Datasets:
OTAR3088
/
BioData-CellLine_annotated

Dataset card Data Studio Files
xet
 Community
1
PMCID
string
Sentences
string
ner
list
PMC11675244
The development of multi-task nanoparticles was proposed, for a more specific target with improved drug dosing and also the possibility of using drug combination cargo for a more versatile application that would focus on at least one mechanism involved in cancers, unlike free drugs currently used in common therapies.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11767817
A previous study by Laali et al. showed that fluorinated curcumin–BF2 adducts fitted in the tunnel-like binding pocket of HER2, where they mainly established hydrophobic contacts .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11754784
To characterize the binding ability of Nb-S and aptamers (Sgc8c and Sgc4f) to different cell lines, 1 × 10 RPMI-CEM, Ramos, K562, RPMI-8226 and Jurkat were incubated at 37 °C for 1 h with 100 nM FAM-labeled Nb-S, TAMRA-labeled Sgc8c, and Cy5-labeled Sgc4f, respectively.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-...
PMC10759659
Two-sided Fisher’s exact tests and Mann‒Whitney U tests were applied to compare the two groups.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Two-sided", "Fisher", "’s", "exact", "tests", "and", ...
PMC11413393
c Western blot analysis of asymmetric dimethylarginine (aDMA) changes in 786-0 and RCC243 cells after MS023 treatment using the ASYM25 antibody for indicated period of time.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", ...
PMC11502443
Therefore, additional characterization is required to determine whether GIP receptor couples to G proteins beyond Gαs.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "additional", "characterization", ...
PMC11555465
Cells were cultured in a humidified incubator at 37°C with 5% CO2.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", "were", "cultured", "in", "a", "humidified", "incub...
PMC10154881
Cell fixation and permeabilization were performed using IC fixation buffer and permeabilization buffer (eBioscience) according to the manufacturer's instructions, followed by intracellular staining.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8711270
Products from the E3 gene region are not essential for viral replication and hence, does not need to be complemented.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Products", "from", ...
PMC11757131
This study provides an important methodological reference for improving the composition of sow milk by nutritional means.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "study", "provides", "an", "important", ...
PMC9429973
They may also represent suitable targets for measurable residual disease (MRD) detection, but have not yet been evaluated for this purpose separately.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11682172
Fig. 3Coronin-1 A is upregulated in breast cancer cells after contact with T lymphocytes. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fig.", "3Coronin-1", "A", "is", "upregulated", "in", "breas...
PMC8010066
The most notable repressive effect of S.aureus was observed for the PA-2 strain.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "most", "notable", "repressive", "effect", "of", "S.aureus", "was", ...
PMC10243817
The immunoprecipitates were incubated with protein A or G Dynabeads and the enriched MEX3B binding RNAs were extracted by using TRIzol (InvitroGen).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11283030
Briefly, total RNA was isolated using the RNAeasy kit (Beyotime, China), and transcribed to cDNA using PrimeScript RT Kit (37 °C 15 min, 85 °C 5 s, and held at 4 °C until use; Takara, China).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Consequently, the association of SI plus GC displayed a synergistic effect in multiple preclinical models, including steroid-resistant cell lines, primary leukemia cells, and PDX models.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC2777936
The induction of these species may be due to changes in chromatin resulting from the loss of POU5F1 activity or other mechanisms.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "induc...
PMC11754784
a Schematic figure of DNP1-based cellular recognition.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "a", "Schematic", "figure", "of", "DNP1-based", "cellular", "recognition", "." ] } ]
PMC11047729
The effect of caspase inhibitors was also examined during the study.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "effect", "of", "caspase", "inhibitors", "was", "also", "examined", "during", "...
PMC11306019
Phase-contrast microscopic images of cell density on the 1st, 4th, 8th, 11th, and 14th day.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Phase-contrast", "microscopic", "images...
PMC9429973
Image: Summary/Conclusion: ctDNA status post treatment was relevant to clinical response and was of prognostic significance for disease progress and relapse.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Image",...
PMC11471157
Image showing spheroids of HaCaT cells and NIH/3T3 cells stained for the intermediate filament marker vimentin.
[ { "tags": [ "O", "O", "O", "O", "B-CellLine", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Image", "showing", "spheroids", "of", "HaC...
PMC11024707
It was left for 2 minutes and then centrifuged at 12,000 g for 30 seconds.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "It", "was", "left", "for", "2", "minutes", "and", "th...
PMC11322866
We have previously demonstrated that GSK126, a specific EZH2 inhibitor, exhibits anti-MM therapeutic efficacy and safety in vivo and in vitro; however, its specific mechanism remains unclear.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11672881
Genes like CYP4F11 and GPX3 are involved in the oxidative stress response, supporting the GO analysis results that showed significant enrichment of the oxidative stress and redox processes for the combination treatment .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10723784
Notably, when cells were treated for 96 h, the IC50s were 2.57 ± 0.3 μM and 44.9 ± 3.5 μM in A2780 and A2780/CP70 cells, respectively.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLin...
PMC11544122
No. CRL-1573), and HeLa cells (cat.
[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "B-CellLine", "O", "O", "O", "O" ], "tokens": [ "No.", "CRL-1573", ")", ",", "and", "HeLa", "cells", "(", "cat", "." ] } ]
PMC11694066
Unscaled AUC values for each drug were also standardized, generating robust Z-scores based on the median AUC effect in a panel of 92 cancer cell lines (Supplementary Tables S2–S4) and the median absolute deviation of these effects.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10212663
The transwell assay was used, and results revealed that sh‐RANKL significantly the invasive capabilities of A427 cells (Figure 5(c),(d)).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC10854447
The substitution on the phenyl group of the 1,2,4-oxadiazole moiety significantly increased the activity (except for methyl group) of 7a–o, and substitution with methoxy groups increased the activity more than halogen atoms.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11791203
No.Plant extractIC50Value (µg/ml)HT29HaCaTp value1Chloroform extract31.97 ± 3.07> 100> 0.0012Petroleum ether extract76.58 ± 4.74> 100> 0.001The values are expressed as mean ± SEM (n = 6).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11638288
Identifying the ligands of NKp46 and elucidating the precise binding sites could play a pivotal role in anti-infective therapy.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Identifying", "the", "ligands", "...
PMC11593031
Methods: The Neuro-2a cell line and two of its derivatives, Neuro-2a TR-alpha and Neuro-2a TR-beta, were analyzed for their chromosomal constitution using molecular cytogenetic approaches.
[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O"...
PMC6934009
The membranes were incubated overnight at 4 ˚C with primary antibodies: anti-LC3, anti-RIP3, anti-caspase 3, anti-LC3I, anti-LC3II, anti-caspase 8, ant-caspase 9, and anti-Poly (ADP-ribose) polymerase (PARP).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9243326
Large-scale PCR was performed for subsequent SMRTbell library construction.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Large-scale", "PCR", "was", "performed", "for", "subsequent", "SMRTbell", "library", "construction", "." ...
PMC11675244
Proliferation is also stimulated by activation of the highly conserved cyclin Y, with indispensable role in mitosis regulation (G2/M transition) .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Prolife...
PMC11525293
A HaCaT and A431 cells were transiently transfected with 100 and 250 ng of CRBN encoding plasmid.
[ { "tags": [ "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "HaCaT", "and", "A431", "ce...
PMC11745823
In addition, TUNEL assay results showed that overexpression of RIT1 inhibited cell apoptosis, while knockdown of c‐Myc weakened the above effect (Figure S3B).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6835762
It has often been suggested that PGA will undergo enzymatic degradation as a result of the presence of an ester bond in the polymer backbone and the enzymatic synthesis used to produce the polymer which uses the reverse reaction of a degradative enzyme.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9268620
Damnacanthal, on the other hand, only showed high percentages of apoptotic cell for the two highest concentrations (30 and 10 μg/mL).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10907726
Western blot was employed to measure the relative expressions of EGFR, p-ERK/ERK, PI3K, p-AKT/AKT, mTOR and p-mTOR in OS cells. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11228511
P < 0.001. (
[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "P", "<", "0.001", ".", "(" ] } ]
PMC11471176
For carnosine these were approximately 55, 110, 221, and 442 mM. For the standard kit inhibitor concentrations were 6.25, 12.5, 25 and 50 nM. These concentrations are per the protocol of the kit.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9684669
To quantify these enhanced anticancer effects, we computed the combinational index (CI) (CI<1, synergism; CI=1, additive; CI>1, antagonism) (35).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5854676
Mathematical model is shown in Eq. (3).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Mathematical", "model", "is", "shown", "in", "Eq.", "(", "3", ")", "." ] } ]
PMC9429973
PK and PD parameters will be characterized for LANRA monotherapy and when co-administered with gilteritinib.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "PK", "and", "PD", "parameters", "will", "be", "characterize...
PMC11204465
In the next step, DMST is converted to STC by the action of O-methyltransferase B encoded by the aflO (omtB) gene.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC6442998
GIST48 cells showed a high expression of αSMA mRNA and protein compared to GIST882 cells (Figure 2C and 2D).
[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "GIST48", ...
PMC11529598
p < 0.05.
[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "p", "<", "0.05", "." ] } ]
PMC11574271
Fig. 4RON modulates the expression of MMP12 via inhibiting ubiquitination of the transcription factor HIF-2α.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fig.", "4RON", "modulates", "the", "expression", "of", "MMP...
PMC2193049
Cells were transfected using the same protocol as for the metabolic labeling with the following modifications: 10 cells were transfected in 96-well, round bottom microtiter plates with 200 ng plasmid DNA and 1 μl Lipofectamine in a final volume of 100 μl DMEM.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Adolescent and yound adults (AYA) were treated with pediatric inspired protocols or GMALL like protocols.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Adolescent", "and", "yound", "adults", "(", ...
PMC11469524
Stars denote coefficients that are significantly different (i.e., 95%-point wise confidence intervals do not overlap, see S1 Table). (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Stars",...
PMC11792090
Cytotoxicity of NK cells against various CAR-T cells, determined by comparing cell numbers before and after co-culture. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cytotoxicity", "of", "NK", "cells...
PMC11388384
We found that single trajectories of SHH-Halo transitioned between multiple diffusive populations (Fig. 5 B and C).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "found", "that", "single", ...
PMC11629143
Use of dCas9‐TET1 and sgRNAs targeting the CMV promoter fully reversed the high CpG methylation observed after 10 weeks in culture to levels seen when culture began (Figure 3A).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8864075
Furthermore, chemoproteomics was used to elucidate the changes of downstream protein networks after TFEA inhibited the PI3K-AKT-TWIST1 axis, and it was found that the glycolysis pathway may play an important role.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10092581
Error bars indicate S.D. (B) effect of gold(I) and silver(I) compounds on hydrogen peroxide formation in H157 cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "Error", ...
PMC11297139
e Odds ratio that an activated gene is included in the cancer-related GO terms shown in Fig. 4c, comparing the genes linked to the upregulated cREs versus unlinked genes (P values for the enrichment of the linked genes versus the unlinked genes: migration = 0.034, cell adhesion = 0.038, two-sided Fisher’s exact test).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10899471
Based on the predicted binding sites of miR-939-3p in the 3’ UTR of BATF2 mRNA ( Figure 4B ), we postulated that miR-939-3p could suppress BATF2 expression through binding to its 3’ UTR.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11726848
In the case of HDR irradiation, the percentage of DNA damage was 5 and 8% for irradiation at doses of 4 and 8 Gy, respectively.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11783017
Multiple pieces of evidence indicate that the oncogene MYC can promote the occurrence, progression, and metastasis of various malignant tumors, including glioblastoma, triple-negative breast cancer, and OS.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10958426
All patients’ ploidy CNV regions are shown on a circos plot .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "patients", "’", "ploidy", "CNV", "regions", "are", "shown", "on", "...
PMC11799620
Meanwhile, the Cd-exposure significantly decreased (0.01) viability when compared to control cells (Fig. 8b, 9b).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Meanwhile", ",", ...
PMC11389534
Furthermore, with the progress of fundamental biological research, increasing attention has been paid towards the UFM1 system for its potential value in clinical diagnosis and treatment.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8750422
Moreover, we show that the expression of EMT markers was regulated according to the expression of GPR87.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "we", "show", "that", ...
PMC11552389
The forkhead box (FOX) transcription factor family member FOXN3 is a key regulator of cellular proliferation, migration, and invasivity.17,18 FOXN3 has recently been recognized as a key mediator of many cancers, including melanoma,18 papillary thyroid,19 adult acute myeloid leukemia,20 and breast cancer.21 However, the...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11665555
Therefore, to simulate the metabolic effect of targeting OXCT1, we exploited the chiral property of βHB by treating the cells with the metabolically inactive enantiomer S-βHB (5 mM) at a dose range of natural ketosis without causing severe ketoacidosis (30, 31).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11541409
Serrano, C., et al., 1489MO A phase Ib/II study of selinexor as single agent and in combination with imatinib in patients with advanced gastrointestinal stromal tumor (GIST): SeliGIST/GEIS-41 trial.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11082662
To assess the differences in the OS between the two groups, Kaplan-Meier analysis was conducted.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "assess", "the", "differences", "in", "the", ...
PMC9727330
The student's two tails t-test was used to determine the significance of differentiated Ct values. (*)
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "student", "'s", "two", ...
PMC7171147
FAO upregulation increases both mitochondrial function and cellular pools of NADH and ATP (Fig. 1e, S6D).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "FAO", "upregulation", "increases", ...
PMC10565698
Clinicopathological data showed that circUSP10 was associated with tumor size and TNM stage and that higher circUSP10 levels corresponded to shorter OS in patients with LC.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11348300
The use of PpIX as a marker though has not extended beyond these particular organ sites because of more substantial normal tissue uptake and therefore lower contrast.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10419319
These results suggest that isoalantolactone, either alone or in combination with cisplatin, can effectively overcome cisplatin resistance in OC.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "results", ...
PMC11457557
Most miRNAs are intracellular, and their dysregulation has been discovered as an early biomarker in many disorders.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Most", "miRNAs", "are", "intracellular", ...
PMC9429973
BPGM enzyme activity was determined as described by Beutler.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "BPGM", "enzyme", "activity", "was", "determined", "as", "described", "by", "Beutler", "." ] } ]
PMC9118379
Thus, the variant peptide identification of these spectra was insufficiently confirmed.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thus", ",", "the", "variant", "peptide", "identification", "of", "these", "spect...
PMC11774251
Representative KEGG pathways enriched in downregulated genes in mouse skin. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Representative", "KEGG", "pathways", "enriched", "in", "downregulated", "genes", "in", "mou...
PMC11774251
Functional annotation and pathway analysis were performed through the DAVID platform (https://david.ncifcrf.gov/).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Functional", "annotation", "and", "pathway", "analysis", "were", "perf...
PMC7823217
However, ionic, or chemical crosslinking agents used for hydrogel systems can also affect cell viability and phenotype of the tumour construct.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However...
PMC10595704
The A549 cells were treated with concentrations of PS-NP (800 nm diameter) in the range of 10-500 mg/ml and for different time intervals up to 96 h. Cell viability, oxidative stress and senescence, were evaluated by commercially available kits, apoptosis was assessed by cytofluorimetric assay.
[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11680982
The primary antibodies employed included rabbit primary antibody ER (1:500; 21244-1-AP, Proteintech, China), and rabbit primary antibody PR (1:200; 25871-1-AP, Proteintech, China), rabbit primary antibody HER2 (1:300; 18299-1-AP, Proteintech, China).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11127909
Simultaneously, in Tube B, we mixed 4 μg of PSPAX2, 2 μg of PMD2G, 6 μg of the target plasmid, and 48 μl of P3000 with 2 ml of Opti medium.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11541241
We find that TSC1‐TSC2 only exists in B. graminis f. sp. tritici, M. oryzae, and U. maydis; however, Rheb homologues are identified in all fungal species in the present study, suggesting the altered TSC1/TSC2‐Rheb pathway in these species.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10969097
Data were extracted that provided information on treatment efficacy and the molecular mechanisms underlying the synergy between mushroom extracts and anticancer therapies.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "were...
PMC10565698
9Mechanistic sketch of the role of circUSP10 in LC.Fig.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "9Mechanistic", "sketch", "of", "the", "role", "of", "circUSP10", "in", "LC.Fig", "." ] } ]
PMC11538390
Percent input identified by ChIP-qPCR for (b) anti-H3K27Ac and (c) anti-IRF6, respectively, in iOECs heterozygous for rs570516915 using primers specific to the MCS-9.7 enhancer site or, as a negative control, to a region 103.7 kb upstream IRF6 transcription start site that did not harbor active elements identified from...
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11765988
The median age of sarcoidosis onset in patients who develop lymphoma is over 40 years, approximately 10 years older than in those with sarcoidosis unaccompanied by cancer.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11786767
∗∗∗P < 0.001; unpaired two-tailed t-test.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "∗∗∗P", "<", "0.001", ";", "unpaired", "two-tailed", "t-test", "." ] } ]
PMC11591794
The findings showed that 530 genes were involved in the enrichment process and 331 pathways were human papillomavirus infection and cervical cancer-related, exhibiting a significant correlation with target genes (p < 0.05) (Figure 7 and Figure 8).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11686380
In this study, we identified a heterozygous missense variation in the GAP43 gene [NM_001130064.2: c.436G > A/p.(E146K)] in a patient with ID, short stature, and neurodevelopmental disorders.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8143558
The roots of E. camaldulensis Dehnh yielded 341 mg/g when they were extracted with water, and 261 mg/g with ethanol.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "roots", "o...
PMC10344560
His onychomycosis was another site of fungal infections, but we could not conclude it was the risk factor because the fungal culture of toenail scrapings of our patient demonstrated Penicillium sp., different from his effluent.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8584666
Staining of cells to detect phosphorylated p65-NF-κB was performed as described previously .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Staining", "of", "cells", "to", "detect", "phosphorylated", "p65-NF-κB", "was", ...
PMC10545062
At the end of study (T330), UOP was 9.24 mL/kg (IQR, 6.04–10.71) for SCC and 7.12 mL/kg (IQR, 5.12–8.24) for SCC+, p = 0.18.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11763111
Research has shown that TCR knockdown in universal CAR-T cells can effectively mitigate GvHD in recipients .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Research", "has", "shown", "that", "TCR", "knockdown",...
PMC11680578
p < 0.001 as compared to that of the RGZ group.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "p", "<", "0.001", "as", "compared", "to", "that", "of", "the", "RGZ", "group", ...
PMC9812014
According to a Western blot analysis of HIV envelope proteins generated in transfected 293T cells and isolated virions, fangchinoline lowered HIV-1 gp160 processing, resulting in less envelope glycoprotein integration into nascent virions .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC10170482
Previously, it was found that confocal fluorescent imaging assessment of mitochondrial ROS is in good agreement with electron spin resonance spectroscopy.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Previously", ...