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Psoriasis is a chronic immunologically - based inflammatory skin disease which affects approximately 2% of the general population [1, 2]. The presence of an unknown antigen causes the generation of effector t cells that infiltrate the skin and initiate a pathogenetic process by producing different types of cytokines . ...
Congenital causes of intestinal obstruction include duodenal atresia, malrotation, duodenal obstruction from ladd bands, other congenital bands, superior mesentery artery syndrome, enteric duplications as well as several other entities . Congenital anomalous bands resulting in proximal jejunal obstruction are a rare en...
In generalized ligamentous laxity, the range of motion across various joints in an individual is increased compared to the mean range of motion in the general population (1). Although this could occur as a result of genetic disorders affecting the connective tissue, in most individuals there is no genetic aberrancy and...
Data types and tools evolve, predictive approaches developed for such work can also be directed at a number of closely connected issues . Some of these include taking advantage in motif discovery of increasing numbers of genomes, including low - coverage sequences; quantifying the contributions to motif discovery of di...
G. v. black was the first to describe a systematic method of cavity preparation and the ideal cavity form to restore carious lesions . Classical cavity forms and principles remained appropriate and largely unchallenged for a period of 50 years using amalgam . Amalgam has been the most widely used dental restorative mat...
All procedures were approved by the animal care and use committee of boston children s hospital . We performed complete blood count and wright - geimsa analyses on peripheral blood recovered from adult pnt . Genetic mapping and positional cloning were utilized to identify zgc: 162207 (atpif1a) as the candidate gene for...
We now appreciate that the immune system recognizes cancer and that patients with strong natural immune reactions have better survival compared with those with weak responses . This concept was first demonstrated in patients with colorectal cancer (crc) by pages et al . Here they demonstrated that the immune contexture...
Experimental groups of 20 (4- to 6-week old) c57bl/6 female mice (charles river, l'arbresle, france) were injected intracerebrally with 20 l of 10% (weight / volume) homogenates per mouse prepared from brain stem samples of 3 cattle tse isolates . Two of the isolates were characterized, as previously described (7), by ...
Cancer is the important cause of death in many countries (1), including iran (2). In fact, cancer, being a life - threatening disease, makes the inevitable need for the implementation of an effective end - of - life care strategy in health care services more than ever (3). Physicians should consider the patients best i...
A 1997 national pediatric database in the united states was reviewed and found that 84,202 children were hospitalized with orthopedic trauma and tibia and/or fibula fracture accounted for 18,111 (21.5%). This indicates that in the pediatric orthopedic trauma setting, fractures of the tibia and/or fibula are the second ...
Opls - aa force field parameters and the tip3p model(22) are employed for potentials of alanine dipeptide and water, respectively . The first - order ermak and mccammon algorithm(1) is implemented in bd simulationswhere dt is a time step, di is the diffusion coefficient of atom i, and xi is a random noise vector obtain...
Type 1 autoimmune hepatitis (aih) is a progressive liver disorder predominantly affecting women that is characterized by the presence of circulating autoantibodies [anti - nuclear antibody (ana) and/or anti - smooth muscle antibody (asma)], hypergammaglobulinemia, and a favorable response to immunosuppressive therapy (...
We conducted a preliminary screening of the 16s rrna methylase - producing bacilli on our gram - negative microbial stock of 2,877 strains isolated from japanese hospitals within the past several years . Arbekacin, a semisynthetic aminoglycoside belonging to the kanamycin group, requires 2 modifications at the (6) amin...
Deep brain stimulation (dbs) is a neurosurgical technique aimed at improving functional neurologic disorders . To facilitate intraoperative neurophysiologic microelectrode recording (mer) and neurocognitive testing of the eloquent parts of the brain, dbs is commonly performed via an awake approach under a local anesthe...
There are no p waves and the rhythm is irregularly irregular, with a variable ventricular rate between 110 and 160 bpm . The qrs complexes are usually <120 ms unless there are preexisting bundle branch block, accessory pathway, or rate - related aberrant conduction . Fibrillatory waves, small, irregular waves seen as a...
These two clinical entities are observed over time as separate diseases . Epidemiological and clinical evidence, as well as experimental observations have suggested a link between rhinitis and asthma leading to a definition of allergic rhino - bronchitis or united airways diseases and the concept of one airway one dise...
In 1935, rous and beard were the first to describe the progression of virus - induced papillomas to carcinomas in rabbits 1 . During subsequent decades, it has been widely accepted that the development of human cancer follows a multi - stage process involving tumor initiation, promotion and progression 2 . These stages...
Ridge augmentation refers to the procedure that was performed for cases with insufficient vertical or horizontal volume of bone to augment the height or width of the alveolar ridge by executing particulated or block bone graft . Ridge augmentation is a type of onlay graft, and thus, the possibility of bone resorption a...
Reinforced surveillance systems aimed at monitoring the introduction of chikv have been implemented in 6 departments in southeastern france, including the var department, where ae . Albopictus has spread since its introduction in 2004, presumably from northern italy (4). On august 29, 2010, a 7-year - old girl (patient...
Cd47 (originally named integrin - associated protein (iap)) is a cell surface protein of the immunoglobulin (ig) superfamily, which is heavily glycosylated and expressed by virtually all cells in the body . Cd47 was first recognized as a 50 kda protein associated and copurified with the v 3 integrin in placenta and neu...
Dentine bonding agents are bonding agents that consist of 3 parts: (i) an acid that removes the smear layer accumulated on the dentine and that helps increase the microporosity of the enamel (etching step), (ii) a substance that enhances the flow of bonding agents into the dentine and increasing the microporosity of th...
In general, brain injury can occur due to sudden and severe head strike to a hard object, which can be mild, moderate or severe (1). The main causes of head injury include traffic accidents, falling from heights, physical violence, accidents at work, inside home accidents and during exercise incidents . However, the mo...
Formalin - fixed, paraffin - embedded tissue samples from 61 patients with primary localized esfts were obtained in korea, brazil, and argentina . Fifty - five of the 61 tissue samples were obtained by surgical biopsy and the other six were obtained by surgical excision . At the time of tissue sampling, none of the pat...
Rhabdomyosarcoma (rms) was first described by weber in 1854, is a malignant soft tissue neoplasm of the skeletal muscle origin . The most common sites of involvement of rms are head and neck, genitourinary tract, retroperitoneum, and extremities . Clinically, the manifestations of rms may vary from a small cutaneous no...
The human lmo2 gene was first cloned from an acute t lymphocytic leukemia (t - all) patient with an (11;14)(p13;q11) translocation . It was a pivotal factor for both embryonic and adult hematopoiesis, as well as angiogenesis . Moreover, lmo2 is expressed in all hematopoietic cells except for mature t cells, and its for...
The demand for food of animal origin increases each year . To satisfy this demand, livestock production within the european union (eu) in 2011 was approximately 10 million heads of goats, 80 million heads of sheep, 80 million heads of cattle, and 150 million heads of pigs . To produce safe and nutritional food products...
Oral squamous cell carcinoma (oscc) is one of the most aggressive malignancies worldwide and accounts for more than 90% of all oral cancers . It is ranked as the sixth leading cause of cancer mortality worldwide and the second leading cause of cancer mortality in india . The most common sites of oscc are the lateral ve...
This study was performed as a part of the prospective ongoing research on the positioning of chronic kidney disease in specific health check and guidance in japan project . A new annual health check program, the specific health check and guidance in japan, was started by the japanese government in 2008, targeting early...
However, a trans - placental and respiratory route of infection has been reported in rabbits, too (4). Rabbits suffering from encephalitozoonosis show various clinical signs, and most infections are initially asymptomatic until sudden death . Many rabbits infected with e. cuniculi subsequently develop renal failure, ey...
Alterations in the influence of inhibitory gabaergic circuits can have a profound impact on the excitability of neural network function, and have been associated with hyperexcitable conditions such as epilepsy [1, 2]. Recent work has identified what may be one of the most important processes in ensuring that networks m...
The lake malawi cichlid fauna comprises over 800 species offering a spectacular example of adaptive radiation with virtually all niches in the lake being filled by members of this family [2, 3]. With a few exceptions, all lake malawi cichlids form a monophyletic group as supported by mitochondrial [46] and nuclear ([79...
The online version of this article (doi:10.1007/s13300 - 014 - 0066-y) contains supplementary material, which is available to authorized users . Supplementary material 1 (pdf 190 kb) supplementary material 1 (pdf 190 kb) andrea messori, valeria fadda, dario maratea, sabrina trippoli and claudio marinai declare no confl...
Who has estimated that there were 171 million people worldwide with diabetes mellitus (dm) in 2000 and predicted that 366 million people will have dm by 2030 . The united states centers for disease control and prevention have estimated that 13 million persons in the united states have diagnosed dm, and an additional 5,...
Several attempts have been made to address this problem such as diet changes, lowering carbohydrate intake, efficient oral hygiene measures and rinsing fluoride mouthwashes . Application of sealants, fluoride releasing bonding agents, elastic modules impregnated with fluoride and fluoride varnishes are the most commonl...
Many of the ligands trigger costimulatory growth signals in primary cells, lead to the activation of nuclear factor (nf)-b, or even induce cell death . A proliferation - inducing ligand (april) the development of cancer is viewed as a multistep process involving mutation and progressive selection for cells with increas...
Neonatal intestinal perforation (nip) is an extremely rare complication of intestinal hemangioma (ih). Neonates younger than 30 days and having perforation include more common etiologies such as necrotizing enterocolitis, meconium ileus, and spontaneous idiopathic as well as gastric perforation.1 nip has been associate...
Prostate cancer is a common health problem that in the majority of cases starts to develop at the age of 50 years, reaching its peak at 6070 years of age . A variation in its incidence and prevalence exists between western, asian and arabic populations . The highest incidence is in the usa and canada followed by europe...
The supporting cells of the organ of corti are structurally and electrically coupled together by gap junctions (jahnke, 1975; gulley and reese, 1976; iurato et al ., 1976; hama and saito, 1977; santos - sacchi and dallos, 1983; kikuchi et al ., 1995). Such gap junctional coupling among the supporting cells provides for...
Delirium caused by somatic factors is a widespread and dangerous problem associated with the aging of the population . It has been reported that consciousness disorders are experienced by 10 - 15% of patients on general wards and up to 50% of patients admitted emergently to geriatric wards . The frequent occurrence of ...
Fixed drug eruption (fde) is characterized by recurrent well - defined lesions in the same location each time the responsible drug is taken . We report here a rare case of fde induced by atenolol, a beta - adrenoreceptor - blocking agent . A 48-year - old tunisian woman was referred to our department for the appearance...
Natural orifice translumenal endoscopic surgery (notes) has developed rapidly in recent years, and transvaginal cholecystectomy has been successfully performed in humans . Researchers are actively evaluating different peritoneal accesses and development of novel instruments and innovative procedures . There have been f...
Hepatocellular carcinoma (hcc) is the fifth most common malignancy worldwide.1 in malaysia, hcc is the thirteenth most common cancer affecting the population.2 the etiology of liver cancer is multi factorial; some of the well known risk factors include hepatitis b and c viral infection, exposure to chemicals such as ar...
Transcatheter closure of patent ductus arteriosus (pda) by use of the amplatzer duct occluder shows good results in properly selected patients.1 the advantages of the amplatzer duct occluder device include a user - friendly delivery system, the ability to retrieve or reposition the device when required, and a high comp...
Schizophrenia is a chronic, heterogeneous, severe mental illness with impairments in biological, psychological, and social functions . Even though the mode of inheritance in schizophrenia is complex and primarily nonmendelian, it is well established that the schizophrenia has a high heritability . Endophenotypes, descr...
Post - operative radiotherapy is an established adjuvant treatment after radical hysterectomy with intermediate- and high - risk early - stage cervical cancer patients [1, 2]. A conventional radiation technique for post - operative cervical cancer patients is whole - pelvic radiation therapy (wprt) requiring four stati...
Maternal depression has adverse effects on infant behavioral, emotional, and cognitive development [17]. Studies investigating the impact of postpartum depression on child development have largely relied on correlative studies in humans . However, investigation into the mechanisms mediating the transmission of negative...
Increasingly, gerontological researchers, practitioners, policy makers, and planners are concerning themselves with the growing importance of aging in place . Aging in place does not have one single definition but broadly is considered to be the ability to continue to live in the environment of one's choice, even when ...
Lotus (nelumbo nucifera) belongs to the family of nelumbonaceae, all parts of which are edible in various forms . It is generally consumed as vegetable; chiefly the stem part is processed in different forms such as roasted, pickled, dried, and fried . The plant exhibits multiple nutritional and medicinal properties, he...
In this study we present a methodology for the direct sequencing of brca genes through a simple workflow implementable in a diagnostic lab . Most tumors are considered sporadic, whereas the remaining 510% is inherited as autosomal dominant disease and defined as hereditary breast and ovarian cancer (hboc). Brca1 and br...
This is a non - controlled, longitudinal study, carried out in a sample of 150 children 12 - 15 months of age in three health units of the municipality of rio de janeiro who received the combined mmr vaccine according to the basic immunisation schedule and nip routine procedures . Healthy male and female children, livi...
It is now considered that approximately 10% to 15% of the adult population has gallstones . Age, sex, diet, sudden weight loss, etc . According to the report of the us national institute of health, it is estimated that 6.3 million men and 14.2 million women, aged 20 - 74 years in the united states has calculosis of the...
Cardiac resynchronization therapy (crt) is an important device - based, non - pharmacological approach that has shown to improve the outcome in selected patients with chronic heart failure (hf). Large randomized trials have demonstrated that crt improves left ventricular (lv) function and reduces both morbidity and mor...
A 52-year - old previously healthy male patient visited the emergency department of a local clinic due to dyspnea with the recent onset of chest pain . An emergency coronary angiogram (cag), which was prompted by a 12 lead ekg study suggesting precordial lead st segment elevation myocardial infarction revealed a totall...
Ganglioside may influence growth and cell - to - cell interactions may be of importance in the development of malignancy . In the present study, we used a transplantable murine hepatoma as the experimental model, and treated the animals with 5-fluorouracil (5-fu) as the active therapeutic drug to determine the membrane...
Cardiac disease and hypertension have been the third and eighth leading causes of death in taiwan since 2000 . According to a recent study, the percentage of the population with a prescription for antihypertensive drugs in taiwan has increased from 2001 to 2006 . The authors of this study report that during this period...
Most cases of spontaneous rupture of the renal pelvis and ureter are associated with ureteral obstruction by calculi . Although uterine cervical cancer is an exceedingly rare cause of renal pelvic or ureteral rupture, several cases have been reported (singh et al ., 2009, mcclinton et al ., 1989, spurlock et al ., 1987...
Carcinomas producing granulocyte colony - stimulating factor (g - csf) are extremely malignant and have a poor prognosis [1, 2]. Thus, a liposarcoma producing g - csf is particularly rare and has only been described in a few case reports [1, 3]. Here, the tumor also showed spontaneous rupture, which has not been previo...
Flynn et al ., reported the incidence of cubitus varus deformity after treatment was 5%, whereas arino et al ., reported that it was almost 21%, ulnar nerve deficit was found in 15% of patients who were treated with medial and lateral pin as per the report of chai.2345 many different methods are described such as close...
Cervix cancer is one of the leading causes of cancer morbidity among women worldwide and it is the second most common cancer among women in developing countries . Except for early stage, cancer cervix is usually treated with radiotherapy which consists of external beam radiotherapy followed by intracavitary brachythera...
Several factors have been associated with this trend range from changes in the physical, social and economic way of life and environments of the people, to genetic and physiologic factors . Education is one of the media that influences greatly the attitude, social, economic and physiologic behaviors of the people . Man...
Nevertheless, they propagate the high tie technique since it allows better lymph node retrieval and therefore a more accurate tumour staging . In another review comparing the low tie with the high tie technique, lange et al . Nevertheless, they favour the low tie technique since it is less invasive, also with regard to...
The main purpose of restorative dentistry is to restore and maintain tooth health by an adequate restorative treatment in order to protect and re - establish pulp function . Pulp plays an important role in the formation and nutrition of dentin as well as in the inervation and defense of the teeth (figure 1). The primar...
Infarct of the anterior spinal artery is the most common subtype of spinal cord infarct, and is characterized by bilateral motor deficits with spinothalamic sensory deficits . We experienced a case with atypical anterior - spinal - artery infarct that presented with bilateral hand weakness but without sensory deficits ...
The prevalence of obesity in children and adolescents is increasing world - wide, notably in developing countries . Now - a - days, this problem has become one of the important concerns about general health at the global level . Obesity in childhood and adolescence has different effects on mental health, including symp...
Despite the significant improvement in adhesive systems, they are not capable of preventing the formation of microgaps at the dentinal margins of composite restorations . Even when immediate complete marginal sealing was established, degradation of resin - dentin interface can occur rapidly over time . Also, the plaque...
Striated muscle cells contain a complex, highly ordered cytoskeleton, mainly composed of interdigitating thick myosin and thin actin filaments . Muscle contraction and relaxation occurs by the sliding of myosin filaments past actin filaments under the strict regulation of their accessory proteins, which are responsible...
The converge consortium has obtained a large number of samples (including 5,303 cases of mdd and 5,337 controls, all chinese subjects) for inclusion in genome - wide association studies (gwas). Snp rs35936514 in the lhpp gene has been reported to be significantly associated with mdd at a genome - wide level . Lhpp enco...
It was a blend of 19th century american metaphysical culture . In that cultural milieu, metaphysics had to do with the individual and universe communing through energetic and spiritual harmony . The combination of worldviews and the practices that went along with them are often described in terms of colliding worldview...
Cystinuria is an autosomal recessive disorder characterized by the abnormal urinary excretion of cysteine and the dibasic amino acids in the renal tubule and epithelial cells of small intestine . Two genes including slc3a1 and slc7a9 are associated with cystinuria and two different types of cystinuria have been known a...
A sample of 296 wives was randomly selected from a database at the iranian martyrs and veterans affairs foundation there were 139 wives of prisoners of war; 60 wives of martyrs, whose husbands were killed during the war; and 97 wives of disabled veterans (according to imvaf classification, based on the severity of the ...
The dietary magnesium intake tends to be lower than that recommended worldwide even in western countries . Several factors have been identified to be trigger for lowering magnesium intake including the waterborne magnesium factor, the loss of magnesium during food refining, and the magnesium content of vegetarian diets...
Human papillomavirus (hpv) is the most common sexually transmitted infection (sti) among young adult women, and it plays a critical role in the development of cervical cancer [1, 2]. Biologic susceptibility to hpv acquisition and immune competence for clearance of an hpv infection could be affected by common, treatable...
Psychobehavioral approaches attempt to identify the underlying cognitive dissonance creating the intense emotional discomfort that can trigger seizures . A recent review of psychobehavioral therapy for epilepsy recommends case reports as a research design to explore specific psychological mediators of seizure self - co...
Nowadays, new treatments for schizophrenia are more ambitious, aiming to improve not only psychotic symptoms, but also quality of life and social reinsertion . We briefly but critically outline advances in the treatment of schizophrenia from the mid-1970s up to the present . For many years, it was widely accepted that ...
Asthma is a chronic lung disease which causes breathing difficulties because of chronic airway inflammation . Asthma is a common health problem around the world, and its prevalence also has been increasing in korea . The pathogenesis of asthma is unknown and there are no exact biomarkers to diagnosis asthma . In recent...
In 2007, the world health organization (who) launched its initiative for the global elimination of congenital syphilis, with the goal that by 2015 at least 90% of pregnant women are tested for syphilis and at least 90% of seropositive pregnant women receive adequate treatment . Subsequently in september 2010, paho memb...
In recent years, several neuroimaging techniques have been employed to investigate the neural activity associated with motor imagery and the illusion of motion . The human brain is able to recognize changes in limb position and movement from both visual and somatosensory stimuli, and the information conveyed to the bra...
Posterior chamber phakic intraocular lens (piol) implantation is generally accepted as an effective and reversible treatment method for high myopia with preservation of lens - regulating capability . In the ophthalmology clinic, the implantable collamer lens (icl, staar surgical, nidau, switzerland) is the main posteri...
Since the middle of the 1990s, numerous mergers and consolidations have taken place in the health insurance industry . In fact, the annual number of mergers among managed care companies averaged 43 during the 19942005 period and ranged from a low of 27 in 1995 to a high of 66 in 1996 (kaiser family foundation). Economi...
Polycystic ovary syndrome (pcos), a heterogeneous condition associated with irregular menstrual cycles and androgen excess, is a common gynecological endocrine disorder affecting 6%-12% of premenopausal women . Since the national institutes of health (nih) sponsored conference on pcos in 1990, it has become appreciated...
Pancreatitis is a major well - known complication of endoscopic retrograde cholangiopancreatography (ercp) with reported incidence ranging from 1% to 10% in various series [1 - 3]. But the most accepted theory is mechanical trauma to papilla or pancreatic sphincter causing transient obstruction to outflow of pancreatic...
Systemic lupus erythematosus (sle) is a systemic autoimmune disease with manifestations in multiorgans that are induced by the deposition of circulating autoantibody - autoantigen complexes (immune complexes, ic) and amplified by subsequent infiltration of different types of leukocytes promoting the inflammation . Lupu...
Bowel endometriosis occurs in approximately 10% of all patients with endometriosis and usually arises from the rectum and sigmoid colon at a rate of approximately 80% . Conservative treatment with hormonal therapy is usually performed . However, if the patient hopes to become pregnant, an alternative to long - term hor...
The treatment of hepatitis c virus (hcv) infection has evolved from peginterferon alfa (pegifn) plus ribavirin (rbv)based regimens to combinations of alloral, directacting antivirals (daa), including daclatasvir a pangenotypic ns5a inhibitor (hcv genotypes 16 in vitro) and the ns3 protease inhibitor, asunaprevir (activ...
Andropause, androgen decline in the aging male (adam), or testosterone deficiency syndrome (tds) is a true clinical entity characterized by symptoms of erectile dysfunction, decreased libido, osteoporosis, and general weakness . However, its occurrence is still poorly documented and most literature is from european or ...
Early detection of metastasis is one of the aims of follow - up examination in patients with malignant melanoma since once metastasized, despite a variety of therapeutic options e. g. chemo- and/or immunotherapy, patients suffering from malignant melanoma show an unfavorable prognosis . Therefore, it would be most desi...
One problem may be that it is difficult to present a comprehensive picture of the scope of the problem assessable to other than clinical experts . Resistance is a global phenomenon involving many types of infections, bacteria and substances and data are scarce, particularly so in developing countries . Nevertheless, us...
The delicate catheter ablation of atrial fibrillation (af) involves a relevant risk of major complications although mortality is less than 1 in 2000,, . Patients undergoing catheter ablation for af are required to lie motionless on the procedure table for several hours, and repeated stimuli from ablation are sometimes ...
The study was conducted at an intensive 4-day teaching program for final - year ophthalmology residents, held at hubli, karnataka state, south india, in january 2014 . The questionnaire used in this survey was developed and validated in consultation with the division of research and patents of the parent institute of t...
Failure to achieve satisfactory weight loss has been reported in several series of morbidly obese patients who underwent bariatric procedures . The result of inferior weight loss after roux - en - y gastric bypass (rygb) in high body mass index (bmi) patients has led to the development of biliopancreatic diversion with...
The ewing sarcoma family of tumors, including ewing sarcoma and the more differentiated counterpart, primitive neuroectodermal tumor, are the second most common primary malignancies of bone in childhood and adolescence but can also occur in the soft tissues . Systemic chemotherapy is aimed at treating known or micromet...
Telomeres are specific sections of dna at the end of chromosomes comprised of tandem dna repeats (ttaggg). Their biological role is to prevent dna shortening, protect chromosomes from inappropriate dna fusions, as well as dna breaks in order to maintain genomic integrity and stability (1). Importantly, upon each cell d...
Progressive neurologic deterioration or back and leg pain in children with a history of myelomeningocele (mmc) surgery may be due to cord tethering or growth of an intradural inclusion tumor . Loss of motor function in the lower extremities, gait abnormality, back or leg pain, scoliosis, and foot deformity are common f...
Insulin resistance is a key feature of obesity and is involved in the development of type 2 diabetes, fatty liver disease, cardiovascular disease, and cancer,,, . Insulin resistance is associated with altered production of several adipokines (i.e. Bioactive secreted products from adipocytes) that regulate insulin sensi...
Radiotherapy has been proven to successfully treat local and regional neoplasic lesions but it may adversely impact on normal tissues . High vulnerability to irradiation was already documented in various bone tissues (pelvis, sternum, vertebra, clavicle, femoral head, and mandible) with subsequent deleterious effect on...
Recent advances in obstetrical and neonatal intensive care management have increased the survival rates of very low birth weight infants . In these infants, artificial ventilation is related to potential iatrogenic lung damage and therefore reduced to a minimum . The introduction of new strategies of surfactant therapy...
Hemophagocytic lymphohistiocytosis (hlh) secondary to infectious disease is an important entity especially in tropics where infectious diseases are rampant and still pose a major threat . A timely diagnosis and prompt treatment can improve the clinical outcome of this otherwise potentially fatal condition! This article...
The management of patients with coagulopathic disorders undergoing orthopaedic surgery requires a dedicated, multi - disciplinary team with detailed perioperative planning . Bernard - soulier syndrome (bss) is an extremely rare disorder, affecting 1 in 1 million individuals worldwide . It is caused by a deficiency in g...
It is known that such exacerbation is typically associated with an increase in neutrophilic (and, to a lesser extent, eosinophilic) airway inflammation.1,2 however, copd exacerbations are heterogeneous in terms of both airway inflammation and etiology . As expected, the bacterial cluster was the largest, but the eosino...
Nephrotic syndrome with the deposition of non - amyloidal fibril structures in the glomeruli was first reported in 1977 by rosenmann et al ., and the term fibrillary glomerulonephritis (fgn) has been used since 1987 . Fgn is a rare glomerular deposition disease and accounts for approximately 0.51.0% of all adult glomer...