OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC7709199	A less drastic truncation of the N-linked glycans could be achieved by expressing the CSF-1RD1–D3 glycosylation mutants in the GlycoDelete cell line.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "less", ...
PMC11543853	The precipitation was allowed to proceed at 10 °C with mild shaking (80 RPM) for 12 h. The following day, the precipitate was pelleted at 15,000× g in a Beckman Coulter Allegra 25 R centrifuge, TA-10 rotor at 10 °C for 30 min.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11380454	In addition to enhanced chemosensitivity induced by both the inhibition of IL-10 and PD-L1, the suppression of IL-10 by tellurium compounds may lead to a switch in immune responses from Th2 responses to Th1 responses 25, 27.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	F. Haddad, H. Kantarjian, E. Jabbour, N. Short, A. Bidikian, J. Ning, L. Xiao, N. Pemmaraju, K. Marx, F. Ravandi, K. Sasaki, G. Issa Leukemia; Statistics, The University of Texas MD Anderson Cancer Center, Houston, United States of America Background: Bariatric surgery is widely used in patients (pts) with morbid obesi...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10669128	Then, they implanted PDXs of various cancers (sarcoma, non-small cell lung cancer, bladder, triple-negative breast cancer) into HuNGSs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC4005030	The results proved that Alpinia PCA significantly elevated the splenic weights, increased the activities of glutathione peroxidase and catalase, and decreased the malondialdehyde level of aged rats.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11736898	Migration was increased in normal keratinocytes treated with vitamin D alone compared with untreated cells, but this difference was not statistically significant (Figure 6a).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10669966	SHANK2 and CTAG2 emerged in the MLPS-specific list and AXL emerged in the PLPS-specific list; these genes have previously been described as upregulated in these subtypes .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6337547	Furthermore, it attenuates the activation of p38, ERK, integrin αIIbβ3, and JNK.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Furthermore", ",", "it", "attenuates", "the", "activat...
PMC11574029	D, E Cell proliferation assessed by CCK8 assay.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "D", ",", "E", "Cell", "proliferation", "assessed", "by", "CCK8", "assay", "." ] } ]
PMC11678130	However, the ability of QUE to sensitize tumor cells to 5-FU has been well documented in previous studies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "the", "ability", ...
PMC9429973	aaIPI was high (≥2) in 27 cases (41%).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "aaIPI", "was", "high", "(", "≥2", ")", "in", "27", "cases", "("...
PMC11522251	For individuals with colorectal cancer, the BRAF V600E mutation is an indicator of a bad prognosis , and by circulating tumor DNA (ctDNA) research, the BRAF mutation has also been introduced as a cause of the first-time anti-EGFR mechanism of acquired resistance in patients responding to treatment .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11271278	This analysis identified previously reported trans-enhancer hijacking events activating oncogenes CCND1 in the B-cell lymphoma cell line REC1 and ETV1 in the prostate cancer cell lines LNCaP and MDAPCA2B.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11406030	To demonstrate the specificity of LMTK3 as a target, we utilized LMTK3-specific siRNA; silencing LMTK3 gene expression led to a dose-dependent decrease in cell viability in all ovarian cancer cell lines tested but not in normal epithelial ovarian cells (Figure 3A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC2193049	The mass determination was based on the mass-to-charge (m/z) ratio.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "mass", "determination", "was", "based", "on", "the", "mass-to-charge", "(...
PMC9512971	Safety evaluations included monitoring of adverse events, laboratory tests, vital signs, and 12-lead electrocardiography throughout the study.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Safety", "evaluations", "inc...
PMC8170755	This event, along with elevated caspase-3 activity, can finally result in apoptosis in A549 human lung cancer cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O" ], "tokens": [ "This", "event", ","...
PMC9429973	The study is still ongoing and it is worth looking forward to updating the long-term survival data.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "study", "is", "still", "ongoing", "a...
PMC11321678	ScATAC‐seq subpopulations for WNT, SHH, Group3, and Group4 were annotated based on gene activity score, using canonical marker genes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ScATAC‐...
PMC11470381	Do this for all ROIs corresponding to cell masks in each time frame (Figure 4A, B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Do", "this", "for", "all", ...
PMC11615828	The region of interest (ROI) was then photobleached with 100% 488 nm laser power and allowed to recover for the indicated time.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC7338939	However, its long-term effect is not clear.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "its", "long-term", "effect", "is", "not", "clear", "." ] } ]
PMC11743414	After washing the polyvinylidene difluoride membrane with Tris-buffered saline/Polysorbate 20 3 times (5 min/wash), we incubated the membrane with sheep anti-rabbit secondary antibody at room temperature for 2 h. Then the membrane was washed and developed to detect the protein expression level.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11371627	Females can rarely be affected, generally displaying a milder phenotype (Danek et al., 2001; Roulis et al., 2018).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9884169	In order to verify the relationship between inhibition of autophagy induced by knockdown of MCT4 and apoptosis in 5637 cells, we continued to apply CQ (Selleck) to induce autophagy inhibition in cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", ...
PMC11482552	Additionally, Cocuzza et al. reported the use of CCR5 to determine the number of human cells present in clinical samples, thereby enabling the normalization of viral copy numbers per cell for the accurate quantification of HPV viral loads.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11188874	Cells were also treated with bortezomib (10 nmol/L) for 16 hours.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", "were", "also", "treated", "with", "bortezomib", "(", "10", "...
PMC6450504	The cell detachment solution was inactivated by FBS addition and cells were centrifuged, washed and redispersed in PBS and immediately analyzed by flow cytometry using the settings described earlier.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11635087	Before the imaging, the CHO-K1 cells were fixed with the 4% paraformaldehyde (PFA) for 15 minutes and washed twice with 1 mL of PBS (－).	[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11545737	Pyroptosis plays an essential role in the innate immune response, inhibiting the replication of pathogens in the intracellular environment and activating immune cells to eradicate the infection .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10978090	Results were expressed in optical density (OD) units and values >0.5 were considered positive.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", "were", "expressed", "in", "optical", ...
PMC11653533	The ethanol and methanol extracts from F. benghalensis root showed antioxidant potential, demonstrated by their ability to donate electrons and hydrogen, as well as scavenge radicals.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11392912	We randomly selected four Indian spices (turmeric, fenugreek, kalonji, and flax seed) that are regularly consumed, specifically by the Indian population.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9046263	These findings are summarized in Fig. 5A,B, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "findings", "are", "summarized", "in", "Fig.", "5A", ",", "B", ",", "re...
PMC9275501	Polymeric micelles can selectively and effectively accumulate in tumors by enhancing the permeability and retention (EPR) effect, thus improving the therapeutic effect of chemotherapy drugs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Thirty patient s were treated with cladribine intravenous infusion 0.1 mg/kg per day for 7 days.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thirty", "patient", "s", "were", "treated", "with", ...
PMC11441402	It is important that the techniques used to analyze the effects of compounds on cell proliferation and viability are accurate and reproducible.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "is", ...
PMC11545868	After that, the recruitment and activation of procaspase-9 then initiates the pathway of apoptosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "that", ",", "the", "recruitment", "and", "activati...
PMC8567602	For each of the genotypes that included Smarcb1 homozygous loss, TATCre and Myf5Cre tumors each clustered distinctly but in adjacent groups.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "each"...
PMC10545062	This study demonstrates feasibility of automated critical care to achieve target hemodynamics, while concurrently optimizing multi-modal resuscitation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "study", "demonstrates", "feasibility...
PMC11155445	All these compounds also exhibited low anti-biofilm activity except compound (102g) with an MBIC value of 312 μg mL against E. coli.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11680578	One of the best hallmarks of apoptosis is the condensation followed by fragmentation of the nuclei.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "One", "of", "the", "best", "hallmarks", "of", "a...
PMC4270159	d. Load 16 µl of sample (25–30 µg/lane) in each well of the Tris–glycine gel.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "d.", "Load", "16", "µl", "o...
PMC11320834	Data are shown as the mean ± SD, n = 3.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "are", "shown", "as", "the", "mean", "±", "SD", ",", "n", "="...
PMC9429973	The patients’ history of antiplatelets and anticoagulants was obtained.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "patients", "’", "history", "of", "antiplatelets", "and", "anticoagulants", "was", "obtain...
PMC11269933	In vivo (Figure 5D) and in vitro (Figure 5C) kinase assays, coupled with CgERK1/2 (mimicking phosphorylation) and CgERK1/2 (mimicking dephosphorylation) mutants provided compelling evidence that phosphorylation at CgERK1/2 T187 and Y189 significantly enhanced its kinase activity, causing an elevated phosphorylation lev...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11240448	However, specific distinctions between different cell lines in terms of the connection strengths and feedbacks shape the activity patterns of luminal BC cell signaling networks and, as a result, also influence the cell phenotypes, determined by the DPDonc and DPDL-B scores.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11519583	Furthermore, Ror2 knockdown (KD) inhibited the adipogenic differentiation of MPs, as assessed using Oil Red O staining and differentiation marker profiling (Fig. 1c and Supplementary Fig. 2c).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11796104	By overlapping 607 host genes with 3296 mRNAs acquired in previous study, 222 common genes were obtained.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "By", "overlapping", "607", "host", "ge...
PMC9250505	It was next examined whether the small molecule inhibitor of BADS99 phosphorylation, NPB, synergized with PARP inhibition in EOC cell lines (Fig. 2, Supplementary Fig. 2).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11122631	And, only one value (flexibility) of nine compounds was not located in the ideal zone.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "And", ",", "only", "one", "value", ...
PMC9031474	Compound 35 was shown to be the most active compound.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Compound", "35", "was", "shown", "to", "be", "the", "most", "active", "compound", "." ...
PMC11682172	The effects were significantly less for the cell line derived from breast cancer with affinity for brain.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "effects", "were", "significantly", "less",...
PMC11547917	The IC50 values for DPPH and ABTS were calculated by graphing concentrations of the extract against the proportional antioxidant inhibition percent .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "IC50", "va...
PMC9352806	Synchronized L1 worms were supplemented with ddH2O as control or BMS (100 μg/mL or 200 μg/mL, final concentrations) mixed with E. coli OP50 on NGM plate.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11751675	F., and demonstrated antiviral activity against HIV in C8166 cells with EC50 values of 44.0 and 41.8 μM and SI values of 5.4 and 6.2, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8998437	Notably, each form of EBV-restricted latency in the isolated cellular clones was associated with protection from apoptosis and high c-MYC expression .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Notably", ",...
PMC11733919	The apoptotic morphotype of cell death in treated cells was assayed using Annexin V staining as a marker of apoptosis (phosphatidylserine externalization).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11394386	Cells (100,000 per well) were seeded in 24-well plates and co-transfected with PGL 4.42 and pRL-null vector (Promega, Madison, WI, USA) for normalization.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11055510	The red box is high expression in the tumor, and the gray box is the low expression in the tumor. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "red",...
PMC9512971	A serious adverse event (prinzmetal angina) occurred in one patient in the camostat mesilate group, but it was not considered related to the study drug.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10957991	n for all samples is 3.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "n", "for", "all", "samples", "is", "3", "." ] } ]
PMC10362265	Nonetheless, the human tetramer stayed intact even after the disruption of one of its interfaces, reflecting the sufficiency of one intact interface for tetramer stability.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11515150	NK cells derived from PBMCs were purified via CD3 cells depletion followed by CD56 cells enrichment, and maintained in NK MACS Medium (NK basal medium (Miltenyi Biotec, Bergisch Gladbach, Germany) supplemented with 1% of NK MACS Supplement, 5% CTS Immune Cell Serum, and combination of 500 IU/mL IL-2 (SI HUAN SHENG WU, ...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7171147	Given our initial observation that FAO is upregulated in cisplatin-resistant variant of A2780 cell line (A2780cis), we sought to test whether FAO inhibition can attenuate COL11A1-induced cisplatin resistance in ovarian cancer cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC9429973	MSI2 enhancers located in intronic regions were strongly activated in SOX11+ but not in SOX11- MCL cell lines and primary cases.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "MSI2", "enha...
PMC9429973	Cell viability assay and colony-forming unit assay were used to examine the response of GFI1-36S and GFI1-36N leukemic cells to palbociclib treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11604830	More in detail, the PFCE‐NE accumulation was observed specifically in the right PLN, corresponding to the tumor location.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "More", "in", "detail", ...
PMC11488203	Together, these findings demonstrate growth-reducing effects of different miRs on distinct cancer cell lines suggesting potentially selective miR effects on certain tumor entities.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC7757104	The MTT assay (Uniscience Corp.) was used to measure the cytotoxic effects of CDDP (Libbs Farmaceutica, Ltda.)	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "MTT",...
PMC10788478	LGR6 overexpression confers the in vitro tumor growth and spheroid formation abilities in lung cancer cell lines. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "LGR6", "overexpression", "confers", "the", ...
PMC7039683	However, robust chromatin mark evidence from human embryonic faces and human epidermal keratinocytes suggests the lack ennhancer activity of these elements in the zebrafish and mouse embryo assays reflects a technical artifact; for instance it is possible these enhancers are not compatible with the basal promoter in th...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC2777936	Expression of FZD5, FZD7, WNT5A, and POU5F1 in human germ cell tumor cell lines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Expression", "of", "FZD5", ",", "FZD7", ","...
PMC9429973	Aims: To identify the frequency, specificity and clinical significance of MIR-34B/C, MIR-34A, MIR-203 and MIR-129-2 genes methylation in Diffuse Large B-cell Lymphoma (DLBCL).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7840816	None of these patients received chemotherapy or radiotherapy before surgery, and informed consent was obtained from each patient before surgery.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "None", "of", "the...
PMC11711063	Bex + Carv also reduced ZG16B levels in vivo in normal breast tissue and MDA‐MB231 tumor xenografts.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O" ], "tokens": [ "Bex", "+", "Carv", "also", "reduced", ...
PMC9429973	Nevertheless, infection and thrombosis are two of the main complications associated with their use, but their rates and risk factors are highly variable.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC8740518	Further, down-regulation was observed for amino acids, especially isoleucine, which is consistent with up-regulation of amino acid transporter genes SLC7A5 and SLC1A3 in MM.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The proportion of pts with SVR35 was greater among those who initiated RUX earlier (≤12 mo vs >12 mo) at Wk 24 (48% vs 33%; P=0.0610) and 48 (44% vs 27%; P=0.0149; Table).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	This effect was more pronounced after repeated cytarabine treatment, leading to increased proliferation of LICs and augmented leukaemia burden at relapse.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "effe...
PMC11783017	As shown in Fig. 4O, the Cis/Mn/NH@PGP treatment significantly upregulated the phosphorylation of STING, TANK binding kinase 1 (TBK1), and interferon regulatory factor 3 (IRF3) in DCs, indicating the activation of the STING pathway.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11484188	miRNA mimic and inhibitor were transfected into 293T (China Center for Type Culture Collection), U266 and RPMI-8266 cells using Lipofectamine 2000 reagent (Invitrogen; Thermo Fisher Scientific, Inc.) according to the manufacturer's protocol.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", ...
PMC8735881	Transduced human primary CD4 T cells were infected with 1,000 TCID50 of NL4-3, and intracellular p24 and GFP expression were monitored over time by flow cytometry.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11767793	In this report, we present data on the cellular viability and corresponding particle characterization obtained with eight different cell lines that were exposed to Au-PEI and carboxylate-polyethylene-glycol-conjugated AuNPs (Au-PEG-COOH, as anionic NPs).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7369657	Healthy male BALB/c mice (6–8 weeks, 18–20 g) and male BALB/c nude mice (4–6 weeks, 16–18 g) were purchased from Beijing Vital River Laboratory Animal Technology Co. (Beijing, China).	[ { "tags": [ "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC10850553	Some signals for C5ar1 were co-localized with those for the neutrophil marker, Myeloperoxidase (Fig. 1B, Supplementary Fig. S1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Some", "sign...
PMC11739504	The White dotted line defines the area of the renal tubule.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "White", "dotted", "line", "defines", "the", "area", "of", "the", "renal", ...
PMC11777207	Tailless constructs were made via standard cloning using primers to replace residue 276 with a stop codon so that the CD80 extracellular domain and transmembrane domain remained intact, but the C terminal tail was absent after residue 275.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8913139	miR-101 suppressed the invasion, migration, and proliferation of osteosarcoma cells by downregulating ROCK1 .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "miR-101", "suppressed", "the", "invasion", ",", "migration", ...
PMC11281366	To measure ADCML, cells were treated with the Zombie NIR Fixable Viability marker (1:150 in PBS; Biolegend, #423105) and analyzed via flow cytometry.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10975211	Bioconjugation enhances specificity-controlled release and combats drug resistance, presenting a promising avenue for targeted cancer treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Bioconjugation", "enhances", "specificity-controlled", ...
PMC10932641	The cells of each group in the logarithmic growth phase were digested and centrifuged in routine fashion, and then the cell precipitate was resuspended with PBS to ensure that the concentration of the cell suspension was 3×10/mL. Each 4-week-old nude mouse was inoculated with 0.2 mL of cell suspension into the subcutan...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11731161	The graphic was generated using Biorender.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "graphic", "was", "generated", "using", "Biorender", "." ] } ]
PMC9952933	At 24 h and 48 h after treatment, the malignant cells showed a treatment time-dependent reduction in cell viability.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "At", "24", "h", "and",...
PMC11615101	The bar graph represents the fold change of α-Taxilin expression based on densitometric values of WB after knockdown using 25nM and 50nM Si-RNA induction and 20ng/ml TNF-α induction along with non-specific Si-RNA control. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9587298	Secondly, we evaluated the antiglycation activity of elderberry extracts, applying cell models, Caco-2 and HepG2 cells, with characteristics and morphology of intestinal epithelium and hepatocytes, respectively, two significant barriers against toxic and xenobiotic agents in the organism.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "...
PMC11742431	The degradation of intracellular Survivin protein promoted the apoptosis of 5637 cells and inhibited proliferation and migration.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "degradation", "of", "intracellular", ...
PMC11725127	As depicted in Fig. 4A–D, the knockout of USP2 resulted in a reduction in the KRAS protein levels (Fig. 4A and C) but not in mRNA levels (Fig. 4B and D) in both cell lines, which was similar to the effects of GA treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11514418	Pancreatic cancer has an insidious onset and a high mortality rate, and most patients were diagnosed at an advanced stage, losing the chance for surgical procedures and requiring conservative chemotherapy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC7709199

A less drastic truncation of the N-linked glycans could be achieved by expressing the CSF-1RD1–D3 glycosylation mutants in the GlycoDelete cell line.

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PMC11543853

The precipitation was allowed to proceed at 10 °C with mild shaking (80 RPM) for 12 h. The following day, the precipitate was pelleted at 15,000× g in a Beckman Coulter Allegra 25 R centrifuge, TA-10 rotor at 10 °C for 30 min.

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PMC11380454

In addition to enhanced chemosensitivity induced by both the inhibition of IL-10 and PD-L1, the suppression of IL-10 by tellurium compounds may lead to a switch in immune responses from Th2 responses to Th1 responses 25, 27.

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PMC9429973

F. Haddad, H. Kantarjian, E. Jabbour, N. Short, A. Bidikian, J. Ning, L. Xiao, N. Pemmaraju, K. Marx, F. Ravandi, K. Sasaki, G. Issa Leukemia; Statistics, The University of Texas MD Anderson Cancer Center, Houston, United States of America Background: Bariatric surgery is widely used in patients (pts) with morbid obesi...

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PMC10669128

Then, they implanted PDXs of various cancers (sarcoma, non-small cell lung cancer, bladder, triple-negative breast cancer) into HuNGSs.

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PMC4005030

The results proved that Alpinia PCA significantly elevated the splenic weights, increased the activities of glutathione peroxidase and catalase, and decreased the malondialdehyde level of aged rats.

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PMC11736898

Migration was increased in normal keratinocytes treated with vitamin D alone compared with untreated cells, but this difference was not statistically significant (Figure 6a).

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PMC10669966

SHANK2 and CTAG2 emerged in the MLPS-specific list and AXL emerged in the PLPS-specific list; these genes have previously been described as upregulated in these subtypes .

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PMC6337547

Furthermore, it attenuates the activation of p38, ERK, integrin αIIbβ3, and JNK.

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PMC11574029

D, E Cell proliferation assessed by CCK8 assay.

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PMC11678130

However, the ability of QUE to sensitize tumor cells to 5-FU has been well documented in previous studies.

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PMC9429973

aaIPI was high (≥2) in 27 cases (41%).

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PMC11522251

For individuals with colorectal cancer, the BRAF V600E mutation is an indicator of a bad prognosis , and by circulating tumor DNA (ctDNA) research, the BRAF mutation has also been introduced as a cause of the first-time anti-EGFR mechanism of acquired resistance in patients responding to treatment .

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PMC11271278

This analysis identified previously reported trans-enhancer hijacking events activating oncogenes CCND1 in the B-cell lymphoma cell line REC1 and ETV1 in the prostate cancer cell lines LNCaP and MDAPCA2B.

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PMC11406030

To demonstrate the specificity of LMTK3 as a target, we utilized LMTK3-specific siRNA; silencing LMTK3 gene expression led to a dose-dependent decrease in cell viability in all ovarian cancer cell lines tested but not in normal epithelial ovarian cells (Figure 3A).

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PMC2193049

The mass determination was based on the mass-to-charge (m/z) ratio.

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PMC9512971

Safety evaluations included monitoring of adverse events, laboratory tests, vital signs, and 12-lead electrocardiography throughout the study.

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PMC8170755

This event, along with elevated caspase-3 activity, can finally result in apoptosis in A549 human lung cancer cells.

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PMC9429973

The study is still ongoing and it is worth looking forward to updating the long-term survival data.

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PMC11321678

ScATAC‐seq subpopulations for WNT, SHH, Group3, and Group4 were annotated based on gene activity score, using canonical marker genes.

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PMC11470381

Do this for all ROIs corresponding to cell masks in each time frame (Figure 4A, B).

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PMC11615828

The region of interest (ROI) was then photobleached with 100% 488 nm laser power and allowed to recover for the indicated time.

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PMC7338939

However, its long-term effect is not clear.

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PMC11743414

After washing the polyvinylidene difluoride membrane with Tris-buffered saline/Polysorbate 20 3 times (5 min/wash), we incubated the membrane with sheep anti-rabbit secondary antibody at room temperature for 2 h. Then the membrane was washed and developed to detect the protein expression level.

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PMC11371627

Females can rarely be affected, generally displaying a milder phenotype (Danek et al., 2001; Roulis et al., 2018).

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PMC9884169

In order to verify the relationship between inhibition of autophagy induced by knockdown of MCT4 and apoptosis in 5637 cells, we continued to apply CQ (Selleck) to induce autophagy inhibition in cells.

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PMC11482552

Additionally, Cocuzza et al. reported the use of CCR5 to determine the number of human cells present in clinical samples, thereby enabling the normalization of viral copy numbers per cell for the accurate quantification of HPV viral loads.

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PMC11188874

Cells were also treated with bortezomib (10 nmol/L) for 16 hours.

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PMC6450504

The cell detachment solution was inactivated by FBS addition and cells were centrifuged, washed and redispersed in PBS and immediately analyzed by flow cytometry using the settings described earlier.

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PMC11635087

Before the imaging, the CHO-K1 cells were fixed with the 4% paraformaldehyde (PFA) for 15 minutes and washed twice with 1 mL of PBS (－).

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PMC11545737

Pyroptosis plays an essential role in the innate immune response, inhibiting the replication of pathogens in the intracellular environment and activating immune cells to eradicate the infection .

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PMC10978090

Results were expressed in optical density (OD) units and values >0.5 were considered positive.

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PMC11653533

The ethanol and methanol extracts from F. benghalensis root showed antioxidant potential, demonstrated by their ability to donate electrons and hydrogen, as well as scavenge radicals.

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PMC11392912

We randomly selected four Indian spices (turmeric, fenugreek, kalonji, and flax seed) that are regularly consumed, specifically by the Indian population.

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PMC9046263

These findings are summarized in Fig. 5A,B, respectively.

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PMC9275501

Polymeric micelles can selectively and effectively accumulate in tumors by enhancing the permeability and retention (EPR) effect, thus improving the therapeutic effect of chemotherapy drugs.

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PMC9429973

Thirty patient s were treated with cladribine intravenous infusion 0.1 mg/kg per day for 7 days.

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PMC11441402

It is important that the techniques used to analyze the effects of compounds on cell proliferation and viability are accurate and reproducible.

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PMC11545868

After that, the recruitment and activation of procaspase-9 then initiates the pathway of apoptosis.

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PMC8567602

For each of the genotypes that included Smarcb1 homozygous loss, TATCre and Myf5Cre tumors each clustered distinctly but in adjacent groups.

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PMC10545062

This study demonstrates feasibility of automated critical care to achieve target hemodynamics, while concurrently optimizing multi-modal resuscitation.

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PMC11155445

All these compounds also exhibited low anti-biofilm activity except compound (102g) with an MBIC value of 312 μg mL against E. coli.

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PMC11680578

One of the best hallmarks of apoptosis is the condensation followed by fragmentation of the nuclei.

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PMC4270159

d. Load 16 µl of sample (25–30 µg/lane) in each well of the Tris–glycine gel.

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PMC11320834

Data are shown as the mean ± SD, n = 3.

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PMC9429973

The patients’ history of antiplatelets and anticoagulants was obtained.

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PMC11269933

In vivo (Figure 5D) and in vitro (Figure 5C) kinase assays, coupled with CgERK1/2 (mimicking phosphorylation) and CgERK1/2 (mimicking dephosphorylation) mutants provided compelling evidence that phosphorylation at CgERK1/2 T187 and Y189 significantly enhanced its kinase activity, causing an elevated phosphorylation lev...

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PMC11240448

However, specific distinctions between different cell lines in terms of the connection strengths and feedbacks shape the activity patterns of luminal BC cell signaling networks and, as a result, also influence the cell phenotypes, determined by the DPDonc and DPDL-B scores.

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PMC11519583

Furthermore, Ror2 knockdown (KD) inhibited the adipogenic differentiation of MPs, as assessed using Oil Red O staining and differentiation marker profiling (Fig. 1c and Supplementary Fig. 2c).

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PMC11796104

By overlapping 607 host genes with 3296 mRNAs acquired in previous study, 222 common genes were obtained.

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PMC9250505

It was next examined whether the small molecule inhibitor of BADS99 phosphorylation, NPB, synergized with PARP inhibition in EOC cell lines (Fig. 2, Supplementary Fig. 2).

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PMC11122631

And, only one value (flexibility) of nine compounds was not located in the ideal zone.

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PMC9031474

Compound 35 was shown to be the most active compound.

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PMC11682172

The effects were significantly less for the cell line derived from breast cancer with affinity for brain.

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PMC11547917

The IC50 values for DPPH and ABTS were calculated by graphing concentrations of the extract against the proportional antioxidant inhibition percent .

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PMC9352806

Synchronized L1 worms were supplemented with ddH2O as control or BMS (100 μg/mL or 200 μg/mL, final concentrations) mixed with E. coli OP50 on NGM plate.

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PMC11751675

F., and demonstrated antiviral activity against HIV in C8166 cells with EC50 values of 44.0 and 41.8 μM and SI values of 5.4 and 6.2, respectively.

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PMC8998437

Notably, each form of EBV-restricted latency in the isolated cellular clones was associated with protection from apoptosis and high c-MYC expression .

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PMC11733919

The apoptotic morphotype of cell death in treated cells was assayed using Annexin V staining as a marker of apoptosis (phosphatidylserine externalization).

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PMC11394386

Cells (100,000 per well) were seeded in 24-well plates and co-transfected with PGL 4.42 and pRL-null vector (Promega, Madison, WI, USA) for normalization.

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PMC11055510

The red box is high expression in the tumor, and the gray box is the low expression in the tumor. (

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PMC9512971

A serious adverse event (prinzmetal angina) occurred in one patient in the camostat mesilate group, but it was not considered related to the study drug.

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PMC10957991

n for all samples is 3.

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PMC10362265

Nonetheless, the human tetramer stayed intact even after the disruption of one of its interfaces, reflecting the sufficiency of one intact interface for tetramer stability.

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PMC11515150

NK cells derived from PBMCs were purified via CD3 cells depletion followed by CD56 cells enrichment, and maintained in NK MACS Medium (NK basal medium (Miltenyi Biotec, Bergisch Gladbach, Germany) supplemented with 1% of NK MACS Supplement, 5% CTS Immune Cell Serum, and combination of 500 IU/mL IL-2 (SI HUAN SHENG WU, ...

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PMC7171147

Given our initial observation that FAO is upregulated in cisplatin-resistant variant of A2780 cell line (A2780cis), we sought to test whether FAO inhibition can attenuate COL11A1-induced cisplatin resistance in ovarian cancer cells.

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PMC9429973

MSI2 enhancers located in intronic regions were strongly activated in SOX11+ but not in SOX11- MCL cell lines and primary cases.

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PMC9429973

Cell viability assay and colony-forming unit assay were used to examine the response of GFI1-36S and GFI1-36N leukemic cells to palbociclib treatment.

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PMC11604830

More in detail, the PFCE‐NE accumulation was observed specifically in the right PLN, corresponding to the tumor location.

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PMC11488203

Together, these findings demonstrate growth-reducing effects of different miRs on distinct cancer cell lines suggesting potentially selective miR effects on certain tumor entities.

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PMC7757104

The MTT assay (Uniscience Corp.) was used to measure the cytotoxic effects of CDDP (Libbs Farmaceutica, Ltda.)

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PMC10788478

LGR6 overexpression confers the in vitro tumor growth and spheroid formation abilities in lung cancer cell lines. (

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PMC7039683

However, robust chromatin mark evidence from human embryonic faces and human epidermal keratinocytes suggests the lack ennhancer activity of these elements in the zebrafish and mouse embryo assays reflects a technical artifact; for instance it is possible these enhancers are not compatible with the basal promoter in th...

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PMC2777936

Expression of FZD5, FZD7, WNT5A, and POU5F1 in human germ cell tumor cell lines.

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PMC9429973

Aims: To identify the frequency, specificity and clinical significance of MIR-34B/C, MIR-34A, MIR-203 and MIR-129-2 genes methylation in Diffuse Large B-cell Lymphoma (DLBCL).

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PMC7840816

None of these patients received chemotherapy or radiotherapy before surgery, and informed consent was obtained from each patient before surgery.

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PMC11711063

Bex + Carv also reduced ZG16B levels in vivo in normal breast tissue and MDA‐MB231 tumor xenografts.

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PMC9429973

Nevertheless, infection and thrombosis are two of the main complications associated with their use, but their rates and risk factors are highly variable.

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PMC8740518

Further, down-regulation was observed for amino acids, especially isoleucine, which is consistent with up-regulation of amino acid transporter genes SLC7A5 and SLC1A3 in MM.

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PMC9429973

The proportion of pts with SVR35 was greater among those who initiated RUX earlier (≤12 mo vs >12 mo) at Wk 24 (48% vs 33%; P=0.0610) and 48 (44% vs 27%; P=0.0149; Table).

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PMC9429973

This effect was more pronounced after repeated cytarabine treatment, leading to increased proliferation of LICs and augmented leukaemia burden at relapse.

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PMC11783017

As shown in Fig. 4O, the Cis/Mn/NH@PGP treatment significantly upregulated the phosphorylation of STING, TANK binding kinase 1 (TBK1), and interferon regulatory factor 3 (IRF3) in DCs, indicating the activation of the STING pathway.

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PMC11484188

miRNA mimic and inhibitor were transfected into 293T (China Center for Type Culture Collection), U266 and RPMI-8266 cells using Lipofectamine 2000 reagent (Invitrogen; Thermo Fisher Scientific, Inc.) according to the manufacturer's protocol.

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PMC8735881

Transduced human primary CD4 T cells were infected with 1,000 TCID50 of NL4-3, and intracellular p24 and GFP expression were monitored over time by flow cytometry.

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PMC11767793

In this report, we present data on the cellular viability and corresponding particle characterization obtained with eight different cell lines that were exposed to Au-PEI and carboxylate-polyethylene-glycol-conjugated AuNPs (Au-PEG-COOH, as anionic NPs).

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PMC7369657

Healthy male BALB/c mice (6–8 weeks, 18–20 g) and male BALB/c nude mice (4–6 weeks, 16–18 g) were purchased from Beijing Vital River Laboratory Animal Technology Co. (Beijing, China).

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PMC10850553

Some signals for C5ar1 were co-localized with those for the neutrophil marker, Myeloperoxidase (Fig. 1B, Supplementary Fig. S1).

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PMC11739504

The White dotted line defines the area of the renal tubule.

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PMC11777207

Tailless constructs were made via standard cloning using primers to replace residue 276 with a stop codon so that the CD80 extracellular domain and transmembrane domain remained intact, but the C terminal tail was absent after residue 275.

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PMC8913139

miR-101 suppressed the invasion, migration, and proliferation of osteosarcoma cells by downregulating ROCK1 .

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PMC11281366

To measure ADCML, cells were treated with the Zombie NIR Fixable Viability marker (1:150 in PBS; Biolegend, #423105) and analyzed via flow cytometry.

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PMC10975211

Bioconjugation enhances specificity-controlled release and combats drug resistance, presenting a promising avenue for targeted cancer treatment.

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PMC10932641

The cells of each group in the logarithmic growth phase were digested and centrifuged in routine fashion, and then the cell precipitate was resuspended with PBS to ensure that the concentration of the cell suspension was 3×10/mL. Each 4-week-old nude mouse was inoculated with 0.2 mL of cell suspension into the subcutan...

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PMC11731161

The graphic was generated using Biorender.

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PMC9952933

At 24 h and 48 h after treatment, the malignant cells showed a treatment time-dependent reduction in cell viability.

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PMC11615101

The bar graph represents the fold change of α-Taxilin expression based on densitometric values of WB after knockdown using 25nM and 50nM Si-RNA induction and 20ng/ml TNF-α induction along with non-specific Si-RNA control. (

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PMC9587298

Secondly, we evaluated the antiglycation activity of elderberry extracts, applying cell models, Caco-2 and HepG2 cells, with characteristics and morphology of intestinal epithelium and hepatocytes, respectively, two significant barriers against toxic and xenobiotic agents in the organism.

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PMC11742431

The degradation of intracellular Survivin protein promoted the apoptosis of 5637 cells and inhibited proliferation and migration.

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PMC11725127

As depicted in Fig. 4A–D, the knockout of USP2 resulted in a reduction in the KRAS protein levels (Fig. 4A and C) but not in mRNA levels (Fig. 4B and D) in both cell lines, which was similar to the effects of GA treatment.

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PMC11514418

Pancreatic cancer has an insidious onset and a high mortality rate, and most patients were diagnosed at an advanced stage, losing the chance for surgical procedures and requiring conservative chemotherapy.

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