OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC11271278	We also observed the presence of ecDNA aggregates in some of the interphase nuclei, indicative of ecDNA hubs as previously reported in other cancer cell lines (Fig. S9B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11269933	Phosphorylation of PKM2 at the Thr454 site by PIM2 promotes glycolysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Phosphorylation", "of", "PKM2", "at", "the", "Thr454", "site", "by", "PIM2", "promote...
PMC11675244	Similarly, boosting β-catenin-CBP pharmacologically or genetically diminishes stem-like features and inhibits non-stem to stem cell conversion .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Similarly", ",", "boosting", "β-catenin-CBP", "ph...
PMC11585565	Amino acid sequence alignment of CNNM4 across various organisms. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Amino", "acid", "sequence", "alignment", "of", "CNNM4", "across", "various", "organisms", ".", ...
PMC5716223	From each sample, 15–20 μg of proteins have been utilized for immunoblotting with the following antibodies: myogenin (sc-576), Hsp27 (sc-1048), p75 (sc-56448) and TrkA (sc-20539) (1:1000, Santa-Cruz Biotechnology), β-actin (A1978) (1:3000, Sigma), anti-embryonic MyHC (F1652) (1:1000, Biovalley) and MyHC IIB (BFF3) (1:1...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7802142	Thus, DPCs are considered to be a key signaling center responsible for the induction and maintenance of follicular development, regulation of the hair cycle, as well as the regeneration of HFs .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11699465	CE, Cytoplasmic extraction; NFP, Nuclear free protein; DBP, DND binding protein. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CE", ",", "Cytoplasmic", "extraction", ";", ...
PMC11036064	Based on our study, hsa-miR-34a-5p ectopic expression enhances the chemosensitivity of A172 cells to temozolomide and increases the anti-tumoral effect of temozolomide on the cell viability, migration, cell cycle, apoptosis, and clonogenicity of A172 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11087766	to import each other’s proteins.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "to", "import", "each", "other", "’s", "proteins", "." ] } ]
PMC11732635	The prognosis for CAEBV varies.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "prognosis", "for", "CAEBV", "varies", "." ] } ]
PMC9429973	The KM curve analysis showed that the TM frailty score could well distinguish the risk of AEs between the Fit and Frail groups (P<0.05).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11704834	As shown in Fig. 1C, high TLE1 expression failed to correlate with LUSC patient survival rates.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "As", "shown", "in", "Fig.", "1C", ",", ...
PMC9917080	Selenium nanoparticles (SeNPs) in glioblastoma cells dose-dependently induced an increase in [Ca]i (Figure 1C) with EC50 = 2.5 ± 0.001 μg/mL (Figure 1G) and in astrocytes of the cerebral cortex (Figure 1D) with EC50 = 1.3 ± 0.004 μg /mL (Figure 1H).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8735881	Titers of pseudotyped virions were determined in TZM-bl cells by a TCID50 assay.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Titers", "of", "pseudotyped", "virions", "were", "determined", "in", "TZM-b...
PMC9429973	Methods: Key eligibility criteria and study design are outlined in the Figure.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Methods", ":", "Key", "eligibility", "criteria", "and", "study", "design", ...
PMC10538569	Blocking the egress of T cells from lymph nodes into efferent lymph vessels at the onset of HIV-1 infection limited HIV-1 dissemination and reduced plasma viremia (16, 43).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7039683	In them GFP expression is detectable in the enveloping layer starting at 5.25 hpf (50% epiboly) (Figure 4—figure supplement 1I’) and still visible at five dpf, although with lower intensity than in Tg(IRF6-9.7:gfp) transgenic animals at this stage (Figure 4F), consistent with lower expression levels of znf750 in compar...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11045125	Lentiviral vectors containing shRNA targeting Myb (RHS3979-201768911, RHS3979-201768912, RHS3979-201768914, RHS3979-201768915, RHS3979-201786168, RHS3979-201799542) and STAT3 (RHS3979-201751956, RHS3979-201751957, RHS3979-201751958, RHS3979-201751959, RHS3979-201751960) on a pLKO backbone were obtained from Horizon Dis...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8481254	To better investigate the biological function of CDK19 in the O-GlcNAcylation of liver cancer cells, we knocked out or overexpressed CDK19 and found a critical role for CDK19 in O-GlcNAcylation levels in liver cancer cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10253553	Maximal suppression of NDRG1 phosphorylation (Thr346) was correlated with a statistically significant increase in NDRG1 mRNA in response to 250 and 1000 nM Torin 2 treatments (Figure 3C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11411131	Both TrxR1-GFP and TrxR1-C-GFP exhibited a dose-dependent decrease in signal intensity upon MeHg exposure. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Both", "TrxR1-GFP", "and", "TrxR1-C-GFP", "exhibited", "a", ...
PMC11422497	RT-qPCR, reverse transcription- quantitative PCR.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "RT-qPCR", ",", "reverse", "transcription-", "quantitative", "PCR", "." ] } ]
PMC7802142	According to previous studies, minoxidil may cause high rate of adverse effects, such as burning or pruritus at the application site, allergic contact dermatitis and cardiovascular effects .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11721277	However, an increase in the RHT level to 3.61 ± 0.44% was observed when incubated at 95 °C for 15 min.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC3734024	Although FasLIL-10 B cells might be more frequent in animals mounting an active immune response, their extreme paucity in naïve mice has made characterizing these cells further technically difficult.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8922418	Anti-HIV-1 gene therapy by CRISPR/SaCas9 requires careful in vivo investigation in animal model settings.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Anti-HIV-1", "gene", "therapy", "by", "CRISPR/SaCas9", "requires", "ca...
PMC11243198	All assays were performed in triplicate.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "assays", "were", "performed", "in", "triplicate", "." ] } ]
PMC11264242	Our work has identified the proto-oncogene FYN as a direct target of SS18-SSX and shown that suppression of SS18-SSX by a potent HDAC inhibitor (FK228) increases FYN expression levels, which may in turn reduces the treatment response of synovial sarcoma cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8740518	A confidence interval of 95% was used.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "confidence", "interval", "of", "95", "%", "was", "used", "." ] } ]
PMC11739504	According to previous research, garcinol inhibits the acetyltransferase activity of Kat2b.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "According", "to", "previous", "research", ",", "garcinol", "inhibits", "the", "a...
PMC11675244	These genes are linked to cell proliferation, cell cycle progression, growth factor expression, apoptosis, angiogenesis, and the expansion of stem cell states, all of which are crucial traits in some cancer cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11670407	Quantitative data were presented as means ± S.D.s. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Quantitative", "data", "were", "presented", "as", "means", "±", "S.D.s", ".", "(" ] } ]
PMC11765988	Increased lymphoma risk has been described even in the one-year period after sarcoidosis diagnosis .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Increased", "lymphoma", "risk", "has", "been", "described", "even", ...
PMC9429973	Our results substantiate the interest of EV as liquid biopsies in myeloma and future validation in independent clinical settings is urged.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Our", "results", ...
PMC11283030	Original magnification 200×; bars, 50 μm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Original", "magnification", "200", "×", ";", "bars", ",", "50", "μm", "." ] } ]
PMC11391695	Following this, si-TERT and si-TERT + si-ACYP2 constructs were fabricated and their transfection efficiencies were validated (Fig. S5A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Following", "this", ...
PMC9429973	Indeed, a key finding from patient discussions showed that Hb levels and the need for transfusions is not comparable between different patients and even non-comparable over time meaning that the maximal benefit and timing of transfusions cannot be determined from Hb level alone.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11534035	Relative to this control, A431 cells treated with 1 μM of G1 showed a slight but insignificant reduction in the number of colonies formed.	[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ],...
PMC11650848	This mQTL resides within a DMR of the first intron on an alternative ZFP57 transcript.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "mQTL", "resides", "within", "a", "DMR", "of", ...
PMC5363531	SFKs are activated in MPM cell lines and tissue specimens when compared with normal mesothelial cells .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "SFKs", "are", "activated", "in", "MPM", "cell", ...
PMC8540692	Before the analysis, the fixed cells were washed with PBS buffer, stained, and subjected to 0.5 h incubation at room temperature in the darkness.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11656048	Shikonin induced mitochondria damage in OS cells. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Shikonin", "induced", "mitochondria", "damage", "in", "OS", "cells", ".", "(" ] } ]
PMC11367146	Cells were cultured in Dulbecco's Minimum Essential Medium (DMEM) with 10 % FBS, 1 % antibiotic-antimycotic solution and 1 % L-glutamine (200 mM).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9739791	At this wavelength, NCs 10 generate upconversion luminescence at around 670 nm , which then activate Phorbiplatin prodrug 9 on the surface of the nanocrystals and induce the release of initial Pt(II) complex oxaliplatin.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Image: Summary/Conclusion: Our data on first line DLBLC patients with unfavorable disease features treated with R-DA-EPOCH regimen do not confirm previously reported observations of improved response rates nor improved PFS with concomitant statin use.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11802855	The CXCL7 overexpression and control lentiviruses were obtained from Genechem Biotechnology Co., Ltd. (Shanghai, China).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "CXCL7", "overexpression", ...
PMC11754436	The results demonstrated that the expression levels of miR-362-5p in OS cells were significantly upregulated (Fig. 5A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "results", ...
PMC6684588	Data are means ± SEM (n = 11). **	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "are", "means", "±", "SEM", "(", "n", "=", "11", ")", ".", ...
PMC11547917	The TAC of the extracts was evaluated at 4.82 ± 0.03 mg/mL. A higher absorbance value indicates a higher level of antioxidant activity .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...
PMC10907726	Then the cells were treated with DATS for 24 and 48 h. After that, add 10 μl of cell counting kit8 (CCK8) (#CK04, Dojindo, Japan) reagent to each well and incubated at cell incubator for 2 h. Measure the absorbance at 450 nm of each hole using a microplate reader (BioTek, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11344246	The top ranked proteins are given in Table 1, with the full list available in Supplementary Table S3.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "top", "ranked", "proteins"...
PMC11796104	It is believed to encode an oncogenic protein and has been reported in various types of cancer .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "is", "believed", "to", "encode", "an"...
PMC9429973	This analysis shows a representative population of the patients in real clinical practice in Spain and analyzes the similarities and differences in the efficacy and safety of the treatments under study (with and without monoclonal antibody), for the first months.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11787381	The present work firstly confirmed the capacity of bambuterol to display in cellulo neuroprotective activities, reduction of Tau hyperphosphorylation and preservation of synapses in rat hippocampal neuronal cultures intoxicated with Aβ peptides.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9220170	In addition, its relationship with GP78 (AMFR) and RMA1 (RNF5) proteins, which are actively involved in polyubiquitinylation and proteasomal degradation of proteins, has been shown .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11419566	Additionally, PA is an effective antitumor agent.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "PA", "is", "an", "effective", "antitumor", "agent", "." ] } ]
PMC11612315	Blood glucose levels were measured via an Accu-Chek Performa glucometer (Roche, Mannheim, Germany).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Blood", "glucose", "levels", "were", "measured", ...
PMC11721587	In the following, we refer to this SDS-resistant Fu dimer as “mature” form and the process of its formation as “Fu maturation” to distinguish from the process of Fu kinase activation. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9878278	Data is presented as mean ± SEM from at least 3–5 independent experiments. *	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "is", "presented", "as", "mean", "±", "SEM", "from", ...
PMC11721064	Vimentin expression showed the highest level at P0-P3 SKCs and was very faint from P1 SKCs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Vimentin", "expression", "showed", "the", "highest", "...
PMC11676674	CHO-K1 cells were seeded at a density of 2000 cells/well in 96-well culture plates and allowed to stabilize at 37 °C in a 5% CO2 atmosphere for 24 h. Then, the cells were exposed to C. monspeliensis extract concentrations in the range of 1–600 μg/mL (2-fold increase) for 24 h. We could not increase the concentration mo...	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7090062	Our findings provide compelling evidence for the mechanism underlying autophagy initiation in IM-resistant GIST cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Our", "findings", "provide", "compelling", "evidence", "for", ...
PMC11359735	Unfed mosquitoes were removed after feeding and mosquitoes were maintained as outlined above, except that the incubator temperature was 25 C. Human erythrocytes used to set up the cultures are collected weekly from healthy donors under an institutional review board–approved protocol.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Response to vaccination was not affected by the spleen status (anatomic and functional asplenia vs spleen presence) or the immunoglobulins’ serum levels.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC8632470	Dugan had pretreated HEK293 cells with 10–100 μM concentrations of quercetin.	[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Dugan", "had", "pretreated", "HEK293", "cells", "with", "10–100", "μM", "concentra...
PMC6379402	p-val)Cell viability change (p-val) TOPAZ1 PMID:234786284.04E-02 HLA-DQA2 PMID: 275398871.21E-01 HLA-DQA2 PMID:275398872.57E-02 ECT2L intOgen2.52E-029.52E-02 ECT2L intOgen2.44E-021.91E-01 PNMA6A 2.32E-024.04E-02 VCP PMID: 187987391.13E-024.04E-02 MAGEB16 PMID: 114547054.04E-02 ARID3A PMID: 224697801.38E-014.04E-02 ERIC...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Results: At the moment of detected Covid19 infection, 37pts (70%) had active MM, and 16pts (30%) were in the state of follow-up during remission of disease.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10530622	Despite numerous efforts to comprehend the mechanisms governing oxalate absorption and excretion processes, there remain gaps that need to be addressed (for review, see ).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Median age at diagnosis was 66 years and it did not differ in both groups.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Median", "age", "at", "diagnosis", "was", "66", "years", ...
PMC10890307	Cells were incubated for 20 min at 37 °C, washed using BD wash buffer, and total DNA was stained with 7-amino-actinomycin D (7-AAD), followed by flow cytometric analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8358176	In the final step, Ficoll density gradient centrifugation (Sigma, Germany) was employed for the isolation of the peripheral mononuclear cells (PBMCs) isolated and for the extraction of total RNA.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11585994	In this study, we employed generation 5 PAMAM (G5-PAMAM, henceforth referred to as G5) to encapsulate both sgc8 and siBCL11B, resulting in the formation of G5-sgc8-siBCL11B nanoparticles for targeted therapy of T-ALL.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC2010673	Monoclonal antibody against an osteogenic-sarcoma cell line (791T) was prepared by production and cloning of a somatic-cell hybrid between the mouse myeloma P3-NS1 and spleen cells from 791T-immunized mice.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC11727000	We chose to validate the data through experiments involving BRCA2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "chose", "to", "validate", "the", "data", "through", "experiments", "involving", "BRCA2", ...
PMC11001582	Graph, mean ± s.e.m.,	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Graph", ",", "mean", "±", "s.e.m", ".", "," ] } ]
PMC9776316	In both A2780cisR and SKOV3cisR cell lines, treatment of cisplatin led to a significant increase of XRCC4 promoter activity; by contrast, mutation of cJUN binding site to XRCC4 promoter diminished the effect of cisplatin in the upregulating of XRCC4 promoter activity.	[ { "tags": [ "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC9776316	Platinum-based chemotherapy regimen has been the most actively used as a first-line treatment of ovarian cancer for decades .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Platinum-based", "chemotherapy", "regimen", ...
PMC9429973	The proportions of pts with ≥1 SAE and ≥1 AESI were 49.4% (228/462) and 28.8% (133/462), respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC8494202	Therefore, our study findings support that CKAP2L is associated with poor prognosis of glioma, can be used as an independent risk factor, and has diagnostic value.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10772747	Our research findings in the apoptosis assay demonstrated that EBE compounds exhibited strong potential in inducing apoptosis in breast cancer cells, with a total of 93.6% of cells undergoing apoptosis and 5.5% undergoing necrosis (Figure 5).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11300639	Ns, not significant.	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "Ns", ",", "not", "significant", "." ] } ]
PMC11400680	Lastly, for the mAP50–95 scores (Figure 7F), the easy set was the highest, with a median (Q2) value of 0.46 (0.42±0.2), followed by the medium test set with a median (Q2) value of 0.25 (0.35±0.3), and the difficult test set with a median (Q2) value of 0.1 (0.19±0.2).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11342785	Across synMAP IDR-CORE chimeras, bundling efficiency (EC50) scaled with droplet formation activity in vitro (DDX4>FUS>LAF).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Across", "sy...
PMC11474209	Cu/Au/Pt TNs-encapsulated DNA hydrogel colorimetric biosensorTap water3.0 ng LFor colorimetric MC-LR detection, Cu/Au/Pt TNs-encapsulated DNA hydrogel was created.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cu/Au/Pt", "TNs-encapsulated", "DNA", ...
PMC11116779	After 24, 48, 72, and 96 h, the plates were read with a SynergyH1 BioTek spectrophotometer (Agilent, Santa Clara, United States) at 490 nm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11033180	Data are mean ± SEM, n = 8 cultures from 2 independent experiments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "are", "mean", "±", "SEM", ",", "n", "=", "8", ...
PMC6461034	For the latter cell line, driven by the serine/threonine kinase BRAF (not detected by pTyr‐based phosphoproteomics), downstream driver targets in the MEK‐ERK pathway (MAP2K1, MAP2K2, MAPK1, MAPK3) are highlighted (Fig 2B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5034105	In addition to the few cell lines previously reported, our study has identified a broad range of cell lines that are suitable for growing ZIKV as an alternative diagnostic tool in clinical virology laboratories.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11615743	As a chiral molecule of D‐DNA, L‐DNA exhibits high stability in serum and does not hybridize with complementary D‐DNA sequences in the environment, making it an ideal candidate for diagnostic and therapeutic applications.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The majority of patients were treated by phlebotomy with 1 or 2 units per month, before starting hydroxy urea.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "majority", "of", ...
PMC11604768	This study introduces an MPRA library designed to simultaneously screen thousands of candidate synthetic promoters in mammalian cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "study", "introduces", "an", "M...
PMC11269933	The phosphorylation at this site enhanced substrate binding and increases PK enzyme activity, thereby promoting ATP production to aid in heat-induced damage repair.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11335267	Coexpression of Alx3 with either POMC- or AgRP-neurons was assessed using coronal sections (20 μm) spanning the entire arcuate nucleus (bregma − 1.1 to -2.6 mm), after incubation with the Alx3 antibody and secondary Alexa Fluor-555 or Alexa Fluor-488 rabbit antibodies (Invitrogen).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10926885	Prostate cancer development has also been shown to be regulated by axonemal dynein heavy chain 8.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Prostate", "cancer", "development", "has", "also", "be...
PMC11774112	After 72 h, 85.6% of the DTIC was released from the DTIC-loaded micelles.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "72", "h", ",", "85.6", "%", "of", "the", ...
PMC11609529	H292 cells, which express a different fusion protein, CRTC1-MAML2, were used as a control.	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "H292", "cells", ",", "which", "express",...
PMC10033453	Assessment of VMG efficacy in syngeneic model of sarcoma WEHI 164 (A) Individual murine tumor volumes after treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Assessment", "of...
PMC10852540	The primers used to investigate the changes in the expression of these genes are given below in 5’-3’ order.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "primers", "used", ...
PMC10823017	mRNA levels of PKC-ι, PKC-ζ, and c-Myc for the siRNA (PKC-ι and PKC-ζ) treated (A) 786-0 and (B) Caki-1 cells against respective control samples based on quantitative real-time PCR (qPCR).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "O"...
PMC11615101	The antibody (α-Taxilin) was immobilized (3h, RT) on agarose beads,28 washed, and eluted in native elution buffer (provided).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...

PMC11271278

We also observed the presence of ecDNA aggregates in some of the interphase nuclei, indicative of ecDNA hubs as previously reported in other cancer cell lines (Fig. S9B).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11269933

Phosphorylation of PKM2 at the Thr454 site by PIM2 promotes glycolysis.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Phosphorylation", "of", "PKM2", "at", "the", "Thr454", "site", "by", "PIM2", "promote...

PMC11675244

Similarly, boosting β-catenin-CBP pharmacologically or genetically diminishes stem-like features and inhibits non-stem to stem cell conversion .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Similarly", ",", "boosting", "β-catenin-CBP", "ph...

PMC11585565

Amino acid sequence alignment of CNNM4 across various organisms. (

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PMC5716223

From each sample, 15–20 μg of proteins have been utilized for immunoblotting with the following antibodies: myogenin (sc-576), Hsp27 (sc-1048), p75 (sc-56448) and TrkA (sc-20539) (1:1000, Santa-Cruz Biotechnology), β-actin (A1978) (1:3000, Sigma), anti-embryonic MyHC (F1652) (1:1000, Biovalley) and MyHC IIB (BFF3) (1:1...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC7802142

Thus, DPCs are considered to be a key signaling center responsible for the induction and maintenance of follicular development, regulation of the hair cycle, as well as the regeneration of HFs .

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PMC11699465

CE, Cytoplasmic extraction; NFP, Nuclear free protein; DBP, DND binding protein. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CE", ",", "Cytoplasmic", "extraction", ";", ...

PMC11036064

Based on our study, hsa-miR-34a-5p ectopic expression enhances the chemosensitivity of A172 cells to temozolomide and increases the anti-tumoral effect of temozolomide on the cell viability, migration, cell cycle, apoptosis, and clonogenicity of A172 cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11087766

to import each other’s proteins.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "to", "import", "each", "other", "’s", "proteins", "." ] } ]

PMC11732635

The prognosis for CAEBV varies.

[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "prognosis", "for", "CAEBV", "varies", "." ] } ]

PMC9429973

The KM curve analysis showed that the TM frailty score could well distinguish the risk of AEs between the Fit and Frail groups (P<0.05).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...

PMC11704834

As shown in Fig. 1C, high TLE1 expression failed to correlate with LUSC patient survival rates.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "As", "shown", "in", "Fig.", "1C", ",", ...

PMC9917080

Selenium nanoparticles (SeNPs) in glioblastoma cells dose-dependently induced an increase in [Ca]i (Figure 1C) with EC50 = 2.5 ± 0.001 μg/mL (Figure 1G) and in astrocytes of the cerebral cortex (Figure 1D) with EC50 = 1.3 ± 0.004 μg /mL (Figure 1H).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8735881

Titers of pseudotyped virions were determined in TZM-bl cells by a TCID50 assay.

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PMC9429973

Methods: Key eligibility criteria and study design are outlined in the Figure.

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PMC10538569

Blocking the egress of T cells from lymph nodes into efferent lymph vessels at the onset of HIV-1 infection limited HIV-1 dissemination and reduced plasma viremia (16, 43).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC7039683

In them GFP expression is detectable in the enveloping layer starting at 5.25 hpf (50% epiboly) (Figure 4—figure supplement 1I’) and still visible at five dpf, although with lower intensity than in Tg(IRF6-9.7:gfp) transgenic animals at this stage (Figure 4F), consistent with lower expression levels of znf750 in compar...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11045125

Lentiviral vectors containing shRNA targeting Myb (RHS3979-201768911, RHS3979-201768912, RHS3979-201768914, RHS3979-201768915, RHS3979-201786168, RHS3979-201799542) and STAT3 (RHS3979-201751956, RHS3979-201751957, RHS3979-201751958, RHS3979-201751959, RHS3979-201751960) on a pLKO backbone were obtained from Horizon Dis...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8481254

To better investigate the biological function of CDK19 in the O-GlcNAcylation of liver cancer cells, we knocked out or overexpressed CDK19 and found a critical role for CDK19 in O-GlcNAcylation levels in liver cancer cells.

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PMC10253553

Maximal suppression of NDRG1 phosphorylation (Thr346) was correlated with a statistically significant increase in NDRG1 mRNA in response to 250 and 1000 nM Torin 2 treatments (Figure 3C).

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PMC11411131

Both TrxR1-GFP and TrxR1-C-GFP exhibited a dose-dependent decrease in signal intensity upon MeHg exposure. (

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PMC11422497

RT-qPCR, reverse transcription- quantitative PCR.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "RT-qPCR", ",", "reverse", "transcription-", "quantitative", "PCR", "." ] } ]

PMC7802142

According to previous studies, minoxidil may cause high rate of adverse effects, such as burning or pruritus at the application site, allergic contact dermatitis and cardiovascular effects .

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PMC11721277

However, an increase in the RHT level to 3.61 ± 0.44% was observed when incubated at 95 °C for 15 min.

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PMC3734024

Although FasLIL-10 B cells might be more frequent in animals mounting an active immune response, their extreme paucity in naïve mice has made characterizing these cells further technically difficult.

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PMC8922418

Anti-HIV-1 gene therapy by CRISPR/SaCas9 requires careful in vivo investigation in animal model settings.

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PMC11243198

All assays were performed in triplicate.

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PMC11264242

Our work has identified the proto-oncogene FYN as a direct target of SS18-SSX and shown that suppression of SS18-SSX by a potent HDAC inhibitor (FK228) increases FYN expression levels, which may in turn reduces the treatment response of synovial sarcoma cells.

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PMC8740518

A confidence interval of 95% was used.

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PMC11739504

According to previous research, garcinol inhibits the acetyltransferase activity of Kat2b.

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PMC11675244

These genes are linked to cell proliferation, cell cycle progression, growth factor expression, apoptosis, angiogenesis, and the expansion of stem cell states, all of which are crucial traits in some cancer cells.

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PMC11670407

Quantitative data were presented as means ± S.D.s. (

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PMC11765988

Increased lymphoma risk has been described even in the one-year period after sarcoidosis diagnosis .

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PMC9429973

Our results substantiate the interest of EV as liquid biopsies in myeloma and future validation in independent clinical settings is urged.

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PMC11283030

Original magnification 200×; bars, 50 μm.

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PMC11391695

Following this, si-TERT and si-TERT + si-ACYP2 constructs were fabricated and their transfection efficiencies were validated (Fig. S5A).

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PMC9429973

Indeed, a key finding from patient discussions showed that Hb levels and the need for transfusions is not comparable between different patients and even non-comparable over time meaning that the maximal benefit and timing of transfusions cannot be determined from Hb level alone.

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PMC11534035

Relative to this control, A431 cells treated with 1 μM of G1 showed a slight but insignificant reduction in the number of colonies formed.

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PMC11650848

This mQTL resides within a DMR of the first intron on an alternative ZFP57 transcript.

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PMC5363531

SFKs are activated in MPM cell lines and tissue specimens when compared with normal mesothelial cells .

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PMC8540692

Before the analysis, the fixed cells were washed with PBS buffer, stained, and subjected to 0.5 h incubation at room temperature in the darkness.

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PMC11656048

Shikonin induced mitochondria damage in OS cells. (

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PMC11367146

Cells were cultured in Dulbecco's Minimum Essential Medium (DMEM) with 10 % FBS, 1 % antibiotic-antimycotic solution and 1 % L-glutamine (200 mM).

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PMC9739791

At this wavelength, NCs 10 generate upconversion luminescence at around 670 nm , which then activate Phorbiplatin prodrug 9 on the surface of the nanocrystals and induce the release of initial Pt(II) complex oxaliplatin.

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PMC9429973

Image: Summary/Conclusion: Our data on first line DLBLC patients with unfavorable disease features treated with R-DA-EPOCH regimen do not confirm previously reported observations of improved response rates nor improved PFS with concomitant statin use.

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PMC11802855

The CXCL7 overexpression and control lentiviruses were obtained from Genechem Biotechnology Co., Ltd. (Shanghai, China).

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PMC11754436

The results demonstrated that the expression levels of miR-362-5p in OS cells were significantly upregulated (Fig. 5A).

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PMC6684588

Data are means ± SEM (n = 11). **

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PMC11547917

The TAC of the extracts was evaluated at 4.82 ± 0.03 mg/mL. A higher absorbance value indicates a higher level of antioxidant activity .

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PMC10907726

Then the cells were treated with DATS for 24 and 48 h. After that, add 10 μl of cell counting kit8 (CCK8) (#CK04, Dojindo, Japan) reagent to each well and incubated at cell incubator for 2 h. Measure the absorbance at 450 nm of each hole using a microplate reader (BioTek, USA).

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PMC11344246

The top ranked proteins are given in Table 1, with the full list available in Supplementary Table S3.

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PMC11796104

It is believed to encode an oncogenic protein and has been reported in various types of cancer .

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PMC9429973

This analysis shows a representative population of the patients in real clinical practice in Spain and analyzes the similarities and differences in the efficacy and safety of the treatments under study (with and without monoclonal antibody), for the first months.

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PMC11787381

The present work firstly confirmed the capacity of bambuterol to display in cellulo neuroprotective activities, reduction of Tau hyperphosphorylation and preservation of synapses in rat hippocampal neuronal cultures intoxicated with Aβ peptides.

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PMC9220170

In addition, its relationship with GP78 (AMFR) and RMA1 (RNF5) proteins, which are actively involved in polyubiquitinylation and proteasomal degradation of proteins, has been shown .

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PMC11419566

Additionally, PA is an effective antitumor agent.

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PMC11612315

Blood glucose levels were measured via an Accu-Chek Performa glucometer (Roche, Mannheim, Germany).

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PMC11721587

In the following, we refer to this SDS-resistant Fu dimer as “mature” form and the process of its formation as “Fu maturation” to distinguish from the process of Fu kinase activation. (

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PMC9878278

Data is presented as mean ± SEM from at least 3–5 independent experiments. *

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PMC11721064

Vimentin expression showed the highest level at P0-P3 SKCs and was very faint from P1 SKCs.

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PMC11676674

CHO-K1 cells were seeded at a density of 2000 cells/well in 96-well culture plates and allowed to stabilize at 37 °C in a 5% CO2 atmosphere for 24 h. Then, the cells were exposed to C. monspeliensis extract concentrations in the range of 1–600 μg/mL (2-fold increase) for 24 h. We could not increase the concentration mo...

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PMC7090062

Our findings provide compelling evidence for the mechanism underlying autophagy initiation in IM-resistant GIST cells.

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PMC11359735

Unfed mosquitoes were removed after feeding and mosquitoes were maintained as outlined above, except that the incubator temperature was 25 C. Human erythrocytes used to set up the cultures are collected weekly from healthy donors under an institutional review board–approved protocol.

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PMC9429973

Response to vaccination was not affected by the spleen status (anatomic and functional asplenia vs spleen presence) or the immunoglobulins’ serum levels.

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PMC8632470

Dugan had pretreated HEK293 cells with 10–100 μM concentrations of quercetin.

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PMC6379402

p-val)Cell viability change (p-val) TOPAZ1 PMID:234786284.04E-02 HLA-DQA2 PMID: 275398871.21E-01 HLA-DQA2 PMID:275398872.57E-02 ECT2L intOgen2.52E-029.52E-02 ECT2L intOgen2.44E-021.91E-01 PNMA6A 2.32E-024.04E-02 VCP PMID: 187987391.13E-024.04E-02 MAGEB16 PMID: 114547054.04E-02 ARID3A PMID: 224697801.38E-014.04E-02 ERIC...

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PMC9429973

Results: At the moment of detected Covid19 infection, 37pts (70%) had active MM, and 16pts (30%) were in the state of follow-up during remission of disease.

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PMC10530622

Despite numerous efforts to comprehend the mechanisms governing oxalate absorption and excretion processes, there remain gaps that need to be addressed (for review, see ).

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PMC9429973

Median age at diagnosis was 66 years and it did not differ in both groups.

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PMC10890307

Cells were incubated for 20 min at 37 °C, washed using BD wash buffer, and total DNA was stained with 7-amino-actinomycin D (7-AAD), followed by flow cytometric analysis.

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PMC8358176

In the final step, Ficoll density gradient centrifugation (Sigma, Germany) was employed for the isolation of the peripheral mononuclear cells (PBMCs) isolated and for the extraction of total RNA.

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PMC11585994

In this study, we employed generation 5 PAMAM (G5-PAMAM, henceforth referred to as G5) to encapsulate both sgc8 and siBCL11B, resulting in the formation of G5-sgc8-siBCL11B nanoparticles for targeted therapy of T-ALL.

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PMC2010673

Monoclonal antibody against an osteogenic-sarcoma cell line (791T) was prepared by production and cloning of a somatic-cell hybrid between the mouse myeloma P3-NS1 and spleen cells from 791T-immunized mice.

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PMC11727000

We chose to validate the data through experiments involving BRCA2.

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PMC11001582

Graph, mean ± s.e.m.,

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PMC9776316

In both A2780cisR and SKOV3cisR cell lines, treatment of cisplatin led to a significant increase of XRCC4 promoter activity; by contrast, mutation of cJUN binding site to XRCC4 promoter diminished the effect of cisplatin in the upregulating of XRCC4 promoter activity.

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PMC9776316

Platinum-based chemotherapy regimen has been the most actively used as a first-line treatment of ovarian cancer for decades .

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PMC9429973

The proportions of pts with ≥1 SAE and ≥1 AESI were 49.4% (228/462) and 28.8% (133/462), respectively.

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PMC8494202

Therefore, our study findings support that CKAP2L is associated with poor prognosis of glioma, can be used as an independent risk factor, and has diagnostic value.

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PMC10772747

Our research findings in the apoptosis assay demonstrated that EBE compounds exhibited strong potential in inducing apoptosis in breast cancer cells, with a total of 93.6% of cells undergoing apoptosis and 5.5% undergoing necrosis (Figure 5).

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PMC11300639

Ns, not significant.

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PMC11400680

Lastly, for the mAP50–95 scores (Figure 7F), the easy set was the highest, with a median (Q2) value of 0.46 (0.42±0.2), followed by the medium test set with a median (Q2) value of 0.25 (0.35±0.3), and the difficult test set with a median (Q2) value of 0.1 (0.19±0.2).

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PMC11342785

Across synMAP IDR-CORE chimeras, bundling efficiency (EC50) scaled with droplet formation activity in vitro (DDX4>FUS>LAF).

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PMC11474209

Cu/Au/Pt TNs-encapsulated DNA hydrogel colorimetric biosensorTap water3.0 ng LFor colorimetric MC-LR detection, Cu/Au/Pt TNs-encapsulated DNA hydrogel was created.

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PMC11116779

After 24, 48, 72, and 96 h, the plates were read with a SynergyH1 BioTek spectrophotometer (Agilent, Santa Clara, United States) at 490 nm.

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PMC11033180

Data are mean ± SEM, n = 8 cultures from 2 independent experiments.

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PMC6461034

For the latter cell line, driven by the serine/threonine kinase BRAF (not detected by pTyr‐based phosphoproteomics), downstream driver targets in the MEK‐ERK pathway (MAP2K1, MAP2K2, MAPK1, MAPK3) are highlighted (Fig 2B).

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PMC5034105

In addition to the few cell lines previously reported, our study has identified a broad range of cell lines that are suitable for growing ZIKV as an alternative diagnostic tool in clinical virology laboratories.

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PMC11615743

As a chiral molecule of D‐DNA, L‐DNA exhibits high stability in serum and does not hybridize with complementary D‐DNA sequences in the environment, making it an ideal candidate for diagnostic and therapeutic applications.

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PMC9429973

The majority of patients were treated by phlebotomy with 1 or 2 units per month, before starting hydroxy urea.

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PMC11604768

This study introduces an MPRA library designed to simultaneously screen thousands of candidate synthetic promoters in mammalian cells.

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PMC11269933

The phosphorylation at this site enhanced substrate binding and increases PK enzyme activity, thereby promoting ATP production to aid in heat-induced damage repair.

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PMC11335267

Coexpression of Alx3 with either POMC- or AgRP-neurons was assessed using coronal sections (20 μm) spanning the entire arcuate nucleus (bregma − 1.1 to -2.6 mm), after incubation with the Alx3 antibody and secondary Alexa Fluor-555 or Alexa Fluor-488 rabbit antibodies (Invitrogen).

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PMC10926885

Prostate cancer development has also been shown to be regulated by axonemal dynein heavy chain 8.

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PMC11774112

After 72 h, 85.6% of the DTIC was released from the DTIC-loaded micelles.

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PMC11609529

H292 cells, which express a different fusion protein, CRTC1-MAML2, were used as a control.

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PMC10033453

Assessment of VMG efficacy in syngeneic model of sarcoma WEHI 164 (A) Individual murine tumor volumes after treatment.

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PMC10852540

The primers used to investigate the changes in the expression of these genes are given below in 5’-3’ order.

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PMC10823017

mRNA levels of PKC-ι, PKC-ζ, and c-Myc for the siRNA (PKC-ι and PKC-ζ) treated (A) 786-0 and (B) Caki-1 cells against respective control samples based on quantitative real-time PCR (qPCR).

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PMC11615101

The antibody (α-Taxilin) was immobilized (3h, RT) on agarose beads,28 washed, and eluted in native elution buffer (provided).

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