text stringlengths 0 868k |
|---|
Stem cells derived from adult human tissues are of great scientific interest to provide potential individual cell - based therapy without ethical and immunological problems associated with human embryonic stem cells . Testicular tissue retrieved in the assisted reproduction programme might be an important source of ste... |
Chagas disease, or american trypanosomiasis, is caused by the protozoan parasite trypanosoma cruzi . Chagas disease is primarily a vector disease endemic in 21 latin american countries, where it has a strong economic impact because it primarily affects economically active people . Approximately 10 million people are in... |
Ghrelin is a 28-amino acid motilin - related peptide hormone mainly secreted by the x / a - like enteroendocrine cells of the oxyntic (parietal) mucosa of the gastric fundus . It is the endogenous ligand for the growth - hormone secretagogue receptor (ghs - r) 1a, recently discovered by two independent research groups ... |
Over the past decade the incidence of hepatocellular carcinoma (hcc) has doubled . In the asia - pacific region, 500 000 new cases occurred every year, with an estimated 360 000 deaths in far east countries only . China alone had more than 60% of the total hcc cases, most of which were due to chronic hepatitis b virus ... |
Mice were handled according to guidelines established by the northwestern university animal care and use committee, the national institutes of health and the society for neuroscience . Midbrain slices were visualized using infrared - differential interference contrast (ir - dic) video microscopy system (for patch clamp... |
Management of patient with prolactinoma during pregnancy is a big challenge to the obstetrician as prolactin levels elevation in pregnancy is a normal phenomenon and there are possibilities that one can misdiagnose this problem . Although the drug cabergoline has almost completely replaced bromocriptine in nonpregnant ... |
The discovery of mirror neurons that fire when an animal performs a goal - directed action or sees others perform the action gave rise to both monkey and human studies on the neural correlates of imitation (rizzolatti and craighero, 2004; iacoboni and dapretto, 2006). While the circuitry for motor imitation is describe... |
Obesity is characterized by an excessive accumulation of fat in the adipose tissue (1, 2). A product of the obese (ob) gene, called leptin, is released primarily from adipocytes and plays a key role in regulating body weight (3). In most obese subjects, leptin fails to perform its physiological functions in spite of it... |
The health risk assessment of environmental selenium, concerning both abnormally low and high intakes, and the related regulatory guidelines are generally based on old evidence, since they have generally been unable to take into consideration the most recent epidemiologic and biochemical evidence, and particularly the ... |
The occurrence of end - stage renal disease (esrd) and dialysis access placement in the united states continues to increase . Due to the superior long - term patency, lower complications, and decreased mortality rates, arteriovenous fistulas (avfs) are the access of choice and represent 41.3% of the total hemodialysis ... |
Essential thrombocythemia (et) is one of the bcr - abl negative myeloproliferative neoplasms . Diagnosis is made when 1) platelet count is higher than 450 10/; 2) patients have the jak2 v617f mutation or another clonal mutation such as in the gene encoding the thrombopoietin receptor (mpl); 3) bone marrow reveals megak... |
Traumatic brain injury (tbi) is a global public health issue with few treatment options available (chauhan, 2014). With approximately 10 million people affected by tbi annually, it is a major cause of death and disability worldwide, and the world health organization projects that it will surpass the mortality and morbi... |
Internally, mutations and shifting genetic backgrounds change the genetic context in which genes are expressed . Externally, changing environmental conditions alter the global context within which molecular systems operate and to which they must respond . Understanding how biological systems evolve robust function acro... |
Diabetes mellitus is a syndrome of disordered metabolism with inappropriate hyperglycemia due to either an absolute or relative deficiency of insulin secretion or a reduction in the biologic effectiveness of insulin (or both) and is associated with disturbances in the metabolism of carbohydrates, protein, and lipids . ... |
Sharp objects such as a toothpick sometimes fail to pass and may cause a perforation . The possible complications reported in the literature include obstruction, perforation, haemorrhage, fistula formation and sepsis . Toothpick injury to the gut is a rare condition for which a low intellectual quotient and extremes of... |
The problems get compounded when there is the presence of infection around the hip implants.1 deep infection after a hip fracture operation impairs functional outcome and increases mortality by 10.4%.2 eradication of infection becomes necessary for any definitive procedure to be performed on the hip . The patients are ... |
Previous randomized clinical trials have established the efficacy of reducing intraocular pressure (iop) in patients with glaucoma,15 confirming that iop management plays a central role in preventing further progression of glaucomatous optic neuropathy.68 although the goldmann applanation tonometer (gat) (haag streit, ... |
Congenital cholesteatomas of the temporal bone are epidermoid cysts of embryologic origin that result in progressive desquamation and trapping of squamous epithelium behind an intact tympanic membrane.1 they are benign, slowly progressive lesions that can be found in various areas of the temporal bone.1 we report a cas... |
Ir injury not only exacerbates the damage of the local ischemic tissues, but also causes remote organ injury or even multiple organ dysfunction syndromes (2 - 4). The pathogenesis of ir injury is complex and multifactorial, involving an intrinsic intracellular injury process during the ischemic phase and an induced inf... |
In april 2006, a 76-year - old man was admitted to the emergency department of pontchaillou university hospital, rennes, france, with acute onset of fever, lumbar pain, and dyspnea . (90.6% neutrophils), c - reactive protein 216 mg / l (normal value <5 mg / l), and arterial oxygen partial pressure 67 mm hg (room air). ... |
Periodontitis, a periodontal disease, results from interaction between the immune system and oral bacteria that may promote oxidative stress and initiate an inflammatory cascade inducing the destruction of the oral structure . The immunomicrobial pathogenesis of periodontitis involves chronic inflammation, which alters... |
Various types of cages are currently widely used for the treatment of degenerative cervical disc disease . However, controversy remains regarding a high incidence of complications, such as cage subsidence, kyphotic deformity, and pseudarthrosis [13]. Anterior cervical discectomy and fusion (acdf) with plate fixation ha... |
Occupational exposure to hair dyes has been associated with an increased risk of bladder cancer [1, 2]. The international agency for research on cancer (iarc) concludes that hairdressers and barbers are probably at greater risk of bladder cancer because of their exposure to hair dyes . This has raised concerns that per... |
The first - generation fluoroquinolones (e.g., ciprofloxacin, ofloxacin, norfloxacin) are primarily active against gram - negative and some gram - positive organisms . The second - generation fluoroquinolone, levofloxacin, is the l - isomer of ofloxacin and demonstrates somewhat improved gram - positive activity . Howe... |
The first outbreak we investigated occurred in a facility that provided housing and harm - reduction services to a predominantly hiv - positive, homeless, and drug - using population (site a). The first tb case - patient identified was a 53-year - old hiv - positive man residing there, in whom pulmonary tb was diagnose... |
Age - related macular degeneration (amd) is the most common cause of severe vision loss in patients over the age of 60 . There are two major forms of amd, a non - neovascular or atrophic and a neovascular form . The neovascular form (nvamd) is characterized by the formation of subretinal choroidal neovascularization (c... |
The differences between definitions of health can be understood as caused by differences in ontological assumptions about the nature of reality and by the view of the nature of human beings (tengland, 2007). The biomedical view of reality and of health is built on the positivistic ideal of science, which prioritises wh... |
50100 million cases of dengue infections with 500000 cases of dengue hemorrhagic fever (dhf) and 22,000 deaths occur annually in the world (who 2011). In asian countries, dhf is a leading cause of serious illness and death among children (who 2011) and case fatality rates vary between 0.5 and 3.5% . Dengue fever (df) h... |
Avian influenza viruses (aivs) are member of the family orthomyxoviridae, genus influenzavirus a . Influenza a viruses are classified according to the antigenic properties of their hemagglutinin (ha) and neuraminidase (na) surface glycoproteins . Till date, 16 ha subtypes and 9 na subtypes have been recognized [2, 3]. ... |
Tanzania is located on the eastern coast of africa and consists of the tanzanian mainland and the island of zanzibar . Countries neighboring tanzania include, counterclockwise from the north, kenya, uganda, rwanda, burundi, the democratic republic of congo (drc), zambia, malawi, and mozambique . In kenya and uganda, pp... |
Sebaceous hyperplasia (sh) is a benign proliferation of the sebaceous glands, which in most cases is idiopathic and affects elderly patients . Sh results from intrinsic, genetically determined (chronological) aging and extrinsic environmental photoaging . Moreover, this affection can arise in the setting of genetic dis... |
The basque department of health released in 2010 the strategy for tackling the challenge of chronicity in the basque country . One of its five priority policies is contributing to the continuity of care for chronic patients . A key strategic project is the development of new integration initiatives and pilots projects ... |
Chronic obstructive pulmonary disease (copd) is one of the most frequent causes of mortality in the world . Copd is usually associated with a number of secondary impairments such as cardiac, metabolic, peripheral muscle, and psychosocial dysfunction . A major problem among these co - morbidities is skeletal muscle dysf... |
Trigeminal neuralgia (tn), a neuropathic disorder of one or both of the trigeminal nerves, occurs most often in people over age 50, and affects women more often than men . Tn can be either primary trigeminal neuralgia or secondary trigeminal neuralgia, which is associated with some other diseases, with symptoms such as... |
The patient is a 54-year - old male who was referred to our clinic due to a large abdominal mass . He complained of early satiety, anorexia, weakness and weight loss during the 6 months before admission . Nine years ago, he had noticed the presence of a 4- to 5-cm right renal mass . He was advised to have surgery but d... |
In recent years, advances in the training of military and aviation personnel have been successfully applied to the training of health care providers in efforts to enhance patient safety . These include simulation to teach judgment and technical skills and a systems perspective in the analysis of errors and near misses ... |
Hormonal changes at the moment of parturition may constitute an important regulatory mechanism for myometrial contraction . In some species (e.g., sheep), sudden changes in circulating cortisol, oestrogen, and progesterone appear to be important factors for the onset of labour, whereas in humans, these signs remain unk... |
Bacterial strains and media - s. sonnei strains, named ss9 and ss12, were isolated from children with acute diarrhoea who presented for treatment at children's hospital joo paulo ii / hospital foundation of the state of minas gerais, belo horizonte, brazil . The isolates were selected as producer and indicator strains ... |
Cardiovascular prevention and rehabilitation improves functional and clinical status, health - related quality of life, and prognosis in patients with coronary heart disease (chd) recovering from acute events and invasive interventions.1 for more than a decade, cardiac rehabilitation (cr) has been recommended for chd a... |
From april to september 2004, using cluster random sampling method, 3600 subjects were enrolled based on postal code divisions of 17 districts in shiraz, southern iran . Each subject was invited to refer to mottahari clinic of gastroenterohepatology research center affiliated to shiraz university of medical sciences . ... |
Poly (methyl methacrylate) resins have dominated the denture base market for over 50 years . It is known that denture bases may act as a reservoir of microorganisms and contribute to oral diseases, such as denture stomatitis, a chronic inflammatory response in the oral mucosa, in complete denture wearers . It has a mul... |
Mitochondria contain their own genome and, as is the case for any other genome, must maintain tight control over the expression of their encoded gene products . Mitochondrial genes typically encode either components of the respiratory chain for atp synthesis or the mitochondrial translation machinery . Regulating the e... |
Smoking is an important risk factor for oral diseases such as oral cancer, periodontal disease, cleft lip, cleft palate, alveolar bone loss, and black hairy tongue.1 - 3 the evidence showing that the use of tobacco is the major risk factor for oral cancer and potentially malignant lesions of the mouth is obvious.4 ciga... |
Fibromyalgia syndrome (fms), which is characterized by widespread pain and fatigue, is a disease that affects the connective tissues and locomotor system1,2,3 . Patients with fms also suffer from weakness, fatigue, lack of energy, sleep disturbances, waking up tired in the morning (non - restorative sleep), and stiffne... |
This study is approved by institutional review board of hanyang university guri hispital (no . 2012 - 003) on human subjects research and ethics committees . For this retrospective cohort study, we initially enrolled 339 patients who underwent less than two - level posterior instrumented fusions for lumbar spinal steno... |
" medical studies prepare [students] well for the examinations, but poorly for the job as a doctor " concluded a poll of the centre for the development of higher education (zentrums fr hochschulentwicklung) among approximately 300 medical students in germany [http://www.che.de/downloads/medizinstudium20_auswertung_befr... |
Stainless steel crowns have long been used as durable restorations for the reconstruction of primary teeth that have undergone pulpotomy or pulpectomy and those with developmental defects or extensive, multi - surface carious lesions . These crowns can maintain the health of the surrounding tissues and prevent developm... |
More than 365 million people are estimated to have t2 dm, and almost 300 million people have major depression . Both these disorders are projected to be among the five leading causes of disease burden by 2030 . Depression can be viewed as a modifiable independent risk factor for the development of t2 dm and for progres... |
Achromobacter xylosoxidans (ax) is a non - fermentative aerobic gram - negative bacillus . The emergency brain computer tomography (ct) scan did not reveal any anomaly . In his medical history, there was an auditory injury due to a cranial trauma incurred in a skiing accident 60 years earlier . Cytobiochemical analysis... |
Neisseria gonorrhoeae (ngo) or gonococcus, a gram - negative diplococcus, is the etiological agent of the sexually transmitted bacterial infection (sti) gonorrhoea . Gonorrhea is the second most frequent sti worldwide, where the total number of new cases of gonorrhea in adults was estimated to be 106.1 million cases ou... |
Staphylococcus aureus and its resistant form, methicillin - resistant s. aureus (mrsa), rank top among the clinically most relevant nosocomial pathogens, leading to increased morbidity, mortality, length of hospital stay and costs [14]. Colonized healthcare workers (hcws) are capable of developing clinical s. aureus in... |
Adult onset asthma with periorbital granuloma (aapox) syndrome was first described in 1993 by jakobiec et al and is considered to be a periorbital disease with a specific granulomatous inflammation . Palpebral biopsy shows multinucleated histiocytes with a foamy cytoplasm, referred to as touton giant cells . In a recen... |
Breast cancer imaging has improved over the last decade with higher and more uniform quality standards for mammography as well as through the increasing use of sonography and magnetic resonance imaging as the adjunct tools . Mammography is still the only screening tool to detect breast cancer for asymptomatic women . D... |
Anopheles gambiae is the main vector of the human malaria parasite, plasmodium falciparum, in africa . The number of cases of malaria, and their severity, have increased, leading to an increase in the social and economic burden of this disease . The development of drug resistance in parasites and insecticide resistance... |
Continuity of care is the process by which patients experience linked care from one health care setting to another . It has been defined as having three components: (1) physician continuity, (2) information continuity, and (3) management continuity . 1 previous studies have consistently demonstrated deficiencies in eac... |
Breast cancer is the most common cancer in women worldwide, affecting approximately 240,000 cases in north america . Lung, bone, and brain are common sites of metastasis in patients with breast cancer . Mediastinal lymph node (ln) metastases, however, occur in only 2% of patients with breast cancer during surveillance ... |
We denote by [a, b] = ab ba the simple commutator of the elements a, b r and by [a, b]k = [[a, b]k1, b], for k> 1, the kth commutator of a, b. throught this paper we will use the following notation: u will be the (two - sided) utumi quotient ring of a ring r (sometimes, as in, u is called the symmetric ring of quotient... |
Hypothyroidism can affect all the organ systems of the body and can have varied manifestations . It can lead to hyperprolactinemia mainly because of pituitary thyrotroph hyperplasia . In hashimoto's thyroiditis, the incidence of hyperprolactinemia has been reported to be 11.1% in subclinical and 42.4% in overt hypothyr... |
Nanotechnology has been used in various fields of science and technology, including physics, electronics, medicine, and chemistry, among other areas of interest to the scientific community . Interest in nanotechnology is growing and continues to change the way we perceive and execute things, has a pronounced effect on ... |
Oral hygiene can vary in children within the same age group and depends on many factors, one of the most important of which are the hygiene habits of adults and the steps they take to pass on these habits to those in their care . Being aware of the need to take care of oral health is reflected in the frequency with whi... |
Granulomas in the gallbladder wall are exceedingly rare . A case of granulomatous cholecystitis in the context of tuberculosis we report a case of gallbladder epithelioid and giant cell granulomas occurring in the course of treated thoraco - abdominal sarcoidosis and revealed by lithiasic cholecystitis . The patient (m... |
It has excellent tissue penetration in the skin and soft tissue infections and is a well - tolerated drug . Cutaneous adverse drug reactions (adrs) are seen in about 12% of treated patients . Urticaria angioedema, maculopapular exanthem, and photosensitivity are the most frequently documented cutaneous adverse reaction... |
Spinal cord injury (sci) is one of the most serious injuries of the central nervous system, resulting in severe disabilities that affect independent functional activities in the individual s personal and social life1, 2 . Most individuals with sci generally rely on assistive technology (at) as the primary means of acco... |
Being at risk of undernutrition or being undernourished is a frequent problem among older patients,13 but to a less extent among older home - dwelling people.46 however, older home - dwelling people receiving home health care have been found to be at high risk for developing undernutrition.7 therefore, to use a nutriti... |
Maternal thyroid function changes during pregnancy as a result of physiological alterations in some factors such as thyrotrophic effect of human chorionic gonadotropin (hcg), increased iodine clearance in the kidneys, and increased thyroid hormone - binding globulin (tbg) concentration . Thyroid dysfunction, including ... |
The antifolate combination sulfadoxine /pyrimethamine (sp) is currently the first line treatment for uncomplicated falciparum malaria in several african countries . Pyrimethamine (pm) and sulfadoxine (sd) are inhibitors of dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) respectively . The selection a... |
A segmental testicular infarction (sti) is a rare cause of acute scrotum . The etiologic mechanism is largely considered idiopathic, but cases have been associated with hypercoagulability disorders, vasculitis, torsion, trauma, infection, and iatrogenic vascular injury (1, 2). A sti usually presents with acute scrotal ... |
The diabetes autoimmunity study in the young (daisy) has followed two cohorts of young children at increased risk of diabetes (n = 2,542), including relatives and general population children screened for susceptibility hla - dr / dq genotypes . Autoantibodies to gad, ia-2, and insulin (iaa) were measured in all samples... |
Allotransplantation is currently viewed as the preferred solution for the treatment of end - stage organ failure . However, only a small percentage of those patients who could benefit from this therapy receive it due to a shortage of donor organs . This shortage of donors has stimulated interest in the possible use of ... |
The prerequisites for good adhesion of the composite resin to the tooth structure, is that the adherent surfaces be clean and compatible, which is often difficult to attain and maintain . As the tooth surface is altered by rotary and manual instrumentation during cavity preparation, the smear layer is generated . Howev... |
The 2009 pandemic influenza a virus (h1n1; hereafter, h1n1 2009) was reported for the first time in mexico in april 2009 and subsequently spread globally . The virulence of the h1n1 2009 virus was not higher than that of seasonal influenza viruses, but the h1n1 2009 virus had higher transmissibility . For this reason, ... |
Tongue diagnosis is one of the important contents of four diagnoses in traditional chinese medicine (tcm). The four diagnoses means observation, listening, interrogation, and pulse - taking . Traditional tongue diagnoses depend on observations of tongue features such as color, shape, moisture, and texture by tcm doctor... |
Bipolar affective disorder (bpad) is a major psychiatric problem with multifactorial etiology affecting approximately 1% of population and with all other bipolar spectrum disorders the prevalence will be as high as 5% . Bipolar disorder is the sixth leading cause of medical disability world - wide among people 15 - 44 ... |
This work has been supported by fundaci la marat de tv3 with grant #20131210 and instituto de salud carlos iii - feder with grant #pi13/00448 |
Chromium, though a micronutrient naturally present, can lead to life threatening complications when ingested in high levels . It is a rare poison and is associated with life threatening complications involving various organ systems . R, a 21-year - old gentleman from south india, who worked in a cellphone shop, was bro... |
The four chemicals (purity 98%), and tcdd, 98% (cambridge isotopes laboratories inc ., andover, ma, usa) were dissolved in dimethyl sulfoxide (dmso) (bdh laboratory supplies, pool, uk). Louis, mo, usa) was dissolved in 96% ethanol (extra pure; merck, darmstadt germany). Luciferin and fluorescamine were from amersham ph... |
They are usually small, quite round and noncompressive3). Magnetic resonance imaging (mri) cranial mri showed a left - sided choroidal fissure cyst measuring 45 mm (fig . The cyst was hemorrhagic and showed fluid - fluid level on t2-weighted and susceptibility weighted images . She was followed conservatively . During ... |
Emphysematous pyelonephritis, a less frequently noticed acute clinical condition, is invariably associated with uncontrolled diabetes or immune suppression . Infective renal mass with gas lucencies is the hall mark with associated pyrexial and septic state . Asymptomatic incidental detection of the condition during fol... |
Karen lawson, md, abihm, an assistant professor of university of minnesota's family medicine and community health, is director of integrative health coaching at the center for spirituality & healing (www.csh.umn.edu). She is a physician, board - certified in both family medicine and integrative and holistic medicine . ... |
Implementation of the national and international asthma guidelines has been shown to lower emergency health care resource utilization while improving patient outcomes (bateman et al 2001, 2002). However, several barriers continue to slow the implementation of asthma guidelines into daily primary care practice (cabana e... |
Genetic predisposition, androgens, and aging are closely related to aga, but pathogenesis has not been clarified yet . Dermal papilla is considered a key element in aga development and thickening and hyperplasia of the dermal sheath is the only universally accepted histopathological evidence in aga . Both dermal papill... |
Anesthetic management of patients with severe malformations of the skeletal system can be very challenging due to altered anatomy and physiology.1 here, we report a case of ultrasound - guided epidural block in combination with low - dose ketamine during cesarean section on a patient with severe malformations of the sk... |
Until 2006, only 100 cases had been reported in the world literature of akc, the nevoid and the rarest of the five varieties of angiokeratomas . It is confirmed histopathologically by hyperkeratosis, papillomatosis, and acanthosis with its vascular proliferation restricted to the papillary dermis, the latter differenti... |
Cerebral amyloid angiopathy (caa) is the deposition of amyloid proteins in the cerebrovasculature . Caa is a well - known and relatively common etiology for intracerebral hemorrhage (ich), with a predilection for the meningocortical vasculature . In the elderly while caa is a relatively frequent cause of ich, large syn... |
Type 1 diabetes mellitus (iddm) results from autoimmune destruction of insulin producing beta cells and is characterized by the presence of insulitis and beta cell auto antibodies . It is associated with other autoimmune endocrine disorders and auto antibodies leading to the development of autoimmune polyglandular synd... |
Merkel cell carcinoma (mcc) is an uncommon cutaneous malignancy with an estimated 1,500 cases diagnosed annually in the us . It is most commonly seen in men in their 70s and on sun - exposed skin . Moreover, when it is found in immunosuppressed patients, the clinical course can be more fulminant . The cell of origin re... |
Only 10% of cases are due to an inherited predisposition, while the majority are attributable to alterations in brca1 and brca2, which present the strongest risk factors for breast and ovarian cancers . Indeed, studies of lifetime risk of ovarian cancer have revealed that it ranges from 39% to 54% in women identified a... |
The use of whole body vibration (wbv) has become an increasingly popular method of training for enhancing performance in sport . Significant improvements in performance have been demonstrated across a wide spectrum of sporting activities with the use of wbv training . The most common improvements are seen in explosive ... |
The planar cell polarity (pcp) pathway maintains cell polarity in the plane of epithelial tissues in drosophila melanogaster embryos through the complex interplay of several core molecular components, including frizzled, dishevelled, strabismus (stbm), and prickle (tree et al ., 2002). The same proteins also regulate p... |
Dyadic, traditional senior to junior mentorship, relationships have been shown to have both career and psychosocial functions and usually proceed through several stages before often concluding . Peer or collaborative mentorship relationships, a partnership with members of the same approximate age and/or career stage, a... |
Eradication of hiv-1 from active and latent reservoirs and achieving a functional cure, defined as long - term undetectable viraemia for an as - yet - undefined period (probably several years) in the absence of art, is currently a high priority area for the aids research community and the national institutes of health ... |
Test materials: diflubenzuron an acylurea compound (n-[(4-chlorophenyl) amino] carbonyl]-2, 6-difluorobenzamide) acts as a chitin synthesis inhibitor and is also known as dimilin. Three formulations of dimilin, 25 per cent wp, 2 per cent gr and 2 per cent dt were supplied by whopes / who, geneva, switzerland (manufactu... |
Cancer of cowper's gland is a rare cancer with fewer than 10 recorded cases [1, 2, 3, 4, 5, 6]. The literature is composed of case reports, primarily predating the modern era of chemotherapy . The reported cases of cowper's gland carcinoma have all been adenoid cystic carcinoma (adcc), and treatment effective against a... |
The elbow s susceptibility for stiffness has been described before and multiple factors have been implicated [1, 2]. When conservative measures fail, a surgical approach might be indicated . The functional rom has been described by morrey as minimum extension of 30 and flexion up to 130. in particular cases even minor ... |
Achieving optimal femoral component rotational alignment in total knee arthroplasty (tka) is crucial in establishing a balanced knee reconstruction and ensuring adequate patello - femoral tracking.110 unbalanced knees can lead to instability, patellofemoral problems, persistent pain, stiffness, and generally poorer out... |
The interplay between the gut, the normal microbiota and gut pathogens has received particular attention in recent years (for review see refs . 1 - 3), however, many aspects still need to be investigated . For instance, it is of interest to identify bacterial genes, which are specifically expressed in the gut environme... |
Diabetes mellitus (dm) is one of the most challenging and burdensome chronic diseases of the 21st century.dm currently affects about 285 million adults worldwide and it is expected to rise to over 400 million adults by 2030.diabetes mellitus type 2 is responsible for over 90% of all cases of diabetes . Most new patient... |
The organization and remodeling of the actin cytoskeleton are controlled by the rho family of small gtpases, which includes rho, rac, and cdc42 . These proteins have been implicated in the formation of stress fibers, lamellipodia, and filopodia, respectively (reviewed in hall 1998). Although much of our knowledge on th... |
Psoriasis is a chronic immune - mediated skin disease with a prevalence varying among ethnic groups from 0.91% to 8.5% . Psoriatic arthritis (psa) is a chronic inflammatory disease affecting about 6 - 10% of patients with cutaneous psoriasis . However, the prevalence of psa is significantly higher (20 - 40%) in patient... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.