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A 19-year old female presented to our dermatological clinic with hyperpigmented, indurated and atrophic patches on a zosteri - form distribution extending from her left sub - mammary region (figure 1) through to her back (figure 2). The patient denied any personal or family past medical history of interest, except for ... |
Traumatic brain injury (tbi) is a significant cause of emergency room visits, hospital stays, and morbidity and mortality in the usa.1 the leading causes of tbi are falls, motor vehicle accidents, struck by / against events including collision and contact sports, and assaults, with three peak mean ages of 04 years, 151... |
The chronic inflammatory airway disease, asthma, and chronic obstructive pulmonary disease (copd) are significant causes of morbidity and mortality in children and adults . Asthma affects over 300 million people worldwide, and the prevalence is increasing among all demographics . These diseases are hallmarked by a th2-... |
The landmark study gog 33 described the patterns of spread in endometrial carcinoma and concluded that clinical staging is inaccurate as 22% of clinical stage i patients were assigned a higher surgical stage . As such, the international federation of gynecology and obstetrics (figo) changed the endometrial cancer stagi... |
Inflammation can be understood as the defense reaction of host against injury, which varies depending on the particular agent, tissue, and individual host characteristics [14]. Accordingly, infectious disease has been regarded as an inflammatory response caused by a microorganism that acts as an injury agent . Histopat... |
Strain bs062 showing antagonistic effects against b. cinerea was isolated from a soil sample collected at mt . Strain bs062 was identified as belonging to genus streptomyces on the basis of its structural and morphological characteristics (data not shown), and thus strain bs062 was designated as streptomyces sp . 16s r... |
We employed a synthetic small - area estimation approach that combined indirect standardization of nhanes data with regression - based estimates of state - level hcv - related mortality . The data sources and approach are described below and in table 1 and figure 1 . Data sources and purposes for primary and sensitivit... |
Each year there are an estimated 15,780 children (age less than 19 years) who are diagnosed with cancer in the united states and approximately 250,000 children worldwide . While use of chemotherapy and radiation approaches has resulted in improved cure rates, cancer remains the most common cause of disease - related mo... |
Usually, the pmi is estimated by assessing the postmortem morphological changes that include algor mortis, rigor mortis, livor mortis, postmortem clotting, putrefaction, and adipocere formation . Although there are various methods adopted to estimate the pmi, newer methods are being investigated as an additional aid so... |
In the present day of globalization and liberalization, legal profession which serves as center of the sociopolitical domain of the indian society, is growing very fast . India is the biggest democracy of the world where judiciaries enjoy one of the most powerful and independent status . In the present scenario, the le... |
A 12 year old boy, who was status post repair (shortly after birth) of tetralogy of fallot with pulmonary atresia and subsequent replacements of right ventricle to pulmonary artery conduit 4 years prior to current evaluation, was seen in an outside pediatric cardiology clinic for his annual follow - up appointment . Th... |
Metallic nanostructures composed of more than one component have attracted attention because of their vast potential for multifunctionality . In the best cases, such architectures provide function beyond the sum of their parts, enabling useful or unique combinations such as plasmon - enhanced catalysis, magnetically ad... |
A 74-year - old woman presented to the pain clinic with a history of chronic left sided sciatic pain that also restricted her mobility . She had been treated with nonsteroidal antiinflammatory drugs, pregabalin, tramadol, and acetaminophen without much relief . In addition this slim pleasant lady had limited left leg r... |
We conducted the present meta - analysis in accordance with the guidelines of the meta - analysis of observation studies in epidemiology group (19). A systematic literature search was performed to identify all studies published before 10 february 2012 that investigated the association between inflammatory markers and t... |
Parathyroid carcinoma is a rare disorder, accounting for 0.1% to 5.0% of all cases of primary hyperparathyroidism [15]. The disease presents at a mean age of 50 years and is equally likely to occur in males as in females [26] (table 1). Clinical and biochemical manifestations are those of severe primary hyperparathyroi... |
Total laparoscopic hysterectomy has been shown to be a safe method of hysterectomy with minimal complications, yet only 12% of hysterectomies are performed by this route, with 22% by vaginal approach and 66% still being performed by laparotomy . Surgeons have been encouraged to employ vaginal and laparoscopic routes fo... |
The places in therapy for the three new drug principles recently approved for treatment of lower urinary tract symptoms / overactive bladder (luts / oab), the 3-adrenoceptor (ar) agonist, mirabegron, the phosphodiesterase 5-inhibitor tadalafil, and the blocker of afferent and efferent neutotransmission, botulinum toxin... |
Patients diagnosed with invasive bladder cancer (bc) in denmark are treated according to the national guidelines at one of the five uro - oncological centers . The aim of the danish bladder cancer database (dablaca - data) is to monitor treatment and general survival of patients diagnosed with bc in denmark . The goal ... |
Detailed protocols, all sequences and their optimization, and full characterization of all synthesized reagents are provided in the supplementary material . Briefly: oligonucleotides were coupled to antibodies, unless stated otherwise, in a two - step procedure: (i) dtt was used under conditions that reduce interchain ... |
Success is measured by the extent to which the community of scientists can successfully tackle hard problems . As the diversity of the group of problem solvers increases, so too does the group s ability to find innovative solutions to difficult and complex problems (page, 2007; jackson and joshi, 2011; kets and sandron... |
Replication forks pause at specific sites under unperturbed conditions (deshpande and newlon, 1996). Fork stalling occurs in response to intra - s dna damage or dna synthesis inhibition . Hydroxyurea (hu) causes deoxi - nucleotides triphosphate (dntps) deprivation (krakoff et al ., 1968), fork stalling, and activation ... |
Endodontic therapy requires a thorough knowledge of root canal morphology to adequately shape and clean the canal system . Proper care and attention should be directed in identifying and negotiating extra roots and canals . In a radiographic study of extracted teeth goel et al reported mandibular first molars had 3 mes... |
The word metabolism comes from greek metabol which means change or transformation, and in fact the levels of most cellular metabolites change with half times of minutes, seconds, or even faster . During the past years the complexity and dynamics nature of the metabolites have become increasingly apparent [16]. The comp... |
Inactive genes in mammals often have particular features which differentiate them from their active neighbours . High levels of dna methylation have been found to be associated with a large number of inactive endogenous genes in normal tissues and also with many genes which are aberrantly silenced in tumour cells . Dna... |
Peritoneal dialysis (pd) catheter rupture is rare, but can occur traumatically or spontaneously . When the rupture occurs close or proximal to the exit site however, this requires an interruption in pd and subsequent hemodialysis (hd) catheter insertion for temporary transfer to hd . Therefore, partial replantation of ... |
The most common treatment for hydrocephalus is insertion of a ventriculoperitoneal (vp) shunt . A vp shunt is associated with several well - recognized complications, including infection, hemorrhage, neural trauma, shunt malfunction, and blockage . One of the complications that causes a shunt system malfunction is migr... |
A 43-year - old woman described a three - year history of progressive left upper lid swelling and ptosis . Her primary ophthalmologist treated her for a presumed chalazion with warm compresses and various ointments . She denied loss of visual acuity, but noted progressive diplopia with eccentric gaze over the last seve... |
Crohn's disease is a chronic intestinal disorder of unknown etiology characterized by weight loss, abdominal pain, diarrhea, arthritis and the development of fistulae and abscesses . It causes significant morbidity and affects approximately 1 in 1000 individuals in the developed world . Crohn's disease is believed to e... |
Having a family history of breast cancer has been established as one of the most important risk factors for the development of breast cancer [13]. A reduction in breast cancer mortality attributable to mammography among women aged 50 to 74 has been demonstrated [46]. In canada, average - risk women aged 50 to 74 are re... |
Full - thickness wounds often need complex procedures for defect closures, in particular when bone, cartilage or tendons are exposed . In recent years, the spectrum of flaps and grafts has been expanded by dermal templates and tissue engineering . Matriderm (dr . Suwelack skin and healthcare ltd ., billerbeck, germany)... |
Frontotemporal lobar degeneration (ftld) is a common cause of early onset dementia (rabinovici and miller, 2010). Its prevalence and incidence is similar to alzheimer's disease in individuals under the age of 65 years . Behavioral variant frontotemporal dementia (bvftd), its most common subtype, is characterized by dee... |
Hypertrophic olivary degeneration (hod) is a rare phenomenon in the dento - rubro - olivary pathway that was first described by oppenheim in 1887 (1, 2). Hod is a unique form of transneuronal degeneration in which the inferior olivary nucleus undergoes hypertrophy followed by atrophy, as a consequence of lesions to the... |
Impaired insulin secretion and insulin resistance both contribute to the pathogenesis of type 2 diabetes mellitus (t2 dm). Different oral antidiabetic drugs are used to treat t2 dm depending on the pathogenesis in individual patients . For example, -glucosidase inhibitors are used to treat postprandial hyperglycemia, b... |
Women who have a history of tubal ligation and desire a return to fertility have the options of tubal anastomosis (ta) or in vitro fertilization (ivf). Ta has been found to be cost - effective for all women of reproductive age including those over 40 years of age . For appropriate candidates who have proceeded with ta,... |
Melanomas are tumors arising from melanocytes, which are derived from neuroectoderm located in the basal layers of skin, skin annexes, and more rarely in the mucosal membrane . Common sites for melanomas are head, neck and the lower extremities, less common sites being the oral mucosa, nail beds, conjunctiva, orbit, es... |
Inguinal herniorrhaphy remains one of the most common general surgical operations, with approximately 15% performed for recurrence and there is little available evidence on the optimal management of recurrent inguinal hernia . The repair of the resulting recurrent hernia is a daunting task because of already weakened t... |
The participants with type 2 diabetes were recruited from patients who regularly visited the outpatient clinic of the department of medicine, shiga university of medical science, between 1997 and 1999 . Type 2 diabetes in these patients had been diagnosed in accordance with the criteria of the world health organization... |
Adolescents constitute only a small percentage of treatment seekers in drug dependence treatment settings (15 years: 0.4% and 16 - 20 years: 4.6%). Community surveys suggest that tobacco, alcohol and cannabis are prevalent substances of abuse among indian adolescents, but opioid use is quite uncommon in this age group ... |
Mycosis fungoides (mf) is a non - hodgkin's lymphoma of t - cell origin, primarily involving the skin . It is a relatively rare disease with an annual incidence of 0.36 per 100,000 . In advanced cases, it may affect extracutaneous regions such as lymph - nodes, viscera, peripheral blood and skeletal sites . Accurate de... |
Sensitivity to house dust was confirmed in the 1920s by studies showing positive skin prick tests to house dust in many asthmatic individuals . Such studies sparked scientific interest into what specific component of house dust was responsible for the sensitisation but it was not until the 1960s that voorhorst and coll... |
Flat foot is a condition in which the medial longitudinal arch of a foot is chronically and abnormally collapsed1 . Flat foot is caused by the pathologic malalignment of the lower extremity (le) joints2, abnormal muscle activity3, cartilage damage, and/or knee pain4 . It should be appropriately managed because it may l... |
Posterior pedicle screw fixation of the thoracic and lumbar spine provides rigid stabilization, however, inserting thoracic pedicle screws is technically demanding, with high rates of inaccurate placement, which can lead to pedicle fractures and construct failure . In a study on the multidirectional flexibility of pedi... |
The description of atomic structure by niels bohr set the basis for the emergence of quantum physics . According to his theory, atoms existed in a state of inertia, in which they did not radiate any energy . However, in - between excitement and rest, they would be able to radiate energy (or quanta).1 based on these fun... |
Schimke immuno - osseous dysplasia (siod) is a fatal syndrome inherited as an autosomal recessive trait, and manifests with facial dysmorphism, growth failure, nephropathy, recurrent infections, hypothyroidism, episodic lymphopenia, and neurologic symptoms . Biallelic loss of function mutations of swi / snf2- related, ... |
Allergic diseases are among the most common disorders in children, and ocular allergy represents one of the most common ocular conditions encountered in clinical practice . The prevalence of allergic diseases in children aged 6 to 14 years varies significantly from 0.3% to 20.5%, and is gradually increasing.1 this incr... |
Atrial fibrillation (af) is the most common sustained arrhythmia in western countries, with an estimated 30 million patients affected by 2050 across united states and europe alone . Atrial fibrillation has a significant impact on morbidity mainly related to symptoms, heart failure, and thromboembolic events and is the ... |
Growth is a volumetric and longitudinal development and is essential to take into account when treating children with a wide variety of disorders . In particular, during the treatment of patients with adolescent idiopathic scoliosis (ais), it is important to understand the growth and future growth of the patient . The ... |
With the introduction of newer drugs to treat various skeletal disorders, the adverse effects of these drugs are also challenging to deal with . They are synthetic analogous of pyrophosphate, a natural regulator of bone metabolism found in bone matrix . They inhibit the differentiation of osteoclastic precursors, induc... |
Cleft lip and palate is a congenital anomaly produced by embryological defects during formation of the face . A child is born with a cleft somewhere in the world every 2 min according to a world health organization study published in 2001 . In india, the number of infants born every year with the cleft lip and palate i... |
All procedures were conducted with the approval of the animal research committee at our institution . Each dog was sedated with an intramuscular injection of 4 mg / kg xylazine hydrochloride (rompun, bayer korea, seoul, korea) and 10 mg / kg ketamine hydrochloride (ketara, yuhan yanghang, seoul, korea) for the procedur... |
Barrett esophagus (be) is defined as a change in the distal esophageal epithelium of any length characterized by columnar type mucosa during endoscopy and is confirmed to have intestinal metaplasia by biopsy.1,2 be is considered a complication of chronic gastroesophageal reflux disease (gerd)3 and has the potential to ... |
Acute ischemic stroke by occlusion of internal carotid artery (ica) is known to have relatively high rate of ischemic progression and recurrence . However, ica occlusion can have variable clinical courses from no symptom to severe neurologic deficit according to the degree of collateral flow . Thus, the assessment of c... |
In 2003, a dutch committee developed evidence - based guidelines for the treatment of inguinal hernia (ih) in children and adults . The guidelines for adults are mainly based on systematic reviews of randomised controlled trials (rcts) with consistent results from individual (homogenous) studies, thus, creating level 1... |
Using scanning electron microscopic and light microscopic techniques, adriaens et al1 demonstrated bacteria invading the radicular cementum and the dentinal tubules of the radicular dentin of periodontally diseased, caries - free human teeth . It has been reported that periodontal diseases, periodontal treatment, such ... |
Parkinson's disease (pd) is a fatal and incurable neurodegenerative disorder characterized by resting tremors, postural instability, and bradykinesia . The death of midbrain substantia nigra neurons characterizes the pathology of both familial and sporadic forms of pd . Two types of molecules accumulate within these dy... |
Oral cancer accounts for 12.5% of overall cancers in india contributing significantly to the challenges faced by oncosurgeons and plastic surgeons . Based on the complexity, the reconstruction of buccal mucosa defect has been done with direct closure, skin grafting or various flaps, such as the pectoralis major myocuta... |
Esthetics has become a demand even during orthodontic treatment, particularly in adult patients, who do not like accessories that call people's attention . In a recent study with 27-year - old individuals in sweden, 67% of the interviewees would wear metal brackets if needed, which means that one third of young adults ... |
Motions like reaching are influenced by lesions affecting the sensorimotor system, and an understanding of the influence of such lesions on movement control and physical motion compensation is therefore essential for rapid rehabilitation1 . Altered upper - limb function in patients with brain damage can make it difficu... |
Anogenital involvement is most common in lsa in both the sexes.blister formation in the lesion of lsa occurs due to basal cell degeneration resulting in dermal - epidermal separation and marked edema in upper dermis . Blister formation in the lesion of lsa occurs due to basal cell degeneration resulting in dermal - epi... |
In both the uk and the us, medical education, including assessment, has been transformed over the last 30 years, driven by changes to the medical environment in which graduates will work . There has been a shift away from the traditional apprenticeship model of learning in medicine: the student is no longer considered ... |
Transcranial magnetic stimulation (tms) is a noninvasive method of stimulating cortical neurons; that is, electrical currents in axons of interneurons stimulated by tms activate cortical neuron cell bodies via synaptic transmission . Single tms or repetitive tms (rtms) can transiently inhibit or facilitate cortical neu... |
Similarly, in germany, approximately 10.9% of the population is involved in accidents annually, and trauma is the second commonest cause of hospitalization . Trauma registries have been established globally in an effort to improve the management and outcome of trauma patients . In 1991, the scottish trauma and audit gr... |
There is accumulating evidence that cancer of the ascending and transverse (right side) colon is different from cancer of the descending and sigmoid (left side) colon . These two segments of the colon have differences in anatomy, embryology, physiology, epidemiology, and gene expression . Right- and left - side colon c... |
The most common causes of lower limb ulcers include ischaemic ulcers, diabetic / neuropathic ulcers, and venous ulcers . Martorell ulcer is a rare ischaemic ulcer that is specifically associated with longstanding, poorly controlled hypertension . Typically, the patient presents with extreme pain out of proportion to th... |
This report depicts the feasibility of the concomitant repair of a large direct inguinal hernia with mesh by using the intraperitoneal onlay approach after extra - peritoneal laparoscopic radical prostatectomy . A 66-year - old man with localized adenocarcinoma of the prostate was referred for laparoscopic radical pros... |
Helicobacter pylori (h. pylori) infection is one of the most common bacterial infections in human and has been associated with several gasterointestinal diseases including gastric ulcer, duodenal ulcer, gasteric cancer and gastric mucosa associated lymphoid tissue (malt) lymphoma (1, 2). The prevalence of h. pylori inf... |
Madin darby canine kidney (mdck) cells, stably transfected with the cdna encoding pigr derived from rabbit (obtained from keith mostov, university of california, san francisco), were maintained in mem containing 10% fetal bovine serum (hyclone, logan, ut), 100 m nonessential amino acids, 2 mm glutamine, 20 g / ml genta... |
Liposomes are nearly spherical, microparticulate, multilamellar or unilamellar bilayer vesicles made from lipids alternating with aqueous sections . They also bear resemblance to micelles, although there are some key differences between them (figure 1). They were first discovered by dr alec d. bangham in 1961 at babrah... |
Chest pain is a common symptom that may be caused by obstructive coronary artery disease (cad) and requires risk stratification to assess the probability of cad . Risk algorithms have been developed based on combinations of risk factors [2, 3]. However, these models tend to overestimate the prevalence of cad, and are b... |
The performance of definitive cements and the longevity of a restoration are affected by preparation coarseness, and the type of provisional cement, and cleaning technique used to remove provisional cement remnants.1 due to the negative effect that residual provisional cement, and debris on prepared abutment teeth may ... |
Reoperation in strabismus surgery is not uncommon for patients with under- or overcorrection of an ocular deviation [1, 2]. In cases of recurrent exotropia after primary lateral rectus (lr) muscle recession surgery; there remains a choice of conservative treatment or reoperation, depending on the severity of deviation ... |
Avaliar o bloqueio da metaloproteinase da matriz (mmp)-2 e da mmp-9 e a variao do vef1 em pacientes com linfangioleiomiomatose (lam) aps o uso de doxiciclina, um conhecido inibidor de mmp, durante 12 meses . Ensaio clnico aberto de brao nico no qual as pacientes com diagnstico de lam receberam doxiciclina (100 mg / dia... |
Any non - fatal and deliberate self - injury in which a person intentionally and without interference from others puts him / herself at risk of death is referred to as a suicide attempt (1). Worldwide, the number of suicide attempts resulting in death for adolescents is higher than for other age groups (2, 3). In some ... |
Primary intestinal lymphangiectasia (pil) is a rare disorder of the intestine that is part of exudative gastroenteropathies and has primarily been described in children by waldmann et al . Reports in adulthood are even more rare [13]. Diagnosis of pil is quite difficult for gastroenterologists because the symptoms vary... |
Bacterial growth has been intensively studied during the last century, and the understanding of bacterial cultures has increased from decade to decade . However, the intrinsic variability and heterogeneity of bacterial axenic cultures (vives - rego et al ., juli and vives - rego), as well as the complexity of the diffe... |
Chronic liver disease and cirrhosis are important causes of morbidity and mortality in the world . Moreover, the burden of chronic liver disease is projected to increase due in part to the increasing prevalence of end - stage liver disease and hcc secondary to nafld and hcv . Liver transplantation is the best treatment... |
All reagents and solvents were obtained from commercial suppliers and were used without further purification, unless otherwise stated . Nmr spectra (h and c) were recorded on a bruker avance iii 400 mhz spectrometer . Chemical shift values are expressed in parts per million (ppm).for shorter reaction times (25 min), th... |
Innate immune cells include both myeloid cells, such as neutrophils and circulating monocytes which differentiate into macrophages within tissues, and innate lymphoid cells (ilcs). These cells have important functions in host defense, including the phagocytosis of pathogens, the release of antimicrobial proteases, and ... |
There were 3 women and one man, and the mean age of diagnosis was 49.5 years . Two patients were asymptomatic, and one, who had smoked for 10 pack - years, complained of cough . A 56-year - old woman had manifested the symptoms of mg, such as ptosis, dysarthria and difficulty in swallowing, and the serum level of anti ... |
C1q nephropathy is a proliferative glomerulopathy characterized by extensive c1q mesangial deposition in the clinical setting of steroid - resistant proteinuria (1). So far, its etiology is not well - known, and the case reports associated with infection have been rare . Epstein - barr virus (ebv) is a ubiquitous human... |
Papilloma virus (pv) was first established as a carcinogenic virus by rous and beard (1934) in cotton rabbit . Human papilloma virus (hpv) was identified from the cervical smears by meisels and fortins (1976). Syrjanen k (1983) demonstrated the presence of hpv in oral cancer tissue by immunohistochemical markers . Hpv ... |
Evidence that organization of cardiovascular care may be effective in reduction of morbidity and mortality has existed since at least the 1950s when cardiologists implemented specialized care in coronary units for patients with acute heart disease.1 we learned in chemistry class of the laws that govern free energy that... |
Peanut - allergic (pa), peanut - sensitized but tolerant (ps), and non peanut - sensitized nonallergic (na) children were prospectively and consecutively enrolled from our pediatric allergy service on the days when the investigator (a.f.s .) Was available to perform bat . The allergic status to peanut was determined by... |
After satisfaction of all the required conditions, authorities of three primary schools agreed for participation . Necessary approval was obtained from vidyasagar university and school authorities prior to the commencement of the study . All students of those schools were invited to participate in the survey and the re... |
We identified outbreak source cases through a review of investigation reports of tb outbreaks written by centers for disease control and prevention (cdc) staff during 20022011 . In a previous publication, we described how cdc teams that assist public health partners with tb outbreaks write standardized reports about fi... |
Two patients presented with clinically diagnosed oca (diffuse skin and hair hypopigmentation, diffuse iris transillumination, foveal and optic nerve dysplasia and fundus hypopigmentation [figs . 1 and 2]) and exotropia 40. they both had mild horizontal jerk nystagmus without abnormal head posture, and neither had a his... |
The most common site is in the infrascapular region beneath the muscular tissue . In magnetic resonance imaging (mri), a preferable noninvasive investigation, elastofibromas typically appear as a solitary, poorly circumscribed, heterogeneous, soft - tissue mass . In the absence of a reliable preoperative diagnostic inv... |
Dyskeratosis congenita (dc) is a rare inherited disorder characterized by premature aging, bone marrow failure and predisposition to malignancies . In its classical form, there is skin pigmentation, nail dystrophy and mucous membrane leukoplakia . The major form of dc is x - linked and, therefore, there is an abundance... |
Cardiovascular disease (cvd) remains the number one cause of death in the united states . A number of risk factors for coronary heart disease (chd) and stroke have been identified, and population - based studies have begun to examine cvd risk prospectively in african americans . Recent literature has established that d... |
The gastric ulcer is defined as a disturbance of the integrity of the gastric mucosa that causes a local defect or excavation due to active inflammation . Nowadays, aggressive and defensive factors are widely known to play a role in the development of a gastric ulcer . The aggressive factors are gastric acid, pepsin, b... |
. Early markers of the syndrome are often present before persistent blood pressure elevation . Progression is strongly associated with functional and structural abnormalities that damage the heart, kidneys, brain, and vasculature . Based on population - based survey conducted in 1979 arterial hypertension comprises 12%... |
Since the earliest studies on glial cells in the 19th century, ramn y cajal, camillo golgi, and their contemporary colleagues have described astrocytes as very particular cells in intimate contact with neurons and capillaries . Based on these observations, they made different hypotheses on their physiological function,... |
Students of ballet schools learn the art of dance for years by exploiting their locomotor system, which is subjected to high loads of physical effort . Breaking the limit of the motor system adaptative skills contributes to the occurrence of motor system dysfunctions, leading to injury . The most common injuries experi... |
The association between fetal chromosomal abnormality and increased nuchal translucency (nt) thickness during the first trimester of pregnancy is well - established (1, 2). Such a screening test may identify over 70% of trisomy 21 pregnancies in the first trimester, with a 5% screen - positive rate (1, 2). Even in a ch... |
Periprosthetic infection after tha is a catastrophic complication which presents an enormous challenge to the orthopaedic community . Diagnosis is often difficult as no gold standard test is available; thus, the diagnosis relies on the surgeon's judgement of the clinical presentation, the findings on physical examinati... |
Adenomyosis is a benign condition characterized by myometrial spreading of the endometrium, usually involving the basal layer . Clinically, the disease may cause severe, secondary dysmenorrhea associated with menorrhagia and chronic pelvic pain . Adenomyosis commonly appears within the myometrium as clusters of small c... |
The growth and disassembly of actin filaments allows cells to perform important functions such as motility and division . The typical pathway for actin filament growth is as follows: atp - bound monomeric actin (g - actin) adds at the barbed end of the actin filament (f - actin), atp is hydrolyzed in the filament, and ... |
Acute basilar artery occlusion (bao) is a rare cause of stroke with a high mortality rate and an often poor clinical outcome among survivors . Randomized trials have shown the safety and efficacy of intra - arterial fibrinolysis (iaf) given within 6 hours . Based on these trials, iaf has been used in clinical practice ... |
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