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Adverse reaction to metal debris (armd) in arthroplasty surgery of the hip is a well - known problem and has resulted in several products being withdrawn from the marketplace . Complications related to the release of metal ions can be devastating for patients and represent a significant surgical challenge . Although th... |
Type 2 diabetes (t2 dm) is a global public health problem and the number of affected individuals is increasing at an alarming rate [1, 2]. The pathogenesis of t2 dm is characterized by a progressive insulin resistance with eventual insulin deficiency . Both environmental and genetic factors are known to contribute to t... |
Neonatal diabetes mellitus (ndm) is a form of diabetes that is diagnosed under the age of 6 months . The most common causes of neonatal diabetes are activating mutations in the adenosine triphosphate (atp)-sensitive potassium (katp) channel . This review discusses functional effects and therapy implications of ndm muta... |
Mixed methods research uses both quantitative and qualitative data to improve understanding of a research problem beyond what is possible with either approach alone . Mixed methods studies are challenging for health researchers to plan and implement due to their design complexity and difficulties related to appropriate... |
Cross - sectional studies of community - residing samples revealed that 19%50% of elderly who developed dementia experienced disruptions in their sleep.13 moreover, sleep disruption appears to worsen as the disease progresses;4 it has been estimated that elderly in the later stages of dementia spend as much as 40% of t... |
Ventriculostomy catheters, also known as external ventricular drains (evds), are frequently used in neurosurgery to monitor and relief intracranial pressure . Complications arising from evds include hemorrhage, misplacement, dislodgement, blockage, and, most significantly, infection, which may be complicated by ventric... |
Malignant peripheral nerve sheath tumors (mpnsts) are very rare high - grade sarcomas with a poor prognosis at childhood and adolescence, and only 10%20% of mpnsts are seen in these periods.14 mpnsts often present with pain associated with mass lesions or neuronal involvement in the head neck, abdomen, chest wall, and ... |
It was a pleasure to read the report from dunham and coworkers concerning the relationship between hypocholesterolemia and outcome in patients following severe trauma . Although their study involved only 28 patients, these patients were severely injured (injury severity score 31 9) and they required at least 7 days of ... |
Cryptosporidium, a spore - forming protozoon, has been recognized as a human pathogen since 1976 . The species most frequently involved in human infections are cryptosporidium hominis, which primarily infects humans, and cryptosporidium parvum, which infects humans and animals such as cattle, although infection with un... |
In recent years, sedentary living and physical activity have become an important topic of research . Sedentary lifestyle presents a significant risk factor for human health (13). On the other hand, it was proven that habitual physical activity or exercise causes not only a reduction of the incidence of obesity, cardiov... |
Lung parenchymal calcifications are uncommon, but may occur in numerous conditions so their main differential diagnosis should be known by the radiologist . We demonstrate a rare etiology for lung calcifications in a 87 year - old male that came to our emergency department complaining of dyspnea and was diagnosed with ... |
It is well known that in type 1 diabetes mellitus, optimal glycemic control is extremely important to prevent or postpone long - term complications . In general, glycemic control in children with type 1 diabetes is monitored by measuring glycated hemoglobin (hba1c) and self - monitoring of blood glucose (smbg). As demo... |
Enzymes, of which structures and functions are prescribed in genes, basically mediate all metabolisms needed for the development and functions of living organisms . Among the many enzymes, protein tyrosine kinases (ptks) are known to play key roles in intracellular signaling for the development and functions of cells .... |
Metastatic or loco - regionally advanced non - small cell lung carcinoma (nsclc) is one of the leading causes of death attacked with cancer in india and though treatment outcomes in advanced disease remain modest, with the paradigm shift in the approach to treatments customized treatment based on the tumor histology an... |
One concept that unites all therapeutic modalities including the surgical, medical, pharmacological, physiotherapeutic (as well as other health professions - related) and the psychological, is change; specifically the valid confirmation of an improvement in a patient s health status due to intervention . This issue has... |
Functional popliteal artery entrapment syndrome (paes) is an important and possibly underrecognized cause of exertional leg pain . It shares many features with other causes of exertional leg pain, and more than one condition can be present at once, confusing the clinical picture . An understanding of the typical presen... |
The cardiovascular health study (chs) is a national institutes of health national heart, lung, and blood institute funded, population - based longitudinal study of adults aged 65 years (7). (a full list of principal chs investigators and institutions can be found at http://www.chs-nhlbi.org/pi.htm .) The main objective... |
The use of nickel - titanium (niti) rotary instruments for root canal system preparation has increased due to their undeniably favorable qualities; however, unexpected fracture is an important disadvantage of these instruments [13]. Controversy remains regarding the contribution of torsional fracture, fatigue fracture ... |
Congenital hereditary endothelial dystrophy (ched) is a corneal dystrophy characterized by bilateral diffuse clouding of the corneas, causing impaired vision . Depending on the mode of inheritance, it manifests either in infancy or young childhood with a cloudy cornea, light sensitivity, tearing, and sometimes nystagmu... |
Adrenohepatic fusion is a relatively common condition that has been reported in the literature and explained as a result of normal aging . However, the presence of a neoplastic process in the adrenohepatic fusion is relatively uncommon, especially when it is a malignant neoplasm . Here, we present a patient with a mali... |
D - amino acid oxidase (ec 1.4.3.3, daao) is a flavoprotein that catalyzes the enantioselective oxidative deamination of d - amino acids to yield the corresponding -imino acids, which are spontaneously hydrolyzed to -oxoacids and ammonia . Reoxidation of the reduced fad by molecular oxygen is accompanied by the release... |
The long - appreciated beneficial properties of the trifluoromethyl group in medicinal chemistry and the imperatives of green chemistry provide the impetus for the current resurgence of interest in the development of trifluoromethylation methods . The ability to produce ever more complex trifluoromethylated substances ... |
Moringa oleifera lam . Found in most parts of ghana belongs to the monogenetic family moringaceae (order brassicales). Its nonmedical uses include use of the seeds in wastewater treatment due to their coagulant properties [1, 2]. Its medicinal uses stem from the fact that the entire plant has high protein, vitamins, mi... |
Chronic hepatitis b (chb) virus (hbv) infection is the principal cause of cirrhosis and hepatocellular carcinoma (hcc). The pathogenesis of hbv - related chronic liver disease is not well understood . However, it is clear that the immune mechanisms associated with the antiviral response are responsible for chb outcome ... |
Its raw or processed roots are the only organ source for clinical uses of traditional chinese medicine, and the leaves are not utilized at all . However, r. glutinosa leaves have the pharmacological effects and can nourish yin, tonify qi and kidney, and promote blood circulation . In the folk, the fresh leaves are ofte... |
Leiomyoma, a benign smooth muscle neoplasm is classified by world health organization on the basis of histopathology into three types: 1) solid, 2) vascular (angiomyoma, angioleiomyoma) and 3) epithelioid . Leiomyoma is a common neoplasm of uterus and gastrointestinal tract mostly occurring in solid variant . In the he... |
A 36-year - old woman presented at our institution (gachon university gil hospital) with erythematous confluent maculopatches on her face, trunk, and palms; jaundice; fatigue; pruritus; and aggravation of skin lesions over the previous week . She had been previously diagnosed as having erythema multiforme 2 weeks earli... |
We report a case of a female patient on aspirin and warfarin who developed a retropharyngeal haematoma following minor blunt head and neck trauma . An 84 year old woman had a mechanical fall at ground level resulting in neck hyperextension . A rigid cervical collar was applied and anterior neck and chest swelling and b... |
This type of infection is related, among others, to the type of the transplanted organ . Invasive candidiasis occurs more often in liver recipients, and invasive aspergillosis in lung recipients [13]. Invasive candidiasis is one of the main post transplant complications, presenting a high risk of death . There are thre... |
Asthma is a disease that is caused by inflammation in the lung and bronchus and is affected by genetic and environmental influences . Aspirin - exacerbated respiratory disease (aerd), which was first reported in 1922, is a type of asthma . Aerd is characterized by the following three symptoms: bronchial asthma, aspirin... |
The dengue virus strains sequenced for this study as well as sequences obtained from genbank for this study are listed in table 1 . The virus isolates were obtained from the centers for disease control and prevention, dengue branch, puerto rico, and division of vector - borne infectious diseases, ft . Collins, colorado... |
Adult attention deficit hyperactivity disorder (adhd) is an extremely debilitating neurodevelopmental disorder that often persists beyond childhood, affecting 2.5%5% of adults in the general population.1 it is one of the most frequent psychiatric disorders that affect the childhood population, and recent data suggest t... |
With estimated 80,000 deaths among children in 2013, tuberculosis (tb) continues to be major infectious disease among children . Low- and middle - income countries bear disproportionate burden with more than 50% of the global cases occurring in southeast asia and the western pacific . India alone accounts for 27% of th... |
Monocytes and macrophages, which are categorized among the leukocytes, play a pivotal role in the innate immune system [13]. Their origin lies in a common myeloid precursor, while they both play important roles in innate immunity . Macrophages, which are produced from monocytes after their exposure to certain stimuli, ... |
Emergence agitation (ea) was described at first by eckenhoff et al in the early 1960s . Ea has been described as a dissociated state of consciousness in which the child is inconsolable, irritable, uncooperative, typically thrashing, crying, moaning or incoherent . Nowadays, about 4 million children undergo general anes... |
The study included 79 obese patients undergoing weight - reducing surgery and 14 lean patients who underwent elective cholecystectomy . Participants were included if they had fasting blood glucose levels <7.0 mmol / l, no history of diabetes or use of glucose- or lipid - lowering drugs, and no weight changes> 3% during... |
Cardiac events are a leading cause of death worldwide and despite our best life support efforts outcomes after cardiac arrest are still poor . The european resuscitation council (erc) cardiopulmonary resuscitation (cpr) 2010 guidelines emphasize the importance of minimizing the interruption of chest compression to maxi... |
Intacs (addition technology inc, des plaines, il, usa) are intrastromal corneal rings consisting of two thin, clear hexagonal polymethyl methacrylate segments . They are placed in surgically created semicircular channels between the stromal lamella at two - thirds the stromal depth during an outpatient procedure . Intr... |
Apoptosis is a type of genetically regulated programmed cell death that controls the development of multicellular organisms and tissues by eliminating physiologically redundant, physical damaged, and abnormal cells . Studies focusing on the genes and signals regulating apoptosis have played an important role in basic o... |
The spect acquisition in lung perfusion scan provides higher sensitivity and specificity to detect pulmonary thromboemboli (pte) compared to planar imaging (1, 2). Because of higher specificity, there are hopes that the lung perfusion spect could be interpreted without a ventilation study . The value of higher specific... |
The primary complaint of most patients with this tumor is testicular swelling, which is usually painless . It is not uncommon for this tumor to be of an advanced stage at the time of the diagnosis, and the prognosis is dismal . Although scrotal swelling is the most common manifestation, the clinical presentation is oft... |
Functional fitness not only accounts for the traditional physical fitness parameters such as muscle strength, cardiorespiratory endurance, and flexibility, but also includes balance . However, it is well known that, with age, functional fitness declines, resulting in a reduced ability to perform activities such as risi... |
Participants were chinese women with a hong kong permanent identity card who were: aged 1865 years;able to read chinese or english;not pregnant . Able to read chinese or english; the study was approved by the institutional review board of the university of hong kong . A total of 379 women were recruited in a private me... |
We report on the prevalence of different antimicrobial - drug resistance profiles among danish salmonella ser . Furthermore, we show results indicating that a dt104 outbreak strain lost resistance genes by shifting to the sgi1-b variant during the outbreak . Consequently, the outbreak included isolates with both the ac... |
The connection may occur as a result of iatrogenic causes during root canal treatment (at the level of the floor of the cameral cavity or at different levels of the root) or during prosthetic treatment for postcanal penetration . Prognoses for perforated roots depend on the time lapsed before the perforation is sealed,... |
Advantages of using prefabricated adhesive posts include improved aesthetics and retrievability, as well as the need for only one treatment / visit . Due to the lower elastic modulus of fiber posts which are closer to that of dentin, better stress distribution is expected . Clinical studies; however, show that failure ... |
Diseases that belong to spondyloarthritides (spa) are frequently manifested as asymmetric peripheral arthritis of the large joints with knee involvement . Tumour necrosis factor (tnf) inhibitors are highly effective for the treatment of peripheral arthritis in patients with ankylosing spondylitis (as) [1, 2], psoriatic... |
Type 1 diabetes is an autoimmune disease resulting from destruction of pancreatic - cells by infiltrating immune cells . The nod mouse is an important model of spontaneous autoimmune diabetes that has been used to understand type 1 diabetes pathogenesis and develop therapeutics to prevent - cell destruction . Similar t... |
Lagophthalmos is defined as the inability to close the eyelids completely.1,2 orbicularis oculi muscle that closes eyelids is innervated by facial nerve (cnvii). Paresis of the orbicularis oculi muscle leads to diminished blink, lagophthalmos, and impairment of the nasolacrimal pumping system . Lagophthalmos may be the... |
Superior mesenteric artery syndrome (smas) is a rare condition causing acute or chronic compression of the third part of the duodenum, due to a reduction in the aortomesenteric angle . Laparoscopic duodenojejunostomy is a minimally invasive option that has been reported in up to 10 cases . We describe our operative tec... |
Bipolar disorder (bd) is a clinically severe psychiatric disorder, characterized by recurrent alternating episodes of mania and depression, with a lifetime prevalence of 0.7%6% [13]. Given its high morbidity, disability, and premature mortality, bd is a major health problem with severe socioeconomic implications . The ... |
The inhibition of 1 on cell - free melan - a tyrosinase was demonstrated by a lineweaver burk plot . The results shown in figure 1 revealed both 1 and resveratrol to be noncompetitive inhibitors of tyrosinase, with kojic acid being a competitive inhibitor . Thus, the addition of 1 to the reaction mixture led to a reduc... |
In africa, the health impact of schistosomiasis, whether caused by schistosoma haematobium or by s. mansoni, is a well - known public health problem, one that is now receiving well - deserved attention . This attention is focused primarily on the most vulnerable part of the community, that part of the population that i... |
The online version of this article (doi:10.1007/s11032 - 015 - 0192-x) contains supplementary material, which is available to authorized users . Supplemental table 1 primer pairs used in this study (xls 32 kb) supplemental fig . 1 graphical genotype of a bc2f5 line (hk114) used for substitution mapping of rbg2 . Positi... |
Vigabatrin (vgb) is an antiepileptic drug that irreversibly inhibits brain -aminobutyric acid (gaba) transaminase (1). Vgb is used as first - line treatment for infantile spasms, especially those secondary to tuberous sclerosis, and as an adjunct therapy for medically resistant localization - related childhood epilepsi... |
Paraneoplastic pemphigus (pnp) is an extremely severe autoimmune blistering disease associated with neoplasms; the disease is most commonly of lymphoproliferative origin and presents a high mortality 1 . Follicular dendritic cell (fdc) sarcoma is rare and classified either as a conventionaltype or as an inflammatory ps... |
The 2-year survival of patients starting rrt has progressively increased for cohorts from 2001 to 2006, measured either as overall survival for patients starting rrt (to 82.2% for the cohort starting in 2006 reported in the era - edta registry 2012 report), on dialysis (79.7%) or receiving living - related kidney trans... |
Since serum prostate specific antigen (psa) was introduced as an early detection marker of prostate cancer (pca) in the 1980s, several trials involving novel and more precise biomarkers have failed to provide new markers with definitive clinical relevance and applicability . Considering the low sensitivity of psa and t... |
Homozygous loss - of - function mutations in the gba1 gene cause gaucher disease (gd), the commonest lysosomal storage disorder . This gene encodes glucocerebrosidase (gcase), a lysosomal enzyme responsible for the hydrolysis of the glycolipid substrate glucosylceramide (glccer) to ceramide and glucose . Reductions in ... |
Data were derived from the third national health and nutrition examination survey (nhanes iii, 19881994), a representative survey of the civilian, noninstitutionalized us population conducted by the national center for health statistics (nchs) of the center for disease control and prevention . Details of the survey des... |
Syndrome research reveals detailed insight into different aspects of congenital malformation of several body components . Such a wide - spread field of interest requires multidisciplinary teamwork, including clinicians and researchers with different backgrounds . In the last decade a complete overview of craniofacial s... |
Unilateral ventriculomegaly is well - described in children secondary to neoplastic or infectious causes, and also due to congenital atresia, with or without the presence of a membrane . Idiopathic occlusion of the foramen of monro in adulthood is exceedingly rare, with only 14 cases previously described . These patien... |
Although even the complete absence of attached gingiva is compatible with oral health, certain clinical situations require definitive gingival augmentation . An epithelized autogenous masticatory mucosal graft procured from palate is preferred by most of the clinicians to increase the zone of keratinized tissue . Leadi... |
Cysteine - rich peptides are of significant and growing interest due to the increasing use of tetracysteine tags for fluorescence imaging of living cells(1) and as tools for bioremediation and phytoremediation of toxic heavy metal contaminants such as cadmium and mercury. (2) a library of 205 designed tetracysteine pep... |
Cell culture and reagents293 t cells were maintained in dulbecco's modified eagle's medium supplemented with 10% fetal bovine serum and transfected in 6- or 12-well plates by using the calcium phosphate method leading usually to> 70% transfection efficiency . 0.25 g of htt73 encoding plasmid were transfected together w... |
Cardioembolic stroke, which is an important subtype of ischemic stroke, involves a large infarct volume and multiple vascular territories . The neurologic deficits are grave and develop abruptly.1,2 because cardioembolic stroke is generally severe and frequently recurs, its long - term mortality is high.3,4 in addition... |
This occurs mostly through the action of dedicated transcription factors (tfs), as in the well - known case of the lac operon (jacob et al ., 1960). On the other hand, gene expression is continuously adjusted to adapt to varying environmental conditions, leading to quantitative relationships between the molecular conte... |
The face is widely regarded as a symbol of self and a smile as a window into one's personality . In this, the teeth play important roles in the maintenance of a positive self - image, and loss of teeth may result in significant disabilities that can profoundly disrupt social activities . Tooth loss may be traumatic and... |
Cronkhite - canada syndrome (ccs) was first described in 1955 by cronkhite and canada . The main symptoms of ccs are diarrhea, weight loss, abdominal pain, and other gastrointestinal complications, such as protein - losing enteropathy and malnutrition with diffuse polyposis in the digestive tract . Ccs is a rare non - ... |
We used data from the 2006 brazos valley community health assessment (bvha), which was developed by a collaboration of local and regional academic and community - based organizations in the brazos valley of central texas . Participants were recruited from adult community residents who resided in one of six rural and on... |
Thunderclap headache attributed to reversible cerebral vasoconstriction (tharcv) is a clinical - radiological entity observed in a number of cases reported since 1978 . The tharcv syndrome may include several of the patients experiencing thunderclap headache [28], headache associated with sexual activity [2, 812], isol... |
97% of the deaths related to childhood cancer occur in the developing world and with the poor resources and multiple other associated problems the survival rates of most childhood cancers do not approach the figures for the developed world . Nephroblastoma or wilms tumour is the most common renal tumour seen in childre... |
Chip - seq, gro - seq, or rna - seq libraries were also generated from imr90, huvec, mcf7 or lncap cells and sequenced on the illumina hi - seq2000 platform . More information about the experiments and detailed descriptions of hi - c data analysis pipeline, including data filtering, normalization, statistical modeling ... |
Thromboembolic complications have been described in hiv infected patients with higher incidence seen in patients with active opportunistic infections (oi) or malignancy, and in patients with acquired immunodeficiency syndrome (aids). Various abnormalities predisposing to hypercoagulable state have been reported in aids... |
Mitochondria are highly dynamic organelles that frequently fuse and divide in disease, aging, and development . In vertebrates, mitofusin-1 and -2 (mfn1 and mfn2) are involved in mitochondrial fusion, whereas drp1 and mitochondrial fission factor (mff) control mitochondrial fission . Recently, it was reported that the ... |
Medication overuse headache (moh) is a chronic headache disorder due to overuse of analgesic medicines, taken to treat a primary headache, and remitted by drug discontinuation . Moh has long been considered as a biobehavioural disorder, in which the biological predisposition to develop a chronic headache interacts with... |
Accurate functional assessment of lesion severity is crucial for clinical decision making in patients with intermediate coronary stenosis . Fractional flow reserve (ffr) is determined by the ratio of pressure distal to the lesion (pd)/pressure proximal to the lesion (pa) under maximal hyperemia . The pressure gradient ... |
Type 2 diabetes (t2d) is one of the leading causes of mortality worldwide, largely due to vascular complications including myocardial infarction and stroke [1, 2]. Endothelial function, a key determinant of vascular health, is impaired in the diabetic vasculature primarily due to reduced nitric oxide (no) bioavailabili... |
Ribonucleotide reductases (rnrs) catalyze the conversion of nucleotides to deoxynucleotides in all organisms providing the monomeric precursors required for dna replication and repair. (1) the escherichia coli class ia rnr is composed of two subunits: r1 (2) and r2 (2). Each subunit is homodimeric and a 1:1 complex of ... |
Systemic lupus erythematosus (sle) is a chronic autoimmune disease of unknown cause which can affect several parts of the body even central nervous system (cns).. among cns manifestations, cerebrovascular accident (cva) is one of the severe complications . Previous cohort studies revealed that 3 - 20% of sle patients m... |
Illumina hi - seq 2500 data is deposited at the ncbi gene expression omnibus (geo) database under geo series and is available at the following link: http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=gse64507 . S2 cells were maintained at 28 c in schneider's drosophila medium (invitrogen), supplemented with 10% heat - i... |
Collapse of the hard and soft - tissues occur following extraction and the severity of the horizontal and vertical loss of tissue may reach up to 60% after 2 years . Considerable volume of post extraction ridge loss is encountered in the 1 year of tooth loss . These localized ridge defects are characterized by regional... |
The majority of the developed countries try to associate economic growth with the provision of certain social services and, in this manner, aim at progressively improving the well - being of citizens . Accordingly, a social welfare model was developed to guarantee that everyone had, among other things, access to health... |
Platform switching, also known as diameter shifting, is a technique combining an implant with a reduced diameter abutment.12 the concept was introduced in the early 1990s after development of a wide diameter implant that was connected to the standard abutment.2345 since it was introduced, the technique has been evaluat... |
Mitochondria are essential organelles whose replication, development, and physiology depend upon coordinated interactions between gene combinations from both the mitochondrial and the nuclear genomes . When genes from both genomes interact, their differing modes of inheritance, bi - parental versus maternal, can result... |
The only naturally fluorescent amino acids are the aromatics, i.e., tryptophan, tyrosine, and phenylalanine, but in general tryptophan fluorescence dominates tyrosine fluorescence, and both dominate phenylalanine fluorescence . The endogenous fluorescence from tryptophan has been used to study properties of proteins si... |
The differential diagnoses of a groin mass include inguinal hernia, round ligament varicosities (rlv), mesothelial cysts, lymphadenopathy, endometriosis, subcutaneous lipoma, cyst of nuck (persistent embryonic remnants of the process vaginalis with cyst formation), vascular aneurysms, soft tissue malignancies, abscess,... |
Acute myocardial infarction (ami) results from total coronary artery occlusion, usually due to thrombus formation on complicated atherosclerotic plaque . The patients with ami have higher mortality rates, especially during the first 30 days . Platelets play an important role in development, destabilization, and rupture... |
Popliteal artery stenosis or occlusive disease is a common occurrence in elderly patients, diabetics, smokers and those with cardiovascular disease . It leads to significant morbidity and mortality by reducing or completely blocking blood supply through the popliteal artery and into the lower leg . We describe an unusu... |
Laparoscopic posterior mesh rectopexy (lpmr) is a good surgical option for rectal prolapse with low morbidity and mortality . Specific complication like mesh erosion into the rectum following lpmr is very rare with only one such case, in which mesh got expelled via rectum, reported in literature till date . We report a... |
Its phenotype is predominantly characterized by sensorimotor polyneuropathy and/or infiltrative cardiomyopathy (cm).1,2 moreover, ttr causes a nongenetic disease with deposition of wild - type (wt) ttr amyloid (attr) mainly in the heart of elderly males.2 in contrast to the hereditary form, no typical mutation in the t... |
Eligible patients were required to have histologically or cytologically proven inoperable stage iiia or iiib nsclc as defined in the tnm classification of malignant tumors (6th edition), no previous chemotherapy or radiation therapy, a performance status of 01 on the eastern cooperative oncology group scale, adequate b... |
Root canal preparation is performed with the use of endodontic instruments and auxiliary chemical substances, seeking to achieve cleaning, shaping, and disinfection, in order to fill the root canal later . The use of rotary nickel titanium (niti) instruments has increased considerably due to their safe use, when used i... |
Duchenne muscular dystrophy (dmd) is a recessive x - chromosome - linked disease that affects ~1/36006000 liveborn males . The muscular weakness is progressive, causing loss of ambulation by early adolescence (between 9 and 12 years of age). Dmd is caused by mutations in the dmd gene that code for dystrophin, a sarcole... |
Scleroderma, or systemic sclerosis, is a chronic connective tissue disease generally classified as one of the autoimmune rheumatic diseases a 58-year - old woman was informed of her scleroderma, while receiving oral prosthetic rehabilitation . The psychological load of the disease itself, along with dental treatment ce... |
Bloodstream infection is a leading cause of morbidity and mortality in neonatal intensive care units . The microbiological diagnosis of sepsis in newborns (nbs) is a difficult task, because blood culture (bc), which is currently the gold standard for diagnosing nbs (1) has the disadvantage of producing an elevated perc... |
Adenoid cystic carcinoma (acc) is a malignant tumor characterized by perineural invasion, slow growth, and insidious destruction of surrounding tissues . It usually arises in the major salivary gland, but also in minor salivary gland occasionally . Acc arising in the pterygopalatine fossa is extremely rare, only 3 case... |
Lead poisoning has been recognized as a major public health risk, particularly in developing countries . The release of lead into the environment from automobile emissions, lead - based paint or kitchenware, incineration of waste containing lead additives, and the burning of coal and its subsequent bioaccumulation has ... |
Papillary thyroid carcinoma (ptc) is the most common form of thyroid gland carcinoma which accounts for 1% of all human malignant tumors . It was reported that the prognosis of ptc is excellent with a 10-year survival exceeding 90% . However, approximately 2050% of ptc patients were found to have central lymph node met... |
Fasting during ramadan, the 9th month in the islamic calendar, is not mandatory for patients with diabetes mellitus (dm), but many insist on fasting . Glucose - lowering therapies are cornerstone for treating all type 2 dm patients to ensure tight glycemic control to prevent acute complications like hyperosmolar nonket... |
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