OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC10758402	, F4/80-BUV605 (1:100, BioLegend, CA, USA, Cat. #	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ",", "F4/80-BUV605", "(", "1:100", ",", "BioLegend", ",", "CA", ",", ...
PMC8357004	The most important decision that every mammalian live-cell must make is whether to continue cell division or to exit the cell cycle and reach a quiescent state.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10006224	The NIPBL KD plot shown corresponds to the experiment co-depleting NIPBL and CTCF.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "NIPBL", "KD", "plot", "shown", "corresponds", "to", "the", "ex...
PMC11406030	More importantly, novel LMTK3BPs represent potential safe treatment options, either alone or in combination with therapies, for OC.Epithelial ovarian cancer is a deadly gynecological cancer that is currently regarded as one of the most common cancer types among women.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11765988	The third mechanism that may explain the pathogenesis of drug-induced sarcoidosis (DISR) can be divided into two phases.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "third", "mechanism", ...
PMC10831439	Further, the proliferation of CD19-CAR-iNKT cells was tested during checkpoint inhibition on antigen encounter.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Further", ",", "the", "proliferation", "of", "CD19-CAR-iNKT", ...
PMC9429973	Multivariate analysis showed that HLA mismatch did not affect OS, RFS or GRFS (P = 0.654, P = 0.811, and P = 0.114, respectively).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3995603	The blood samples were collected in a microtainer (Becton, Dickinson and Company, NJ, USA) containing K2-EDTA.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "blood", "s...
PMC11055323	Two-sided Wilcoxon test adjusted for multiple comparisons.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Two-sided", "Wilcoxon", "test", "adjusted", "for", "multiple", "comparisons", "." ] } ]
PMC9429973	CAN106 is a novel anti-C5 monoclonal antibody designed for optimal pH-dependent binding to C5 and enhanced binding to FcRN to increase intracellular recycling and prolong its half-life.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11724582	HFL1 cells were stimulated with 10 ng/mL TGF-β1 for 24–48 h, after which they were passaged 2–3 times. (	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "HFL1", "cells", "we...
PMC11791264	H, Western blot was performed with the indicated antibodies in SKOV3 cells treated as in F and G. Given that SETD7 promoted OC cell proliferation and migration (Fig. 1), we further investigated whether SETD7-mediated cell phenotypes depended on the methylation of LC3B.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11547972	A multi-well ELISA reader determined the absorbance at 570 nm (Tecan Infinite M200, Männedorf, Switzerland).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "multi-well", "ELISA", "reade...
PMC11585565	This suggests that the pathogenic mechanism underlying Jalili syndrome associated with these variants likely involves decreased mRNA and/or protein stability, rather than mislocalization.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11790971	Higher MOCs between those channels were reported in cell line A, meaning that the co-occurrence of high NAD(P)H intensity and long NAD(P)H mean lifetime was more obvious in those cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11683130	These chemokines include LCN2, CXCL8, and CXCL1, which in turn promote neutrophil migration to the skin (154).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "che...
PMC11518994	PAX5 expression was evaluated in CASE B (A), in the wild-type mother (B), control lymphoblastoid cell line (C); only the wild-type PAX5 protein (42 kD) was detected.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11472569	Diverse cargo types in EV-mediated transfer of MDR EV: Extracellular vesicle; MDR: multidrug resistance; DDP: cisplatin; TrpC5: transient receptor potential channel 5; NSCLC: non-small cell lung cancer; PDGFRβ: platelet-derived growth factor receptor-beta; HGF: hepatocyte growth factor.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9545714	A RIN number of 10 indicates perfect RNA quality; a RIN number of 1 indicates degraded RNA.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "RIN", "number", "of", "10", ...
PMC11424574	Accumulating evidence indicates that excess uPA degrades the extracellular matrix, which is associated with the metastatic process in a variety of solid tumors, including breast, uterine cervix, pancreas, ovary, and glioma .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7723249	In fact, the level of released IL-8 by HAZV and CCHFV infected moDCs are similar (Fig 4).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "fact", ",", "the...
PMC11593031	It is widely recognized that the tetraploidization of cell lines in long-term culture is a common phenomenon.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "is", "widely", "recognized", "that", ...
PMC11703992	High intensity of NFKB1 and NFKB2 suggested high activation of NF-κB pathway in DDIT4+ Memory T cells in GCA.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "High", "intensity", "of", ...
PMC8567602	All BAF subunits were assembled into a single pBig2 vector prior to transfection into EXPI293 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "BAF", "subunits", "were", "assembled", "into", ...
PMC9429973	59 had a FLT3 ITD and 22 a FLT3-TKD (and 4 had both).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "59", "had", "a", "FLT3", "ITD", "and", "22", "a", ...
PMC11763533	The spectral shift (ΔλpH6–8) and the bandwidth [half-band] caused by these pH changes, were higher for Amydetes luciferase (26 and 24 nm, respectively), and lower for Crt (10 and 19 nm, respectively) and Mac (16 and 6 nm, respectively) (Figure 4 and Table 1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8728081	However, the concerns regarding the use of mercury cannot be ignored as it is a potential neurotoxin even at lower doses.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However...
PMC11371747	In general, modulation by l-LV is similar to dl-LV, while d-LV does not modulate, in agreement with data in a CCRF-CEM cell line (Zittoun et al., 1991).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", ...
PMC10818573	Based on these results, we concluded that the primer dimer in the reaction system produced false-positive bands on the test strips; therefore, a probe was introduced.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11628904	Subsequent keratinocyte swelling is a pro‐migratory signal. ,	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Subsequent", "keratinocyte", "swelling", "is", "a", "pro‐migratory", "signal", ".", "," ] } ]
PMC11782780	Not applicable.	[ { "tags": [ "O", "O", "O" ], "tokens": [ "Not", "applicable", "." ] } ]
PMC9429973	Unfortunately, the research on the improvement of paeoniflorin on Bortezomib-induced peripheral neuropathy (BIPN) is still relatively rare.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Unfortunately", ",", "the", ...
PMC10812665	We showed severe consequences on AA and their metabolites (Asp most down-regulated; Lys metabolites most up-regulated).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "showed", "severe", "consequ...
PMC6771295	For experiments where cells were transiently transfected, CD20 expressing vector was co-transfected with other plasmids and used as an indicator of transfection efficiency.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC8978939	Representative picture of nude mice and the tumors developed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Representative", "picture", "of", "nude", "mice", "and", "the", "tumors", "developed", "." ] } ]
PMC9429973	Methods: NCT03590574 is multi-centre, single-arm study of AUTO4 with a phase I dose escalation component and a phase II expansion cohort.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Methods...
PMC8526701	G WT and PUMA-KO GIST-882 or GIST-T1 cells were treated with 0.5 μM GSK602 for 24 h. Indicated protein level was analyzed by western blotting.	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC10291556	To confirm that enDCF had formed, proton NMR spectra were measured (Figures S1 and S2).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "confirm", "that", "enDCF", "had"...
PMC10587429	NCSS, LLC).	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "NCSS", ",", "LLC", ")", "." ] } ]
PMC11635519	The HEK293 cell line was obtained from the American Type Culture Collection (ATCC).	[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "HEK293", "cell", "line", "was", "obtained", ...
PMC8345486	PI incorporation into cells (necrosis) without annexin V-FITC binding to the cellular membrane indicated necrotic cells, annexin V-FITC binding without PI staining indicated early apoptosis, and annexin V-FITC plus PI staining indicated late apoptosis, that is, necrosis as a final result of apoptosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11798926	We determined that there is a significantly higher correlation coefficient between SynDIG4 + GluA1 puncta than either SynDIG4 + GluK2 or SynDIG4 + GluA2 puncta.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10955424	The involvement of ERK1/2 in soluble factor-mediated chemoresistance was inconclusive and was a cell type-specific phenomenon .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "involvement", "of", "ERK1/2", "in", "soluble", ...
PMC11721295	Interestingly, Apoe, another marker of immunosuppression, was upregulated in the OFF group (Figure 4D).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Interestingly", ",", "Apoe", ",",...
PMC11225860	Cell-by-cell analysis counts both red (cyan circle) and green cells (blue circle), while excluding dead and colorless cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cell-by...
PMC11126803	The VM formation experiments results showed that overexpressed LncRNA-SERB can increase VM formation, while knocking down ERβ can effectively reverse the LncRNA-SERB increased VM formation (Fig. 3B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11467964	After that, PCA was employed to reveal difference between distinct groups in the transcription of the BMRGs, and the result showed a significant difference as predicted (Figure 2C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11587541	Furthermore, we categorized our data into various subtypes like type0, type1, type2, type3, type4 and performed the sub group analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11617590	Therefore, when SFN was treated with 25 μM for 24 h, it induced early cell death, but there was not enough time and concentration to decrease the number of viable cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11594806	They discovered that this intracellular CD73 interacts with major vault protein (MVP) to activate the SRC-AKT pathway.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "They", "discovered", "that", "thi...
PMC11746948	Data are presented as mean ± SD.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "are", "presented", "as", "mean", "±", "SD", "." ] } ]
PMC9429973	INHERENT aims to recruit over 30,000 hemoglobinopathy patients, which is larger than any previous GWAS in the field.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "INHERENT", "aims", "to", "recruit...
PMC11591038	The T cell-specific knockout of HIF-1α in mice displays more severe colonic inflammation induced by dextran sodium sulfate; notably, hypoxia-induced HIF-1 is required for Treg activation but suppresses Th17 activation .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11391695	Following that, the cells were subjected to treatment using probes (Ribobio, China) that contained either TERT or GAPDH in accordance with the guidelines provided in the fluorescence in situ hybridization kit (GenePharma, China).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	71 people had COVID-19, 258 didn’t.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "71", "people", "had", "COVID-19", ",", "258", "did", "n’t", "." ] } ]
PMC11222184	The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) and Polyvinylidene difluoride (PVDF) membrane (741260) were provided by Macherey–Nagel.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "3-(4,...
PMC9512971	However, in a repeated-dose toxicity study in dogs, camostat 300 mg/kg decreased body weight and food intake; induced vomiting and effects on the gastrointestinal tract, including gastrointestinal injury; and caused death, with a no-observed adverse effect level (NOAEL) of 100 mg/kg .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11352666	There is a slight male predominance, and EWS most commonly affects white non-Hispanic and Hispanic populations.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "There", "is", "a", "slight", "male", "predo...
PMC9693627	After incubation at 37 °C for 45 min the medium was replaced with fully supplemented DMEM containing cold methionine and the cells were harvested.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973	Median OS since MM diagnosis and since SPM detection were 63 months and 8.5 months, respectively (Figure 1). (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Median", "OS...
PMC11655536	Primary cells were treated with HA at 10 µM and 20 µM for 48 h and tested for viability.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Primary", "cells", "were", "treat...
PMC8916024	To study species diversity among the samples, a total of 1,079,092 effective tags were obtained from all samples using Uparse software, and a total of 46,011 valid OTUs were obtained with 97% identity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	For TSS reduction, the sample size (N=20) in REFINE was considered too small to perform a meaningful ITC; however, the absolute response rates for TSS reduction were similar across the 2 groups (29% [16/56] in the FEDR group and 30% [6/20] in the NAV+RUX group).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11422150	The results revealed an increase in monocytic-myeloid-derived suppressor cells (M-MDSCs), implicated in immune cell regulation, in the untreated SCI group (4,650± 433 cells, P = 0.012) compared with the normal group (2,420± 187 cells, Figure 6B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11471157	Outer surface after processing. (	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Outer", "surface", "after", "processing", ".", "(" ] } ]
PMC9436459	In the antiviral investigation of Morus spp.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "the", "antiviral", "investigation", "of", "Morus", "spp", "." ] } ]
PMC11476666	The sorting of A549 cells showed that 1.4% of cells were mildly positive for Hoechst 33342 dye, indicative of the SP phenotype, which was reduced in the presence of Verapamil, an inhibitor of ABC subfamily efflux pumps.	[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9370419	According to our results, the sex hormone molecular estradiol benzoate could reduce intracellular HBx levels.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "According", "to", "our", "results", ",", "the", ...
PMC10212663	The Coefi and Expi values represented, respectively, each gene's risk coefficient and expression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "Coefi", "and", "Expi", "values", "represented",...
PMC10213179	Figure 4Binding specificity of the selected aptamer(A) Binding curve of ATOP toward recombinant human EphA2 evaluated by SPR.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Figure", "4Binding", "specificity", ...
PMC11001582	To further verify our results, we evaluated one of the most altered ECM proteins in the proteomics analysis, COL6A1, in (GR)400 and (PR)400 mice.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11400680	Figure 1 illustrates some examples of microscopic images representing each level of difficulty in the test set.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Figure", "1", "illustrates", "some", "examples", ...
PMC7553912	The mice had free access to food (MF; Oriental Yeast, Tokyo, Japan) and water.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "mice", "had", "free", ...
PMC11768927	Additionally, Bayne et al. showed that the resistant prostate cancer cell line, PC3, retained an active IFN-I response, thereby constitutively expressing interferon-stimulated genes (ISGs).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7305184	The standard procedure to obtain a “resistant” cell line takes a few months, with low administrated doses or treatment and cells are allowed to recover in drug-free media.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The recently published DESTINY trial (Clark et al., Lancet Haematol, 2019; NCT 01804985) showed that TKI dose reduction prior to cessation can proactively increase the fraction of patients to remain in sustained TFR.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6160470	of 3 individual experiments and normalized to verapamil. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "of", "3", "individual", "experiments", "and", "normalized", "to", "verapamil", ".", "(" ] } ]
PMC9822769	However, this may not be sufficient to guarantee in vivo reduction, as the kinetic characteristics of chemical reduction play an important role, especially in the case of an inner-sphere mechanism .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC2193049	In brief, PBL were stained with tetramers of HLA-A*0201–β2-microglobulin containing the peptide MAGE-3271–279.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "brief", ",", "PBL", "were", "stained", "with", "tetramers"...
PMC11507371	Overall, numerous genes respond to NF-κB, including those encoding cytokines (e.g., IL-1, IL-6, chemokine (C-X-C motif) ligand (CXCL8), transforming growth factor (TGFβ), and TNFα), as well as critical proteins such as cell adhesion molecules, anti-apoptotic proteins, matrix metalloproteinases, and other enzymes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10998613	Schematic showing the formation of CXCR4 and β2AR heteromultimers in COS-7 and DKO MDA-MB-231 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "B-CellLine", "O", "O" ], "tokens": [ "Schematic", "showing", "the", "formation", "...
PMC9429973	Cytogenetic study showed the presence of a t (9.22) in all cases, which was isolated in 1 case.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cytogenetic", "study", ...
PMC9429973	Although preliminary, these results provided evidence and support the use of ZR in PVRL.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Although", "preliminary", ",", "these", "results", "provided", ...
PMC11066331	Established matrix of spectral data was used for further multivariate statistical methods and development of selected classifiers.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Established", "matrix", "of", "spectral", "data",...
PMC9429973	60-day mortality in frontline was 0.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "60-day", "mortality", "in", "frontline", "was", "0", "." ] } ]
PMC11467964	Kaplan–Meier curves for OS of the two gene subtypes (log‐rank tests, p < .05). (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Kaplan", "–", "Meier", ...
PMC11046454	Compared with single-stranded DNA, a 3-fold enhancement on the binding efficiency between FITC-labeled DNA and anti-FITC scFv was obtained (Figure 3H).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11783017	The generated M1-like macrophages and mature DCs further activate T cells for tumor immunotherapy, resulting in a significant increase in the ratio of helper T cells (CD4) and cytotoxic T cells (CD8) after administration of Cis/Mn/NH@PGP (Fig. S32).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11714165	Previous studies have reported that the oligo(aspartic acid)s, alendronate, and pamidronate can promote the bone‐targeting capability of therapeutics and materials.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Previous", "...
PMC3164356	One challenge in therapeutic protein production is the avoidance of immunogenic responses that can arise from foreign glycan structures.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "One", "challenge", "in", "therape...
PMC11792766	The lactate dehydrogenase (LDH) assay materials comprised 2× LDH assay buffer, 2‐(4‐iodophenyl)‐3‐(4‐nitrophenyl)‐5‐phenyltetrazolium chloride 95% (INT) (VWR, Cat.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9119314	Taken together, these data suggest that 2 may be a lead to novel antimalarial agents, but as chemical synthesis is not environmentally friendly, an alternative approach utilizing C. sanguinolenta roots is desirable.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11574029	Therefore, identifying new oncogenes that drive the aggressive progression of BLCA and elucidating the underlying molecular mechanisms is crucial.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "identifyin...
PMC11366496	The data were reported as the Mean ± SD, derived from three autonomous experiments. *	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "data", "were", "reported", "as", "the", "...
PMC11352746	The IncuCyte system, despite its ease of use, automated capabilities, and suitability for long-term studies, has certain limitations compared to other live-cell imaging systems.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9318744	Using the ACE2plusC3 system, we can begin to address these questions about the omicron variant and future variants.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Using", "the", "ACE2plusC3", "sys...
PMC10944868	Chemical structures were imported in swissADME and pkCSM tools to calculate molecular as well as ADME properties of the compounds (Daina et al., 2017; Bakchi et al., 2022).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9014716	A growing number of studies have demonstrated that P-gp is involved in resistance to chemotherapeutic agents by pumping anti-tumor drugs out of the cell and decreasing the accumulated concentration in tumor cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10595704	Although NP has been extensively studied as a pollutant in marine and water environments, its potential detrimental effects, when present in the atmosphere, are still poorly investigated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11481779	Thus, multiple efforts have been made to predict the spatial organisation of chromatin in the nucleus using various machine-learning models.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thus", ",", "mult...

PMC10758402

, F4/80-BUV605 (1:100, BioLegend, CA, USA, Cat. #

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PMC8357004

The most important decision that every mammalian live-cell must make is whether to continue cell division or to exit the cell cycle and reach a quiescent state.

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PMC10006224

The NIPBL KD plot shown corresponds to the experiment co-depleting NIPBL and CTCF.

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PMC11406030

More importantly, novel LMTK3BPs represent potential safe treatment options, either alone or in combination with therapies, for OC.Epithelial ovarian cancer is a deadly gynecological cancer that is currently regarded as one of the most common cancer types among women.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11765988

The third mechanism that may explain the pathogenesis of drug-induced sarcoidosis (DISR) can be divided into two phases.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "third", "mechanism", ...

PMC10831439

Further, the proliferation of CD19-CAR-iNKT cells was tested during checkpoint inhibition on antigen encounter.

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PMC9429973

Multivariate analysis showed that HLA mismatch did not affect OS, RFS or GRFS (P = 0.654, P = 0.811, and P = 0.114, respectively).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC3995603

The blood samples were collected in a microtainer (Becton, Dickinson and Company, NJ, USA) containing K2-EDTA.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "blood", "s...

PMC11055323

Two-sided Wilcoxon test adjusted for multiple comparisons.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Two-sided", "Wilcoxon", "test", "adjusted", "for", "multiple", "comparisons", "." ] } ]

PMC9429973

CAN106 is a novel anti-C5 monoclonal antibody designed for optimal pH-dependent binding to C5 and enhanced binding to FcRN to increase intracellular recycling and prolong its half-life.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11724582

HFL1 cells were stimulated with 10 ng/mL TGF-β1 for 24–48 h, after which they were passaged 2–3 times. (

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PMC11791264

H, Western blot was performed with the indicated antibodies in SKOV3 cells treated as in F and G. Given that SETD7 promoted OC cell proliferation and migration (Fig. 1), we further investigated whether SETD7-mediated cell phenotypes depended on the methylation of LC3B.

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PMC11547972

A multi-well ELISA reader determined the absorbance at 570 nm (Tecan Infinite M200, Männedorf, Switzerland).

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PMC11585565

This suggests that the pathogenic mechanism underlying Jalili syndrome associated with these variants likely involves decreased mRNA and/or protein stability, rather than mislocalization.

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PMC11790971

Higher MOCs between those channels were reported in cell line A, meaning that the co-occurrence of high NAD(P)H intensity and long NAD(P)H mean lifetime was more obvious in those cells.

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PMC11683130

These chemokines include LCN2, CXCL8, and CXCL1, which in turn promote neutrophil migration to the skin (154).

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PMC11518994

PAX5 expression was evaluated in CASE B (A), in the wild-type mother (B), control lymphoblastoid cell line (C); only the wild-type PAX5 protein (42 kD) was detected.

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PMC11472569

Diverse cargo types in EV-mediated transfer of MDR EV: Extracellular vesicle; MDR: multidrug resistance; DDP: cisplatin; TrpC5: transient receptor potential channel 5; NSCLC: non-small cell lung cancer; PDGFRβ: platelet-derived growth factor receptor-beta; HGF: hepatocyte growth factor.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9545714

A RIN number of 10 indicates perfect RNA quality; a RIN number of 1 indicates degraded RNA.

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PMC11424574

Accumulating evidence indicates that excess uPA degrades the extracellular matrix, which is associated with the metastatic process in a variety of solid tumors, including breast, uterine cervix, pancreas, ovary, and glioma .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC7723249

In fact, the level of released IL-8 by HAZV and CCHFV infected moDCs are similar (Fig 4).

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PMC11593031

It is widely recognized that the tetraploidization of cell lines in long-term culture is a common phenomenon.

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PMC11703992

High intensity of NFKB1 and NFKB2 suggested high activation of NF-κB pathway in DDIT4+ Memory T cells in GCA.

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PMC8567602

All BAF subunits were assembled into a single pBig2 vector prior to transfection into EXPI293 cells.

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PMC9429973

59 had a FLT3 ITD and 22 a FLT3-TKD (and 4 had both).

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PMC11763533

The spectral shift (ΔλpH6–8) and the bandwidth [half-band] caused by these pH changes, were higher for Amydetes luciferase (26 and 24 nm, respectively), and lower for Crt (10 and 19 nm, respectively) and Mac (16 and 6 nm, respectively) (Figure 4 and Table 1).

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PMC8728081

However, the concerns regarding the use of mercury cannot be ignored as it is a potential neurotoxin even at lower doses.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However...

PMC11371747

In general, modulation by l-LV is similar to dl-LV, while d-LV does not modulate, in agreement with data in a CCRF-CEM cell line (Zittoun et al., 1991).

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PMC10818573

Based on these results, we concluded that the primer dimer in the reaction system produced false-positive bands on the test strips; therefore, a probe was introduced.

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PMC11628904

Subsequent keratinocyte swelling is a pro‐migratory signal. ,

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PMC11782780

Not applicable.

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PMC9429973

Unfortunately, the research on the improvement of paeoniflorin on Bortezomib-induced peripheral neuropathy (BIPN) is still relatively rare.

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PMC10812665

We showed severe consequences on AA and their metabolites (Asp most down-regulated; Lys metabolites most up-regulated).

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PMC6771295

For experiments where cells were transiently transfected, CD20 expressing vector was co-transfected with other plasmids and used as an indicator of transfection efficiency.

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PMC8978939

Representative picture of nude mice and the tumors developed.

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PMC9429973

Methods: NCT03590574 is multi-centre, single-arm study of AUTO4 with a phase I dose escalation component and a phase II expansion cohort.

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PMC8526701

G WT and PUMA-KO GIST-882 or GIST-T1 cells were treated with 0.5 μM GSK602 for 24 h. Indicated protein level was analyzed by western blotting.

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PMC10291556

To confirm that enDCF had formed, proton NMR spectra were measured (Figures S1 and S2).

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PMC10587429

NCSS, LLC).

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PMC11635519

The HEK293 cell line was obtained from the American Type Culture Collection (ATCC).

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PMC8345486

PI incorporation into cells (necrosis) without annexin V-FITC binding to the cellular membrane indicated necrotic cells, annexin V-FITC binding without PI staining indicated early apoptosis, and annexin V-FITC plus PI staining indicated late apoptosis, that is, necrosis as a final result of apoptosis.

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PMC11798926

We determined that there is a significantly higher correlation coefficient between SynDIG4 + GluA1 puncta than either SynDIG4 + GluK2 or SynDIG4 + GluA2 puncta.

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PMC10955424

The involvement of ERK1/2 in soluble factor-mediated chemoresistance was inconclusive and was a cell type-specific phenomenon .

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PMC11721295

Interestingly, Apoe, another marker of immunosuppression, was upregulated in the OFF group (Figure 4D).

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PMC11225860

Cell-by-cell analysis counts both red (cyan circle) and green cells (blue circle), while excluding dead and colorless cells.

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PMC11126803

The VM formation experiments results showed that overexpressed LncRNA-SERB can increase VM formation, while knocking down ERβ can effectively reverse the LncRNA-SERB increased VM formation (Fig. 3B).

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PMC11467964

After that, PCA was employed to reveal difference between distinct groups in the transcription of the BMRGs, and the result showed a significant difference as predicted (Figure 2C).

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PMC11587541

Furthermore, we categorized our data into various subtypes like type0, type1, type2, type3, type4 and performed the sub group analysis.

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PMC11617590

Therefore, when SFN was treated with 25 μM for 24 h, it induced early cell death, but there was not enough time and concentration to decrease the number of viable cells.

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PMC11594806

They discovered that this intracellular CD73 interacts with major vault protein (MVP) to activate the SRC-AKT pathway.

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PMC11746948

Data are presented as mean ± SD.

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PMC9429973

INHERENT aims to recruit over 30,000 hemoglobinopathy patients, which is larger than any previous GWAS in the field.

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PMC11591038

The T cell-specific knockout of HIF-1α in mice displays more severe colonic inflammation induced by dextran sodium sulfate; notably, hypoxia-induced HIF-1 is required for Treg activation but suppresses Th17 activation .

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PMC11391695

Following that, the cells were subjected to treatment using probes (Ribobio, China) that contained either TERT or GAPDH in accordance with the guidelines provided in the fluorescence in situ hybridization kit (GenePharma, China).

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PMC9429973

71 people had COVID-19, 258 didn’t.

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PMC11222184

The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) and Polyvinylidene difluoride (PVDF) membrane (741260) were provided by Macherey–Nagel.

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PMC9512971

However, in a repeated-dose toxicity study in dogs, camostat 300 mg/kg decreased body weight and food intake; induced vomiting and effects on the gastrointestinal tract, including gastrointestinal injury; and caused death, with a no-observed adverse effect level (NOAEL) of 100 mg/kg .

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PMC11352666

There is a slight male predominance, and EWS most commonly affects white non-Hispanic and Hispanic populations.

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PMC9693627

After incubation at 37 °C for 45 min the medium was replaced with fully supplemented DMEM containing cold methionine and the cells were harvested.

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PMC9429973

Median OS since MM diagnosis and since SPM detection were 63 months and 8.5 months, respectively (Figure 1). (

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PMC11655536

Primary cells were treated with HA at 10 µM and 20 µM for 48 h and tested for viability.

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PMC8916024

To study species diversity among the samples, a total of 1,079,092 effective tags were obtained from all samples using Uparse software, and a total of 46,011 valid OTUs were obtained with 97% identity.

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PMC9429973

For TSS reduction, the sample size (N=20) in REFINE was considered too small to perform a meaningful ITC; however, the absolute response rates for TSS reduction were similar across the 2 groups (29% [16/56] in the FEDR group and 30% [6/20] in the NAV+RUX group).

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PMC11422150

The results revealed an increase in monocytic-myeloid-derived suppressor cells (M-MDSCs), implicated in immune cell regulation, in the untreated SCI group (4,650± 433 cells, P = 0.012) compared with the normal group (2,420± 187 cells, Figure 6B).

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PMC11471157

Outer surface after processing. (

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PMC9436459

In the antiviral investigation of Morus spp.

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PMC11476666

The sorting of A549 cells showed that 1.4% of cells were mildly positive for Hoechst 33342 dye, indicative of the SP phenotype, which was reduced in the presence of Verapamil, an inhibitor of ABC subfamily efflux pumps.

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PMC9370419

According to our results, the sex hormone molecular estradiol benzoate could reduce intracellular HBx levels.

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PMC10212663

The Coefi and Expi values represented, respectively, each gene's risk coefficient and expression.

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PMC10213179

Figure 4Binding specificity of the selected aptamer(A) Binding curve of ATOP toward recombinant human EphA2 evaluated by SPR.

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PMC11001582

To further verify our results, we evaluated one of the most altered ECM proteins in the proteomics analysis, COL6A1, in (GR)400 and (PR)400 mice.

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PMC11400680

Figure 1 illustrates some examples of microscopic images representing each level of difficulty in the test set.

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PMC7553912

The mice had free access to food (MF; Oriental Yeast, Tokyo, Japan) and water.

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PMC11768927

Additionally, Bayne et al. showed that the resistant prostate cancer cell line, PC3, retained an active IFN-I response, thereby constitutively expressing interferon-stimulated genes (ISGs).

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PMC7305184

The standard procedure to obtain a “resistant” cell line takes a few months, with low administrated doses or treatment and cells are allowed to recover in drug-free media.

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PMC9429973

The recently published DESTINY trial (Clark et al., Lancet Haematol, 2019; NCT 01804985) showed that TKI dose reduction prior to cessation can proactively increase the fraction of patients to remain in sustained TFR.

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PMC6160470

of 3 individual experiments and normalized to verapamil. (

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PMC9822769

However, this may not be sufficient to guarantee in vivo reduction, as the kinetic characteristics of chemical reduction play an important role, especially in the case of an inner-sphere mechanism .

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PMC2193049

In brief, PBL were stained with tetramers of HLA-A*0201–β2-microglobulin containing the peptide MAGE-3271–279.

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PMC11507371

Overall, numerous genes respond to NF-κB, including those encoding cytokines (e.g., IL-1, IL-6, chemokine (C-X-C motif) ligand (CXCL8), transforming growth factor (TGFβ), and TNFα), as well as critical proteins such as cell adhesion molecules, anti-apoptotic proteins, matrix metalloproteinases, and other enzymes.

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PMC10998613

Schematic showing the formation of CXCR4 and β2AR heteromultimers in COS-7 and DKO MDA-MB-231 cells.

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PMC9429973

Cytogenetic study showed the presence of a t (9.22) in all cases, which was isolated in 1 case.

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PMC9429973

Although preliminary, these results provided evidence and support the use of ZR in PVRL.

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PMC11066331

Established matrix of spectral data was used for further multivariate statistical methods and development of selected classifiers.

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PMC9429973

60-day mortality in frontline was 0.

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PMC11467964

Kaplan–Meier curves for OS of the two gene subtypes (log‐rank tests, p < .05). (

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PMC11046454

Compared with single-stranded DNA, a 3-fold enhancement on the binding efficiency between FITC-labeled DNA and anti-FITC scFv was obtained (Figure 3H).

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PMC11783017

The generated M1-like macrophages and mature DCs further activate T cells for tumor immunotherapy, resulting in a significant increase in the ratio of helper T cells (CD4) and cytotoxic T cells (CD8) after administration of Cis/Mn/NH@PGP (Fig. S32).

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PMC11714165

Previous studies have reported that the oligo(aspartic acid)s, alendronate, and pamidronate can promote the bone‐targeting capability of therapeutics and materials.

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PMC3164356

One challenge in therapeutic protein production is the avoidance of immunogenic responses that can arise from foreign glycan structures.

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PMC11792766

The lactate dehydrogenase (LDH) assay materials comprised 2× LDH assay buffer, 2‐(4‐iodophenyl)‐3‐(4‐nitrophenyl)‐5‐phenyltetrazolium chloride 95% (INT) (VWR, Cat.

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PMC9119314

Taken together, these data suggest that 2 may be a lead to novel antimalarial agents, but as chemical synthesis is not environmentally friendly, an alternative approach utilizing C. sanguinolenta roots is desirable.

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PMC11574029

Therefore, identifying new oncogenes that drive the aggressive progression of BLCA and elucidating the underlying molecular mechanisms is crucial.

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PMC11366496

The data were reported as the Mean ± SD, derived from three autonomous experiments. *

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PMC11352746

The IncuCyte system, despite its ease of use, automated capabilities, and suitability for long-term studies, has certain limitations compared to other live-cell imaging systems.

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PMC9318744

Using the ACE2plusC3 system, we can begin to address these questions about the omicron variant and future variants.

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PMC10944868

Chemical structures were imported in swissADME and pkCSM tools to calculate molecular as well as ADME properties of the compounds (Daina et al., 2017; Bakchi et al., 2022).

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PMC9014716

A growing number of studies have demonstrated that P-gp is involved in resistance to chemotherapeutic agents by pumping anti-tumor drugs out of the cell and decreasing the accumulated concentration in tumor cells.

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PMC10595704

Although NP has been extensively studied as a pollutant in marine and water environments, its potential detrimental effects, when present in the atmosphere, are still poorly investigated.

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PMC11481779

Thus, multiple efforts have been made to predict the spatial organisation of chromatin in the nucleus using various machine-learning models.

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