OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC11502962	The two tumors were both located on the greater curvature of the gastric body.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "two", "tumors", "were", "both", "located", "on", "the", ...
PMC11740508	F Representative fluorescence images of p-H2A.X staining with talazoparib + decitabine treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "F", "Representative", "fluorescence", "images", "of", "p-H2A.X", "staining", "with", ...
PMC8633974	Virions were produced by transfecting mutated NL4-3 plasmids in HEK293FT cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "Virions", "were", "produced", "by", "transfecting", "mutated", "NL4", ...
PMC11046454	After incubation with FITC-CEM, the expression level of CD25 and CD69, two T cell activation markers, on CAR-J was significantly enhanced, showing a positive correlation with the surface density of the FITC moiety (Figures 1F and S9).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11496728	At present, most recombinant protein drugs are produced in CHO cell lines, because of their safety in humans, biosimilar glycosylation patterns, kinetic systems for gene amplification, and simple adaptability in suspension.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3164356	This lack of expression of integrin genes in CHO cells has been documented previously.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "lack", "of", "expression", "of", "integrin", "genes",...
PMC11657695	Currents were generated by stepwise 10 mV depolarizing pulses (500 ms duration; 4 ms intervals) from a constant holding potential of −70 mV from −90 mV to + 90 mV. E Upper panels: Current density–voltage relationships obtained in 10 A-673 cells before and after application of κ-Cono.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11216402	Here we use ATAC-seq and RNA-seq data from a compendium of GC cell lines and primary tumors to detect drivers of regulatory state changes and their transcriptional responses.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11774112	The tissues of the tumor, heart, liver, spleen, lung, and kidney were collected and stored in 4% paraformaldehyde overnight, which were then stained with hematoxylin and eosin (H&E).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9473868	The imbalance of FLS proliferation and apoptosis has been considered as an initiation factor in RA development .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "imbalance", "of", "FLS", "proliferation", ...
PMC11587541	Understanding how telomeres are affected in SMA can provide valuable insights into the disease process and may lead to the development of targeted therapies aimed at preserving telomere length and improving outcomes for SMA patients.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Then the MENK was added to kill the tumor formed within the femur.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Then", "the", "MENK", "was", "added", "to", "kill", "the", "tumor", ...
PMC11742047	Heatmaps depicting glycerophospholipids changes associated with CBD treatment observed in LC–MS (+).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Heatmaps", "depicting", "glycerophospholipids", "changes", "...
PMC11705547	Preclinical studies have shown that cisplatin promotes exosome secretion by the CAFs, which can inhibit ferroptosis in gastric cancer cells by reducing the accumulation of lipid-ROS, resulting in increased resistance to cisplatin .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8956657	no significance; ****p < 0.0001.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "no", "significance", ";", "", "", "", "", "p", "<", "0.0001", "." ] } ]
PMC11513011	DIB significantly suppressed wound healing in KK-47, T24, and 5637 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "DIB", "significantly", "suppressed", "wound", "healing", "in...
PMC9429973	Aims: We aimed to characterize the cellular composition and transcriptional alterations occurring in peripheral blood (PB) obtained from MF pts enrolled in the MANIFEST trial.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10440586	We validate the prognosis value of CD99 in glioma in multiple datasets.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "validate", "the", "prognosis", "value", "of", "CD99", "in", "glioma", ...
PMC9444294	ChIP was performed using 10 µg of chromatin and 2 µg of antibody (Active Motif, #53009, Carlsbad, CA, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11188874	After drug treatment, E.G7-Ova cells were incubated with B3Z cells at an E:T ratio of 2:1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "drug", "treatment", ",",...
PMC9430052	All pts presented with Ann Arbor stage IV disease.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "pts", "presented", "with", "Ann", "Arbor", "stage", "IV", "disease", "." ] } ]
PMC6379402	Then, the probability of connecting two nodes is equal to the product of their stickiness indexes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Then", ",", "the", "probability", "of", "co...
PMC11657695	3KCNA2 expression is regulated by the chimeric protein EWS::FLI1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "3KCNA2", "expression", "is", "regulated", "by", "the", "chimeric", "protein", "EWS::FLI1", "." ] } ]
PMC8557138	Nagy et al. reported the presence of six morphologically and functionally distinct tumor vessel subtypes including mother vessels, capillaries, glomeruloid microvascular proliferations, vascular malformations, feeder arteries, and draining veins; of which two of the vessel forms were capable of surviving in the absence...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6160470	We have previously developed a computational model, which enabled us to synthesise novel 18-crown-6 ether compounds.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "have", "previously", "developed", "a", ...
PMC7887261	Study participants were genotyped on an Axiom Exome Plus Array (Affymetrix), which contains a custom panel of key LC GWAS markers, and rare coding SNVs and indels.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11322866	The solid lines indicate direct interactions, while the dashed lines indicate potential interactions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "solid", "lines", "indicate", "direct", "interactions", ",", ...
PMC9429973	Methods: We analyzed internal trial matrix database and examined other documents such as laboratory specification documents, trial design, protocol, and schedule of activities.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Patients were required to have at least one record of receiving both a cBTKi and a BCL2i.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Patients", "were", "required", "to", "have", ...
PMC8903741	The antigen-binding efficiency of each antibody differed because the characteristics of each antibody from mammalian cell expressions, such as post-translational modification including glycosylation, folding, and assembly might vary.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8662250	Immunoblot analysis revealed that CBD was able to reduce all the analyzed proinflammatory markers triggered by SP incubation, such as tool‐like receptor 4 (TLR‐4), ACE‐2, family members of Ras homologues A‐GTPase (RhoA‐GTPase), inflammasome complex (NLRP3), and Caspase‐1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11496728	Normal cells without a transfection plasmid died.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Normal", "cells", "without", "a", "transfection", "plasmid", "died", "." ] } ]
PMC11621493	B–D) Gene set enrichment plots of GO molecular function gene sets “Cytokine activity” and “chemokine activity,” as well as the GO biological process gene set “lipid catabolic process” comparing KO and WT cells in the absence of IL17A and TNFα (basal).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11683130	There is evidence that RNA silencing of SerpinB2 in keratinocytes leads to upregulation of IL-8, CXCL5 and CCL5 and increased neutrophil migration (117).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11055323	After 10 days, cells were fixed in 4% paraformaldehyde (Sangon, E672002-0500) for 20 min at room temperature and then stained with crystal violet (Beyotime, C0121-100 ml) for 10 min at room temperature.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9436459	Therefore, the use of bromine substituted substrates in these reactions would give a better combined yield of diene S46.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "the", ...
PMC11518702	In chamber migration assays (using fibronectin), endogenous and ectopic expression of HGAL in IgM-stimulated *U2932 or Bjab cells (respectively) significantly attenuated SDF1-induced cell migration (55).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "...
PMC10808409	Bar chart showing percentage of cell population in each phase of the cell cycle analysis. *	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Bar", "chart", "showing", "percentage", "of", "cell", ...
PMC11750165	The gain-of-function study using Tg[hsp70-Mib:EGFP] showed that the majority of cells in the p3 domain differentiated into KA” neurons after heat-shock during late neurogenesis (Ryu et al., 2015).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11046454	AptPTK7-induced specific contact between CAR-T and PTK7 K562 was first confirmed with flow cytometry (Figure 2G).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "AptPTK7-induced", "specific", ...
PMC11507371	Studies have shown that ROS-inducing therapies are an effective anti-cancer strategy by increasing ROS levels.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Studies", "have", "shown", "that", "ROS-inducing", "therapies", ...
PMC9848491	The infiltration scores of 16 immune cells and the activities of 13 immune-related functions were calculated by single-sample gene set enrichment analysis (ssGSEA) using the “GSVA” package.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11307990	In this study, we fabricated precisely structured DNA nanotapes with strong surface SUN adhesion, enabling RTK inhibition of renal clear carcinoma cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11583690	Fig. 6A shows that free DTX, nanoparticles, and DTX-loaded nanoparticles have mild toxicity on Hs68 cells, with the percentage of viable cells decreasing gradually with increasing concentrations, although not significantly.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11742431	For example, Hu et al. inhibited Survivin expression at the transcriptional and protein levels to suppress tumor growth in tumor‐bearing mice.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "examp...
PMC11502443	Comparison of each peptide’s ability to induce signaling for different pathways at the WT GIP receptor. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Comparison", "of", "each", "peptide", ...
PMC11680562	Additionally, immediate skin sensation was carefully evaluated, encompassing stiffness, grittiness, and greasiness .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "immediate", "skin", "sensation", ...
PMC9429973	Aims: This presentation provides an overview of EFG as a molecule and summarize the clinical development program to date.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ":", "This", "p...
PMC11696576	An alternative route for the construction of the thiazolyl ring was also explored, in case of lack of commercially available TBDMSCN.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "An", "altern...
PMC10482220	In cells subjected to arsenite stress, the CD mutant was recruited to SGs (in 86% of transfected cells).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "cells"...
PMC8633974	Statistical differences between unstimulated compared to stimulated RT activity values and stimulated control compared to stimulated treatment RT activity values were calculated with two-way ANOVA followed by Sidak's post-hoc test for multiple comparisons.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11673902	The constriction channels can simulate the environment of capillaries in the body.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "constriction", "channels", "can", "simulate", "the", "environment", "of", ...
PMC11703992	IL-6 expression has downregulations in the DDIT4-OE group and TNF-α expression has upregulations in the DDIT4-KD group.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "IL-6", "expression", "has", "downregulations", "i...
PMC9429973	For pathway inhibition specific compounds as well as shRNA-mediated knockdown were used for functional read-out of ADCP and viability in lymphoma co-culture.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "pathw...
PMC11488203	Lipofectamine RNAiMAX reagent was obtained from Gibco/Life Technologies GmbH, Darmstadt, Germany.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Lipofectamine", "RNAiMAX", "reagent", "was", "obtained", "from", "Gibco/Life", ...
PMC11323699	Fig. 4).	[ { "tags": [ "O", "O", "O", "O" ], "tokens": [ "Fig.", "4", ")", "." ] } ]
PMC11738017	Meanwhile, the emergence of antigen escape clones represents a recurrent mechanism of secondary resistance to anti-BCMA chimeric antigen receptor T-cell (CAR T) or TCE therapy.10, 11, 12, 13 BCMA antigen escape occurs through biallelic deletions of TNFRSF17 or monoallelic deletion, coupled with BCMA extracellular domai...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3813807	This showed that, in grades I, II and III gastric adenocarcinoma tissues, the upregulation of miR-373 was more marked than that in 15 matched normal tissues, while the mRNA levels of TNFAIP1 in all investigated gastric adenocarcinoma tissues were lower than those in matched normal tissues (Fig. 3A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Aims: In this study, we investigated the role of EASIX and mEASIX scores in the prediction of transplant related complications and survival in patients undergoing allogeneic hematopoietic stem cell transplantation (alloHCT).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	AMH is considered to be the most sensitive biomarker for gonadal reserve (decreasing values correlate with ovarian insufficiency).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "AMH", "is", "considered", ...
PMC9398137	A subset of DLBCL and majority of Burkitt lymphoma cell lines were sensitive to S63845.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "I-CellLine", "I-CellLine", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "subset", "of", "DLBCL", "and", "m...
PMC10203589	In the diagnosis of pheochromocytoma (PCC) and paraganglioma (PGL) (172–174).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "the", "diagnosis", "of", "pheochromocytoma", "("...
PMC11682224	Under hypoxic conditions, CHD1L promoted the proliferation, migration, invasion, and angiogenesis of cutaneous squamous cell carcinoma.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Under", "hypoxic", "conditio...
PMC11218145	Y-axis shows, relative to the controls, the absorbance at 595 nm obtained with the MTT assay as a proxy of the cell viability, and expressed as relative absorbance “RA”.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11470999	Moreover, knockdown of CIP2A markedly decreased melanoma cells' sensitivity to PF (Figure 4E,F).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "knockdown", "of"...
PMC11721295	We defined ligand-receptor pairs based on a curated, literature-supported list described by Ramilowski et al. (36) and further curated by Steele et al. (37).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11615743	Our work presents a proof of principle for the isolation of target cells using an L‐DNA‐based logic gate under optimal conditions for cell growth to minimize damage to cells caused by previous methods, which are typically conducted in an FBS‐free buffer.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11095939	It has been well documented that both overexpression and depletion of Mecp2 have deleterious effects on neuronal homeostasis (Na et al., 2013), and thus, tight regulation of Mecp2 protein levels is critical for its physiological functions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11637716	This is further complicated by the fact that at the somatic level, there may be spontaneous genetic alterations which modify the expected phenotype, as recently exemplified by a loss of heterozygosity in favour of the ‘milder’ of the two variants in a subset of blood cells from a patient with EFL1‐associated SDS.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11763126	G H&E staining assessing metastasis levels in lung tissues.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "G", "H&E", "staining", "assessing", "metastasis", "levels", "in", "lung", "tissues", "." ] } ]
PMC11756937	Afterwards, the vial containing the cells was dried, dowsed with 70% ethanol and wiped dry again prior to placing it into the hood.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11321678	Subgroup‐specific TFs are identified and visualized on UMAP (Figure 3B).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Subgroup‐specific", "TFs", "are", "identified", "and", "visualized", "on", "UMAP", ...
PMC10976516	Thus, tumor vasculature is an appealing element of tumor biology to target OV infection.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Thus", ",", "tumor", "vasculature", "is", "an", "appealing"...
PMC11286266	Normalised cell lysates (15–30 μg) were loaded as an ‘input’ control.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Normalised", "cell", "lysates", "(", "15–30", "μg", ")", ...
PMC11765988	Sarcoidosis is characterized by non-caseating granulomas composed of epithelioid cells, whereas lymphomatous nodes primarily consist of lymphocytes and Reed-Sternberg cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Sarcoidosis", "is", ...
PMC11258145	Utilizing the Behrens method, the median lethal dose (LD50) was determined from the data presented.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Utilizing", "the", "Behrens", "method", ...
PMC11628309	A clear example is the use of 6-OHDA, a dopaminergic analog that is taken up into the cell through DAT (Hernandez-Baltazar et al., 2017).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11566417	Specifically, work in the bovine model has shown that the secretome of adult mammary stem/progenitor cells confers antimicrobial, regenerative, and immunomodulatory properties in vitro .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	One way ANOVA test was used to compare continuous variables.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "One", "way", "ANOVA", "test", "was", "used", "to", "compare", "continuous", "variables", "...
PMC9985266	Increasing evidence shows that long noncoding RNAs (lncRNAs) have an important influence on PF .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Increasing", "evidence", "shows", "that", "long", "non...
PMC10926885	We obtained the GSEA database and ran KEGG and GO enrichment analyses of NDE1 to learn more about the role that NDE1 plays in the immune regulation of cancer.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8956657	Each exhibit highly similar binding mechanisms that, in both cases, lack a prototypical Lys bound at their P2 site.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Each", "exhibit", ...
PMC9429973	Summary/Conclusion: PET/CT is a valuable tool for response assessment in PMBCL after R-da-EPOCH, facilitating clinical decision making regarding further consolidative RT, which can be minimized.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8839885	2HE2 is considered a prodrug of 2ME2 since the conversion of 2HE2 to 2ME2 is very efficient .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "2HE2", "is", "considered", "a", "prodrug", ...
PMC11791203	Fig. 8(A) Three dimensional docking interaction images of 1,2-benzenedicarboxylic acid, Cyclododecanol, 2,4-Ditert-Butylphenol and Sulfurous acid, hexyl octyl ester onto Cox-2. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11216402	We used RNA-seq data from the 25 GC cell lines to understand how the differential TF activity inferred from the ATAC-seq data affects gene expression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10565698	H–K. Transwell migration (H and I) and invasion (J and K) assays with HCCLM3 and BEL-7407 cells following miR-211-5p mimic transfection. *:	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "...
PMC9080589	We observed that the activation of Wnt signaling by LiCl treatment impaired the inhibitory effects of PCDH8 on the proliferation (Fig. 5C), metastasis (Fig. 5D) and apoptosis (Fig. 5E) of TPC-1 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11629143	Flow cytometry analysis for eGFP reporter assays used an LX375 CytoFLEX flow cytometer (Beckman Coulter).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Flow", "cytometry", "analysis", "for", "eGFP", ...
PMC10728200	Among the 418 included patients, 397 patients (95.0%) were followed up completely and 21 were lost to follow-up.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Among", "the...
PMC10998613	This suggests that there was no significant heterodimerization between the receptors in this cell line.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "suggests", "that", "there", "was", "no", "significa...
PMC10988808	As a receptor for NETs, it may be associated with liver metastasis of tumors [16–18].	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "As", "a", "receptor", "for", "NETs", ...
PMC11599565	Interestingly, the inhibition of MAP4K4 and Notch pathways induces the upregulation of both βIII-tubulin and ChgA, two classical neuronal markers.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Interestingly", ...
PMC10291556	The reaction products were analyzed by HPLC.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "reaction", "products", "were", "analyzed", "by", "HPLC", "." ] } ]
PMC11349530	The reason for this may be that above-mentioned therapies usually target only one factor, whereas many factors are involved in tumorigenesis and cancer-related inflammation (110).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10507284	After eliminating patients without survival information, a total of 263 STS patients were enrolled for further analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "eliminating", "patients", "without"...
PMC11704834	As demonstrated in Fig. 4Cb, acute ablation of TLE1 expression in A549GR cells partially restored their sensitivity to gefitinib-induced apoptosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "As", "demonstr...
PMC11680391	However, the perspectives of the dairy farmer and the dairy veterinarian still differ because their starting point for conversation differs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "However", ",", "t...
PMC9429973	HCRU and costs (adjusted to 2019 US dollars) associated with induction and post-remission therapy were assessed during a treatment cycle.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "HCRU", "and"...
PMC11682172	We only found coronin-1A to be upregulated following T lymphocyte contact while the expression of its family members coronin-1B, coronin 1C and coronin 7 remained unaffected.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11502962

The two tumors were both located on the greater curvature of the gastric body.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "two", "tumors", "were", "both", "located", "on", "the", ...

PMC11740508

F Representative fluorescence images of p-H2A.X staining with talazoparib + decitabine treatment.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "F", "Representative", "fluorescence", "images", "of", "p-H2A.X", "staining", "with", ...

PMC8633974

Virions were produced by transfecting mutated NL4-3 plasmids in HEK293FT cells.

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PMC11046454

After incubation with FITC-CEM, the expression level of CD25 and CD69, two T cell activation markers, on CAR-J was significantly enhanced, showing a positive correlation with the surface density of the FITC moiety (Figures 1F and S9).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11496728

At present, most recombinant protein drugs are produced in CHO cell lines, because of their safety in humans, biosimilar glycosylation patterns, kinetic systems for gene amplification, and simple adaptability in suspension.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC3164356

This lack of expression of integrin genes in CHO cells has been documented previously.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "lack", "of", "expression", "of", "integrin", "genes",...

PMC11657695

Currents were generated by stepwise 10 mV depolarizing pulses (500 ms duration; 4 ms intervals) from a constant holding potential of −70 mV from −90 mV to + 90 mV. E Upper panels: Current density–voltage relationships obtained in 10 A-673 cells before and after application of κ-Cono.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11216402

Here we use ATAC-seq and RNA-seq data from a compendium of GC cell lines and primary tumors to detect drivers of regulatory state changes and their transcriptional responses.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11774112

The tissues of the tumor, heart, liver, spleen, lung, and kidney were collected and stored in 4% paraformaldehyde overnight, which were then stained with hematoxylin and eosin (H&E).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9473868

The imbalance of FLS proliferation and apoptosis has been considered as an initiation factor in RA development .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "imbalance", "of", "FLS", "proliferation", ...

PMC11587541

Understanding how telomeres are affected in SMA can provide valuable insights into the disease process and may lead to the development of targeted therapies aimed at preserving telomere length and improving outcomes for SMA patients.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9429973

Then the MENK was added to kill the tumor formed within the femur.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Then", "the", "MENK", "was", "added", "to", "kill", "the", "tumor", ...

PMC11742047

Heatmaps depicting glycerophospholipids changes associated with CBD treatment observed in LC–MS (+).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Heatmaps", "depicting", "glycerophospholipids", "changes", "...

PMC11705547

Preclinical studies have shown that cisplatin promotes exosome secretion by the CAFs, which can inhibit ferroptosis in gastric cancer cells by reducing the accumulation of lipid-ROS, resulting in increased resistance to cisplatin .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8956657

no significance; ****p < 0.0001.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "no", "significance", ";", "*", "*", "*", "*", "p", "<", "0.0001", "." ] } ]

PMC11513011

DIB significantly suppressed wound healing in KK-47, T24, and 5637 cells.

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PMC9429973

Aims: We aimed to characterize the cellular composition and transcriptional alterations occurring in peripheral blood (PB) obtained from MF pts enrolled in the MANIFEST trial.

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PMC10440586

We validate the prognosis value of CD99 in glioma in multiple datasets.

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PMC9444294

ChIP was performed using 10 µg of chromatin and 2 µg of antibody (Active Motif, #53009, Carlsbad, CA, USA).

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PMC11188874

After drug treatment, E.G7-Ova cells were incubated with B3Z cells at an E:T ratio of 2:1.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "drug", "treatment", ",",...

PMC9430052

All pts presented with Ann Arbor stage IV disease.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "pts", "presented", "with", "Ann", "Arbor", "stage", "IV", "disease", "." ] } ]

PMC6379402

Then, the probability of connecting two nodes is equal to the product of their stickiness indexes.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Then", ",", "the", "probability", "of", "co...

PMC11657695

3KCNA2 expression is regulated by the chimeric protein EWS::FLI1.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "3KCNA2", "expression", "is", "regulated", "by", "the", "chimeric", "protein", "EWS::FLI1", "." ] } ]

PMC8557138

Nagy et al. reported the presence of six morphologically and functionally distinct tumor vessel subtypes including mother vessels, capillaries, glomeruloid microvascular proliferations, vascular malformations, feeder arteries, and draining veins; of which two of the vessel forms were capable of surviving in the absence...

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC6160470

We have previously developed a computational model, which enabled us to synthesise novel 18-crown-6 ether compounds.

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PMC7887261

Study participants were genotyped on an Axiom Exome Plus Array (Affymetrix), which contains a custom panel of key LC GWAS markers, and rare coding SNVs and indels.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11322866

The solid lines indicate direct interactions, while the dashed lines indicate potential interactions.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "solid", "lines", "indicate", "direct", "interactions", ",", ...

PMC9429973

Methods: We analyzed internal trial matrix database and examined other documents such as laboratory specification documents, trial design, protocol, and schedule of activities.

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PMC9429973

Patients were required to have at least one record of receiving both a cBTKi and a BCL2i.

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PMC8903741

The antigen-binding efficiency of each antibody differed because the characteristics of each antibody from mammalian cell expressions, such as post-translational modification including glycosylation, folding, and assembly might vary.

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PMC8662250

Immunoblot analysis revealed that CBD was able to reduce all the analyzed proinflammatory markers triggered by SP incubation, such as tool‐like receptor 4 (TLR‐4), ACE‐2, family members of Ras homologues A‐GTPase (RhoA‐GTPase), inflammasome complex (NLRP3), and Caspase‐1.

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PMC11496728

Normal cells without a transfection plasmid died.

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PMC11621493

B–D) Gene set enrichment plots of GO molecular function gene sets “Cytokine activity” and “chemokine activity,” as well as the GO biological process gene set “lipid catabolic process” comparing KO and WT cells in the absence of IL17A and TNFα (basal).

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PMC11683130

There is evidence that RNA silencing of SerpinB2 in keratinocytes leads to upregulation of IL-8, CXCL5 and CCL5 and increased neutrophil migration (117).

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PMC11055323

After 10 days, cells were fixed in 4% paraformaldehyde (Sangon, E672002-0500) for 20 min at room temperature and then stained with crystal violet (Beyotime, C0121-100 ml) for 10 min at room temperature.

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PMC9436459

Therefore, the use of bromine substituted substrates in these reactions would give a better combined yield of diene S46.

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PMC11518702

In chamber migration assays (using fibronectin), endogenous and ectopic expression of HGAL in IgM-stimulated *U2932 or Bjab cells (respectively) significantly attenuated SDF1-induced cell migration (55).

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PMC10808409

Bar chart showing percentage of cell population in each phase of the cell cycle analysis. *

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PMC11750165

The gain-of-function study using Tg[hsp70-Mib:EGFP] showed that the majority of cells in the p3 domain differentiated into KA” neurons after heat-shock during late neurogenesis (Ryu et al., 2015).

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PMC11046454

AptPTK7-induced specific contact between CAR-T and PTK7 K562 was first confirmed with flow cytometry (Figure 2G).

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PMC11507371

Studies have shown that ROS-inducing therapies are an effective anti-cancer strategy by increasing ROS levels.

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PMC9848491

The infiltration scores of 16 immune cells and the activities of 13 immune-related functions were calculated by single-sample gene set enrichment analysis (ssGSEA) using the “GSVA” package.

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PMC11307990

In this study, we fabricated precisely structured DNA nanotapes with strong surface SUN adhesion, enabling RTK inhibition of renal clear carcinoma cells.

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PMC11583690

Fig. 6A shows that free DTX, nanoparticles, and DTX-loaded nanoparticles have mild toxicity on Hs68 cells, with the percentage of viable cells decreasing gradually with increasing concentrations, although not significantly.

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PMC11742431

For example, Hu et al. inhibited Survivin expression at the transcriptional and protein levels to suppress tumor growth in tumor‐bearing mice.

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PMC11502443

Comparison of each peptide’s ability to induce signaling for different pathways at the WT GIP receptor. (

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PMC11680562

Additionally, immediate skin sensation was carefully evaluated, encompassing stiffness, grittiness, and greasiness .

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PMC9429973

Aims: This presentation provides an overview of EFG as a molecule and summarize the clinical development program to date.

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PMC11696576

An alternative route for the construction of the thiazolyl ring was also explored, in case of lack of commercially available TBDMSCN.

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PMC10482220

In cells subjected to arsenite stress, the CD mutant was recruited to SGs (in 86% of transfected cells).

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PMC8633974

Statistical differences between unstimulated compared to stimulated RT activity values and stimulated control compared to stimulated treatment RT activity values were calculated with two-way ANOVA followed by Sidak's post-hoc test for multiple comparisons.

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PMC11673902

The constriction channels can simulate the environment of capillaries in the body.

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PMC11703992

IL-6 expression has downregulations in the DDIT4-OE group and TNF-α expression has upregulations in the DDIT4-KD group.

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PMC9429973

For pathway inhibition specific compounds as well as shRNA-mediated knockdown were used for functional read-out of ADCP and viability in lymphoma co-culture.

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PMC11488203

Lipofectamine RNAiMAX reagent was obtained from Gibco/Life Technologies GmbH, Darmstadt, Germany.

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PMC11323699

Fig. 4).

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PMC11738017

Meanwhile, the emergence of antigen escape clones represents a recurrent mechanism of secondary resistance to anti-BCMA chimeric antigen receptor T-cell (CAR T) or TCE therapy.10, 11, 12, 13 BCMA antigen escape occurs through biallelic deletions of TNFRSF17 or monoallelic deletion, coupled with BCMA extracellular domai...

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PMC3813807

This showed that, in grades I, II and III gastric adenocarcinoma tissues, the upregulation of miR-373 was more marked than that in 15 matched normal tissues, while the mRNA levels of TNFAIP1 in all investigated gastric adenocarcinoma tissues were lower than those in matched normal tissues (Fig. 3A).

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PMC9429973

Aims: In this study, we investigated the role of EASIX and mEASIX scores in the prediction of transplant related complications and survival in patients undergoing allogeneic hematopoietic stem cell transplantation (alloHCT).

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PMC9429973

AMH is considered to be the most sensitive biomarker for gonadal reserve (decreasing values correlate with ovarian insufficiency).

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PMC9398137

A subset of DLBCL and majority of Burkitt lymphoma cell lines were sensitive to S63845.

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PMC10203589

In the diagnosis of pheochromocytoma (PCC) and paraganglioma (PGL) (172–174).

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PMC11682224

Under hypoxic conditions, CHD1L promoted the proliferation, migration, invasion, and angiogenesis of cutaneous squamous cell carcinoma.

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PMC11218145

Y-axis shows, relative to the controls, the absorbance at 595 nm obtained with the MTT assay as a proxy of the cell viability, and expressed as relative absorbance “RA”.

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PMC11470999

Moreover, knockdown of CIP2A markedly decreased melanoma cells' sensitivity to PF (Figure 4E,F).

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PMC11721295

We defined ligand-receptor pairs based on a curated, literature-supported list described by Ramilowski et al. (36) and further curated by Steele et al. (37).

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PMC11615743

Our work presents a proof of principle for the isolation of target cells using an L‐DNA‐based logic gate under optimal conditions for cell growth to minimize damage to cells caused by previous methods, which are typically conducted in an FBS‐free buffer.

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PMC11095939

It has been well documented that both overexpression and depletion of Mecp2 have deleterious effects on neuronal homeostasis (Na et al., 2013), and thus, tight regulation of Mecp2 protein levels is critical for its physiological functions.

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PMC11637716

This is further complicated by the fact that at the somatic level, there may be spontaneous genetic alterations which modify the expected phenotype, as recently exemplified by a loss of heterozygosity in favour of the ‘milder’ of the two variants in a subset of blood cells from a patient with EFL1‐associated SDS.

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PMC11763126

G H&E staining assessing metastasis levels in lung tissues.

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PMC11756937

Afterwards, the vial containing the cells was dried, dowsed with 70% ethanol and wiped dry again prior to placing it into the hood.

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PMC11321678

Subgroup‐specific TFs are identified and visualized on UMAP (Figure 3B).

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PMC10976516

Thus, tumor vasculature is an appealing element of tumor biology to target OV infection.

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PMC11286266

Normalised cell lysates (15–30 μg) were loaded as an ‘input’ control.

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PMC11765988

Sarcoidosis is characterized by non-caseating granulomas composed of epithelioid cells, whereas lymphomatous nodes primarily consist of lymphocytes and Reed-Sternberg cells.

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PMC11258145

Utilizing the Behrens method, the median lethal dose (LD50) was determined from the data presented.

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PMC11628309

A clear example is the use of 6-OHDA, a dopaminergic analog that is taken up into the cell through DAT (Hernandez-Baltazar et al., 2017).

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PMC11566417

Specifically, work in the bovine model has shown that the secretome of adult mammary stem/progenitor cells confers antimicrobial, regenerative, and immunomodulatory properties in vitro .

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PMC9429973

One way ANOVA test was used to compare continuous variables.

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PMC9985266

Increasing evidence shows that long noncoding RNAs (lncRNAs) have an important influence on PF .

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PMC10926885

We obtained the GSEA database and ran KEGG and GO enrichment analyses of NDE1 to learn more about the role that NDE1 plays in the immune regulation of cancer.

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PMC8956657

Each exhibit highly similar binding mechanisms that, in both cases, lack a prototypical Lys bound at their P2 site.

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PMC9429973

Summary/Conclusion: PET/CT is a valuable tool for response assessment in PMBCL after R-da-EPOCH, facilitating clinical decision making regarding further consolidative RT, which can be minimized.

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PMC8839885

2HE2 is considered a prodrug of 2ME2 since the conversion of 2HE2 to 2ME2 is very efficient .

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PMC11791203

Fig. 8(A) Three dimensional docking interaction images of 1,2-benzenedicarboxylic acid, Cyclododecanol, 2,4-Ditert-Butylphenol and Sulfurous acid, hexyl octyl ester onto Cox-2. (

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PMC11216402

We used RNA-seq data from the 25 GC cell lines to understand how the differential TF activity inferred from the ATAC-seq data affects gene expression.

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PMC10565698

H–K. Transwell migration (H and I) and invasion (J and K) assays with HCCLM3 and BEL-7407 cells following miR-211-5p mimic transfection. *:

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PMC9080589

We observed that the activation of Wnt signaling by LiCl treatment impaired the inhibitory effects of PCDH8 on the proliferation (Fig. 5C), metastasis (Fig. 5D) and apoptosis (Fig. 5E) of TPC-1 cells.

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PMC11629143

Flow cytometry analysis for eGFP reporter assays used an LX375 CytoFLEX flow cytometer (Beckman Coulter).

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PMC10728200

Among the 418 included patients, 397 patients (95.0%) were followed up completely and 21 were lost to follow-up.

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PMC10998613

This suggests that there was no significant heterodimerization between the receptors in this cell line.

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PMC10988808

As a receptor for NETs, it may be associated with liver metastasis of tumors [16–18].

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PMC11599565

Interestingly, the inhibition of MAP4K4 and Notch pathways induces the upregulation of both βIII-tubulin and ChgA, two classical neuronal markers.

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PMC10291556

The reaction products were analyzed by HPLC.

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PMC11349530

The reason for this may be that above-mentioned therapies usually target only one factor, whereas many factors are involved in tumorigenesis and cancer-related inflammation (110).

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PMC10507284

After eliminating patients without survival information, a total of 263 STS patients were enrolled for further analysis.

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PMC11704834

As demonstrated in Fig. 4Cb, acute ablation of TLE1 expression in A549GR cells partially restored their sensitivity to gefitinib-induced apoptosis.

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PMC11680391

However, the perspectives of the dairy farmer and the dairy veterinarian still differ because their starting point for conversation differs.

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PMC9429973

HCRU and costs (adjusted to 2019 US dollars) associated with induction and post-remission therapy were assessed during a treatment cycle.

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PMC11682172

We only found coronin-1A to be upregulated following T lymphocyte contact while the expression of its family members coronin-1B, coronin 1C and coronin 7 remained unaffected.

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