PMCID
string
Sentences
string
ner
list
PMC10587429
Flow cytometry antibody panel for evaluation of human engraftment in NSG-SGM3 mice.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "Flow", "cytometry", "antibody", "panel", "for", "evaluation", "of", "human", ...
PMC11512230
Our group has previously shown that AltMV SPV and AltMV SPVLP contain lysine and cysteine residues that are potentially accessible for conjugation .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Our", "group...
PMC11248911
C NMR (DMSO-d6, δ ppm): 16.24, 31.69, 46.45, 63.11, 125.80, 127.18, 128.86, 143.87, 157.89, 176.49.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11423992
To evaluate the activation of T cells by TFAB002s, co-cultures were established using WIL2-S cells and Jurkat cells that stably express the NFAT-luciferase reporter gene.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "...
PMC11449273
Since there are no currently available cancer cell lines that endogenously express all three proteins (plakoglobin, p53-R273H and p53-R175H), we used the p53-null and plakoglobin-deficient H1299 non-small cell lung carcinoma cell line for our studies and exogenously expressed plakoglobin, p53-R273H and p53-R175H at res...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10728535
There has been increasing interest in the use of integrated analysis for examining multiple independent microarray data sets.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "There", "has", "been", "increasing", "...
PMC11787381
Fig. 5Effects of a formulation of bambuterol on locomotor activity and anxiety in mice in the open-field test.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fig.", "5Effects", "of", "a", "formula...
PMC9712534
Experiments were repeated 3 times as described in (a).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Experiments", "were", "repeated", "3", "times", "as", "described", "in", "(", "a", ...
PMC10996034
On the other hand, it has been shown that physical confinement during cancer cell migration triggers therapeutic resistance (50).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "On", "the", ...
PMC10222971
These results are shown in dot plots, where the LL quadrant represents viable cells (both Annexin V and PI negative), the LR quadrant represents unviable cells (PI positive and Annexin V negative), the UL quadrant represents cells in early apoptosis/cell apoptosis (Annexin V positive and PI negative) and UR quadrant re...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8481254
Moreover, YAP can promote the synthesis of HBP metabolites and cellular O-GlcNAcylation; therefore, YAP and O-GlcNAcylation can promote each other to establish a positive feedback loop.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11795610
After Hoechst 33,258 staining, the nucleus of viable cells is normally blue, while the nucleus of apoptotic cells appears abnormally bright white color.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11640247
While the activation of PAK1, MLK2, and N-WASP by RAC3-R66W likely plays an essential role in the pathophysiology of the severe prenatal manifestations, these effectors do not seem to influence SRF, NFκB, or AP1-mediated gene expression, which are essential for cell growth and proliferation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6442998
In GIST882 cells, activation of oncogenic KIT downstream pathways is modest (i.e. sensitive to imatinib).
[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "GIST882", "cells", ",", ...
PMC11277157
We identified STAT3 as a hub that connect stress, inflammation with transcription regulation (e.g., EGR1 and ATF3), and the DNA repair and cell cycle axis (CDKNA1 and DDB2).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6222726
From this extract, Velazquez-Jimenez et al. isolated two aryltetraline lignans: (−)-deoxypodophyllotoxin (15) and (−)-morelensin (16) (Figure 3), and two dibenzylbutirolactone lignans: (−)-yatein (17) and (−)-5′-desmethoxy yatein (18) or bursehernin] (Figure 1) .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5034105
The differential cell line susceptibility of our nonhuman cell lines to ZIKV may provide insights into the virus' potential animal reservoirs and alternative animal models.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9856122
A few alkaloids such as columbamine iodide and jatorrhizine chloride also showed activity against HIV with IC50 values of 58 and 71 µg/mL respectively .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11643361
These hard-to-reconcile results suggest that more focused or larger panels of cell lines, as well as expanded sets of activity assays, need to be systematically employed to accurately assess the biological activity of these metal complexes.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11782508
Potentially therapeutic bacterial peptides offer several advantages.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Potentially", "therapeutic", "bacterial", "peptides", "offer", "several", "advantages", "." ] } ]
PMC11655536
Cells were treated with HA at indicated concentration for 48 h. H The effect of HA on cell viability in ten primary MM patient cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9341513
This means that we can make predictions about the 3D structure of cell types or tissues where Hi-C data is not available.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "mean...
PMC10788478
p‐values <0.05 were considered statistically significant.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "p‐values", "<", "0.05", "were", "considered", "statistically", "significant", "." ] } ]
PMC9784246
Overall, scores of binding affinities of identified ligands suggest that the best binding ligands as inhibitors for HDAC6 mainly belong to epicatechin/catechin glycosides in which the glucosides moiety is essential for interactions.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11093197
We discovered that pS62 and pT58 of c‐Myc were considerably decreased in RB1‐deficient cells (Figure 2B), while the mRNA level of c‐Myc was unaffected by RB1 loss (Figure S9).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11678130
The data obtained from three individual tests for the experiments were statistically evaluated using the GraphPad Prism software, version 10.2.3 (GraphPad Software, San Diego, CA, USA, www.graphpad.com) and by employing two statistical methods: a one-way ANOVA and Dunnett’s multiple comparison test.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11547972
The Bliss independence analysis verified synergistic interactions between amygdalin and SFN.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "Bliss", "independence", "analysis", "verified", "synergistic", "interactions", "between", ...
PMC9429973
Supported by MH CZ-DRO-VFN64165, DRO-UHKT00023736.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Supported", "by", "MH", "CZ-DRO-VFN64165", ",", "DRO-UHKT00023736", "." ] } ]
PMC11568601
The 143B and MG-63 cells were treated with different concentrations of TGT.
[ { "tags": [ "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "143B", "and", "MG-63", "cells", "were", "treated", "with", ...
PMC10170482
Quantification of three independent experiments. (***)
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Quantification", "of", "three", "independent", "experiments", ".", "(", "*", "*", "*", ")"...
PMC9429973
Any of three TKIs (imatinib, nilotinib, dasatinib) can be used in the first treatment line (I TL).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Any", ...
PMC8010066
Also, a slight decline of KPC expression level was observed in the PA-4 strain (P-value ≤ 0.001).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Also", ",", "a", ...
PMC10588957
The expression of AMPK and p-AMPK was detected by pre-incubating HepG2 cells for 1 h in the absence or presence of an AMPK inhibitor (Compound C).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11357960
Association between the percentage change in UBE2I mRNA level and different white blood cell populations in peripheral blood of lung cancer patients. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Associa...
PMC11748363
Tuberculosis (TB) is an old infectious disease for which eradication has not yet been successful.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Tuberculosis", "(", "TB", ")", "is", "an", ...
PMC11298021
In Jurkat cells transfected with miR-3143 and treated with rapamycin, the mRNA expression of PI3K, AKT, mTOR, and S6KB1 genes was significantly decreased ( *** P<0.001, **** P<0.0001). (
[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9926039
While moderate morphine dose decreased TLR4 gene expression, it had a reverse effect in higher concentrations.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "While", "moderate", "morphine", "dose", "decrease...
PMC11747949
The VEGF‐VEGFR axis is implicated in tumor neo‐angiogenesis and represents a prognostic marker in osteosarcoma patients (Zhang et al. 2021).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "VEGF‐...
PMC11670407
The collected tumor tissues were embedded and sectioned for subsequent immunohistochemistry.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "collected", "tumor", "tissues", "were", "embedded", "and", "sectioned", "for", ...
PMC11106977
This process may also be essential for osteoclast differentiation .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "process", "may", "also", "be", "essential", "for", "osteoclast", "differentiation", "." ] } ]
PMC9220170
It is known that seven mammalian selenoproteins are localized in the endoplasmic reticulum: SELENOM, SELENOT, SELENOF, SELENOK, SELENOS, SELENON, and DIO2.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11621493
β-Actin served as loading control.
[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "β-Actin", "served", "as", "loading", "control", "." ] } ]
PMC9429973
Response rates will be analyzed with estimates and 95% confidence intervals based on exact binomial distribution.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Response", "rates", "will", "be", "analyzed", ...
PMC10976516
Seyed-Khorrami et al. used MSCs loaded with oncolytic reovirus in the syngeneic mouse TC-1 lung cancer model and tested their migratory potency in vivo after systemic infection and assessed the efficacy and quality of lung cancer treatment.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11732628
The cDNA was amplified by qPCR using a SYBR green PCR Master Mix kit Takara, Toyobo, Japan).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cDNA", "was", "...
PMC9429973
To date, it is unclear when these niche alterations occur and how they contribute to disease progression.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "date", ",", "it", "is", "u...
PMC11607638
Dulbecco's Modified Eagle's Medium (DMEM)/F12 medium (#C11330500BT) and fetal bovine serum (FBS) (#10099141) were bought from Thermo Scientific (Shanghai, China).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4443654
Strong and significant correlations are seen between cell types for a variety of human higher-order domains, delineating variation in replication timing, lamin association and nuclear compartments derived from Hi-C eigenvectors .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7057940
In addition, lysine-specific demethylase 3A has been reported to cause this silencing in tumorigenic ES scenarios (16).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "addition", ",", ...
PMC9429973
Secondary endpoints were the assessment of safety and tolerability of the treatment, the immunologic modifications induced by the procedure and the clinical response to treatment.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11574271
We performed KEGG and GO analysis on these genes and combined the annotations in the GENE database to screen 13 genes that are directly related to cell migration and invasion (which include RON) (Fig. 2B).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11730311
The plasma supernatant was stored at − 70 °C until analysis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "plasma", "supernatant", "was", "stored", "at", "−", "70", "°", "C",...
PMC9622879
The performance of our proposed CEMS is evaluated by applying to different communities with different number of homes.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "performance", "of", "our", "pro...
PMC11791478
XB002, which was generated by conjugating 25A3 to the linker–payload, zovodotin (Fig. 2), had a DAR of ∼3.8 as determined from the calculation of peak areas from the reduced reverse-phase HPLC (Supplementary Fig. S3A).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Significantly higher levels of NK cells: CD56dimCD16+ (median 8.93 vs 14.23%, p<0.01) and CD56brightCD16- (median 0.33 vs 0.52%, p=0.02) were found in men compared to women 3 months after withdrawal.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11306331
FRB/FKBP dimerize in response to rapamycin.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "FRB/FKBP", "dimerize", "in", "response", "to", "rapamycin", "." ] } ]
PMC8992508
Some of the derivatives were also interesting MRP1 inhibitors, and some of them were efficacious in inhibiting BCRP.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Some", "of", "the", "derivatives"...
PMC9429973
BcR IG reactivity profiling was performed for 6 LC-MBL cases, 10 HC-MBL cases and 9 CLL cases against 123 autoantigens using a protein microarray; validation tests were performed with ELISA.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11472639
Data are mean ± SD, n = 8.Table 4Cells/μLPhenotypePre-exercisePost-exercise30-min post-exercise%Δ pre- to post-exerciseEffect of timePlasma cellsCD38CD1382.6 ± 5.65.4 ± 12.62.9 ± 6.258 ± 41F(1.00,7.00) = 1.25, p = 0.30, ηp = 0.15CD38CD138CD45CD19 (with light-chain restriction)2.1 ± 5.54.7 ± 12.32.3 ± 6.1121 ± 95F(1.00,...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Among luspatercept pts, 13/153 (8.5%) progressed to HR-MDS/AML during the entire Tx period, compared with 5/76 (6.6%) placebo pts.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7987994
Significance codes according to p value: 0 ‘***’0.001 ‘**’0.01 ‘*’0.05 (two-sample t-test).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11718031
Fig. 3VCC and viability of cell cultures grown with different media-feed combinations VCC and viability of cell cultures grown with different media-feed combinations For IS CHO-G17.4 and IS CHO-G17.7, the cell viability of the fed-batch culture with all seven different feeds dropped down to below 80% after 8 days.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", ...
PMC11543935
Hydrogels were cultivated for 24 h before EP.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Hydrogels", "were", "cultivated", "for", "24", "h", "before", "EP", "." ] } ]
PMC9812014
two of them, flavesine-J and alopecurine-B alkaloids showed significant repressive activities by targeting the HBsAg and HBeAg secretions.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "two", "of", "them", ",", "f...
PMC11700523
MR transcriptional activity was investigated by luciferase assays, and protein levels were measured by Western blotting.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "MR", "transcriptional", "activity", "was", "inves...
PMC11462929
A recent report demonstrated that EBNA2 upregulates MYC expression via the formation of a super‐enhancer at the regions 428 and 525 Kbp upstream of the transcription start site of MYC.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10887351
S, Gα.
[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "S", ",", "Gα", "." ] } ]
PMC8357004
Besides maximal apoptosis was seen in the combined treatment groups after 48 h of treatment (P < 0.001), Figure 5.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Besides...
PMC11345828
NH4Cl, sat.
[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "NH4Cl", ",", "sat", "." ] } ]
PMC5716223
The results showed that, under serum deprivation, the activity of CS and GAPDH, both involved in carbohydrates metabolism, was increased by NGF supplementation compared to control (CS: 21.7 and 55.2% increase for NGF 10 and 100 ng/ml respectively; GAPDH: 37.7 and 95.7% increase for NGF 10 and 100 ng/ml respectively (p ...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11363012
The brown arrow indicates the group of cells that accumulates primarily flavonoids and secologanin (2).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "brown", "arrow", "indicates", "the", ...
PMC10777969
These results suggest that FCP23 acts in a manner similar to FCP6.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "results", "suggest", "that", "FCP23", "acts", "in", "a", "manner", ...
PMC11745823
The expression level is frequently elevated abnormally in several main or secondary malignant tumour tissues .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "expression", "level", "is", "frequently", "elevated", ...
PMC4695073
Kaplan-Meier and log-rank tests were used to analyze patient survival time and curves.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Kaplan-Meier", "and", "log-rank", "tests", "were", "used", "to", "analyze",...
PMC8973725
Figure 1.The online database showed that ZNF677 was considerably downregulated in tumor tissues. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Figure", "1.The", "online", "database", "showed", "that", "ZNF677", ...
PMC7553912
In addition, αSMA and Timp2 were increased on day 3 and day 6 compared with those on day 0 in WT mice (Fig. 3k,l).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11638288
When M. tuberculosis infects mononuclear phagocytes, vimentin expressed on the surface of monocyte-macrophages binds to NKp46 on the surface of NK cells NKp46 and then causes NK cells to lyse macrophages engulfing Mycobacterium tuberculosis The molecular mechanism and function of NKp46 in combating M. tuberculosis infe...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11763764
All reactions were performed with 5 biological replicates.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "reactions", "were", "performed", "with", "5", "biological", "replicates", "." ] } ]
PMC11388384
Because SHH-Halo transitioned between diffusible populations very rapidly, we were forced to consider extremely short integration times (3 localization intervals, 18 ms) introducing error in the measurement of each population’s diffusion coefficient.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Secondary and exploratory endpoints include the proportion of pts with a reduction in transfusions ≥33% and ≥50%, respectively, over 12 wks; reduction in transfusions over 12, 24 and 48 wks (Cohorts A/B); Hb response at Wks 24 and 48; and change from baseline in Hb over 12, 24 and 48 wks (Cohort C).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6642070
This evidence promotes us to investigate whether statins affect lactate levels and their role in SAMS in mice.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "evidence", "promotes", "us", "...
PMC9429973
Moreover, they were characterized by reduced Ks (-22%, p<0.001) and prolonged CLT (+30%, p<0.001).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC4360730
This includes experimentally derived samples, heterogeneous cell populations derived from cultures and other biological components commonly used in experiments that do not have a singular anatomical term (15).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11078693
Centrifuge the cells at 200 g and 4°C for 10 min.i.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Centrifuge", "the", "cells", "at", "200", "g", "and", "4", "°", ...
PMC11607321
To ensure fair comparisons, conditionals were not incorporated into any of the selected methods during training.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "ensure", "fair", "comparisons", ",", ...
PMC11806106
Sensor S266: same as M264, besides fragment 1 rev: CCCTTGCTCACCATCCGCGGCGATAGCATGCGAACGCTC; YFP fwd: TTCGCATGCTATCGCCGCGGATGGTGAGCAAGGGCGAG; YFP rev: TTTTCTTTGGAGCCGTTAACCTTGTACAGCTCGTCCATGCCG; fragment 2 fw: ACGAGCTGTACAAGGTTAACGGCTCCAAAGAAAAGGACAGGAATCT.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11740207
Unlike LT-HSCs, ST-HSCs express surface markers such as CD34 and CD38 but not CD90, correlating with their rapid differentiation capacity (Wilson et al., 2007; Cabezas-Wallscheid et al., 2014; Zeng et al., 2022).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5925824
Biacore T200 Evaluation Software (version 1.0) was used to analyze the results from the kinetic experiments.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Biacore", "T200", "Evaluation", "Software", ...
PMC11756514
Subsequently, the bacteria were washed twice and incubated with 0.5 µg/mL streptavidin-BV421 (BD Bioscience).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Subsequently", ",", "the", "bacteria", "were", ...
PMC11583010
The Fc fragment includes amino acid substitutions (L234F, L235E, and P331S) to reduce FcγR binding (Fig. 3A).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...
PMC11670954
.
[ { "tags": [ "O" ], "tokens": [ "." ] } ]
PMC11568601
The in vivo validation confirmed that TGT stimulated osteosarcoma cell apoptosis through the ER stress-associated IRE1/CHOP pathway in vivo, accompanied by an increase in the expression of p-IRE1 and CHOP in tumor tissues.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11552389
But FSIP1 expression is not statistically significant (Figure 1C).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "But", "FSIP1", "expression", "is", "not", "statistically", "significant", "(", "Figure", ...
PMC11240448
Thus, it is important to evaluate which data types cSTAR can use and how well it can cope with the sparseness and noisiness of biological and biomedical data.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9436459
After acylation of S100 with thionyl chloride, the crude product benzoyl chloride S101 was directly conducted with S99 to form an acyloxy ketone, which was then converted into β-diketone S102 through a base-catalyzed Baker–Venkataraman rearrangement.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10565698
In parallel with the changes in cell phenotype, the expression of some proteins was altered.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "parallel", "with", "the", "changes", "in", ...
PMC2193049
Finally, reciprocal transplantation of the MAGE-3271–279 sequence into unrelated proteins indicated that the impaired generation of the antigenic peptide was not caused by residues flanking peptide MAGE-3271–279 (data not shown).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4443654
Acc.,
[ { "tags": [ "O", "O", "O" ], "tokens": [ "Acc", ".", "," ] } ]
PMC11477621
HRMS (ESI), m/z: calcd for C24H22ClN6O2: 461.1498 [M − H]; found: 461.1500.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "HRMS", "(", "ESI"...
PMC11155445
After performing titration three pKa values were found for three protonated sites LH, LH2, and LH3.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "performing", "titration", "three", ...