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The rotational alignment of the component, especially that of the femoral component, is an important part of total knee arthroplasty (tka). Once the rotational alignment of the femoral component has been determined, the tibiofemoral joint can be aligned by the adaption of the tibial component to this alignment . Femora... |
In humans, while the right hemisphere is dominant for visuospatial functions like architecture, geometry, and mathematics, the left hemisphere is dominant for verbal functions like speech, literature, and poetry [1, 2]. A previous study found that left - handers evaluate overall perceptual similarity faster than right ... |
Three patients with sars were admitted to 3 wards of the hospital in early march 2003, at a time when sars was not recognized and no infection control measures were in place . Patient 1, who had imported sars from hong kong, was admitted on march 1 and isolated after 5 days . Patient 2, a nurse who had looked after pat... |
Lead (pb) is a major environmental pollutant, and is highly toxic to the human body . Since the earliest recorded times the metal has been smelted, applied as a cosmetic, painted on buildings, and glazed on ceramic pots (1). On the other hand, lead may be the oldest recognized chemical toxin (2). Signs and symptoms of ... |
Brucella endocarditis (be) is a rare but severe and potentially lethal manifestation of brucellosis . Pre - existing valves lesions and prosthetic valves (pv) are favorable for be . We represent the case of a 46-year - old man who was treated at the clinic for infectious diseases, clinical center of sarajevo university... |
Acetylcholine (ach), traditionally regarded solely as a neurotransmitter, is synthesized in cholinergic neurons and released via vesicular machinery in response to physiological and pharmacological stimulation . Ach acts through nicotinic and muscarinic receptors in nerves and peripheral tissues . In 1966, morris repor... |
Recent reviews of consecutive knee arthroscopies have demonstrated an incidence of chondral defects ranging from 60% to 66%, irrespective of the surgical indication . These lesions have been shown to have poor intrinsic potential for spontaneous healing and may predispose patients to the development of future joint deg... |
Age - period - cohort analyses can help evaluate causes of past population - level health trends, predict future health trends, and illuminate causes of individual - level susceptibility to health outcomes . All previous age - period - cohort analysis of obesity examined obesity assessed by body mass index (bmi). This ... |
The surveillance of parasites and pathogens in wildlife populations has received international attention, since wildlife conservation outcomes can be affected by parasitic infections (van riper et al ., 1986, levin et al ., 2013), and since wildlife are increasingly found to host pathogens that can infect humans (guber... |
Being a major organ of the immune system, thymus plays a key role in the t cell immunity formation [1, 2]. An overt lowering of thymus functional activity in humans can be traced from the beginning of puberty and is associated with an early involution of this organ [3, 4]. Thymus involution is largely manifested by the... |
Although the mass occurrence of planktonic algae in lakes and reservoirs has been for many years one of the main problems in water quality management, there is no generally accepted, inexpensive and environmentally safe method of reducing this phenomenon . One promising technique is an application of barley straw, whic... |
The use of calcium hydroxide [ca(oh)2] as intracanal dressing has been recommended to induce apexification, to control internal and external inflammatory root reabsorption and in the treatment of necrotic teeth with periapical lesions . However, failing to completely remove the dressing may interfere with the seal, adh... |
By 2030, the number of older immigrants living in the united states is expected to have increased by 40 percent (arias 2010). U.s .- born racial / ethnic minority groups will also continue to grow and make up an increasing share of the older population (vincent and velkoff 2010). These shifts will change the demographi... |
Obesity is a proinflammatory burning health issue recognized globally associated with increased risk of a cluster of risk factors which are representative of the metabolic syndrome . Energy uptake overrides expenditure causing a disruption of cellular functions augmenting insufficient appetite regulation, thereby leadi... |
Liver cancer is one of the leading primary cancers and the main cause of death in korea . The 5-year survival rates have improved in liver cancer patients diagnosed from 2008 to 2012 compared with those diagnosed from 1993 to 1995 . However, the prognosis of liver cancer is still poor compared to that of other cancer p... |
Large vestibular aqueduct syndrome (lvas) or enlarged vestibular aqueduct syndrome (evas) is a radiological diagnosis, which clinically manifests as sudden, fluctuating or progressive hearing loss . Commonly, diagnosis is made during early childhood, either associated with inner ear anomaly, or congenital disorders; or... |
The renal cytokine hormone erythropoietin (epo) regulates bone marrow erythrocyte production by stimulating the differentiation and inhibiting the apoptosis of erythroid progenitor cells (de maria et al ., 1999; liu et al ., however, epo also bears extrahematopoietic properties that are transduced by epo receptors (epo... |
Moderate alcohol consumption can transiently improve movement - associated symptoms such as essential tremors, dystonias [3, 4], and tics . However, chronic alcohol consumption can trigger or aggravate hyperkinetic conditions such as akathisia, chorea, and myoclonus [6, 7]. Delirium tremens is a severe form of alcohol ... |
Patent foramen ovale (pfo) is observed in 25% of the general population; 46% of cryptogenic ischemic strokes are associated with its presence [1, 2]. Diagnostic examinations focusing on pfo are recommended in all patients following a neurological incident before the age of 55 . The standard examination performed to det... |
Peripheral arterial disease (pad), an obstructive atherosclerotic disease in the lower extremities, was repeatedly found to be associated with cardiovascular diseases, stroke, mortality, or decreased quality of life in different populations . The prevalence of pad has been of increasing concern around the world for the... |
Carbon nanotubes (cnts) have attracted wide attention both in the research and industrial communities because of their unique structure and properties . In particular, field electron emission from cnts has been proposed to be one of the most promising as far as its practical application is concerned . This is because c... |
Oral squamous cell carcinoma is most common in oral malignancies, but gingival squamous cell carcinoma (gscc) is a rare tumor which accounts for less than 10% of all oral malignancies . Gscc typically resembles common periodontal lesion and has a high risk of metastasis and bone invasion with delayed diagnosis . Cispla... |
The bacillus calmette - guerin (bcg) has been used as intravesical immunotherapy for superficial urothelial bladder carcinoma in preventing its recurrence . However, side effects range from locally and self - limited complications to systemic and life - threatening adverse reactions . Osteoarticular complications after... |
A number of studies1,2 have focused on the specific interaction between bipolar disorder (bp) and stress in the field of psychiatry . Extensive research has been conducted on dysregulation of the hypothalamus pituitary adrenal (hpa) axis and its association with bp.3 this dysregulation has become a promising target for... |
Neuroferritinopathy is an autosomal dominant neurodegenerative disorder that is grouped within a family of disorders called neurodegeneration with brain iron accumulation (nbia). The disease most often includes a movement disorder, cognitive decline, and typical magnetic resonance imaging (mri) appearance . The resulti... |
Osseointegration is a complex phenomenon and a prerequisite for the clinical success of bone - anchored dental and orthopedic implants.1 experimental studies provide evidence that bone formation could be promoted by implant surface modifications, largely dependent on the alterations of surface topography and roughness.... |
Approximately 33 to 73% of stroke patients are reported to experience dysphagia1, a disorder that causes difficulty with chewing and swallowing food . The condition can cause very serious complications such as aspiration pneumonia, dehydration, and malnutrition, and may occasionally lead to death2 . Enabling dysphagia ... |
Hydrophilic soft contact lenses were invented in 1961 by czechoslovakian chemist professor otto wichterle and first commercially introduced in the united states by bausch & lomb in 1971 . In the more than three decades since their introduction, hydrophilic soft contact lenses have proven a comparatively safe and effect... |
Epithelioid hemangioendothelioma is a rare vascular tumor that usually develops in the lung, liver, bone, and soft tissue, and has a prognosis varying from benign to malignant . Hepatic epithelioid hemangioendothelioma usually occurs in adult women and presents as multiple masses, and its confirmatory diagnosis is made... |
The online version of this article (doi:10.1007/s11999 - 008 - 0571 - 2) contains supplementary material, which is available to authorized users . Below is the link to the electronic supplementary material . For article #1 (1949): reprinted with permission and elsevier masson editeur from merle daubign r, cauchoix j, r... |
A watershed finding regarding the etiology of mcc was the discovery in 2008 of the merkel cell polyomavirus by the chang - moore group (feng et al ., 2008). They demonstrated that in most mccs the viral dna was clonally integrated into the host cell dna, indicating that each tumor arose from a single cell and that the ... |
Fangji huangqi tang (fht) is a classical formula of traditional chinese medicine (tcm). It was firstly recorded in jing gui yao lue by zhongjing zhang in the han dynasty . The formula consisted of four herbs, including stephania tetrandra s. moore, astragalus membranaceus (fisch .) Bge ., atractylodes macrocephala koid... |
Cardiometabolic risk (cmr), a construct that comprises a cluster of risk factors for cardiovascular disease and type 2 diabetes mellitus, poses one of the largest public health challenges in the united states (us).1, 2 the prevalence of cmr factors such as hypertension (33%), overweight / obesity (69%), diabetes mellit... |
Breast cancer is the commonest malignancy in women worldwide and the preoperative evaluation of breast lumps is an essential part of the management of breast lesions [1, 2]. The use of core needle biopsy in the management of palpable breast lumps in recent times has been increasing [3, 4]. This is because core needle b... |
Duchenne muscular dystrophy (dmd) and becker muscular dystrophy (bmd) are allelic disorders of the dystrophin gene at the xp21 locus1,2). Dystrophin plays an essential structural role in both cardiac and skeletal muscle, protecting the sarcolemma from mechanical stresses of muscle contraction3). Whereas dmd is characte... |
Streptococcus pneumoniae (pneumococcus) is a leading cause of bacterial illnesses among children throughout the world, responsible for invasive pneumococcal disease (ipd) (e.g. Meningitis, sepsis, bacteraemic pneumonia and bacteraemia) and non - ipd (e.g. Pneumonia, acute otitis media and sinusitis). A 20-year (1980199... |
Exercise therapy is at the core of rehabilitation for chronic obstructive pulmonary disease (copd)1,2,3, the incidence of which continues to increase worldwide4,5,6 . Both endurance and strength training focusing on the lower limbs can decrease the lactic acid concentration in the blood, carbon dioxide production, and ... |
Forensic odontology plays a significant role in identification of individuals in case of crime investigations or during autopsy . Forensic odontology becomes even more important when bodies are decomposed, skeletonized, or mutilated . This is because dental hard tissues have some morphological characteristics, and perh... |
Most poor people seek help at public run hospitals where services are free, and those from families below the poverty line (bpl) are exempted from payments for medicines and investigations . While this is helpful, there are other hidden costs which the family has to bear . Patients often need to buy medicines which are... |
A diverse number of interactions between bone and immune cells occur within the bone microenvironment . Bone and immune cells share the same progenitors residing in the bone marrow and these progenitors are under the effect of the same molecules including cytokines; these molecules can have a high influence in the hema... |
Ludwig's angina is a potentially life - threatening infection of the sublingual and submandibular space which involves the neck and floor of the mouth . It is one of the rare medical emergencies in a critical care setting, which could turn out to be devastating if unidentified at the earliest . If angioneurotic edema i... |
The acquired neuropathies include the acute inflammatory demyelinating polyneuropathy (aidp, guillain - barr syndrome) and the chronic inflammatory demyelinating polyneuropathy (cidp).1 the purpose of this manuscript is to review the history of development of knowledge about guillain - barr syndrome (gbs) from the time... |
Inflammatory bowel disease (ibd) is a chronic relapsing inflammatory disorder of the gastrointestinal tract that comprises two major conditions: crohn's disease (cd) and ulcerative colitis (uc). These pathologies are characterized by abdominal pain, fever, chronic diarrhea, and rectal bleeding due to ulceration of the ... |
The rapid dissemination of highly pathogenic h5n1 avian influenza viruses and evolution of their antigenic diversity pose a pandemic threat to public health . Vaccination remains one of the most effective measures to prevent severe illness and death from pandemic influenza . One is based on chemically inactivated deter... |
Lipoprotein lipase (lpl) deficiency is a rare condition characterized by high plasma triglycerides, low hdlcholesterol, and the presence of fasting chylomicrons due to a mutation of a key enzyme involved in the hydrolysis and removal of triglycerides from plasma 1 . Besides lpl, several additional loci have been identi... |
Safe drinking water is a fundamental human right and if contaminated with opportunistic pathogenic environmental bacteria, it may have health implications for consumers [2, 3]. Human health should therefore be protected by preventing microbial contamination of water that is intended for consumption . In rural communiti... |
Animal model of sciatic nerve transection: sprague - dawley rats (1012 weeks) were used for this study . The institution s guidelines for the care and use of laboratory animals were followed . Rats were anesthetized by intraperitoneal (i.p .) Injection of ketamine (75 mg / kg). Under aseptic conditions, sciatic nerves ... |
All well - differentiated neoplasms are called neuroendocrine tumors (nets), and all poorly differentiated neoplasms are termed neuroendocrine carcinomas . Rectal nets <10 mm in size have a very low risk of lymph node metastasis . However, the vertical margin remains positive after conventional endoscopic therapy becau... |
Liver transplantation (lt) is an effective treatment for end - stage liver disease . Portal vein (pv) complications after lt that include pv stenosis and pv thrombosis are rare, but can be devastating and lead to graft failure . If not promptly treated, pv stenosis and pv thrombosis may lead to pv occlusion . Pv occlus... |
The incidence of varicoceles in both men and adolescent boys is approximately 15% [1 - 3]. In men evaluated for an infertility problem, 37 - 41% are diagnosed with a left varicocele but only 40% will achieve paternity when the varicocele is surgically corrected . It would be illogical to recommend varicocele repair on ... |
A cutaneous sinus of dental origin is a relatively uncommon occurrence and may be easily misdiagnosed . They do not always arise close to the underlying infection and dental symptoms may be absent (1). Often patients seek care from general physicians and surgeons with other diagnoses being made such as furuncles, basal... |
A 55-year - old male patient visited our clinic for the chief complaint of sudden - onset vision decrease after nd: yag capsulotomy in a local clinic . At the time of admission, the uncorrected visual acuity was 20/1000 and the intraocular pressure was 15 mm hg . At 22 months before the dislocation of the iol, the pati... |
First described in 2001, robotic - assisted radical prostatectomy (rap) now constitutes a substantial portion of the minimally invasive prostatectomy market, as 2 new hospitals acquire a da vinci robot per week (intuitive surgical, personal communication october 2006). The benefits associated with transitioning from op... |
Data were collected from patients with type 1 diabetes enrolled in several multicenter diapep277 phase ii studies with a prospective, randomized, double - blind, parallel - group, and placebo - controlled design . Diagnosis of type 1 diabetes and the inclusion / exclusion criteria have been previously published (1113).... |
The vacuum disc phenomenon, known as a presence of gas in the intervertebral disc space, is a relatively common radiological finding, especially on computed tomography (ct) finding1,6,8). Although its clinical importance is low, sometimes it can cause different clinical pattern12). Patients with epidural gas may compla... |
Several studies suggest that idiopathic scoliosis is a familial condition that has a multifactorial etiology [13, 25]. Twin studies will diminish the effects of environment and allow an understanding of genetics of adolescent idiopathic scoliosis . The fact that monozygotic twins have a significantly higher concordance... |
Burning mouth syndrome (bms) is defined as the sensation of burning or pain on the oral mucous membrane, without evidence of abnormalities in the direct inspection, clinical exam or subsidiary investigation . Besides pain and tingling, bms is often characterized by dry mouth and taste perversion [1, 2]. Bms is more pre... |
It is generally acknowledged that central nervous system (cns) disorders involve microglial activation and that progression and resolution of many diseases depend in part on the actions of microglia . As resident inflammatory cells of the cns, microglia potentially modulate inflammatory processes . However, microglial ... |
A malignant mixed mllerian tumor (mmmt) that develops from the female genital tract is a rare clinical entity, accounting for less than 1% of all gynecological malignancies . Since mllerian ducts develop to form the fallopian tubes, uterus and the upper third of the vagina, mmmts are usually found in these structures o... |
Vitamin c (ascorbate) is an essential nutrient in humans, and insufficient dietary intake leads to the potentially fatal deficiency disease, scurvy . It is an essential cofactor for a variety of dioxygenase enzymes that hydroxylate amino acids in the synthesis of pro - collagen, carnitine, hormones and neurotransmitter... |
Apprehension about a possible adverse reproductive outcome haunts nearly every anaesthesiologist . Despite an extensive review of literature, it is not clear if the practice of anaesthesia is associated with a higher risk of a poor reproductive outcome than the general population . The introduction of newer inhalationa... |
Diabetes is a major global health problem, which currently affects millions of people worldwide with high and escalating costs to societies.1,2 we have established the diabetes impact study 2013 with the aim to provide an updated account of the current and future epidemiological profile of diabetes in denmark together ... |
Intracellular infections with pathogens such as viruses and certain bacteria are defeated by cytotoxic t lymphocytes (ctl). The ctl t - cell receptor (tcr) recognizes foreign peptides in complex with major histocompatibility complex (mhc) class i molecules on the surface of the infected cells . Mhc class i molecules pr... |
The tm4sf2 gene on xp11.4 encodes tetraspanin 7 (tspan7), member of the tetraspanin superfamily of evolutionarily - conserved membrane proteins that associate dynamically with numerous partner proteins in tetraspanin - enriched microdomains (tems) of the plasma membrane (boucheix and rubinstein, 2001). Tetraspanins reg... |
It is well established that allergic rhinitis and asthma frequently coexist in the same subject, and the united airway disease model has been proposed to describe a unique disease with manifestations in different sites of the respiratory system . In addition, large studies have suggested a link between the severity and... |
Shiga - toxin producing escherichia coli (stec) is capable of naturally colonizing within the gastrointestinal tract of cattle without causing illness . Human consumption of products contaminated with stec can cause the severe illnesses hemorrhagic colitis and hemorrhagic uremic syndrome [2, 3]. The most notorious stec... |
Dental caries is the single most common biofilm dependent oral infectious disease worldwide that results from the interaction of specific bacterial and salivary constituents with dietary carbohydrates in a biofilm tightly adherent on the tooth surface . Dental caries is most likely the result of a polymicrobial infecti... |
However, not all patients may understand the clear liquid component of the preparation instructions, resulting in poor quality preparation with subsequent delays in diagnosis and treatment . In general, patient comprehension of medical instructions is poor since most americans read at the equivalent of an 8th or 9th gr... |
The concept of improving the quality of healthcare service has been repeatedly discussed in recent years . Patients who are satisfied with their service experience are more likely to come back to the hospital in the future . Many studies have regarded patient waiting time as a significant component of patient satisfact... |
The most commonly used terms to describe vocal fold mobility disorders are paralysis, meaning complete immobility, paresis for hypomobility, and fixation that describes an immobile vocal fold due to mechanical obstruction of its movement, such as arthritis of the cricoarytenoid joint or scarring of the posterior commis... |
In india, marital rates of persons with schizophrenia are high compared to western countries . Parenting difficulties in women with psychosis are common and could be due to social cognitive impairments, specific positive symptoms the presence of social stressors (e.g. Chronic social adversity, stigma or a lack of prote... |
Macrophages play important roles in a host's immune defense system during infection as well as in the processes of disease development . Activation of macrophages by stimuli, such as the bacterial endotoxin, lipopolysaccharide (lps), and viruses, increases the production of numerous inflammatory mediators, including ni... |
The conceptual simplicity of the implicit solvation (solvent treated as a structureless continuum dielectric medium) framework facilitates fast quantitative estimates of solvation effects that are key in biomolecular computation . In this framework, one often approximates the solvation free energy free energy change to... |
The success of renal transplantation continues to be limited by ischemia reperfusion injury, which is the dominant mechanism in the development of delayed graft function (dgf). Commonly defined as the need for dialysis within seven days of transplant, dgf is greatly influenced by factors that lead to greater ischemic i... |
A 70-year - old female presented with a history of painless swelling of the left lower eyelid for one year (fig . Her visual acuity was 20 / 20 (left eye), and a slitlamp examination of the left eye revealed no abnormalities except for corneal granular dystrophy . The lower eyelid of the left eye was diffusely swollen ... |
It is widely available in the bangladeshi market as an effective preparation to treat lumbago, sciatia and arthritic pain of joints . Our present studies make an attempt toward identifying probable antinociceptive and anti - inflammatory effect and its mechanisms of drk . Drk, at three doses, (10 ml / kg, 20 ml / kg, a... |
A 46-year - old female patient visited our hospital with pain in the right posterior neck area, which had continued since she had fallen from a chair six months previously . She said that she had fallen down from a chair with small wheels in her house at the time of the accident . The degree of pain was 8/10 on the vis... |
The disease is reported in 88 countries around the world, and its prevalence is estimated to be approximately 12 million annually and about 350 million people are at the risk of the disease [1, 2]. About 90% of cases of cutaneous leishmaniasis are found in brazil, afghanistan, iran, peru, saudi arabia, and syria, and a... |
Shiga toxins (stxs, also referred to as verotoxins), a family of bacterial protein toxins generated by stx producing - escherichia coli (stec), such as e. coli serotype o157:h7, are believed to cause hemorrhagic colitis and hemolytic uremic syndrome (hus) (1, 2). Shiga toxins are amongst ab5 toxins, which consist of a ... |
Chronic primary mitral regurgitation (mr) due to myxomatous mitral valve disease is an important cause of morbidity and mortality . It causes progressive left ventricular (lv) dilatation and irreversible myocardial damage and is associated with eccentric hypertrophy and complex lv adaptive remodeling . This remodeling ... |
Good is a contested matter, since there is no uniform label and way of doing good care. Instead what is defined as good care is highly variable from one situation to the other . Anne - mei the showed through her anthropological research in dutch nursing homes, how in daily care delivery, caregivers decide what good car... |
Coronary artery stenting has become the preferred technique for revascularization in a patient with coronary artery disease . Patients with coronary stents are strictly advised to continue dual antiplatelet therapy, clopidogrel and aspirin, for a duration of atleast 1 year to allow re - endothelialization and prevent a... |
Cancer stem - like cells glial fibrillary acidic protein inhibitor of apoptosis nuclear factor kappa b glioblastoma multiforme (gbm), the most common primary malignant brain tumor in adults, is known for its high aggressiveness and inherent resistance to current treatment regimens . Cancer stem - like cells (cslcs) are... |
Cancer is leading cause of death too with 7.6 million deaths (around 13% of all deaths) in 2008. (1) total 13% of the annual death worldwide is cancer related, and 70% of these are in the low- and middle - income countries. (2) it is estimated that 7.4 million people died of cancer in 2004, and if current trends contin... |
Testicular cancer (tc) is a rare disease, with 300 cases per year in denmark ., it represents the most curable solid tumor with a 10-year survival of 90%95%.1 with the high cure rate and young age at diagnosis, posttreatment morbidity plays a central role . Previous studies have shown an increased risk of secondary can... |
Its diagnosis is often delayed because its symptoms and imaging mimic occlusive atherosclerotic disease or vasculitis (1), thus it is primarily diagnosed during surgery or an autopsy (2). Polyarteritis nodosa (pan) is a systemic necrotizing vasculitis that typically affects medium - sized muscular arteries . Patients w... |
Verrucous papillary lesions (vpls) of the oral cavity are diagnostically challenging as they include a spectrum of benign, potentially malignant, and frankly malignant lesions . A majority of the benign vpls have a viral aetiology and include the more commonly occurring squamous papilloma along with verruca vulgaris, f... |
Whole disc organ culture is needed for preclinical testing of biological repair of the degenerate intervertebral disc . Such organ culture is hampered by two major limitations: first, obtaining adequate nutrition through the calcified cartilage end plates and adjacent vertebral bone; second, by loss of tissue integrity... |
Bone marrow fibrosis is known to occur in several neoplastic and non - neoplastic conditions . Among neoplastic conditions such as acute leukemia, acute promyelocytic leukemia (apl) presenting with marrow fibrosis is a rare entity, with few cases reported in the past,, . In one case series a reversible bone marrow coll... |
Deep brain stimulation (dbs) has demonstrated significant therapeutic benefits in (i) treating symptoms relating to neurological motor disorders including parkinson's disease, essential tremor, and dystonia, (ii) controlling epilepsy, and (iii) providing relief from chronic pain . Dbs has been also employed for treatme... |
Sarcoidosis is an idiopathic, inflammatory condition primarily encountered within the lungs but very rarely identified in the peritoneum . Case study: a 34-year - old woman presented with pleural effusion, ascites and an adnexal mass, indicative of ovarian cancer . However, 2 years later, she developed another pelvic m... |
Scoliosis surgery can often be complicated by postoperative paralytic ileus and superior mesenteric artery (sma) syndrome.1234 both, conditions have usually a benign course and resolution of the symptoms should be expected with early instigation of conservative management . Their clinical appearance can, however, mask ... |
Central pontine myelinolysis (cpm) is an acquired demyelinating lesion of the basis pontis that typically occurs after rapid correction of hyponatremia . It is an uncommon condition with predilection for the central portion of the basis pontis, although axons in the putamina, caudate nuclei, thalami, cerebellum, spleni... |
Visualization of bonding interactions between atoms and molecules is a long - standing quest in computational chemistry . During its development the main interest lies in creating a tool that enables not only to see the interaction but also to interpret its character and properties . There is no general agreement on ho... |
The electronic databases (beginning in 1950 until july 2010) medline and embase were searched for the medical subject headings (mesh) diabetic retinopathy and mortality or cardiovascular disease to identify observational studies that report the incidence of all - cause mortality, and fatal and nonfatal cv events in dia... |
Clinical diagnosis of patients presenting with extrapyramidal features is often problematic as signs and symptoms suggestive of parkinson s disease may be present in several parkinsonian syndromes . The diagnostic algorithm can be even more complex if additional cognitive deficits are present . These cases, particularl... |
Despite pharmacological advances, about 10%30% of patients with schizophrenia exhibit little or no response to antipsychotic medications, and persistent symptoms make it difficult for these patients to re - enter society . Clozapine is effective against treatment - resistant schizophrenia (trs) and was introduced to ja... |
Patients afflicted with congenital fibrosis of the extraocular muscles type i (cfeom - i) usually suffer from a nonprogressive restrictive motility disorder, with or without ptosis, with the eyes usually fixed in an infraducted position.1 both strabismus surgery and ptosis correction are required to achieve an aestheti... |
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