OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC3734024	Mice with a B cell-specific loss of FasL spontaneously develop autoantibodies despite the fact that T cells in these animals are FasL-sufficient .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Mice", "with...
PMC11541241	The viral‐mediated suppression of the plant response predisposed plants to secondary infections with Pseudomonas syringae pv.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "viral‐mediated", "suppression", "of", "the", "p...
PMC11476666	This is in line with previous structure/function studies performed on different cell types, where DHS showed a stronger effect than resveratrol, possibly due to the position of the OH in 4 and 4’f facilitating the interaction with molecules involved in cell proliferation, such as polymerases .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Comparative single-cell proteomic analysis in responders and non-responders are underway to identify proteomic correlates of favourable response vs. therapy resistance.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Comparative", "single-cell", ...
PMC11653533	It is also known by various other names, including Mistletoe Fig, Mas Cotek, Telinga Beruk, Sarawak, Kalimantan Island, and Tabat Barito.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11568601	Scale bar = 100 μm.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bar", "=", "100", "μm", "." ] } ]
PMC11659734	A statistically significant increase in the frequency of micronuclei was induced by BPP at 5 μM and above in any experimental condition.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "statist...
PMC11092382	When administered via tail vein injection to rats, sophocarpine exhibited widespread distribution in the body, with peak tissue concentrations observed within 5–20 min, and the highest levels found in the kidneys, followed by the liver, gastrointestinal tract, and lungs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5025404	Then, the mini-pools were subcloned using limiting dilution in 96-well plates as described above.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Then", ",", "the", "mini-pools", "were", "subcloned", "usin...
PMC11589157	These comprehensive genome datasets will serve as a valuable resource for future studies on the genetics and protection of gibbons and improve our understanding on the evolution of Y-chromosome-related genes in primates.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11564405	Low RILPL2 expression predicted worse overall survival (OS) in NSCLC patients (P = 0.017).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Low", "RILPL2", "expression", "predicted", ...
PMC9587298	Advanced glycation end-products (AGEs) have gained attention in the last years as the accumulation of AGEs in the body are implicated not only in normal ageing but also in the development of several chronic diseases, like diabetes mellitus and all its associated disorders such as retinopathy, neuropathy, acceleration o...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Next, we will conduct in vivo studies to verify if specific PDGFR-β inhibitors could be advantageous in the treatment of PDGFR-β T-ALL/T-LBL cases.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11615828	In the SARS‐CoV‐2 internalization experiment, cells bound with the Spike protein were monitored using live‐cell imaging over the specified duration.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "the", "SARS...
PMC11597167	However, further studies, including in vivo efficacy and safety assessments, would be needed to validate their relevant therapeutic potential.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",...
PMC7840816	Our data indicated that knockdown of SOX9 inhibited PTC cell proliferation, invasion, and epithelial–mesenchymal transition (EMT) via suppressing the Wnt/β-catenin signaling pathway.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11746942	Typically, STAT3 activation in response to IL-6 is rapid and transient.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Typically", ",", "STAT3", "activation", "in", "response", "to", "IL-6", "is", ...
PMC11634027	This established that deletion of the D motif eliminates MyoID binding, which is consistent with observations that the D motif disrupts normal hindgut looping.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973	The mean duration between the R-CHOEP cycles were 18 days, with a median of 16 days and mode of 14 days.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "mean"...
PMC11087766	P. aeruginosa cells expressing GFPmut1 (Left) or sfGFP-tagged PhiKZ gp104 (Right) infected with PhiKZ PicA H365Q mutant imaged at 30 mpi. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11787355	In c, e–h, and j, N(biological)=4.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "c", ",", "e", "–", "h", ",", "and", "j", ",", "N(biological)=4", "....
PMC9429973	EV were isolated by ultracentrifugation.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "EV", "were", "isolated", "by", "ultracentrifugation", "." ] } ]
PMC10849234	Knockdown cell-lines were generated using two rounds of 2nd generation lentiviral-mediated gene transfer.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Knockdown", "cell-lines", "were", "generated", "using", "two", "rounds", "o...
PMC2944824	The tendency to undergo apoptosis is enhanced because of higher levels of expression of genes that promote apoptosis such as the pro-apoptotic members of the Bcl2 family , .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11143482	The macroscopic view of tumour can be observed prominently at the leg part as shown in Fig. 6.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "macroscopic", "view", "of", "tu...
PMC7053076	For detection of p50, p52, p65, c-Rel or RelB, the primary antibodies recognizing an epitope on these NF-κB subunits were used.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10213199	Differentially expressed gene (DEG) distribution from the low conc.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Differentially", "expressed", "gene", "(", "DEG", ")", "distribution", "from", "the", ...
PMC11225860	Thus, total AK-A inhibition was able to limit cell cycle slippage and is synthetic lethal to CIP cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thus", ",", "total", "AK-A", ...
PMC11682525	HIF1α pathway plays a crucial role in cellular adaptation to low oxygen levels.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "HIF1α", "pathway", "plays", "a", "crucial", "role", "in", "cellular", ...
PMC11267830	Indisulam was solubilized in DMSO to create a 10 MM stock solution, which was then added to tissue culture media to achieve the desired final concentration.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11703992	First, though we comprehensively explored CD4+ Memory T cells in GCA and identified two significant genes, DDIT4 and ARHGAP15, the overall effect of two genes on GCA was unable to be evaluated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9454852	Our in vitro data strongly suggest that BOLD-100 inhibits the growth of MPM cell lines, proposing the application as a single agent, or in combination with other standard-of-care drugs, to treat MPM.Malignant mesothelioma is a rare malignancy of mesothelial cells that can manifest at any mesothelial layer, but the pleu...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11767582	The mixture was extracted 3 times with ethyl acetate.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "mixture", "was", "extracted", "3", "times", "with", "ethyl", "acetate", "." ] } ]
PMC4659567	A series of eight complexes of the general formula [Ru(η -p-cym)(naza)Cl2] (1–8; Fig 1) was prepared by a one-step synthesis using the reaction of the stoichiometric amounts of the [Ru(μ-Cl)(η -p-cym)Cl]2 dimer and appropriate naza, as described for analogical [Ru(η -p-cym)(L)Cl2] [14–22].	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11686380	Neonates were anesthetized directly on ice for 5 to 10 min until the body color becomes whitish and the body movement stops.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Neonates", "...
PMC10887351	Since their discovery in 1989, the β3-ARs’ physiology and function have been rapidly studied.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Since", "their", "discovery", "in", "1989", ",", ...
PMC6835428	Smaller delivery systems (<10 nm diameter) are mostly cleared via the blood, as they can more efficiently penetrate blood capillary walls.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11774112	C and D) Quantitative analysis of the mean fluorescence intensity of FAM.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "C", "and", "D", ")", "Quantitative", "analysis", "of", "the", "mean",...
PMC11577421	Cells were incubated with NPs (0.01–1.3 nM) for 24 h in complete medium, washed to remove excess particles, stained with PI, then analyzed by flow cytometry.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11269933	Therefore, there may be some deviations between the results and the in situ situations in oysters.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "there", "may", "be", "som...
PMC11786704	The cells were cultured at 37 °C in a CO2 incubator.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cells", "were", "cultured", "at", "37", "°", "C", "in", "a", ...
PMC7812570	Fig. 6Selective survival of human CD4+ T cells expressing GPI-m36.4 during divergent HIV-1 infections.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fig.", "6Selective", "survival", "of", "human", "CD4", "+",...
PMC11119602	Its poor prognosis is mainly due to late diagnosis, which reduces chances of survival, and to the relatively high cost and lack of availability of effective treatments, particularly in developing countries.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11488203	Fig. S7).	[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "Fig.", "S7", ")", "." ] } ]
PMC8540611	Complexes with AuNP14 had a low level of cellular uptake after 3 h incubation with the same cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Complexes", "with", "AuNP14", "had", "...
PMC6487404	Then, monolayers were pre-incubated at 37 °C for 30 min, and TEER values were measured.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Then", ",", "monolayers", "were", "pre...
PMC11774251	The results demonstrated that these targets were primarily involved in biological processes such as phosphorylation, protein kinase B signaling, and MAP kinase activity (Supplemental Figures 1B-D).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11047729	Moreover, it suppresses activation, which reduces the phosphorylation and nuclear translocation of hTERT.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "it", "suppresses", "activation", ",", "whi...
PMC8711270	Production of first-generation E1-deleted adenoviral vectors in HEK293 cells resulted in the generation of RCV with E1 sequences regained, presumably resulting from homologous recombination (Hehir et al., 1996).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11592008	Each ELISA and mRNA expression experiment was performed with three technical replicates per sample.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Each", "ELISA", "and", "mRNA", "expression", "experiment", "was", ...
PMC9966931	Most hybrids did not present dose-dependent response behavior in the SGI assays conducted in this study.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Most", "hybrids", "did", "not", "present", "dose-depen...
PMC9429973	Top treatments that the pts are currently receiving are antibiotics (48%), opioids (33%), hydroxyurea (33%), blood transfusion (31%), and iron chelation therapy (26%).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11742290	This mature form integrates its transmembrane domains into the transposon membrane before being processed and trafficked to the plasma membrane.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "mature", "form", ...
PMC11301927	In contrast, in non-Latino patients Methylobacterium spp.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "contrast", ",", "in", "non-Latino", "patients", "Methylobacterium", "spp", "." ] } ]
PMC9587298	The ion at m/z 431 was attributed to the di-MGO-cyanidin aglycone, and the ions at m/z 413, 395, 359 and 341 were attributed to the loss of one, two water molecules plus one MGO molecule, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11742231	These contributions collectively position MGATAF as a promising advancement in the field of drug response prediction, offering enhanced predictive capabilities for precision medicine initiatives.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9429973	Furthermore, NK and CD8+ T cells showed decreased PD-1 and increase of activation markers.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Furthermore", ",", "NK", "and", "CD8", "+", "T",...
PMC9429973	The initial 1-mg/kg priming dose was sufficient for this CD47 loss, which persisted with subsequent 30-mg/kg maintenance doses.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "initial", "1-mg/kg", "prim...
PMC11718817	In contrast, movement in PancOVA spheroids was directed and characterized by frequent arrests, defined as a fall of velocity below a threshold of 2 µm/min .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11422497	GISTs are now recognized as originating from interstitial cells of Cajal, leading to their classification as mesenchymal tumors emerging in the submucosa.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "GISTs",...
PMC10421378	Additionally, bacterial cells immobilized on the surface of a single microcellulose pellet were observed (Figure 4).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "bacterial", ...
PMC9352806	L1 worms (∼10000 worms each duplicate, 6 replicates per group) were treated with BMS (100 μg/mL) for 48 h. (A) OPLS-DA plots in positive ion mode, (B) OPLS-DA plots in negative ion mode, (C) Heatmaps in positive ion mode, (D) Heatmaps plots in negative ion mode, (E) Bubble plots in positive ion mode, (F) Bubble plots i...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11549062	Western blot analyses of PDGFR‐β and PTP1B. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Western", "blot", "analyses", "of", "PDGFR‐β", "and", "PTP1B", ".", "(" ] } ]
PMC11544122	However, we have yet not detected any obvious inherent features of CXCR4 that would help identify other GPCRs that might use the SNX9 mode of endocytosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11476222	Liquid chromatography–mass spectrometry (LC-MS) has gained significant attention in “omics” fields, including “gangliosidomics”.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Liquid", "ch...
PMC11740207	Briefly, VSLSLCs can directly increase their numbers and indirectly enhance the number of lower hierarchical developmental cell stages in culture.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Briefly", ",", "V...
PMC8759873	The eukaryotic expression vector pcDNA3.1(+) was from Beijing Promega Biotechnology Co., Ltd. Recombinant plasmid pcDNA3.1-VHL was constructed and identified by Tianjin Saier Biological Company.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11583690	Next, the diffusion cells were immersed in a release medium (60 mL) in stoppered Erlenmeyer flasks with continuous shaking (100 rpm) at 37 °C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9776316	We further demonstrate that cJUN-mediated XRCC4 transcription is strongly boosted by cisplatin treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "further", "demonstrate", "that", "cJUN-mediated", "XRCC4", "transcription",...
PMC11656380	Furthermore, the peptide had potent cytotoxic effects on various human leukemia and lymphoma cell lines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Furthermore", ",", "the", "peptide", "had", "potent", ...
PMC11767793	Briefly, 10 mL of aqueous bPEI25 kDa (10% mass fraction) was added to 100 mL of aqueous HAuCl4 (2.5 mmol/L) at room temperature (r.t.)	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Aims: This word was designed to illustrate the dynamic landscape of plasma proteome and metabolome in B-ALL patients during CAR-T cell therapy and detailed the kinetics of proteins and metabolites during cytokines storm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Presence of comorbidities, especially heart disease, is a risk factor for severe COVID-19 infection in our series.- Age >75 years, active malignancy at COVID-19 onset and ICU admission were mortality risk factors.- COVID-19 vaccination was a protective factor for mortality, even in this population with humoral immunity...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11683130	The inhibitory serpins can suppress the serine proteases, caspases and papain-like cysteine proteases by an irreversible suicidal mechanism (21, 25, 26) and we summarized the target enzymes inhibited by each human serpin member in Table 1 .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11463018	White solid, 76.6% yield.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "White", "solid", ",", "76.6", "%", "yield", "." ] } ]
PMC11546117	Other human cell lines have been investigated for mechanisms involving the normal physiology of the mammary gland.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Other", "human", "cell", "lines", "have", "...
PMC11746948	Half of the mixture was also treated with hydroxylamine (438227, Sigma) (pH 7.4, final concentration 500 μM) and heated for another 5 min at 95 °C to remove S-palmitoylation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11482552	This study aimed to evaluate the accuracy of sample cellularity assessment using the C-C Motif Chemokine Receptor 5 (CCR5) gene target as a marker of sample adequacy in molecular diagnostics.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9545474	Coupling constants are in Hz; abbreviations: s, singlet; d, doublet; sept, septuplet; m, multiplet.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Couplin...
PMC11013014	H NMR (400 MHz, CDCl3), δ (ppm): 7.22–7.20 (m, 2H), 6.89 (d, JHH = 8.5 Hz, 1H), 5.98 (s, 1H), 5.61 (s, 1H), 4.62 (s, 2H), 3.87–3.79 (m, 2H), 3.60 (q, JHH = 5.5 Hz, 2H), 2.50 (q, JHH = 7.4 Hz, 2H), 1.17 (t, JHH = 7.4 Hz, 3H).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10582049	Part of the samples (6 of 16) had a mixed structure with 1 predominant structural pattern.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Part", "of", "the", "samples", "(", ...
PMC11127909	Experiments were performed three times (N = 3).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Experiments", "were", "performed", "three", "times", "(", "N", "=", "3", ")", "." ] ...
PMC9429973	Currently, there are no approved criteria for selecting therapy for patients with MDS based on the classifications and prognostic scales used, treatment regimens for progression of MDS or its refractory forms.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11380329	The ratio of stained positive nuclei to unstained negative ones was counted in randomly chosen 40× magnification fields.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "ratio", "of", "stained", ...
PMC4112127	The remaining 40% of CCs are intrahepatic (ICC), arising in the bile ducts within the liver .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "remaining", "40", ...
PMC11352877	The highest cell migration was determined in endometriotic 12Z (24 h = 44.682% and 48 h = 45.237%).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "highe...
PMC8270637	Since we have determined TGF-β1 enhanced the expression of PD-1 on T cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Since", "we", "have", "determined", "TGF-β1", "enhanced", "the", "expressio...
PMC10482220	SGs contain high concentrations of RNA.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "SGs", "contain", "high", "concentrations", "of", "RNA", "." ] } ]
PMC11320834	Statistical analysis was performed using GraphPad Prism software (GraphPad Software Inc., CA, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Statistical", "analysis", "was", "performed", "us...
PMC11615218	Likewise, some other researchers have observed that increased levels of TREG in peripheral blood before and after CAR-T cell infusion were associated with nonresponse and inferior overall survival [28, 80–83].	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11699042	Cell viability data was first normalized using the measured raw viability of each control (DMSO vehicle), and the area under the curve (AUC) was computed for each cell line using the PharmacoGx package version 3.0.2 (P Smirnov, 2016) in R version 4.2.1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11474209	The focus on mitochondrial function impairment and metabolic disturbance caused by MC-LR is not notable.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "focus", "on", "mitochondrial", "function", "impairment", ...
PMC4005030	Rhus verniciflua Stokes (RVS) containing flavonoids have antioxidant effects.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Rhus", "verniciflua", "Stokes", "(", "RVS", ")", "containing", "flavonoids", "have", ...
PMC9219615	Tpz-1 (Figure 2) is a novel small-molecule thieno[2,3-c]pyrazole derivative that we recently discovered after screening 2000 compounds for novel anticancer agents within the ChemBridge DIVERset library.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5963610	Interestingly in the 3LL-model the combination with NGcGM3/VSSP vaccine virtually cured 60% of the treated mice.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Interestingly", "in", "the", "3LL-model", "the", ...
PMC5833712	No such trend in the expression of ERα has been observed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "No", "such", "trend", "in", "the", "expression", "of", "ERα", "has", "been", "o...
PMC11483468	TAT-LPTS39 suppressed the xenograft tumour growth in vivo. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "TAT-LPTS39", "suppressed", "the", "xenograft", "tumour", "growth", "in", "vivo", ".", "(" ] } ]
PMC9429973	Aims: We intend to share our practical knowledge of the encountered challenges.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ":", "We", "intend", "to", "share", "our", "practical", "knowl...
PMC9429973	No OS difference was observed but the follow-up was short (6 months).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "No", "OS", "difference", "was", "observed", "but", "the", "follo...
PMC8978939	Under pseudohypoxic conditions, we found significantly higher levels of VEGF-A and GLUT1 mRNAs on the variant cell lines compared to the one expressing WT pVHL ( Figure 2C , lower panel).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC3734024

Mice with a B cell-specific loss of FasL spontaneously develop autoantibodies despite the fact that T cells in these animals are FasL-sufficient .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Mice", "with...

PMC11541241

The viral‐mediated suppression of the plant response predisposed plants to secondary infections with Pseudomonas syringae pv.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "viral‐mediated", "suppression", "of", "the", "p...

PMC11476666

This is in line with previous structure/function studies performed on different cell types, where DHS showed a stronger effect than resveratrol, possibly due to the position of the OH in 4 and 4’f facilitating the interaction with molecules involved in cell proliferation, such as polymerases .

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PMC9429973

Comparative single-cell proteomic analysis in responders and non-responders are underway to identify proteomic correlates of favourable response vs. therapy resistance.

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PMC11653533

It is also known by various other names, including Mistletoe Fig, Mas Cotek, Telinga Beruk, Sarawak, Kalimantan Island, and Tabat Barito.

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PMC11568601

Scale bar = 100 μm.

[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "Scale", "bar", "=", "100", "μm", "." ] } ]

PMC11659734

A statistically significant increase in the frequency of micronuclei was induced by BPP at 5 μM and above in any experimental condition.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "statist...

PMC11092382

When administered via tail vein injection to rats, sophocarpine exhibited widespread distribution in the body, with peak tissue concentrations observed within 5–20 min, and the highest levels found in the kidneys, followed by the liver, gastrointestinal tract, and lungs.

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PMC5025404

Then, the mini-pools were subcloned using limiting dilution in 96-well plates as described above.

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PMC11589157

These comprehensive genome datasets will serve as a valuable resource for future studies on the genetics and protection of gibbons and improve our understanding on the evolution of Y-chromosome-related genes in primates.

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PMC11564405

Low RILPL2 expression predicted worse overall survival (OS) in NSCLC patients (P = 0.017).

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PMC9587298

Advanced glycation end-products (AGEs) have gained attention in the last years as the accumulation of AGEs in the body are implicated not only in normal ageing but also in the development of several chronic diseases, like diabetes mellitus and all its associated disorders such as retinopathy, neuropathy, acceleration o...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Next, we will conduct in vivo studies to verify if specific PDGFR-β inhibitors could be advantageous in the treatment of PDGFR-β T-ALL/T-LBL cases.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC11615828

In the SARS‐CoV‐2 internalization experiment, cells bound with the Spike protein were monitored using live‐cell imaging over the specified duration.

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PMC11597167

However, further studies, including in vivo efficacy and safety assessments, would be needed to validate their relevant therapeutic potential.

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PMC7840816

Our data indicated that knockdown of SOX9 inhibited PTC cell proliferation, invasion, and epithelial–mesenchymal transition (EMT) via suppressing the Wnt/β-catenin signaling pathway.

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PMC11746942

Typically, STAT3 activation in response to IL-6 is rapid and transient.

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PMC11634027

This established that deletion of the D motif eliminates MyoID binding, which is consistent with observations that the D motif disrupts normal hindgut looping.

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PMC9429973

The mean duration between the R-CHOEP cycles were 18 days, with a median of 16 days and mode of 14 days.

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PMC11087766

P. aeruginosa cells expressing GFPmut1 (Left) or sfGFP-tagged PhiKZ gp104 (Right) infected with PhiKZ PicA H365Q mutant imaged at 30 mpi. (

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PMC11787355

In c, e–h, and j, N(biological)=4.

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PMC9429973

EV were isolated by ultracentrifugation.

[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "EV", "were", "isolated", "by", "ultracentrifugation", "." ] } ]

PMC10849234

Knockdown cell-lines were generated using two rounds of 2nd generation lentiviral-mediated gene transfer.

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PMC2944824

The tendency to undergo apoptosis is enhanced because of higher levels of expression of genes that promote apoptosis such as the pro-apoptotic members of the Bcl2 family , .

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PMC11143482

The macroscopic view of tumour can be observed prominently at the leg part as shown in Fig. 6.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "macroscopic", "view", "of", "tu...

PMC7053076

For detection of p50, p52, p65, c-Rel or RelB, the primary antibodies recognizing an epitope on these NF-κB subunits were used.

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PMC10213199

Differentially expressed gene (DEG) distribution from the low conc.

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PMC11225860

Thus, total AK-A inhibition was able to limit cell cycle slippage and is synthetic lethal to CIP cells.

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PMC11682525

HIF1α pathway plays a crucial role in cellular adaptation to low oxygen levels.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "HIF1α", "pathway", "plays", "a", "crucial", "role", "in", "cellular", ...

PMC11267830

Indisulam was solubilized in DMSO to create a 10 MM stock solution, which was then added to tissue culture media to achieve the desired final concentration.

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PMC11703992

First, though we comprehensively explored CD4+ Memory T cells in GCA and identified two significant genes, DDIT4 and ARHGAP15, the overall effect of two genes on GCA was unable to be evaluated.

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PMC9454852

Our in vitro data strongly suggest that BOLD-100 inhibits the growth of MPM cell lines, proposing the application as a single agent, or in combination with other standard-of-care drugs, to treat MPM.Malignant mesothelioma is a rare malignancy of mesothelial cells that can manifest at any mesothelial layer, but the pleu...

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PMC11767582

The mixture was extracted 3 times with ethyl acetate.

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PMC4659567

A series of eight complexes of the general formula [Ru(η -p-cym)(naza)Cl2] (1–8; Fig 1) was prepared by a one-step synthesis using the reaction of the stoichiometric amounts of the [Ru(μ-Cl)(η -p-cym)Cl]2 dimer and appropriate naza, as described for analogical [Ru(η -p-cym)(L)Cl2] [14–22].

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PMC11686380

Neonates were anesthetized directly on ice for 5 to 10 min until the body color becomes whitish and the body movement stops.

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PMC10887351

Since their discovery in 1989, the β3-ARs’ physiology and function have been rapidly studied.

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PMC6835428

Smaller delivery systems (<10 nm diameter) are mostly cleared via the blood, as they can more efficiently penetrate blood capillary walls.

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PMC11774112

C and D) Quantitative analysis of the mean fluorescence intensity of FAM.

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PMC11577421

Cells were incubated with NPs (0.01–1.3 nM) for 24 h in complete medium, washed to remove excess particles, stained with PI, then analyzed by flow cytometry.

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PMC11269933

Therefore, there may be some deviations between the results and the in situ situations in oysters.

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PMC11786704

The cells were cultured at 37 °C in a CO2 incubator.

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PMC7812570

Fig. 6Selective survival of human CD4+ T cells expressing GPI-m36.4 during divergent HIV-1 infections.

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PMC11119602

Its poor prognosis is mainly due to late diagnosis, which reduces chances of survival, and to the relatively high cost and lack of availability of effective treatments, particularly in developing countries.

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PMC11488203

Fig. S7).

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PMC8540611

Complexes with AuNP14 had a low level of cellular uptake after 3 h incubation with the same cells.

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PMC6487404

Then, monolayers were pre-incubated at 37 °C for 30 min, and TEER values were measured.

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PMC11774251

The results demonstrated that these targets were primarily involved in biological processes such as phosphorylation, protein kinase B signaling, and MAP kinase activity (Supplemental Figures 1B-D).

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PMC11047729

Moreover, it suppresses activation, which reduces the phosphorylation and nuclear translocation of hTERT.

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PMC8711270

Production of first-generation E1-deleted adenoviral vectors in HEK293 cells resulted in the generation of RCV with E1 sequences regained, presumably resulting from homologous recombination (Hehir et al., 1996).

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PMC11592008

Each ELISA and mRNA expression experiment was performed with three technical replicates per sample.

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PMC9966931

Most hybrids did not present dose-dependent response behavior in the SGI assays conducted in this study.

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PMC9429973

Top treatments that the pts are currently receiving are antibiotics (48%), opioids (33%), hydroxyurea (33%), blood transfusion (31%), and iron chelation therapy (26%).

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PMC11742290

This mature form integrates its transmembrane domains into the transposon membrane before being processed and trafficked to the plasma membrane.

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PMC11301927

In contrast, in non-Latino patients Methylobacterium spp.

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PMC9587298

The ion at m/z 431 was attributed to the di-MGO-cyanidin aglycone, and the ions at m/z 413, 395, 359 and 341 were attributed to the loss of one, two water molecules plus one MGO molecule, respectively.

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PMC11742231

These contributions collectively position MGATAF as a promising advancement in the field of drug response prediction, offering enhanced predictive capabilities for precision medicine initiatives.

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PMC9429973

Furthermore, NK and CD8+ T cells showed decreased PD-1 and increase of activation markers.

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PMC9429973

The initial 1-mg/kg priming dose was sufficient for this CD47 loss, which persisted with subsequent 30-mg/kg maintenance doses.

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PMC11718817

In contrast, movement in PancOVA spheroids was directed and characterized by frequent arrests, defined as a fall of velocity below a threshold of 2 µm/min .

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PMC11422497

GISTs are now recognized as originating from interstitial cells of Cajal, leading to their classification as mesenchymal tumors emerging in the submucosa.

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PMC10421378

Additionally, bacterial cells immobilized on the surface of a single microcellulose pellet were observed (Figure 4).

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PMC9352806

L1 worms (∼10000 worms each duplicate, 6 replicates per group) were treated with BMS (100 μg/mL) for 48 h. (A) OPLS-DA plots in positive ion mode, (B) OPLS-DA plots in negative ion mode, (C) Heatmaps in positive ion mode, (D) Heatmaps plots in negative ion mode, (E) Bubble plots in positive ion mode, (F) Bubble plots i...

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PMC11549062

Western blot analyses of PDGFR‐β and PTP1B. (

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PMC11544122

However, we have yet not detected any obvious inherent features of CXCR4 that would help identify other GPCRs that might use the SNX9 mode of endocytosis.

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PMC11476222

Liquid chromatography–mass spectrometry (LC-MS) has gained significant attention in “omics” fields, including “gangliosidomics”.

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PMC11740207

Briefly, VSLSLCs can directly increase their numbers and indirectly enhance the number of lower hierarchical developmental cell stages in culture.

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PMC8759873

The eukaryotic expression vector pcDNA3.1(+) was from Beijing Promega Biotechnology Co., Ltd. Recombinant plasmid pcDNA3.1-VHL was constructed and identified by Tianjin Saier Biological Company.

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PMC11583690

Next, the diffusion cells were immersed in a release medium (60 mL) in stoppered Erlenmeyer flasks with continuous shaking (100 rpm) at 37 °C.

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PMC9776316

We further demonstrate that cJUN-mediated XRCC4 transcription is strongly boosted by cisplatin treatment.

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PMC11656380

Furthermore, the peptide had potent cytotoxic effects on various human leukemia and lymphoma cell lines.

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PMC11767793

Briefly, 10 mL of aqueous bPEI25 kDa (10% mass fraction) was added to 100 mL of aqueous HAuCl4 (2.5 mmol/L) at room temperature (r.t.)

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PMC9429973

Aims: This word was designed to illustrate the dynamic landscape of plasma proteome and metabolome in B-ALL patients during CAR-T cell therapy and detailed the kinetics of proteins and metabolites during cytokines storm.

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PMC9429973

Presence of comorbidities, especially heart disease, is a risk factor for severe COVID-19 infection in our series.- Age >75 years, active malignancy at COVID-19 onset and ICU admission were mortality risk factors.- COVID-19 vaccination was a protective factor for mortality, even in this population with humoral immunity...

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PMC11683130

The inhibitory serpins can suppress the serine proteases, caspases and papain-like cysteine proteases by an irreversible suicidal mechanism (21, 25, 26) and we summarized the target enzymes inhibited by each human serpin member in Table 1 .

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PMC11463018

White solid, 76.6% yield.

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PMC11546117

Other human cell lines have been investigated for mechanisms involving the normal physiology of the mammary gland.

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PMC11746948

Half of the mixture was also treated with hydroxylamine (438227, Sigma) (pH 7.4, final concentration 500 μM) and heated for another 5 min at 95 °C to remove S-palmitoylation.

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PMC11482552

This study aimed to evaluate the accuracy of sample cellularity assessment using the C-C Motif Chemokine Receptor 5 (CCR5) gene target as a marker of sample adequacy in molecular diagnostics.

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PMC9545474

Coupling constants are in Hz; abbreviations: s, singlet; d, doublet; sept, septuplet; m, multiplet.

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PMC11013014

H NMR (400 MHz, CDCl3), δ (ppm): 7.22–7.20 (m, 2H), 6.89 (d, JHH = 8.5 Hz, 1H), 5.98 (s, 1H), 5.61 (s, 1H), 4.62 (s, 2H), 3.87–3.79 (m, 2H), 3.60 (q, JHH = 5.5 Hz, 2H), 2.50 (q, JHH = 7.4 Hz, 2H), 1.17 (t, JHH = 7.4 Hz, 3H).

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PMC10582049

Part of the samples (6 of 16) had a mixed structure with 1 predominant structural pattern.

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PMC11127909

Experiments were performed three times (N = 3).

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PMC9429973

Currently, there are no approved criteria for selecting therapy for patients with MDS based on the classifications and prognostic scales used, treatment regimens for progression of MDS or its refractory forms.

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PMC11380329

The ratio of stained positive nuclei to unstained negative ones was counted in randomly chosen 40× magnification fields.

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PMC4112127

The remaining 40% of CCs are intrahepatic (ICC), arising in the bile ducts within the liver .

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PMC11352877

The highest cell migration was determined in endometriotic 12Z (24 h = 44.682% and 48 h = 45.237%).

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PMC8270637

Since we have determined TGF-β1 enhanced the expression of PD-1 on T cells.

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PMC10482220

SGs contain high concentrations of RNA.

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PMC11320834

Statistical analysis was performed using GraphPad Prism software (GraphPad Software Inc., CA, USA).

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PMC11615218

Likewise, some other researchers have observed that increased levels of TREG in peripheral blood before and after CAR-T cell infusion were associated with nonresponse and inferior overall survival [28, 80–83].

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PMC11699042

Cell viability data was first normalized using the measured raw viability of each control (DMSO vehicle), and the area under the curve (AUC) was computed for each cell line using the PharmacoGx package version 3.0.2 (P Smirnov, 2016) in R version 4.2.1.

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PMC11474209

The focus on mitochondrial function impairment and metabolic disturbance caused by MC-LR is not notable.

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PMC4005030

Rhus verniciflua Stokes (RVS) containing flavonoids have antioxidant effects.

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PMC9219615

Tpz-1 (Figure 2) is a novel small-molecule thieno[2,3-c]pyrazole derivative that we recently discovered after screening 2000 compounds for novel anticancer agents within the ChemBridge DIVERset library.

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PMC5963610

Interestingly in the 3LL-model the combination with NGcGM3/VSSP vaccine virtually cured 60% of the treated mice.

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PMC5833712

No such trend in the expression of ERα has been observed.

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PMC11483468

TAT-LPTS39 suppressed the xenograft tumour growth in vivo. (

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PMC9429973

Aims: We intend to share our practical knowledge of the encountered challenges.

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PMC9429973

No OS difference was observed but the follow-up was short (6 months).

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PMC8978939

Under pseudohypoxic conditions, we found significantly higher levels of VEGF-A and GLUT1 mRNAs on the variant cell lines compared to the one expressing WT pVHL ( Figure 2C , lower panel).

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