OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC9960565	BJ cells were cultured in D-MEM medium.	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "BJ", "cells", "were", "cultured", "in", "D-MEM", "medium", "." ] } ]
PMC3681794	The introduction of dose intensive combination chemotherapy has increased the overall survival for osteosarcoma patients to over 70%. ,	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "introduction", "of", ...
PMC11740207	During gastrulation, EpibCs migrate into the embryo, giving rise to ectodermal progenitor cells (EcPCs), mesoderm progenitor cells (MdPCs), endodermal progenitor cells (EnPCs), and PGCs (Tam and Behringer, 1997).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11471176	A mixture of DMSO and media was used to dissolve the higher concentrations.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "mixture", "of", "DMSO", "and", "media", "was", "used", "to", ...
PMC11736898	Tissue samples from adults were collected as de-identified samples; this collection was designated as ‘not human subjects research’ by the UC IRB and therefore did not require informed consent.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11806613	10 luciferase (Luc)-expressing MDA-MB-231 cells were injected into the mammary fat pad of NSG mice (each group, n = 10).	[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11727000	Secondary antibodies conjugated to HRP were purchased from Cell Signaling Technology.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Secondary", "antibodies", "conjugated", "to", "HRP", "were", "purchased", "from", "Cell", ...
PMC6835428	Additionally, tumor accumulation is modest for both methods, most likely due to passive targeting.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "tumor", "accumulation", "is", "mo...
PMC9429973	Image: Summary/Conclusion: In our series, 13.5 % of patients had a potential HMMS, being the incidence higher in those with a therapy-related neoplasm (30.7%).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The limitation of the study is in the small numbers of the analysed population and the absent of the control comparative group.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "limit...
PMC9429973	Methods: We used mito-QC reporter mice and mitochondrial stain to analyze mitochondrial network upon in vitro treatment of metabolic modulator.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Methods", ":", "W...
PMC11021472	The fraction of the total RNA present in the cytoplasm (light grey, CF) and nucleus (dark grey, NF) is indicated.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11360263	Studies have demonstrated that the acquisition of EMT and stemness properties enhances the invasiveness and metastatic potential of cancer cells within tumors .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Studies", "h...
PMC9429973	EASIX [lactate dehydrogenase (U/L) x creatinine (mg/dl) / platelets (10/L)] and mEASIX [lactate dehydrogenase (U/L) x C reactive protein (CRP) (mg/dl) / platelets (10/L)] scores were calculated on days -7, 0, +3 and +7.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8348645	Table 1 given bellow mentions the sequence of the primers used.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Table", "1", "given", "bellow", "mentions", "the", "sequence", "of", "the", "primers"...
PMC11768281	T cells are critical players in the immune response to Plasmodium infection, with different subtypes contributing distinct roles at various stages of the disease.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10891340	The mouse BCL2 like 13 is involved in CCCP-induced mitochondrial fragmentation and mitophagy through LIR-mediated LC3B binding (Murakawa et al., 2015).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11173119	The qPCR reactions for each sample were run in triplicate.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "qPCR", "reactions", "for", "each", "sample", "were", "run", "in", "triplicate", "."...
PMC10335954	In the stomach, chronic inflammation from Helicobacter pylori infection accounts for about 90% of non-cardia GC cases (Plummer et al. 2015).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC7081114	Univariate and multivariate analyses of disease-free survival in 186 patients with hepatocellular carcinoma P < 0.05 was considered significant, P < 0.05, P < 0.01.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11612794	Immunoprecipitation using anti-FLAG antibody in AID-based CENP-T conditional knockdown CENP-C/GFP-Dsn1 cells expressing 3xFLAG-CENP-T, 3xFLAG-CENP-T, or 3xFLAG-CENP-T. Cells were cultured with IAA for 12 h and nocodazole was added for last 10 h before immunoprecipitation experiments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9872547	Curcumin can arrest the proliferation of cervical cancer cells depending on the time and concentration, and it is more active in HPV-infected cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11534035	Migration in A431 vulvar SCC cells is reduced in SERPINE1/PAI1 knockdown cells.	[ { "tags": [ "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Migration", "in", "A431", "vulvar", "SCC", "cells", "is", "reduced", "i...
PMC10529414	ChIP peaks (−q value 0.05) were called against the input-control sample from the filtered BAM files using the MACS2 peak caller.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ChIP", ...
PMC9429973	5y OS was 64.3% (95% CI 44.9-83.7%), median OS 8.7years (95% CI 2.634 – 14.894).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11633763	ECAR of USP22‐overexpression U2OS cells transfected with shβ‐catenin. (	[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ECAR", "of", "USP22‐overexpression", "U2OS", "cells", "transfected", "with", "shβ‐catenin", ".", "...
PMC10955424	Malignant ascites untreated (n = 8), cirrhosis ascites (n = 3) and chemoresistance-inducing cirrhosis ascites (n = 1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11194678	After 24–36 h, cells were fixed by 4% paraformaldehyde.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "24–36", "h", ",", "cells", "were", "fixed", "by", "4", "%", "paraforma...
PMC9325715	Iron stock solution with a concentration of ≈ 6 g/L was prepared from ammonium iron (III) citrate by dissolution in deionized water.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC10577955	Non-small-cell lung carcinoma (NSCLC) is a type of epithelial lung cancer accounting for about 85% of all lung cancers.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Non-small-cell", ...
PMC11739504	Unexpectedly, the western blotting results indicated that the majority of IFT components decreased after 24 h of serum starvation, which is at the maturation stage of ciliogenesis, whereas the mRNA levels either increased slightly or remained unchanged (Fig. 3c and Supplementary Fig. 1b and d).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6461034	For lysis, use the same “lysis buffer” (already containing lysate from the first three dishes) from the labeled tube prepared in the previous step.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8494202	GSEA was used to analyze the potential cellular signaling pathways associated with CKAP2L.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "GSEA", "was", "used", "to", "analyze", "the", "potential", "cellular", ...
PMC11694346	This distribution further supports that the PET process from BT-NH to Cl-DNBS effectively quenches the dye's fluorescence.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "distribution", "further", "supports"...
PMC11754436	lncRNAs can regulate the biological processes of numerous diseases, including cancer.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "lncRNAs", "can", "regulate", "the", "biological", "processes", "of", "numerous", ...
PMC11733919	The iron phase (VFe–O) was retained after water transference.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "iron", "phase", "(", "VFe", "–", "O", ")", "was", "retai...
PMC11541409	Annals of Oncology, 2024; 10.1016/j.annonc.2024.08.2343.This reference is of outstanding importance because it clearly suggests that 6 years of imatinib treatment is better than 3 years of imatinib treatment in reducing recurrence of GIST.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11244823	The vaccinated horses were vastly over-represented in the gD1_83-positive group.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "vaccinated", "horses", "were", "vastly", "over-represented", "in", "the", "gD1_83-positive", ...
PMC10936243	They were asked specifically about the relationship between bedding and post-operative pain in cats, and a variety of different answers emerged.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "They", "were...
PMC8701144	All of the reported protein identifications were statistically significant (p < 0.05) in Mascot and filtered in Proteome Discoverer Software (Thermo Fisher Scientific) for at least medium confidence identifications.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The primary endpoint is safety (incidence of dose limiting toxicities [DLTs]).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "primary", "endpoint", "is", "safety", "(", "incidenc...
PMC8316344	Iron absorption, transfer, storage, and retrieval are tightly regulated by numerous mechanisms .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Iron", "absorption", ",", "transfer", ",", "storage", ",", ...
PMC9261184	This study provides the first measurement and modeling of total methane and CO2 emissions from an LNG carrier on a round trip voyage from the USA to Belgium and back, including loading, laden voyage, unloading, and ballast voyage, measuring emissions from exhaust stacks, vents, and fugitives.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7504302	Mechanistically, ALCAM enhanced the malignant features of mesothelioma cells and positively contributed to MPM progression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Mechanistically", ",", "ALCAM", "enhanced", "the", "ma...
PMC11470381	Use the freehand selection tool to manually draw ROIs encompassing the cell trajectories suitable for downstream analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Use", "the", "freehand", "selection", "tool", ...
PMC11791264	Each bar represents the mean ± SD (n = 3).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Each", "bar", "represents", "the", "mean", "±", "SD", "(", "n", "=", ...
PMC6337547	Polyphenols are a class of important secondary metabolites with multiple phenolic hydroxyl groups, and include flavonoids, phenolic acids, stilbenes, and tannins (hydrolysable and condensed) , which are mainly synthesized by the phenylpropanoid metabolic pathway .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7823217	Bioprinted brain tumor constructs for drug screening/personalized treatment regimens can be particularly beneficial for glioblastoma (GBM), the brain tumor type that shows resistance to a number of chemotherapeutic agents .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11721064	Subsequently, the culture medium from P3 LNC cultures was collected and centrifuged at 12,000 rpm for 5 min, and the supernatant was designated as LNCs conditioned medium.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Primary endpoint is CR.	[ { "tags": [ "O", "O", "O", "O", "O" ], "tokens": [ "Primary", "endpoint", "is", "CR", "." ] } ]
PMC10907726	Fig. 6 Autophagy can be reversed by 3-MA. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fig.", "6", "Autophagy", "can", "be", "reversed", "by", "3-MA", ".", "(" ] } ]
PMC11543935	With respect to measuring the metabolic activity in the intended ablation area, located between the electrodes, a rectangular-shaped 3D-printed vacuum biopsy punch was used (See Fig. 1C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4816271	Therefore the incorporation of a mutation to prevent binding of high affinity FcγR avoids off target toxicity by the GD2-CAR. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", "the", ...
PMC11509309	Guanabenz, a drug used to treat hypertension, has been shown to exhibit both anti-prion activity and an ability to reduce UPR-induced cell death .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11786767	Biotin-DHPE signals are always present at the outer part of perichromosomal layer relative to the PS and Ki-67 signals.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Biotin-DHPE", "signals", "are", "...
PMC9792775	so the decrease of BCL-2 expression suggested that the infiltration of immune cells might be increased in the combination group, which further inhibited the tumor development.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11676674	As a result, cytotoxicity was assessed as part of the MN experiment in the same cells used to score micronuclei, using two separate methods: CN and cytostasis (CBPI%).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Methods: Ixa-Dara naïve RRMM patients received oral Ixazomib (4 mg: days 1, 8, 15), IV Daratumumab (16 mg/kg; days 1, 8, 15, 22, cycles 1-2; days 1, 15, cycles 3-6; days 1, cycles 7+) and IV Methylprednisolone before Daratumumab (100 mg at day 1, 8, cycle 1 and then 60 mg).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10729469	CD4+ CD25+ Tregs from different treatment groups were serially diluted in a U-bottom 96-well plate to obtain 50, 25, 12.5, and 6.25 × 10 Tregs in 100 µl of media followed by addition of 50 × 10 CFSE-labeled Tresp cells from non-Tg mice into each well to obtain Treg:Tresp ratios of 1:1, 0.5:1, 0.25:1 and 0.125:1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8633974	Primary human monocytes recovered after elutriation were plated on coverslips in 12 well plates.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Primary", "human", "monocytes", "recovered", "after", "elutriation", "...
PMC11742290	In summary, many studies have found that high LGR5 expression is associated with chemoresistance in breast, cervical, colorectal, hepatic, gastric and ovarian cancer to a wide range of chemotherapy drugs including carboplatin, cisplatin, paclitaxel oxaliplatin, 5-FU and doxorubicin.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10759659	a The different IL2, IL6, and IFN γ expression levels between the two groups.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "a", "The", "different", "IL2", ",", "IL6", ",", ...
PMC2193049	Based on this information, the prediction of putative antigenic peptides for defined MHC class I proteins has become possible.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Based", "on", "this", ...
PMC11401350	While PD-1 is known as inhibitory in immune cells, PD-1 plays an important role in Tfh development and activity .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "While", "PD-1", "is", ...
PMC11621493	The dyad is composed of the GXSXG motif and an aspartate (4).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "dyad", "is", "composed", "of", "the", "GXSXG", "motif", ...
PMC5415764	The accumulation of PTX in various treated cells was time-dependent (Fig. 3A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "accumulation", "of", "PTX", "in", "various", "treated", "...
PMC9429973	Results: Median follow up was 44 (11-55) months in group 1 and 60 (6-70) months in group 2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11680049	The diameter of the fungus was measured in two planes over time.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "diameter", "of", "the", "fungus", "was", "measured", "in", "two", "...
PMC9429973	Mean (standard deviation [SD]) percentage change in LDH from baseline to SC day 351 was 0.9% (20.5%).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11612794	The MS1 scan was collected at 60,000 resolution, the mass range 375 -1500 m/z, using a standard AGC and maximum injection time of 50 ms.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11407042	Transfer 100 μL overnight bacterial culture into a 50 mL tube containing 10 mL fresh LB medium.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Transfer", "100", "μL", "overnight", "bacterial",...
PMC11244823	Horse sera differentiated by ELISA gG1 results.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Horse", "sera", "differentiated", "by", "ELISA", "gG1", "results", "." ] } ]
PMC5716223	e Representative images (×40) of L6C5 cells grown in DM medium for 9 days with and without NGF (20 ng/ml).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "token...
PMC11467964	Thus, we explored the role of BMRGs in STS and tried to construct a novel predictive signature for STS prognosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thus", ",", "we",...
PMC11055443	Much evidence confirms that stimulation of MSCs with inflammatory signals like microbial products enhances their anti-inflammatory function.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Much", "evidence", "confirms", "that", "stimulati...
PMC11676674	Genotoxic substances can result in the development of micronuclei in cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Genotoxic", "substances", "can", "result", "in", "the", "development", "of", "micronuclei",...
PMC11543885	= 50 mM) and incubate in darkness for 30 min at 25°C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "=", "50", "mM", ")", "and", "incubate", "in", "darkne...
PMC11591038	Brain hypoxia induced by cerebral hypoperfusion or breathing 10% O2 triggered HIF-1α binding to γ-secretase to enhance its biological activity without affecting the expression level of individual subunits; further, the expression of full-length HIF-1α in primary neurons increased BACE1 expression and γ-secretase activi...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11597291	In brief, nCGO-PEG/PCT samples were enclosed in dialysis membranes (MWCO 12 kDa) and transferred to vials containing 20 mL PBS.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", ...
PMC11502443	The ability of the recently approved tirzepatide with the two endogenous forms of GIP, GIP(1-42) and GIP(1-30)NH2, to activate the WT human GIP receptor was compared for five signaling pathways, cAMP, IP1, AKT, ERK1/2, and CREB.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Image: Summary/Conclusion: Most of molecular alterations identified in PPCs seemed to be present in peripheral blood of patients with MM, surprisingly, even translocation breakpoints could be seen in cfDNA.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	80% of patients with TP53 aberration and 72% of patients with wt TP53 had at least 1 comorbidity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "80", "%", "of", "patie...
PMC10713411	The knockdown of TRIB3 decreased the proliferation potential, invasion capacity and colony formation ability of A498 cells and enhanced the apoptosis and autophagy process of A498 cells, which indicated that TRIB3 acted as a pro-tumor factor in RCC.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11406030	Immunofluorescence was performed as described previously.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Immunofluorescence", "was", "performed", "as", "described", "previously", "." ] } ]
PMC2944824	The level of caspase 3 activity in cultures from knockout mice was approximately two-fold higher than levels in wild-type cultures after treatment with staurosporine and over three-fold higher after treatment with thapsigargin.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11766350	rAAV yields of both the anti-gfp shRNA and scrambled control samples were lower than a gfp-only control sample indicating that even with shRNA-induced suppression, producing rAAV containing a cytotoxic transgene was not fully restored to the levels achieved when packaging a more benign cargo, i.e., gfp.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11576293	This study explores the synthesis of pyrimidine heterocycles 9–29.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "study", "explores", "the", "synthesis", "of", "pyrimidine", "heterocycles", "9–29", "." ] } ]
PMC7602170	Furthermore, it is helpful for predicting the malignant potential of GISTs as far as sensitivity and specificity is concerned .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Furthermore", ",", "it", ...
PMC6835428	In cultured A2780-ADR cells PEIPOS, 0.1%PEIPOS, and 0.5%PEIPOS loaded with PTX improved cytotoxicity.	[ { "tags": [ "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "cultured", "A2780-ADR", "cells", "PEIPOS", ",", ...
PMC10213179	In parallel, a cell-internalization SELEX was conducted to enrich for aptamers that selectively internalize into EphA2-expressing human cells (Figure 2A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", ...
PMC11566417	Then, the ‘gost’ function was applied to find GO term enrichment from the “GO:BP” source.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Then", ",", ...
PMC6133382	No adventitious agents were detected.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "No", "adventitious", "agents", "were", "detected", "." ] } ]
PMC9429973	Results: Between 4/2007 to 12/2019, 174 pts, with a median age of 51 years (range, 19-78) were included.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC7840816	Therefore, targeting the Wnt/β-catenin signaling cascade is a potential good therapeutic approach to PTC.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "targeting", "the", "Wnt/β-catenin", "signaling"...
PMC11088135	However, all these effects were reversed by YAP1-plasmid.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "all", "these", "effects", "were", "reversed", "by", "YAP1-plasmid", "." ] } ]
PMC11746942	These slides were then subjected to hematoxylin and eosin (H&E) staining for morphological analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "slides", "were", "then", "subjected", "to", ...
PMC9429973	Inclusion of observational studies was limited to those with >20 patients in the AZA monotherapy arm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Inclusion", "of", "observational", "studies", "wa...
PMC11680562	The observed release data highlights the crucial influence of the xanthan gum content in controlling the release of the medication from the gel matrix for all the gel formulations.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11774747	The need for a fast, efficient and safe treatment for early post-transplant viral infections prompted the generation of VST from third-party donors.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", ...
PMC11240052	The results demonstrated that miR-211-5p significantly decreased the luciferase activity of wild-type circ-0008285(WT), whereas miR-211-5p had no effect on mutant circ-0008285 (Mut) in SKOV3 and A2780 cells (P<0.0001) (Figure 3c, d).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9960565

BJ cells were cultured in D-MEM medium.

[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "BJ", "cells", "were", "cultured", "in", "D-MEM", "medium", "." ] } ]

PMC3681794

The introduction of dose intensive combination chemotherapy has increased the overall survival for osteosarcoma patients to over 70%. ,

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "introduction", "of", ...

PMC11740207

During gastrulation, EpibCs migrate into the embryo, giving rise to ectodermal progenitor cells (EcPCs), mesoderm progenitor cells (MdPCs), endodermal progenitor cells (EnPCs), and PGCs (Tam and Behringer, 1997).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11471176

A mixture of DMSO and media was used to dissolve the higher concentrations.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "mixture", "of", "DMSO", "and", "media", "was", "used", "to", ...

PMC11736898

Tissue samples from adults were collected as de-identified samples; this collection was designated as ‘not human subjects research’ by the UC IRB and therefore did not require informed consent.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11806613

10 luciferase (Luc)-expressing MDA-MB-231 cells were injected into the mammary fat pad of NSG mice (each group, n = 10).

[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC11727000

Secondary antibodies conjugated to HRP were purchased from Cell Signaling Technology.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Secondary", "antibodies", "conjugated", "to", "HRP", "were", "purchased", "from", "Cell", ...

PMC6835428

Additionally, tumor accumulation is modest for both methods, most likely due to passive targeting.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "tumor", "accumulation", "is", "mo...

PMC9429973

Image: Summary/Conclusion: In our series, 13.5 % of patients had a potential HMMS, being the incidence higher in those with a therapy-related neoplasm (30.7%).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

The limitation of the study is in the small numbers of the analysed population and the absent of the control comparative group.

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PMC9429973

Methods: We used mito-QC reporter mice and mitochondrial stain to analyze mitochondrial network upon in vitro treatment of metabolic modulator.

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PMC11021472

The fraction of the total RNA present in the cytoplasm (light grey, CF) and nucleus (dark grey, NF) is indicated.

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PMC11360263

Studies have demonstrated that the acquisition of EMT and stemness properties enhances the invasiveness and metastatic potential of cancer cells within tumors .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Studies", "h...

PMC9429973

EASIX [lactate dehydrogenase (U/L) x creatinine (mg/dl) / platelets (10/L)] and mEASIX [lactate dehydrogenase (U/L) x C reactive protein (CRP) (mg/dl) / platelets (10/L)] scores were calculated on days -7, 0, +3 and +7.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8348645

Table 1 given bellow mentions the sequence of the primers used.

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PMC11768281

T cells are critical players in the immune response to Plasmodium infection, with different subtypes contributing distinct roles at various stages of the disease.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...

PMC10891340

The mouse BCL2 like 13 is involved in CCCP-induced mitochondrial fragmentation and mitophagy through LIR-mediated LC3B binding (Murakawa et al., 2015).

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PMC11173119

The qPCR reactions for each sample were run in triplicate.

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PMC10335954

In the stomach, chronic inflammation from Helicobacter pylori infection accounts for about 90% of non-cardia GC cases (Plummer et al. 2015).

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PMC7081114

Univariate and multivariate analyses of disease-free survival in 186 patients with hepatocellular carcinoma P < 0.05 was considered significant, P < 0.05, P < 0.01.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11612794

Immunoprecipitation using anti-FLAG antibody in AID-based CENP-T conditional knockdown CENP-C/GFP-Dsn1 cells expressing 3xFLAG-CENP-T, 3xFLAG-CENP-T, or 3xFLAG-CENP-T. Cells were cultured with IAA for 12 h and nocodazole was added for last 10 h before immunoprecipitation experiments.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9872547

Curcumin can arrest the proliferation of cervical cancer cells depending on the time and concentration, and it is more active in HPV-infected cells.

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PMC11534035

Migration in A431 vulvar SCC cells is reduced in SERPINE1/PAI1 knockdown cells.

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PMC10529414

ChIP peaks (−q value 0.05) were called against the input-control sample from the filtered BAM files using the MACS2 peak caller.

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PMC9429973

5y OS was 64.3% (95% CI 44.9-83.7%), median OS 8.7years (95% CI 2.634 – 14.894).

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PMC11633763

ECAR of USP22‐overexpression U2OS cells transfected with shβ‐catenin. (

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PMC10955424

Malignant ascites untreated (n = 8), cirrhosis ascites (n = 3) and chemoresistance-inducing cirrhosis ascites (n = 1).

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PMC11194678

After 24–36 h, cells were fixed by 4% paraformaldehyde.

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PMC9325715

Iron stock solution with a concentration of ≈ 6 g/L was prepared from ammonium iron (III) citrate by dissolution in deionized water.

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PMC10577955

Non-small-cell lung carcinoma (NSCLC) is a type of epithelial lung cancer accounting for about 85% of all lung cancers.

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PMC11739504

Unexpectedly, the western blotting results indicated that the majority of IFT components decreased after 24 h of serum starvation, which is at the maturation stage of ciliogenesis, whereas the mRNA levels either increased slightly or remained unchanged (Fig. 3c and Supplementary Fig. 1b and d).

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PMC6461034

For lysis, use the same “lysis buffer” (already containing lysate from the first three dishes) from the labeled tube prepared in the previous step.

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PMC8494202

GSEA was used to analyze the potential cellular signaling pathways associated with CKAP2L.

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PMC11694346

This distribution further supports that the PET process from BT-NH to Cl-DNBS effectively quenches the dye's fluorescence.

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PMC11754436

lncRNAs can regulate the biological processes of numerous diseases, including cancer.

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PMC11733919

The iron phase (VFe–O) was retained after water transference.

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PMC11541409

Annals of Oncology, 2024; 10.1016/j.annonc.2024.08.2343.This reference is of outstanding importance because it clearly suggests that 6 years of imatinib treatment is better than 3 years of imatinib treatment in reducing recurrence of GIST.

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PMC11244823

The vaccinated horses were vastly over-represented in the gD1_83-positive group.

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PMC10936243

They were asked specifically about the relationship between bedding and post-operative pain in cats, and a variety of different answers emerged.

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PMC8701144

All of the reported protein identifications were statistically significant (p < 0.05) in Mascot and filtered in Proteome Discoverer Software (Thermo Fisher Scientific) for at least medium confidence identifications.

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PMC9429973

The primary endpoint is safety (incidence of dose limiting toxicities [DLTs]).

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PMC8316344

Iron absorption, transfer, storage, and retrieval are tightly regulated by numerous mechanisms .

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PMC9261184

This study provides the first measurement and modeling of total methane and CO2 emissions from an LNG carrier on a round trip voyage from the USA to Belgium and back, including loading, laden voyage, unloading, and ballast voyage, measuring emissions from exhaust stacks, vents, and fugitives.

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PMC7504302

Mechanistically, ALCAM enhanced the malignant features of mesothelioma cells and positively contributed to MPM progression.

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PMC11470381

Use the freehand selection tool to manually draw ROIs encompassing the cell trajectories suitable for downstream analysis.

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PMC11791264

Each bar represents the mean ± SD (n = 3).

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PMC6337547

Polyphenols are a class of important secondary metabolites with multiple phenolic hydroxyl groups, and include flavonoids, phenolic acids, stilbenes, and tannins (hydrolysable and condensed) , which are mainly synthesized by the phenylpropanoid metabolic pathway .

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PMC7823217

Bioprinted brain tumor constructs for drug screening/personalized treatment regimens can be particularly beneficial for glioblastoma (GBM), the brain tumor type that shows resistance to a number of chemotherapeutic agents .

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PMC11721064

Subsequently, the culture medium from P3 LNC cultures was collected and centrifuged at 12,000 rpm for 5 min, and the supernatant was designated as LNCs conditioned medium.

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PMC9429973

Primary endpoint is CR.

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PMC10907726

Fig. 6 Autophagy can be reversed by 3-MA. (

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PMC11543935

With respect to measuring the metabolic activity in the intended ablation area, located between the electrodes, a rectangular-shaped 3D-printed vacuum biopsy punch was used (See Fig. 1C).

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PMC4816271

Therefore the incorporation of a mutation to prevent binding of high affinity FcγR avoids off target toxicity by the GD2-CAR. (

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PMC11509309

Guanabenz, a drug used to treat hypertension, has been shown to exhibit both anti-prion activity and an ability to reduce UPR-induced cell death .

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PMC11786767

Biotin-DHPE signals are always present at the outer part of perichromosomal layer relative to the PS and Ki-67 signals.

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PMC9792775

so the decrease of BCL-2 expression suggested that the infiltration of immune cells might be increased in the combination group, which further inhibited the tumor development.

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PMC11676674

As a result, cytotoxicity was assessed as part of the MN experiment in the same cells used to score micronuclei, using two separate methods: CN and cytostasis (CBPI%).

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PMC9429973

Methods: Ixa-Dara naïve RRMM patients received oral Ixazomib (4 mg: days 1, 8, 15), IV Daratumumab (16 mg/kg; days 1, 8, 15, 22, cycles 1-2; days 1, 15, cycles 3-6; days 1, cycles 7+) and IV Methylprednisolone before Daratumumab (100 mg at day 1, 8, cycle 1 and then 60 mg).

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PMC10729469

CD4+ CD25+ Tregs from different treatment groups were serially diluted in a U-bottom 96-well plate to obtain 50, 25, 12.5, and 6.25 × 10 Tregs in 100 µl of media followed by addition of 50 × 10 CFSE-labeled Tresp cells from non-Tg mice into each well to obtain Treg:Tresp ratios of 1:1, 0.5:1, 0.25:1 and 0.125:1.

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PMC8633974

Primary human monocytes recovered after elutriation were plated on coverslips in 12 well plates.

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PMC11742290

In summary, many studies have found that high LGR5 expression is associated with chemoresistance in breast, cervical, colorectal, hepatic, gastric and ovarian cancer to a wide range of chemotherapy drugs including carboplatin, cisplatin, paclitaxel oxaliplatin, 5-FU and doxorubicin.

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PMC10759659

a The different IL2, IL6, and IFN γ expression levels between the two groups.

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PMC2193049

Based on this information, the prediction of putative antigenic peptides for defined MHC class I proteins has become possible.

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PMC11401350

While PD-1 is known as inhibitory in immune cells, PD-1 plays an important role in Tfh development and activity .

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PMC11621493

The dyad is composed of the GXSXG motif and an aspartate (4).

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PMC5415764

The accumulation of PTX in various treated cells was time-dependent (Fig. 3A).

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PMC9429973

Results: Median follow up was 44 (11-55) months in group 1 and 60 (6-70) months in group 2.

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PMC11680049

The diameter of the fungus was measured in two planes over time.

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PMC9429973

Mean (standard deviation [SD]) percentage change in LDH from baseline to SC day 351 was 0.9% (20.5%).

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PMC11612794

The MS1 scan was collected at 60,000 resolution, the mass range 375 -1500 m/z, using a standard AGC and maximum injection time of 50 ms.

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PMC11407042

Transfer 100 μL overnight bacterial culture into a 50 mL tube containing 10 mL fresh LB medium.

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PMC11244823

Horse sera differentiated by ELISA gG1 results.

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PMC5716223

e Representative images (×40) of L6C5 cells grown in DM medium for 9 days with and without NGF (20 ng/ml).

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PMC11467964

Thus, we explored the role of BMRGs in STS and tried to construct a novel predictive signature for STS prognosis.

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PMC11055443

Much evidence confirms that stimulation of MSCs with inflammatory signals like microbial products enhances their anti-inflammatory function.

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PMC11676674

Genotoxic substances can result in the development of micronuclei in cells.

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PMC11543885

= 50 mM) and incubate in darkness for 30 min at 25°C.

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PMC11591038

Brain hypoxia induced by cerebral hypoperfusion or breathing 10% O2 triggered HIF-1α binding to γ-secretase to enhance its biological activity without affecting the expression level of individual subunits; further, the expression of full-length HIF-1α in primary neurons increased BACE1 expression and γ-secretase activi...

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PMC11597291

In brief, nCGO-PEG/PCT samples were enclosed in dialysis membranes (MWCO 12 kDa) and transferred to vials containing 20 mL PBS.

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PMC11502443

The ability of the recently approved tirzepatide with the two endogenous forms of GIP, GIP(1-42) and GIP(1-30)NH2, to activate the WT human GIP receptor was compared for five signaling pathways, cAMP, IP1, AKT, ERK1/2, and CREB.

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PMC9429973

Image: Summary/Conclusion: Most of molecular alterations identified in PPCs seemed to be present in peripheral blood of patients with MM, surprisingly, even translocation breakpoints could be seen in cfDNA.

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PMC9429973

80% of patients with TP53 aberration and 72% of patients with wt TP53 had at least 1 comorbidity.

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PMC10713411

The knockdown of TRIB3 decreased the proliferation potential, invasion capacity and colony formation ability of A498 cells and enhanced the apoptosis and autophagy process of A498 cells, which indicated that TRIB3 acted as a pro-tumor factor in RCC.

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PMC11406030

Immunofluorescence was performed as described previously.

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PMC2944824

The level of caspase 3 activity in cultures from knockout mice was approximately two-fold higher than levels in wild-type cultures after treatment with staurosporine and over three-fold higher after treatment with thapsigargin.

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PMC11766350

rAAV yields of both the anti-gfp shRNA and scrambled control samples were lower than a gfp-only control sample indicating that even with shRNA-induced suppression, producing rAAV containing a cytotoxic transgene was not fully restored to the levels achieved when packaging a more benign cargo, i.e., gfp.

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PMC11576293

This study explores the synthesis of pyrimidine heterocycles 9–29.

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PMC7602170

Furthermore, it is helpful for predicting the malignant potential of GISTs as far as sensitivity and specificity is concerned .

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PMC6835428

In cultured A2780-ADR cells PEIPOS, 0.1%PEIPOS, and 0.5%PEIPOS loaded with PTX improved cytotoxicity.

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PMC10213179

In parallel, a cell-internalization SELEX was conducted to enrich for aptamers that selectively internalize into EphA2-expressing human cells (Figure 2A).

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PMC11566417

Then, the ‘gost’ function was applied to find GO term enrichment from the “GO:BP” source.

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PMC6133382

No adventitious agents were detected.

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PMC9429973

Results: Between 4/2007 to 12/2019, 174 pts, with a median age of 51 years (range, 19-78) were included.

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PMC7840816

Therefore, targeting the Wnt/β-catenin signaling cascade is a potential good therapeutic approach to PTC.

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PMC11088135

However, all these effects were reversed by YAP1-plasmid.

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PMC11746942

These slides were then subjected to hematoxylin and eosin (H&E) staining for morphological analysis.

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PMC9429973

Inclusion of observational studies was limited to those with >20 patients in the AZA monotherapy arm.

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PMC11680562

The observed release data highlights the crucial influence of the xanthan gum content in controlling the release of the medication from the gel matrix for all the gel formulations.

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PMC11774747

The need for a fast, efficient and safe treatment for early post-transplant viral infections prompted the generation of VST from third-party donors.

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PMC11240052

The results demonstrated that miR-211-5p significantly decreased the luciferase activity of wild-type circ-0008285(WT), whereas miR-211-5p had no effect on mutant circ-0008285 (Mut) in SKOV3 and A2780 cells (P<0.0001) (Figure 3c, d).

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