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All bacterial isolates related to the outbreaks (1 per patient) were obtained from clinical samples . The strains were identified phenotypically by rapid i d 32 strep (biomrieux, marcy letoile, france), which yielded profile 22025001100 (leuconostoc spp . (biolog, hayward, ca, usa) (98%, t = 0.708). The results were co... |
The immunosuppressive receptor pd-1 and its ligand pd - l1 have been identified by dr . Tasuku honjo and his colleagues at the kyoto university as factors that induce programmed cell death . Since the mechanism mediated by pd-1 and its ligand was shown to be important for immune suppression and tolerance, it has also b... |
Placenta accreta is a pathology characterized by abnormal and firm attachment of the placenta to the myometrium.1 the depth of penetration of the placental villi into the myometrium defines three severity levels of placenta accreta; accreta, increta, and percreta . Accreta, the least severe and most common of the three... |
The annual frequency of drug shortages increased 200% from 2006 to 2010 . Furthermore, in 2012 the food and drug administration (fda) reported a record number of 251 drugs on shortage . The increasing problem of drug shortages has the potential to adversely affect patient care, delay medical procedures, result in medic... |
Atrial fibrillation (af) is the most common sustained arrhythmia encountered in clinical settings . It is associated with higher risk of mortality, accounting for approximately 12% of all deaths in the general population . The prevalence of af increases substantially with age, affecting around 10% of people over 80 yea... |
Oro - facial - digital syndromes (ofds) are a rare heterogeneous group of development disorders in which at least nine different forms have been described . Ofd ii mohr's syndrome is transmitted as an autosomal recessive condition characterized by malformations of the oral cavity, face and digits . Facial and oral feat... |
During the last decades, evidence has emerged to support the relationship between periodontal infection and systemic conditions including cardiovascular diseases, diabetes, obesity and metabolic syndrome . Unlike the most common form of chronic periodontitis (cp), aggressive periodontitis (agp) develops early in life, ... |
Breast cancer is the most common type of cancer in canadian women [1, 2]. Every year in ontario, radiation therapy has been established as an effective adjuvant therapy for breast cancer . With radiation therapy, patients no longer need to undergo mastectomy to remove the whole breast . Instead, only a small part of th... |
The histologic confirmation is necessary for the definite diagnosis and is essential in determining the treatment for patients with cardiac tumors . Depending on the various clinical situations, tissue diagnosis can be made with less invasive methods including cytologic evaluation of pericardial or pleural fluids, or p... |
The lancefield group g beta - hemolytic streptococci (ggs) have been recognized as pathogens causing serious infections in humans, although ggs can have a commensal relationship when present on the skin, pharynx, intestinal tract, and vagina.1 the major pathological conditions predisposing ggs infections include malign... |
Polycystic ovary syndrome (pcos) is the most common endocrine disorder in women of reproductive age . Pcos produces symptoms in approximately 5 to 10% of women of reproductive age (1245 years old) and is thought to be one of the leading causes of the female subfertility . Pcos is a medical condition, in which there is ... |
The mucoadhesive polymer containing oral drug delivery systems has the capacity to prolong residence time of drugs at the absorption site and facilitate intimate contact with underlying absorptive surface to enhance bioavailability . Polymers used in the mucoadhesive formulations include natural, semisynthetic, and syn... |
Heart failure (hf) can result from cardiac overload or injury as well as from a complex interplay of genetic, neurohormonal, and inflammatory factors . Hf is classified as being associated with a reduced ejection fraction (hfref) or with a normal ejection fraction (hfnef). The percentages of patients and the mortality ... |
Muscle morphological characteristics, such as anatomical muscle cross - sectional area (csa), muscle length, and muscle volume (mv) are important physiological variables for assessing the functional capacity of a muscle . Although magnetic resonance imaging (mri) and computed tomography scans are the gold standard for ... |
Cardiomyogenesis (generation of cardiomyocytes) had not been convincingly demonstrated in the adult mammalian heart until very recently; the potential for myocardial regeneration was only recognized in organisms such as fish and amphibians . However, carefully designed and performed studies have produced compelling evi... |
Data were obtained from the finnish national prescription register and special reimbursement register, maintained by the social insurance institution (sii) of finland . The national prescription register contains records of all reimbursed drug purchases of all finnish residents living in noninstitutionalized settings .... |
The interventions for carotid artery stenosis, vein graft and acute myocardial infarction could embolize a large amount of plaque debris, especially unstable, ulcerative, and thrombus containing lesions (1). Distal protection devices such as filterwire ex have been widely used in carotid artery stenting to prevent dist... |
Although cutaneous melanoma represents less than 5% of the skin cancer is responsible for 80% of cancer deaths with this localization . Many studies have also shown that superficial spreading melanomas are found in histological contiguity with a dysplastic nevi . Tumor infiltrating lymphocytes are playing an important ... |
Fracture of stems in primary cemented hip arthroplasty is a known complication and has been attributed to varus positioning, excessive weight of the patient, resorbtion of the femoral calcar and failure of the cement mantle . Attribute this to reduction in proximal support either in the form of bone loss or an extended... |
These include open, laparoscopic, or endoscopic approaches . However, there are disadvantages and limitations with each of these techniques . The open method requires a large incision with its associated morbidity, and the laparoscopic techniques described so far are technically challenging in the pediatric population ... |
However, due to the high computational cost required for reconstruction, its real - time imaging applications remain challenging . Bolus - chasing computed tomography (ct) angiography is a primary example which demands real - time ct feedback . To address this problem, for example, xtrillion (by terarecon, inc .) Uses ... |
The amination of c h bonds provides a route to n - alkyl and n - aryl amine derivatives that avoids typical functional group interconversions and reactants containing a functional group already present at the position where a c n bond is desired . N bonds are particularly challenging to achieve, but such reactions coul... |
Sales and service workers face customers during working hours and the standardized expression of emotions, including kindness and sympathy, are important components of their job requirements (1). Standardized expression of emotions is socially desirable, especially to the organization, and it is essential to maintainin... |
The traditional medical practitioner or traditional healer can be defined as someone who is recognized by the community in which he lives as competent to provide health care by using vegetable, animal and mineral substances and certain other methods based on the social, cultural and religious backgrounds as well as the... |
To differentiate between the individual diagnoses of patients presenting at memory clinics with cognitive complaints and often depressive symptoms, more accurate diagnostic measures are needed . The term subjective cognitive impairment (sci) describes patients with subjective cognitive complaints and occurs before mild... |
Major problem in ocular therapeutics is the attainment of optimal drug concentration at the site of action, which is compromised mainly due to precorneal loss resulting in only a small fraction of the drug being ocularly absorbed . The effective dose administered may be altered by increasing the retention time of medic... |
Neurofibromatosis affects 1:3,000 individuals, and characterized by largely benign but often debilitating tumors that grow in the nervous system . Its course is unpredictable: it can cause a variety of benign nerve tumors including plexiform, dermal, and optic glioma tumors; in some cases malignant peripheral nerve she... |
Micropolar fluids are those fluids consisting of randomly oriented particles suspended in a viscous medium, which can undergo a rotation that can affect the hydrodynamics of the flow, making it a distinctly non - newtonian fluid . They constitute an important branch of non - newtonian fluid dynamics where microrotation... |
We report a case of sle - associated myopericarditis in a young male without clear evidence of viral infection based on viral markers in blood . The patient's cardiac function dramatically improved after treatment with steroids without any additional complications . A 19-year - old male was admitted to the combined arm... |
The rapidly increasing use of microwave radiation, has raised public concern about possible detrimental effects of non - ionizing radiation sources which work in this frequency range (13). Radio detection and ranging (radar) equipments send and transmit high - power rf waves by producing a high - voltage and high frequ... |
A 4-year - old male neutered domestic shorthair cat was presented to the oregon state university cardiology service for suspected pericardial effusion . Cardiac tamponade was documented and pericardiocentesis yielded purulent fluid with cytologic results supportive of bacterial pericarditis . The microbial population c... |
Germline mutations in the tumor suppressor genes brca1 and brca2 account for 3% to 5% of all breast cancer cases and 10% to 15% of ovarian cancer cases . The lifetime risk of breast cancer in brca1 and brca2 mutation carriers is estimated at 47% to 66% and 40% to 57%, respectively . The ovarian cancer risk in brca1 and... |
Data for the analysis were collected through structured phone interviews with a national sample of 27 hmos . The surveyed hmos include 15 hmos currently serving rural medicare risk enrollees, 1 hmo that recently dropped its medicare risk contract to serve rural enrollees, and 11 hmos that have commercial enrollees in 5... |
This randomized, double - blind, placebo - controlled, parallel group, 24-week study with a subsequent 24-week extension enrolled male and female patients with type 2 diabetes between 29 july 2008 and 4 july 2009 . The study took place at 105 sites in argentina, canada, india, mexico, peru, philippines, taiwan, and uni... |
Chronic kidney disease (ckd) is a public health problem that affects more than 20 million people in the us . An average dialysis patient may require more than 12 medications . A pooled analysis identified 1,593 medication - related problems in 385 dialysis patients, with over- or under- dosing errors accounting for 20.... |
In this article we will use the term variable number tandem repeat (vntr) to encompass both microsatellites and minisatellites however not all tandem repeat domains are polymorphic in repeat copy number . Sva elements only represent 0.13% of the genome, representing ~2700 elements, constituting the youngest of the retr... |
Bicycle riding is popular throughout the world for transportation, recreation, sports, and health - related benefits . 53% are men . In korea, according to the needs of the times, such as economic development and increased leisure time, a trend for preferring environmentally friendly sports, and growing interest in hea... |
However, it is difficult to determine an appropriate resection line using only the laparoscopic approach . For more appropriate resection, laparoscopic and endoscopic cooperative surgery (lecs) on the other hand, gastric plexiform angiomyxoid myofibroblastic tumor (pamt) has recently emerged as a new entity among gastr... |
Myelodysplastic syndromes (mdss) represent a group of clonal hematological disorders characterized by progressive cytopenia reflecting defects in erythroid, myeloid and megakaryocytic maturation . Anemia, neutropenia and thrombocytopenia, separated or in combination, despite a hyper- or normocellular marrow define mds ... |
Intracranial foreign bodies via the transorbital route are rare.1 amongst cases of transorbital intracranial injury, projection of the foreign body through the superior orbital fissure occurs in an estimated 68% and damage typically occurs to the brainstem, cavernous sinus, or temporal lobe.2 introduction of a foreign ... |
Because of the therapeutic potential of inhibiting fatty acid amide hydrolase (faah) for the treatment of pain, inflammatory, or sleep disorders, there is a continuing interest in the development of selective inhibitors of the enzyme . The distribution of faah is consistent with its role in regulating signaling fatty a... |
To introduce a case of iridoschisis patient who underwent cataract surgery successfully without pupil device . A 64-year - old female who showed iridoschisis of her both eyes underwent cataract operation at her right eye without a pupillary device . The preoperative and postoperative ophthalmologic examinations includi... |
Neural stimulation has a long history of use in a range of therapeutic applications, including regulating organ function and treating a variety of neurological disorders . Neurostimulators are also used to provide forms of sensory perception; for example, electrical stimulation of auditory neurons using electrodes impl... |
Urolithiasis in children remains endemic in our region afflicting children of <1 year to 15 years of age . In fact stone disease comprises more than 60% of the urological disease burden in a urology center . Many children present late with large stone burden associated with varying degree of renal failure . In develope... |
Patients undergoing orthopedic surgery are of different ages and sizes . Regional analgesia and anesthesia are often beneficial for these patients . The choices of anesthesia are as varied as the operations done through the scope, and include general blocks, central neuraxial blocks, peripheral nerve blocks, and intra ... |
Noncompaction cardiomyopathy (nccm) is a recently recognized rare disorder [1, 2]. It is characterized by prominent myocardial trabecularizations, and deep intertrabecular recesses leading to the spongy appearance of the myocardium . The disease is frequently associated with systolic and diastolic heart failure (hf), v... |
Peribiliary cysts are cystic dilatations of the peribiliary glands of the liver hilum and portal tracts, which lack communication with the lumen of the biliary tree [1, 2]. Peribiliary cysts are often under diagnosed, however, as they are usually asymptomatic and the reported prevalence based on imaging diagnosis is on... |
A 49-year old woman presented in october 2007 with abdominal bloating, pain, and obvious ascites . After imaging data was obtained, in december 2007 the patient underwent total abdominal hysterectomy (tah)/bilateral salpingo - oophorectomy (bso) and debulking surgery to remove as much of the tumour as possible . After ... |
Song et al.1 first reported the anterolateral thigh (alt) flap as a septocutaneous flap based on the descending branch of the lateral circumflex femoral artery (lcfa) in 1984 . Recently, the alt flap has become a popular option for soft tissue reconstruction of the oral cavity23 . It is easily raised and has long and g... |
Diabetic retinopathy is the most common complication in diabetes.1,2 it is a chronic, progressive, potentially sight - threatening disease of the retinal microvasculature that is associated with prolonged hyperglycemia and other conditions linked to diabetes mellitus such as hypertension.3 the threat to sight is due to... |
Most of the time, chemotherapy works in leukemia patients; however, despite high remission rate after chemotherapy, relapse always exists . Hence, it is highly necessary to find markers that enable the prediction of relapse . Monitoring minimal residue disease (mrd) is an important clinical factor in the assessment of ... |
Men, aged> 30 years, with type 2 diabetes were recruited from barnsley hospital nhs trust, barnsley, u.k . Most of the subjects were recruited from the retinal screening program, which is attended by virtually all patients with diabetes in the barnsley area . Subjects were given written and verbal information regarding... |
Techniques involving solid supports play crucial roles in the development of genomics, proteomics, and in molecular biology . However, solid - phase tools have been employed to a much lesser extent in glycobiology and glycomics . There are a number of classical methods for immobilization of mono- and oligosaccharides t... |
Although the incidence of mets is known to depend on lifestyle, diet, and physical activity,1,2 it is also suggested that genetic factors may play an important role . For example, the risk for mets may be increased by the presence of common snps within the fto - associated gene, the mc4r gene, and the ppar gene . As th... |
Since the breakthrough discovery of the obligatory role of the vascular endothelial cells by furchgott and zawadzki in 1980, endothelial pathophysiology has been intensely investigated, and the term " endothelial dysfunction " has been referred to in the scientific literature over 50,000 times (pubmed search, may 2012)... |
Rehabilitation nutrition is a combination of both rehabilitation and nutrition care management, and this concept is used with international classification of functioning, disability and health guidelines to evaluate nutrition status and to maximize functionality in the elderly and other people with disability . Rehabil... |
Presentations vary, complications differ and yet, management remains the same, which is removal . Nothing galvanizes the team as when the code for a foreign body (fb) is communicated, especially if the case is a kid where such situation is usually encountered . Presentation is acute in vegetable foreign body aspiration... |
Postoperative pulmonary complications are found to be associated with increased morbidity and mortality following abdominal surgeries . They also lead to additional health cost and prolonged length of hospital stay . According to the findings reported in an australian study, postoperative pulmonary complications are 13... |
The majority of patients diagnosed with incompetent cervix can be treated successfully with a transvaginal cerclage . A select group of patients who have failed the vaginal approach, or have extremely short cervices, anatomically deformed cervix, deeply lacerated cervices, or severely scarred from previous failed vagin... |
Cancer is universally recognized as the century s major health concern, and its mounting escalation during the past few decades and detrimental impact on all physical, emotional, spiritual, social, and economic aspects of human life have rendered experts concerned more than ever . Of all types of cancer breasts are sym... |
Breast cancer, as the most common malignancy, is the major cause of cancer - related deaths of women worldwide [1 - 3]. Age plays a critical role in the incidence of this type of cancer, as it has been found that young breast cancer patients have worse outcomes than older premenopausal or postmenopausal patients . A la... |
Encephalitis is one cause of epilepsy in the united states, as the central nervous system (cns) trauma; however, there are 1.4 million cases of head injury in comparison with less than 50000 cases of cns infection per year . The exact etiology of this disease is unknown and might be due to infective or noninfective cau... |
Activation of mast cell degranulation has been demonstrated to be an important mediator of allergic disease and more recently, as an initiator or contributor to autoimmune disease [1 - 4]. Mast cells are granulocytes that emanate from myeloid progenitors in bone marrow and play a critical role in innate immunity as vit... |
Genetic factors significantly influence late - onset alzheimer's disease (ad) though by some estimates 3065% of the genetic variance remains unexplained by the four established ad genes (tanzi, 2012; mahley and rall, 2000). Polymorphisms of the apoe gene, specifically the epsilon 4 (4) allele, account for most of the k... |
Aneurysms of the internal carotid artery (ica) in the middle ear are uncommon vascular anomalies and are difficult to detect and treat the causes of aneurysms are multiple and include atherosclerosis and dysplastic, traumatic, and infectious lesions . Differential diagnosis should include a glomus tumor (tympanic, jugu... |
Is there a formula for turning young people from diverse backgrounds into scientists? As our country s demographics change, and as so - called minorities become majorities in many locations, it might be argued that our cultural differences make a one - size - fits - all educational strategy sound nave and even insensit... |
Calcium - dependent potassium (kca) channels are known to form complexes with voltage - gated calcium (ca) sources . These interactions are important in linking the voltage - dependent and temporal properties of ca influx to kca channel activation, allowing the kca channel to respond rapidly and effectively to ca chann... |
Ligamentous stabilizers of the knee mainly include anterior cruciate ligament (acl); posterior cruciate ligament (pcl); posterolateral complex (plc) composed of lateral collateral ligament (lcl), popliteal tendon and popliteofibular ligament; posteromedial complex (pmc) comprised of superficial medial collateral ligame... |
The defects in maxillofacial region may result due to certain disease, pathological changes, radiation, burns, trauma or surgical intervention . The case reported in this article is a large facial defect resulted from rare severe fungal infection mucormycosis . The primary objectives in rehabilitating the maxillofacial... |
. The cornea acts as a shield against external dust or microbes and prevents them to enter the eye globe . Damage or disturbance to the cornea due to scar, foreign bodies, or other diseases or disorders can lead to poor visibility . Cornea is made up of six layers which are responsible for the organization of the corne... |
Mandibular third molars are found in 90% of the general population while 33% of them having at least one impacted third molar . Mandibular third molar surgery is one of the most frequent surgical procedures carried out by oral surgeons . There are various reasons for m3 surgery such as caries and their outcomes, germin... |
Autologous peripheral blood hematopoietic cell transplantation (auto - pbhct) is a well - established therapeutic option for patients with a variety of hematologic malignancies . Mobilization of peripheral blood progenitor cells (pbpc) for auto - pbhct can be accomplished by using cytokines, most commonly granulocyte -... |
Many studies on unruptured aneurysms have reported a prevalence of approximately 3.6 to 6% and a bleeding rate of approximately 2.3 to 0.3%/year.1)18) for the giant aneurysm (25 mm), a rupture rate of 6% has been reported for one year since the first diagnosis, and based on the natural history, it was considered bad du... |
Noninvasive mechanical ventilation (niv), including noninvasive positive pressure ventilation (nippv), is a well - accepted treatment for chronic neuromuscular respiratory failure associated with conditions such as amyotrophic lateral sclerosis, and niv prolongs survival . Clinicians are often pressed for an immediate ... |
Hardware removal is indicated for infection, nonunion, failure of fixation, pain, soft tissue irritation, and anticipated strenuous activity after fracture healing [14]. During removal cases subsequent removal of broken hardware increases surgical time, and retained metalwork potentially complicates future surgeries (f... |
Nineteen isolates were multidrug - resistant (mdr), eight isolates were only resistant to inh and the remaining isolates were sensitive to both inh and rif . The bactec 460 tb system was used as the reference method for testing of the mdr isolates and the bactec mgit 960 system was used as the reference method for test... |
During storage of animal feed many different processes may occur which alter their initial natural proprieties . First of all, lipids undergo peroxidation, the process during which they are deteriorated in a free radical autocatalytic oxidation chain reaction with atmospheric oxygen . Lipid autooxidation is a cascade p... |
Seizures are the most common neurological events of childhood with approximately 35% of children experiencing a seizure at some point in their lives 25% of whom subsequently go on to develop epilepsy . The prevalence of epilepsy in india is 4.9 to 6.2 per 1000 population . Of these patients with epilepsy, 43% comprises... |
Mutations in codons 12 and 13 of kirsten rat sarcoma viral oncogene homolog (kras) and b - raf murine sarcoma viral oncogene homolog b1 (braf) genes are frequently present in tumors of patients with metastatic colorectal cancer (crc); they are observed in 30 - 45% and 5 - 20% of cases respectively 1 . Less commonly det... |
Apolipoprotein (apo) a - v - is an enigmatic modulator of plasma triacylglycerol (tg) homeostasis . Apoa - v is expressed solely in the liver and, following secretion, circulates at extremely low concentrations (~150400 ng / ml plasma). This value is approximately 10,000 fold lower than that of apoa - i, the major apo ... |
Mr images of the liver were retrospectively reviewed alongside clinical findings in 50 children and young adults with wilson's disease (m: f = 33:17; age range, 5 - 26 years; median age, 14 years). The database of the computed hospital information system was cross - referenced with the mr imaging database to identify a... |
The truth is that most medical breakthroughs have ultimately come from basic research, and i think that we as scientists need to do a better job of telling these success stories . My favorite example is that antibiotics came out of finding a random contaminant on a plate . And remember that we have crispr [clustered re... |
Systemic chemotherapy is the main treatment modality in the management of patients with metastatic disease . After chemotherapy, oncologists evaluate tumor response by observing tumor behavior, i.e. Growth, reduction or stability in its dimensions [2, 3]. Nowadays, tumor response to therapy as determined by imaging met... |
Lumbar degenerative kyphosis (ldk) is a common cause of lumbar spinal deformity in asian women aged 40 years and older . It is characterized by sagittal imbalance, a stooped posture and chronic low back pain (lbp). Associated with ldk is a loss of the normal lumbar spinal lordosis1,2,3 . Marked atrophy of lumbar extens... |
Prostate cancer (pca) is the second most common neoplasia in men worldwide, and the sixth cause of cancer - specific death worldwide . In the last 20 years, there has been a progressive increase in the global incidence of this disease . In asian countries, the incidence and mortality of pca are low and are reported to ... |
The spinal dural arteriovenous fistula (sdavf) is the most common type of spinal vascular malformation, but it is rare condition in overall incidence561013171820). It is characterized by progressive, insidious, and non - specific symptoms that are similar to those of more common etiology, such as degenerative spinal di... |
Incompetence in locating, cleaning and shaping or obturating the complete root canal system causes primary and post - treatment infections which often lead to endodontic treatment failures . However, the most significant reason for the root canal treatment failure is insufficient knowledge about the root canal morpholo... |
One of the most serious threats dental students face during their clinical training is the possibility of exposure to blood - borne pathogens, with the attendant risk of hiv . Needlestick injuries are a hazard for people who work with hypodermic syringes and other needle equipment . These injuries can occur at any time... |
Marc sprenger, director of the who s secretariat for antimicrobial resistance, recently stated that many such infections are rapidly becoming resistant to life - saving drugs;1 thus, we may be on the verge of the post - antibiotic era . Indeed, it was also proposed that many of the procedures and conditions such as sim... |
Bovine lung fragments, deep nasal swab specimens, and trans - tracheal aspiration liquids were submitted to the laboratoire dpartemental danalyses de sane - et - loire (mcon, france) and tested for classical respiratory pathogens . The unit mixte de recherche, interactions htes agents pathognes 1225 (toulouse, france),... |
Ventriculo - peritoneal (vp) shunting is the preferred and most successful method for managing congenital hydrocephalus . Abdominal complications include peritonitis, ascites, bowel obstruction, bowel and abdominal wall perforation, and inguinal herniae . An uncommon but recognized complication is formation of an abdom... |
Multiple sclerosis (ms) is a chronic inflammatory - demyelinating disease of the central nervous system (cns). It is characterised by multifocal and disseminated in time damage to the cns with heterogeneous symptomatology and the clinical course . Depending on the studied region, the prevalence in the general populatio... |
Retinopathy of prematurity (rop) is a vasoproliferative disease of the retina that affects preterm neonates and is thought to be mediated by alterations in insulin - like growth factor-1 (igf-1) and vascular endothelial growth factor (vegf). Rop is one of the major causes of avoidable childhood blindness in developed a... |
Strokes produce important physical, psychological and social consequences, in spite of advances in prevention and early care1 . Several studies highlight the importance of cognitive activities such as attention, memory and action observation on the nervous system plasticity2, 3 . The experiences and the information gen... |
Rats were subjected to a standard light - dark cycle and were maintained on a regular chow and had ad libitum access to distilled water . Indwelling catheters were placed in the right internal jugular vein and left carotid artery for infusion and sampling purposes . Rats were implanted with bilateral intrahypothalamic ... |
Because double stranded (ds) dna cleavage is much harder to repair than single stranded (ss) dna cleavage, ds damage is particularly efficient in inducing self - programmed cell death or apoptosis . These compounds, often hailed as the most potent family of anticancer agents, produce cleavage of both strands of dna dup... |
The study was conducted at the drug deaddiction and treatment center (ddtc), department of psychiatry, postgraduate institute of medical education and research (pgimer), chandigarh - a multispecialty tertiary - care teaching hospital providing services to a major area of north india . Patients with any substance depend... |
Organizations increasingly use teams to do their work which was traditionally given to individuals (1). The reason why organizations seek teamwork is that teams can, in most cases, be more successful than individuals who work alone . More effective and better decisions can be made when people work together (2). Moreove... |
The receptor for advanced glycation end products (rage) is a cell surface receptor of immunoglobulin superfamily . Rage activation through ligand binding can induce chronic inflammation and oxidative stress, and it has been linked with diseases like diabetic complications, cardiovascular and neurodegenerative diseases,... |
Radicular low back pain is one of the most common medical problems that cause decreased work competence and a heavy cost . Accurate diagnosis of this radicular pain has a paramount important role in proper treatment planning . History taking and physical examination are the first steps in diagnosis of lower extremity r... |
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