OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC9352806	Bitter melon (Momordica charantia L.) is recognized as a medicinal and edible plant for obesity and diabetes prevention due to its numerous active ingredients, like polysaccharides, saponins, peptides or flavonoids (Bai et al., 2018).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7612475	RNAseH1 induction in these cells did not alter sensitivity to olaparib or etoposide, indicating that the induction of DNA damage, and subsequent DNA repair and cellular survival following treatment with these agents, is not dependent on R-loops (Supplementary Fig. S4D).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7762347	The cDNA High Capacity Archive Kit, Taqman Gene Expression Assays, and Taqman Universal PCR Master Mix were purchased from Applied Biosystems (Waltham, MA, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9250505	No significant differences were observed in the percentage of BAD-positive cells between the different treatment groups.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "No", "significant", "differences", "were", "observed", ...
PMC11052306	Four dendrons (7a-G1, 7b-G1, 8a-G1, and 8b-G1) were active against the HCT116 cell line at a concentration of 10 M but not at 10 M. These four dendrons were then tested with the non-cancerous RPE1 cells and were deceptively found to be even more toxic, as shown in Figure 10.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11543853	Inhibiting post-endocytic membrane remodeling with wiskostatin promoted abortive enterovirus genome release in endosomes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Inhibiting", "post-endocytic", "membrane", "remodeling", "with", "wiskostatin", "...
PMC11747949	PD‐L1 expression decreased in hypoxia and in transwell assay (Figure 1D,E).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "PD‐L1", "expression", "decreased", "in", "hypoxia", "and", ...
PMC9429973	Median follow-up was 61.5 months (IQR 49.7 – 72.9 months).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Median", "follow-up", "was", "61.5", "months", "(", "IQR", "49.7", "–", "7...
PMC11755519	These results indicate that activation of Akt and ERK pathways may be involved in the exosome-stimulated proliferation of bladder cancer cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "results", ...
PMC8633974	Targeted HIV-1 gene therapy requires specific recognition of diverse proviral sequences.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Targeted", "HIV-1", "gene", "therapy", "requires", "specific", "recognition", "of", "divers...
PMC8469018	Hoestch 33342 (Thermo Fisher Scientific, Waltham, MA, USA) and MitoTracker Green FM (Thermo Fisher Scientific, Waltham, USA) were used to control fractionation quality.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11237030	AQP5 expression stability over-time.	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "AQP5", "expression", "stability", "over-time", "." ] } ]
PMC11682172	Data representative of three independent experiments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "representative", "of", "three", "independent", "experiments", "." ] } ]
PMC11714165	On the other hand, activated osteoclasts secrete calcium ions, insulin like growth factors (IGFs) and transforming growth factor‐β (TGF‐β), which promote osteosarcoma cell proliferation and invasion.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11739484	P-value < 0.05.	[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "P-value", "<", "0.05", "." ] } ]
PMC11391695	However, si-ACYP2 + si-TERT treatment restored these properties in SMMC-7721 and BEL-7404 cells (Fig. 4F, Fig. S5B, D).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens"...
PMC7802142	After incubation with HRP-conjugated secondary antibodies, the signals were visualized using ECL Substrates (Bio-Rad).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "incubation", "with", "HRP-conjugated", "...
PMC11774251	Topical applications were administered daily for 6 days, with the experiment ending on day 7.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Topical", "applications", "were", "administered", "daily", ...
PMC11686380	First, unstable variant GAP43 can be still functional, and may have a protective effect to ameliorate morphological abnormalities.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "First", ",", "unstable", ...
PMC9429973	Our findings show that PDIA3, BTN1A1, APRIL and complement proteins should be further explored in myeloma, as peripheral blood biomarkers of diagnosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10936243	Despite research demonstrating a link between appropriate clinical settings, good animal welfare and positive clinical outcomes in cats (e.g. good environmental management can reduce the likelihood of abnormal behaviour development [Amat et al. 2008; Palestrini 2009; Rodan 2010; Stella et al. 2015], we know from person...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11055510	Wound healing experiments analyzed the effect of miR-135a-3p interaction with IL1RAP on the migration rate of SKOV3 cells. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O" ], "tokens": [ "Wound", "healing", "experiment...
PMC9621239	Apart from the 16 aa sites with higher Sn in the tumour tissues, there were 22 and 23 significant aa sites located within the transactivation domain and the strongly conserved region, respectively, of which four aa sites overlapped among these three mutation types (Figure 2K), including x111, x119, x123 and x134 (Figur...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11703992	Additionally, aspartate aminotransferase and C-reactive protein were identified as causal biomarkers in GCA (Fig. S6B, C).Fig.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "aspartate", ...
PMC11640419	A statistical significance level of p < 0.05 was employed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "statistical", "significance", "level", "of", "p", "<", "0.05", "was", "employed", "."...
PMC10788478	Abbreviation: LGR6, leucine‐rich repeat‐containing G protein‐coupled receptor 6.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Abbreviation", ":", "LGR6", ",", "leucine‐rich", "repeat‐containing", "G", "protein‐coupled", "recepto...
PMC9817179	The red circles represent the boundary within which the integrated fluorescence is considered ‘in puncta’.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "red", "circles", "represent", "the", ...
PMC10522430	Current treatment modalities for cervical cancer span surgery, chemotherapy, and radiotherapy , yet their efficacy is hampered by considerable side effects and susceptibility to relapse .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11732523	Good's syndrome (GS), first described by Robert Good in 1954, is characterized by the coexistence of thymoma and immunodeficiency .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11680391	A reduction in the number of dairy farms and increasing herd sizes have become global trends over recent decades , thus impacting the sector’s development.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11291490	b duCD40 gene expression levels in duPBMCs were measured by qRT-PCR.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "b", "duCD40", "gene", "expression", "levels", "in", "duPBMCs", "were", "measured", "b...
PMC10840195	The apoptosis of oe-Twist cells was inhibited compared to oe-NC in A498 cells (Fig. 4E).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "apoptosis", "of", "oe-Twist", "ce...
PMC11745600	Kuma and NOD.Cg-PrkdIl2rgWjl/SzJ (NRG)-Akita mice have been reported as mouse models exhibiting severe immune deficiency and spontaneous severe diabetes development.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Kuma", "and", "NOD.Cg-PrkdIl...
PMC11670407	Qualified RNA samples are required to have an A260/A280 ratio within the range of 1.8 to 2.0.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Qualified", "RNA", "samples", "are", "required", ...
PMC9429973	8 patients received rituximab maintenance after B-R (44%), and 48 patients following R-CHOP (64,95%).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "8", "patients", "...
PMC9429973	Importantly, combination of BIBF1120 and CHZ868 showed a synergistic effect (-45%, at IC50).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Importantly", ",", "combination", "of", ...
PMC11755624	Psoriasis is a disease with a complex pathophysiology involving interactions between immune cells and keratinocytes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Psoriasis", "is", "a", "disease", "with", "a", "complex", ...
PMC11577421	It is conceivable that the wild-type and mutant CHO cells could exhibit distinct endocytic phenotypes unrelated to surface GAGs, potentially influencing the results outlined in Figure 6B and complicating interpretation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11216402	To calculate the correlation for each group (i.e., Mes-like, Epi-like, TCGA-STAD), their mean gkm-SVM weight vectors were used for each group of samples.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10745221	Proteins with SDMA with molecular weights of approximately 15 kDa, 20 kDa, and 30 kDa were observed at a high level in the 143B, HCT116, and HeLa cells, while multiple proteins with ADMA were observed in these three cell lines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", ...
PMC11758416	Gate CFSE+ cells to analyze L cells and gate Annexin V+ cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Gate", "CFSE+", "cells", "to", "analyze", "L", "cells", "and", "gate", "An...
PMC7215722	Electrical resistance was expressed as Ω × cm2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Electrical", "resistance", "was", "expressed", "as", "Ω", "×", "cm2", "." ] } ]
PMC10213199	The results showed that all the key genes were in the first largest subnetwork.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "results", "showed", "that", "all", "the", "key", "genes",...
PMC11025866	VPM regulates many fewer genes than VPA, though both VPA and VPM have anti-convulsant and anti-viral properties.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "VPM", "regulates", "many", "fewer", "g...
PMC11750165	To test this hypothesis, we investigated whether PEX1 and Jagged2 associate in vitro by performing a co-immunoprecipitation assay with various constructs of zebrafish Jagged2 (Fig. 1A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11349530	VEGF suppresses immune responses by binding to its receptors (VEGFR1 and VEGFR2) on immune cells, activating the PI3K/Akt and MAPK pathways and contributing to CD8+ T cell exhaustion via expression of negative immune checkpoints, such as PD-1, CTLA-4, TIM-3 and others (79).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10470467	Low expression of RIPK1 is linked to a bad prognosis in head and neck squamous cell carcinoma and liver cancer (28, 29), whereas high expression of RIPK1 is linked to a poor prognosis in breast cancer (BC) and glioblastoma (30, 31).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11763126	In this study, peptidomics technology was employed to investigate the differentially expressed endogenous peptides in ccRCC.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "this", "study", ",", "peptidomics", "...
PMC11756907	The results for the ANOVA test were: p < 0.0001, n=3.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "results", "for", "the", "ANOVA", "test", "were", ":", "p", ...
PMC11066331	This finding suggests that the classification model is not influenced by a small number of dominant peaks and rather it is the cumulative effect of high number of variables with rather low weight that determines the robustness and accuracy of the model.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11721096	One non-ligand of TYR, dihydrotanshinone I, and two ligands (α-arbutin and quercitrin) were mixed to prepare a standard mixture designated as mS0.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11694066	E and F, Western blots of pCHK1, CHK1, pRPA2, RPA2, γH2AX, H2AX, and cleaved-PARP1 (cPARP) in JN1 (E) or R (F) cells exposed to DMSO control, PARPi talazoparib or olaparib, ATRi M4344 or AZD6738, or a combination of both for 48 hours.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8540692	Around 5-fold increase in the expression of RUNX3 was observed in A-172 and ~3.3 fold in U-138 MG cell line.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "O", "O", "O" ], "tokens": [ "Around", ...
PMC11509224	They were found to exert inhibitory activity against superoxide anion generation in fMLF/CB-stimulated human neutrophils, with IC50 values of 16.5, 13.1, and 17.4 µM, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10198699	In 2021, the descendants of Henrietta Lacks sued a well-known biotechnology company for the profits it made from the HeLa cell line.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O" ], "tokens": [ ...
PMC11496491	The bubble chart analysis of most significant in terms of biological processes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "bubble", "chart", "analysis", "of", "most", "significant", "in", "terms",...
PMC8623816	To extract the dsRNA of mycovirus, the mycelia of strain D122 were cultured on a cellophane membrane overlaying a PDA plate for 6 days.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10818573	The CT value was inversely proportional to the gene copy number, and the R value of the curve was 0.99.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "CT", "valu...
PMC10976516	One way to achieve more efficient systemic oncolytic virus delivery is through better protection against neutralization by several components of the host immune system.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC10936243	Some cats are fully indoor cats.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Some", "cats", "are", "fully", "indoor", "cats", "." ] } ]
PMC11515150	We labeled Jurkat cells with diluted CD5-Trunc-Fc protein and calculated the EC50 of 5D and 12 C as 15.49nM and 26.02nM, respectively (Fig. 1d).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11612508	The experiments were conducted three times for consistency.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "experiments", "were", "conducted", "three", "times", "for", "consistency", "." ] } ]
PMC5810978	All of these sterilized HuNoV-, HuSaV-, or BoNoV-positive fecal suspensions were aliquoted to individual tubes, stored at -70°C and thawed only once for cell culture trials.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9847912	Proteolytic cleavage at CA/SP1 requires the open, random-coil configuration of the peptide; in the 6HB form, the cleavage site is internalized within the bundle and is inaccessible to HIV-1 protease .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11774251	Further, Tan-I reduced the mRNA expression of several chemokines and antimicrobial peptides, such as CXCL2, CXCL5, CXCL8, CCL3, S100A7, and IL-1β, which is induced by TNF-α (Figure 3G–L).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11549062	Live‐cell imaging was employed to observe endocytic motility, while cell apoptosis was evaluated through Propidium Iodide staining.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Live‐cell", "imaging", "was", "employed", ...
PMC6160470	P-gp is a transmembrane protein and thus its activity highly depends on biochemical and biophysical properties of the membrane.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "P-gp", "is", "a", "transmembrane"...
PMC11659921	All the analysis methods and R package were implemented by R version 4.0.3.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "the", "analysis", "methods", "and", "R", "package", "were", "i...
PMC11730000	To investigate this, a fluorescent dye-based detection method was employed to detect superoxide in CHO-K1 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "To", "investigate", "this", ",", "a", ...
PMC11413393	Mice were randomized to either Dox supplemented water (1 mg/mL dox in water) or normal water upon tumor establishment (100–200 mm).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9681981	Contact of C. perfringens with Caco-2 cell culture To investigate the effect of contact duration on the gene expression of the studied toxins, sampling was performed at 0, 2, and 5 h post-contact.	[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11536589	Previous attempts to target KRAS were unsuccessful until the recent development of KRAS inhibitors like Adagrasib (MRTX849) and Sotorasib (AMG510).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11209164	Further details can be found in our published protocol .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Further", "details", "can", "be", "found", "in", "our", "published", "protocol", "." ] } ]
PMC10507284	Figure 3F displays the HRs a of these 10 TROAP‐derived genes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Figure", "3F", "displays", "the", "HRs", "a", "of", "these", "10", "TROAP‐derived", ...
PMC11740207	In lung cancer, research has indicated that EMT and MET contribute not only to its advancement but also to its development of resistance to therapies (Ren et al., 2013; Pastushenko and Blanpain, 2019).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11721587	The cells were thoroughly resuspended in lysis buffer [20 mM Hepes (pH 7.9), 1 mM MgCl2, 10 mM KCl, 1 mM DTT, 0.1 mM EDTA, and 1× Complete protease inhibitor cocktail] and incubated on ice for 10 min.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11682172	Inserts with pore sizes of 3.0 μm were used.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Inserts", "with", "pore", "sizes", "of", "3.0", "μm", "were", "used", "." ] } ]
PMC9429973	Part B consists of expansion cohorts of specific tumour indications, including pts with lymphoma.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Part", "B", "consists", "of", "expansion", "cohorts", "of",...
PMC11674441	Tumour specimens were collected immediately prior to neoantigen prediction and dendritic cell vaccine therapy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Tumour", "specimens", "were", "collected", "immediately", "prior", "to...
PMC9429973	The median follow-up was over 8 years.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "median", "follow-up", "was", "over", "8", "years", "." ] } ]
PMC11476106	However, culture media of both ES cell lines grown in 3D showed positive VN detection.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "culture", "media", "of", "both", ...
PMC11674146	Firstly, the number of patient samples used in this study was relatively small, and will be expanded in the future to include more lymphoma patients and a wider population, which will in turn strengthen the reliability of the findings.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9792775	The data were analyzed with GraphPad Prism software version 6.00 for Windows (La Jolla, CA, United States).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "data", "we...
PMC11700523	Kidney tissues were removed during euthanization.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Kidney", "tissues", "were", "removed", "during", "euthanization", "." ] } ]
PMC11049548	This behavior results from dissimilarities in the levels of several metabolites attributable to the differential modulation of underlying biochemical pathways.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "behavior", "results"...
PMC8984067	With the surface modification of UCNPs by Ce6 and anti-EpCAM, the positive charge on the surface of the entire nanoparticle is further reduced.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11701801	This data indicates that SMARCA4/SMARCA2-deficient and SS18–SSX fusion cell lines are highly sensitive to CP-C27.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "data", "indicates", "that", "SMARCA4/SMARCA2-deficient", ...
PMC11697703	We found downregulation of both miRs upon Fezf2 shRNA transfection (Figure 1D; miR-193b 0.58-fold downregulation; miR-365 0.46-fold upregulation) Together, these results indicate that the miR-193b∼365 cluster is enriched in corticospinal vs. callosal projection neurons and that its expression is positively regulated by...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11190238	In an EMT model of breast cancer cells, reduced binding of the cohesin complex component RAD21 at the loci of TGFB1 and ITGA5 leads to a loss of intrachromosomal interactions that allows recruitment of transcriptional machinery to the promoters of the mesenchymal genes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11796104	Additionally, clinical validation experiments were performed on selected circrna and miRNAs, and a portion of the results obtained is consistent with the preliminary predictions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11679326	Interestingly, altered N-glycosylation patterns affect the glycocalyx thickness of cells, through which mechanosensing may be regulated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Interestingly", ",", "altered", "N-glycosyla...
PMC10452486	Notably, the HLA-I sequence AYDGKDY is shared by classical (HLA-A, HLA-B, and HLA-C) and non-classical (HLA-E, HLA-F, and HLA-G) HLA-I and by Face-2 involved in homo and heterodimerization, although it is lacking in the HCs of HLA-II.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9895440	Sorted single cells were then loaded onto a 10x Genomics Chromium NEXT GEM chip G. Libraires were prepared following the 10x Genomics protocol for 3′ gene expression profiling (CG000315, Rev C) and cDNA or library quality was assessed using a 4200 TapeStation System (Agilent).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9545714	A value of 1 represents a twofold up‐ or downregulation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "value", "of", "1", "represents", "a", "twofold", "up‐", "or", "downregulation", "." ...
PMC9429973	The long-term effect of high Ferritin levels is not fully documented, but it has the potential to promote significant organ dysfunction.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "long-...
PMC11632064	Non-mitochondrial respiration was defined as respiration in cells treated with rotenone and antimycin A, and was subtracted from all OCR values.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Non-mitochondrial"...
PMC9429973	The outcome was reviewed for title and abstract independently by the two first authors.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "outcome", "was", "reviewed", "for", "title", "and", "abst...
PMC11544122	Our results are consistent with the hypothesis that SNX9 acts as a cargo adaptor and recruits pCXCR4 for CME.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Our", "results", "are", "consiste...
PMC8389560	At the same time, no connection was shown for the anticancer action of SeNP through the regulation of Ca homeostasis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "At", "the", "same...
PMC10529414	The mammalian genome contains 3 TF-encoding RUNX genes that are involved in different differentiation processes and developmental stages.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "mammalian", "genome", "contains", ...

PMC9352806

Bitter melon (Momordica charantia L.) is recognized as a medicinal and edible plant for obesity and diabetes prevention due to its numerous active ingredients, like polysaccharides, saponins, peptides or flavonoids (Bai et al., 2018).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC7612475

RNAseH1 induction in these cells did not alter sensitivity to olaparib or etoposide, indicating that the induction of DNA damage, and subsequent DNA repair and cellular survival following treatment with these agents, is not dependent on R-loops (Supplementary Fig. S4D).

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PMC7762347

The cDNA High Capacity Archive Kit, Taqman Gene Expression Assays, and Taqman Universal PCR Master Mix were purchased from Applied Biosystems (Waltham, MA, USA).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9250505

No significant differences were observed in the percentage of BAD-positive cells between the different treatment groups.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "No", "significant", "differences", "were", "observed", ...

PMC11052306

Four dendrons (7a-G1, 7b-G1, 8a-G1, and 8b-G1) were active against the HCT116 cell line at a concentration of 10 M but not at 10 M. These four dendrons were then tested with the non-cancerous RPE1 cells and were deceptively found to be even more toxic, as shown in Figure 10.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11543853

Inhibiting post-endocytic membrane remodeling with wiskostatin promoted abortive enterovirus genome release in endosomes.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Inhibiting", "post-endocytic", "membrane", "remodeling", "with", "wiskostatin", "...

PMC11747949

PD‐L1 expression decreased in hypoxia and in transwell assay (Figure 1D,E).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "PD‐L1", "expression", "decreased", "in", "hypoxia", "and", ...

PMC9429973

Median follow-up was 61.5 months (IQR 49.7 – 72.9 months).

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PMC11755519

These results indicate that activation of Akt and ERK pathways may be involved in the exosome-stimulated proliferation of bladder cancer cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "results", ...

PMC8633974

Targeted HIV-1 gene therapy requires specific recognition of diverse proviral sequences.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Targeted", "HIV-1", "gene", "therapy", "requires", "specific", "recognition", "of", "divers...

PMC8469018

Hoestch 33342 (Thermo Fisher Scientific, Waltham, MA, USA) and MitoTracker Green FM (Thermo Fisher Scientific, Waltham, USA) were used to control fractionation quality.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11237030

AQP5 expression stability over-time.

[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "AQP5", "expression", "stability", "over-time", "." ] } ]

PMC11682172

Data representative of three independent experiments.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "representative", "of", "three", "independent", "experiments", "." ] } ]

PMC11714165

On the other hand, activated osteoclasts secrete calcium ions, insulin like growth factors (IGFs) and transforming growth factor‐β (TGF‐β), which promote osteosarcoma cell proliferation and invasion.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11739484

P-value < 0.05.

[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "P-value", "<", "0.05", "." ] } ]

PMC11391695

However, si-ACYP2 + si-TERT treatment restored these properties in SMMC-7721 and BEL-7404 cells (Fig. 4F, Fig. S5B, D).

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PMC7802142

After incubation with HRP-conjugated secondary antibodies, the signals were visualized using ECL Substrates (Bio-Rad).

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PMC11774251

Topical applications were administered daily for 6 days, with the experiment ending on day 7.

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PMC11686380

First, unstable variant GAP43 can be still functional, and may have a protective effect to ameliorate morphological abnormalities.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "First", ",", "unstable", ...

PMC9429973

Our findings show that PDIA3, BTN1A1, APRIL and complement proteins should be further explored in myeloma, as peripheral blood biomarkers of diagnosis.

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PMC10936243

Despite research demonstrating a link between appropriate clinical settings, good animal welfare and positive clinical outcomes in cats (e.g. good environmental management can reduce the likelihood of abnormal behaviour development [Amat et al. 2008; Palestrini 2009; Rodan 2010; Stella et al. 2015], we know from person...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11055510

Wound healing experiments analyzed the effect of miR-135a-3p interaction with IL1RAP on the migration rate of SKOV3 cells. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O" ], "tokens": [ "Wound", "healing", "experiment...

PMC9621239

Apart from the 16 aa sites with higher Sn in the tumour tissues, there were 22 and 23 significant aa sites located within the transactivation domain and the strongly conserved region, respectively, of which four aa sites overlapped among these three mutation types (Figure 2K), including x111, x119, x123 and x134 (Figur...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11703992

Additionally, aspartate aminotransferase and C-reactive protein were identified as causal biomarkers in GCA (Fig. S6B, C).Fig.

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PMC11640419

A statistical significance level of p < 0.05 was employed.

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PMC10788478

Abbreviation: LGR6, leucine‐rich repeat‐containing G protein‐coupled receptor 6.

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PMC9817179

The red circles represent the boundary within which the integrated fluorescence is considered ‘in puncta’.

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PMC10522430

Current treatment modalities for cervical cancer span surgery, chemotherapy, and radiotherapy , yet their efficacy is hampered by considerable side effects and susceptibility to relapse .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11732523

Good's syndrome (GS), first described by Robert Good in 1954, is characterized by the coexistence of thymoma and immunodeficiency .

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PMC11680391

A reduction in the number of dairy farms and increasing herd sizes have become global trends over recent decades , thus impacting the sector’s development.

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PMC11291490

b duCD40 gene expression levels in duPBMCs were measured by qRT-PCR.

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PMC10840195

The apoptosis of oe-Twist cells was inhibited compared to oe-NC in A498 cells (Fig. 4E).

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PMC11745600

Kuma and NOD.Cg-PrkdIl2rgWjl/SzJ (NRG)-Akita mice have been reported as mouse models exhibiting severe immune deficiency and spontaneous severe diabetes development.

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PMC11670407

Qualified RNA samples are required to have an A260/A280 ratio within the range of 1.8 to 2.0.

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PMC9429973

8 patients received rituximab maintenance after B-R (44%), and 48 patients following R-CHOP (64,95%).

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PMC9429973

Importantly, combination of BIBF1120 and CHZ868 showed a synergistic effect (-45%, at IC50).

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PMC11755624

Psoriasis is a disease with a complex pathophysiology involving interactions between immune cells and keratinocytes.

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PMC11577421

It is conceivable that the wild-type and mutant CHO cells could exhibit distinct endocytic phenotypes unrelated to surface GAGs, potentially influencing the results outlined in Figure 6B and complicating interpretation.

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PMC11216402

To calculate the correlation for each group (i.e., Mes-like, Epi-like, TCGA-STAD), their mean gkm-SVM weight vectors were used for each group of samples.

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PMC10745221

Proteins with SDMA with molecular weights of approximately 15 kDa, 20 kDa, and 30 kDa were observed at a high level in the 143B, HCT116, and HeLa cells, while multiple proteins with ADMA were observed in these three cell lines.

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PMC11758416

Gate CFSE+ cells to analyze L cells and gate Annexin V+ cells.

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PMC7215722

Electrical resistance was expressed as Ω × cm2.

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PMC10213199

The results showed that all the key genes were in the first largest subnetwork.

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PMC11025866

VPM regulates many fewer genes than VPA, though both VPA and VPM have anti-convulsant and anti-viral properties.

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PMC11750165

To test this hypothesis, we investigated whether PEX1 and Jagged2 associate in vitro by performing a co-immunoprecipitation assay with various constructs of zebrafish Jagged2 (Fig. 1A).

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PMC11349530

VEGF suppresses immune responses by binding to its receptors (VEGFR1 and VEGFR2) on immune cells, activating the PI3K/Akt and MAPK pathways and contributing to CD8+ T cell exhaustion via expression of negative immune checkpoints, such as PD-1, CTLA-4, TIM-3 and others (79).

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PMC10470467

Low expression of RIPK1 is linked to a bad prognosis in head and neck squamous cell carcinoma and liver cancer (28, 29), whereas high expression of RIPK1 is linked to a poor prognosis in breast cancer (BC) and glioblastoma (30, 31).

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PMC11763126

In this study, peptidomics technology was employed to investigate the differentially expressed endogenous peptides in ccRCC.

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PMC11756907

The results for the ANOVA test were: p < 0.0001, n=3.

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PMC11066331

This finding suggests that the classification model is not influenced by a small number of dominant peaks and rather it is the cumulative effect of high number of variables with rather low weight that determines the robustness and accuracy of the model.

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PMC11721096

One non-ligand of TYR, dihydrotanshinone I, and two ligands (α-arbutin and quercitrin) were mixed to prepare a standard mixture designated as mS0.

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PMC11694066

E and F, Western blots of pCHK1, CHK1, pRPA2, RPA2, γH2AX, H2AX, and cleaved-PARP1 (cPARP) in JN1 (E) or R (F) cells exposed to DMSO control, PARPi talazoparib or olaparib, ATRi M4344 or AZD6738, or a combination of both for 48 hours.

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PMC8540692

Around 5-fold increase in the expression of RUNX3 was observed in A-172 and ~3.3 fold in U-138 MG cell line.

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PMC11509224

They were found to exert inhibitory activity against superoxide anion generation in fMLF/CB-stimulated human neutrophils, with IC50 values of 16.5, 13.1, and 17.4 µM, respectively.

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PMC10198699

In 2021, the descendants of Henrietta Lacks sued a well-known biotechnology company for the profits it made from the HeLa cell line.

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PMC11496491

The bubble chart analysis of most significant in terms of biological processes.

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PMC8623816

To extract the dsRNA of mycovirus, the mycelia of strain D122 were cultured on a cellophane membrane overlaying a PDA plate for 6 days.

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PMC10818573

The CT value was inversely proportional to the gene copy number, and the R value of the curve was 0.99.

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PMC10976516

One way to achieve more efficient systemic oncolytic virus delivery is through better protection against neutralization by several components of the host immune system.

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PMC10936243

Some cats are fully indoor cats.

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PMC11515150

We labeled Jurkat cells with diluted CD5-Trunc-Fc protein and calculated the EC50 of 5D and 12 C as 15.49nM and 26.02nM, respectively (Fig. 1d).

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PMC11612508

The experiments were conducted three times for consistency.

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PMC5810978

All of these sterilized HuNoV-, HuSaV-, or BoNoV-positive fecal suspensions were aliquoted to individual tubes, stored at -70°C and thawed only once for cell culture trials.

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PMC9847912

Proteolytic cleavage at CA/SP1 requires the open, random-coil configuration of the peptide; in the 6HB form, the cleavage site is internalized within the bundle and is inaccessible to HIV-1 protease .

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PMC11774251

Further, Tan-I reduced the mRNA expression of several chemokines and antimicrobial peptides, such as CXCL2, CXCL5, CXCL8, CCL3, S100A7, and IL-1β, which is induced by TNF-α (Figure 3G–L).

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PMC11549062

Live‐cell imaging was employed to observe endocytic motility, while cell apoptosis was evaluated through Propidium Iodide staining.

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PMC6160470

P-gp is a transmembrane protein and thus its activity highly depends on biochemical and biophysical properties of the membrane.

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PMC11659921

All the analysis methods and R package were implemented by R version 4.0.3.

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PMC11730000

To investigate this, a fluorescent dye-based detection method was employed to detect superoxide in CHO-K1 cells.

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PMC11413393

Mice were randomized to either Dox supplemented water (1 mg/mL dox in water) or normal water upon tumor establishment (100–200 mm).

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PMC9681981

Contact of C. perfringens with Caco-2 cell culture To investigate the effect of contact duration on the gene expression of the studied toxins, sampling was performed at 0, 2, and 5 h post-contact.

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PMC11536589

Previous attempts to target KRAS were unsuccessful until the recent development of KRAS inhibitors like Adagrasib (MRTX849) and Sotorasib (AMG510).

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PMC11209164

Further details can be found in our published protocol .

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PMC10507284

Figure 3F displays the HRs a of these 10 TROAP‐derived genes.

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PMC11740207

In lung cancer, research has indicated that EMT and MET contribute not only to its advancement but also to its development of resistance to therapies (Ren et al., 2013; Pastushenko and Blanpain, 2019).

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PMC11721587

The cells were thoroughly resuspended in lysis buffer [20 mM Hepes (pH 7.9), 1 mM MgCl2, 10 mM KCl, 1 mM DTT, 0.1 mM EDTA, and 1× Complete protease inhibitor cocktail] and incubated on ice for 10 min.

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PMC11682172

Inserts with pore sizes of 3.0 μm were used.

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PMC9429973

Part B consists of expansion cohorts of specific tumour indications, including pts with lymphoma.

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PMC11674441

Tumour specimens were collected immediately prior to neoantigen prediction and dendritic cell vaccine therapy.

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PMC9429973

The median follow-up was over 8 years.

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PMC11476106

However, culture media of both ES cell lines grown in 3D showed positive VN detection.

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PMC11674146

Firstly, the number of patient samples used in this study was relatively small, and will be expanded in the future to include more lymphoma patients and a wider population, which will in turn strengthen the reliability of the findings.

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PMC9792775

The data were analyzed with GraphPad Prism software version 6.00 for Windows (La Jolla, CA, United States).

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PMC11700523

Kidney tissues were removed during euthanization.

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PMC11049548

This behavior results from dissimilarities in the levels of several metabolites attributable to the differential modulation of underlying biochemical pathways.

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PMC8984067

With the surface modification of UCNPs by Ce6 and anti-EpCAM, the positive charge on the surface of the entire nanoparticle is further reduced.

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PMC11701801

This data indicates that SMARCA4/SMARCA2-deficient and SS18–SSX fusion cell lines are highly sensitive to CP-C27.

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PMC11697703

We found downregulation of both miRs upon Fezf2 shRNA transfection (Figure 1D; miR-193b 0.58-fold downregulation; miR-365 0.46-fold upregulation) Together, these results indicate that the miR-193b∼365 cluster is enriched in corticospinal vs. callosal projection neurons and that its expression is positively regulated by...

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PMC11190238

In an EMT model of breast cancer cells, reduced binding of the cohesin complex component RAD21 at the loci of TGFB1 and ITGA5 leads to a loss of intrachromosomal interactions that allows recruitment of transcriptional machinery to the promoters of the mesenchymal genes.

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PMC11796104

Additionally, clinical validation experiments were performed on selected circrna and miRNAs, and a portion of the results obtained is consistent with the preliminary predictions.

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PMC11679326

Interestingly, altered N-glycosylation patterns affect the glycocalyx thickness of cells, through which mechanosensing may be regulated.

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PMC10452486

Notably, the HLA-I sequence AYDGKDY is shared by classical (HLA-A, HLA-B, and HLA-C) and non-classical (HLA-E, HLA-F, and HLA-G) HLA-I and by Face-2 involved in homo and heterodimerization, although it is lacking in the HCs of HLA-II.

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PMC9895440

Sorted single cells were then loaded onto a 10x Genomics Chromium NEXT GEM chip G. Libraires were prepared following the 10x Genomics protocol for 3′ gene expression profiling (CG000315, Rev C) and cDNA or library quality was assessed using a 4200 TapeStation System (Agilent).

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PMC9545714

A value of 1 represents a twofold up‐ or downregulation.

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PMC9429973

The long-term effect of high Ferritin levels is not fully documented, but it has the potential to promote significant organ dysfunction.

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PMC11632064

Non-mitochondrial respiration was defined as respiration in cells treated with rotenone and antimycin A, and was subtracted from all OCR values.

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PMC9429973

The outcome was reviewed for title and abstract independently by the two first authors.

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PMC11544122

Our results are consistent with the hypothesis that SNX9 acts as a cargo adaptor and recruits pCXCR4 for CME.

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PMC8389560

At the same time, no connection was shown for the anticancer action of SeNP through the regulation of Ca homeostasis.

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PMC10529414

The mammalian genome contains 3 TF-encoding RUNX genes that are involved in different differentiation processes and developmental stages.

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