text stringlengths 0 868k |
|---|
Diabetes mellitus (dm) has emerged as one of the major global health problems and a heavy burden for all healthcare systems . Current predictions estimate that by 2025 more than 480 million people globally will have an altered glucose tolerance and 380 million will have developed type 2 diabetes . Among diabetic compli... |
Pyloric stenosis (ps) is one of the most common surgical conditions affecting infants with an incidence of approximately 0.9%5.1% per 1,000 live births, generally presenting prior to 3 months of life.1,2 since the end of the 19th century, surgical intervention has been the primary treatment with first open and then sub... |
In late august 2003, local, state, and federal health officials began an investigation to determine the risk factors associated with an outbreak of cryptosporidiosis and to develop interventions to control it . The epidemiologic investigation resulted in 96 laboratory - confirmed cases of cryptosporidium infection and>... |
The internal globus pallidus (gpi) and substantia nigra pars reticulata (snr) are the basal ganglia (bg) output nuclei . Besides projecting to the thalamus to form the cortico - bg loops (chevalier et al ., 1985; smith and bolam, 1989; alexander and crutcher, 1990; delong, 1990; smith et al ., 1998; haber, 2003), outpu... |
Though, the advantages of central venous catheter (cvc) placement outweigh the disadvantages significant risks are associated with the insertion and maintenance of a cvc . We report an unusual complication of cvc, discovered during thoracotomy, which possibly goes unnoticed in an unknown number of patients . A 37-year ... |
Vascular endothelial growth factor (vegf) and its receptors are thought to play a pivotal role in tumor angiogenesis . Bevacizumab is a humanized monoclonal antibody designed to block vegf - a and has proved to be effective in colorectal cancer, nonsmall cell lung cancer, renal cell carcinoma, ovarian carcinoma, and gl... |
In a remarkable number of patients suffering from low back pain (lbp), a specific physiological or structural abnormality cannot be found . Although implementation of imaging strategies aids to exclude serious underlying mechanical etiologies of lbp, this complaint in majority of cases might be associated with the infl... |
Achalasia cardia is a primary motility disorder of the esophagus characterized by aperistalsis of the body of the esophagus and failure of relaxation of the lower esophageal sphincter (les) appropriately in response to swallowing.1 it is a chronic, benign disease of unknown etiology and is a common cause of dysphagia .... |
Three - dimensional (3d) computer reconstruction of a target volume or of a surface is an important activity in modern biomedical imaging . The accurate anatomical reconstruction in trauma or for use in image - guided intervention relies on mathematical imaging technology; and this paper develops the mathematical techn... |
In a recent article for critical care link and colleagues reported that the reversible platelet glycoprotein iib / iiia antagonist tirofiban may prevent platelet activation and preserves platelet numbers during continuous venovenous haemodialysis in patients with cardiogenic shock . Acute kidney failure is a frequent c... |
Children and adolescents with gerd usually have a history of vomiting and spitting up as an infant . If gerd is left untreated, it can lead to dysphagia, odynophagia, esophageal stricture, chronic hoarseness, laryngitis or respiratory problems such as coughing or reactive airway disease in children and non - cardiac ch... |
Muscle fatigue involved in inspiration, such as diaphragm muscle, external intercostal muscle, or parasternal intercostal muscle, induces a shortness of breath resulting in impaired exercise tolerance1, 2 . In addition, diminished respiratory muscle strength results in the reduced efficiency of coughing to remove airwa... |
The underwater environment produces some pathophysiological problems due to the fast changing of its bounded pressure which may cause various illnesses that might be difficult to detect and treat . Our nervous system is an organ which is very sensitive to underwater pressure changes, and a damaged nervous system can le... |
It is usually controlled by cis - acting factors, such as au - rich elements (ares) in the 3utr, and transacting factors, such as rna - binding proteins, mirna, and ribonucleases (reviewed in refs . Traditionally, the 3utr has been viewed as the region most recognized by rna - binding proteins such as tristetraprolin (... |
Patients fulfilling criteria for ftd were consecutively recruited from the centre for aging brain and neurodegenerative disorders, university of brescia, italy, from december 2001 to july 2014 . All patients underwent somatic and neurologic evaluation, routine laboratory examination, and a complete mental status evalua... |
Small cell carcinoma is a malignancy that occurs mainly in the lung, and primary lesions in the head and neck are very rare . Extrapulmonary small cell carcinoma (epscc) shows a fair response to either chemotherapy or chemoradiotherapy, similar to small cell lung carcinoma (sclc); however, poor prognosis has been repor... |
Hiv is a preventable chronic, life - threatening illness affecting fetal and maternal health, increasing both morbidity and mortality in both infected and noninfected children worldwide [13]. Given the lack of an effective vaccine and the complexity of life - long treatment, prevention of maternal to child transmission... |
Home care is a rapidly expanding and evolving industry . As levit and her colleagues highlight, home health is the fastest growing component of medicare expenditures . Medicare spending on the home health benefit has grown from $2.12 billion in 1988 to $10.5 billion in 1993 and is projected to exceed $22 billion by the... |
Ovarian cancer is the most lethal gynecologic malignancy among women, with an estimated 150 000 annual deaths worldwide . However, due to the unspecific and inconspicuous symptoms in the early stage of ovarian cancer, there are no effective and accurate detection methods for this disease . Moreover, although the initia... |
Male sd rats (simonsen laboratories, gilroy, ca) were housed individually and maintained on a 12-h light / dark cycle (lights on at 0600 h) with ad libitum access to pelleted rodent food (f6 diet; harlan teklad, madison, wi) and tap water . All experimental procedures were approved by the washington state university in... |
Reports have described the increasing use of endoscopic ultrasound - guided hepaticogastrostomy (eus - hg) to treat malignant biliary obstruction in patients with endoscopic retrograde cholangiopancreatography (ercp) failure . However, a previous review article noted that despite its high success rate, eus - hg is asso... |
Consumer - directed healthcare (cdhc) is center stage in health policy debates . Many politicians and corporate leaders hope that high deductible health insurance policies will cut costs by coaxing people to think twice before visiting the emergency department (ed), drug store, or mri suite . The basic idea is that ame... |
Chronic recurrent multifocal osteomyelitis (crmo), a disorder that primarily affects children and adolescents, is characterized by episodic osseous pain over several years . Crmo is an idiopathic, aseptic, auto - inflammatory disease with no uniformly effective treatment . The long bones of the lower extremities are fr... |
The increasing number of road traffic accidents in our country has made it extremely difficult to analyze the exact reported incidence of mortality and morbidity due to airway and facial trauma . The incidence of maxillofacial trauma and airway involvement as a result of roadside accidents is quite varied and an approx... |
We developed and followed a standardized protocol to do this meta - analysis in accordance with the preferred reporting items for systematic reviews and meta - analyses (prisma) guidelines.28 two investigators (x.l . Independently conducted literature searches of medline, embase, and the cochrane central register of co... |
Exercise physiology and the salutatory effects on weight loss, fat reduction, and insulin sensitivity have been described in great detail . These beneficial effects are now considered to reflect, at least in part, the effect of exercise on the activation of amp - activated protein kinase (ampk). In obese non - diabetic... |
Antigen - activated cd4 t cells differentiate into either th1 or th2 cells, producing proinflammatory or proallergic cytokines, respectively . The best understood mode of regulating th cell differentiation is the cytokine environment during primary t cell activation, with il-12 associated with th1 development and il-4 ... |
In the united states nearly 40,000 deaths are attributed to metastatic breast cancer (mbc) annually . Once breast cancer has metastasized it is usually fatal; however, intensive research into the causes of breast cancer and the development of an array of effective targeted therapeutics has improved survival for these w... |
A 56-year - old man was hospitalized because of pain and numbness in his left hand since he slipped a week earlier ., we found that the motor and sensory functions of his left hand were normal . His laboratory data, including anti nuclear antibody, anti - neutrophil cytoplasmic antibody, and rheumatoid arthritis factor... |
A 17-year - old healthy male was seen with complaints of painless swelling over the left eye for the past four weeks . The rest of the systemic and ocular history was not significant . On examination his vision was 20/20 both eyes . On slit - lamp examination there was erythematous, subconjunctival nodular mass in the ... |
Idiopathic granulomatous mastitis (igm) is an uncommon disease which usually arises in premenopausal women shortly after their last childbirth . Its etiology is unclear, however, breast - feeding and the use of oral contraceptives could exert an influence in its pathogenesis . Very often clinical and radiological findi... |
Scapular spine stress fractures are uncommon following cuff tear arthropathy, there are only six reported cases in the english literature . Management of these fractures remains a challenge because of poor bone quality and persistent deforming force at the fracture site . Management of these fractures can be conservati... |
Pathways of gene silencing and small regulatory rnas such as mirnas (micrornas) and sirnas (short interfering rnas) are widespread in almost all eukaryotic organisms [1, 2]. These pathways are known to act in development, heterochromatin formation, regulation of gene expression at transcription, posttranscription, and ... |
Preparation of hard tissues for the insertion of dental implants is usually performed by drilling at high - speed with irrigation . Recently, a new concept of low - speed drilling (50 rpm) without irrigation was suggested as an alternative to the conventional procedure123 . The low - speed drilling has several advantag... |
A 66-year - old japanese woman was referred to us with a 6-month history of decreased vision and metamorphopsia in the left eye . Visual acuity was 20 / 16 for the right eye and 20 / 32 for the left eye . Fundus examination showed mild epiretinal membrane in the macula of the right eye, and an elevated, oval, 1-disc - ... |
Autophagy is generally considered to be a cell survival mechanism and may also contribute to cell death, depending on its various biological contexts.sphingolipids were first discovered in brain extracts in 1876, and within a century of intensive research, the chemical structures of thousands of individual sphingolipid... |
Periodontitis is a multifactorial chronic inflammatory disease characterized by destruction of tooth - supporting tissues . The progression of periodontal destruction involves complex interaction between periodontal bacteria and cells of immune system . The complex cytokine network that mediates the immune response inc... |
Minimally invasive surgical (mis) total knee arthroplasty (tka) was developed to facilitate early and intermediate - term rehabilitation . Mis generally includes reduced length of skin incision, less invasive arthrotomy, avoidance of tibiofemoral dislocation or hyperflexion, and use of special cutting blocks and retrac... |
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (cadasil) is a systemic arteriopathy due to missense mutations of notch3 gene . Earlyonset ischemic strokes and vascular dementia are the main clinical features . Migraine, psychiatric disorders, and epileptic seizures are additi... |
Although the disease is initially sensitive to adt, resistance is inevitably acquired, leading to castrate - resistant prostate cancer (crpc) which is incurable . However, there are several agents which can improve survival in such patients (see table 1). Antiandrogens are oral compounds that compete with endogenous li... |
More than 50% of individuals with voice disorders have benign alterations of the vocal fold mucosa . Polyps are one of the most frequent vocal cord lesions and are the most prevalent indication for laryngeal microsurgery . Like nodules, polyps are caused by overuse and abuse of the voice1, although they may also occur ... |
Irrigation has been recognized to have been playing a crucial role in addressing the central challenges caused by food insecurity and rainfall uncertainty . It offers more yield assurance than rainfed agriculture and tends to improve the quality and value of crop yields . It is also often the key to successful commerci... |
Amalgam is a restorative material especially suitable for classes i and ii restorations in teeth that encounter heavy chewing forces . The advantages of amalgam restorations include resistance to wear, tolerance to a wide range of clinical placement conditions, and excellent load - bearing properties [13]. However, ama... |
Improvements in the mechanical properties of composite resins and esthetic needs have brought about an increase in the application of these materials . Weak bonding to dentin surface remains, however, is deemed as one of the major problems of composite resin restorations especially in gingival floor of cavities . Appli... |
Advances in chemotherapy and radiotherapy have altered the natural course of disease in patients with systemic cancer, who now live longer than ever before . On the downside, prolonged survival has led to increased incidence of distant spread of disease, leptomeningeal metastasis being one such dreaded complication . H... |
G protein - coupled receptors (gpcrs) compose the largest family of membrane - bound receptors and many members still have unrevealed functions . Efforts have been made to find ligands for gpcrs, and a broad range of ligands, including small organic compounds [1, 2], eicosanoids, peptides, and proteins, have been ident... |
Chronic infection with hepatitis b virus (hbv) results in an estimated 786 000 deaths annually worldwide 1 . Infected individuals may remain asymptomatic for long periods but are at risk of progressive liver disease, and can transmit the virus to other susceptible individuals . The primary marker for screening and labo... |
A 68-year - old man initially presented with a one - month history of cough, heartburn, and episodes of nocturnal regurgitation . Eight months prior to presentation, he had undergone lagb for class iii obesity with a body mass index (bmi) of 41 kg / m . Preoperatively, he had radiographic evidence of a small hiatal her... |
Large scale trials with insecticide treated bed nets (itns) have been shown to have a profound impact on reducing malaria transmission in experimental trials in sub - saharan africa and were recommended for large scale operations . However, this tool did not become practical before the first long lasting insecticide ne... |
This lethal variant results from the inheritance of an autosomal recessive gene and causes abnormal development of cartilage and fibrous connective tissues . These features are broad, long - bone metaphyses (dumbbell shaped) and shortened ribs with pear - shaped vertebral bodies . We report a case of fibrochondrogenesi... |
Matrix metalloproteinases (mmps) are zinc - dependent proteases that are involved not only in the degradation and remodeling of the extracellular matrix but also in processing bioactive molecules, including cell surface receptors, neurotrophic factors, chemokines, and cytokines (kim and joh, 2012). Mmps are indispensab... |
Acute subdural hemorrhage requires emergent neurosurgery or close observation because of its high mortality rate . A number of cases who showed rapid resolution of acute subdural hemorrhage with neurological improvements have been reported2,6,7). Herein, we present a case who showed rapid resolution of acute subdural h... |
The study was conducted in 3 communities in ghana: kwamang (population 8,000), forikrom (population 3,800), and buoyem (population 3,900). Kwamang is part of the ashanti province; buoyem and forikrom are in brong ahafo province (figure 1). Ethics approval was obtained from the committee for human research, publications... |
In recent times in some occupations work in static sedentary postures for long hours in order to perform the tasks required of them . This can cause continuous muscle contraction in the neck and shoulders, which subsequently leads most people to adopt a forward head posture (fhp) in which their chins stick out1 . When ... |
Older adults with a range of comorbidities are often prescribed multiple medications, some of which may impact on their function and cognition, and many have a potential for drug interactions.1 studies showing evidence of benefit from pharmacotherapy have mostly been conducted in younger patients, and it is unclear how... |
Oxidative stress tends to occur during the neonatal period because the younger the gestational age, the lower the antioxidant capacity (ac) and a lower ac tends to result in an increase in free radicals (fr) and reactive oxygen species (ros). Cell damage due to oxidative stress during the neonatal period has been assoc... |
A 42-year - old man with hcv was referred to our hospital in august 2004 because of diarrhea and bloody stool . Ten years before admission, he had been diagnosed with total uc endoscopically and histologically . Colonoscopic examination revealed reddish and edematous mucosa with multiple erosions through the entire col... |
Abdominopelvic fluid collection and abscess management and the outcomes have improved in the recent years due to innovation of the image - guided drainage technique and improvement of surgical procedures (1). Percutaneous drainage (pcd) of abdominopelvic abscess or fluid collection has become an alternative for surgery... |
Presentations at international scientific conferences such as ics and iuga are the most important route for early dissemination and discussion of research findings . Indeed for many studies that never reach full text publication, and in many regions where access to health care publications is limited, the conference ab... |
Developmental dental disorders may be due to abnormalities in the differentiation of the dental lamina and the tooth germs (anomalies in number, size and shape) or to abnormalities in the formation of the dental hard tissues (anomalies in structure). In some, both stages of differentiation are abnormal . Developmental ... |
Absorption, distribution, metabolism, and elimination (adme) studies in drug discovery have always played a critical role in optimizing the drug - like properties of new chemical entities (nce) and increased their probability of success in subsequent stages of the drug discovery process . In order to provide this valua... |
There is a growing interest in using propofol for sedation in endoscopic procedures.14 propofol is commonly used as an anesthetic agent in endoscopic retrograde cholangiopancreatography (ercp). It is a fast - acting drug with a short half - life that results in rapid recovery . It also has a favorable pharmacokinetic p... |
Sinusoidal obstruction syndrome (sos) is a severe adverse event of long - term chemotherapy in patients with colorectal cancer . In contrast, it sometimes appears as a liver mass occurring with local parenchymal hemorrhaging, and is often misdiagnosed as liver metastasis . A 40-year - old woman with rectal cancer under... |
Bladder cancer has a complex etiopathogenesis dependent on various factors: chemical carcinogens (smoking, professional exposure: industry carcinogens), diet (artificial sweeteners, coffee consumption and meat consumption, total fluid intake), previous treatments (pelvic radiation, drug abuse, chronic treatments with a... |
Tennis elbow (te) is not an inflammation of the outside portion of the elbow but rather is the degeneration of the extensor tendon of the humeral lateral epicondyle (le) due to microscopic injuries . Common symptoms include pain, tenderness over the le, pain upon gripping, and dorsiflexion against resistance of the wri... |
Chest pain accounts for approximately 56 million emergency department (ed) visits and 1 in every 50 outpatient visits in the united states, ultimately costing more than $6 billion dollars in annual healthcare costs . While a majority of presentations for chest pain are ultimately deemed non - cardiac in origin, in ligh... |
A flow diagram of the algorithm is shown in figure 1 . To implement this procedure for a given model it is necessary to define bounds for input parameters and model outputs (e.g., steady states or dynamic behavior). If bounds cannot be defined empirically, feasible ranges of parameter values can be asserted from physio... |
In type 2 diabetes mellitus (t2 dm), a prevalent disease characterized by chronic hyperglycemia, the function of -cells responsible for insulin secretion declines progressively together with increasing insulin resistance in target cells . Treatment options for t2 dm include oral antidiabetes drugs (eg, the biguanide me... |
Currently, the combined prevalence of overweight (bmi, body mass index 25 kg / m) and obesity (bmi 30 kg / m), defined by the world health organization (who) [1, 2], has ranged from approximately 50 to 65 percent in large samples of persons with ms [35]. These estimates may not differ considerably from those of nondise... |
Nonalcoholic fatty liver disease (nafld) is a clinicopathological condition characterised by lipid deposition in the liver and is a common cause of liver dysfunction . The prevalence of nafld in asian population ranges from 9% to 45% and is estimated to be about 30% in western population . Apart from an increased risk ... |
Gastric cancer is the second leading cause of death due to malignancy worldwide and occurs most frequently in the age group of 5070 years [13]. However, over the past half century several studies have reported on the clinical and pathological features of gastric carcinoma in young adults in the range of 2%8% in differe... |
Although dualenergy xray absorptiometry (dxa), computed tomography and magnetic resonance imaging (mri) are considered reference methods for identifying low skeletal muscle mass in elderly persons and patients with chronic diseases, access to these instruments may be limited in clinical practice . For this reason, bioe... |
Neurons can release small molecule neurotransmitters very rapidly in part because synaptic vesicles are docked to the membrane at active zones . Docked vesicles can immediately fuse with the plasma membrane (zenisek et al ., 2000) in response to a single action potential (borst and sakmann, 1996; sabatini and regehr, 1... |
Previously, we hypothesized that the development of cognitive processes provided such endowed animals with an additional coping strategy in dealing with stress . This ability depends on a unifying consciousness appearing to control or regulate the many individual processes that potentially summate to make up the mind .... |
Acute respiratory tract infections (artis) are a leading cause of morbidity and mortality in children worldwide[1, 2]. Many viruses are associated with respiratory syndromes in all age groups[3, 4]. However, inadequate diagnostic methods and unknown viral pathogens limit current understanding of arti etiology . One kno... |
Hepatitis c virus (hcv) infection is a major health problem that affects almost 3% of the world's population with a morbidity and mortality rates . Hepatitis c virus is a member of the hepacivirus genus of the flaviviridae family and the viral products (core, e1, e2, ns2, ns3, ns4a, ns4b, ns5a, and ns5b) are processed ... |
Cd36 is a multifunctional signalling molecule with several known ligands, including thrombospondin-1, long chain fatty acids and both native and atherogenic lipoproteins, including oxidised low - density and high - density lipoproteins (reviewed in thorne et al . ). Expressed on a variety of cells and tissues, includin... |
Cytomegalovirus (cmv) a viral pathogen of herpesviridae, can cause serious disease in immunecompromise patients such as solid organ transplant recipients (sotr). Despite our comprehensive knowledge about its management, cmv has been identified as the most frequently occurring complication, which affects mortality and m... |
The presence of pancreatic tissue outside its normal localization and without anatomic and vascular continuity with the normal pancreas is termed heterotopic pancreas (hp); pancreatic rests, ectopic, aberrant, or accessory pancreas are the other terms to describe the entity . Hp may occur throughout the gastrointestina... |
. The prediction of domains from sequence information can improve tertiary structure prediction (1), enhance protein function annotation (2), aid structure determination (3) and guide protein engineering (4) and mutagenesis (5). A number of different methods have been developed to identify domains starting from primary... |
Strauss syndrome, is a non - inheritable and nontransmissible disease affecting medium and small vessels . It is an autoimmune vasculitis leading to tissue necrosis with eosinophilia and eosinophil tissue infiltration . Egpa is accompanied by asthma and involves mainly the blood vessels of the lungs, gastrointestinal s... |
Diaphragmatic rupture is a very rare injury, which occurs in less than 2% of all blunt injuries to the abdominal area . Injury to the diaphragm is most commonly caused by a sudden change in intra - abdominal pressure, most commonly by a blunt blow to the abdominal area . Another cause of diaphragmatic rupture is sudden... |
Irritable bowel syndrome (ibs) is traditionally diagnosed using the rome diagnostic criteria, a symptom - based criteria standard, currently revised as the rome iv criteria.1 the rome iii criteria for ibs had a modest diagnostic ability with a sensitivity of 75% in primary care,2 and a sensitivity of 69% and specificit... |
The most dreaded complication of kawasaki disease reported in the literature over the years is coronary artery disease, which is considered as the main cause of acquired heart disease . We present a rare, if not unique, case of kawasaki disease associated with group a streptococcus pleural effusion in the english langu... |
The prevalence of p. skrjabini in iran has been reported 4.2% in goat, 5.43% in sheep (1, 2), and 0.8% in wild sheep (1, 3). Researchers could analyze the divergences and genetic distances among taxa in the rdna nucleotide sequences to perform phylogenetic relationships analysis and species identification researches . ... |
Pu - erh tea is a special tea species in china and has become one of the most popular beverages in southwestern china and southeast asian, owing to its special flavour properties and potential healthy benefits . It is originated from yunnan province (china) through a special post - fermentative process, using crude gre... |
It has been estimated that about 80% of the western population would suffer some back pain in their lifetime . Ten million people per year are affected in the united states alone, costing roughly around $20 billion, in addition to loss of manpower due the absence from work. [24] mainstay of treatment for patients with ... |
Although psa was once described as a variant of rheumatoid arthritis (ra), it has been included in the group of spondyloarthropathies . Psa was first defined by moll and wright in 1973 in patients who were seronegative for rheumatoid factor (rf) with positive history of psoriasis, current skin or nail psoriasis, and in... |
Chronic obstructive pulmonary disease (copd) is a disabling disease, of which the prevalence increases with age and causes significant morbidity and mortality.1 it is the ninth leading cause of years of life lost according to world health organization global health observatory data (http://www.who.int/gho/en/). In the ... |
The prevalence of diabetes is increasing rapidly worldwide with the influence of expanding economy, abrupt transition of living styles, and social aging . In 2014, there were 387 million people living with diabetes worldwide . The number is predicted to reach 592 million by 2035 of which 46% will still be un - diagnose... |
Eccrine angiomatous hamartoma (eah) is a benign enlargement of eccrine components, accompanied by abundance of vascular channels . The anomaly is usually asymptomatic, but pain, hypertrichosis, and hyperhidrosis have been reported in a few patients . A 26-year - old female presented with a 2.5 cm 1.5 cm blue - colored,... |
More time is required for extraction cases, such as for adult patients, which is a great concern and poses high risk of caries, external root resorption . Thus, accelerating orthodontic tooth movement and the resulting shortening of the treatment duration would be beneficial . Many researchers have utilized different b... |
The burgeoning atrial fibrillation (af) epidemic which currently affects over five million americans is expected to reach a prevalence of nearly 16 million in the united states by 2050 . Another established public health problem with far reaching health consequences is obesity, which has been identified as an independe... |
Epidemiological data have demonstrated that low levels of highdensity lipoprotein cholesterol (hdlc) are a strong and independent predictor of cardiovascular disease . However, the clinical interaction between hdlc and lowdensity lipoprotein cholesterol (ldlc) level, especially the predictive value of hdlc in patients ... |
A 45-year - old female visited the hospital with a palpable mass on the medial aspect of her thigh . The mass was observed by the patient 3 months previously and the size was perceived to be rapidly increasing . Computed tomography of the site showed an 11 cm - sized well - circumscribed mass with heterogeneous intensi... |
The incidence of ureterocele is variable with the highest rate of 1 in 500 and it is generally found in females with duplex system association (95%)[1, 2]. Though there is a female dominance, the nature of the anomaly is more complex in boys . Beginning from the prenatal stage, this anomaly causes different clinical pr... |
When recruited from the cytosol to the membrane, many signaling proteins are activated in response to binding lipid activators with their membrane - binding domains . As a paradigmatic class of membrane - binding domains, c1 domains play vital regulatory roles in a large number of signaling proteins such as protein kin... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.