OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC11718274	Consistency with ROS generation results, biochemical measurement of oxidative stress markers demonstrated remarkable induction of oxidative stress within A-431 cancer cells by Y2O3NPs treatment in a concentration-dependent manner compared to both control and doxorubicin-treated A-431 cancer cells (Table 4).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", ...
PMC11734514	1.53e (NIH).	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "1.53e", "(", "NIH", ")", "." ] } ]
PMC7022782	Cells were put in contact for 1 h with unloaded NPs and ICG-NPs1, washed, and fixed with a solution containing 2.5% glutaraldehyde and 2% paraformaldehyde in 0.1 M Na-cacodylate buffer (pH 7.4) for 6 h at 4 °C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11617590	GSK‐3β is a serine/threonine kinase that plays a role in the development of pancreatic ductal adenocarcinoma (PDAC) by cell proliferation, survival, invasion, metastasis, and resistance to chemotherapy .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11673902	This process can be divided into two steps: First, water molecules penetrate the bilayer to form an unstable hydrophobic pore, and then the polar head groups of adjacent lipids are redirected toward these water molecules to form a stable hydrophilic pore, allowing polar molecules to enter the cell .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11407042	Avoid doing this in 96-well plates, as it may damage cells and cause LDH release.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Avoid", "doing", "this", "in", "96-well", "plates", ...
PMC11742047	Data in the column bar represent the mean ± SD of three different experiments done in triplicate.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "in", "the", "column", "bar", "repre...
PMC11750165	In wild-type zebrafish embryos, the neural progenitors in the p3 domain divide into two between 9-hpf and 16-hpf; one becomes KA” neuron, whereas the other should remain as a progenitor for next stage of neurogenesis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9985266	Then, the sample was sliced into 5-µm-thick paraffin sections after dehydration and embedding.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Then", ",", "the", "sample", "was", "sliced", "into", "5-µm-thic...
PMC11476106	The cytoplasm was generally thin, with limited intercellular spaces, and minimal eosinophilic material (Figure 3E–H).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cytoplasm", ...
PMC9429973	It also may have been impacted by the COVID-19 pandemic.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "also", "may", "have", "been", "impacted", "by", "the", "COVID-19", "pandemic", "." ...
PMC9693627	ImageJ software (NIH, Bethesda, MD, USA) was used for quantification.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ImageJ", "software", "(", "NIH", ",", "Bethesda", ",", ...
PMC7185206	Additional analyses across the TCGA dataset are reported in Supplemental Figure 1 and Supplemental Tables 1–2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additional", "analyses", "across", "the", "TCGA", "dat...
PMC9429973	TRAD::MYC translocation confers aberrant MYC expression and hyperproliferative of tumor cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "TRAD::MYC", "translocation", "confers", "aberrant", "MYC", "expression", "and", "hyperproliferati...
PMC8956657	CoIP’s were repeated twice for IMPα1 and α5 and three times for IMPα3.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CoIP", "’s", "were", "repeated", "twice", "for", "IMPα1", "and",...
PMC10142392	The authors then performed a deprotection of the tert-butyl group from the PCL-µ-PtBA copolymer, and their studies showed a flat and smooth surface, which was due to the good miscibility of PCL and PAA segments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11462673	B Western blotting analysis showed that MYB, PARP and GAPDH protein pression in 6 T-CEM and J.gamma1 cells after the effects of MBZ.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O"...
PMC10890055	Continuous cell lines represent an unlimited cell source for testing, since they can proliferate indefinitely.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Continuous", "cell", "lines", "represent", "an", "unli...
PMC11592008	All cell lines had similar mRNA expression levels of PYCARD (Figure 1E).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "cell", "lines", "had", "similar", "mRNA", "expression", "...
PMC11727062	In another study, the combined effect of evodiamine and vemurafenib on A375 cells was investigated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O" ], "tokens": [ "In", "another", "study", ",", "the", "combine...
PMC10671321	Interaction of ColQ with this complex is necessary for the synaptic localization of ColQ, since LRP4 and MuSK are strictly expressed at the post-synaptic membrane, but two heparin binding sites located in ColQ collagen domain are also indispensable for anchorage of the enzyme in the synaptic basal lamina .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9739791	JC-1 assay, which allows determination of how mitochondria membrane potential is changed upon exposure to the drug, demonstrated a significant loss of mitochondrial membrane integrity when cells with the Pt(IV) prodrug 27 were irradiated, while the almost negligible effect was observed when cells were treated with the ...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8806312	The formula for the risk score of every OS patient was constructed: risk score = [CD79A * (−1.926)] + [CSF3R (−1.4990)] + [MTNR1B (2.3731)] + [NPPC * (1.1894)].	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11750165	T7E1 assay showed that multiple bands in two out of four embryos.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "T7E1", "assay", "showed", "that", "multiple", "bands", "in", "two", "out", ...
PMC8557138	Further, a few studies have highlighted the prospective of electrical stimulation in promoting angiogenesis, however, most of these studies are preliminary in vitro studies, for instance, basic alignment studies under directional electrical fields of 150–400 mV/mm for different cell types like pulmonary artery fibrobla...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10758402	Subsequently, these cells were infected with HSV.n212 that was genetically modified to express green fluorescent protein, at a low multiplicity of infection (MOI), as shown in ( Figure 1A ).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11633763	After washing, the beads were resuspended in 20 μL of IP buffer, followed by the addition of protein buffer and boiling for 10 min.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9352806	YA: young adult. (	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "YA", ":", "young", "adult", ".", "(" ] } ]
PMC9429973	Other COVID19 strains were very unlikely to be present given the low prevalence in Victoria during the period of study.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Other", "COVID19", "strains"...
PMC9429973	We studied population-based outcomes in CMML using the NCDB from 2004-2017.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "studied", "population-based", "outcomes", "in", "CMML", "using", "the...
PMC11365427	During phenylalanine deprivation in MM cells, ATF3 expression was stimulated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "During", "phenylalanine", "deprivation", "in", "MM", "cells", ",", "ATF3", "expression", ...
PMC11467964	Meanwhile, a box plot comparing infiltration levels of the human immune cells was generated (Figure 3B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Meanwhile", ",", "a", "box", ...
PMC9164404	Specifically, in the Abplatin treated group, twenty phosphatidylcholine (PCs), three phosphatidylglycerols (PGs), four lysophosphatidylcholines (LPCs), one lysophosphatidylethanolamine (LPE), one sphingomyelin (SM) and two lysosphingomyelins (LSMs) were up-regulated compared with the PBS treatment group.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11772585	Among these modifications, N7-methylguanosine (m7G) modification was identified as a prevalent posttranscriptional RNA modification that affects tRNAs, rRNAs, miRNAs, as well as mRNAs, playing critical roles in RNA processing, metabolism, and functions .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5941560	Overlaps between duplication and inversion calls were determined less stringently.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Overlaps", "between", "duplication", "and", "inversion", "calls", "were", "determined", "less", ...
PMC9919300	The hepatoprotective activity of curcumin is controversial, with reported cases of hepatotoxicity with curcumin dietary supplementation, which lead the Italian Health Ministry to discourage its administration in subjects with liver function alterations.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11476264	It is often accompanied by metastases in late stages .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "is", "often", "accompanied", "by", "metastases", "in", "late", "stages", "." ] } ]
PMC10936243	the welfare, just that sometimes, they’ve been dragging with too much workload and everything, and then they want everything to work fast.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11371627	It is known to express the antigen Kx on red blood cells (RBCs) and support the expression of Kell protein antigens.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", ...
PMC7153288	There were three gene clusters for two terpenes and one bacteriocin in the genome of Streptomyces sp. SS1-1 which had no match with known gene clusters for secondary metabolites in bacteria and fungi in the database of the AntiSMASH program (Table 2).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Methods: We performed a computerized search of MEDLINE (PubMed version) from May 1948 through October 2021 using the keywords combinations “(neutropenia or neutropenic) endocarditis” and “endocarditis leukemia”.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11515150	Therefore, we screened the VHHs specially binding to membrane-proximal domain of CD5, followed by constructing CD5 CAR-NK cells in order to expect stronger antitumor response.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11680982	To establish the pivotal role of universal neratinib in enhancing the effectiveness of CDK4/6 inhibitor combined with endocrine therapy in HR/HER2-low breast cancer via HER2 pathway inhibition, HER2 was stably knocked down in human HR/HER2-low breast cancer cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8345486	The viability of ovarian cancer cells was significantly disturbed by the C2′ and C8 derivatives, and the N derivatives containing Fe and Cr ions, regardless of the cellular resistance to platinum.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10778532	Multiple studies showed that the VHL pathway targets also ZHX2 .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Multiple", "studies", "showed", "that", "the", "VHL", "pathway", "targets", "also", "ZHX2", ...
PMC9822769	OCT2 is believed to be responsible for the nephrotoxicity induced by cisplatin.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "OCT2", "is", "believed", "to", "be", "responsible", "for", "the", "nephrotoxicit...
PMC11703992	The membranes were incubated with specific primary antibodies, and followed by incubation of the appropriate peroxidase-conjugated secondary antibodies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "membranes", "were", "incub...
PMC11334037	We used GraphPad Prism 7.0 for data analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "used", "GraphPad", "Prism", "7.0", "for", "data", "analysis", "." ] } ]
PMC11756514	These results are not consistent with previously published results (17, 22) since we observed only an indication of WTA-dependent langerin binding and suggest that langerin binds to an additional S. aureus ligand.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10582049	The algorithm implements linear support vector regression to calculate the relative levels of cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "algorithm", "implements", "linear", "support", "vector", "regre...
PMC11352311	Zhang et al. verified that acteoside, an active ingredient in a natural product, can have a potential therapeutic effect on diabetic kidney disease by targeting the NF-κB pathway, using tools of network pharmacology such as Chinese medicine databases and molecular docking .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Methods: Market research study supported by qualitative interviews with 4 hematologists key opinion leaders (KOL’s).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Methods", ":", "Market", "researc...
PMC9429973	L. Lopes, M. Nucci, R. Portugal Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil Background: The combination of an anthracycline and cytosine arabinoside has been the standard induction therapy in adults with acute myeloid leukemia (AML).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Cell density and viability were assessed, for 72 hours, by trypan blue assay.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cell", "density", "and", "viability", "were", "assessed", "...
PMC9503541	In the first purification, six fractions showed high bioactivity (% cytotoxicity ≥ 50%) at 10 µg/mL in the MTS assay when compared to positive control docetaxel.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11786600	Composite image of area changes of diabetic wound healing. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Composite", "image", "of", "area", "changes", "of", "diabetic", "wound", "healing", ".", "...
PMC8270637	n = 3, P<0.05, P<0.01, **P < 0.001 vs. control group; P < 0.05, P < 0.01, P < 0.001 vs. control group.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10073922	Briefly, 48 hr after transfection, A549 cells (5×10) were suspended with a serum-free medium, kept serum starved for 24 hr, transferred to the upper part of the transwell, and incubated at 37°C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11723947	S1a–c).	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "S1a", "–", "c", ")", "." ] } ]
PMC11762280	P < 0.001.	[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "P", "<", "0.001", "." ] } ]
PMC10723784	Sensitive A2780 cells and resistant A2780/CP70 carcinoma cells and non‐carcinoma cells were exposed to varying concentrations of CBD, CBG, carboplatin or CB1 and CB2 receptor antagonists, AM251 and AM630, respectively, alone or in combination, at different exposure times and cytotoxicity was measured by MTT assay.	[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC11098378	VSV-M51R-eGFP was obtained from Dr. Doug Lyles (Wake Forest University).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "VSV-M51R-eGFP", "was", "obtained", "from", "Dr.", "Doug", "Lyles", "(", "Wake", ...
PMC11789597	D and E) NK‐92 cells were co‐cultured with MM cells expressing shNC or shCAV1 at the indicated ratio for 12 h, and the apoptotic (Annexin V) cells were determined using flow cytometry.	[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11626627	Expression differences of TWIST1 in cancer and adjacent tissues in TCGA-KIRC. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Expression", "differences", "of", "TWIST1", "in", "cancer", "and", "adjacent", "...
PMC11657695	The seven other genes are poorly expressed in most tumour derived cell lines, including ES cell lines (Figures S3A-S3G).Fig.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "seven", "o...
PMC11787355	The surgery was conducted under anesthesia (Ketamin, 100 mg/kg i.p.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "surgery", "was", "conducted", "under", "anesthesia", "(", "Ketamin", ",",...
PMC10631132	No differences in RANK expression could be observed between either differentiation protocol Undifferentiated iPSCs, used as negative control (Fig. 4A and D), displayed a CD34 subpopulation that was larger in the PBMC-derived iPSC line compared to the fibroblast-derived iPSC line.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11697065	Cellular adaptations to these conditions include differential gene expression profiles that can in turn influence the productivity and quality control of recombinant proteins.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cellula...
PMC8633974	TatDE rLNP showed a narrower size distribution with a PDI of 0.045 and an average diameter of 76.11 nm. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "TatDE", "rLNP", "showed", ...
PMC11704834	First, gefitinib treatment induced cytoplasmic relocalization of nuclear TLE1 in part via activation of the cell death Bit1 pathway resulting in inhibition of its gene transcriptional silencing function.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11626627	Xingyu He: Supervision, Conceptualization.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Xingyu", "He", ":", "Supervision", ",", "Conceptualization", "." ] } ]
PMC9429973	MM was diagnosed according to the IMWG-2014 criteria.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "MM", "was", "diagnosed", "according", "to", "the", "IMWG-2014", "criteria", "." ] } ]
PMC7709199	In brief, the data were processed in space group I41 (unit-cell parameters a = 142.99, b = 142.99, c = 139.32 Å) and the structure was solved by maximum-likelihood molecular replacement (MR) in Phaser using the crystal structures of CSF-1 (PDB entry 3uf2; Elegheert et al., 2012 ▸) and CSF-1RD1–D3 as found in the hIL-34...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11224020	Right, average time spent by each cell at their minimum diameter (mean ± s.d.;	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Right", ",", "average", "time", "spent", "b...
PMC11371747	Relative mRNA expression of PCFT and RFC in different types of human cancer cell lines. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Relative", "mRNA", "expression", "of", "PCFT", "and", ...
PMC11777207	For Flt3L-matured BMDCs, bone marrow cells were plated at a concentration of 1 × 10 cells/ml in a 10-cm dish, cultured with Flt3L (50 ng/ml, Peprotech), and topped off with 10 ml of Flt3L (100 ng/ml) at day 3.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8345486	Compound 23 (40 μM) reduced the viability of the adherent cells by about half (A2780, A2780cis, and A2780cisR lines) or by 75% (in SKOV-3), regardless of platinum sensitivity/resistance of the cell line, whereas these cells became resistant to compound 23 when grown in spheroids (Table 2).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "B-CellLine", "O", "O"...
PMC9429973	Results: Twenty outpatient treatments of HD-MTX with glucarpidase were administered to a total of 7 patients (men=3, women=4).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", ":...
PMC9429973	Three/10 patients had a grade ≥ III acute GvHD; all of them are alive and off immunosuppressive therapy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Three/10", "patients", "had", "a"...
PMC9105697	Following hybridization and PCR, 16 and 9 cycles, post-capture samples were size selected using AMPure XP beads (Beckman Coulter, Brea, CA, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9918897	The absorbance was measured at λ = 593 nm; results were expressed based on calibration with ascorbic acid (mg ascorbic acid equivalents/liter beer, calibration range: 0–1250 mg ascorbic acid/liter).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11532793	This is the standard variance function for a quasi-negative-binomial generalized linear model, with ϕt as the NB-dispersion parameter and as the quasi-dispersion.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", ...
PMC11240571	Melanoma cells are considered to release exosomal PD-L1 into the tumor microenvironment and circulation to battle anti-tumor immunity systemically .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Melanoma", "cells", "are", "consi...
PMC8609870	Long noncoding RNA CASC2 can reduce the apoptosis of lung epithelial cells and improve acute lung injury by regulating the miR-144-3p/AQP1 axis .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11711063	Fold changes in phosphorylation normalized to total amounts of kinases are shown in heatmaps. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fold", "changes", "in", "phosphorylation", "normalized", "to", ...
PMC11361748	Scale bars: 50 μm. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bars", ":", "50", "μm", ".", "(" ] } ]
PMC9429973	Image: Summary/Conclusion: Preliminary results of our study confirm that PB CD34+ cells are increased in the majority of MF pts, both at diagnosis and during follow-up.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Image: Summary/Conclusion: V114 was well tolerated in allo-HCT recipients with a generally comparable safety profile to PCV13 for both pediatric and adult participants.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9046263	In addition, IDH mutant GBM patients had relatively lower ERVK3-1 expression; given that HERV expression is closely linked to epigenetic dysregulation, the high degree of methylation seen in IDHm GBM may explain this finding.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6835428	FR-targeted particles displayed only a somewhat reduced liver localization compared to FR-non-targeted particles (38% and 53% of normalized injected dose per gram, respectively).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7348793	In cases where this approach did not result in the closing of the gap, the PCR fragments were cloned in pBluescriptII SK+ and sequenced as part of a plasmid.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9024365	After incubation, coverslips were fixed and imaged.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "incubation", ",", "coverslips", "were", "fixed", "and", "imaged", "." ] } ]
PMC11799620	In addition, temperatures up to 80°C, these elements level rise significantly.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "addition", ",", "temperatures", "up", "to", "80", ...
PMC11635519	Here, we present a high-throughput technology for screening GPCR-activating peptides using a PPI approach.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Here", ",", "we", "present", "a", "high-throughput", "techn...
PMC11763764	The inhibition or silencing of FGFR4 was shown to suppress tumor progression in preclinical ovarian cancer models in vitro and in vivo .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "inhib...
PMC11705547	Cisplatin treatment of tumor cells produces type I IFN, which upregulates costimulatory molecules on APCs and promotes the activation of CTLs.(3) cisplatin potentially induces the differentiation of MDSCs into DCs by increasing the expression of DC markers such as CD40, CD80, and CD86.(4) cisplatin promotes exosome sec...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9895440	Several studies have demonstrated that CAR T cells with a CD28 costimulatory domain release higher quantities of cytokines that may result in adverse effects.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11473750	Comparison of RNF121 mRNA expression in patient subgroups segregated by age at diagnosis, INSS disease stage and MYCN amplification status, indicated that higher RNF121 expression associated with those subgroups with the poorest clinical outcomes (>18 months of age at diagnosis, Stage 4 disease and MYCN amplification) ...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11365983	C,D) The mean Pdgfrα signal intensity in the forebrain meninges is decreased by 50% (P = 2.6 × 10).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11617590	Specifically, previous research on the Mia PaCa‐2 pancreatic cancer cell line has shown that SFN suppresses the expressions of heat shock protein 90 (Hsp90) and its associated proteins, including Akt, cyclin‐dependent kinase 4 (CDK4), and p53, while stimulating the activity of cysteine aspartase (caspase)‐3 to exhibit ...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...

PMC11718274

Consistency with ROS generation results, biochemical measurement of oxidative stress markers demonstrated remarkable induction of oxidative stress within A-431 cancer cells by Y2O3NPs treatment in a concentration-dependent manner compared to both control and doxorubicin-treated A-431 cancer cells (Table 4).

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PMC11734514

1.53e (NIH).

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PMC7022782

Cells were put in contact for 1 h with unloaded NPs and ICG-NPs1, washed, and fixed with a solution containing 2.5% glutaraldehyde and 2% paraformaldehyde in 0.1 M Na-cacodylate buffer (pH 7.4) for 6 h at 4 °C.

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PMC11617590

GSK‐3β is a serine/threonine kinase that plays a role in the development of pancreatic ductal adenocarcinoma (PDAC) by cell proliferation, survival, invasion, metastasis, and resistance to chemotherapy .

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PMC11673902

This process can be divided into two steps: First, water molecules penetrate the bilayer to form an unstable hydrophobic pore, and then the polar head groups of adjacent lipids are redirected toward these water molecules to form a stable hydrophilic pore, allowing polar molecules to enter the cell .

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PMC11407042

Avoid doing this in 96-well plates, as it may damage cells and cause LDH release.

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PMC11742047

Data in the column bar represent the mean ± SD of three different experiments done in triplicate.

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PMC11750165

In wild-type zebrafish embryos, the neural progenitors in the p3 domain divide into two between 9-hpf and 16-hpf; one becomes KA” neuron, whereas the other should remain as a progenitor for next stage of neurogenesis.

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PMC9985266

Then, the sample was sliced into 5-µm-thick paraffin sections after dehydration and embedding.

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PMC11476106

The cytoplasm was generally thin, with limited intercellular spaces, and minimal eosinophilic material (Figure 3E–H).

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PMC9429973

It also may have been impacted by the COVID-19 pandemic.

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PMC9693627

ImageJ software (NIH, Bethesda, MD, USA) was used for quantification.

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PMC7185206

Additional analyses across the TCGA dataset are reported in Supplemental Figure 1 and Supplemental Tables 1–2.

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PMC9429973

TRAD::MYC translocation confers aberrant MYC expression and hyperproliferative of tumor cells.

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PMC8956657

CoIP’s were repeated twice for IMPα1 and α5 and three times for IMPα3.

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PMC10142392

The authors then performed a deprotection of the tert-butyl group from the PCL-µ-PtBA copolymer, and their studies showed a flat and smooth surface, which was due to the good miscibility of PCL and PAA segments.

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PMC11462673

B Western blotting analysis showed that MYB, PARP and GAPDH protein pression in 6 T-CEM and J.gamma1 cells after the effects of MBZ.

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PMC10890055

Continuous cell lines represent an unlimited cell source for testing, since they can proliferate indefinitely.

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PMC11592008

All cell lines had similar mRNA expression levels of PYCARD (Figure 1E).

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PMC11727062

In another study, the combined effect of evodiamine and vemurafenib on A375 cells was investigated.

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PMC10671321

Interaction of ColQ with this complex is necessary for the synaptic localization of ColQ, since LRP4 and MuSK are strictly expressed at the post-synaptic membrane, but two heparin binding sites located in ColQ collagen domain are also indispensable for anchorage of the enzyme in the synaptic basal lamina .

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PMC9739791

JC-1 assay, which allows determination of how mitochondria membrane potential is changed upon exposure to the drug, demonstrated a significant loss of mitochondrial membrane integrity when cells with the Pt(IV) prodrug 27 were irradiated, while the almost negligible effect was observed when cells were treated with the ...

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PMC8806312

The formula for the risk score of every OS patient was constructed: risk score = [CD79A * (−1.926)] + [CSF3R *(−1.4990)] + [MTNR1B *(2.3731)] + [NPPC * (1.1894)].

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PMC11750165

T7E1 assay showed that multiple bands in two out of four embryos.

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PMC8557138

Further, a few studies have highlighted the prospective of electrical stimulation in promoting angiogenesis, however, most of these studies are preliminary in vitro studies, for instance, basic alignment studies under directional electrical fields of 150–400 mV/mm for different cell types like pulmonary artery fibrobla...

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PMC10758402

Subsequently, these cells were infected with HSV.n212 that was genetically modified to express green fluorescent protein, at a low multiplicity of infection (MOI), as shown in ( Figure 1A ).

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PMC11633763

After washing, the beads were resuspended in 20 μL of IP buffer, followed by the addition of protein buffer and boiling for 10 min.

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PMC9352806

YA: young adult. (

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PMC9429973

Other COVID19 strains were very unlikely to be present given the low prevalence in Victoria during the period of study.

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PMC9429973

We studied population-based outcomes in CMML using the NCDB from 2004-2017.

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PMC11365427

During phenylalanine deprivation in MM cells, ATF3 expression was stimulated.

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PMC11467964

Meanwhile, a box plot comparing infiltration levels of the human immune cells was generated (Figure 3B).

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PMC9164404

Specifically, in the Abplatin treated group, twenty phosphatidylcholine (PCs), three phosphatidylglycerols (PGs), four lysophosphatidylcholines (LPCs), one lysophosphatidylethanolamine (LPE), one sphingomyelin (SM) and two lysosphingomyelins (LSMs) were up-regulated compared with the PBS treatment group.

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PMC11772585

Among these modifications, N7-methylguanosine (m7G) modification was identified as a prevalent posttranscriptional RNA modification that affects tRNAs, rRNAs, miRNAs, as well as mRNAs, playing critical roles in RNA processing, metabolism, and functions .

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PMC5941560

Overlaps between duplication and inversion calls were determined less stringently.

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PMC9919300

The hepatoprotective activity of curcumin is controversial, with reported cases of hepatotoxicity with curcumin dietary supplementation, which lead the Italian Health Ministry to discourage its administration in subjects with liver function alterations.

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PMC11476264

It is often accompanied by metastases in late stages .

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PMC10936243

the welfare, just that sometimes, they’ve been dragging with too much workload and everything, and then they want everything to work fast.

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PMC11371627

It is known to express the antigen Kx on red blood cells (RBCs) and support the expression of Kell protein antigens.

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PMC7153288

There were three gene clusters for two terpenes and one bacteriocin in the genome of Streptomyces sp. SS1-1 which had no match with known gene clusters for secondary metabolites in bacteria and fungi in the database of the AntiSMASH program (Table 2).

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PMC9429973

Methods: We performed a computerized search of MEDLINE (PubMed version) from May 1948 through October 2021 using the keywords combinations “(neutropenia or neutropenic) endocarditis” and “endocarditis leukemia”.

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PMC11515150

Therefore, we screened the VHHs specially binding to membrane-proximal domain of CD5, followed by constructing CD5 CAR-NK cells in order to expect stronger antitumor response.

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PMC11680982

To establish the pivotal role of universal neratinib in enhancing the effectiveness of CDK4/6 inhibitor combined with endocrine therapy in HR/HER2-low breast cancer via HER2 pathway inhibition, HER2 was stably knocked down in human HR/HER2-low breast cancer cells.

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PMC8345486

The viability of ovarian cancer cells was significantly disturbed by the C2′ and C8 derivatives, and the N derivatives containing Fe and Cr ions, regardless of the cellular resistance to platinum.

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PMC10778532

Multiple studies showed that the VHL pathway targets also ZHX2 .

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PMC9822769

OCT2 is believed to be responsible for the nephrotoxicity induced by cisplatin.

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PMC11703992

The membranes were incubated with specific primary antibodies, and followed by incubation of the appropriate peroxidase-conjugated secondary antibodies.

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PMC11334037

We used GraphPad Prism 7.0 for data analysis.

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PMC11756514

These results are not consistent with previously published results (17, 22) since we observed only an indication of WTA-dependent langerin binding and suggest that langerin binds to an additional S. aureus ligand.

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PMC10582049

The algorithm implements linear support vector regression to calculate the relative levels of cells.

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PMC11352311

Zhang et al. verified that acteoside, an active ingredient in a natural product, can have a potential therapeutic effect on diabetic kidney disease by targeting the NF-κB pathway, using tools of network pharmacology such as Chinese medicine databases and molecular docking .

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PMC9429973

Methods: Market research study supported by qualitative interviews with 4 hematologists key opinion leaders (KOL’s).

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PMC9429973

L. Lopes, M. Nucci, R. Portugal Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil Background: The combination of an anthracycline and cytosine arabinoside has been the standard induction therapy in adults with acute myeloid leukemia (AML).

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PMC9429973

Cell density and viability were assessed, for 72 hours, by trypan blue assay.

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PMC9503541

In the first purification, six fractions showed high bioactivity (% cytotoxicity ≥ 50%) at 10 µg/mL in the MTS assay when compared to positive control docetaxel.

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PMC11786600

Composite image of area changes of diabetic wound healing. (

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PMC8270637

n = 3, *P<0.05, **P<0.01, ***P < 0.001 vs. control group; P < 0.05, P < 0.01, P < 0.001 vs. control group.

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PMC10073922

Briefly, 48 hr after transfection, A549 cells (5×10) were suspended with a serum-free medium, kept serum starved for 24 hr, transferred to the upper part of the transwell, and incubated at 37°C.

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PMC11723947

S1a–c).

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PMC11762280

P < 0.001.

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PMC10723784

Sensitive A2780 cells and resistant A2780/CP70 carcinoma cells and non‐carcinoma cells were exposed to varying concentrations of CBD, CBG, carboplatin or CB1 and CB2 receptor antagonists, AM251 and AM630, respectively, alone or in combination, at different exposure times and cytotoxicity was measured by MTT assay.

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PMC11098378

VSV-M51R-eGFP was obtained from Dr. Doug Lyles (Wake Forest University).

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PMC11789597

D and E) NK‐92 cells were co‐cultured with MM cells expressing shNC or shCAV1 at the indicated ratio for 12 h, and the apoptotic (Annexin V) cells were determined using flow cytometry.

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PMC11626627

Expression differences of TWIST1 in cancer and adjacent tissues in TCGA-KIRC. (

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PMC11657695

The seven other genes are poorly expressed in most tumour derived cell lines, including ES cell lines (Figures S3A-S3G).Fig.

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PMC11787355

The surgery was conducted under anesthesia (Ketamin, 100 mg/kg i.p.

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PMC10631132

No differences in RANK expression could be observed between either differentiation protocol Undifferentiated iPSCs, used as negative control (Fig. 4A and D), displayed a CD34 subpopulation that was larger in the PBMC-derived iPSC line compared to the fibroblast-derived iPSC line.

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PMC11697065

Cellular adaptations to these conditions include differential gene expression profiles that can in turn influence the productivity and quality control of recombinant proteins.

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PMC8633974

TatDE rLNP showed a narrower size distribution with a PDI of 0.045 and an average diameter of 76.11 nm. (

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PMC11704834

First, gefitinib treatment induced cytoplasmic relocalization of nuclear TLE1 in part via activation of the cell death Bit1 pathway resulting in inhibition of its gene transcriptional silencing function.

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PMC11626627

Xingyu He: Supervision, Conceptualization.

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PMC9429973

MM was diagnosed according to the IMWG-2014 criteria.

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PMC7709199

In brief, the data were processed in space group I41 (unit-cell parameters a = 142.99, b = 142.99, c = 139.32 Å) and the structure was solved by maximum-likelihood molecular replacement (MR) in Phaser using the crystal structures of CSF-1 (PDB entry 3uf2; Elegheert et al., 2012 ▸) and CSF-1RD1–D3 as found in the hIL-34...

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PMC11224020

Right, average time spent by each cell at their minimum diameter (mean ± s.d.;

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PMC11371747

Relative mRNA expression of PCFT and RFC in different types of human cancer cell lines. (

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PMC11777207

For Flt3L-matured BMDCs, bone marrow cells were plated at a concentration of 1 × 10 cells/ml in a 10-cm dish, cultured with Flt3L (50 ng/ml, Peprotech), and topped off with 10 ml of Flt3L (100 ng/ml) at day 3.

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PMC8345486

Compound 23 (40 μM) reduced the viability of the adherent cells by about half (A2780, A2780cis, and A2780cisR lines) or by 75% (in SKOV-3), regardless of platinum sensitivity/resistance of the cell line, whereas these cells became resistant to compound 23 when grown in spheroids (Table 2).

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PMC9429973

Results: Twenty outpatient treatments of HD-MTX with glucarpidase were administered to a total of 7 patients (men=3, women=4).

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PMC9429973

Three/10 patients had a grade ≥ III acute GvHD; all of them are alive and off immunosuppressive therapy.

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PMC9105697

Following hybridization and PCR, 16 and 9 cycles, post-capture samples were size selected using AMPure XP beads (Beckman Coulter, Brea, CA, USA).

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PMC9918897

The absorbance was measured at λ = 593 nm; results were expressed based on calibration with ascorbic acid (mg ascorbic acid equivalents/liter beer, calibration range: 0–1250 mg ascorbic acid/liter).

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PMC11532793

This is the standard variance function for a quasi-negative-binomial generalized linear model, with ϕt as the NB-dispersion parameter and as the quasi-dispersion.

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PMC11240571

Melanoma cells are considered to release exosomal PD-L1 into the tumor microenvironment and circulation to battle anti-tumor immunity systemically .

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PMC8609870

Long noncoding RNA CASC2 can reduce the apoptosis of lung epithelial cells and improve acute lung injury by regulating the miR-144-3p/AQP1 axis .

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PMC11711063

Fold changes in phosphorylation normalized to total amounts of kinases are shown in heatmaps. (

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PMC11361748

Scale bars: 50 μm. (

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PMC9429973

Image: Summary/Conclusion: Preliminary results of our study confirm that PB CD34+ cells are increased in the majority of MF pts, both at diagnosis and during follow-up.

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PMC9429973

Image: Summary/Conclusion: V114 was well tolerated in allo-HCT recipients with a generally comparable safety profile to PCV13 for both pediatric and adult participants.

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PMC9046263

In addition, IDH mutant GBM patients had relatively lower ERVK3-1 expression; given that HERV expression is closely linked to epigenetic dysregulation, the high degree of methylation seen in IDHm GBM may explain this finding.

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PMC6835428

FR-targeted particles displayed only a somewhat reduced liver localization compared to FR-non-targeted particles (38% and 53% of normalized injected dose per gram, respectively).

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PMC7348793

In cases where this approach did not result in the closing of the gap, the PCR fragments were cloned in pBluescriptII SK+ and sequenced as part of a plasmid.

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PMC9024365

After incubation, coverslips were fixed and imaged.

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PMC11799620

In addition, temperatures up to 80°C, these elements level rise significantly.

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PMC11635519

Here, we present a high-throughput technology for screening GPCR-activating peptides using a PPI approach.

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PMC11763764

The inhibition or silencing of FGFR4 was shown to suppress tumor progression in preclinical ovarian cancer models in vitro and in vivo .

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PMC11705547

Cisplatin treatment of tumor cells produces type I IFN, which upregulates costimulatory molecules on APCs and promotes the activation of CTLs.(3) cisplatin potentially induces the differentiation of MDSCs into DCs by increasing the expression of DC markers such as CD40, CD80, and CD86.(4) cisplatin promotes exosome sec...

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PMC9895440

Several studies have demonstrated that CAR T cells with a CD28 costimulatory domain release higher quantities of cytokines that may result in adverse effects.

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PMC11473750

Comparison of RNF121 mRNA expression in patient subgroups segregated by age at diagnosis, INSS disease stage and MYCN amplification status, indicated that higher RNF121 expression associated with those subgroups with the poorest clinical outcomes (>18 months of age at diagnosis, Stage 4 disease and MYCN amplification) ...

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PMC11365983

C,D) The mean Pdgfrα signal intensity in the forebrain meninges is decreased by 50% (P = 2.6 × 10).

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PMC11617590

Specifically, previous research on the Mia PaCa‐2 pancreatic cancer cell line has shown that SFN suppresses the expressions of heat shock protein 90 (Hsp90) and its associated proteins, including Akt, cyclin‐dependent kinase 4 (CDK4), and p53, while stimulating the activity of cysteine aspartase (caspase)‐3 to exhibit ...

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