OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC11228511	P < 0.05 (n = 45 nuclei/group) compared to SMCs expressing prelamin A. (C) STED microscopy images of SMCs expressing prelamin A (Left) or progerin (Right) stained with antibodies against hu-lamin A (green) and lamin B1 (red). (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9884169	The 5637 cells treated with erastin (APExBIO) 2.5 μmol were gently scraped with a spatula, and the cell pellet was collected after centrifugation at 800 r. The collected cells were fixed in 2.5% and 1% glutaraldehyde (Servicebio, China).	[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11758416	Confirm under a microscope that cells are completely detached before proceeding.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Confirm", "under", "a", "microscope", "that", "cells", "are", "completely", "detached", ...
PMC11247842	Meta-analyses were performed using three approaches.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Meta-analyses", "were", "performed", "using", "three", "approaches", "." ] } ]
PMC9429973	Broviac and PICC remained without problems throughout the HSCT procedure in 91% (n=73) and 93% (n=39), respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9325715	Thus, makes it difficult to outline precisely which functional groups take part in the protein reactions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thus", ",", "makes", "it", "difficult", "to...
PMC11361748	Significant and comparable increases in TEWL values occur at 24 h and 48 h after a single TPA Tx (S1B Fig), suggesting that differences in the barrier status do not account for the difference seen in neutrophil infiltration when a repeat challenge is given at 48 h versus 24 h after the initial insult.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10798140	Many researchers have investigated various quinoline derivatives as potential anticancer drugs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Many", "researchers", "have", "investigated", "various", "quinoline", "derivatives", "as", ...
PMC10976516	Herbst et al.; Alexander et al.; Duma et al.ChemotherapyThese conditions may all be treated with chemotherapy:•as the primary treatment for those who are unable to undergo surgery•to relieve the pain of advanced cancer•to reduce the size of a tumor before surgery or radiation•to kill cancer cells that were not removed ...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9024365	not significant; **p < 0.01; one-way ANOVA with post-hoc Tukey’s test.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "not", "significant", ";", "", "", "p", "<", ...
PMC9919300	Palmitic acid (PA) and oleic acid (OA) dissolved in ethanol at 50 mM were used at the final concentrations 250 and 500 µM, respectively (1:2 ratio).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11509224	All of the isolated compounds were found to be inhibitors of cancer cell growth.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "of", "the", "isolated", "compounds", "were", "found", "to...
PMC10523483	Moreover, although studies have indicated a link between NRF2 and core histones, it remains unclear whether linker histones affect the level and activity of NRF2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10998613	First, a library of recombinant adenoviruses encoding 143 GPCRs fused with N-terminal fragments of yellow fluorescent protein, Venus (VN), and 147 GPCRs fused with C-terminal fragment of Venus (VC) was made as described in Song et al. (43).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7961460	They possess a karyotype with 55–60 chromosomes per cell with several rearrangements, they are positive for the carcinoembryonic antigen (CEA) and tissue polypeptide antigen (TPA) and negative for estrogen receptors mRNA.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11634027	Although Dachsous and Fat have been described as ligand and receptor, respectively, in a signal transduction pathway, there is also evidence for bidirectional signaling.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9275501	NDCDS of natural active ingredients and chemotherapy drugs also have advantages and limitations in tumor treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "NDCDS", "of", "natural", "active", "ingredients", "and...
PMC10729469	p < 0.05, p < 0.01, p < 0.001, ***p < 0.0001 Adoptive transfer of TCRAβ-Tregs increase Treg homing to brain and Treg function.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5600151	The uptake of TZ-DTX-dendrimer was 70% higher than that DTX-dendrimer after 4 h of incubation in the HER-positive cells, whereas no difference was observed between them in HER-negative ones.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11119602	They were then incubated with Alexa Fluor 546-labelled cisplatin (F-cisplatin; Molecular probes, Life Technologies, UK) at a final concentration of 200 U/mL (1 unit is defined as the reagent solution required to label 25 ng of DNA in vitro at 37 °C, for up to 48 h).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11513011	The rate of early apoptosis cells in T24 increased about 1.3 times by DIB compared to control, but there was no significant difference at the late stage (early: p = 0.0029).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8864075	In positive-ion mode, full-scan mass spectra were acquired over the m/z ratio from 350 to 1,800 using the Orbitrap mass analyzer with a mass resolution of 7,000.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC2614416	These findings can only mean that oxidoreductase enzymes are down-regulated in HepG2 cells, when compared to normal human liver. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "findi...
PMC11412721	Murine and human alternatively spliced p53 isoforms exhibit structural differences (Marcel et al., 2011) and the ChIP-Atlas database (Oki et al., 2018) does not report p53 binding to the human ACKR4 intron 1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11476106	Slides were kept in ethanol until staining.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Slides", "were", "kept", "in", "ethanol", "until", "staining", "." ] } ]
PMC9429973	No other grade 3-4 AEs were observed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "No", "other", "grade", "3", "-", "4", "AEs", "were", "observed", "." ] } ]
PMC11473843	Immunoblot for the indicated targets in A549 parental, VS4718-T and VS4718-T treated with XMD8-92 (10 μM).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Im...
PMC11725127	As shown in Fig. 3B, biotin-GA was effectively combined with the USP2 but not USP2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "As", "shown", "in", "Fig.", "3B", ",", "biotin-G...
PMC10957991	After 3 × 10 min wash, secondary antibodies together with phalloidin were incubated for 45 min, followed by 10–15 min incubation with DAPI for visualizing the nuclei.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11763111	However, as previously reported, 38BBz CAR-T cells exhibited limited proliferation and underwent apoptosis (Fig.S1A and B), probably because of CD38 expression in activated T cells .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10734950	The primary screening was at a concentration of 10 μM by differential nuclear staining assay (Z’ = 0.86) .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "primary", ...
PMC11173119	As a positive control for episomes (Episom+, Figure 1I), mononuclear cells harvested on the 6th day after transfection were used.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC5415764	To directly co-deliver multiple drugs in nanoparticles by one-step self-assembly or nanoprecipitation technology, several problems are usually encountered such as the random amount of loaded drug and low loading efficiency due to intermolecular interactions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	The only patient with grade III IRRs weighted 65 kg, did not have renal failure and did not receive montelukast premedication.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "only"...
PMC9024365	Last, the stratification of M4 and CT chimera puncta co-localized with SD1 results in a significant increase in the mean area of clusters (Figure 5D).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11323699	Our results shed new light in a context where the status of CD47 as a prognostic biomarker remains debated, notably due to the lack of clinical data.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9954564	The phased VCF file was converted into HLA-G CDS sequences by using the hg38 reference sequence as a draft and replacing the correct nucleotide at each position, two sequences per sample, using the application vcfx (function fasta) (www.castelli-lab.net/apps/vcfx (accessed on 1 October 2021)).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11628904	To confirm death of cells in zone 1, we examined this region 24 hpb and found nearly zero remaining keratinocytes regardless of treatment (Figure S1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11201989	Likewise, BBS5 could pull down GFP-PD-L1 and Myc-PC-2 (Figure 6D, E).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Likewise", ",", "BBS5", "could", "pull", "down", "GFP-PD-L1...
PMC11676674	As stated in the OECD guide, when at least one of the tested concentrations shows a statistically significant increase in comparison to the concurrent negative control under any of the experimental conditions, this can be considered a clear positive result for the tested substance.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11721064	Furthermore, RT-PCR and immunofluorescence staining identified the expression of ESC markers Oct4 and Sox2 in P3 LNCs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Furthermore", ",", "RT-PCR", "and", "i...
PMC11536589	AsPC1 cells were cultured in Roswell Park Memorial Institute (RPMI)-1640 medium, supplemented with 10% FBS and 1% P/S. The cell lines were grown at a temperature of 37 °C in a 5% CO2 humidified environment.	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9739791	One of the main advantages of the Pt(IV) prodrug approach is tuning their activity by varying the nature of the axial ligands .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "One", ...
PMC11269933	coli Transetta (DE3)Tsingke BiotechnologyCat#TSC-E01Chemicals, peptides, and recombinant proteinsPyruvate kinase assay kitCOMINCat#PK-1-YPyruvate (PA) assay kitCOMINCat#PA-1-YATP content assay kitCOMINCat#ATP-1-YGlucose uptake assay (Fluorometric, Direct Glucose)AbcamCar#ab234043Glycolysis Assay [Extracellular acidific...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11487720	We used the following WWOXf and WWOXd cell lines .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "used", "the", "following", "WWOXf", "and", "WWOXd", "cell", "lines", "." ] } ]
PMC11745823	The research utilised the glioma entire gene expression map database from the TCGA, providing genomic sequence data for five normal brain tissue (NBT) samples and 701 glioma tissue samples.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11023271	RIPK4, a serine-threonine kinase, plays critical roles in these processes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "RIPK4", ",", "a", "serine-threonine", "kinase", ",", "plays", "critical", "roles...
PMC10631132	Hematopoietic differentiation has been shown to require stages of mesodermal induction, hematoendothelial specification, vascular arterialization, endothelial-to-hematopoietic transition, and hematopoietic maturation .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11252033	To elucidate a possible interaction site of ASA within CryZ, two computational methods using molecular docking and fragment-mapping based approach were considered, taking advantage of the available crystal structure of the complex formed by CryZ with NADPH (PDB code: 1yb5).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8753818	In line with our findings, a series of Hashimoto and his colleagues’ data displayed that caspase-7 involved in the cell cycle regulation at mitotic phase.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11650848	LDtrait is an online tool used to identify LD associations to published phenotypes in the form of R or D’ values ranging from 0 (non-LD) to 1 (complete LD) .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11548041	Nanovesicles were then incubated with HuCCT1 cells, and the rate of internalization was assessed after four hours (Figure 5A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Nanovesicles", ...
PMC9429973	In patients with pathologic lung function tests age turned out to be significant for survival: 26 months (≥ 65 years) vs. not reached (< 65 years) (p = 0.008).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	In this group, 94% of pts had remission.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "this", "group", ",", "94", "%", "of", "pts", "had", "remission", "." ] } ]
PMC11089031	G The OE of ZNF692 promoted the migration of Caki-1 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "G", "The", "OE", "of", "ZNF692", "promoted", "the", "migration", "of", "Caki...
PMC11747885	In total 22 SGI-1027 derivatives were synthesized and tested, providing insights into the structural requirements for effective Rlig1 inhibition.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "total", "22", "S...
PMC9895440	RPMI with 8% human serum as described above and plated at 1.5 Mio/ml.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "RPMI", "with", "8", "%", "human", "serum", "as", "described", ...
PMC11697189	They facilitate tumor cell survival and proliferation by stabilizing carcinogenic proteins, inhibiting apoptosis signaling pathways, and maintaining protein folding and degradation balance.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11656048	p < 0.05, p < 0.01, *p < 0.001.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "p", "<", "0.05", ",", "", "", "p", "<", ...
PMC11521786	3LL-R3 cells were stained with anti-mErbB3 sera or with anti-HER3 sera.	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "3LL-R3", "cells", "were", "stained", "with", "anti-mErbB3", "sera", "or", "with", ...
PMC10213179	The gel was stained with ethidium bromide and visualized by UV exposure.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "gel", "was", "stained", "with", "ethidium", "bromide", "and", "visualized...
PMC9429973	Image: Summary/Conclusion: We generated an adult mouse model of lethal a-thal and, in preliminary experiments, we rescue it with ALS20a.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11769516	In the case of β-ZEL, significant changes in the cell cycle were observed at the two analyzed times—arrest or delay in the G2/M and S phases and activation of cell proliferation in the G0/G1 phase.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11377827	as (A) but HIF1β binding to specific HREs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "as", "(", "A", ")", "but", "HIF1β", "binding", "to", "specific", "HREs", "." ] } ]
PMC10589262	Because the surface expression of MT-KIT was low, twice the amount of biotin-labeled lysates was used for GIST cells than in CC cell lysates.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11632064	Ian Watson (McGill University).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Ian", "Watson", "(", "McGill", "University", ")", "." ] } ]
PMC11656380	PTEN loss hyperactivates the PI3K pathway, a key regulator of macropinocytosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "PTEN", "loss", "hyperactivates", "the", "PI3", "K", "pathway", ",", "...
PMC9429973	Summary/Conclusion: der(1;7)-positive MDS and AML represent a distinct subtype of myeloid neoplasms, characterized by unique patterns of co-mutations/copy-number lesions and gene expression profiles showing down-regulation of the cell-cycle pathway.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Aims: Describe cytogenetic landscape of patients diagnosed with acute myeloid leukemia treated in our center.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ":", "Describe", "cytogenetic", "landscape", "o...
PMC11723947	into sublethally-irradiated NSG mice with or without ex vivo expanded HLA-B7 human Treg.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "into", "sublethally-irradiated", "NSG", "mice", "with", "or", "without", "e...
PMC10810426	However, several other viruses, including HIV, have been shown to cause redistribution of NUPs to the cytoplasm (reviewed in ).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11574029	Thus, we investigated whether NOTCH3 could directly regulate SPP1 expression by binding to the CSL elements in its promoter.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thus", ",", "we", "inv...
PMC11766332	A number of CDG genes and/or ASD-risk genes, including DOLK, GALNT2, and EXT1, were identified as targets, along with validated interactions involving four key miRNAs (hsa-miR-423-5p, hsa-miR-30c-5p, hsa-miR-195-5p, and hsa-miR-132-5p).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Therefore, future studies should focus on the strategies which may help to alleviate these negative emotions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "future", "studies", "should", ...
PMC6222635	The DPFs F1 and F3 were the most effective.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "DPFs", "F1", "and", "F3", "were", "the", "most", "effective", "." ] } ]
PMC10993311	When HC, AC and length were compared repeatedly, there was an effect of time on HC [F(2;146) = 1279.33; p < 0.001], with T4>T3>T2 (p<0.001), on AC [F(2;146) = 872.45; p<0.001], with T4>T3>T2 (p<0.001), and on length [F(2;146) = 1144.72; p<0.001], with T4>T3>T2 (p<0.001).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	In the prior 12 months, regularly transfused adult and pediatric pts each received an average of about 10 transfusions whereas non-regularly transfused adult and pediatric pts received about 1 transfusion.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11767817	For 5637 cells, the IC50 values for curcumin were 12.7 ± 3.0 µM and 12.1 ± 0.2 µM for normoxic and hypoxic conditions, respectively .	[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4839679	The second strand of cDNA was synthesized using DNA polymerase and the double stranded cDNA was purified with magnetic beads.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "second", "strand", ...
PMC11434983	The membrane was then blocked for one hour in 5% non-fat dry milk in a TBST-T buffer (Tris-buffered saline and Tween 20).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC5839394	AO/EB staining technique was used to verify whether the AgNPs-EPS-cell death is due to apoptotic induction or unspecific necrosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "AO/EB", "staining", "technique", ...
PMC9429973	Results: Ten out of 17 centers referred pregnancies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", ":", "Ten", "out", "of", "17", "centers", "referred", "pregnancies", "." ] } ]
PMC11803149	Statistical analysis was performed using two-way RM ANOVA with uncorrected Fisher’s LSD test. ****	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Statistical", "analysis", "was", "performed"...
PMC11443022	In this case study, diagnostic procedures encompassed blood tests, semen analysis, chromosomal examination, and imaging studies to assess gonadal morphology.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC5963610	One representative experiment out of three performed experiments is shown in each case.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "One", "representative", "experiment", "out", "of", "three", "performed", "e...
PMC11679892	It has been shown that these molecules have the potential to suppress tumor proliferation, activate apoptosis mechanisms, and regulate oxidative stress levels .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11674834	Cells were plated at a density of 1 × 10 cells/well in 6-well plates and incubated for 24 h, after which media was replaced, and the cells were treated for 48 h with 3,4-DMA (5–25 µM) dissolved in DMSO or vehicle control (0.5% DMSO).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11787355	In a paired glioma and stromal cell scRNA-seq dataset (n(glioblastoma)=16, n(IDH-mut glioma)=3, and n(pediatric high-grade glioma)=1), we independently validated malignant cell-type specificity of PTPRZ1 expression (Fig. 1c, d, Supplementary Fig. 1i, j).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11496728	After transfection for 48 h, the medium was replaced with a DMEM/F12 complete medium containing puromycin (Beyotime, Shanghai, China) at a concentration of 16 µg/mL and changed every day for 5 days.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11796104	In conclusion, we emphasized the roles of several significantly up- and down-regulated DEcircRNAs and also identified three of the most widely covered miRNAs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973	A general linear mixed model was performed using SV as a continuous or a class variable (<6, 6–15, and >15 MN).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11612315	One-way ANOVA followed by Dunnett’s multiple comparison test (****p < 0.0001, compared with the control, CAP).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11794568	Transwell invasion assay to assess the invasive ability of CRIP1 overexpressing cutaneous melanoma cells (scale bar 50 μm). (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Transwell", "invasion",...
PMC11271278	N = 2 biological replicates.	[ { "tags": [ "O", "O", "O", "O", "O", "O" ], "tokens": [ "N", "=", "2", "biological", "replicates", "." ] } ]
PMC9884169	RNA (2 μg) was reverse transcribed into cDNA using reverse transcriptase (TIANGEN Biotech, China).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "RNA", "(", "2", "μg", ")", ...
PMC11707577	The ability of M13EGFR(TNP) to act as a photosensitizer in response to visible light exposure, was evaluated using the Amplex Red and ABMDMA assays.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11721064	Results indicated a 2.5-fold increase in p-STAT3 expression in LN-KS KPCs compared to control KPCs (p < 0.01).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", "indicated", "a", ...
PMC9917080	Only after 48 h did the proportion of cells appear in the early stages of apoptosis after pre-incubation with high doses of So.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Only", ...
PMC11731161	Through exporting several RNA-binding proteins and adaptor proteins, XPO1 is also responsible for transporting certain subsets of RNAs to the cytoplasm .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Through", "e...
PMC11701801	The cells were then reseeded again and incubated for 7 days.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cells", "were", "then", "reseeded", "again", "and", "incubated", "for", "7", ...

PMC11228511

P < 0.05 (n = 45 nuclei/group) compared to SMCs expressing prelamin A. (C) STED microscopy images of SMCs expressing prelamin A (Left) or progerin (Right) stained with antibodies against hu-lamin A (green) and lamin B1 (red). (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9884169

The 5637 cells treated with erastin (APExBIO) 2.5 μmol were gently scraped with a spatula, and the cell pellet was collected after centrifugation at 800 r. The collected cells were fixed in 2.5% and 1% glutaraldehyde (Servicebio, China).

[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11758416

Confirm under a microscope that cells are completely detached before proceeding.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Confirm", "under", "a", "microscope", "that", "cells", "are", "completely", "detached", ...

PMC11247842

Meta-analyses were performed using three approaches.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Meta-analyses", "were", "performed", "using", "three", "approaches", "." ] } ]

PMC9429973

Broviac and PICC remained without problems throughout the HSCT procedure in 91% (n=73) and 93% (n=39), respectively.

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PMC9325715

Thus, makes it difficult to outline precisely which functional groups take part in the protein reactions.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thus", ",", "makes", "it", "difficult", "to...

PMC11361748

Significant and comparable increases in TEWL values occur at 24 h and 48 h after a single TPA Tx (S1B Fig), suggesting that differences in the barrier status do not account for the difference seen in neutrophil infiltration when a repeat challenge is given at 48 h versus 24 h after the initial insult.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10798140

Many researchers have investigated various quinoline derivatives as potential anticancer drugs.

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PMC10976516

Herbst et al.; Alexander et al.; Duma et al.ChemotherapyThese conditions may all be treated with chemotherapy:•as the primary treatment for those who are unable to undergo surgery•to relieve the pain of advanced cancer•to reduce the size of a tumor before surgery or radiation•to kill cancer cells that were not removed ...

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PMC9024365

not significant; **p < 0.01; one-way ANOVA with post-hoc Tukey’s test.

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PMC9919300

Palmitic acid (PA) and oleic acid (OA) dissolved in ethanol at 50 mM were used at the final concentrations 250 and 500 µM, respectively (1:2 ratio).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11509224

All of the isolated compounds were found to be inhibitors of cancer cell growth.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "of", "the", "isolated", "compounds", "were", "found", "to...

PMC10523483

Moreover, although studies have indicated a link between NRF2 and core histones, it remains unclear whether linker histones affect the level and activity of NRF2.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10998613

First, a library of recombinant adenoviruses encoding 143 GPCRs fused with N-terminal fragments of yellow fluorescent protein, Venus (VN), and 147 GPCRs fused with C-terminal fragment of Venus (VC) was made as described in Song et al. (43).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC7961460

They possess a karyotype with 55–60 chromosomes per cell with several rearrangements, they are positive for the carcinoembryonic antigen (CEA) and tissue polypeptide antigen (TPA) and negative for estrogen receptors mRNA.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11634027

Although Dachsous and Fat have been described as ligand and receptor, respectively, in a signal transduction pathway, there is also evidence for bidirectional signaling.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9275501

NDCDS of natural active ingredients and chemotherapy drugs also have advantages and limitations in tumor treatment.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "NDCDS", "of", "natural", "active", "ingredients", "and...

PMC10729469

p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 Adoptive transfer of TCRAβ-Tregs increase Treg homing to brain and Treg function.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC5600151

The uptake of TZ-DTX-dendrimer was 70% higher than that DTX-dendrimer after 4 h of incubation in the HER-positive cells, whereas no difference was observed between them in HER-negative ones.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11119602

They were then incubated with Alexa Fluor 546-labelled cisplatin (F-cisplatin; Molecular probes, Life Technologies, UK) at a final concentration of 200 U/mL (1 unit is defined as the reagent solution required to label 25 ng of DNA in vitro at 37 °C, for up to 48 h).

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PMC11513011

The rate of early apoptosis cells in T24 increased about 1.3 times by DIB compared to control, but there was no significant difference at the late stage (early: p = 0.0029).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8864075

In positive-ion mode, full-scan mass spectra were acquired over the m/z ratio from 350 to 1,800 using the Orbitrap mass analyzer with a mass resolution of 7,000.

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PMC2614416

These findings can only mean that oxidoreductase enzymes are down-regulated in HepG2 cells, when compared to normal human liver. (

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PMC11412721

Murine and human alternatively spliced p53 isoforms exhibit structural differences (Marcel et al., 2011) and the ChIP-Atlas database (Oki et al., 2018) does not report p53 binding to the human ACKR4 intron 1.

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PMC11476106

Slides were kept in ethanol until staining.

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PMC9429973

No other grade 3-4 AEs were observed.

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PMC11473843

Immunoblot for the indicated targets in A549 parental, VS4718-T and VS4718-T treated with XMD8-92 (10 μM).

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PMC11725127

As shown in Fig. 3B, biotin-GA was effectively combined with the USP2 but not USP2.

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PMC10957991

After 3 × 10 min wash, secondary antibodies together with phalloidin were incubated for 45 min, followed by 10–15 min incubation with DAPI for visualizing the nuclei.

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PMC11763111

However, as previously reported, 38BBz CAR-T cells exhibited limited proliferation and underwent apoptosis (Fig.S1A and B), probably because of CD38 expression in activated T cells .

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PMC10734950

The primary screening was at a concentration of 10 μM by differential nuclear staining assay (Z’ = 0.86) .

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PMC11173119

As a positive control for episomes (Episom+, Figure 1I), mononuclear cells harvested on the 6th day after transfection were used.

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PMC5415764

To directly co-deliver multiple drugs in nanoparticles by one-step self-assembly or nanoprecipitation technology, several problems are usually encountered such as the random amount of loaded drug and low loading efficiency due to intermolecular interactions.

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PMC9429973

The only patient with grade III IRRs weighted 65 kg, did not have renal failure and did not receive montelukast premedication.

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PMC9024365

Last, the stratification of M4 and CT chimera puncta co-localized with SD1 results in a significant increase in the mean area of clusters (Figure 5D).

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PMC11323699

Our results shed new light in a context where the status of CD47 as a prognostic biomarker remains debated, notably due to the lack of clinical data.

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PMC9954564

The phased VCF file was converted into HLA-G CDS sequences by using the hg38 reference sequence as a draft and replacing the correct nucleotide at each position, two sequences per sample, using the application vcfx (function fasta) (www.castelli-lab.net/apps/vcfx (accessed on 1 October 2021)).

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PMC11628904

To confirm death of cells in zone 1, we examined this region 24 hpb and found nearly zero remaining keratinocytes regardless of treatment (Figure S1).

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PMC11201989

Likewise, BBS5 could pull down GFP-PD-L1 and Myc-PC-2 (Figure 6D, E).

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PMC11676674

As stated in the OECD guide, when at least one of the tested concentrations shows a statistically significant increase in comparison to the concurrent negative control under any of the experimental conditions, this can be considered a clear positive result for the tested substance.

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PMC11721064

Furthermore, RT-PCR and immunofluorescence staining identified the expression of ESC markers Oct4 and Sox2 in P3 LNCs.

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PMC11536589

AsPC1 cells were cultured in Roswell Park Memorial Institute (RPMI)-1640 medium, supplemented with 10% FBS and 1% P/S. The cell lines were grown at a temperature of 37 °C in a 5% CO2 humidified environment.

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PMC9739791

One of the main advantages of the Pt(IV) prodrug approach is tuning their activity by varying the nature of the axial ligands .

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PMC11269933

coli Transetta (DE3)Tsingke BiotechnologyCat#TSC-E01Chemicals, peptides, and recombinant proteinsPyruvate kinase assay kitCOMINCat#PK-1-YPyruvate (PA) assay kitCOMINCat#PA-1-YATP content assay kitCOMINCat#ATP-1-YGlucose uptake assay (Fluorometric, Direct Glucose)AbcamCar#ab234043Glycolysis Assay [Extracellular acidific...

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PMC11487720

We used the following WWOXf and WWOXd cell lines .

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PMC11745823

The research utilised the glioma entire gene expression map database from the TCGA, providing genomic sequence data for five normal brain tissue (NBT) samples and 701 glioma tissue samples.

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PMC11023271

RIPK4, a serine-threonine kinase, plays critical roles in these processes.

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PMC10631132

Hematopoietic differentiation has been shown to require stages of mesodermal induction, hematoendothelial specification, vascular arterialization, endothelial-to-hematopoietic transition, and hematopoietic maturation .

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PMC11252033

To elucidate a possible interaction site of ASA within CryZ, two computational methods using molecular docking and fragment-mapping based approach were considered, taking advantage of the available crystal structure of the complex formed by CryZ with NADPH (PDB code: 1yb5).

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PMC8753818

In line with our findings, a series of Hashimoto and his colleagues’ data displayed that caspase-7 involved in the cell cycle regulation at mitotic phase.

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PMC11650848

LDtrait is an online tool used to identify LD associations to published phenotypes in the form of R or D’ values ranging from 0 (non-LD) to 1 (complete LD) .

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PMC11548041

Nanovesicles were then incubated with HuCCT1 cells, and the rate of internalization was assessed after four hours (Figure 5A).

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PMC9429973

In patients with pathologic lung function tests age turned out to be significant for survival: 26 months (≥ 65 years) vs. not reached (< 65 years) (p = 0.008).

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PMC9429973

In this group, 94% of pts had remission.

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PMC11089031

G The OE of ZNF692 promoted the migration of Caki-1 cells.

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PMC11747885

In total 22 SGI-1027 derivatives were synthesized and tested, providing insights into the structural requirements for effective Rlig1 inhibition.

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PMC9895440

RPMI with 8% human serum as described above and plated at 1.5 Mio/ml.

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PMC11697189

They facilitate tumor cell survival and proliferation by stabilizing carcinogenic proteins, inhibiting apoptosis signaling pathways, and maintaining protein folding and degradation balance.

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PMC11656048

p < 0.05, **p < 0.01, ***p < 0.001.

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PMC11521786

3LL-R3 cells were stained with anti-mErbB3 sera or with anti-HER3 sera.

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PMC10213179

The gel was stained with ethidium bromide and visualized by UV exposure.

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PMC9429973

Image: Summary/Conclusion: We generated an adult mouse model of lethal a-thal and, in preliminary experiments, we rescue it with ALS20a.

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PMC11769516

In the case of β-ZEL, significant changes in the cell cycle were observed at the two analyzed times—arrest or delay in the G2/M and S phases and activation of cell proliferation in the G0/G1 phase.

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PMC11377827

as (A) but HIF1β binding to specific HREs.

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PMC10589262

Because the surface expression of MT-KIT was low, twice the amount of biotin-labeled lysates was used for GIST cells than in CC cell lysates.

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PMC11632064

Ian Watson (McGill University).

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PMC11656380

PTEN loss hyperactivates the PI3K pathway, a key regulator of macropinocytosis.

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PMC9429973

Summary/Conclusion: der(1;7)-positive MDS and AML represent a distinct subtype of myeloid neoplasms, characterized by unique patterns of co-mutations/copy-number lesions and gene expression profiles showing down-regulation of the cell-cycle pathway.

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PMC9429973

Aims: Describe cytogenetic landscape of patients diagnosed with acute myeloid leukemia treated in our center.

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PMC11723947

into sublethally-irradiated NSG mice with or without ex vivo expanded HLA-B7 human Treg.

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PMC10810426

However, several other viruses, including HIV, have been shown to cause redistribution of NUPs to the cytoplasm (reviewed in ).

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PMC11574029

Thus, we investigated whether NOTCH3 could directly regulate SPP1 expression by binding to the CSL elements in its promoter.

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PMC11766332

A number of CDG genes and/or ASD-risk genes, including DOLK, GALNT2, and EXT1, were identified as targets, along with validated interactions involving four key miRNAs (hsa-miR-423-5p, hsa-miR-30c-5p, hsa-miR-195-5p, and hsa-miR-132-5p).

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PMC9429973

Therefore, future studies should focus on the strategies which may help to alleviate these negative emotions.

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PMC6222635

The DPFs F1 and F3 were the most effective.

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PMC10993311

When HC, AC and length were compared repeatedly, there was an effect of time on HC [F(2;146) = 1279.33; p < 0.001], with T4>T3>T2 (p<0.001), on AC [F(2;146) = 872.45; p<0.001], with T4>T3>T2 (p<0.001), and on length [F(2;146) = 1144.72; p<0.001], with T4>T3>T2 (p<0.001).

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PMC9429973

In the prior 12 months, regularly transfused adult and pediatric pts each received an average of about 10 transfusions whereas non-regularly transfused adult and pediatric pts received about 1 transfusion.

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PMC11767817

For 5637 cells, the IC50 values for curcumin were 12.7 ± 3.0 µM and 12.1 ± 0.2 µM for normoxic and hypoxic conditions, respectively .

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PMC4839679

The second strand of cDNA was synthesized using DNA polymerase and the double stranded cDNA was purified with magnetic beads.

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PMC11434983

The membrane was then blocked for one hour in 5% non-fat dry milk in a TBST-T buffer (Tris-buffered saline and Tween 20).

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PMC5839394

AO/EB staining technique was used to verify whether the AgNPs-EPS-cell death is due to apoptotic induction or unspecific necrosis.

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PMC9429973

Results: Ten out of 17 centers referred pregnancies.

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PMC11803149

Statistical analysis was performed using two-way RM ANOVA with uncorrected Fisher’s LSD test. ****

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PMC11443022

In this case study, diagnostic procedures encompassed blood tests, semen analysis, chromosomal examination, and imaging studies to assess gonadal morphology.

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PMC5963610

One representative experiment out of three performed experiments is shown in each case.

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PMC11679892

It has been shown that these molecules have the potential to suppress tumor proliferation, activate apoptosis mechanisms, and regulate oxidative stress levels .

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PMC11674834

Cells were plated at a density of 1 × 10 cells/well in 6-well plates and incubated for 24 h, after which media was replaced, and the cells were treated for 48 h with 3,4-DMA (5–25 µM) dissolved in DMSO or vehicle control (0.5% DMSO).

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PMC11787355

In a paired glioma and stromal cell scRNA-seq dataset (n(glioblastoma)=16, n(IDH-mut glioma)=3, and n(pediatric high-grade glioma)=1), we independently validated malignant cell-type specificity of PTPRZ1 expression (Fig. 1c, d, Supplementary Fig. 1i, j).

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PMC11496728

After transfection for 48 h, the medium was replaced with a DMEM/F12 complete medium containing puromycin (Beyotime, Shanghai, China) at a concentration of 16 µg/mL and changed every day for 5 days.

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PMC11796104

In conclusion, we emphasized the roles of several significantly up- and down-regulated DEcircRNAs and also identified three of the most widely covered miRNAs.

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PMC9429973

A general linear mixed model was performed using SV as a continuous or a class variable (<6, 6–15, and >15 MN).

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PMC11612315

One-way ANOVA followed by Dunnett’s multiple comparison test (****p < 0.0001, compared with the control, CAP).

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PMC11794568

Transwell invasion assay to assess the invasive ability of CRIP1 overexpressing cutaneous melanoma cells (scale bar 50 μm). (

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PMC11271278

N = 2 biological replicates.

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PMC9884169

RNA (2 μg) was reverse transcribed into cDNA using reverse transcriptase (TIANGEN Biotech, China).

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PMC11707577

The ability of M13EGFR(TNP) to act as a photosensitizer in response to visible light exposure, was evaluated using the Amplex Red and ABMDMA assays.

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PMC11721064

Results indicated a 2.5-fold increase in p-STAT3 expression in LN-KS KPCs compared to control KPCs (p < 0.01).

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PMC9917080

Only after 48 h did the proportion of cells appear in the early stages of apoptosis after pre-incubation with high doses of So.

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PMC11731161

Through exporting several RNA-binding proteins and adaptor proteins, XPO1 is also responsible for transporting certain subsets of RNAs to the cytoplasm .

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PMC11701801

The cells were then reseeded again and incubated for 7 days.

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