OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC11680562	Then, the preservatives (methylparaben, 0.1%) and 0.5 mL of glycerol were added to the gel (Fig. 2).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11675244	The “non-canonical” Wnt signaling, on the other hand, functions independently of β-catenin and involves pathways such as planar cell polarity, Wnt/Ca, protein kinase A, the c-Jun N-terminal cascade, and small GTPase signaling (RhoA, Rac1, and Cdc42) .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11036064	.	[ { "tags": [ "O" ], "tokens": [ "." ] } ]
PMC9219615	ERK is an extracellular signal-regulated kinase whose activation canonically enhances proliferation by controlling cell cycle progression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ERK", "is", "an", "extracellular", "signal-regulated", ...
PMC7987994	Vigorous shaking can lead to excessive abrasion of the material and increase the corrosion rate.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Vigorous", "shaking", "can", "lead", "to", "excessive", "ab...
PMC11750165	In the screen, where the reconstitution of the functional transcription factor of Gal4 DNA binding domain-bait fusion protein and prey-Gal4 activation domain fusion protein activates the LacZ reporter gene, 20 positive clones of 12 genes were identified by J2ICD from 60 million colonies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11593031	Firstly, we provide the first comprehensive cytogenomic analysis that highlights not only the near-tetraploid nature of the cell lines but also the specific chromosomal gains and losses that complicate their karyotypes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11695623	The effects of NDC1, DEPDC1 and CENPA on the prognosis of lung adenocarcinoma were further analyzed in TCGA database.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "effects", "of", ...
PMC11617590	Mia PaCa‐2 cells were seeded at 4 × 10 cells/3 mL/well and were treated for 24 h with sulforaphane (SFN) at concentrations of 0, 25, and 100 μM. Protein expression of BCL‐2, BAX, cleaved caspase 3, caspase 3, cleaved PARP, PARP, and GAPDH were measured using Western blot analysis.	[ { "tags": [ "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC11317131	After infection, host cells begin expressing the integrase protein from the SP.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "infection", ",", "host", "cells", "begin", "expressing", "the", ...
PMC9429973	A retrospective analysis of a cohort of 1563 patients enrolled from May 2020 to November 2020 was performed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "retrospective", "analysis", "of", ...
PMC11055510	Effects of circMAN1A2 overexpression on SKOV3 cell xenograft tumor volume. (	[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Effects", "of", "circMAN1A2", "overexpression", "on", "SKOV3", "cell", "xenograft", ...
PMC11066331	The grouping effect observed in Fig. 4A was reduced upon median centering of data (Fig. 4B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "grouping", "effect", "observed", ...
PMC9429973	References 1.	[ { "tags": [ "O", "O", "O" ], "tokens": [ "References", "1", "." ] } ]
PMC11371747	Drug exposure time: 72 h. IC50 values of growth inhibition of NSCLC and MPM cells by pemetrexed (PMX), pralatrexate (PLX) and raltitrexed (RTX) and corresponding protection by l-LV.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11604015	Normal T cells are generally a mixture of TRBC1 and TRBC2 T cells, while malignant T cells express only TRBC1 or TRBC2 on their surface, which enables TRBC1 or TRBC2 CAR-T cells to eliminate all relevant malignant T cells and only a subset of normal T cells .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9250505	Xenograft weight: mean xenograft weight of each treatment group after sacrifice on the 8th day.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Xenograft", "weight", ":", "mean", "xenograft", "weigh...
PMC11537649	MiR-152-3p was overexpressed in A375 cells. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O" ], "tokens": [ "MiR-152", "-", "3p", "was", "overexpressed", "in", "A375", "cells", ".", "(" ] } ]
PMC11138140	This analysis suggested that norepinephrine increases cardiomyocyte surface area as early as 10 h after treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "analysis", "suggested", "that", "norepinephrine", ...
PMC11806182	These findings suggest that these miRNAs may play a critical role in the heightened risk of developing UCEC in PCOS patients.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "findings", ...
PMC10443665	To separate the soluble and insoluble fractions, obtained gum dispersions were centrifuged at 16000 rpm for 15 min.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "separate", "the", "soluble"...
PMC11678130	To achieve this goal, the current research proposed an in vitro investigation of the efficacy of the combination therapy between quercetin (QUE) and 5-FU as a potential strategy in CM treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11310713	Hormone production is one of the paramount roles of the ovary as a reproductive organ in females.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Hormone", "production", "is", "one", "of", ...
PMC10747139	Interestingly, BOLD-100 has demonstrated activity against SARS-CoV-2, HIV-1, and human adenovirus type 5.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Interestingly", ",", "BOLD-100", "has", "demonstrated", ...
PMC11604830	time = 2 min 46 s), water suppression scheme = VAPOR, water suppression bandwidth = 400 Hz.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "time", "=", "2", "min"...
PMC10734950	A cell in the process of apoptosis can follow through either the intrinsic or extrinsic pathway .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "cell", "in", "the", "process", "of", "apopt...
PMC11352746	IncuCyte NucLight Rapid Red Reagent (EssenBioScience Ann Arbor, MI, USA, Cat.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "IncuCyte", "NucLight", "Rapid", "Red", "Reagent", "(", "Ess...
PMC10040136	All experiments were repeated at least thrice.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "experiments", "were", "repeated", "at", "least", "thrice", "." ] } ]
PMC11093197	c‐Myc is one of the critical ERK substrates in the cell cycle progression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "c‐Myc", "is", "one", "of", "the", "critical", "ERK", "substrates", "i...
PMC9429973	Discharge shortly after HIDAC was possible in 45 cycles (67.5%) and no readmission was required in 14 (20.9%).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11297139	These studies suggest the possibility that ARID1A plays a critical role in regulating oncogenesis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "studies", "suggest", "the", "possibility", "that", "ARID1A", ...
PMC9429973	Subsequently, transfer of mononuclear cell suspension (bone marrow + spleen) from Balb / c mice into CB6F1 mice irradiated with 60co X-ray via tail vein injection.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11796104	We previously identified expression profiles of mRNA in male osteoporosis by RNA-sequencing and bioinformatics analysis .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "previously", "identified", "expression", "profiles", "of", ...
PMC2193049	The peak corresponding to the 7-mer MAGE-3272–278 (812 daltons) was not detectable in the sample incubated with the proteasome inhibitor.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "peak"...
PMC11621493	Differential expression between KO and WT cells is visualized in a heat map, displaying the z-score.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Differential", "expression", "between", "KO", "an...
PMC5963610	This dose has been previously shown to deplete more than 98% of the cell subset.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "dose", "has", "been", "previously", "shown", ...
PMC7812570	2Effects of GPI-anchored antibodies on the expression of HIV receptors.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "2Effects", "of", "GPI-anchored", "antibodies", "on", "the", "expression", "of", "HIV", "receptor...
PMC10024132	After genetic engineering, our blinatumomab-secreting γ9δ2 T cells induced significant cytotoxicity in CD19 ALL cell lines and primary cells from CLL patients.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After",...
PMC11650848	There is no comparable RCT cohort looking at cognitive outcomes in children following folic acid supplementation in later pregnancy to which it can be properly compared, although there is some support for improvements in language development and cognitive outcomes from observational cohorts [81–84].	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11604768	Amplicons were quantified with the KAPA Library Quantification Kit for Illumina Platforms (KAPA Biosystems) in 384-well format using a CFX Opus 384-Well Real-Time System (Bio-Rad).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11562028	The displayed data were in a two-dimensional format, and each value represented a matrix of upregulated (red) and downregulated (blue) genes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11541409	KIT functions as a receptor for an extracellular ligand (SCF) and as an enzyme (kinase) that catalyzes the transfer of a phosphate group from ATP to tyrosine residues on KIT and downstream proteins.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9143157	However, by the present treatment protocol, no advantage was observed for P-THP than free THP in the DOX-resistant A2780/ADR tumor model (Figure 3F), as both P-THP and THP did not show a significant antitumor effect.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", ...
PMC11727145	Imaging was performed with an Olympus IX81 microscope (Olympus Corporation, Tokyo, Japan; Figure 1C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Imaging", "was", "performed", "wi...
PMC10887351	Originally, the attention was largely focused on β2-ARs , but recently, the β3-AR over-expression was found in melanoma cell lines and TME .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11529598	MiR-3154 is a newly discovered miRNA which has been identified as prognostic biomarker for cervical cancer .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "MiR-3154", "is", "a", "newly", "discovered", "miRNA", ...
PMC11618052	Yield: 0.26 g (70%), white solid, m.p: 158–160 °C, Rf.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Yield", ":", "0.26", "g", "...
PMC11768281	Th1 cells are considered superior in malaria protection due to their intracellular mechanisms of Plasmodium.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Th1", "cells", "are", "considered", "superior", "in", "mala...
PMC11786704	H–I) CLSM images of the ROS scavenging capacity in RAW 264.7 and DC2.4 cells using DCFH-DA probe, with the quantitative results of DCF fluorescence intensity in (J–K). (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O"...
PMC7553912	Oncostatin M (OSM), a member of the IL-6 family of cytokines, has important roles in renal diseases.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Oncostatin", "M", ...
PMC10114490	Wells containing cells were expanded and GFP-positive clones, after a 48-h Dox pulse, stocked in liquid nitrogen.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Wells", "containing", "cells", "w...
PMC11442172	Importantly, the metabolites that exhibited significant changes were primarily associated with purine and pyrimidine metabolism, consistent with the known mechanism of action of 5-FU (63).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11594588	Autopsies were performed on 63 patients with clinically definite or possible acute myocardial infarction (AMI) .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Autopsies", "were", "performed", "on", "63", ...
PMC11519077	The Caco-2 cell line was grown on six-well cell culture plates with a density of 80,000 cells per well for coculture.	[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "Caco-2"...
PMC9429973	Whilst our ORR is lower than those published in trial data on commonly used regimens (78% vs MCL Younger trial ORR: RCHOP arm 90%/Cytarabine arm 94%) our cohort’s baseline demographics are comparably much higher risk: MIPIb High 53% vs 25/20%; Blastoid disease 25% vs 9/8%.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10976516	Lung cancer is typically asymptomatic in its early stages, and this is one of the main reasons why most lung cancer patients are diagnosed relatively late with stage III or stage IV.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11768927	VSV exploits these defects, selectively targeting and lysing cancer cells while sparing normal tissues.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "VSV", "exploits", "these", "defects", ",", "selectively", "...
PMC8494202	Expression of CKAP2L was measured in all five cell lines, as described below, and the cell line with the highest CKAP2L expression was selected for further experiments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6934009	The formation of acidic autophagic vacuoles was found to increase significantly in A427 cells on treatment with 25, 30, and 50 µM doses of wogonin for 72 h. Moreover, the treatment with wogonin enhanced the expression of LC3II in these cells in a dose-dependent manner (Figure 6B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Nephrotic syndrome was present in 19 (82%) group №1 patients, nephrotic syndrome was 2 times less frequent in group №2 (10 (38%) patients, p=0,001).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11743316	CRL4 can modulate OC cell's chemoresistance by modulating the dynamics of mitochondria and mitophagy, and CRL4 inhibition suppresses the proliferation of chemoresistant ovarian cancer through triggering mitophagy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Aims: To assess safety and response to venetoclax + hypomethylation agent + low-dose cytarabine regimen after minimum 1 cycle of therapy in patients with AML or MDS, who developed morphologic or molecular relapse, or had refractory disease or persistent positive minimal residual disease (MRD) at the end of consolidatio...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	MTD has not been reached.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "MTD", "has", "not", "been", "reached", "." ] } ]
PMC4816271	Lan-1 and A204 cells were cultivated in IMDM supplemented with 10% FCS and L-Glutamine.	[ { "tags": [ "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Lan-1", "and", "A204", "cells", "were", "cultiv...
PMC9268620	Therefore, we report here that nordamnacanthal and damnacanthal induced apoptosis cell death to CEM-SS cells, but the downstream mechanism that leads to this needs to be explored further.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11461874	A representative result of two independent experiments is shown.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "representative", "result", "of", "two", "independent", "experiments", "is", "shown", "." ] } ]
PMC5417661	For example, the therapeutic effects of existing drugs may be enhanced by combining them with the next generation Pgp inhibitors under development.14 Alternatively, adjustment of the clinical concentration of the drug-of-choice to counteract the kinetic parameters of Pgp-mediated efflux can improve the therapy outcome....	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8540692	All the experiments were repeated three times with four measurements per assay.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "the", "experiments", "were", "repeated", "three", "times", "with", "four"...
PMC11672881	A375, HDFa, and HaCaT were treated with serial dosages of CU (2.5 to 50 µM) and TQ (5 to 80 µM) individually and their combination for 24 h to determine growth inhibitory effects using the AlamarBlue assay (Figure 1).	[ { "tags": [ "B-CellLine", "O", "B-CellLine", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"...
PMC10547921	The SAR showed that hydroxyl substitution of C-10 could enhance the anti-tumor activity of CPT, and the dissubstitution of C-7 and C-10 could stabilize the lactone ring and improve the molecular biological activity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11321678	Based on the above results, we nominated the cluster‐specific driver TFs (Figure 3D,E).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Based", "on", "the", "above", "results...
PMC11767725	Reduced perfusion also delays the clearance of metabolic byproducts and toxins, further modifying the microbial habitat .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Reduced", "perfusion", "also", "delays", "the", ...
PMC11806818	In addition, the low abundance and complex composition of tumor-associated exosomes in biological samples hinder the clinical application of exosome-based cancer diagnosis .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", ...
PMC10729469	As a first step for transduction, the lentiviral approach was used to facilitate TCRAβ entry into TCR-Tregs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "As", "a", "first", "step", "for", ...
PMC7602170	GIST patients with KIT exon 9 mutations had a significantly worse prognosis compared to those with KIT exon 11 mutations , who also exhibited worse response to imatinib treatment .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11687167	B Structure domains of human PCSK9.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "B", "Structure", "domains", "of", "human", "PCSK9", "." ] } ]
PMC8427838	Interestingly, there were also markedly high levels of actin on the periphery of 786-0 cells expressing TMIGD1 (Fig. 5D).Fig.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O" ], ...
PMC11683240	After the separation, the column was reequilibrated with two column volumes of 95% A and 5% B. Aliquots representing one percent of every chromatographic fraction were sampled in deep well microtiter tubes in a 96-well format using a pipetting robot, then lyophilized and stored at −20 °C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11552389	Melanoma cell proliferation, invasion, and migration were assessed using the colony formation assay, the scratch wound healing test, the Transwell invasion assay, and the nude mice xenograft to determine the effects of FOXN3 over-expression and depletion.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11730311	Comparison of Schild slopes showed that hαCGRP8-37A36S, N25K-C20DA-γGlu displayed a significantly higher Schild slope than hαCGRP8-37 (1.83 ± 0.63 vs 0.94 ± 0.15, p < 0.001), hαCGRP8-37A36S (1.83 ± 0.63 vs 1.08 ± 0.23, p = 0.003), and hαCGRP8-37N25K-C20DA-γGlu (1.83 ± 0.63 vs 0.94 ± 0.15, p < 0.001).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11525028	Dot plot showing the inhibitory efficiency of proliferation and migration of each siRNA.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Dot", "plot", "showing", "the", "inhibitory", "efficiency", "of", "prolifer...
PMC9429973	Aims: We sought to evaluate whether germline ATM variants are more frequent in chronic lymphocytic leukemia (CLL) compared to other hematologic malignancies and whether they influence the clinical characteristics of CLL.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10291556	Importantly, the in vivo activity of Pt(II) complex 1 was significantly improved by its oxidation to the platinum(IV) analogue.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Importantly", ...
PMC9429973	These results may be improved by the assessment of the response by PET-CT, using more intensified regimens and the availability of ASCT especially in high-risk patients and in patients who achieved only PR.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11792888	The fractionation procedure was performed by injecting 6 mg of the venom dissolved in water and was eluted at 1 mL/min flow rate using a linear gradient of 0-45% of solvent B for 45 min, then increased linearly to 100% solvent.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11513011	Bladder cancer is divided into non-muscle invasive and invasive types, and treatment differs greatly between the two types.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Bladder", "cancer", "is", "divide...
PMC7369657	After 24, 48, and 72 h exposure to CQDs, the supernatant was collected from individual wells and centrifuged.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "24", ","...
PMC10033453	Injections were repeated at days 5 and 10.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Injections", "were", "repeated", "at", "days", "5", "and", "10", "." ] } ]
PMC10142392	The use of nanocarriers for drug delivery may be a promising strategy to effectively treat certain diseases.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "use", "of", "nanocarriers", "for", "...
PMC5874706	The α-cyclodextrins were purchased from Roquette Frères (Lestrem, France) and their modification to amphiphilic CDs (Figure 2) was conducted according to the syntheses described previously by our group .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8922418	As we and others have found that some point mutations (S532, T534, T536, L537A/W666A, and I535A/V539G) in the HIV-1 gp41 region significantly reduced or blocked Env-mediated syncytium formation and affected viral fusion and infection, these residues could be targeted by base editors for generating dead-virus without in...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11683240	Hence, while α1AT administration reduced B. pertussis-induced leukocytosis but failed to protect against B. pertussis-induced airway pathology in the study presented here, we cannot rule out the potential for higher doses of α1AT to ameliorate this phenotype.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6222635	The extract was precipitated with 80% ethanol to obtain the polysaccharides.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "extract", "was", "precipitated", "with", "80", "%", "ethanol", "to", ...
PMC11633763	C, D) Western blotting and qRT‐PCR analyses of HK2 expression levels in U2OS cells stably transfected with control vector or p‐USP22 plasmid. *	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ],...
PMC11680562	Cell viability was calculated using Eq. (1) .1[12pt] $$\% } = \, ( / \, OD \, c_ } ) \, 00$$%Viability=ODtreatedcells/ODcontrol×100 Mean OD treated cells = absorbance of the treated cells, while Mean ODcontrol = absorbance of the control .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11306331	In sum, the OptoMBP system provides a step towards programmable, optogenetic dissolution of biomolecular condensates.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "sum", ",", "the", "OptoMBP", "system"...
PMC6337547	It mainly contributed to intensely and selectively suppressing the expression of cyclooxygenase (COX)-2 and balancing the ratio of thromboxane A2 (TXA2)/prostacyclin (PGI2) .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11759751	Apoptosis was assessed using the Annexin V/7-AAD apoptosis assay kit (BD Biosciences, USA), with the apoptosis rate determined by flow cytometry following cell staining.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11759543	In the combination of doxorubicin and vorinostat, it activates caspase 8-casepase3-apoptosis pathway to induce cell death.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "the", "combination", "of", "doxorubicin", ...
PMC10898159	Limb Expression 1 (LIX1) is a unique marker of digestive mesenchyme immaturity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Limb", "Expression", "1", "(", "LIX1", ")", "is", "a", "un...

PMC11680562

Then, the preservatives (methylparaben, 0.1%) and 0.5 mL of glycerol were added to the gel (Fig. 2).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC11675244

The “non-canonical” Wnt signaling, on the other hand, functions independently of β-catenin and involves pathways such as planar cell polarity, Wnt/Ca, protein kinase A, the c-Jun N-terminal cascade, and small GTPase signaling (RhoA, Rac1, and Cdc42) .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11036064

.

[ { "tags": [ "O" ], "tokens": [ "." ] } ]

PMC9219615

ERK is an extracellular signal-regulated kinase whose activation canonically enhances proliferation by controlling cell cycle progression.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ERK", "is", "an", "extracellular", "signal-regulated", ...

PMC7987994

Vigorous shaking can lead to excessive abrasion of the material and increase the corrosion rate.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Vigorous", "shaking", "can", "lead", "to", "excessive", "ab...

PMC11750165

In the screen, where the reconstitution of the functional transcription factor of Gal4 DNA binding domain-bait fusion protein and prey-Gal4 activation domain fusion protein activates the LacZ reporter gene, 20 positive clones of 12 genes were identified by J2ICD from 60 million colonies.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11593031

Firstly, we provide the first comprehensive cytogenomic analysis that highlights not only the near-tetraploid nature of the cell lines but also the specific chromosomal gains and losses that complicate their karyotypes.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11695623

The effects of NDC1, DEPDC1 and CENPA on the prognosis of lung adenocarcinoma were further analyzed in TCGA database.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "effects", "of", ...

PMC11617590

Mia PaCa‐2 cells were seeded at 4 × 10 cells/3 mL/well and were treated for 24 h with sulforaphane (SFN) at concentrations of 0, 25, and 100 μM. Protein expression of BCL‐2, BAX, cleaved caspase 3, caspase 3, cleaved PARP, PARP, and GAPDH were measured using Western blot analysis.

[ { "tags": [ "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...

PMC11317131

After infection, host cells begin expressing the integrase protein from the SP.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "infection", ",", "host", "cells", "begin", "expressing", "the", ...

PMC9429973

A retrospective analysis of a cohort of 1563 patients enrolled from May 2020 to November 2020 was performed.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "retrospective", "analysis", "of", ...

PMC11055510

Effects of circMAN1A2 overexpression on SKOV3 cell xenograft tumor volume. (

[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Effects", "of", "circMAN1A2", "overexpression", "on", "SKOV3", "cell", "xenograft", ...

PMC11066331

The grouping effect observed in Fig. 4A was reduced upon median centering of data (Fig. 4B).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "grouping", "effect", "observed", ...

PMC9429973

References 1.

[ { "tags": [ "O", "O", "O" ], "tokens": [ "References", "1", "." ] } ]

PMC11371747

Drug exposure time: 72 h. IC50 values of growth inhibition of NSCLC and MPM cells by pemetrexed (PMX), pralatrexate (PLX) and raltitrexed (RTX) and corresponding protection by l-LV.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11604015

Normal T cells are generally a mixture of TRBC1 and TRBC2 T cells, while malignant T cells express only TRBC1 or TRBC2 on their surface, which enables TRBC1 or TRBC2 CAR-T cells to eliminate all relevant malignant T cells and only a subset of normal T cells .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9250505

Xenograft weight: mean xenograft weight of each treatment group after sacrifice on the 8th day.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Xenograft", "weight", ":", "mean", "xenograft", "weigh...

PMC11537649

MiR-152-3p was overexpressed in A375 cells. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O" ], "tokens": [ "MiR-152", "-", "3p", "was", "overexpressed", "in", "A375", "cells", ".", "(" ] } ]

PMC11138140

This analysis suggested that norepinephrine increases cardiomyocyte surface area as early as 10 h after treatment.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "analysis", "suggested", "that", "norepinephrine", ...

PMC11806182

These findings suggest that these miRNAs may play a critical role in the heightened risk of developing UCEC in PCOS patients.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "findings", ...

PMC10443665

To separate the soluble and insoluble fractions, obtained gum dispersions were centrifuged at 16000 rpm for 15 min.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "separate", "the", "soluble"...

PMC11678130

To achieve this goal, the current research proposed an in vitro investigation of the efficacy of the combination therapy between quercetin (QUE) and 5-FU as a potential strategy in CM treatment.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11310713

Hormone production is one of the paramount roles of the ovary as a reproductive organ in females.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Hormone", "production", "is", "one", "of", ...

PMC10747139

Interestingly, BOLD-100 has demonstrated activity against SARS-CoV-2, HIV-1, and human adenovirus type 5.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Interestingly", ",", "BOLD-100", "has", "demonstrated", ...

PMC11604830

time = 2 min 46 s), water suppression scheme = VAPOR, water suppression bandwidth = 400 Hz.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "time", "=", "2", "min"...

PMC10734950

A cell in the process of apoptosis can follow through either the intrinsic or extrinsic pathway .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "cell", "in", "the", "process", "of", "apopt...

PMC11352746

IncuCyte NucLight Rapid Red Reagent (EssenBioScience Ann Arbor, MI, USA, Cat.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "IncuCyte", "NucLight", "Rapid", "Red", "Reagent", "(", "Ess...

PMC10040136

All experiments were repeated at least thrice.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "experiments", "were", "repeated", "at", "least", "thrice", "." ] } ]

PMC11093197

c‐Myc is one of the critical ERK substrates in the cell cycle progression.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "c‐Myc", "is", "one", "of", "the", "critical", "ERK", "substrates", "i...

PMC9429973

Discharge shortly after HIDAC was possible in 45 cycles (67.5%) and no readmission was required in 14 (20.9%).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC11297139

These studies suggest the possibility that ARID1A plays a critical role in regulating oncogenesis.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "studies", "suggest", "the", "possibility", "that", "ARID1A", ...

PMC9429973

Subsequently, transfer of mononuclear cell suspension (bone marrow + spleen) from Balb / c mice into CB6F1 mice irradiated with 60co X-ray via tail vein injection.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11796104

We previously identified expression profiles of mRNA in male osteoporosis by RNA-sequencing and bioinformatics analysis .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "previously", "identified", "expression", "profiles", "of", ...

PMC2193049

The peak corresponding to the 7-mer MAGE-3272–278 (812 daltons) was not detectable in the sample incubated with the proteasome inhibitor.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "peak"...

PMC11621493

Differential expression between KO and WT cells is visualized in a heat map, displaying the z-score.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Differential", "expression", "between", "KO", "an...

PMC5963610

This dose has been previously shown to deplete more than 98% of the cell subset.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "dose", "has", "been", "previously", "shown", ...

PMC7812570

2Effects of GPI-anchored antibodies on the expression of HIV receptors.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "2Effects", "of", "GPI-anchored", "antibodies", "on", "the", "expression", "of", "HIV", "receptor...

PMC10024132

After genetic engineering, our blinatumomab-secreting γ9δ2 T cells induced significant cytotoxicity in CD19 ALL cell lines and primary cells from CLL patients.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After",...

PMC11650848

There is no comparable RCT cohort looking at cognitive outcomes in children following folic acid supplementation in later pregnancy to which it can be properly compared, although there is some support for improvements in language development and cognitive outcomes from observational cohorts [81–84].

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11604768

Amplicons were quantified with the KAPA Library Quantification Kit for Illumina Platforms (KAPA Biosystems) in 384-well format using a CFX Opus 384-Well Real-Time System (Bio-Rad).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11562028

The displayed data were in a two-dimensional format, and each value represented a matrix of upregulated (red) and downregulated (blue) genes.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...

PMC11541409

KIT functions as a receptor for an extracellular ligand (SCF) and as an enzyme (kinase) that catalyzes the transfer of a phosphate group from ATP to tyrosine residues on KIT and downstream proteins.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9143157

However, by the present treatment protocol, no advantage was observed for P-THP than free THP in the DOX-resistant A2780/ADR tumor model (Figure 3F), as both P-THP and THP did not show a significant antitumor effect.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", ...

PMC11727145

Imaging was performed with an Olympus IX81 microscope (Olympus Corporation, Tokyo, Japan; Figure 1C).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Imaging", "was", "performed", "wi...

PMC10887351

Originally, the attention was largely focused on β2-ARs , but recently, the β3-AR over-expression was found in melanoma cell lines and TME .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC11529598

MiR-3154 is a newly discovered miRNA which has been identified as prognostic biomarker for cervical cancer .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "MiR-3154", "is", "a", "newly", "discovered", "miRNA", ...

PMC11618052

Yield: 0.26 g (70%), white solid, m.p: 158–160 °C, Rf.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Yield", ":", "0.26", "g", "...

PMC11768281

Th1 cells are considered superior in malaria protection due to their intracellular mechanisms of Plasmodium.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Th1", "cells", "are", "considered", "superior", "in", "mala...

PMC11786704

H–I) CLSM images of the ROS scavenging capacity in RAW 264.7 and DC2.4 cells using DCFH-DA probe, with the quantitative results of DCF fluorescence intensity in (J–K). (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O"...

PMC7553912

Oncostatin M (OSM), a member of the IL-6 family of cytokines, has important roles in renal diseases.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Oncostatin", "M", ...

PMC10114490

Wells containing cells were expanded and GFP-positive clones, after a 48-h Dox pulse, stocked in liquid nitrogen.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Wells", "containing", "cells", "w...

PMC11442172

Importantly, the metabolites that exhibited significant changes were primarily associated with purine and pyrimidine metabolism, consistent with the known mechanism of action of 5-FU (63).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11594588

Autopsies were performed on 63 patients with clinically definite or possible acute myocardial infarction (AMI) .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Autopsies", "were", "performed", "on", "63", ...

PMC11519077

The Caco-2 cell line was grown on six-well cell culture plates with a density of 80,000 cells per well for coculture.

[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "Caco-2"...

PMC9429973

Whilst our ORR is lower than those published in trial data on commonly used regimens (78% vs MCL Younger trial ORR: RCHOP arm 90%/Cytarabine arm 94%) our cohort’s baseline demographics are comparably much higher risk: MIPIb High 53% vs 25/20%; Blastoid disease 25% vs 9/8%.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10976516

Lung cancer is typically asymptomatic in its early stages, and this is one of the main reasons why most lung cancer patients are diagnosed relatively late with stage III or stage IV.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11768927

VSV exploits these defects, selectively targeting and lysing cancer cells while sparing normal tissues.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "VSV", "exploits", "these", "defects", ",", "selectively", "...

PMC8494202

Expression of CKAP2L was measured in all five cell lines, as described below, and the cell line with the highest CKAP2L expression was selected for further experiments.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC6934009

The formation of acidic autophagic vacuoles was found to increase significantly in A427 cells on treatment with 25, 30, and 50 µM doses of wogonin for 72 h. Moreover, the treatment with wogonin enhanced the expression of LC3II in these cells in a dose-dependent manner (Figure 6B).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Nephrotic syndrome was present in 19 (82%) group №1 patients, nephrotic syndrome was 2 times less frequent in group №2 (10 (38%) patients, p=0,001).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11743316

CRL4 can modulate OC cell's chemoresistance by modulating the dynamics of mitochondria and mitophagy, and CRL4 inhibition suppresses the proliferation of chemoresistant ovarian cancer through triggering mitophagy.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Aims: To assess safety and response to venetoclax + hypomethylation agent + low-dose cytarabine regimen after minimum 1 cycle of therapy in patients with AML or MDS, who developed morphologic or molecular relapse, or had refractory disease or persistent positive minimal residual disease (MRD) at the end of consolidatio...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

MTD has not been reached.

[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "MTD", "has", "not", "been", "reached", "." ] } ]

PMC4816271

Lan-1 and A204 cells were cultivated in IMDM supplemented with 10% FCS and L-Glutamine.

[ { "tags": [ "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Lan-1", "and", "A204", "cells", "were", "cultiv...

PMC9268620

Therefore, we report here that nordamnacanthal and damnacanthal induced apoptosis cell death to CEM-SS cells, but the downstream mechanism that leads to this needs to be explored further.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11461874

A representative result of two independent experiments is shown.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "representative", "result", "of", "two", "independent", "experiments", "is", "shown", "." ] } ]

PMC5417661

For example, the therapeutic effects of existing drugs may be enhanced by combining them with the next generation Pgp inhibitors under development.14 Alternatively, adjustment of the clinical concentration of the drug-of-choice to counteract the kinetic parameters of Pgp-mediated efflux can improve the therapy outcome....

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8540692

All the experiments were repeated three times with four measurements per assay.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "the", "experiments", "were", "repeated", "three", "times", "with", "four"...

PMC11672881

A375, HDFa, and HaCaT were treated with serial dosages of CU (2.5 to 50 µM) and TQ (5 to 80 µM) individually and their combination for 24 h to determine growth inhibitory effects using the AlamarBlue assay (Figure 1).

[ { "tags": [ "B-CellLine", "O", "B-CellLine", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"...

PMC10547921

The SAR showed that hydroxyl substitution of C-10 could enhance the anti-tumor activity of CPT, and the dissubstitution of C-7 and C-10 could stabilize the lactone ring and improve the molecular biological activity.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11321678

Based on the above results, we nominated the cluster‐specific driver TFs (Figure 3D,E).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Based", "on", "the", "above", "results...

PMC11767725

Reduced perfusion also delays the clearance of metabolic byproducts and toxins, further modifying the microbial habitat .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Reduced", "perfusion", "also", "delays", "the", ...

PMC11806818

In addition, the low abundance and complex composition of tumor-associated exosomes in biological samples hinder the clinical application of exosome-based cancer diagnosis .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", ...

PMC10729469

As a first step for transduction, the lentiviral approach was used to facilitate TCRAβ entry into TCR-Tregs.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "As", "a", "first", "step", "for", ...

PMC7602170

GIST patients with KIT exon 9 mutations had a significantly worse prognosis compared to those with KIT exon 11 mutations , who also exhibited worse response to imatinib treatment .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11687167

B Structure domains of human PCSK9.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "B", "Structure", "domains", "of", "human", "PCSK9", "." ] } ]

PMC8427838

Interestingly, there were also markedly high levels of actin on the periphery of 786-0 cells expressing TMIGD1 (Fig. 5D).Fig.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O" ], ...

PMC11683240

After the separation, the column was reequilibrated with two column volumes of 95% A and 5% B. Aliquots representing one percent of every chromatographic fraction were sampled in deep well microtiter tubes in a 96-well format using a pipetting robot, then lyophilized and stored at −20 °C.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11552389

Melanoma cell proliferation, invasion, and migration were assessed using the colony formation assay, the scratch wound healing test, the Transwell invasion assay, and the nude mice xenograft to determine the effects of FOXN3 over-expression and depletion.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11730311

Comparison of Schild slopes showed that hαCGRP8-37A36S, N25K-C20DA-γGlu displayed a significantly higher Schild slope than hαCGRP8-37 (1.83 ± 0.63 vs 0.94 ± 0.15, p < 0.001), hαCGRP8-37A36S (1.83 ± 0.63 vs 1.08 ± 0.23, p = 0.003), and hαCGRP8-37N25K-C20DA-γGlu (1.83 ± 0.63 vs 0.94 ± 0.15, p < 0.001).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11525028

Dot plot showing the inhibitory efficiency of proliferation and migration of each siRNA.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Dot", "plot", "showing", "the", "inhibitory", "efficiency", "of", "prolifer...

PMC9429973

Aims: We sought to evaluate whether germline ATM variants are more frequent in chronic lymphocytic leukemia (CLL) compared to other hematologic malignancies and whether they influence the clinical characteristics of CLL.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10291556

Importantly, the in vivo activity of Pt(II) complex 1 was significantly improved by its oxidation to the platinum(IV) analogue.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Importantly", ...

PMC9429973

These results may be improved by the assessment of the response by PET-CT, using more intensified regimens and the availability of ASCT especially in high-risk patients and in patients who achieved only PR.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11792888

The fractionation procedure was performed by injecting 6 mg of the venom dissolved in water and was eluted at 1 mL/min flow rate using a linear gradient of 0-45% of solvent B for 45 min, then increased linearly to 100% solvent.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11513011

Bladder cancer is divided into non-muscle invasive and invasive types, and treatment differs greatly between the two types.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Bladder", "cancer", "is", "divide...

PMC7369657

After 24, 48, and 72 h exposure to CQDs, the supernatant was collected from individual wells and centrifuged.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "24", ","...

PMC10033453

Injections were repeated at days 5 and 10.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Injections", "were", "repeated", "at", "days", "5", "and", "10", "." ] } ]

PMC10142392

The use of nanocarriers for drug delivery may be a promising strategy to effectively treat certain diseases.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "use", "of", "nanocarriers", "for", "...

PMC5874706

The α-cyclodextrins were purchased from Roquette Frères (Lestrem, France) and their modification to amphiphilic CDs (Figure 2) was conducted according to the syntheses described previously by our group .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8922418

As we and others have found that some point mutations (S532, T534, T536, L537A/W666A, and I535A/V539G) in the HIV-1 gp41 region significantly reduced or blocked Env-mediated syncytium formation and affected viral fusion and infection, these residues could be targeted by base editors for generating dead-virus without in...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11683240

Hence, while α1AT administration reduced B. pertussis-induced leukocytosis but failed to protect against B. pertussis-induced airway pathology in the study presented here, we cannot rule out the potential for higher doses of α1AT to ameliorate this phenotype.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC6222635

The extract was precipitated with 80% ethanol to obtain the polysaccharides.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "extract", "was", "precipitated", "with", "80", "%", "ethanol", "to", ...

PMC11633763

C, D) Western blotting and qRT‐PCR analyses of HK2 expression levels in U2OS cells stably transfected with control vector or p‐USP22 plasmid. *

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ],...

PMC11680562

Cell viability was calculated using Eq. (1) .1[12pt] $$\% } = \, ( / \, OD \, c_ } ) \, 00$$%Viability=ODtreatedcells/ODcontrol×100 Mean OD treated cells = absorbance of the treated cells, while Mean ODcontrol = absorbance of the control .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11306331

In sum, the OptoMBP system provides a step towards programmable, optogenetic dissolution of biomolecular condensates.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "sum", ",", "the", "OptoMBP", "system"...

PMC6337547

It mainly contributed to intensely and selectively suppressing the expression of cyclooxygenase (COX)-2 and balancing the ratio of thromboxane A2 (TXA2)/prostacyclin (PGI2) .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC11759751

Apoptosis was assessed using the Annexin V/7-AAD apoptosis assay kit (BD Biosciences, USA), with the apoptosis rate determined by flow cytometry following cell staining.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11759543

In the combination of doxorubicin and vorinostat, it activates caspase 8-casepase3-apoptosis pathway to induce cell death.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "the", "combination", "of", "doxorubicin", ...

PMC10898159

Limb Expression 1 (LIX1) is a unique marker of digestive mesenchyme immaturity.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Limb", "Expression", "1", "(", "LIX1", ")", "is", "a", "un...