Datasets:
OTAR3088
/
BioData-CellLine_annotated

Dataset card Data Studio Files
xet
 Community
1
PMCID
string
Sentences
string
ner
list
PMC11394112
Next, we confirmed U2932-Luc and VAL-Luc infiltrations into the initially targeted organs and spleen, liver, and lung tissues by immunohistochemistry (IHC) staining for the human CD20 B cell surface marker.
[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7171147
N = 3.
[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "N", "=", "3", "." ] } ]
PMC11673128
All cell lines were not independently authenticated beyond the identity provided by the institution of origin and were routinely tested for mycoplasma contamination.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", ...
PMC11737091
Inhibition of DDK has been shown to induce tumor-specific cell death without compromising the viability of nontransformed cells, highlighting its significant value in cancer treatment strategies .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11451940
Then, the methanolic solution of the deprotonated Lap was added dropwise, and the mixture was allowed to react for 3 hours.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Then", ...
PMC9143157
Doxil was purchased from Janssen Pharmaceutical K.K. (Tokyo, Japan).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Doxil", "was", "purchased", "from", "Janssen", "Pharmaceutical", "K.K.", "(", "T...
PMC11600602
Keratinocytes originating from the somatic ectoderm, exactly like those of the epidermis, build up the epithelial lining of a series of juxta-cutaneous mucous membranes (oral and nasal cavities, eye surfaces, external genitalia, distal anus) as well as the tissue framework of extra-cutaneous organs, such as the thymus.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10530622
PH is estimated to account for 1–2% of pediatric cases of End-Stage Renal Disease (ESRD), a condition that requires dialysis or organ transplantation in order to children to survive .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9318744
In a similar strategy, they predicted that the inner shell disorder of the omicron is inherently attenuated, like pangolin-CoV 2017, an attenuated precursor of SARS-CoV-2 that might have jumped from pangolins to humans in 2017.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Gr 3–4 thrombocytopenias and infections were not reported, as were any Gr infusion-related reactions (Table).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Gr", "3–4", "thrombocytopenias", "and", ...
PMC11725127
In vitro deubiquitination assay.
[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "In", "vitro", "deubiquitination", "assay", "." ] } ]
PMC11765678
These findings were also confirmed in a BCRP-expressing human breast cancer cell line (MCF-7/MXR), which was selected for resistance to Mitoxantrone.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "I-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11599565
This neuronal or epithelial signature of ovarian carcinomas is raised from a rare cell type found in regular (non-tumoral) ovarian tissues which have a particular phenotype expressing Tyrosine hydroxylase, ChgA, the paraneoplastic protein PNMA1 and KRT80.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11758416
Set up 96-well round bottom plate for cytotoxicity assay by planning locations for conditions and labeling.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Set", "up", "96-well", "round", "bottom", "plate", ...
PMC9621239
n = 3; Original magnification, ×400.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "n", "=", "3", ";", "Original", "magnification", ",", "×400", "." ] } ]
PMC9712534
Site-directed mutagenesis of the EGFP-TOP2B expression plasmid was performed using specific oligonucleotides to yield H58Y, T65I, Y66F, G180I, and L185F substitutions.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11739484
The AUC values exceeding 0.8 indicate high accuracy in discriminating between the two groups, underscoring the efficacy of these MMPs as novel biomarkers for early detection of SKCM.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11785489
This TCR property, referred to as “generic MHC reactivity,” has been theorized based on thymic development in TCR-transgenic mice.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", ...
PMC9429973
The most common β-globin mutations were IVS1-nt110 G>A (63.7%), Codon 39 C>T (25.4%), and IVS1-nt6 T>C (22.9%).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11045125
LMP1 expression can be reactivated (in the absence of concomitant EBNA2 expression) in EBV+ BL cell lines by treatment with IL21, an effect potentially mediated by STAT3 activation [34–36].
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11718109
For all imaging, cells were seeded on glass-bottom matTek dishes (MatTek corporation).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "all", "imaging", ",", "cells", "were", "seeded", ...
PMC9841531
Cell viability was determined as described before by adding 20 μL of a 5 mg/mL solution of MTT to each well and further incubation for 1 h. Eventually, the supernatant was removed and 100 μL of DMSO was added to each well.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Furthermore, physicians need to gain confidence in understanding and managing associated adverse events (AEs) to optimize patient risk-benefit and individualize therapy.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9587298
The decrease in MGO-induced HepG2 cells toxicity can be attributed to the ability of elderberry extracts to trap MGO, an effect mainly attributed to cyanidin-3-glucoside and cyanidin-3-sambubioside, but also to cellular metabolism.
[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11012012
Individual SLAMF receptors are expressed on the surface of hematopoietic stem cells, hematopoietic progenitor cells, B cells, T cells, NK cells, NKT cells, monocytes, macrophages, dendritic cells, neutrophils, and platelets.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11387401
Differential expression on normalized counts was assessed using the DESeq2 package (1.30.0) in R (64 Bit, version 4.0.3) by comparing HIV-1 protein nRIPseq samples simulaneously with the corresponding anti-mouse IgG and GFP background controls.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Data were obtained on the occurrence or not of acute COVID-19 -associated VTE, the site of thrombosis, ongoing anticoagulant treatments, and the results of laboratory tests performed at the first post-discharge assessment visit, including blood cell count, D-dimer, fibrinogen, CRP and LDH.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6182045
bNAbs against HIV often contain unusual characteristics such as high levels of somatic hypermutation or long complementarity domain regions that are difficult to elicit in animal models (4, 29, 30, 44, 45).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11052306
Thus, there is a very good safety index for the gold complex, but only for EPC cells .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thus", ",", "there", "is", ...
PMC11676670
This rarity makes the OVAR79 line particularly valuable for exploring the functions of p53 and its downstream regulatory pathways, including its roles in DNA repair, apoptosis, and cell cycle control.
[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10759659
In addition, ARID1A deficiency was associated with a higher TMB, more infiltrating lymphocytes, and increased PD-L1 expression in various tumours .Moreover, mice with ARID1A-deficient ovarian cancers showed a prolonged survival rate when treated with ICBs .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7039683
Histogram of read density of ATAC-seq in 10 kb flanking transcription start sites (TSS). (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Histogram", "of", "read", "density", "of", ...
PMC11138140
We first analyzed the surface area dynamics of both the untreated and norepinephrine-stimulated cardiomyocytes over the 24 h imaging period (Figure 2C).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11021472
Effective overexpression of circZDHHC11 was obtained in ST486 upon infection with a lentiviral vector containing the circZDHH11 sequence.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Effective", "overexpression", "of", "circZDH...
PMC9429973
Aims: To evaluate the impact of doxycycline use for post-ASCT antimicrobial prophylaxis on survival in AL amyloidosis patients.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ":", "To", "evaluate", ...
PMC4816271
In anticipation of this eventuality, we co-expressed CAR with the iCasp9 suicide gene and optimized a bi-cistronic retroviral cassette to maintain co-expression and consistent transgene output.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11536589
These results indicated that PKF-118-310 combination with MRTX1133 synergistically sensitize MRTX1133-resistant PDAC cells to MRTX1133 and reverse MRTX1133 resistance by inducing ferroptosis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC10674574
The cytotoxicity of compounds on the Caco-2 monolayer is one of the crucial limitations of permeability assessments in in vitro conditions.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cytotox...
PMC11683240
α1AT, α1-antitrypsin.
[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "α1AT", ",", "α1-antitrypsin", "." ] } ]
PMC9429973
Approximately 20% of patients with MF evolve to a HR MF with transformed cells (tMF), which is associated with a poor prognosis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11574029
Immunohistochemistry (IHC) was performed to evaluate the expression of NOTCH3 and SPP1 proteins in BLCA patient tissues, as described in previous studies .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC3995603
The absorbance was measured at 450 nm using a microplate reader (BenchmarkPlus, Bio-Rad Laboratories Inc., U.S.A.) and the percentages of viable cells were calculated.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
This data confirms the importance of proteasome inhibitors in HR RRMM.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "data", "confirms", "the", "importance", "of", "proteasome", "inhibitors", "in", ...
PMC11285179
Overexpression and knockout of CCL28 in human lung adenocarcinoma cell line A549 and murine lung adenocarcinoma cell line LLC, respectively, were utilized to establish mouse models.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "I-CellLine", "B-CellLine", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", ...
PMC11657695
All cell lines were subjected to a complete validation process and were authenticated by Short Tandem Repeat (STR) profiling analysis (Eurofins, Germany).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11615101
The bar graph shows the fluorescence intensity of TLR-4 expression in RAFLS after the knockdown of α-Taxilin compared to the α-Taxilin and NS group. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9504875
Anti-FLAG mAb and polyclonal Ab (pAb) were obtained from Sigma (St. Louis, MO, USA), anti-myc mAb from MBL (Nagoya, Japan).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11352746
Such systems may be useful in specific circumstances to study the modulation of specific targets/target pathways if appropriate controls, benchmarks, and orthogonal assays are employed.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11769522
CPEKs incubated with 30, 60, or 90 ng/mL of IFN-γ showed significantly increased CCL2 concentrations in their culture medium compared to those treated with 10 ng/mL of IFN-γ (Figure 2D).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11774747
Rossig et al., demonstrated that stimulation through the CAR alone was not sufficient to maintain proliferation and expansion of CAR-VST beyond four weeks (81).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Preclinical studies suggest overexpression of anti-apoptotic MCL-1 as a mechanism of BCL-2 inhibitor resistance (Konopleva et al. Cancer Cell 2006).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Preclinical", ...
PMC11402217
High DKK1 expression correlates with worsened malignancy and prognosis in OS, but its over-suppression could inadvertently trigger oncogenic Wnt/β-catenin signaling.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "High", "DKK1", "e...
PMC11411004
P < 0.01 vs. NC Small-molecule epigenetic modulators are used to treat a wide range of human pathologies by targeting specific proteins and pathways that affect cellular function (Zhang et al. 2021) and are therefore highly relevant for drug discovery and disease treatment (Singh et al. 2018).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11506827
Therefore, for further investigations, A498 cells were pre-treated with 200 μg/mL GEF for 12 h, followed by treatment with 10 ng/mL TRAIL for another 12 h. The morphologies of both 786-O and A498 cells were altered after 12 h of pre-treatment with GEF, followed by a TRAIL treatment for another 12 h, whereas no signific...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11790971
The impurity score is defined as:6[12pt] $$_}=1-_}}_}}$$=1−NcorrectNtotalwhere is the total number of cells in the test set, and is the number of cells of which the predicted cell line class is included in its annotated candidate class(es).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
The estimated DOR and PFS rates at 12 months were 64% and 56%, respectively.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "estimated", "DOR", "and", "PFS", "ra...
PMC11467964
From 223 BMRGs, we screened out BMRGs were differentially expressed between STS and normal tissues.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "From", "223", "BMRGs", ",", "we", "screened", "o...
PMC10968586
Treatment of PC-3 cells with 30 μM and 100 μM HT for 24 h reduced the migration rate in a dose-dependent manner.
[ { "tags": [ "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Treatment...
PMC6114978
Anti-YAP (D8H1X XP; catalog #14074) utilized for Western blot was obtained from Cell Signaling (Danvers, MA, USA).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973
Raman spectra serve as ‘molecular fingerprints’ characterizing biochemical composition of complex cellular structures.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Raman", "spectra", "serve", "as", "‘", "molecular", "finger...
PMC11726183
Nearly 50 significant parameters can be obtained from the QikProp module.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Nearly", "50", "significant", "parameters", "can", "be", "obtained", "from", "the", "...
PMC4443654
Each model, trained in one cell type, was applied to the chromatin feature datasets from the other two cell types. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Each", ...
PMC11345828
In a humanized Mcl-1 mouse model, Mcl-1 inhibitor S63845, structurally related to compound 1, was found to have a ∼3-fold lower maximum tolerated dose than in wild-type mice, but the changes observed in hemopoietic cells were transient and no organ damage was observed.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7723249
Caco-2 is a human epithelial cell line, which becomes polarized when grown on permeable membranes.
[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Caco-2", "is", "a", "human", "epithelial", "c...
PMC11490153
The presence of other bands in EO and AlgNPs demonstrated the successful loading of EO in the prepared AlgNPs.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "presence", "of", "other", ...
PMC9219615
Thienopyrazoles derivatives have well-documented anticancer activity, yet this class of compounds has been mostly ignored.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thienopyrazoles", "derivatives", "have", "well-documented", ...
PMC8658661
A similar pattern was found in the case of insulin-like growth factor 2 (IGF2) , which is associated with the development of various diseases in children—for example, Beckwith–Wiedemann syndrome .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10810426
NIH3T3 cells were grown in 0.2% or 10% serum, infected with MLV (MOI = 1) and infection levels were measured at the indicated times.
[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11758416
CFSE toxicity: CFSE may be toxic to the L cells resulting in dead or dying target cells prior to incubation with effector cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11612626
Assays were performed in triplicate.
[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Assays", "were", "performed", "in", "triplicate", "." ] } ]
PMC9429973
Both doses of vaccine were well tolerated in all pts.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Both", "doses", "of", "vaccine", "were", "well", "tolerated", "in", "all", "pts", "." ...
PMC11774112
The percentages of apoptotic cells in the DTIC, miRNA 34a, DTIC + miRNA 34a, PHRD-DTIC, PHRD-miRNA 34a and Co-PHRD groups were 12.07%, 5.23%, 40.82%, 28.3%, 19.63% and 60.25%, respectively (Figure 4E).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11206502
To determine OCR and ECAR significance between baseline and stressed conditions for every treatment, a Mann–Whitney test for independent samples was applied.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11457557
The MYH9 (myosin, heavy chain 9)/APOL1 (apolipoprotein L1) locus was associated with T2DM in African Americans, according to results from another high-density GWAS, and these results were replicated in a study of candidate gene and in a familial linkage analysis .The MYH9/APOL1 function in DKD is fast growing and remai...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8973725
ZNF471 suppresses cervical cancer cell invasion by modulating EMT via negative regulation of the Wnt/β-catenin signaling pathway .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ZNF471", "suppresses", "cervical", "cancer", "cel...
PMC9429973
Furthermore, the PTPN11 mutation and a high RDW level may involve a synergy during the natural course of JMML.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Furthermore", ",", "the", ...
PMC11269792
Furthermore, due to the high stability and conservation of circRNAs and their high abundance in body fluids, circRNAs have been considered potential biomarkers for GIST.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11656048
As expected, overexpression of Nrf2 partially reversed the downregulation of xCT and GPX4 protein expression in MG63 and 143B cells induced by shikonin (1.5 uM) (Figures 5C, D).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "...
PMC11394386
The mechanism involves a feedback loop wherein HIF1α induces HOTAIR overexpression, which in turn sustains transcriptional activity in the Wnt/β-catenin pathway and possibly enables continued PI3K/AKT pathway activation by methylating the PTEN promoter.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10607604
RNA quality was checked by assessing the ratio between the absorbance values at 260 and 280 nm.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "RNA", "quality", "was", "checked", "by", "a...
PMC11564322
In each experiment, the treatment was repeated six times in the experimental group In our experiments, after the 24-h exposure of the HL-60, K562, and MEG-A2 cell lines to the VGVAPG and VVGPGA peptides, only the VGVAPG peptide significantly increased the KI67 mRNA expression (by 55.02%) compared to the control (Fig. 2...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", ...
PMC11155445
Complex 72c showed pseudo-tetrahedral piano stool geometry consisting of Ru ions, chlorido ions and bipodal acyl thiourea ligand.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Complex", "72c", "showed", "pseud...
PMC9429973
Microcytosis evaluated by mean corpuscular volume was more marked in the family carrying the 105 bp (57.8 fL) deletion, while the single base deletion resulted in a MCV of 65.8 fL. About to the mean corpuscular hemoglobin levels to determine hypochromia, the values furthest from the normal are observed to coincide with...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10291556
The proton resonances in the H spectra for enDCF are shifted downfield when compared to that of DCF, as shown in Figure S3.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11695623
The differences of DCUN1D5 expression between lung adenocarcinoma and normal tissues were compared by TCGA, GEO and UALCAN databases, and the relationship between DCUN1D5 expression and clinicopathological features of patients was analyzed.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10605143
Importantly, HSF1 was shown to interact with MTA1 , a component of the NuRD complex that, in cooperation with SNAI1, represses CDH1 expression .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC10158546
Number of spheroids per image. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Number", "of", "spheroids", "per", "image", ".", "(" ] } ]
PMC11001582
As polyPR is less abundant than polyGR in human postmortem tissue, our polyPR mice, while still expressing at relatively low levels, are likely to express polyPR at higher levels than that observed in patients.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11506670
For each setup, a linear graph illustrating the percentage of the open wound area over time was generated, and the slope of each line equation was calculated to determine the rate of wound closure.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7229095
Low cell density condition itself is reported to have hindered growth rate (Ozturk and Palsson 1990) due to the decrease in secreted growth factors from the inoculated cells (Lim et al. 2013).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11502066
Anticancer effects of flavonoids mediated by GPCRs.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Anticancer", "effects", "of", "flavonoids", "mediated", "by", "GPCRs", "." ] } ]
PMC11748335
The top 20 LOLA terms that exhibited the most significant enrichment for peaks in short LOCKs were displayed (Fig. 5B).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "top",...
PMC10705095
These findings indicate that while hemoglobin primarily functions as an oxygen carrier in erythrocytes, emerging evidence suggests that it may also play diverse roles in cancer development and progression.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11594074
This was followed by an equilibration phase, first under an NVT ensemble for 100 ps at 300 K and then under an NPT ensemble for 200 ps at 300 K and 1 atm pressure.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11261875
In the context of GIST, it has been demonstrated that elevated GLUT-1 expression corresponds to an increased tumor risk grade .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "the", "cont...
PMC4659567
In particular, complex containing lonidamine-modified imidazole ligand exhibited IC50 values of 19.3, 17.9, 6.4, 8.3, 5.7, 20.5 and 20.2 μM against human cisplatin-sensitive (A2780) and -resistant (A2780R) ovarian cancer cell lines, human glioblastoma cell lines LN18, LN229, LNZ308, non-cancerous HEK cell line, and cor...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11087055
For quantitatively analyzing the cell flow pattern, the recorded images were further processed by using Particle Image Velocimetry (PIV) and subsequent visualization techniques.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC3274243
Oncoprobe cultures were monitored for 18 h. Chamber slides containing treated and untreated control cells were fixed with 70% ethanol after 18 h, air-dried and stained with Harris’ Haematoxylin (Sigma, Poole, UK).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC2614416
Sierra-Rivera and co-workers noted that the decline in enzymatic activities of CuZnSOD, MnSOD and catalase in hepatoma was due to a decline in the levels of immunoreactive proteins.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11534035
Similarly, GPER1 activation via the agonist G1, also exerts a repressive effect on proliferation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Similarly", ",", "GPER1", "activation", "via", "the", ...