OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC10914904	The stem-loop structure in the apical region of vtRNA 1-1 enhances resistance to apoptosis by modulating the PI3K/Akt and ERK1/2 MAPK signaling pathways, with critical nucleotides for apoptosis resistance encircled in blue .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11621565	As previously stated, the discovery that PD pathological changes appear in the gastrointestinal tract has brought the gut microbiota into focus.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "As", "previo...
PMC11705862	Similar glucolipotoxic conditions also caused downregulation of IRIS-1 and 2 in pancreatic β-cells, where they are involved in insulin granule exocytosis .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Similar", "g...
PMC11643361	This review addresses recent findings on scorpionate complexes, emphasizing the impact of metal choice and ligand design on biological activity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "review", ...
PMC9429973	Most common AEs (n=38) were CRS (63%; all grade 1/2; median time to CRS onset: 3 d [range, 2–6], duration of CRS: 2 d [range, 1–4]), thrombocytopenia (42%; grade 3/4, 29%), neutropenia (55%; grade 3/4, 50%), lymphopenia (40%; grade 3/4, 37%), and anemia (39%; grade 3/4 29%), Grade 3 ICANS was reported in 1 pt which res...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10998613	Although the role of CXCR4 in cancer is widely reported, it is intriguing to find that it interacts with β2AR, an important protein in stress response.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11317131	PE insertion of att sites ranged from 0.3% to 62.1% as measured by amplicon sequencing using genomic primers flanking the insert (Figure 1B) and confirmed by droplet digital PCR (ddPCR), a form of quantitative PCR that reports highly accurate copy number of genomic inserts over a wide range of template concentrations (...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8662250	These observations had also been confirmed by a marked release of proinflammatory cytokines IL‐6, TNF‐α, each well‐known downstream product of TLR‐4 activation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11740207	Their ability to exhibit pluripotency similar to iPSCs suggests that they have a higher proliferative potential than PGCs, supporting the hypothesis that VSELSCs originate from EpibCs through AD.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11799978	Two 10 cm Petri dishes were prepared, and CAFs cells were placed in cell culture dishes at a density of 3 × 10 cells per plate.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11723947	Data acquisition was performed on Symphony A5 (BD Biosciences) and analyses were carried out using FlowJo software.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "acquisition", "was", "per...
PMC2614415	Analysis was performed as described in Figure 3.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Analysis", "was", "performed", "as", "described", "in", "Figure", "3", "." ] } ]
PMC11407042	Shake the dish gently to ensure the even distribution of cells.g.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Shake", "the", "dish", "gently", "to", "ensure", "the", "even", "distribution", "of",...
PMC9878562	Deletion of blt1r was confirmed by genomic sequencing of the locus.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Deletion", "of", "blt1r", "was", "confirmed", "by", "genomic", "sequencing", "of", "t...
PMC11612508	The biopharmaceutical characteristics of microspheres, their biodistribution, and the absorption of microsphere content can all be influenced by size.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "biopharmaceutica...
PMC7823217	Schematic diagram of a two-step 3D bioprinting method in which hiPSC-HPCs were patterned by the first digital mask followed by the patterning of supporting cells using a second digital mask.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11448304	g Subcellular localization of significantly regulated proteins Furthermore, the Motif-X tool was utilized to extract overrepresented patterns of Khib modification sites .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "g", "Subcell...
PMC10530622	A classic example is the triad of primary hyperoxaluria, nephrolithiasis, and kidney injury.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "classic", "example", "is", "the", "triad", "of", ...
PMC11659734	Given the rising production of BPA alternatives, developed to replace BPA due to its concerned effects on human health, and the incomplete toxicological profiles of these compounds, there is an urgent need for comprehensive studies to assess their potential risks.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11706491	The cell cycle reporter strain was constructed in the following way: Sid2-GFP strain was obtained from elsewhere .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cell", "cycle", "reporter", "st...
PMC11588085	All experiments have been performed at least 3 times.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "experiments", "have", "been", "performed", "at", "least", "3", "times", "." ] } ]
PMC11519567	G Representative image of BJ fibroblasts expressing SS18-SSX1-EGFP when treated with 3% or 20% 1.6-hex.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "G", "Representative", "image", "of", "BJ", ...
PMC11144382	Moreover, short-term treatment of murine primary calvarial osteoblasts with RA induced an increase in Crabp2 expression and other genes involved in retinol-dependent signaling and skeletal remodeling.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8992508	The TMD instead crosses the membrane and is composed of a number of transmembrane sequences, putative alfa-helices, separated by hydrophilic loops.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...
PMC9780037	After its translation, cyt c is extensively imported into mitochondria.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "its", "translation", ",", "cyt", "c", "is", "extensively", "imported", "into...
PMC11792766	Methanol, acetone, and acetonitrile did not present a notable decrease in the viability of the two aforementioned cell lines at 0.5% v/v concentration, whereas DMF and DMSO presented a borderline non‐statistically significant reduction (p‐value slightly above 0.05) in the viability of HepG2 and Caco‐2 cell lines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3019555	HeLa–GFP-Ago2 cells were incubated in glucose-free media for 1 h and stained for α-tubulin (white).	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "HeLa", "–", "GFP-Ago2", ...
PMC11759751	By the 12th day, transduction efficiency was assessed using flow cytometry to determine the percentage of CAR-T 19 cells within the CD3+ T cell population.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11697703	During neural development, MapK8 controls multiple processes including cell death, proliferation, soma size, migration, and dendritic arborization.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "During", "ne...
PMC11802855	In both H929 and RPMI 8226 cell lines, the levels of p-JAK1 and p-STAT3 were significantly increased in CXCL7-OE group (Fig. 6E).	[ { "tags": [ "O", "O", "B-CellLine", "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O"...
PMC10495912	Cell membrane integrity As shown in Figure 4-D, no significant changes were observed following the exposure of HepG2 cells to different doses of TQ and hydrogen peroxide alone.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", ...
PMC7053076	The most potent analog of the series, (R)-3-(4-bromophenyl)-1-ethyl-5-methylidene-6-phenyldihydrouracil, designated U-332 (Fig. 1), caused in HL-60 cells excessive DNA damage which led to the cell cycle arrest in G2/M phase and apoptosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", ...
PMC11687663	It involves simulating the interaction between the two molecules to predict the most energetically favorable binding pose .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "involves", "simulating", "the", "interactio...
PMC10926885	In order to fill the research gap pertaining to the impact of NDE1 on the genesis and progression of cancer, our study also included experimental investigations aimed at elucidating the role of NDE1 in facilitating the proliferation, migration and invasion of bladder cancer cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11047729	It lowers the expression of hTERT and c-myc mRNA through protein kinase C inhibition .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "lowers", "the", "expression", "of", "hTERT", "and", "c-myc...
PMC11766332	Notably, the study identified ASD-miRNA targets that include glycogenes, whose detrimental mutations are linked to congenital disorders of glycosylation—metabolic conditions with significant neurological involvement, including ASD.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11750712	At the highest dose level (450 × 10 CAR T cells), all four patients achieved an objective response with three patients achieving CMR and one patient achieving a PR by PET-CT.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Response rates with the combination were encouraging in frontline and salvage, with favorable OS.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Response", "rates", "with", "the", "combination", "were", "...
PMC9878562	The expression of enzymes involved in LTB4 production suggested that CXCL12 and LTB4 could act synergistically in stimulating VAL-wt migration through a positive feedback loop.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11686380	Scale bar, 50 μm. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bar", ",", "50", "μm", ".", "(" ] } ]
PMC10993311	Likewise, the significant biological covariates identified by SVD analysis showed slightly different patterns in each group, indicating that hs-CRP in T3, length In T3, and FL in T3 may be related to the epigenetic signature.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10654497	Therefore, lung cancer is often associated with resistance to a variety of targeted treatments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "lung", "cancer", "is", "often", "associat...
PMC9429973	Effectiveness endpoints were change from baseline (CFB) to 48 weeks in hemoglobin (Hb), red blood cell (RBC) transfusions, lactate dehydrogenase (LDH), absolute reticulocyte count (ARC), and % PNH RBCs relative to PNH white blood cells (WBC).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11592837	Since DOX-treated PBMCs displayed no elevated cell death and a markedly decreased n-cfDNA integrity index at later time points, we speculate whether a protective cellular response to DOX potentially reduced cytotoxity until 8 h. In drug-treated Jurkat cells, higher cell death-specific γH2AX staining, increased mt-cfDNA...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9504875	This study elucidated new strategies for how nairoviruses evade host IFN systems.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "study", "elucidated", "new", "strategies", "for", "how", "nairoviruses", ...
PMC5034105	None of the mouse, rat and bat cell lines showed a ⩾2 log increase in viral load within 5 d.p.i.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "None", "of", "the...
PMC11772585	HSC-1 and A431 cells were seeded in 6-well plates and cultured for 24 min.	[ { "tags": [ "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "HSC-1", "and", "A431", "cells", "were", "seeded", "i...
PMC4443654	Finally we used model predictions to examine boundary composition between higher-order domains across cell types.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Finally", "we", "used", "model", "predictions", "to", "exam...
PMC11026382	The standard error in growth rate was computed across triplicate measurements.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "standard", "error", "in", "growth", "rate", "was", "computed", "across", "trip...
PMC11680391	We retrieved information from the National Danish Cattle Database.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "retrieved", "information", "from", "the", "National", "Danish", "Cattle", "Database", "." ] } ]
PMC10589262	A Activation status of the three arms of the unfolded protein response (UPR) pathway (ATF6, IRE1α, and PERK) was measured by western blotting in a panel of cancer cell lines expressing WT-KIT or MT-KIT.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Other dynamic states patients could enter and leave during follow-up were treatment & no transfusion, transfusion & no treatment and no treatment & no transfusion (considered as TTT-free survival).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10582049	Projection of samples isolated from indolent and aggressive LUADs within stromal cell subpopulation (right). (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Projection", "of", "samples", "isolated", "from",...
PMC11486946	The preparation process for EGFR-transfected Ba/F3 cells was almost the same as that for other cells, except that floating cells in Eppendorf tubes were centrifuged with 800 × g for 2 min to replace the supernatant after every step.	[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11753435	For immunocytochemistry, the cells were gently shaken in blocking buffer [5% (v/v) normal goat serum (Jackson ImmunoResearch) and 0.2% (v/v) Triton X-100 in 1× PBS] at RT for 1 hour, followed by overnight incubation in the blocking buffer with primary antibodies at 4°C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11190238	Fig. 2Hierarchical order of the 3D genome.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fig.", "2Hierarchical", "order", "of", "the", "3D", "genome", "." ] } ]
PMC11365983	Fig. 4Foxc1 alters the dynamics of Hh signaling and enhances Gli2 accumulation at the ciliary tip. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fig.", "4Foxc1", "alters", "the", "dynamics", ...
PMC10093184	COS3600B and COS4288 cells produced visible colonies after anchorage-independent growth in soft agar.	[ { "tags": [ "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "COS3600B", "and", "COS4288", "cells", "produced", "visible", "c...
PMC9429973	Thrombocytopenia is defined by platelet level lower than 150,000/uL. Incidences of thrombocytopenia and related complications were recorded and analyzed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thrombocytopenia", "is", "defined", ...
PMC10761571	As was observed in this work, treating lung adenocarcinoma cells with Fe3O4@Glu-Gingerol led to upregulation of the CASP8 and BAX genes, while it down-regulated the BCL2 gene.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The combination of azacitidine with bexmarilimab augmented HLA-DR induction by 20-110% (mean 44%).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "combination", "of", "azaci...
PMC3122064	Moreover, treatment with RITA induced caspase-dependent apoptosis in NCCIT, the TC cell line expressing mutant p53 (Supplementary Figure 2a), indicating that at least in TC cells RITA induces apoptosis independent of wild-type p53.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8633974	Our data establish an association between tat/rev target DNA conservation and CRISPR-Cas9 efficacy across multiple HIV-1 transmitted founder strains (Figure 2b).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Our", ...
PMC9429973	Univariate and multivariate logistic analysis of potential influencing factors for CR rate showed that CD200 was an independent influencing factor for CR rate after the first course of chemotherapy, and the probability of obtaining CR in the CD200 negative group was 4.15 times that of the CD200 positive group (P =0.018...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11676674	Figure 2 (panels A and B) displays the percentages of viable CHO-K1 cells treated with various concentrations of C. monspeliensis extract for 24 h, compared to untreated control cells (DMSO control).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	In recent years, patients with wild-type ELANE/G6PC3 were referred for targeted next generation sequencing, followed by whole exome sequencing.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "recent", "y...
PMC11267036	According to our data, p-STAT1/STAT1 and RIG-I levels in MM tumor plasma and cell lines were observably lowered relative to those in normal plasma and cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11673902	This low throughput limited the detection of large cell populations and hindered the generation of statistically significant data.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "low", "throughput", "limited", ...
PMC11637276	All washes were performed with PBS containing 1% antibiotic-antimycotic (anti/anti) to avoid contamination.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "washes", "were", "performed", "with", "PBS", ...
PMC11707577	3 h after the irradiation 16.95% of cells were apoptotic, 13% necrotic and 69.7% alive, while at 24 h necrosis predominated, accompanied by a remarkable decrease in cell viability.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11720107	By contrast, hesperidin, quercetin, resveratrol, and curcumin were shown to slightly decrease Pparγ mRNA expression, although the effects were not statistically significant.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11461874	Quantified intensities of Ub-Flag-DBP normalized by that of DBP are shown on the right by setting the mean of control cells to 1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Quantif...
PMC11711345	Programming: 50°C to 250°C at 20°C/min, held for 5 min.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Programming", ":", "50", "°", "C", ...
PMC9429973	Methods: Pts with MYD88 WM were assigned to cohort 1 and randomized 1:1 to receive ZANU 160 mg twice daily or IBR 420 mg once daily.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11754094	We have refined a long-range amplicon sequencing method to enable simultaneous analysis of both large deletions and small indels with high accuracy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "have",...
PMC9429973	In fact, our sample showed 100% of CR in NPM1+/FLT3-ITD- patients compared to 80% of NMP1+/FLT3ITD+ patients.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "fact", ",", "our...
PMC9581083	Although remdesivir has shown potent antiviral activities, more efficacy assessments are urgently warranted in clinical trials (Beigel, et al., 2020; WHO solidarity trial consortium, 2022).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9848491	The internal verification of the predictive signature for OS relied on TCGA-UCEC data. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "internal", "verification", "of", "the", "predictive", "signatur...
PMC11407042	Do not resuspend the culture medium after co-culture.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Do", "not", "resuspend", "the", "culture", "medium", "after", "co-culture", "." ] } ]
PMC11748335	= not significant).	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "=", "not", "significant", ")", "." ] } ]
PMC11803149	Repeated measures two-way ANOVA with Fisher’s LSD test, unpaired two-tailed t-tests and one-way ANOVA with Tukey’s multiple comparison test were used.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11228511	Increasing lamin B1 expression in progerin-expressing SMCs counteracted the impact of progerin on the structure of the nuclear lamina and reduced the frequency of nuclear blebs and ruptures.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11612508	Also, the highest degree of swelling was observed at a pH of 4.5, higher than at a pH of 7.4.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Also", ",", ...
PMC9429973	Summary/Conclusion: Patient enrollment is ongoing.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Summary/Conclusion", ":", "Patient", "enrollment", "is", "ongoing", "." ] } ]
PMC9429973	Aims: In this study, we aimed to evaluate the presence of sarcopenia and its effects on transplantation success in patients undergone stem cell transplantation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11519788	Equal amounts of protein from cell lysates were subjected to SDS-PAGE and transferred to PVDF membranes (Merck Millipore, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Equal", "amo...
PMC9429973	Twelve patients (27.2%) who had no sign of GvHD at the time of PRES developed GvHD in the follow-up after the treatment alteration, and 5 of these patients died due to severe GvHD during the follow-up.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11021472	This was unexpected since we did confirm a cytoplasmic localization similar to the endogenous circZDHHC11 and confirmed its ability to interact with miR-150 using AGO2-IP.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973	In secondary outcomes, compared to observation, lenalidomide maintenance was associated with a higher proportion of SAE (OR 4.64; 95% CI 2.96–7.26; I = 0%).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11478724	After overnight incubation, cells were treated with PMX (IC50 dose).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "overnight", "incubation", ",", "cells", "were", "treated", "with",...
PMC10998613	Along with our results on receptor antagonism, our data provide evidence that there is a complicated interplay between receptor structure, oligomerization, and signaling for GPCRs that has been previously underappreciated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5925824	Each data point represents the average of 8 replicates, with error bars representing the SEM.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Each", "data", "point", "represents", "the", "average"...
PMC11342785	Following stimulation, the fraction of clusters remaining over time was tracked by normalization to this initial post-stimulation value.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Following", "stimulation", ",", "...
PMC11092382	These authors further compared the effects of sophocarpine and sophoridine on hERG channels and showed that sophocarpine acted as a more potent hERG K channel blocker than sophoridine (Zhao et al., 2009).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10858941	Reagents were obtained from the following companies: NNC 55-0396 (357400-13-6) from Alomone, Israel; and bafilomycin-A (sc-201550) from Santa Cruz Biotechnology, USA.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7504302	In the study by Ishiguro et al., activated leukocyte cell-adhesion molecule (ALCAM/CD166), which is also a cancer stem cell marker, has been shown to be highly expressed in MPM.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11591794	In GA application to HaCaT cells, IC50 values could not be determined for 24, 48, and 72 h (Figure 2).	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ],...
PMC8711270	Expression of the T-antigen allows plasmids which carry the SV40 origin of replication to undergo replication when transfected into the cell (DuBridge et al., 1987).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11499955	The expression of PD-L1 was much lower than EGFR as determined via immunofluorescence analysis on ex vivo A431 tumor slices with the different antibodies of interest.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6461034	Effect of drug treatment in a patient with hypopharyngeal cancer.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Effect", "of", "drug", "treatment", "in", "a", "patient", "with", "hypopharyngeal", "cancer", ...

PMC10914904

The stem-loop structure in the apical region of vtRNA 1-1 enhances resistance to apoptosis by modulating the PI3K/Akt and ERK1/2 MAPK signaling pathways, with critical nucleotides for apoptosis resistance encircled in blue .

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PMC11621565

As previously stated, the discovery that PD pathological changes appear in the gastrointestinal tract has brought the gut microbiota into focus.

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PMC11705862

Similar glucolipotoxic conditions also caused downregulation of IRIS-1 and 2 in pancreatic β-cells, where they are involved in insulin granule exocytosis .

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PMC11643361

This review addresses recent findings on scorpionate complexes, emphasizing the impact of metal choice and ligand design on biological activity.

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PMC9429973

Most common AEs (n=38) were CRS (63%; all grade 1/2; median time to CRS onset: 3 d [range, 2–6], duration of CRS: 2 d [range, 1–4]), thrombocytopenia (42%; grade 3/4, 29%), neutropenia (55%; grade 3/4, 50%), lymphopenia (40%; grade 3/4, 37%), and anemia (39%; grade 3/4 29%), Grade 3 ICANS was reported in 1 pt which res...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10998613

Although the role of CXCR4 in cancer is widely reported, it is intriguing to find that it interacts with β2AR, an important protein in stress response.

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PMC11317131

PE insertion of att sites ranged from 0.3% to 62.1% as measured by amplicon sequencing using genomic primers flanking the insert (Figure 1B) and confirmed by droplet digital PCR (ddPCR), a form of quantitative PCR that reports highly accurate copy number of genomic inserts over a wide range of template concentrations (...

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PMC8662250

These observations had also been confirmed by a marked release of proinflammatory cytokines IL‐6, TNF‐α, each well‐known downstream product of TLR‐4 activation.

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PMC11740207

Their ability to exhibit pluripotency similar to iPSCs suggests that they have a higher proliferative potential than PGCs, supporting the hypothesis that VSELSCs originate from EpibCs through AD.

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PMC11799978

Two 10 cm Petri dishes were prepared, and CAFs cells were placed in cell culture dishes at a density of 3 × 10 cells per plate.

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PMC11723947

Data acquisition was performed on Symphony A5 (BD Biosciences) and analyses were carried out using FlowJo software.

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PMC2614415

Analysis was performed as described in Figure 3.

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PMC11407042

Shake the dish gently to ensure the even distribution of cells.g.

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PMC9878562

Deletion of blt1r was confirmed by genomic sequencing of the locus.

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PMC11612508

The biopharmaceutical characteristics of microspheres, their biodistribution, and the absorption of microsphere content can all be influenced by size.

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PMC7823217

Schematic diagram of a two-step 3D bioprinting method in which hiPSC-HPCs were patterned by the first digital mask followed by the patterning of supporting cells using a second digital mask.

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PMC11448304

g Subcellular localization of significantly regulated proteins Furthermore, the Motif-X tool was utilized to extract overrepresented patterns of Khib modification sites .

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PMC10530622

A classic example is the triad of primary hyperoxaluria, nephrolithiasis, and kidney injury.

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PMC11659734

Given the rising production of BPA alternatives, developed to replace BPA due to its concerned effects on human health, and the incomplete toxicological profiles of these compounds, there is an urgent need for comprehensive studies to assess their potential risks.

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PMC11706491

The cell cycle reporter strain was constructed in the following way: Sid2-GFP strain was obtained from elsewhere .

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PMC11588085

All experiments have been performed at least 3 times.

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PMC11519567

G Representative image of BJ fibroblasts expressing SS18-SSX1-EGFP when treated with 3% or 20% 1.6-hex.

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PMC11144382

Moreover, short-term treatment of murine primary calvarial osteoblasts with RA induced an increase in Crabp2 expression and other genes involved in retinol-dependent signaling and skeletal remodeling.

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PMC8992508

The TMD instead crosses the membrane and is composed of a number of transmembrane sequences, putative alfa-helices, separated by hydrophilic loops.

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PMC9780037

After its translation, cyt c is extensively imported into mitochondria.

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PMC11792766

Methanol, acetone, and acetonitrile did not present a notable decrease in the viability of the two aforementioned cell lines at 0.5% v/v concentration, whereas DMF and DMSO presented a borderline non‐statistically significant reduction (p‐value slightly above 0.05) in the viability of HepG2 and Caco‐2 cell lines.

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PMC3019555

HeLa–GFP-Ago2 cells were incubated in glucose-free media for 1 h and stained for α-tubulin (white).

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PMC11759751

By the 12th day, transduction efficiency was assessed using flow cytometry to determine the percentage of CAR-T 19 cells within the CD3+ T cell population.

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PMC11697703

During neural development, MapK8 controls multiple processes including cell death, proliferation, soma size, migration, and dendritic arborization.

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PMC11802855

In both H929 and RPMI 8226 cell lines, the levels of p-JAK1 and p-STAT3 were significantly increased in CXCL7-OE group (Fig. 6E).

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PMC10495912

Cell membrane integrity As shown in Figure 4-D, no significant changes were observed following the exposure of HepG2 cells to different doses of TQ and hydrogen peroxide alone.

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PMC7053076

The most potent analog of the series, (R)-3-(4-bromophenyl)-1-ethyl-5-methylidene-6-phenyldihydrouracil, designated U-332 (Fig. 1), caused in HL-60 cells excessive DNA damage which led to the cell cycle arrest in G2/M phase and apoptosis.

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PMC11687663

It involves simulating the interaction between the two molecules to predict the most energetically favorable binding pose .

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PMC10926885

In order to fill the research gap pertaining to the impact of NDE1 on the genesis and progression of cancer, our study also included experimental investigations aimed at elucidating the role of NDE1 in facilitating the proliferation, migration and invasion of bladder cancer cells.

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PMC11047729

It lowers the expression of hTERT and c-myc mRNA through protein kinase C inhibition .

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PMC11766332

Notably, the study identified ASD-miRNA targets that include glycogenes, whose detrimental mutations are linked to congenital disorders of glycosylation—metabolic conditions with significant neurological involvement, including ASD.

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PMC11750712

At the highest dose level (450 × 10 CAR T cells), all four patients achieved an objective response with three patients achieving CMR and one patient achieving a PR by PET-CT.

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PMC9429973

Response rates with the combination were encouraging in frontline and salvage, with favorable OS.

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PMC9878562

The expression of enzymes involved in LTB4 production suggested that CXCL12 and LTB4 could act synergistically in stimulating VAL-wt migration through a positive feedback loop.

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PMC11686380

Scale bar, 50 μm. (

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PMC10993311

Likewise, the significant biological covariates identified by SVD analysis showed slightly different patterns in each group, indicating that hs-CRP in T3, length In T3, and FL in T3 may be related to the epigenetic signature.

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PMC10654497

Therefore, lung cancer is often associated with resistance to a variety of targeted treatments.

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PMC9429973

Effectiveness endpoints were change from baseline (CFB) to 48 weeks in hemoglobin (Hb), red blood cell (RBC) transfusions, lactate dehydrogenase (LDH), absolute reticulocyte count (ARC), and % PNH RBCs relative to PNH white blood cells (WBC).

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PMC11592837

Since DOX-treated PBMCs displayed no elevated cell death and a markedly decreased n-cfDNA integrity index at later time points, we speculate whether a protective cellular response to DOX potentially reduced cytotoxity until 8 h. In drug-treated Jurkat cells, higher cell death-specific γH2AX staining, increased mt-cfDNA...

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PMC9504875

This study elucidated new strategies for how nairoviruses evade host IFN systems.

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PMC5034105

None of the mouse, rat and bat cell lines showed a ⩾2 log increase in viral load within 5 d.p.i.

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PMC11772585

HSC-1 and A431 cells were seeded in 6-well plates and cultured for 24 min.

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PMC4443654

Finally we used model predictions to examine boundary composition between higher-order domains across cell types.

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PMC11026382

The standard error in growth rate was computed across triplicate measurements.

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PMC11680391

We retrieved information from the National Danish Cattle Database.

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PMC10589262

A Activation status of the three arms of the unfolded protein response (UPR) pathway (ATF6, IRE1α, and PERK) was measured by western blotting in a panel of cancer cell lines expressing WT-KIT or MT-KIT.

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PMC9429973

Other dynamic states patients could enter and leave during follow-up were treatment & no transfusion, transfusion & no treatment and no treatment & no transfusion (considered as TTT-free survival).

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PMC10582049

Projection of samples isolated from indolent and aggressive LUADs within stromal cell subpopulation (right). (

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PMC11486946

The preparation process for EGFR-transfected Ba/F3 cells was almost the same as that for other cells, except that floating cells in Eppendorf tubes were centrifuged with 800 × g for 2 min to replace the supernatant after every step.

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PMC11753435

For immunocytochemistry, the cells were gently shaken in blocking buffer [5% (v/v) normal goat serum (Jackson ImmunoResearch) and 0.2% (v/v) Triton X-100 in 1× PBS] at RT for 1 hour, followed by overnight incubation in the blocking buffer with primary antibodies at 4°C.

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PMC11190238

Fig. 2Hierarchical order of the 3D genome.

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PMC11365983

Fig. 4Foxc1 alters the dynamics of Hh signaling and enhances Gli2 accumulation at the ciliary tip. (

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PMC10093184

COS3600B and COS4288 cells produced visible colonies after anchorage-independent growth in soft agar.

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PMC9429973

Thrombocytopenia is defined by platelet level lower than 150,000/uL. Incidences of thrombocytopenia and related complications were recorded and analyzed.

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PMC10761571

As was observed in this work, treating lung adenocarcinoma cells with Fe3O4@Glu-Gingerol led to upregulation of the CASP8 and BAX genes, while it down-regulated the BCL2 gene.

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PMC9429973

The combination of azacitidine with bexmarilimab augmented HLA-DR induction by 20-110% (mean 44%).

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PMC3122064

Moreover, treatment with RITA induced caspase-dependent apoptosis in NCCIT, the TC cell line expressing mutant p53 (Supplementary Figure 2a), indicating that at least in TC cells RITA induces apoptosis independent of wild-type p53.

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PMC8633974

Our data establish an association between tat/rev target DNA conservation and CRISPR-Cas9 efficacy across multiple HIV-1 transmitted founder strains (Figure 2b).

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PMC9429973

Univariate and multivariate logistic analysis of potential influencing factors for CR rate showed that CD200 was an independent influencing factor for CR rate after the first course of chemotherapy, and the probability of obtaining CR in the CD200 negative group was 4.15 times that of the CD200 positive group (P =0.018...

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PMC11676674

Figure 2 (panels A and B) displays the percentages of viable CHO-K1 cells treated with various concentrations of C. monspeliensis extract for 24 h, compared to untreated control cells (DMSO control).

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PMC9429973

In recent years, patients with wild-type ELANE/G6PC3 were referred for targeted next generation sequencing, followed by whole exome sequencing.

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PMC11267036

According to our data, p-STAT1/STAT1 and RIG-I levels in MM tumor plasma and cell lines were observably lowered relative to those in normal plasma and cells.

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PMC11673902

This low throughput limited the detection of large cell populations and hindered the generation of statistically significant data.

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PMC11637276

All washes were performed with PBS containing 1% antibiotic-antimycotic (anti/anti) to avoid contamination.

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PMC11707577

3 h after the irradiation 16.95% of cells were apoptotic, 13% necrotic and 69.7% alive, while at 24 h necrosis predominated, accompanied by a remarkable decrease in cell viability.

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PMC11720107

By contrast, hesperidin, quercetin, resveratrol, and curcumin were shown to slightly decrease Pparγ mRNA expression, although the effects were not statistically significant.

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PMC11461874

Quantified intensities of Ub-Flag-DBP normalized by that of DBP are shown on the right by setting the mean of control cells to 1.

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PMC11711345

Programming: 50°C to 250°C at 20°C/min, held for 5 min.

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PMC9429973

Methods: Pts with MYD88 WM were assigned to cohort 1 and randomized 1:1 to receive ZANU 160 mg twice daily or IBR 420 mg once daily.

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PMC11754094

We have refined a long-range amplicon sequencing method to enable simultaneous analysis of both large deletions and small indels with high accuracy.

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PMC9429973

In fact, our sample showed 100% of CR in NPM1+/FLT3-ITD- patients compared to 80% of NMP1+/FLT3ITD+ patients.

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PMC9581083

Although remdesivir has shown potent antiviral activities, more efficacy assessments are urgently warranted in clinical trials (Beigel, et al., 2020; WHO solidarity trial consortium, 2022).

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PMC9848491

The internal verification of the predictive signature for OS relied on TCGA-UCEC data. (

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PMC11407042

Do not resuspend the culture medium after co-culture.

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PMC11748335

= not significant).

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PMC11803149

Repeated measures two-way ANOVA with Fisher’s LSD test, unpaired two-tailed t-tests and one-way ANOVA with Tukey’s multiple comparison test were used.

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PMC11228511

Increasing lamin B1 expression in progerin-expressing SMCs counteracted the impact of progerin on the structure of the nuclear lamina and reduced the frequency of nuclear blebs and ruptures.

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PMC11612508

Also, the highest degree of swelling was observed at a pH of 4.5, higher than at a pH of 7.4.

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PMC9429973

Summary/Conclusion: Patient enrollment is ongoing.

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PMC9429973

Aims: In this study, we aimed to evaluate the presence of sarcopenia and its effects on transplantation success in patients undergone stem cell transplantation.

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PMC11519788

Equal amounts of protein from cell lysates were subjected to SDS-PAGE and transferred to PVDF membranes (Merck Millipore, USA).

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PMC9429973

Twelve patients (27.2%) who had no sign of GvHD at the time of PRES developed GvHD in the follow-up after the treatment alteration, and 5 of these patients died due to severe GvHD during the follow-up.

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PMC11021472

This was unexpected since we did confirm a cytoplasmic localization similar to the endogenous circZDHHC11 and confirmed its ability to interact with miR-150 using AGO2-IP.

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PMC9429973

In secondary outcomes, compared to observation, lenalidomide maintenance was associated with a higher proportion of SAE (OR 4.64; 95% CI 2.96–7.26; I = 0%).

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PMC11478724

After overnight incubation, cells were treated with PMX (IC50 dose).

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PMC10998613

Along with our results on receptor antagonism, our data provide evidence that there is a complicated interplay between receptor structure, oligomerization, and signaling for GPCRs that has been previously underappreciated.

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PMC5925824

Each data point represents the average of 8 replicates, with error bars representing the SEM.

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PMC11342785

Following stimulation, the fraction of clusters remaining over time was tracked by normalization to this initial post-stimulation value.

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PMC11092382

These authors further compared the effects of sophocarpine and sophoridine on hERG channels and showed that sophocarpine acted as a more potent hERG K channel blocker than sophoridine (Zhao et al., 2009).

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PMC10858941

Reagents were obtained from the following companies: NNC 55-0396 (357400-13-6) from Alomone, Israel; and bafilomycin-A (sc-201550) from Santa Cruz Biotechnology, USA.

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PMC7504302

In the study by Ishiguro et al., activated leukocyte cell-adhesion molecule (ALCAM/CD166), which is also a cancer stem cell marker, has been shown to be highly expressed in MPM.

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PMC11591794

In GA application to HaCaT cells, IC50 values could not be determined for 24, 48, and 72 h (Figure 2).

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PMC8711270

Expression of the T-antigen allows plasmids which carry the SV40 origin of replication to undergo replication when transfected into the cell (DuBridge et al., 1987).

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PMC11499955

The expression of PD-L1 was much lower than EGFR as determined via immunofluorescence analysis on ex vivo A431 tumor slices with the different antibodies of interest.

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PMC6461034

Effect of drug treatment in a patient with hypopharyngeal cancer.

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