Datasets:
OTAR3088
/
BioData-CellLine_annotated

Dataset card Data Studio Files
xet
 Community
1
PMCID
string
Sentences
string
ner
list
PMC11725127
As shown in Fig. 6C and D, the cells overexpressing USP2 showed partial resistance to GA-induced viability reduction and KRAS degradation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "As", "shown"...
PMC10899471
These findings highlight the miR-939-3p/BATF2 axis as a promising therapeutic target for sarcoma patients.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "findings", "highlight", "the", "miR-939", "-"...
PMC11551844
TLC revealed that the precipitates were similar.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "TLC", "revealed", "that", "the", "precipitates", "were", "similar", "." ] } ]
PMC9429973
Pts with t(4;14), t(14;16), gain 1q, t(14;20), plasmablastic leukemia and/or del(17p13) were classified as HRC.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Pts", ...
PMC9429973
Image: Summary/Conclusion: High engraftment in this trial compares favorably to other clinical trials of SCD gene therapy which have observed marked decreases in VCN shortly after infusion and is particularly significant in the setting of RIC, where a population of patients’ unmodified HSCs remain and compete with the ...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3681794
HIF-1 function in U2OS cells was inhibited by transient transfection of a dominant negative HIF vector (DN-HIF) expressing a truncated HIF-1α which lacks the trans-activation domain.
[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Selected mutations are associated with changes in ROTEM parameters.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Selected", "mutations", "are", "associated", "with", "changes", "in", "ROTEM", "parameters", "." ] } ...
PMC11420784
The LC3-II signal densities were normalized to that of GAPDH.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "LC3-II", "signal", "densities", "were", "normalized", "to", "that", "of", "GAPDH", ...
PMC8193046
The statistical distribution of certain substructures that occurred in class 7 or class 4–6 molecules in the initial data set of 1,049 compounds needs revision and re-evaluation, taking the results of the present study into account.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11490153
+ low sensitivity (1–2), ++ mild sensitivity (2–3), +++ high sensitivity (3–6), ++++ indicates very high sensitivity (6< ) qPCR analysis of Bax and Bcl-2 expression in MDA-MB-231 cells under normoxic and hypoxic conditions A Bax/Bcl-2 ratio < 1.00 indicates cancer-resistant cells, and a Bax/Bcl-2 > 1.00 indicates cance...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11748335
The two-tailed t-test was used (***p < 0.001, **p < 0.01, *p < 0.05, NS = not significant) in (A, F and G) To delve deeper into the dynamics of long LOCKs in the context of cancer, we paired tumor cells with corresponding normal cells to establish three categories of long LOCKs: those that were lost in tumor compared t...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11659921
Methylation probes linked to TNFSF11 and their chromosomal distribution. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Methylation", "probes", "linked", "to", "TNFSF11", "and", "their", "chromosomal", "distribution", ...
PMC11568601
In addition, cleaved caspase-3 and cleaved PARP1, apoptosis-associated proteins, were also detected to be highly expressed (Fig. 7A).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", ...
PMC9429973
Siremadlin + venetoclax has shown durable antitumor responses in p53-wild-type AML patient-derived xenograft models (Wang Y, Cancer Res, 2019).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Siremad...
PMC10847511
The discrepancy in drug response between cancer cell lines and clinical tumors observed here can be attributed to several factors.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "discrepancy", "in", ...
PMC11730000
The membrane was blocked for 1 h to reduce non-specific binding using 5% non-fat dry milk in TBS-T buffer (Tris-buffered saline with 0.1% tween-20).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
The FDA approved the use of ruxolitinib, a JAK1/2 kinase inhibitor, that proved to be effective in reducing symptoms and spleen volume, but not in inducing complete molecular remission.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11155445
Most of the compounds exhibit weak activity, while compound (162c) showed 100% activity at conc.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Most", "of", "the", "compounds", ...
PMC11463018
C21H19N5O3, [M + H] m/z: 390.15607, found: 390.15605.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "C21H19N5O3", ",", "[", "M", "+", "H", "]", "m/z", ":", ...
PMC8358006
In KYSE450 cells, TF-binding motifs were only enriched (Fisher’s exact test FDR < 0.05) in upregulated genes when using 50,000 background sequence regions as a control.
[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11621493
Next, we performed a crude separation of membrane fractions by sequential centrifugation revealing heavy mitochondrial fractions (HMFs, 3,000 g pellet), light mitochondrial fractions (LMFs, 17,000 g pellet), and microsomal fractions (100,000 g pellet).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6133382
The carbohydrates on purified A244 gp120s produced by CHO-S (A) and MGAT1 CHO (B) cells were released by PNGase F digestion and examined by MALDI-TOF MS as described in the Materials and methods section.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"...
PMC10093184
Strong expression was observed in COS3600B, COS4288, and D-17 cells.
[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "Strong", "expression", "was", "observed", "in", "COS3600B", ",", ...
PMC8740518
In addition, potential survival-related genes were explored by bioinformatics analysis based on the TCGA database.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "addition", ",", "potential", "survival-related", ...
PMC11788920
The quantitative reverse-transcription polymerase chain reaction (RT-qPCR) assay was performed to quantify the endogenous c-Myc messenger RNA (mRNA) level using specific primers and SYBR Green PCR Master Mix kit (Quanta Biosystems) on an Eppendorf Mastercycler RealPlex2 Sequence Detection System.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11323699
Additionally, NACT induced a remarkable 2.9-fold decrease in FOXP3 cells, only within the CD47 group (p = 0.028) (Fig. 3c, right histogram).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11365983
Foxc1 mutation is associated with increased expression of full length Gli3, and its increased processing into the C-terminally truncated repressor form (Gli3R). (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11661024
Analysis was performed by Propidium iodide (PI)/Annexin V-stained cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Analysis", "was", "performed", "by", "Propidium", "iodide", "(PI)/Annexin", "V-stained", "cells", "." ]...
PMC11731614
To our knowledge, this is the first report of these proteins being present as KDEV cargo.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "our", "knowledge", ",", "this", "is",...
PMC11718809
In the ceRNA network, novel_circ_0000023, novel_circ_0000024, novel_circ_0000038, and novel_circ_0000040 all act as sponges, simultaneously sequestering bta-miR-193b and bta-miR-326.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", ...
PMC11791264
The lysates were immunoblotted with the antibodies indicated on the right.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "lysates", "were", "immunoblotted", "with", "the", "antibodies", "indicated", "on", ...
PMC5261804
Both Wnt and androgen signaling have been shown to be important in subsets of ovarian and triple-negative breast cancers [40–42].
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Both", "Wnt"...
PMC9429973
While for elder patients, the outcome makes no difference between two groups, due partly to the poor tolerance in Ibrutinib group.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "While",...
PMC9429973
Results: ALL incidence did not significantly change, however AML incidence significantly increased in women, with estimated annual percentage change (EAPC) of 2.6% during the whole period, and in men since 1998, with EAPC of 3.2%.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11792766
No. A5256701), 100 U/mL penicillin, 100 µg/mL streptomycin, and 2 mM l‐glutamine (Thermo Fisher Scientific, Cat.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "No.", "A5256...
PMC11371747
At physiological pH, l-LV, taken up by RFC, was very effective in protecting cells against antifolates.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "At", "physiological", "pH", ",", ...
PMC9429973
Cyclic GMP-AMP (cGAMP) synthase (cGAS) is a cytosolic DNA sensor that activates innate immune responses through production of the second messenger cGAMP, which activates the adaptor protein STING.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
The CC genotype at the rs6141 and AA genotype at the rs956732 of THPO are risk factors for the ineffectiveness of rhTPO.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "CC", ...
PMC11547972
It might also be worthwhile to explore the interaction of SFN/amygdalin with immune checkpoint inhibitors (ICI) which have been approved for cancer immunotherapy.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10024132
The levels of cytotoxicity achieved by blinatumomab-secreting γ9δ2 T cells were roughly in line with CD19 expression levels.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "levels", "of", "cytotoxicity", ...
PMC11046454
The hallmarks of the TME, including hypoxia, low pH, and elevated levels of adenosine triphosphate (ATP) (Figure S33), have been identified as potential targets for tumor treatments.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
G. Martinelli, A. Santoro, C. Gambacorti-Passerini, S. Vives Polo, S. R. Solomon, S. Mukherjee, E. Lech-Maranda, M. Yair Levy, A. Wierzbowska, M. Calbacho-Robles, G. Marconi, M. Benedetta Giannini, I. Cano, L. Torres Miñana, E. Acuña-Cruz, N. Angelosanto, A. Galleu, S. Baldini, S. Blotta, F. Ravandi, P. Montesinos IRCC...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7812570
A Infection with the replication-competent CCR5-tropic HIV-1 isolates RHPA.c/2635 (subtype B), THRO.c/2626 (subtype B), and MJ4 (subtype C) in TZM-bl cells depends on the presence of DEAE-dextran when the isolates are in the form of cell-free viruses.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", ...
PMC11699465
A CUT&Tag library was constructed using Hyperactive Universal CUT&Tag Assay Kit for Illumina (Vazyme, TD903).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "CUT&Tag", "library", "was", "cons...
PMC11653168
The differential responses between the two cell lines highlight the potential variability in the sensitivity of T-ALL subtypes to Stattic treatment.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "differential", ...
PMC11400680
In this study, we choose SAM as our segmentation model due to two main reasons: (i) its impressive prompt-able segmentation capability and (ii) its zero-short performances.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11585254
Cells were stimulated with 100 nM CXCL13 for 30 minutes at 37°C.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", "were", "stimulated", "with", "100", "nM", "CXCL13", "fo...
PMC11783017
Jiangpeng Wu: Validation, Formal analysis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Jiangpeng", "Wu", ":", "Validation", ",", "Formal", "analysis", "." ] } ]
PMC11240052
Overexpression of hsa_circ_0008285 in cancer cells increased the expression of SIRT-1 and progression of cancer cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Overexpression", "of", "hsa_circ_0008285", "in", "cancer", ...
PMC9429973
To date, DLBCL molecular clusters are identified on the tissue biopsy and do not consider mutations deriving from different anatomical compartments.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "date",...
PMC10818573
Commonly used serological assays utilize techniques such as immunofluorescence staining, enzyme immunoassays, chemiluminescence immunoassays, Western blotting, and immunofluorescence reactions .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Commonl...
PMC11257988
Despite significant clinical advancements in targeted treatments, meeting the clinical demands for KRASG12D mutation remains challenging to date.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Despite", "significant", "clinical", ...
PMC9592219
The sections were blocked with 10% goat serum and incubated overnight with anti-TOP2A (1 : 200, 12286, CST) antibody at 4°C.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11513571
In addition, we examined the effects of rhTSLP on B cell survival and IgG production.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "addition", ",", "we", "examined", "the", "...
PMC8540692
CCM, NaBu, Aza, topotecan, dimethylsulfoxide (DMSO), antibiotics solution (10,000 units penicillin and 10 mg streptomycin/mL), Eagle’s Minimum Essential Medium (EMEM), Dulbecco’s modified Eagle medium (DMEM), fetal bovine serum (FBS), glutamine, nonessential amino acids (NEAA), sodium pyruvate (NaP), ribonuclease A (RN...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7762347
Similar to our results, CYN arrested the cells in G0/G1 phase in HepG2 spheroids and human T-lymphocytes .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O" ], "tokens": [ "Similar", "to", "our", "results", ...
PMC9429973
The median time to initial response was 6.0 weeks (6-12 weeks).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "median", "time", "to", "initial", "response", "was",...
PMC8708099
Our results suggest a possible role for osthole in the protection against inflammation in the gastrointestinal tract; thus, osthole may be considered as an anti-inflammatory modulator.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11767582
The main conclusion was the essential presence of methoxyl or ethoxyl groups at the para position of the B-ring in order to obtain good antitumor activities.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC7642379
In addition, a major loss of copy number of the ADAM3A pseudogene was observed for all cell lines except 293-H with a maintained low or no expression of the pseudogene observed in the cell lines (Fig. 2a,b and Supplementary Fig. S4).Figure 2Copy number variation analysis of HEK293 progeny cells compared to the parental...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", ...
PMC10932641
The siGPRC5D-AS1 group was created as follows: for preparation of the siGPRC5D-AS1 diluent, 5 µL of siGPRC5D-AS1 was diluted with 120 µL Opti-MEM and mixed gently; for preparation of Lipofectamine diluent, 5 µL of Lipofectamine 2000 was diluted with 120 µL of Opti-MEM, mixed gently, and placed for 5 min at room tempera...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11637284
P, pellet; SN, supernatant; FT, flow through; IP, eluate of immunoprecipitation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "P", ",", "pellet", ";", "SN", ",...
PMC9031474
The results by Kitte and Tretbar et al. suggest that a terminal double bond at the C4 position of muzigadial (26) increases its cytotoxicity.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9429973
Aims: This study aims to quantify the healthcare resource utilization (HRU) and costs, during and post-completion of therapy, with venetoclax plus obinutuzumab (VO) or venetoclax plus rituximab (VR).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11604768
Libraries prepared from RNA samples were pooled at equimolar concentrations and combined with plasmid DNA input amplicons such that plasmid amplicons represented approximately 6−8% of the pool.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10993311
Furthermore, we did not perform DNAm validation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Furthermore", ",", "we", "did", "not", "perform", "DNAm", "validation", "." ] } ]
PMC9688728
A similar conclusion was drawn about the decreased value of KEGG match status.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "similar", "conclusion", "was", "drawn", "about", "the", "decreased", ...
PMC9429973
Methods: We used ball sedimentation assay (BS) and elastic motion thromboelastography (ClotPro) to monitor the lysis of fibrin containing plasminogen and tissue-type plasminogen activator (tPA) at various RBC-counts and TXA concentrations.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6600253
This suggest that stilbene compounds have the potential to induce senescence through the inhibition of telomerase activity in cancer cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "suggest", "that", ...
PMC9429973
LOT was algorithmically defined based on drug regimen, time since administration, and gap between regimens.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "LOT", "was", "algorithmically", "defined", "based...
PMC11472569
Zhao et al. revealed that CAF-derived exosomes transport essential nutrients to cancer cells and modulate cancer cell metabolism.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Zhao", "et", "al.", "revealed", "that"...
PMC10291556
Extracellular level of HMGB1.
[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "Extracellular", "level", "of", "HMGB1", "." ] } ]
PMC10840195
According to the GEPIA database (http://gepia.cancer-pku.cn/), patients with high Twist expression had obviously shorter progression-free survival (PFS) and overall survival (OS) times than those with low Twist expression (Fig. 3C, D).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6600592
C NMR (CDCl3) δ 171.90 (C-10), 155.87 (C-7), 135.19 (C-4), 133.71 (C-1), 128.70 (C-2, 6), 127.61 (C-3, 5), 72.99 (C-14), 62.13 (C-21), 31.57 (C-15, 19), 31.10 (C-9), 25.35 (C-8), 23.72 (C-17), 22.16 (C-16, 18).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11665584
The buccal mucosa had significantly fewer immune cells compared with control skin while PITX1 skin had a nonsignificant increase (Figure 1C and Figure 4B).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC7602170
Therefore, more research will have to pay attention to the potential of those inhibitors of PI3K (BKM120, BYL719, GDC-0941), AKT (Perifosine), mTOR (RAD001) and Dual PI3K/mTOR (BEZ2335, GDC-0980), combined with imatinib.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10204952
Further mouse xenograft study is warranted to confirm whether adipocytes could impose a significant impact on the anti-proliferative effect of S1P against breast cancer cells at high concentrations (high nM to low μM).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
In the chronic lymphocytic leukemia and multiple myeloma group in-hospital mortality was 27% and 17% respectively, and in 100% cases deaths were caused by severe coronavirus disease.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11478724
Decreased VDAC1 expression can suppress cell energy and metabolism.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Decreased", "VDAC1", "expression", "can", "suppress", "cell", "energy", "and", "metabolism", "." ] } ...
PMC11442172
Especially with the integration of primary, PDTO cultures, a superior reproduction of the in vivo conditions could be obtained.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Especially", "with", ...
PMC9429973
An IND application in DLBCL has been completed with initiation of first in human clinical trials planned in 2022.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "An", "IND", "application", "in", ...
PMC9429973
Subsequent treatments beginning in or after Jan 2016 were included to focus on contemporary therapies.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Subsequent", "treatments", "beginning", "in", "or", "after", ...
PMC11471176
Initially, near normal-like cancer cells downregulate ACE2 in an effort to control proliferation where ACE2 seems to act as a balancing enzyme.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Initial...
PMC11092382
The aforementioned traditional Chinese medicine formulas, which contain sophocarpine as the primary active ingredient, have exhibited diverse therapeutic effects (Table 3).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973
Similarly, CSN5/Jab1 gene silencing resulted in decreased cell growth associated with increased expression of similar cell cycle inhibiting proteins.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Similarly", ",", "CSN5/Jab1"...
PMC10329074
ns: no significance.
[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "ns", ":", "no", "significance", "." ] } ]
PMC10440586
Glioma cells are divided into four cell states: OPC-like, NPC-like, MES-like, and AC-like. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Glioma", "cells", "are", "divided", "i...
PMC10523483
Furthermore, upon ionizing radiation, which damages DNA while producing excessive ROS, H1.2 is disassociated from chromatin to facilitate DNA damage repair (30), this suggests that H1.2 may dynamically respond to ROS stimuli, but whether it participates in antioxidant defense remains unknown.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5308810
After three cell passages, the isolated CXCR4 population lost its purity (with 68% of the cells underwent CXCR4High⇒Low transition).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After",...
PMC9429973
In the responders, the median time to first response was 1.07 months (range: 0.25-2.71), and the median duration of response (DOR) was 7.75 months (95% CI: 4.705-10.795).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Discontinuations due to AEs generally occurred early into treatment, with low rates of discontinuation due to gastrointestinal, liver, effusion and renal AEs.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC6222635
In recent decades, scientists have found that the polysaccharides in this plant exhibit fine bio-activities, including anti-tumor, immunomodulatory, hypoglycemic, anti-inflammatory, and antioxidant activities.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11754784
Finally, cells were washed with DPBS three times and analyzed by flow cytometry.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Finally", ",", "cells", "were", "washed", "with", "DPBS", "three...
PMC11529598
Knockdown of miR-3154 upregulated TP53INP1 at both mRNA and protein level.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Knockdown", "of", "miR-3154", "upregulated", "TP53INP1", "at", "both", "mRNA", "and", ...
PMC8010066
Moreover, antibiotic susceptibility increased more efficiently in the planktonic form comparing to the biofilm one.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "antibiotic", "susceptibility", "increased",...
PMC11267830
Protein samples were frozen with liquid nitrogen, ground, and mixed with lysis buffer.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Protein", "samples", "were", "frozen", "with", "liquid", "n...
PMC11525028
Combination of paliperidone and AG-401 inhibited osteosarcoma progression in organoid and PDX models (A) Diagram depicting the workflow of drug synergy assay and establishment of PDX models and organoids. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11012012
Therefore, SLAMF receptor-mediated inhibition of macrophage phagocytosis is critical to hematopoietic homeostasis, and SLAMF receptors may represent previously unknown targets for tumor immunotherapy .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9221284
The five transcripts were correlated with the production of c-Myc2 and c-MycS, and loss of c-Myc1.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "five", "transcripts", "were", "correlated"...
PMC11721587
The distribution of Fu in condensates (P100) and supernatant (S100) at different time points after incubation was analyzed by immunoblot after re-centrifugation. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...