "tokens": [ "Next", ",", "we", "assessed", "the", ...
PMC9388315	HSPs proteins participate in many processes such as angiogenesis, metastasis, and cancer cell metabolism .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "HSPs", "proteins", "participate", "in", "many", "proce...
PMC8345486	Interestingly, unmodified nucleosides or the adenosine modified with the nido-7,8-dicarbaundecaborate ion were ineffective on cancer cell biology.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Interestingly", ",", "unmodified", "nucleosi...
PMC5916734	Similar data were obtained for FIX secreted by BHK cells .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "Similar", "data", "were", "obtained", "for", "FIX", "secreted", "by", "BHK", "cells", ...
PMC11694066	They were further scaled to lie between 0 and 1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "They", "were", "further", "scaled", "to", "lie", "between", "0", "and", "1", "." ] }...
PMC11541409	C. Leaky activation.	[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "C.", "Leaky", "activation", "." ] } ]
PMC9429973	They included fungi of the genus Candida – 6.5% (C. albicans – 5.4% (n=5), C. crusei – 1.1% (n=1)) and Rhodotorula spp. –	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11697703	Titers of VSV-G pseudotyped viral particles were ∼10 IFUS/mL. Embryonic cortical cultures were prepared as previously described.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Titers", "of", "VSV-G", "pseudotyped", "viral", ...
PMC11283030	Qiang Liu: Writing – review & editing, Methodology, Investigation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Qiang", "Liu", ":", "Writing", "–", "review", "&", "editing", ",", "Method...
PMC9429973	BCX9930 is an oral Factor D inhibitor that targets the rate-limiting enzyme of AP with the potential to prevent both intravascular hemolysis and extravascular hemolysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11723947	It was proposed that the SUMO E3 ligase PIAS1 negatively regulates Treg development by maintaining a repressive chromatin state at the Foxp3 promoter through the recruitment of HP1γ.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11367939	Sigma Plot version 10.0 (Systat Software Inc., San Jose, CA, USA), Origin 2022b (OriginLab Corporation, Northampton, MA, USA) and SPSS (IBM Corp., Armonk, NY, USA) were used for statistical analyses.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Results: Established anti-leukemic drugs exhibited only weak synergism with venetoclax in high-risk AML samples.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", ":", "Established", "anti-leukemic", "drugs", "exhibite...
PMC9684669	Statistical analysis was performed using a one-way ANOVA with Tukey’s HSD correction (*** p < 0.001). (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Statistical", ...
PMC11321678	To investigate the chromatin accessibility heterogeneity in MBs, we performed scATAC‐seq (10X Genomics Chromium) on cells of frozen tumor tissues from 11 MB patients (Figure 1A; and Table S1, Supporting Information).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10899471	Moreover, this study also found that circulating miR-939-3p levels were higher in tumor patients than that in healthy individuals.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", "...
PMC10849234	1000 ng of purified messenger RNA (mRNA) was reverse transcribed to complementary DNA (cDNA) using the 5x All-In-One RT Master Mix kit (abm).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Better understanding of the gut microbiome could provide actionable information in guiding precision medicine.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Better", "understanding", "of", "the", "gut", "microbiome", "could", ...
PMC7369657	Statistically significant values were defined as p < 0.05 based on a two-tailed Student's t-test.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Statistically", "significant", "values", "were", "defined", ...
PMC9429973	Responses deepened over time with an ORR of 86% among the pts with at least 10 months follow-up.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Responses", "deepened", "over", "...
PMC9429973	Cumulative incidence functions were used for CRS and ICANS resolution rates.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cumulative", "incidence", "functions", "were", "used", "for", "CRS", "and", "ICANS", ...
PMC11674441	In this study, we retrospectively analysed the ability of our established neoantigen-pulsed DC (Neo-P DC) vaccine to induce an immune response in breast cancer patients.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3995603	RAW 264.7 cells were seeded at a density of 5×10 cells in a 48-well plate for the NO assay.	[ { "tags": [ "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "RAW", ...
PMC11247842	While GWAS identifies significant genetic markers, it is only the first step in the journey towards a comprehensive understanding of the underlying genetic mechanisms.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973	We propose a mechanism in which C/EBPα p30 mediates recruitment of TET2 to regulatory regions in the GATA2 gene to maintain its expression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", ...
PMC8010066	The overnight broth culture of Staphylococcus aureus ATCC25923 was adjusted to OD600:0.8.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "overnight", "broth", "culture", "of", "Staphylococcus", "aureus", "ATCC25923", ...
PMC11597291	Also, the GNR-4arm PEG system was evaluated on the inhibition and sonodynamic effect against ovarian cancer spheroids, resulting in reduced adhesion of the spheroids and reduced metastatic potential.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10587429	However, compared to clinical trials in human patients, our humanized model is only a fraction of the cost of a clinical trial.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11755519	Keyword combinations were selected for the search: ‘urinary bladder’ + ‘cancer’ + ‘development’/‘metastasis’ + ‘exosomes’/‘extracellular vesicles’.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10956161	Lung cancer is a malignant tumour that poses a serious threat to human health and its morbidity and mortality rates are among the highest in all cancers.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11413393	To better understand the observed cellular response to both MS023 treatment and the genetic knockdown of PRMT1, our next step was to profile transcriptomic changes via RNA-seq analysis in cell lines RCC243 and 786-0.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Radiological evidence for sclerotic lesions were found in 13 (81%) patients.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Radiological", "evidence", "for", "sclerotic", "lesions", "were", "fou...
PMC11732635	EBV is a widely prevalent herpes virus, with a global infection rate of around 95% (2).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "EBV", "is", "a", "wide...
PMC9812014	Some of these compounds have IC50 concentrations lower than 5 µM and may prevent viral infections by more than 90 percent.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Some", "of", "the...
PMC11697189	Clinical evaluation of the prognosis risk signature. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Clinical", "evaluation", "of", "the", "prognosis", "risk", "signature", ".", "(" ] } ]
PMC9351137	From left to the right: DAPI (blue), anti-α-tubulin (green), cytokinesis regulators (red), and merge.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9596868	DMSO treated cells served as vehicle control in all experiments. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "DMSO", "treated", "cells", "served", "as", "vehicle", "control", "in", "all", "experi...
PMC7812570	Fig. 5Inhibitory activity of GPI-anchored antibodies in transduced human CD4+ T cells during HIV-1 infection.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fig.", "5Inhibitory", "activity", "of", "GPI-anchored", ...
PMC11047729	Apart from ATRA, other substances also influence retinoic acid receptors: the novel retinoids, such as 9cUAB30, induce apoptosis and inhibit telomerase by down-regulating the hTERT gene in HL60 cells .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9370419	Next, we validated this conclusion by a Western blot assay (Figure 1K).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Next", ",", "we", "validated", "this", "conclusion", ...
PMC10204952	The respective seeding umber was 1 x 10 cells/well for MCF-12A, 1.5 x 10 cells/well for MDA-MB-231 and 2 x 10 cells/well for HCC1937.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "B-CellLine"...
PMC11634794	Expression of LAMP1 in different tumor types in TIMER2.0 database (P<0.05, P<0.01, **P<0.001).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Express...
PMC10198699	As such, the present scenario would likely not be actionable by a present-day Henrietta Lacks.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "As", "such", ",", "the", "present", "scenario", ...
PMC11095939	Data are presented as means ± SEM; n = 3. ****	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "are", "presented", "as", "means", "±", "SEM", ...

PMC11291490

Following stimulation, lymphocyte proliferation was assessed by measuring the optical density at 450 nm (OD450) using a CCK-8 kit (Solarbio, China), following the manufacturer’s instructions.

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PMC11679326

Lectins and lectin-like molecules of marine organisms have long been considered exclusively as molecules that provide innate immunity via opsonization facilitating phagocytosis.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Lectins", "a...

PMC9429973

Image: Summary/Conclusion: Overall, COVID-19 related mortality in patients with haematological malignancy has significantly declined over the course of the pandemic.

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PMC7841189

Experiments were performed in triplicate. *

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PMC10936243

Provide a safe and secure place.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Provide", "a", "safe", "and", "secure", "place", "." ] } ]

PMC9429973

All methods were carried out in accordance with relevant guidelines and regulations.

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PMC11462673

Moreover, LDB1 plays an irreplaceable role in early development of the posterior forebrain and thalamus .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "LDB1", "plays", "an", "irreplaceable"...

PMC11638255

Concerning neuroblastoma, we have previously reported elevated levels of the high-affinity copper transporter 1 (CTR1) in neuroblastoma clinical samples and preclinical models, and recently demonstrated that intratumoral copper levels regulate the expression of the immune checkpoint molecule Programmed Death-Ligand 1 (...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Additional chromosomal aberrations were detected in all but one patient with the deletion of CDKN2A gene being the most frequent one.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additional", "chromosom...

PMC11321678

Annotation with cis‐regulatory elements and gene scores revealed that our samples covered all four MB molecular subgroups.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Annotation", "with", "cis‐regulatory", "elements", ...

PMC6024716

The CRISPR driven disruption of OAZ1 in the selected cell lines was confirmed by alignment of the CRIPSR treated sequences with the parental sequence.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC8777939

Sphere size was calculated using the following formula: sphere volume = 4/3πr.

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PMC11011837

Conversely, the SFA/PUFA ratios are all higher than 1, signifying a greater presence of saturated fatty acids than polyunsaturated fatty acids inside the cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...

PMC9429973

GCB types were constituted 18 cases (48.6%).

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PMC11746942

These findings collectively demonstrate that S1PR3 is a key orchestrator of psoriasiform dermatitis.

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PMC11545737

Thus, plasma membrane pores of 10–14 nm inner diameters are formed through which pro-inflammatory cytokines, such as IL-1β and IL-18 are released .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC9429973

Data extraction was undertaken by one reviewer and validated by a second independent reviewer.

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PMC9813422

The goal of viruses is to replicate themselves, and some viruses pass their genomes on to the next generation along with the division of host cells.

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PMC11721277

DIPEA (39 µL, 0.2239 mmol) and HBTU (42 mg, 0.111 mmol) were added to the solution.

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PMC9429973

Of 29 pts with paired flow cytometry for CD19 and CD22 prior to receipt of either INO/Blina, 4 pts (14%) lost CD19 expression and 3 pts (10%) lost CD22 expression at time of INO/Blina failure.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11513011

After 35 days for T24 cells and 83 days for 5637 and KK-47 cells after transplantation of the tumor, these mice were divided into a treatment group randomly with DIB (0.3 µg/mice) and control (DMSO) groups after tumors had grown to the ideal size.

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PMC11699042

h Relative gene expression of A-673, HeLa, and MCF-7 cell lines after long-term culture for twelve months (m12 vs m0).

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PMC9429973

Three pts (7.3%) experienced CNS toxicity related to RG6234 (G1 and G3 headache; G1 confusion).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Three", "pts", "(...

PMC10772747

In addition, in vitro experiments were conducted using MTT method to evaluate the effects of EBE on the cytotoxicity of T47D cells, and the flow cytometry method was employed to determine the impact of EBE on apoptosis and the cell cycle.

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PMC11792888

Additionally, combined etoposide/venom exposure provoked G2/M arrest and apoptosis in NSCLC more strongly than either substance alone.

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PMC11589157

The raw data have been deposited in the National Center for Biotechnology Information (NCBI) database, under project PRJNA1108630 (SRP525211), as well as the Genome Sequence Archive (accession number: CRA016205) of the National Genomics Data Center, under project PRJCA025566 (PacBio: SAMC3564548/CRX1037479; HiC: SAMC35...

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PMC11437637

1PBLs comparison in different groups of patients with EC.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "1PBLs", "comparison", "in", "different", "groups", "of", "patients", "with", "EC", "." ] } ]

PMC11590005

An epidemiological cross-sectional online survey was conducted using Google Forms.

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PMC11618052

LC-MS (m/z) for: C23H17N5OS (exact mass = 411.12); calculated [M + H]: 412.12; found [M + H]: 412.00.

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PMC10823017

Renal Cell Carcinoma (RCC) is the prevalent type of kidney cancer (85%); Clear cell RCC (ccRCC) is the predominant subtype (75%) of all the cases (1).

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PMC11665555

In resistant BCa, knocking out OXCT1 restored gemcitabine sensitivity, and administering the nonmetabolizable βHB enantiomer (S-βHB) only partially restored gemcitabine sensitivity.

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PMC11519583

Although MPs cannot differentiate into myofibers, in response to environmental cues, they secrete certain soluble factors to promote SC proliferation and differentiation, resulting in proper regeneration .

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PMC11279598

Whether the range of biological activities of honey is mediated by the same or different active compounds has not been fully studied.

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PMC8389560

Blockade of intercellular communication via gap junctions attenuated the extent of apoptosis, for example, in BC31 cells , granulosa cells , or astrocytes .

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PMC10674574

The pharmaceutical requirements define only the acceptance criteria for the validation of the Caco-2 cell line and do not specify the protocol for its implementation.

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PMC5839394

Figure 7A depict the interaction networks of the AgNPs-EPS regulated protein, in which is possible to observe a group of proteins biologically connected, with several interactions among themselves.

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PMC11683240

The wash steps were performed using FCS-free medium.

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PMC11615218

Importantly, the mere expression of CARs can increase proliferation and metabolic activity , and different single-chain variable fragments can lead to various rates of glucose and amino acid consumption in CAR-T cells .

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PMC10936243

The interviews revealed a wide range of different perspectives among participants; for example, some expressed the view that bedding should only be used for chronically ill patients or those having undergone major surgery.

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PMC6684588

These data indicate that locally administered ACE-083 causes focal growth of skeletal muscle in wild-type mice without evidence of systemic effects.

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PMC7039683

This implies either these elements do not function as enhancers in zebrafish embryos, or they do not interact efficiently with the basal promoter in the vector.

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PMC11200978

CellEvent Green (ThermoFisher, Waltham, MA, USA, C10423) and SytoxRed (ThermoFisher, S11380) were used to assess apoptosis and necrosis, respectively, in samples following experimentation.

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PMC11633763

The Co‐IP assay indicated that USP22 and HK2 did not interact directly (Figure 6A).

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PMC10788478

Sequence data are available through GEO under the accession number GSE218163 for LGR6 knockdown in HCC15 and A427 cells and GSE218164 for floating versus adherent A427 cell components.

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PMC11696576

b Top ten (i) oncogenic, and (ii) transcription factor target (C3) gene sets in MSigDB that overlapped with the genes upregulated after 16 h treatment with 0.5 μM AVX420.

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PMC8740518

However, a causal relationship has not been established.

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PMC11718109

Scale bars, 10 μm.

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PMC9848491

We first to get related to the prognosis of patients with UCEC ER stress-related lncRNA used univariate Cox regression analysis, then we multivariate Cox regression analysis to obtain the ER stress related lncRNA, lncRNA prediction features related to establish ER stress.

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PMC11599565

In summary, we have established that several proteins, which are biologically characteristic of neuronal development, were overexpressed in ovarian carcinoma cells treated with platinum-derived drugs.

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PMC11412721

The Mt2 gene, encoding the potentially oncogenic metallothionein-2 (Si and Lang, 2018), was less expressed in Trp53 Eμ-Myc male pre-tumoral splenic cells, which raised the possibility of its direct or indirect repression by p53, potentially through the binding of p53 or the DREAM complex at its promoter (Engeland, 2018...

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PMC11615218

Summary of the Food and Drug Administration-approved CAR-T cell products.

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PMC11453018

The data represent mean ± SEM; p< 0.05, by one-way ANOVA (n=6).

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PMC6600592

Series of oxime-contained compounds with C6-C3 and C6-C4 skeleton were designed, synthesized, and assayed for anti-HBV activities.

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PMC10976516

In addition, studies with reovirus investigated how far these CCs might influence the balance of the ensuing antiviral vs. antitumor immune response.

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PMC10178190

In addition, our results corroborate previous findings, showing synergistic activity of Crizotinib and platinum compounds in animal models of OC .

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PMC11297139

The representative images supported by the relevant statistics have been chosen upon three independent preparations with similar outcomes.

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PMC11201989

Next, we assessed the effect of double knockdown of PD-L1 and BBS5 on PC-2 ciliary localization.

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PMC9388315

HSPs proteins participate in many processes such as angiogenesis, metastasis, and cancer cell metabolism .

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PMC8345486

Interestingly, unmodified nucleosides or the adenosine modified with the nido-7,8-dicarbaundecaborate ion were ineffective on cancer cell biology.

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PMC5916734

Similar data were obtained for FIX secreted by BHK cells .

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PMC11694066

They were further scaled to lie between 0 and 1.

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PMC11541409

C. Leaky activation.

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PMC9429973

They included fungi of the genus Candida – 6.5% (C. albicans – 5.4% (n=5), C. crusei – 1.1% (n=1)) and Rhodotorula spp. –

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PMC11697703

Titers of VSV-G pseudotyped viral particles were ∼10 IFUS/mL. Embryonic cortical cultures were prepared as previously described.

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PMC11283030

Qiang Liu: Writing – review & editing, Methodology, Investigation.

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PMC9429973

BCX9930 is an oral Factor D inhibitor that targets the rate-limiting enzyme of AP with the potential to prevent both intravascular hemolysis and extravascular hemolysis.

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PMC11723947

It was proposed that the SUMO E3 ligase PIAS1 negatively regulates Treg development by maintaining a repressive chromatin state at the Foxp3 promoter through the recruitment of HP1γ.

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PMC11367939

Sigma Plot version 10.0 (Systat Software Inc., San Jose, CA, USA), Origin 2022b (OriginLab Corporation, Northampton, MA, USA) and SPSS (IBM Corp., Armonk, NY, USA) were used for statistical analyses.

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PMC9429973

Results: Established anti-leukemic drugs exhibited only weak synergism with venetoclax in high-risk AML samples.

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PMC9684669

Statistical analysis was performed using a one-way ANOVA with Tukey’s HSD correction (*** p < 0.001). (

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PMC11321678

To investigate the chromatin accessibility heterogeneity in MBs, we performed scATAC‐seq (10X Genomics Chromium) on cells of frozen tumor tissues from 11 MB patients (Figure 1A; and Table S1, Supporting Information).

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PMC10899471

Moreover, this study also found that circulating miR-939-3p levels were higher in tumor patients than that in healthy individuals.

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PMC10849234

1000 ng of purified messenger RNA (mRNA) was reverse transcribed to complementary DNA (cDNA) using the 5x All-In-One RT Master Mix kit (abm).

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PMC9429973

Better understanding of the gut microbiome could provide actionable information in guiding precision medicine.

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PMC7369657

Statistically significant values were defined as p < 0.05 based on a two-tailed Student's t-test.

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PMC9429973

Responses deepened over time with an ORR of 86% among the pts with at least 10 months follow-up.

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PMC9429973

Cumulative incidence functions were used for CRS and ICANS resolution rates.

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PMC11674441

In this study, we retrospectively analysed the ability of our established neoantigen-pulsed DC (Neo-P DC) vaccine to induce an immune response in breast cancer patients.

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PMC3995603

RAW 264.7 cells were seeded at a density of 5×10 cells in a 48-well plate for the NO assay.

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PMC11247842

While GWAS identifies significant genetic markers, it is only the first step in the journey towards a comprehensive understanding of the underlying genetic mechanisms.

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PMC9429973

We propose a mechanism in which C/EBPα p30 mediates recruitment of TET2 to regulatory regions in the GATA2 gene to maintain its expression.

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PMC8010066

The overnight broth culture of Staphylococcus aureus ATCC25923 was adjusted to OD600:0.8.

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PMC11597291

Also, the GNR-4arm PEG system was evaluated on the inhibition and sonodynamic effect against ovarian cancer spheroids, resulting in reduced adhesion of the spheroids and reduced metastatic potential.

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PMC10587429

However, compared to clinical trials in human patients, our humanized model is only a fraction of the cost of a clinical trial.

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PMC11755519

Keyword combinations were selected for the search: ‘urinary bladder’ + ‘cancer’ + ‘development’/‘metastasis’ + ‘exosomes’/‘extracellular vesicles’.

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PMC10956161

Lung cancer is a malignant tumour that poses a serious threat to human health and its morbidity and mortality rates are among the highest in all cancers.

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PMC11413393

To better understand the observed cellular response to both MS023 treatment and the genetic knockdown of PRMT1, our next step was to profile transcriptomic changes via RNA-seq analysis in cell lines RCC243 and 786-0.

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PMC9429973

Radiological evidence for sclerotic lesions were found in 13 (81%) patients.

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PMC11732635

EBV is a widely prevalent herpes virus, with a global infection rate of around 95% (2).

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PMC9812014

Some of these compounds have IC50 concentrations lower than 5 µM and may prevent viral infections by more than 90 percent.

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PMC11697189

Clinical evaluation of the prognosis risk signature. (

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PMC9351137

From left to the right: DAPI (blue), anti-α-tubulin (green), cytokinesis regulators (red), and merge.

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PMC9596868

DMSO treated cells served as vehicle control in all experiments. (

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PMC7812570

Fig. 5Inhibitory activity of GPI-anchored antibodies in transduced human CD4+ T cells during HIV-1 infection.

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PMC11047729

Apart from ATRA, other substances also influence retinoic acid receptors: the novel retinoids, such as 9cUAB30, induce apoptosis and inhibit telomerase by down-regulating the hTERT gene in HL60 cells .

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PMC9370419

Next, we validated this conclusion by a Western blot assay (Figure 1K).

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PMC10204952

The respective seeding umber was 1 x 10 cells/well for MCF-12A, 1.5 x 10 cells/well for MDA-MB-231 and 2 x 10 cells/well for HCC1937.

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PMC11634794

Expression of LAMP1 in different tumor types in TIMER2.0 database (*P<0.05, **P<0.01, ***P<0.001).

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PMC10198699

As such, the present scenario would likely not be actionable by a present-day Henrietta Lacks.

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PMC11095939

Data are presented as means ± SEM; n = 3. ****

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