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Microglia, macrophage - like immune cells in the central nervous system (cns), cluster around the senile plaques that along with polymorphous amyloid (a) deposits are the pathological hallmarks of alzheimer's disease (ad). Microglia have a biphasic neurotoxic - neuroprotective role in the pathogenesis of ad . In regard... |
There is growing evidence that the impact of plasmodium vivax has been underestimated in developing and poor countries.1,2 the difficulty of differential diagnosis and lack of proper treatment of both blood - stage and latent parasites are two of the reasons for the prevalence of vivax malaria . A 28-year - old japanes... |
Synovial cysts are infrequent findings in the spine; when they appear, they are mostly located in the lumbar area . The pathology arises from the facet joint and may cause pain, radiculopathy or myelopathy, . On the background of the international literature, we report this uncommon case of a cervical synovial cyst ass... |
This is a retrospective case series of all patients who underwent concomitant tethered cord release and growing - rod insertion with neurophysiological monitoring at our institution . Patients were included if they had a diagnosis of progressive eos (congenital, infantile, juvenile) requiring either growing - rod or ve... |
1) is the major active component of traditional herbal medicine peucedanum praeruptorum dunn and has been proved to be a novel ca influx blocker (1). It has been reported that pd - ia could inhibit the expression of apoptosis related proteins, reduce the level of proinflammatory factors, and increase intermediate filam... |
Single cell gel electrophoresis (scge) is a sensitive technique for measuring and analyzing dna damage in eukaryotic cells . It is also known as comet assay, which is a rapid, simple, visual and reproducible biochemical technique for measuring and analyzing dna single - stranded breaks and/or alkali labile sites within... |
Malaria is a major public health concern in the world and more especially among pregnant women and children because of their vulnerability . As such approximately half of the world's population is at risk of malaria and nearly one million people die of the disease each year [2, 3]. However, asia, latin america, the mid... |
Thiopurine therapy, including 6-mercaptopurine (mp) and azathioprine, is a well - established steroid - sparing maintenance strategy for inflammatory bowel disease (ibd). However, many patients discontinue this therapy because of lack of efficacy or intractable adverse events . For some of these patients thiopurine met... |
The prevalence of prostatitis is 8.2% (range 2.2%9.7%) and the national institutes of health (nih) classified prostatitis into four categories: acute bacterial, chronic bacterial, chronic prostatitis / chronic pelvic pain syndrome, and asymptomatic (1). Acute bacterial prostatitis (abp) is a rare disease accounting for... |
A detailed methodology of the prospective metabolism and islet cell evaluation (promise) cohort study has been published previously (19,24). In brief, promise study participants, aged 30 years, were recruited from toronto and london, ontario, canada, between may 2004 and december 2006 . Participants were at high risk f... |
Hypertension is defined as a sustained systolic blood pressure of greater than 140 mmhg, a diastolic blood pressure of greater than 90 mmhg, or both . Ninety five percent of hypertensives suffer from essential hypertension (eh) with the remaining 5% exhibiting high blood pressure due to some underlying disorder such as... |
Disability rates are expected to increase with the aging of the baby boomer population . Indeed, recent national health and nutrition examination survey (nhanes) data suggest that for those 6069 years old, the prevalence of disability in activities of daily living, instrumental activities of daily living, and mobility ... |
Endodontic treatment of a pulpless tooth with periapical radiolucency of a considerable size either cyst or granuloma always has a question of success . For such cases, earlier the endodontic treatment followed by surgery, i.e., apicectomy was the treatment procedure to be done to remove the pathology . However, in mod... |
Precise root canal length determination using the apical constriction or the apical foramen (af) as references is an extremely relevant factor for the success of endodontic treatments . Electronic root canal length measurement devices (erclmds) are considered efficient tools for this purpose, achieving precision percen... |
Fallopian tube prolapse after hysterectomy into the vaginal vault is a rare occurrence, although failure to recognized this has lead to its under reporting . Since the first description of this condition by piozzi in 1902, fewer than 100 cases have been reported so far, the majority following vaginal hysterectomy proba... |
Implantation is a complex process that requires synchronization between the events that occur in the uterus and that of the embryo . Uterine events are under the influence of sex steroids which include alteration in the luminal fluid volume, ph, metabolites, and ionic compositions . Under the influence of oestrogen (e)... |
Fear of hypoglycaemia and gain in body weight are barriers for initiation of insulin therapy . Modern insulin analogues are a convenient new approach or tool to glycaemic control, associated with low number of hypoglycaemia and favourable weight change . A1chieve, a multinational, 24-week, non - interventional study, a... |
To better characterize the patient s clinical isolate, we subjected the organism to whole - genome sequencing by using the miseq platform (illumina, san diego, ca, usa). In brief, dna was digested by using nebnext dsdna fragmentase and then end - repaired and a - tailed by using e. coli dna polymerase i, t4 pnk, and ta... |
The lacrimal caruncle, or caruncula lacrimalis, is a small, pink, globular nodule at the medial canthus of the eye, and it consists of skin, hair follicles, sebaceous glands, sweat glands, and accessory lacrimal tissue . Lesions of the caruncle are rare, and the lesions developing from the caruncle are very diverse mak... |
The rapid growth in the number of investigators using diverse 3d intestinal tissue culture systems (figure 1) has outpaced the adoption of standardized nomenclature . Cultured tissues that retain some amount of complex in vivo function and cellular diversity are considered organotypic, a term encompassing both cultured... |
One is unilateral pa, mainly due to aldosteroneproducing adenoma (apa) and the other is bilateral pa, mainly due to idiopathic hyperaldosteronism (iha). It is important to determine the pa subtype because the recommended treatment for apa is an adrenalectomy and that for iha is pharmacological therapy with a mineraloco... |
Functional imaging with positron emission tomography (pet) or functional magnetic resonance imaging (fmri) has enabled further investigation of migraine pathophysiology in recent years [15]. However, the dynamic nature of perfusion abnormalities that occur with migraine limits the application of these methods in the ev... |
Prokaryotes and lower eukaryotes are able to move towards favorable and away from unfavorable conditions including chemicals and light, referred to as chemotaxis and phototaxis, respectively [1, 2]. Repellent phototaxis in the halophilic archaeon natronomonas pharaonis (also known as natronobacterium pharaonis) is init... |
Herring classified coxa vara into developmental coxa vara (dcv), acquired coxa vara and coxa vara associated with congenital femoral deficiency.1 while acquired coxa vara may be due to a variety of causes such as trauma, slipped capital femoral epiphysis, perthes disease, infection, rickets and skeletal dysplasia, the ... |
Alcoholic liver disease (ald) is an important worldwide public health issue affecting millions of people every year . The first stage of liver injury is steatosis, an abnormal retention of lipids within the hepatocytes observed as a consequence of acute or chronic ingestion of ethanol, followed by reduced -oxidation of... |
The fascinating physicochemical properties of nanomaterials promise to syncretize disease treatments and real - time diagnostics into a single theranostic platform for the goal of personalized medicine . Intelligent activation with internal or external stimuli such as ph, temperature, redox potential, magnetism, ultras... |
A 33-year - old female was transferred to the emergency department with severe groin pain after having emergency cesarean resection due to cephalopelvic disproportion 5 days earlier . She had burning, lancinating, and intermittent pain in the left groin region, especially the area of the superomedial thigh, the mons pu... |
Erps are transient, modifications in electromagnetic brain signals, which are time - locked to cognitive, motor, or sensory processing . They represent activity directly at the level of neuronal networks and hence form a good method for studying the working brain and obtaining neurophysiological indices of attentional ... |
Vanishing bone disease, popularly known as gorham's disease (gd), is an extremely rare disorder of unknown etiology . The pathogenesis and treatment of this disorder is still a mystery . Though known as gorham stout disease, it was first described by jackson in 1838.1 in 1955, gorham and stout described a series of 24 ... |
Heavy and/or prolonged menstrual bleeding (hmb) stands among the most common presentations in the acute gynecology units and accounts for up to 70% of all gynecological consultations in the peri- and postmenopausal years . Hysterectomy represents the ultimate treatment for hmb; however, it might have its potential psyc... |
The swine flu (h1n1) pandemic was confirmed on june 11th, 2009 by the world health organisation (who). The who declared the pandemic over by august 10th, 2010, by which time 214 countries had reported laboratory confirmed cases, which included 18 449 deaths . In contrast to seasonal influenza epidemics, in the 2009 h1n... |
The primary treatment guidelines of acute ischemic stroke are based on time - guided criteria rather than penumbral considerations . For nearly two decades studies have confirmed that intravenous tissue plasminogen activator (tpa) is safe and effective if given within the first 3 h of stroke symptom onset and subsequen... |
2007; victoriano et al . 2009), but with over 1,000 annual cases per 100,000 inhabitants (up to 53 confirmed cases per year in 4,200 inhabitants), the island of futuna (1417 s, 17808 w) has the highest prevalence worldwide (centre national de rfrence de la leptospirose 2010). 2009) and are considered as a major threat ... |
Methods to guide excision of impalpable lesions include hook - wire insertion (hwl), intra - operative ultrasound (ious) and radio - guided occult lesion localisation (roll) using the injection of tc - labelled colloidal human serum albumin.1 a new technique, roll using i seeds (rollis) offers many advantages2 as illus... |
Following traumatic spleen rupture or surgery, heterotrophic autotransplantation of the spleen tissue occurs in a process called splenosis . It can occur anywhere in the abdominal cavity and can even reach the brain tissue . Due to the fact that splenosis is a rare incident, the pathogenesis is not fully understood . Y... |
Necrotiszng fasciitis is a rare, rapidly progressing and severe infection of subcutaneous soft tissue and underlying fascia [18]. Vasculitis and microthrombi formation with eventual intravascular coagulation and spreading necrosis are characteristic pathophysiological features of the infection and present clinically wi... |
Cancer chemotherapy is landmarked by the indisputable clinical success of cisplatin, with ca . Disappointingly, however, platinum therapy suffers from several drawbacks, which include acquired resistance, limited spectrum of activity, and toxic side effects . Consequently, constant efforts are being made to develop new... |
Endoscopic retrograde cholangiopancreatography (ercp) is one of several popular procedures for biliary or pancreatic duct diseases . Recently, it has been used in lithotripsy, endoprosthesis placement, stone extraction, and sphincterotomy . However, it has also many complications from mild inflammation to severe life -... |
The study by rech and colleagues in the previous issue of critical care describes the use of neuron - specific enolase (nse) to inform an early prognosis in 43 patients who survived for more than 12 hours after resuscitation from in - hospital cardiac arrest . A reliable early neurologic prognosis can help families mak... |
Osteoporosis is a chronic, progressive disease characterized by reduced bone mass and microarchitectural deterioration of bone, involving an extensive fragility and a subsequent increase in fracture risk . Fracture risk increases with age and is often associated with an increased bone remodeling resulting in bone resor... |
Hair loss in the african female is multifactorial in origin . It is dry, kinky and prone to fractures in its natural state . Various hair grooming practices attempting to improve its appearance have also been implicated in hair loss . Hair loss may result from scalp or hair shaft abnormalities induced by physical or ch... |
Immunoglobulin g4-related disease (igg4-rd) is a systemic autoimmune disease first renowned as sclerosing pancreatitis, corresponding to type 1 autoimmune pancreatitis (aip). Have not been established, an appropriate identification of the disease includes a panel of histological, radiological and biological features cu... |
A 33-year - old male was born with transposition of the great arteries (tga). At the age of 1 month, he underwent rashkind septostomy . There was also unroofing of the coronary sinus and persistent draining of the left superior caval vein directly to the left atrium between the appendage and the left pulmonary veins . ... |
The components evolving pungency in chili peppers have been established as a mixture of acid amides of vanillylamine and c8 to c13 fatty acids, also known as capsaicinoids . Capsaicinoids are secondary metabolites and are synthesised by glands at the join of the placenta and the pod wall of pungent peppers . The effect... |
Carcinoma cervix is a common malignancy of the female genital tract and radiotherapy is a standard mode of management . Although with the recent advances, the complications associated with radiotherapy have reduced, we do continue to come across long - term complications of radiotherapy given decades ago for different ... |
The mechanism of action for methotrexate lies in its intrinsic ability to effectively block the synthesis of tetrahydrofolate from dihydrofolate through the inhibition of dihydrofolate reductase . Methotrexate utilizes several intercellular pathways to antagonize folate which results in profound effects on rapidly divi... |
Recent european union statistics revealed that the united kingdom has more obese women (24%) than any other member state . Overweight and obesity was responsible for 7.3% of morbidity and mortality in the united kingdom in 2002 and contributed an estimated 3 billion in direct health costs to the national health service... |
The data presented here are from a pilot study conducted by the studies to treat or prevent pediatric type 2 diabetes (stopp - t2d) prevention study group . Stopp - t2d prevention is a national institute of diabetes and digestive and kidney diseases multisite study designed to reduce the prevalence of risk factors for ... |
World illiteracy map closely coincides with the world poverty map, where malnutrition and other unhealthy conditions prevail . It was documented that those subjects who are better educated, wealthier, and live in better circumstances have better health status, with a greater frequency of dental visits than those who ar... |
Cervicogenic headache, first described by sjaastad (1), is characterized as unilateral fronto - temporal headache with clinical symptomatology similar to migraine (1, 2). Useful clinical diagnostic criteria were published in 1990 (3) and revised in 1998 (4). However, the concept of cervicogenic headache is not universa... |
Breast cancer is the second most common cancer worldwide and, although treatments have improved greatly over the last decade, this cancer remains the leading cause of cancer - related death in women.1 therefore, there is a huge need to identify novel molecular targets in breast cancer . 3-phosphoinositide - dependent k... |
Graphene is a new class of material that is intensively studied, which points to its remarkable physical properties . Today, graphene is presented as a promising material for the observation of novel quantum phenomena and for the development of next - generation electronic and photonic nanodevices.1,2 recent applicatio... |
The primary culture of fetal rat cortical neurons is widely used in cell models of many neurological disorders . However, owing to the complicated procedures involved in dissection and culture, a universally accepted protocol for their derivation has not yet been determined . Diverse techniques make it difficult to rea... |
The protective role of zinc in cerebral ischemia has been clearly sustained [13]. Several studies have shown that the ischemic preconditioning and postconditioning decrease intracellular zinc accumulation in a gerbil model of oxygen - glucose deprivation, thus causing ischemic tolerance [4, 5]. Interestingly, an increa... |
Nippon data (national integrated project for prospective observation of noncommunicable disease and its trends in the aged) is a cohort study of participants in the national survey on circulatory disorders of japan, which has been conducted by the ministry of health, labor and welfare of japan . Nippon data includes tw... |
Recent advances in nanoscience and nanotechnology offer opportunities for the development of innovative and promising applications in fields ranging from electronics to the food industry and medicine . Expectations for nanomedicine applications are high, and research targeting numerous applications for nanocarriers, su... |
Chronic renal failure (crf) progresses relentlessly to end - stage renal disease (esrd). In patients with advanced crf, the disease tends to progress faster than in those with mild to moderate crf [1, 2]. Although several factors, such as advanced age, hypertension, dehydration, and the use of drugs, are known to affec... |
Almost 100 trillion symbiotic microbes inhabit a single human body which is almost 10 times the number of cells present in an adult human . Microbiome was first used by joshua lederberg3 for the ecological community of commensal, symbiotic, and pathogenic microorganisms that literally share the human body . He suggeste... |
Healthcare systems, including those in prosperous and developed countries, are increasingly faced with huge challenges . With emerging needs vital for health reform, different approaches have been used to start programs in many countries . Underpinning these approaches is the role of the client, and his / her increased... |
There are several types of removable and fixed functional appliances for the correction of class ii division 1 malocclusions with mandibular deficiency in order to stimulate mandibular growth by forward positioning the mandible . The selection of the appliance varies according to the clinicians preference, type of the ... |
Blastocystis has been associated with human gastrointestinal disease in both immunocompromised and immunocompetent hosts [1, 2]. Clinical features due to infection by this protozoan include acute or chronic diarrhea, sometimes self - limited, and could be accompanied by abdominal pain, tenesmus, pruritus, anorexia, nau... |
Leptin is an adipokine, produced in proportion to white adipose tissue mass, which is critical for metabolic homeostasis . Deficiency in either leptin or its receptor, lepr, leads to obesity due to increased feeding (alingh prins et al ., 1986; mclaughlin and baile, 1981) and reduced energy expenditure (through a decre... |
Canrenone (cr), a cardiovascular drug, a sort of steroid, is spironolactone's major metabolite and has been widely used as a nonselective aldosterone receptor antagonist clinically to treat heart failure, high blood pressure, edema, liver ascites, and other cardiovascular diseases [1, 2]. However, canrenone also has th... |
Paget's disease of bone is a chronic bone remodeling disorder featuring one or more areas of aggressive osteoclast - mediated bone resorption, followed by imperfect osteoblast - mediated bone repair . The disease is frequently recognized because of elevation in serum alkaline phosphatase levels, which reflects both the... |
The physical map and dna sequence derived from the human genome project revolutionized cytogenetic testing by providing the ability to detect submicroscopic imbalances across the genome . Technologic advances, namely the advent of comparative genomic hybridization, allowed for the detection of cnvs in the research sett... |
(crp) and erythrocyte sedimentation rate (esr) are the routinely requested tests[14]. Others include acute phase proteins such as fibrinogen, which together with esr are factors that are strongly associated with whole blood viscosity (wbv). Wbv is one of virchow's triad, which has been an established concept of three p... |
Partial anomalous pulmonary venous drainage (papvd) is a developmental anomaly of the cardiovascular system, the cause of which can be sought both in the abnormal gene structure, as well as in environmental factors . The essence of the defect seems to be the persistence of the early - stage embryo connections between t... |
Halitosis, oral malodor, fetor oris, or bad breath are the common terms which are used to depict obnoxious breath emitted from a person s mouth, in spite of whether the malodorous substances in the breath are derived from oral or non - oral sources, and it can have major detrimental impact on normal social interactions... |
Depression is a universal disorder, and among most cultures, there are high rates of both its presence at current point and throughout the whole life (hammen 2006). World health organization (who) states that depression is a leading mental disorder from which suffer europeans and especially women . In poland, half of t... |
Mesenchymal stem cells (mscs) are highly sensitive to environmental cues, including nanoscale topographical features, and changes in the feature height and extent of disorder of the features have been shown to modulate stem cell fate . Osteogenic nanotopographies would have great potential for use in patterning implant... |
One of the most common problems found in the occupational health sector is unfavorable climate conditions in workplaces, in other words, working in hot environments . In addition to the reduction in human's work capacity, hot workplaces can induce various diseases in human including thermal strain . Heat also considers... |
In cases of prostate carcinoma, pulmonary metastases are the next most common metastases after bone metastases, but clinically, the presence of pulmonary metastases without other metastases is rare . The present report describes a rare case of prostate carcinoma with pulmonary metastases alone in a man who was admitted... |
Osteoporosis occurs when bone strength deteriorates due to decreases in bone mineral content (bmc) and bone mineral density (bmd), the most basic markers of bone metabolism, as well as changes in bone microarchitecture, all of which occur with aging1 . In particular, osteoporotic fractures occur most frequently in the ... |
Blastomycosis is a common enzootic systemic mycosis in dogs which are much more susceptible to disseminated infection than humans . Infection during pregnancy has occasionally been reported in women, with immunosuppression associated with pregnancy possibly playing a role in susceptibility [213]. Systemic infection has... |
Frontal cortex (fc) and cardiovascular functions are reciprocally connected, as part of the model of neurovisceral integration . Compared with vehicle - treated spontaneously hypertensive rats (shrs), we recently reported an inverted bilateral behavior of angiotensinase activities between left / right fc and plasma aft... |
Dislocation is one of the severe instabilities in the wrist bones; this type of injury is not very common but its proper management is crucial (1). A few number of patients admitted to the emergency department (ed) due to the upper extremities trauma suffer from the wrist bones dislocation that their complain is pain a... |
In the current practice of periodontics, clinicians are faced with the challenge of not only addressing biological and functional problems present in the periodontium, but also providing therapy that result in acceptable esthetics . The presence of mucogingival problems and gingival recession around anterior, highly vi... |
Use of radiotherapy with or without chemotherapy as primary treatment for cancer of the head and neck has increased over the past decades . Although the primary goal of treatment is to cure, a perceived additional benefit is the preservation of the organs of the head and neck . Thus, swallowing function after treatment... |
Mazabraud syndrome is rare benign disorder defined as combination of monostotic or polyostotic fibrous dysplasia with single or multiple intramuscular myxomas . Fibrous dysplasia developed in bone is a benign and fibro osseous lesion, and myxomas presented as benign mesenchymal tumors.1 the first case was reported by m... |
Hearing impairment, as a partial decrease in the ability to detect sounds, can be the consequence of sensorineural malfunctions of the ear . Prolonged exposure to high levels of noise can cause sensorineural hearing loss especially in a noisy workplace . Noise - induced hearing loss (nihl) as one of the most common typ... |
The suprascapular nerve receives fibers from c5 and c6 nerve roots with an occasional contribution from the c4 root . Therefore, radiculopathy of these sources must be ruled out in cases of suspected suprascapular nerve entrapment . The suprascapular nerve provides motor innervation to the supraspinatus and infraspinat... |
Many pregnant women around the world eat diets that are nutritionally inadequate, and result in undernourished infants who are at greater risk for health problems later in life . Infants should be exclusively breastfed for the first six months of life to achieve optimal growth, development and health . Thereafter, to m... |
The purpose of this study is to compare the effects of the two clutches on recording the condylar movement . Ten subjects (6 women, 4 men; mean age 25.4 years) participated in the study . The mandibular movement, sagittal condylar inclination angle, and transversal condylar inclination angle of each subject were record... |
Erlotinib is a class of the newly named targeted therapies, designed to inhibit the epidermal growth factor receptor (egfr) (figure 1). The small molecule was designed to bind to the atp pocket of the intracellular tyrosine kinase domain of the egfr, inhibiting the phosphorylation and thereby blocking the initiation of... |
Cocaine addiction is a chronic relapsing disorder characterized by loss of control over drug - seeking . A major challenge in the successful treatment of cocaine addiction is the risk of relapse, which remains high even after months or years of abstinence [1, 2]. Animal models of relapse are essential for elucidating t... |
Generation of the kcne2 allele (hereafter referred to as kcne2) was performed as part of the european conditional mouse mutagenesis program and knockout mouse project (eucomm / komp) projects and sanger mouse genetics project . Mice were generated from embryonic stem cell clone epd0156_2_f10 and backcrossed to c57bl/6n... |
This study was based on swedish national registers held by the national board of health and welfare and statistics sweden . This identification number was used to link information from different register sources after the study had been approved by the regional ethics committee in stockholm . All individuals born in 19... |
Protein - protein interactions are the basis for most cellular processes, including signalling, protein synthesis, and metabolism . Detailed knowledge of these protein networks is required in order to better understand diseases and develop adequate treatments . At present, protein - protein interactions are commonly in... |
, ktrzy przeszli zabiegi kardiochirurgiczne w latach 19992009 . Odnotowywano okoooperacyjne uycie wosku kostnego, dane okoooperacyjne oraz parametry wynikw . Wykonano wielowymiarow analiz regresji logistycznej, aby zdefiniowa niezalene czynniki ryzyka dla pooperacyjnego rozejcia mostka . Wystpio ono u 1,4% pacjentw, u ... |
Stem cell - based therapies for neurological disorders are rapidly moving toward clinical trials (steinbeck and studer, 2015). One major task en route to the clinic is to generate standardized gmp - grade human pluripotent stem cell (hpsc)-derived neural progenitors that will mature and function in the adult brain afte... |
The major physiologic action of insulin is to instruct tissues in the assimilation of dietary macronutrients and activate anabolic pathways that support growth and repair of tissues during the fed state . The actions of insulin on specific tissues vary depending both on the role that tissue plays in the assimilation of... |
Acute epidural hemorrhage (edh) represents one of the most urgent neurosurgical lesions, and most frequently occur as a result of skull fracture with subsequent damage to the middle meningeal artery (mma). In most cases, arterial bleeding focus could be identified and controlled in an open surgical field . On the other... |
Inflammatory bowel diseases (ibd), comprising of crohn's disease (cd) and ulcerative colitis (uc), are chronically remittent and progressive inflammatory disorders occurring in gastrointestinal tract [13], characterized by intestinal mucosal inflammation culminating in abdominal pain, recurrent diarrhea, blood stools, ... |
In the past decade or so, the remarkable advancement of dna sequencing technology and application has led to an astronomical accumulation of genomic data . This is especially true for the prokaryotic genomes as individual of them is only a few megabases in size . It is expected that in the next decade or two, there wil... |
Cisplatin and related platinum - based therapeutics are used widely in the treatment of a variety of cancers . However, the clinical use of cisplatin can be complicated by myelotoxicity, ototoxicity, nausea and vomiting, and nephrotoxicity . Nephrotoxicity secondary to cisplatin administration is dose - dependent, and ... |
Complicated grief (cg) is a disorder of significant impact, as described in other articles in the current issue . An important question with which psychiatrists, researchers, the dsm-5 committee, and the general public have wrestled is how to address the unique suffering of those with cg, and how to distinguish it from... |
This disease is named after thomas addison, who first described patients affected by this disorder in 1855, in the book titled on the constitutional and local effects of the disease of supra renal capsule . Addison's disease can present as a life - threatening crisis, because it is frequently unrecognized in its early ... |
Hepatocellular carcinoma (hcc) is the second - commonest cause of cancer - related death, and accounted for 746,000 world deaths in 2012 . Hcc is the fifth - commonest cancer in men and the ninth - commonest cancer in women, accounting for 782,000 new cases in 2012.1 male sex and advancing age are common predisposing d... |
Internal hernia is the protrusion of the intra - abdominal viscera through peritoneal or mesenteric orifices within the peritoneal cavity . Internal hernias is an infrequent cause of small bowel obstruction with a reported incidence of up to 5.8% of intestinal obstruction, and paraduodenal hernias representing 50% of t... |
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