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Liquid - based cytology (lbc) as a technique was introduced and tried on pap smears . Thereafter, this technique was performed for non - gynecological cytology, including conventional fine needle aspiration cytology (fnac), guided fnac and fluid cytology . The thin - prep (tp) smears were consistently devoid of obscuri... |
Eligible subjects were healthy individuals who voluntarily received routine comprehensive health check - ups, including computed tomography (ct) scan analyses of abdominal adipose tissue, from january to december 2008 at the seoul national university hospital healthcare system gangnam center . Data were collected throu... |
Recurrent aphthous stomatitis (ras) is the most common recurrent lesion of the oral epithelium . The prevalence of ras was reported to be 40% in a population of children of the united states . A prevalence of 31 - 36% has been reported for ras among medical and dental students, compared with 10 - 20% in the general pop... |
These studies have documented that diabetic cornea is vulnerable to many abnormalities such as corneal endothelial damage, recurrent corneal erosions, punctate epithelial keratopathy, persistent epithelial defects, impaired corneal sensitivity, ulcers, slowed wound repair, and superficial keratitis.13 morphological fea... |
Microbial control in the endodontic system represents a challenge to the solution of refractory infections when chemical and surgical procedures do not provide the desired response for control of infection . The chemomechanical preparation used during endodontic therapy is the main factor responsible for eliminating th... |
The study protocol was approved by the ethics committee of the ministry of health and the school boards . A total number of 30 clusters including 7,493 girls (aged 620 years) were selected . Students with a history of acute or chronic diseases or any chronic medication use were excluded . In all subjects, height, weigh... |
Ubiquitination is a process in which one or multiple ubiquitin moieties are covalently attached to a substrate through an enzymatic cascade involving ubiquitin - activating enzyme (e1), ubiquitin - carrier protein (e2), and ubiquitin - protein ligase (e3). Formation of a ubiquitin lys48 chain on the -nh2 group of a sub... |
The south american sea lions (otaria flavescens, carnivora: otariidae) are common pinnipeds living along the eastern and western coasts of south america and are generally found in peru, chile, argentina, and south brazil [16]. Along the chilean coastal shores, more than 200 colonies of free - ranging sea lions a vast a... |
In 2014, the szent - gyrgyi prize for progress in cancer research was awarded to james allison, phd, chairman of the department of immunology at the university of texas md anderson cancer center (figure 3). Allison's pioneering cancer research in the area of immunotherapy led to the successful development of immune che... |
The anterior choroidal artery (achoa) supplies several important structures including the optic tract, geniculate body, posterior limb of internal capsule, globus pallidus, cerebral peduncle, uncus, amygdala, ventrolateral nucleus of thalamus, and choroid plexus . The vascular injury of achoa may result in severe neuro... |
Transposases are enzymes that catalyze the movement of mobile genetic elements in and between genomes and are the most abundant and ubiquitous genes in nature (1). Most often, transposases are part of transposable elements (tes), which encode only the transposase gene and some short flanking sequences necessary for tra... |
Joubert syndrome (js) was initially described in 1968 in 4 siblings with agenesis of the cerebellar vermis presented with episodic hyperpnea, abnormal eye movements, ataxia, and intellectual disability1). Several years later, a pathognomonic midbrain - hindbrain malformation the molar tooth sign (mts)was detected first... |
The patient was a 77-year - old female patient admitted for surgery for the chief complaint of an intraductal carcinoma in the left breast that was diagnosed at another hospital . The plain chest radiographs taken 3 years earlier showed " no detection of abnormal findings ", and dyspnea occurred during exercise from 2 ... |
A patient with severe papulopustular rosacea (ppr) and severe background erythema responded well to a treatment regimen consisting of a short course of antibiotics in combination with a corticosteroid, followed by monotherapy with isotretinoin.in patients with very severe, inflamed disease, it is necessary to achieve a... |
The typical adult individual seen by a primary care physician most likely believes that cancer screening is a good idea, but without comprehending the trade - off of harms to benefit or the uncertainties surrounding their magnitude . The simplistic but effective mantra that early detection saves lives is one cause of t... |
H bonds in complex molecules represents a most useful but also one of the most challenging transformations in organic chemistry . Over the past two decades, notable advances in the area of chemical c h oxidation involving the use of oxidizing reagents, biomimetic supramolecular complexes, or transition metal catalysts ... |
The loss of teeth, very common in this population, is related to the reduction of bone tissue, receptors (proprioceptors and periodontal ligaments), and muscle atrophy . Consequently, orofacial functions are impaired in toothless individuals.1 in addition, prostheses are functionally less efficient when compared to ind... |
In recent years, video - assisted intubation devices have flooded theaters, and, to a lesser extent, are also being used in icus . But can such new technology really contribute to making tracheal intubation in the icu less life - threatening, or even more life - saving? Noppens and colleagues, in a study just published... |
In gipuzkoa, 27 human listeriosis episodes were reported during january 2013february 2014 . All cases produced sepsis in the patients, except 1 case that produced diarrheal disease in a 34-year - old parturient woman who had undergone a splenectomy . Eleven episodes (40.7%) occurred in pregnant or parturient women, and... |
Toothbrushes play an essential role in oral hygiene and are commonly found in both community and hospital settings . Toothbrushes may play a significant role in disease transmission and increase the risk of infection since they can serve as a reservoir for microorganisms in healthy, oral - diseased and medically ill ad... |
This article briefly reviews the need for emergency care in africa and barriers to its integration into health systems in the region . We describe an example of an emergency care initiative at muhimbili national hospital (mnh) in dar es salaam that has integrated a multi - cadre training program with development of a d... |
The notion of peripheral immune regulation by t cells that shut off other immune cells has been around for many decades (gershon and kondo, 1971)., 1995; takahashi et al ., 1998) and a lineage - specific transcription factor (hori et al ., 2003; walker et al ., 2003) confirmed the existence of a distinct regulatory t c... |
Hepatitis c virus (hcv) infection is responsible for considerable morbidity and mortality worldwide . Moreover the hcv genotype has been shown to have an important role in clinical and histological features as well as the response to antiviral treatment . Most studies suggest that subtype 1b isolate possibly represent ... |
In the past few decades, there has been a tremendous growth in information and communication technology leading to easier access to any form of digital data including medical data . Medical data are those that are generated from medical information system (mis), hospital information system (his), radiology information ... |
Septic shock is consistently the most common causative factor identified for acute kidney injury (aki) in critical illness, and has been associated with nearly 50% of cases internationally . Despite advances in our understanding of the pathophysiology of septic aki, treatment aimed at reversing or preventing septic aki... |
In modern endodontic practice, the number of indications for endodontic periapical surgery is decreasing . Still periapical surgery accounts for 3% to 10% of typical endodontic practice . This case report has been presented to emphasize that all nonvital teeth with periapical lesion should be first treated conservative... |
It has been well established that patients with end - stage renal disease (esrd) undergoing hemodialysis (hd) had a higher association of peripheral arterial disease (pad), lower extremity amputation (lea), and foot ulcerations (fu) [13]. Such an association could be attributed to a common atherosclerotic cause . Moreo... |
The neuronavigation had proven to be a great device for the surgical treatment of variable neurosurgical problems such as tumor resection or biopsy, the surgery for epilepsy, vascular neurosurgery, the localization of functional and eloquent area, spinal neurosurgery and the operation for hydrocephalus9,13,16,17). Beca... |
One hundred forty - seven clinical isolates of m. tuberculosis were obtained from the molecular mycobacteriology laboratory, department of microbiology, faculty of medicine, siriraj hospital, mahidol university, thailand, and the t-2 project from 1997 to 2001 (table). These strains were isolated from 74 cerebrospinal f... |
Although, the incidence of multicentricglioma accounts nearly 2.5% of all gliomas, mostcases are glioblastoma or anaplastic gliomas . Oligodendroglioma cells are detectablein the cerebrospinal fluid in up to 14% of patients, and we recently treated a case of multiple anaplastic oligodendrogliomas, describe the case in ... |
Metformin is widely used to improve insulin resistance (ir), but the mechanism is not fully understood . Although liver is the primary target, metformin acts on a variety of tissues, including adipose tissue, skeletal muscles, endothelium, and ovary [1, 2]. Previous studies have demonstrated metformin exerts the metabo... |
Efforts in the field of biomarker research have pointed to the existence of circulating immune complexes as a novel class of tumor markers with diagnostic potential comparable with or greater than that of the corresponding free biomarker . They include biomarker - immunoglobulin m (igm) complexes, which have been found... |
The design and baseline characteristics of the whi have been described in detail elsewhere (8). In brief, the whi enrolled postmenopausal women 5079 years of age who provided written informed consent and had an expected survival and local residency of 3 years . Exclusion criteria included current alcoholism, drug depen... |
Cholelithiasis presented as chronic right back pain in the case discussed in this report . According to the clinical practice guidelines, gallbladder lithiasis is a common condition . Around two - thirds of the cases are asymptomatic, with the most frequent clinical presentation being the presence of attacks of acute a... |
The process of odontogenesis is under the control of homeobox (hox) genes; a number of different mesenchymal regulatory molecules and their receptors . Hox genes are classified as muscle segment (msx1 and msx2), distal - less (dlx), orthodontical, goosecoid, paired box gene 9 (pax9) and sonic hedgehog (shh). Msx1 and m... |
Homeopathy claims a curative reaction from a small dose of a drug of which high doses cause symptoms similar to those from which the patient is suffering . Homeopathy originated in 19 century, prior to the acceptance of the germ and gene bases of disease; it has never been based on scientific evidence . Results of rand... |
Testicular adrenal rest tumors (tarts) are benign intratesticular masses that occur in male patients with congenital adrenal hyperplasia (cah), with more than 90% of cases caused by a deficiency of 21--hydroxylase . Tarts originate from aberrant adrenal cells in the testes and can impair both spermatogenesis and endocr... |
Hip fractures are a major problem for the elderly, and especially for those confined to long - term care, both nursing homes and residential homes . Those in institutions constitute about 6%-7% of the population of those over 65 years, but this population contributes almost one third of the hip fracture numbers [1, 2].... |
Angiogenesis is a constant hallmark of multiple myeloma (mm) progression and has prognostic potential . We have previously isolated endothelial cells (ec) from bone marrow of patients with mm (mmec). They show intrinsic angiogenic ability, because they rapidly form a capillary network in vitro, and extrinsic ability, b... |
Preeclampsia, a pregnancy - complicated syndrome, is one of the leading causes of maternal and fetal morbidity and mortality . This potentially dangerous condition affects approximately 27% of all pregnancies in the western world, but the incidence in developing countries can be greater [1, 2]. Preeclampsia is a matern... |
Spending hours in plastic surgery opd in a government medical college and dealing with the kind of queries posed to us by patients and often having to see delayed and neglected patients made us question and wonder on various views that people have of plastic surgery . Most of the patients had no idea of the range of ou... |
This mixed - methods study (yin, 2003) seeks to more accurately identify perceptions of acceptance for various age-, race-, and sexual identity - based segments of the population within the gay and mainstream communities at a pivotal time in the evolution of both urban gay communities and mainstream societal attitudes ... |
According to the international diabetes federation, metabolic syndrome (ms) is clinically characterized by central obesity (waist circumference 94 cm for men and 80 cm for women), and at least two of these risk factors: high triglyceride levels (150 mg / dl); low hdl cholesterol (40mg / dl); high blood pressure levels ... |
The prostate is the site of two common diseases in aging men, benign prostatic hyperplasia and prostate cancer (pca). Epidemiological studies show that, in the united states, pca accounts for 28.7% of new non - skin cancers and 12.7% of cancer - related deaths.1 androgen deprivation therapy (adt) retards pca progressio... |
5xfad tg mouse model (b6sjl - tg(appswfllon, psen1*m146l*l286v)6799vas) (jackson laboratories) is bred on a non - transgenic background (b6sjlf1). Hela is a human cervical cancer cell line; nih/3t3s is a mouse embryonic fibroblast line; hepg3 is from hepatocellular carcinoma; raw264.7 is a mouse leukemic monocyte macro... |
Cataract extraction requires analgesia, ocular akinesia, and is performed in the outpatient surgery . Topical anesthesia is indicated in procedures involving the anterior part of the eye, lasting less than two hours . Sedation is performed so that the patients remain quiet and do not interfere with the procedure . Clon... |
The prevalence of childhood obesity has been increasing at unsettling rates across the globe . In addition to striking the developed world, this pattern has also been noted in developing countries undergoing rapid epidemiological transitions, including those in east africa . In sudan, a study of children in secondary s... |
Incisional hernia is a common long - term complication of abdominal surgery and is estimated to occur in 3% to 13% of laparotomy incisions . However, its incidence is greater than 23% in patients who have developed an infection in the laparotomy wound . Approximately 50% of incisional hernias develop within the first 2... |
5-fluoruracil (5-fu), pyrimidine antimetabolite, is a chemotherapeutic agent widely used for various tumors . Neurotoxicites of 5-fu with manifestations of somnolence, upper motor neuronal signs, cerebellar ataxia and a cluster of symptoms and signs of organic brain syndrome have rarely been reported . We report a case... |
Most patients are asymptomatic or suffer from mild symptoms only, (1) and many present with extraintestinal manifestations such as neurologic disorders (2). The anti - tissue transglutaminase antibody (ttga) test is a sensitive and specific tool in disclosing celiac disease with overt villous atrophy (3) with a specifi... |
We carried out a retrospective study by testing blood and serum samples on 1,740 patients who consulted the emergency department of cayenne hospital seeking treatment for fever compatible with malaria and/or dengue during a 1-year period, july 2004june 2005 (figure). Diagnosis of malaria has always been quick; dengue d... |
To date, kaposi sarcoma has not been mentioned among the adverse effects of triptolide / tripdiolide, ethyl acetate extracts or polyglycosides of the chinese herbal remedy tripterygium wilfordii hook f. she underwent treatment with corticosteroids, methotrexate and gold sodium thiosulfate, and was chronically taking ke... |
. One of the most common cardiac diseases is congestive heart failure, with the highest incidence, mortality, and hospitalization . This is the only cardiac disease with a progressive incidence and mortality, in which almost 10% of the individuals over 75 years of age are involved . The reported statistics reveal an in... |
Vaccinations are an effective prevention tool for maintaining the health of the individual and society as a whole and have significantly increased life expectancy and quality [1, 2]. Smallpox was officially declared eradicated by the world health organization (who) in 1980, all industrialized countries are considered "... |
One of the leading causes of death are non - communicable diseases (ncds), killing more people each year than all other causes combined . It has been reported that nearly 80% of ncd deaths occur in low- and middle- income countries . It has been estimated that about one fourth of global ncd - related deaths take place ... |
Lysosomes are cellular organelles that play a pivotal role in the cell homeostasis through their involvement in degradation and recycling processes of extracellular material that has been internalized by endocytosis and intracellular components that have been sequestered by autophagy (1). Lysosomes may also fuse with t... |
A malignant peripheral nerve sheath tumor (mpnst) is a sarcoma that arises from peripheral nerves or cells of the associated nerve sheath (schwann cells, perineural cells, fibroblasts). The term " mpnst " has substituted previously used terms such as malignant schwannoma, neurofibrosarcoma, and neurogenic sarcoma1,2). ... |
Osteoid osteoma is a benign bone tumor consisting of an osteoid nidus in a highly vascular connective tissue stroma . These tumors are exquisitely painful, and demonstrate characteristic findings on clinical and radiographic examinations . The major drawback of this traditional approach is prolonged surgery and hospita... |
Mouse dis3l2 was expressed in sf9 cells as an n - terminal strep - sumo - tev fusion protein from the pfl vector of the multibac baculovirus expression system . Sf9 cells were infected with baculovirus in hyclone ccm3 media (thermo scientific) at 27c . Following 60 hours of expression the cells were centrifuged at 1200... |
The knowledge about the role of cytokines in psoriasis has developed in the last several years . Initially, only th1 cells and cytokines secreted by these cells, like tnf-, ifn-, and il-2, have been associated with the development and maintenance of chronic inflammatory diseases, such as psoriasis . Th1 cells different... |
Chlamydia genital infection is the most common bacterial infection sexually transmitted in the world (1). The highest age - specific rate was reported in females aged 15 - 35 years . The majority of the females are asymptomatic (2), thus, providing a continuous reservoir for the infection (3). It is estimated that 5 - ... |
Rabies diagnosis is based on fluorescent antibody testing (fat) in brain smears and inoculation of brain suspension either in mouse neuroblastoma cell cultures or intracerebrally in mice as confirmatory assays with high sensitivity and specificity for postmortem diagnosis [13]. These techniques are well suited for rapi... |
Poly implant prothse (pip) company is known to manufacture breast implants using unapproved industrial grade silicone and their products have been banned after numerous studies reporting an increased risk of complications such as implant rupture and gel leakage. [14] over 400,000 pip implants have been utilized for bre... |
Invasive meningococcal disease (imd) is due to infection with the gram - negative bacterium neisseria meningitidis (n. meningitidis). Although fulminant septicemia is less common, it is highly fatal, even if treated . Approximately 500 000 cases occur worldwide annually, resulting in approximately 50 000 deaths and sev... |
Correct estimation of protein concentration in aqueous biological samples is an essential step in biochemical research and the pharmaceutical industry impacting downstream applications ranging from biomarker studies to quality control in the production of biotherapeutics . Determination of protein concentration in most... |
The northern house mosquito, culex pipiens l. (diptera: culicidae), is a member of a species complex that includes vectors of lymphatic filariasis and several arboviral diseases, such as st . Louis encephalitis (sle), rift valley fever (rfv), and west nile virus (wnv). In the northeastern quadrant of the united states,... |
Two male patients with type 2 diabetes (t2d) and coronary heart disease had plasma levels of brain natriuretic peptide (bnp) and n - terminal probrain natriuretic peptide (nt - probnp) measured as part of routine evaluation . Their glomerular filtration rate was normal (> 75 ml / min per 1.73 m), hba1c was <7% with met... |
Isovaleric acidemia (iva) is an inherited autosomal recessive metabolic disease caused by a defect in the metabolism of amino acid leucine . The disease may present as metabolically severe form in the initial 2 weeks of life with acute onset vomiting and lethargy, progressing to coma . The other manifestation may be a ... |
Dr . Coyne - beasley receives research funding from merck & co. none of these funds were used in the conduction or completion of the research contained in this manuscript . This article was supported by grants from the national institutes of health 1r01ai113305 - 01 (cates pi), and by the north carolina translational a... |
In 1994, waldinger et al . Introduced the intravaginal ejaculation latency time (ielt) as a measure for the ejaculation time of heterosexual intercourse . The ielt is defined as the time from the moment of vaginal penetration until the moment of intravaginal ejaculation . In case of ejaculation outside the vagina the m... |
Opces is a bioequivalent, randomized, double blind, multi - centric clinical trial enrolling six centers in five cities of iran . From march 2007 to november 2009, 442 patients were included in this study . Those centers that have the facility and requirements for stenting and also the tendency for research collaborati... |
Animals and treatment: all procedures in this experiment were conducted following protocols approved by the iwate university laboratory animal care and use committee . Four primiparous non - lactating, rumen - cannulated healthy holstein cattle, weighing 645 62 (mean sd) kg, were housed in a stanchion barn at the cattl... |
The importance of early and intensive control of blood glucose levels in improving outcomes for people with type 2 diabetes mellitus (t2 dm) was established in the uk prospective diabetes study (ukpds). Despite differences in glucose levels between the intensive and standard treatment groups disappearing soon after com... |
Calcium channels have not been identified previously in c. albicans, but high - affinity and low - affinity calcium - uptake systems (hacs and lacs) have been described and partially characterized in s. cerevisiae [8, 9]. We identified and deleted in c albicans, homologs of components of these systems the voltage - gat... |
Periodontitis causes loss of tooth supporting bone . The bone loss may be vertical, horizontal, or combined . Regenerative periodontal therapy aims to predictably restore the structure and function of these lost tissues . For this purpose, these grafting materials are available in different forms . Among the graft mate... |
Tuberculosis remains a frequent and important infectious disease worldwide, it occurs with, in approximately 30% of all cases, extrapulmonary involvement in the form of tuberculous pleurisy (tp). And tp increases the morbidity and mortality associated with tuberculosis, and it is a major economic and health burden all ... |
Specific learning disabilities (slds) are a generic term that refers to a heterogeneous group of neurobehavioral disorders manifested by significant unexpected, specific, and persistent difficulties in the acquisition and use of efficient reading (dyslexia), writing (dysgraphia), or mathematical (dyscalculia) abilities... |
Hypoxaemia in critical illness may be caused by hypo - ventilation, ventilation / perfusion mismatch, right - to - left shunting or limitation of diffusion across the alveolar capillary membrane . Hypoxaemia my also occur as a result of breathing a low fractional inspired oxygen tension; for example, at high altitude .... |
Increasing prevalence of morbid obesity has augmented the demand for bariatric surgery, which is so far the most effective and durable therapy for the treatment of morbidly obese patients . Deep vein thrombosis (dvt) and pulmonary embolism (pe) are the major risk factors of mortality after bariatric surgery [24]; venou... |
Urinary tract infections (utis) affect millions of women each year, with an annual societal cost of billions of dollars . Importantly, more than one quarter of women with a uti will have a recurrent infection within six months . There are few established options for prevention of uti other than the use of prophylactic ... |
Retinoblastoma is the most frequent childhood intraocular tumour with an approximately incidence of one in 15,00020,000 births in the world . In africa management of retinoblastoma has been changing during years with a survival rate of more than 95% in developed countries [5, 6]. However, in developing countries these ... |
Temporary external ventricular drainage for refractory thoracolumbar cerebrospinal fluid (csf) leak is not reported in the literature . We present a young man who had multiple complex spinal surgeries for resection of innumerable metastatic ependymoma lesions . As a last resort, we decided to place an external ventricu... |
Ankylosing spondylitis (as) is a chronic inflammatory rheumatic disease that affects the axial skeleton, causing characteristics inflammatory back pain, which can lead to structural and functional impairments . Asymmetric peripheral arthritis is present in about 2040% of patients with as . In europe, estimates of preva... |
An unprecedented outbreak of ebola virus disease (evd) is occurring in west africa . In addition to the morbidity and mortality effects on the population at large, there is a significant impact on healthcare providers in the region . Although many healthcare worker exposures may occur prior to evd being suspected and a... |
Restoration of structure and function using autologous free fat grafts has always been a challenge . The advent and refinement of liposuction and lipoinjection techniques, abundant donor - tissue availability, and relative ease of harvesting have made autologous fat an attractive material for use as soft - tissue fille... |
Turner syndrome (ts) is caused by partial or complete monosomy of the x chromosome . Only a few cases of ts with ischemic stroke have been reported [2, 3, 4, 5]. In previously reported cases, various arteriopathies affecting the cerebral arteries such as fibromuscular dysplasia, hypoplasia, moyamoya syndrome, and, we r... |
Mating is random when two individuals in a population are just as likely as any other two individuals to mate . Nonrandom mating results when individuals tend to choose mates with a specific phenotype and the associated genotype(s) among compatible mates . Dynamics of nonrandom mating have been studied in sexually dimo... |
Stroke, with a high prevalence and long - term disabilities, is a major health problem in the world1, 2, and it was reported that about two million people suffer from stroke each year3 . Impairments including loss of strength, sensation, and coordination abilities, which result in walking difficulties, balance disorder... |
A 3-year - old male, neutered, domestic shorthair cat with a history of chronic regurgitation since being obtained as a kitten was presented for weight loss and regurgitation of all ingested food . The cat was in poor body condition and had a firm swelling in the ventral neck at the time of presentation . Thoracic radi... |
We wish to report some corrections to our study, none of which alters the interpretation of the data or the conclusions drawn . After publication, we noticed that one of the micro - array hybridizations (on sample nb11) was performed on the same patient's material as another hybridization (sample nb4; see table 1; a co... |
The ultrasound (us) appearance of testicular microlithiasis (tm) was first described by doherty et al . In 1987 . The prevalence of tm in symptomatic korean men was found to be 6.0% with significant co - occurrence of tm, testicular cancer, and infertility by yee et al . Although the cause - and - effect relationships ... |
Bluetongue viruses, pathogenic only to domestic cattle and wild ruminants (barratt - boyes and maclachlan, 1995; tsuboi and imada, 1997), are non - pathogenic to humans (xiao et al ., 2004; hu et al ., 2008) and thus, humans do not have pre - existing antibodies to btvs (jeggo et al ., 1983; barratt - boyes and maclach... |
In the last few years, improvements in the endourological armamentarium together with the downsizing of flexible ureteroscopes, the advent of digital technology, and the increasing number of requests for minimally invasive procedures have made the use of flexible ureteroscopy (furs) for renal calculi increasingly attra... |
A 35-year - old male farm - worker presented to the emergency room with alleged history of horse bite to the right forearm about 2 hours prior to presentation while feeding the horse . There was deformity of the forearm with multiple puncture wounds, deep abrasions and small lacerations on the distal - third of the for... |
Other exclusion criteria were history or clinical evidence of coronary or valvular heart disease, congestive heart failure, hyperlipidemia, peripheral vascular disease, chronic gastrointestinal diseases associated with malabsorption, chronic pancreatitis, history of any malignant disease, history of alcohol or drug abu... |
Malignant salivary gland neoplasms account for <0.5% of all malignancies and approximately 35% of all head and neck cancers . Progress in understanding the cell biology of salivary gland carcinomas (sgcs) and detecting vulnerable molecular pathways may lead to the development of new targeted therapy options in these ra... |
Wiskott aldrich syndrome (was) is a monogenic x - linked primary immunodeficiency characterized by the classic triad of microthrombocytopenia, eczema and recurrent infections . Multiple autoimmune manifestations and tumors are serious complications and the life expectancy of was patients is severely reduced, unless the... |
The direct nucleophilic substitution of alcohols is of high interest as it provides access to a wide variety of derivatives, with the formation of water as the only by - product . Indeed, the acs green chemistry institute pharmaceutical roundtable identified oh activation for nucleophilic substitutions as a priority ar... |
Notch proteins are evolutionarily conserved cell - surface receptors for transmembrane ligands of the dsl family (named after the delta and serrate ligands of drosophila). Signaling by notch regulates a broad range of cell - fate decisions during development and various human diseases, including cancers, the extracellu... |
Choriocarcinoma is one of the malignant tumors arising from trophoblastic cells characterized by the secretion of human chorionic gonadotrophin (hcg). The tumor consisted of two basic cell types: cytotrophoblast and hcg - positive syncytiotrophoblast, the typical histologic features of choriocarcinoma (1 - 5). The seru... |
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